|
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|
Abcc3
|
ATP binding cassette subfamily C member 3
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of ABCC3 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
increases activity increases expression
|
ISO
|
4-phenylenediamine results in increased activity of AKR1C2 promoter 4-phenylenediamine results in increased expression of AKR1C2 mRNA
|
CTD |
PMID:20491607 PMID:21195160 PMID:25724174 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Anxa1
|
annexin A1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of ANXA1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
|
|
| G
|
Aqp3
|
aquaporin 3 (Gill blood group)
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of AQP3 mRNA
|
CTD |
PMID:15140218 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
|
|
| G
|
Astl
|
astacin like metalloendopeptidase
|
affects localization
|
ISO
|
4-phenylenediamine affects the localization of ASTL protein
|
CTD |
PMID:35363429 |
|
NCBI chr 3:135,016,444...135,032,177
Ensembl chr 3:135,016,444...135,032,177
|
|
| G
|
Atf3
|
activating transcription factor 3
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of ATF3 mRNA
|
CTD |
PMID:16314067 PMID:23999411 PMID:27965148 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
|
|
| G
|
Bach1
|
BTB domain and CNC homolog 1
|
multiple interactions
|
ISO
|
BACH1 mRNA promotes the reaction [4-phenylenediamine results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:26244607 |
|
NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277
|
|
| G
|
Casp1
|
caspase 1
|
multiple interactions increases activity
|
ISO
|
4-phenylenediamine promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] 4-phenylenediamine results in increased activity of CASP1 protein
|
CTD |
PMID:31276767 |
|
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
|
|
| G
|
Casp3
|
caspase 3
|
increases activity
|
ISO
|
4-phenylenediamine results in increased activity of CASP3 protein
|
CTD |
PMID:26784575 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
increases expression increases secretion multiple interactions
|
ISO
|
4-phenylenediamine results in increased expression of CCL2 protein 4-phenylenediamine results in increased secretion of CCL2 protein MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of CCL2 protein]
|
CTD |
PMID:22245253 PMID:34826398 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CCL4 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CCL5 mRNA
|
CTD |
PMID:27585668 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Ccl7
|
C-C motif chemokine ligand 7
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CCL7 mRNA
|
CTD |
PMID:27585668 |
|
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
|
|
| G
|
Ccr2
|
C-C motif chemokine receptor 2
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of CCR2 mRNA
|
CTD |
PMID:19371601 |
|
NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059
|
|
| G
|
Ccr6
|
C-C motif chemokine receptor 6
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of CCR6 protein
|
CTD |
PMID:15924226 |
|
NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059
|
|
| G
|
Cd274
|
CD274 molecule
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CD274 protein
|
CTD |
PMID:20488241 |
|
NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951
|
|
| G
|
Cd86
|
CD86 molecule
|
multiple interactions increases expression
|
ISO
|
bisindolylmaleimide I inhibits the reaction [4-phenylenediamine results in increased expression of CD86 protein]
|
CTD |
PMID:12423654 PMID:19033392 PMID:19665512 PMID:20488241 PMID:24136171 PMID:32006680 More...
|
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CDKN1A mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Crem
|
cAMP responsive element modulator
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CREM mRNA
|
CTD |
PMID:19371601 |
|
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
increases secretion
|
ISO
|
4-phenylenediamine results in increased secretion of CSF2 protein
|
CTD |
PMID:22245253 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Cxcl1
|
C-X-C motif chemokine ligand 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CXCL1 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of CXCL10 mRNA
|
CTD |
PMID:23445166 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
|
Cxcl14
|
C-X-C motif chemokine ligand 14
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of CXCL14 protein
|
CTD |
PMID:31734321 |
|
NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CXCL2 protein
|
CTD |
PMID:23178550 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CXCL1 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of CXCR4 protein
|
CTD |
PMID:15924226 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cytip
|
cytohesin 1 interacting protein
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of CYTIP mRNA
|
CTD |
PMID:19371601 |
|
NCBI chr 3:63,106,895...63,183,769
Ensembl chr 3:63,107,607...63,134,832
|
|
| G
|
Dnajb4
|
DnaJ heat shock protein family (Hsp40) member B4
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of DNAJB4 mRNA
|
CTD |
PMID:23999411 PMID:27965148 |
|
NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042
|
|
| G
|
Dusp1
|
dual specificity phosphatase 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of DUSP1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
|
|
| G
|
Fth1
|
ferritin heavy chain 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of FTH1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
|
|
| G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of GCLM mRNA
|
CTD |
PMID:16314067 PMID:23999411 PMID:27965148 |
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
increases metabolic processing
|
ISO
|
4-phenylenediamine results in increased metabolism of GSTP1 protein
|
CTD |
PMID:19469519 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Has1
|
hyaluronan synthase 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HAS1 mRNA; 4-phenylenediamine results in increased expression of HAS1 protein
|
CTD |
PMID:31226360 |
|
NCBI chr 1:67,366,460...67,378,686
Ensembl chr 1:67,366,460...67,378,444
|
|
| G
|
Has2
|
hyaluronan synthase 2
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HAS2 mRNA; 4-phenylenediamine results in increased expression of HAS2 protein
|
CTD |
PMID:31226360 |
|
NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535
|
|
| G
|
Has3
|
hyaluronan synthase 3
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HAS3 mRNA; 4-phenylenediamine results in increased expression of HAS3 protein
|
CTD |
PMID:31226360 |
|
NCBI chr19:51,668,276...51,691,042
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HIF1A mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
increases expression multiple interactions
|
ISO
|
4-phenylenediamine results in increased expression of HMOX1 mRNA BACH1 mRNA promotes the reaction [4-phenylenediamine results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [4-phenylenediamine results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:16314067 PMID:19033392 PMID:20491607 PMID:20713136 PMID:23445166 PMID:25724174 PMID:26244607 PMID:31967339 More...
