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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:homopolymer macromolecule
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Accession:CHEBI:37997 term browser browse the term
Definition:A macromolecule derived from one species of (real, implicit or hypothetical) monomer.
Synonyms:exact_synonym: homopolymer
 related_synonym: homopolymer molecule;   homopolymer molecules;   homopolymers


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colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein decreases expression ISO Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
ISO Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA
CTD PMID:22120639 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
gamma-poly(L-glutamic acid) macromolecule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene decreases secretion ISO DEK protein results in decreased secretion of Polyglutamic Acid CTD PMID:28558019 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects localization EXP Polyglutamic Acid affects the localization of HSPA8 protein CTD PMID:10469394 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
poly(ethene-1,2-diyl) macromolecule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO Polyynes results in decreased activity of ABCB1 protein CTD PMID:18425719 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
poly(ethylene) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant decreases expression ISO Polyethylene results in decreased expression of ACP5 mRNA CTD PMID:15585240 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 decreases expression ISO Polyethylene results in decreased expression of ASCL1 mRNA CTD PMID:23203475 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Polyethylene results in decreased expression of BGLAP protein CTD PMID:10225790 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Polyethylene results in decreased expression of COL1A1 mRNA CTD PMID:11216681 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Csf2 colony stimulating factor 2 affects secretion ISO Polyethylene affects the secretion of CSF2 protein CTD PMID:15046894 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Polyethylene results in decreased expression of FOS mRNA CTD PMID:15585240 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxg1 forkhead box G1 decreases expression ISO Polyethylene results in decreased expression of FOXG1 mRNA CTD PMID:23203475 NCBI chr 6:69,971,227...69,974,037
Ensembl chr 6:69,971,227...69,974,037
JBrowse link
G Hes5 hes family bHLH transcription factor 5 decreases expression ISO Polyethylene results in decreased expression of HES5 mRNA CTD PMID:23203475 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Polyethylene analog promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:10602080 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Polyethylene results in increased expression of IL6 mRNA; Polyethylene results in increased expression of IL6 protein
Polyethylene analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:10602080, PMID:11771709 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Polyethylene results in increased expression of LITAF mRNA CTD PMID:17408380 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Neurod1 neuronal differentiation 1 decreases expression ISO Polyethylene results in decreased expression of NEUROD1 mRNA CTD PMID:23203475 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Polyethylene results in decreased expression of NOTCH1 mRNA CTD PMID:23203475 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression ISO Polyethylene results in increased expression of SRC mRNA CTD PMID:15585240 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
affects secretion
ISO Polyethylene results in increased expression of TNF mRNA
Polyethylene analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Polyethylene affects the secretion of TNF protein
Etidronic Acid inhibits the reaction [Polyethylene affects the secretion of TNF protein]; ibandronic acid inhibits the reaction [Polyethylene affects the secretion of TNF protein]
CTD PMID:10413987, PMID:10602080, PMID:17408380 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression
decreases secretion
ISO Polyethylene results in decreased expression of TNFRSF11B protein
Polyethylene results in decreased secretion of TNFRSF11B protein
CTD PMID:15046894, PMID:15585240 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfsf11 TNF superfamily member 11 affects secretion
increases secretion
ISO Polyethylene affects the secretion of TNFSF11 protein
Polyethylene results in increased secretion of TNFSF11 protein
CTD PMID:15046894, PMID:15585240 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