|
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hspa6l-ps1
|
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HSPA6 mRNA
|
CTD |
PMID:23999411 |
|
NCBI chr13:85,805,911...85,807,052
|
|
| G
|
Hsph1
|
heat shock protein family H (Hsp110) member 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HSPH1 mRNA
|
CTD |
PMID:23999411 |
|
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
|
|
| G
|
Htatip2
|
HIV-1 Tat interactive protein 2
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HTATIP2 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815
|
|
| G
|
Hyal1
|
hyaluronidase 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of HYAL1 mRNA
|
CTD |
PMID:31226360 |
|
NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:117,129,277...117,133,146
|
|
| G
|
Ifng
|
interferon gamma
|
increases expression increases secretion
|
ISO
|
4-phenylenediamine results in increased expression of IFNG mRNA 4-phenylenediamine results in increased secretion of IFNG protein
|
CTD |
PMID:11531941 PMID:22245253 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Il10
|
interleukin 10
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of IL10 mRNA
|
CTD |
PMID:11531941 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il17f
|
interleukin 17F
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of IL17F mRNA
|
CTD |
PMID:23445166 |
|
NCBI chr 9:30,686,532...30,697,918
Ensembl chr 9:30,686,538...30,697,918
|
|
| G
|
Il18
|
interleukin 18
|
increases expression multiple interactions
|
ISO
|
4-phenylenediamine results in increased expression of IL18 protein PRDM1 protein promotes the reaction [4-phenylenediamine results in increased expression of IL18 protein]
|
CTD |
PMID:23063874 PMID:27585668 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
|
|
| G
|
Il1a
|
interleukin 1 alpha
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of IL1A protein
|
CTD |
PMID:23178550 |
|
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
|
|
| G
|
Il1b
|
interleukin 1 beta
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of IL1B mRNA
|
CTD |
PMID:15140218 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il2
|
interleukin 2
|
increases secretion
|
ISO
|
4-phenylenediamine results in increased secretion of IL2 protein
|
CTD |
PMID:22245253 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il4
|
interleukin 4
|
increases expression increases secretion
|
ISO
|
4-phenylenediamine results in increased expression of IL4 mRNA 4-phenylenediamine results in increased secretion of IL4 protein
|
CTD |
PMID:11531941 PMID:22245253 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Il6
|
interleukin 6
|
increases secretion
|
ISO
|
4-phenylenediamine results in increased secretion of IL6 protein
|
CTD |
PMID:22245253 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Izumo1r
|
IZUMO1 receptor, JUNO
|
multiple interactions
|
ISO
|
4-phenylenediamine results in decreased expression of and results in decreased localization of IZUMO1R protein
|
CTD |
PMID:35363429 |
|
NCBI chr 8:20,025,830...20,030,829
Ensembl chr 8:20,025,831...20,029,578
|
|
| G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
multiple interactions
|
ISO
|
KIT protein mutant form inhibits the reaction [4-phenylenediamine results in increased expression of TPSB2 protein]
|
CTD |
PMID:34826398 |
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
|
|
| G
|
Lrp6
|
LDL receptor related protein 6
|
decreases phosphorylation
|
ISO
|
4-phenylenediamine results in decreased phosphorylation of LRP6 protein
|
CTD |
PMID:26784575 |
|
NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
increases phosphorylation
|
ISO
|
4-phenylenediamine results in increased phosphorylation of MAPK1 protein
|
CTD |
PMID:34826398 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
increases phosphorylation
|
ISO
|
4-phenylenediamine results in increased phosphorylation of MAPK3 protein
|
CTD |
PMID:34826398 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Mapk8
|
mitogen-activated protein kinase 8
|
increases phosphorylation
|
ISO
|
4-phenylenediamine results in increased phosphorylation of MAPK8 protein
|
CTD |
PMID:23172806 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
|
|
| G
|
Mapk9
|
mitogen-activated protein kinase 9
|
increases phosphorylation
|
ISO
|
4-phenylenediamine results in increased phosphorylation of MAPK9 protein
|
CTD |
PMID:23172806 |
|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
|
|
| G
|
Me1
|
malic enzyme 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of ME1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
|
|
| G
|
Mlst8
|
MTOR associated protein, LST8 homolog
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of MLST8 protein
|
CTD |
PMID:26784575 |
|
NCBI chr10:14,002,927...14,008,678
Ensembl chr10:14,002,938...14,008,678
|
|
| G
|
Mrgprx2
|
MAS related GPR family member X2
|
affects response to substance multiple interactions
|
ISO
|
MRGPRX2 protein affects the susceptibility to 4-phenylenediamine MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of CCL2 protein]; MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of CXCL8 protein]; MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of TNF protein]; MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of TPSB2 protein]
|
CTD |
PMID:34826398 |
|
NCBI chr 1:107,252,467...107,271,809
|
|
| G
|
Mt2
|
metallothionein 2
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of MT2A mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
affects phosphorylation
|
ISO
|
4-phenylenediamine affects the phosphorylation of MTOR protein
|
CTD |
PMID:26784575 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Nat1
|
N-acetyltransferase 1
|
increases acetylation multiple interactions
|
ISO
|
NAT1 protein results in increased acetylation of 4-phenylenediamine 4-phenylenediamine results in decreased activity of and results in decreased expression of NAT1 protein
|
CTD |
PMID:15350687 PMID:20406859 |
|
NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
|
|
| G
|
Nat2
|
N-acetyltransferase 2
|
affects response to substance
|
ISO
|
NAT2 gene polymorphism affects the susceptibility to 4-phenylenediamine
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CTD |
PMID:16533241 |
|
NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304
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| G
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Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
increases expression multiple interactions decreases expression
|
ISO
|
4-phenylenediamine results in increased expression of NFE2L2 protein NFE2L2 mRNA promotes the reaction [4-phenylenediamine results in increased expression of HMOX1 mRNA] 4-phenylenediamine results in decreased expression of NFE2L2 mRNA
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CTD |