poly(propylene imine) macromolecule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase decreases expression ISO poly(propyleneimine) analog results in decreased expression of ALOX5 mRNA CTD PMID:16308212 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Anxa2 annexin A2 increases expression ISO poly(propyleneimine) analog results in increased expression of ANXA2 mRNA CTD PMID:16308212 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Ccna1 cyclin A1 increases expression ISO poly(propyleneimine) analog results in increased expression of CCNA1 mRNA CTD PMID:16308212 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Cd14 CD14 molecule increases expression ISO poly(propyleneimine) analog results in increased expression of CD14 mRNA CTD PMID:16308212 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd27 CD27 molecule decreases expression ISO poly(propyleneimine) analog results in decreased expression of CD27 mRNA CTD PMID:16308212 NCBI chr 4:157,744,881...157,751,609
Ensembl chr 4:157,744,882...157,750,088
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO poly(propyleneimine) analog results in decreased expression of CDK1 mRNA CTD PMID:16308212 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO poly(propyleneimine) analog results in increased expression of CDK4 mRNA CTD PMID:16308212 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO poly(propyleneimine) analog results in decreased expression of DBF4 mRNA CTD PMID:16308212 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO poly(propyleneimine) analog results in decreased expression of DUSP1 mRNA CTD PMID:16308212 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Gmps guanine monophosphate synthase decreases expression ISO poly(propyleneimine) analog results in decreased expression of GMPS mRNA CTD PMID:16308212 NCBI chr 2:154,555,967...154,590,662
Ensembl chr 2:154,555,871...154,590,662
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression ISO poly(propyleneimine) analog results in increased expression of HSP90B1 mRNA CTD PMID:16308212 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO poly(propyleneimine) analog results in decreased expression of HSPD1 mRNA CTD PMID:16308212 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ik IK cytokine decreases expression ISO poly(propyleneimine) analog results in decreased expression of IK mRNA CTD PMID:16308212 NCBI chr18:29,587,901...29,602,705
Ensembl chr18:29,587,901...29,608,338
JBrowse link
G Il9r interleukin 9 receptor increases expression ISO poly(propyleneimine) analog results in increased expression of IL9R mRNA CTD PMID:16308212 NCBI chr10:15,697,216...15,708,684
Ensembl chr10:15,696,824...15,710,423
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase affects expression ISO poly(propyleneimine) analog affects the expression of MET mRNA CTD PMID:16308212 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta decreases expression ISO poly(propyleneimine) analog results in decreased expression of PCCB mRNA CTD PMID:16308212 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO poly(propyleneimine) analog results in decreased expression of PCNA mRNA CTD PMID:16308212 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 increases expression ISO poly(propyleneimine) analog results in increased expression of PSMA4 mRNA CTD PMID:16308212 NCBI chr 8:59,532,456...59,539,916
Ensembl chr 8:59,532,389...59,539,920
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 decreases expression ISO poly(propyleneimine) analog results in decreased expression of PSMB4 mRNA CTD PMID:16308212 NCBI chr 2:196,043,546...196,046,320
Ensembl chr 2:196,043,618...196,046,311
JBrowse link
G Rpa3 replication protein A3 decreases expression ISO poly(propyleneimine) analog results in decreased expression of RPA3 mRNA CTD PMID:16308212 NCBI chr 4:34,279,320...34,282,351
Ensembl chr 4:34,279,320...34,282,351
JBrowse link
G Rpl8 ribosomal protein L8 decreases expression ISO poly(propyleneimine) analog results in decreased expression of RPL8 mRNA CTD PMID:16308212 NCBI chr 7:117,967,608...117,969,886
Ensembl chr 7:118,507,224...118,509,256
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO poly(propyleneimine) analog results in increased expression of RXRA mRNA CTD PMID:16308212 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 decreases expression ISO poly(propyleneimine) analog results in decreased expression of SMARCA4 mRNA CTD PMID:16308212 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO poly(propyleneimine) analog results in increased expression of TGFA mRNA CTD PMID:16308212 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tpr translocated promoter region, nuclear basket protein increases expression ISO poly(propyleneimine) analog results in increased expression of TPR mRNA CTD PMID:16308212 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Tubb4a tubulin, beta 4A class IVa increases expression ISO poly(propyleneimine) analog results in increased expression of TUBB4A mRNA CTD PMID:16308212 NCBI chr 9:9,961,020...9,968,420
Ensembl chr 9:9,961,021...9,968,486