PMID:19033392 PMID:26244607 PMID:31967339 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
decreases phosphorylation
|
ISO
|
4-phenylenediamine results in decreased phosphorylation of NFKBIA protein
|
CTD |
PMID:26784575 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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|
| G
|
Ninj1
|
ninjurin 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of NINJ1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,659,200...15,668,063
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|
| G
|
Nlrp12
|
NLR family, pyrin domain containing 12
|
increases expression multiple interactions decreases expression
|
ISO
|
4-phenylenediamine results in increased expression of NLRP12 mRNA 4-phenylenediamine promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] 4-phenylenediamine results in decreased expression of NLRP12 protein
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CTD |
PMID:27585668 PMID:31276767 |
|
NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341
|
|
| G
|
Nlrp3
|
NLR family, pyrin domain containing 3
|
multiple interactions increases expression
|
ISO
|
4-phenylenediamine promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] 4-phenylenediamine results in increased expression of NLRP3 protein
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CTD |
PMID:31276767 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
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|
| G
|
Nlrx1
|
NLR family member X1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of NLRX1 mRNA
|
CTD |
PMID:27585668 |
|
NCBI chr 8:53,486,866...53,503,498
Ensembl chr 8:53,486,867...53,503,523
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|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of NQO1 mRNA
|
CTD |
PMID:16314067 PMID:19033392 PMID:23445166 PMID:25724174 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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|
| G
|
Pgd
|
phosphogluconate dehydrogenase
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PGD mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
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|
| G
|
Piga
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phosphatidylinositol glycan anchor biosynthesis, class A
|
increases mutagenesis
|
EXP
|
4-phenylenediamine results in increased mutagenesis of PIGA gene
|
CTD |
PMID:30439388 |
|
NCBI chr X:33,672,832...33,687,747
Ensembl chr X:33,674,923...33,687,636
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|
| G
|
Pir
|
pirin
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PIR mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr X:33,740,428...33,851,049
Ensembl chr X:33,740,429...33,851,049
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|
| G
|
Plin2
|
perilipin 2
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PLIN2 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878
|
|
| G
|
Pmaip1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PMAIP1 mRNA
|
CTD |
PMID:16314067 PMID:20713136 |
|
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PPARG mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Prdm1
|
PR/SET domain 1
|
multiple interactions increases expression
|
ISO
|
BAY 11-7085 inhibits the reaction [4-phenylenediamine results in increased expression of PRDM1 mRNA]; BAY 11-7085 inhibits the reaction [4-phenylenediamine results in increased expression of PRDM1 protein]; PRDM1 protein promotes the reaction [4-phenylenediamine results in increased expression of IL18 protein] 4-phenylenediamine results in increased expression of PRDM1 mRNA; 4-phenylenediamine results in increased expression of PRDM1 protein
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CTD |
PMID:27585668 PMID:31276767 |
|
NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088
|
|
| G
|
Prdx3
|
peroxiredoxin 3
|
multiple interactions
|
ISO
|
4-phenylenediamine promotes the reaction [Gentamicins results in increased expression of PRDX3 protein]
|
CTD |
PMID:23626763 |
|
NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300
|
|
| G
|
Ptgs1
|
prostaglandin-endoperoxide synthase 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PTGS1 mRNA
|
CTD |
PMID:18571826 |
|
NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990
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|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of PTGS2 mRNA
|
CTD |
PMID:18571826 PMID:19371601 PMID:20713136 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Pycard
|
PYD and CARD domain containing
|
multiple interactions increases expression
|
ISO
|
4-phenylenediamine promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] 4-phenylenediamine results in increased expression of PYCARD protein
|
CTD |
PMID:31276767 |
|
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
increases phosphorylation multiple interactions
|
ISO
|
4-phenylenediamine results in increased phosphorylation of RELA protein aristolochic acid I inhibits the reaction [4-phenylenediamine results in increased phosphorylation of RELA protein]; TLR4 protein promotes the reaction [4-phenylenediamine results in increased phosphorylation of RELA protein]
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CTD |
PMID:31226360 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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|
| G
|
Rgs1
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regulator of G-protein signaling 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of RGS1 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr13:58,568,844...58,573,187
Ensembl chr13:58,568,844...58,573,187
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|
| G
|
Rictor
|
RPTOR independent companion of MTOR, complex 2
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of RICTOR protein
|
CTD |
PMID:26784575 |
|
NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:57,539,311...57,631,288
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|
| G
|
Rit1
|
Ras-like without CAAX 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of RIT1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 2:176,478,616...176,493,269
Ensembl chr 2:176,478,596...176,494,684
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|
| G
|
Rptor
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regulatory associated protein of MTOR, complex 1
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of RPTOR protein
|
CTD |
PMID:26784575 |
|
NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413
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|
| G
|
Si
|
sucrase-isomaltase
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of SI mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr 2:159,804,568...159,884,902
Ensembl chr 2:159,804,568...159,883,934