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta decreases expression ISO poly(propyleneimine) analog results in decreased expression of YWHAQ mRNA CTD PMID:16308212 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link
poly(styrene) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 increases expression ISO styrofoam analog results in increased expression of C3 protein CTD PMID:19428933 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 increases expression ISO styrofoam analog results in increased expression of C5 protein CTD PMID:19428933 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects activity
ISO styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP1A2 protein]
styrofoam analog affects the activity of CYP1A2 protein
CTD PMID:19909766 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
multiple interactions
ISO styrofoam analog results in decreased activity of CYP2D6 protein
styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP2D6 protein]
CTD PMID:19909766 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO styrofoam analog results in increased expression of ITGAM protein CTD PMID:19428933 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Pf4 platelet factor 4 increases secretion ISO styrofoam analog results in increased secretion of PF4 protein CTD PMID:19428933 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Ppbp pro-platelet basic protein increases secretion ISO styrofoam analog results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315
JBrowse link
G Selp selectin P increases expression ISO styrofoam results in increased expression of SELP protein CTD PMID:21123846 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
poly(vinyl chloride) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 decreases expression ISO Polyvinyl Chloride results in decreased expression of ANGPT1 mRNA CTD PMID:12809767 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
poly(vinylpyrrolidone) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5mc2 ATP synthase membrane subunit c locus 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of ATP5MC2 mRNA CTD PMID:25194297 NCBI chr 7:144,264,207...144,272,578
Ensembl chr 7:144,264,199...144,272,578
JBrowse link
G Bola3 bolA family member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of BOLA3 mRNA CTD PMID:25194297 NCBI chr 4:115,046,693...115,056,140
Ensembl chr 4:115,046,693...115,056,140
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Silver co-treated with Povidone] affects the expression of CASP3 protein; [Silver co-treated with Povidone] results in decreased expression of CASP3 mRNA CTD PMID:27387714 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA; [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein CTD PMID:27387714 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of COL8A1 mRNA CTD PMID:25194297 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of COX17 mRNA CTD PMID:25194297 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of CYP1A1 mRNA CTD PMID:25194297 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dad1 defender against cell death 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA CTD PMID:25194297 NCBI chr15:32,868,136...32,887,933
Ensembl chr15:32,868,087...32,888,095
JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of GBP2 mRNA CTD PMID:25194297 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of H2AX protein modified form CTD PMID:27387714 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of HMOX1 mRNA CTD PMID:25194297 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA CTD PMID:25194297 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Lims1 LIM zinc finger domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of LIMS1 mRNA CTD PMID:25194297 NCBI chr20:27,895,981...28,004,767
Ensembl chr20:27,954,433...28,002,082
JBrowse link
G Lmnb2 lamin B2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of LMNB2 mRNA CTD PMID:25194297 NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK1 protein CTD PMID:21729742 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK3 protein CTD PMID:21729742 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA CTD PMID:27387714 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mt1 metallothionein 1 multiple interactions EXP [Silver analog co-treated with Povidone] affects the expression of MT1A mRNA CTD PMID:25194297 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Nfix nuclear factor I X multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NFIX mRNA CTD PMID:25194297 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NQO1 mRNA CTD PMID:25194297 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nrm nurim multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NRM mRNA CTD PMID:25194297 NCBI chr20:3,397,834...3,402,264
Ensembl chr20:3,397,834...3,401,315
JBrowse link
G Nuak2 NUAK family kinase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NUAK2 mRNA CTD PMID:25194297 NCBI chr13:49,092,306...49,109,055