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|
| G
|
Slamf1
|
signaling lymphocytic activation molecule family member 1
|
decreases expression
|
ISO
|
4-phenylenediamine results in decreased expression of SLAMF1 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr13:86,802,708...86,837,890
Ensembl chr13:86,802,708...86,837,890
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|
| G
|
Slc2a3
|
solute carrier family 2 member 3
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of SLC2A3 mRNA
|
CTD |
PMID:19371601 |
|
NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186
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|
| G
|
Spta1
|
spectrin, alpha, erythrocytic 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of SPTA1 mRNA
|
CTD |
PMID:16314067 |
|
NCBI chr13:88,735,833...88,811,697
Ensembl chr13:88,735,833...88,811,697
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|
| G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions increases expression
|
ISO
|
TLR4 protein promotes the reaction [4-phenylenediamine results in increased phosphorylation of RELA protein] 4-phenylenediamine results in increased expression of TLR4 mRNA; 4-phenylenediamine results in increased expression of TLR4 protein
|
CTD |
PMID:31226360 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
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|
| G
|
Tnf
|
tumor necrosis factor
|
affects response to substance increases secretion multiple interactions increases expression
|
ISO
|
TNF gene polymorphism affects the susceptibility to 4-phenylenediamine 4-phenylenediamine results in increased secretion of TNF protein MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of TNF protein] 4-phenylenediamine results in increased expression of TNF protein
|
CTD |
PMID:18384449 PMID:22245253 PMID:34826398 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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|
| G
|
Tnfaip3
|
TNF alpha induced protein 3
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of TNFAIP3 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979
|
|
| G
|
Tnfaip6
|
TNF alpha induced protein 6
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of TNFAIP6 mRNA
|
CTD |
PMID:20713136 |
|
NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796
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|
| G
|
Tpsb2
|
tryptase beta 2
|
multiple interactions increases expression increases secretion
|
ISO
|
KIT protein mutant form inhibits the reaction [4-phenylenediamine results in increased expression of TPSB2 protein] MRGPRX2 protein affects the reaction [4-phenylenediamine results in increased secretion of TPSB2 protein]
|
CTD |
PMID:34826398 |
|
NCBI chr10:14,886,310...14,888,102
Ensembl chr10:14,886,360...14,888,100
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|
| G
|
Txnrd1
|
thioredoxin reductase 1
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of TXNRD1 mRNA
|
CTD |
PMID:23445166 |
|
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
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|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
ISO
|
4-phenylenediamine results in increased expression of VEGFA protein
|
CTD |
PMID:9390328 PMID:25617811 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
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|
|
|
| G
|
Abcc4
|
ATP binding cassette subfamily C member 4
|
multiple interactions
|
ISO
|
Mefloquine inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]
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CTD |
PMID:16004972 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
|
|
| G
|
Abcc5
|
ATP binding cassette subfamily C member 5
|
increases export multiple interactions
|
ISO
|
ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; hesperetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Quercetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; resveratrol inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Silymarin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]
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CTD |
PMID:16156793 |
|
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
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|
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions decreases activity
|
ISO
|
bisbenzimide ethoxide trihydrochloride inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCB11 protein
|
CTD |
PMID:24014644 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
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|
| G
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Abcb1a
|
ATP binding cassette subfamily B member 1A
|
increases transport multiple interactions
|
ISO
|
ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride abamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride] [zosuquidar trihydrochloride results in decreased activity of ABCB1 protein] which results in decreased export of bisbenzimide ethoxide trihydrochloride; abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
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CTD |
PMID:25865432 PMID:34896433 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
increases transport multiple interactions
|
ISO
|
ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride abamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
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CTD |
PMID:25865432 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
decreases abundance decreases export decreases activity multiple interactions increases export increases transport
|
ISO
|
ABCG2 protein results in decreased abundance of bisbenzimide ethoxide trihydrochloride ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCG2 protein 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased export of bisbenzimide ethoxide trihydrochloride; [bisphenol A results in decreased activity of ABCG2 protein] which results in decreased transport of bisbenzimide ethoxide trihydrochloride; [MLN 8237 affects the activity of ABCG2 protein] which affects the export of bisbenzimide ethoxide trihydrochloride; [MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride; Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Cyclosporine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Genistein inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride]; Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Porphyrins inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Tobacco Smoke Pollution inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; verlukast inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
|
CTD |
PMID:12869632 PMID:19239227 PMID:26850786 PMID:26907376 PMID:27450509 PMID:27475308 PMID:34073890 PMID:34717915 PMID:34896433 More...