Ensembl chr13:49,092,306...49,109,050
JBrowse link
G Ocln occludin affects expression ISO Povidone affects the expression of OCLN mRNA CTD PMID:19729060 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Prpf38b pre-mRNA processing factor 38B multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRPF38B mRNA CTD PMID:25194297 NCBI chr 2:211,706,245...211,715,271
Ensembl chr 2:211,706,228...211,715,311
JBrowse link
G Prr13 proline rich 13 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRR13 mRNA CTD PMID:25194297 NCBI chr 7:144,064,931...144,068,235
Ensembl chr 7:144,064,931...144,098,101
JBrowse link
G Psenen presenilin enhancer gamma secretase subunit multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PSENEN mRNA CTD PMID:25194297 NCBI chr 1:89,016,093...89,017,449
Ensembl chr 1:89,016,096...89,017,290
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of PTGS2 mRNA CTD PMID:25194297 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein CTD PMID:21729742 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rab14 RAB14, member RAS oncogene family multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RAB14 mRNA CTD PMID:25194297 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
G Rbm25l1 RNA binding motif protein 25-like 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RBM25L1 mRNA CTD PMID:25194297 NCBI chr10:10,457,316...10,460,540
Ensembl chr10:10,457,320...10,460,756
JBrowse link
G Selenow selenoprotein W multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SELENOW mRNA CTD PMID:25194297 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SLC5A3 mRNA CTD PMID:25194297 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of SOD2 mRNA; [Silver co-treated with Povidone] results in increased expression of SOD2 protein CTD PMID:27387714 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SPARC mRNA CTD PMID:25194297 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of STAT2 mRNA CTD PMID:25194297 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SV2B mRNA CTD PMID:25194297 NCBI chr 1:136,664,199...136,842,247
Ensembl chr 1:136,664,204...136,842,247
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TIPARP mRNA CTD PMID:25194297 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TMTC3 mRNA CTD PMID:25194297 NCBI chr 7:40,171,957...40,217,056
Ensembl chr 7:40,171,963...40,217,056
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results in decreased expression of TP53 mRNA; [Silver co-treated with Povidone] results in decreased expression of TP53 protein CTD PMID:27387714 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trappc1 trafficking protein particle complex 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of TRAPPC1 mRNA CTD PMID:25194297 NCBI chr10:55,924,996...55,926,582
Ensembl chr10:55,924,938...55,926,783
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of VEGFA protein CTD PMID:21729742 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA CTD PMID:25194297 NCBI chr 9:85,477,070...85,528,885
Ensembl chr 9:85,475,841...85,528,869
JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of ZFHX3 mRNA CTD PMID:25194297 NCBI chr19:42,753,983...42,925,794
Ensembl chr19:42,758,127...42,920,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      molecular entity 19814
        polyatomic entity 19727
          macromolecule 3316
            homopolymer macromolecule 102
              gamma-poly(glutamic acid) macromolecule + 2
              homopolymer + 0
              omega-hydroxypoly(furan-2,5-diylmethylene) macromolecule + 0
              oxidised poly(vinyl alcohol) 0
              poly(2,7-carbozolene vinylene) macromolecule + 0
              poly(2-hydroxyethyl methacrylate) macromolecule + 0
              poly(2-methacrylolyloxyethyltrimethylammonium chloride) macromolecule + 0
              poly(2-oxazoline) macromolecule + 0
              poly(3-hydroxycarboxylic acid) macromolecule + 0
              poly(N,N'-methylenebisacrylamide) macromolecule + 0
              poly(alkylene vinylene) macromolecule + 0
              poly(alkylene) macromolecule + 72
              poly(caprolactone) macromolecule + 0
              poly(chloroprene) macromolecule + 0
              poly(diallyldimethylammonium chloride) macromolecule + 0
              poly(diallylmethylammonium chloride) macromolecule + 0
              poly(divinylbenzene) macromolecule + 0
              poly(ethyl ethoxyethylene phosphate) macromolecule + 0
              poly(galactose) macromolecule + 0
              poly(glycerol phosphate) anion macromolecule 0
              poly(glycerol phosphate) macromolecule + 0
              poly(glycidyl methacrylate) macromolecule + 0
              poly(isobornyl acrylate) macromolecule + 0
              poly(lactic acid) macromolecule + 0
              poly(menthide) macromolecule + 0
              poly(metallocene) macromolecule + 0