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|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
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|
| G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
decreases export
|
ISO
|
KEAP1 protein results in decreased export of bisbenzimide ethoxide trihydrochloride
|
CTD |
PMID:25841332 |
|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
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|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
multiple interactions
|
ISO
|
[MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride
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CTD |
PMID:19239227 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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|
|
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| G
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Bcl2l1
|
Bcl2-like 1
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in decreased expression of BCL2L1 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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| G
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Ccl4
|
C-C motif chemokine ligand 4
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CCL4 mRNA
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CTD |
PMID:21034357 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
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| G
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Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A protein
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CTD |
PMID:21034357 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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| G
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Cntf
|
ciliary neurotrophic factor
|
multiple interactions
|
ISO
|
2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]]; 2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]
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CTD |
PMID:19635391 |
|
NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488
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| G
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Cryab
|
crystallin, alpha B
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CRYAB mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
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| G
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Cxcl10
|
C-X-C motif chemokine ligand 10
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CXCL10 mRNA
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CTD |
PMID:21034357 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
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| G
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Egr1
|
early growth response 1
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EGR1 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
|
|
| G
|
Ephx2
|
epoxide hydrolase 2
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EPHX2 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
|
|
| G
|
Faslg
|
Fas ligand
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of FASLG mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GADD45A mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Gdf15
|
growth differentiation factor 15
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
| G
|
Gstm5
|
glutathione S-transferase, mu 5
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GSTM3 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 protein
|
CTD |
PMID:21034357 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A protein
|
CTD |
PMID:21034357 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
|
|
| G
|
Hspa2
|
heat shock protein family A (Hsp70) member 2
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA2 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133
|
|
| G
|
Hspa6l-ps1
|
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 protein
|
CTD |
PMID:21034357 |
|
NCBI chr13:85,805,911...85,807,052
|
|
| G
|
Lta
|
lymphotoxin alpha
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of LTA mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of NOS2 mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions increases reduction increases response to substance
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in decreased expression of BCL2L1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CCL4 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CRYAB mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CXCL10 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EGR1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EPHX2 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of FASLG mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GADD45A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GSTM3 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA2 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of LTA mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of NOS2 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of TNF mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased phosphorylation of TP53 protein; Carbamazepine inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; Diclofenac inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; Dicumarol inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; Mefenamic Acid inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; NQO1 protein inhibits the reaction [2,6-Dichloroindophenol results in decreased abundance of Glutathione]; NQO1 protein polymorphism promotes the reaction [2,6-Dichloroindophenol results in decreased abundance of Glutathione]; Tacrine inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol] NQO1 protein polymorphism results in increased susceptibility to 2,6-Dichloroindophenol
|
CTD |
PMID:21034357 PMID:29281794 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Nqo2
|
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
|
multiple interactions increases reduction
|
ISO
|
[NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of 2,6-Dichloroindophenol; [NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of 2,6-Dichloroindophenol; resveratrol inhibits the reaction [NQO2 protein results in increased reduction of 2,6-Dichloroindophenol]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of 2,6-Dichloroindophenol]
|
CTD |
PMID:20399199 PMID:29281794 |
|
NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662
|
|
| G
|
Stat1
|
signal transducer and activator of transcription 1
|
multiple interactions
|
ISO
|
2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]]
|
CTD |
PMID:19635391 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Stat3
|
signal transducer and activator of transcription 3
|
multiple interactions
|
ISO
|
2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]
|
CTD |
PMID:19635391 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of TNF mRNA
|
CTD |
PMID:21034357 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased phosphorylation of TP53 protein
|
CTD |
PMID:21034357 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
|
|
| G
|
Abcb1b
|
ATP-binding cassette, sub-family B member 1B
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of ABCB1B mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567
|
|
| G
|
Acmsd
|
aminocarboxymuconate semialdehyde decarboxylase
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of ACMSD mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr13:41,752,894...41,798,427
Ensembl chr13:41,752,875...41,798,427
|
|
| G
|
Acsl3
|
acyl-CoA synthetase long-chain family member 3
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of ACSL3 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:87,563,601...87,613,097
|
|
| G
|
Aen
|
apoptosis enhancing nuclease
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of AEN mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898
|
|
| G
|
Akr7a3
|
aldo-keto reductase family 7 member A3
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of AKR7A3 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of ALDH1A1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Apoa2
|
apolipoprotein A2
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of APOA2 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410
|
|
| G
|
Apoa4
|
apolipoprotein A4
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of APOA4 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
|
|
| G
|
Apoc3
|
apolipoprotein C3
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of APOC3 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679
|
|
| G
|
Atp6v1d
|
ATPase H+ transporting V1 subunit D
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of ATP6V1D mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of BAX mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of BTG2 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
C7
|
complement C7
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of C7 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
|
|
| G
|
Cblc
|
Cbl proto-oncogene C
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of CBLC mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709
|
|
| G
|
Ccng1
|
cyclin G1
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of CCNG1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
|
|
| G
|
Cd276
|
Cd276 molecule
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of CD276 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 8:67,833,587...67,863,918
Ensembl chr 8:67,829,048...67,864,505
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of CDKN1A mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cpq
|
carboxypeptidase Q
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of CPQ mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
|
|
| G
|
Cryab
|
crystallin, alpha B
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of CRYAB mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
|
|
| G
|
Cyp2c13
|
cytochrome P450, family 2, subfamily c, polypeptide 13
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of CYP2C13 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210
|
|
| G
|
Cyp4f5
|
cytochrome P450, family 4, subfamily f, polypeptide 5
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of CYP4F5 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 7:12,194,567...12,209,495
Ensembl chr 7:12,195,022...12,209,965
|
|
| G
|
Ddah1
|
dimethylarginine dimethylaminohydrolase 1
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of DDAH1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626
|
|
| G
|
Epcam
|
epithelial cell adhesion molecule
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of EPCAM mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of EPHX1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Fas
|
Fas cell surface death receptor
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of FAS mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
| G
|
Fhit
|
fragile histidine triad diadenosine triphosphatase
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of FHIT mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr15:16,365,401...17,872,901
Ensembl chr15:16,747,338...17,872,621
|
|
| G
|
Gria3
|
glutamate ionotropic receptor AMPA type subunit 3
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of GRIA3 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679
|
|
| G
|
Gstm1
|
glutathione S-transferase mu 1
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of GSTM1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
|
|
| G
|
Hsd17b6
|
hydroxysteroid (17-beta) dehydrogenase 6
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of HSD17B6 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873
|
|
| G
|
Il2ra
|
interleukin 2 receptor subunit alpha
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of IL2RA mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of MGMT mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Nupr1
|
nuclear protein 1, transcriptional regulator
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of NUPR1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901
|
|
| G
|
Or2at1
|
olfactory receptor family 2 subfamily AT member 1
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of OR2AT1 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr 1:163,501,335...163,502,300
Ensembl chr 1:163,501,335...163,502,300
|
|
| G
|
Pbsn
|
probasin
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of PBSN mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr X:45,792,738...45,807,983
Ensembl chr X:45,792,738...45,807,983
|
|
| G
|
Phlda3
|
pleckstrin homology-like domain, family A, member 3
|
decreases expression
|
EXP
|
2-nitro-4-phenylenediamine results in decreased expression of PHLDA3 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621
|
|
| G
|
Rhobtb2
|
Rho-related BTB domain containing 2
|
increases expression
|
EXP
|
2-nitro-4-phenylenediamine results in increased expression of RHOBTB2 mRNA
|
CTD |
PMID:17070881 |
|
NCBI chr15:51,278,024...51,298,209
Ensembl chr15:51,280,149...51,298,209
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Serpina7
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serpin family A member 7
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increases expression
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EXP
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2-nitro-4-phenylenediamine results in increased expression of SERPINA7 mRNA
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CTD |
PMID:17070881 |
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NCBI chr X:107,452,044...107,510,958
Ensembl chr X:107,452,044...107,457,681
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Slc16a10
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solute carrier family 16 member 10
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decreases expression
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EXP
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2-nitro-4-phenylenediamine results in decreased expression of SLC16A10 mRNA
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CTD |
PMID:17070881 |
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NCBI chr20:45,014,229...45,122,392
Ensembl chr20:45,014,235...45,122,358
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Spink1
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serine peptidase inhibitor, Kazal type 1
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decreases expression
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EXP
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2-nitro-4-phenylenediamine results in decreased expression of SPINK1 mRNA
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CTD |
PMID:17070881 |
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NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545
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Sugct
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succinylCoA:glutarate-CoA transferase
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increases expression
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EXP
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2-nitro-4-phenylenediamine results in increased expression of SUGCT mRNA
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CTD |
PMID:17070881 |
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NCBI chr17:52,072,012...52,929,852
Ensembl chr17:52,072,052...52,930,281
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Sulf2
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sulfatase 2
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decreases expression
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EXP
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2-nitro-4-phenylenediamine results in decreased expression of SULF2 mRNA
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CTD |
PMID:17070881 |
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NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651
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Sult2a1
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sulfotransferase family 2A member 1
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increases expression
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EXP
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2-nitro-4-phenylenediamine results in increased expression of SULT2A1 mRNA
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CTD |
PMID:17070881 |
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NCBI chr 1:84,582,011...84,639,001
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Zmat3
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zinc finger, matrin type 3
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decreases expression
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EXP
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2-nitro-4-phenylenediamine results in decreased expression of ZMAT3 mRNA
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CTD |
PMID:17070881 |
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NCBI chr 2:117,034,517...117,066,141
Ensembl chr 2:117,034,517...117,065,294
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Ddit3
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DNA-damage inducible transcript 3
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affects expression
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ISO
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3,4-dihydrocoumarin affects the expression of DDIT3 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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| G
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Dnaja2
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DnaJ heat shock protein family (Hsp40) member A2
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of DNAJA2 mRNA
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CTD |
PMID:22016648 |
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NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120
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| G
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Egf
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epidermal growth factor
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increases expression
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ISO
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3,4-dihydrocoumarin results in increased expression of EGF mRNA
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CTD |
PMID:22016648 |
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NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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Ephx1
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epoxide hydrolase 1
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of EPHX1 mRNA
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CTD |
PMID:22016648 |
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NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
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Hsd17b4
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hydroxysteroid (17-beta) dehydrogenase 4
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increases expression
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ISO
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3,4-dihydrocoumarin results in increased expression of HSD17B4 mRNA
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CTD |
PMID:22016648 |
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NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
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Hsp90ab1
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heat shock protein 90 alpha family class B member 1
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of HSP90AB1 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
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Hspa1a
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heat shock protein family A (Hsp70) member 1A
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increases expression
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ISO
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3,4-dihydrocoumarin results in increased expression of HSPA1A mRNA
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CTD |
PMID:22016648 |
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NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
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Kap
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kidney androgen regulated protein
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of KAP mRNA
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CTD |