              poly(methacrylic acid) macromolecule + 0
              poly(methyl acrylate) macromolecule + 0
              poly(phenylene) macromolecule + 0
              poly(phenylenevinylene) macromolecule + 0
              poly(phosphazene) macromolecule + 0
              poly(propylene imine) macromolecule + 27
              poly(selenophene-2,5-diyl) macromolecule + 0
              poly(sulfone) macromolecule + 0
              poly(triphenylamine) macromolecule + 0
              poly(vinyl alcohol) macromolecule + 0
              poly(xylylviologen) macromolecule + 0
              poly[2-(2-methoxyethoxy)ethyl methacrylate] macromolecule + 0
              poly[B-(methylamino)borazine] macromolecule + 0
              polyacetylene macromolecule + 1
              polyalkenylene macromolecule + 0
              polyanethol sulfonic acid macromolecule + 0
              polybenzoxazole macromolecule + 0
              polycarbazole macromolecule + 0
              polyfluorene macromolecule + 0
              polyhexamethylene biguanide 0
              polyisocyanide macromolecule + 0
              polyphenylene ethynylene macromolecule + 0
              polythiophene macromolecule + 0
              polythiourethane macromolecule + 0
              polyurethane macromolecule + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  group 19728
                    polyatomic entity 19727
                      macromolecule 3316
                        homopolymer macromolecule 102
                          gamma-poly(glutamic acid) macromolecule + 2
                          homopolymer + 0
                          omega-hydroxypoly(furan-2,5-diylmethylene) macromolecule + 0
                          oxidised poly(vinyl alcohol) 0
                          poly(2,7-carbozolene vinylene) macromolecule + 0
                          poly(2-hydroxyethyl methacrylate) macromolecule + 0
                          poly(2-methacrylolyloxyethyltrimethylammonium chloride) macromolecule + 0
                          poly(2-oxazoline) macromolecule + 0
                          poly(3-hydroxycarboxylic acid) macromolecule + 0
                          poly(N,N'-methylenebisacrylamide) macromolecule + 0
                          poly(alkylene vinylene) macromolecule + 0
                          poly(alkylene) macromolecule + 72
                          poly(caprolactone) macromolecule + 0
                          poly(chloroprene) macromolecule + 0
                          poly(diallyldimethylammonium chloride) macromolecule + 0
                          poly(diallylmethylammonium chloride) macromolecule + 0
                          poly(divinylbenzene) macromolecule + 0
                          poly(ethyl ethoxyethylene phosphate) macromolecule + 0
                          poly(galactose) macromolecule + 0
                          poly(glycerol phosphate) anion macromolecule 0
                          poly(glycerol phosphate) macromolecule + 0
                          poly(glycidyl methacrylate) macromolecule + 0
                          poly(isobornyl acrylate) macromolecule + 0
                          poly(lactic acid) macromolecule + 0
                          poly(menthide) macromolecule + 0
                          poly(metallocene) macromolecule + 0
                          poly(methacrylic acid) macromolecule + 0
                          poly(methyl acrylate) macromolecule + 0
                          poly(phenylene) macromolecule + 0
                          poly(phenylenevinylene) macromolecule + 0
                          poly(phosphazene) macromolecule + 0
                          poly(propylene imine) macromolecule + 27
                          poly(selenophene-2,5-diyl) macromolecule + 0
                          poly(sulfone) macromolecule + 0
                          poly(triphenylamine) macromolecule + 0
                          poly(vinyl alcohol) macromolecule + 0
                          poly(xylylviologen) macromolecule + 0
                          poly[2-(2-methoxyethoxy)ethyl methacrylate] macromolecule + 0
                          poly[B-(methylamino)borazine] macromolecule + 0
                          polyacetylene macromolecule + 1
                          polyalkenylene macromolecule + 0
                          polyanethol sulfonic acid macromolecule + 0
                          polybenzoxazole macromolecule + 0
                          polycarbazole macromolecule + 0
                          polyfluorene macromolecule + 0
                          polyhexamethylene biguanide 0
                          polyisocyanide macromolecule + 0
                          polyphenylene ethynylene macromolecule + 0
                          polythiophene macromolecule + 0
                          polythiourethane macromolecule + 0
                          polyurethane macromolecule + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.