PMID:22016648 |
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NCBI chr 4:168,405,981...168,409,032
Ensembl chr 4:168,405,988...168,409,032
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Oat
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ornithine aminotransferase
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of OAT mRNA
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CTD |
PMID:22016648 |
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NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
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Pck1
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phosphoenolpyruvate carboxykinase 1
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of PCK1 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
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Pon1
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paraoxonase 1
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affects metabolic processing
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ISO
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PON1 SNP affects the metabolism of 3,4-dihydrocoumarin
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CTD |
PMID:25027835 |
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NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924
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Prdx1
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peroxiredoxin 1
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increases expression
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ISO
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3,4-dihydrocoumarin results in increased expression of PRDX1 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
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Prdx3
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peroxiredoxin 3
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of PRDX3 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300
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Psmb8
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proteasome 20S subunit beta 8
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of PSMB8 mRNA
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CTD |
PMID:22016648 |
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NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031
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Ptpmt1
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protein tyrosine phosphatase, mitochondrial 1
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of PTPMT1 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 3:97,345,752...97,355,396
Ensembl chr 3:97,345,752...97,355,254
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Rbp4
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retinol binding protein 4
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of RBP4 mRNA
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CTD |
PMID:22016648 |
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NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898
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Sod1
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superoxide dismutase 1
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of SOD1 mRNA
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CTD |
PMID:22016648 |
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NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
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Timp2
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TIMP metallopeptidase inhibitor 2
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of TIMP2 mRNA
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CTD |
PMID:22016648 |
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NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
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| G
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Tubb5
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tubulin, beta 5 class I
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decreases expression
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ISO
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3,4-dihydrocoumarin results in decreased expression of TUBB5 mRNA
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CTD |
PMID:22016648 |
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NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726
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Alb
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albumin
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affects binding
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ISO
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Alizarin Red S binds to ALB protein
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CTD |
PMID:18968587 |
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NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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Abcb1a
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ATP binding cassette subfamily B member 1A
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decreases activity
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ISO
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thiazolyl blue results in decreased activity of ABCB1 protein
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CTD |
PMID:15451006 |
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NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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| G
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Aco2
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aconitase 2
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multiple interactions
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ISO
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[Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue
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CTD |
PMID:12548706 |
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NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
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Casp3
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caspase 3
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increases activity
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ISO
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thiazolyl blue results in increased activity of CASP3 protein
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CTD |
PMID:22401948 |
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp8
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caspase 8
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increases activity
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ISO
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thiazolyl blue results in increased activity of CASP8 protein
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CTD |
PMID:22401948 |
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NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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| G
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Nqo2
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N-ribosyldihydronicotinamide:quinone dehydrogenase 2
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increases reduction multiple interactions
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ISO
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NQO2 protein results in increased reduction of thiazolyl blue resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
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CTD |
PMID:29281794 |
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NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662
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Akt1
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AKT serine/threonine kinase 1
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of AKT1 protein]
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CTD |
PMID:36828244 |
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NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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| G
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Dnmt1
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DNA methyltransferase 1
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decreases activity
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ISO
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lac dye results in decreased activity of DNMT1 protein
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CTD |
PMID:23839987 |
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NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
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| G
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Ezh2
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enhancer of zeste 2 polycomb repressive complex 2 subunit
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in decreased expression of EZH2 mRNA]
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CTD |
PMID:36828244 |
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NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
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| G
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Foxo1
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forkhead box O1
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of and results in decreased phosphorylation of FOXO1 protein]; lac dye inhibits the reaction [Dietary Fats results in increased expression of FOXO1 mRNA]
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CTD |
PMID:36828244 |
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NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
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| G
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G6pc1
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glucose-6-phosphatase catalytic subunit 1
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of G6PC1 mRNA]
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CTD |
PMID:36828244 |
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NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
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| G
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Gpt
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glutamic--pyruvic transaminase
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of GPT protein]
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CTD |
PMID:36828244 |
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NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
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| G
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Gsk3b
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glycogen synthase kinase 3 beta
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of GSK3B protein]
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CTD |
PMID:36828244 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
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Il1b
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interleukin 1 beta
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of IL1B mRNA]
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CTD |
PMID:36828244 |
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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| G
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Il6
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interleukin 6
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of IL6 mRNA]
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CTD |
PMID:36828244 |
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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| G
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Ins1
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insulin 1
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]
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CTD |
PMID:36828244 |
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
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| G
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Mapk1
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mitogen activated protein kinase 1
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK1 protein]
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CTD |
PMID:36828244 |
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NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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| G
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Mapk3
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mitogen activated protein kinase 3
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK3 protein]
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CTD |
PMID:36828244 |
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NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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| G
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Pck1
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phosphoenolpyruvate carboxykinase 1
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]
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CTD |
PMID:36828244 |
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NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
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| G
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Rela
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RELA proto-oncogene, NF-kB subunit
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased phosphorylation of RELA protein]
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CTD |
PMID:36828244 |
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NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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| G
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Tnf
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tumor necrosis factor
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multiple interactions
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ISO
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lac dye inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]
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CTD |
PMID:36828244 |
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Abcc2
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ATP binding cassette subfamily C member 2
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affects transport multiple interactions increases export increases transport
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EXP ISO
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ABCC2 protein affects the transport of 5(6)-carboxy-2',7'-dichlorofluorescein 4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Tobacco Smoke Pollution inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog] ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog [ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 gene mutant form inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]
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CTD |
PMID:19326901 PMID:21240898 PMID:21341280 PMID:23562342 PMID:24907646 PMID:24909372 PMID:24973091 PMID:25862123 PMID:27450509 PMID:31348918 More...
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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| G
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Abcc3
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ATP binding cassette subfamily C member 3
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multiple interactions increases transport
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EXP ISO
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[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
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CTD |
PMID:24907646 PMID:31348918 |
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NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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| G
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Abcc5
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ATP binding cassette subfamily C member 5
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multiple interactions increases uptake increases transport
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ISO
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Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] ABCC5 protein results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein
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CTD |
PMID:31348918 PMID:35066093 |
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NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
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| G
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Slc22a8
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solute carrier family 22 member 8
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multiple interactions increases uptake increases transport
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ISO
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Niclosamide inhibits the reaction [SLC22A8 protein results in increased uptake of 4-carboxyfluorescein]; Novobiocin inhibits the reaction [SLC22A8 protein results in increased uptake of 4-carboxyfluorescein]; quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]
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CTD |
PMID:21244849 PMID:38280639 |
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NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
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| G
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Abcc2
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ATP binding cassette subfamily C member 2
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multiple interactions
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ISO
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ABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione]
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CTD |
PMID:16049127 |
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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| G
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Abcc1
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ATP binding cassette subfamily C member 1
|
increases export
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ISO
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ABCC1 protein results in increased export of 6-carboxyfluorescein
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CTD |
PMID:17940500 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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| G
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Abcc2
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ATP binding cassette subfamily C member 2
|
affects export multiple interactions
|
ISO
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ABCC2 protein affects the export of 6-carboxyfluorescein Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]
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CTD |
PMID:11477083 |
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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| G
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Slc22a6
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solute carrier family 22 member 6
|
multiple interactions increases uptake increases import
|
ISO
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2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; 7-hydroxycoumarin inhibits the reaction [SLC22A6 protein results in increased uptake of 6-carboxyfluorescein]; 7-hydroxycoumarin metabolite inhibits the reaction [SLC22A6 protein results in increased uptake of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of 6-carboxyfluorescein]; Unithiol analog inhibits the reaction [SLC22A6 protein results in increased uptake of 6-carboxyfluorescein]
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CTD |
PMID:20237588 PMID:28629854 PMID:39481674 |
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NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311
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| G
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Slc22a8
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solute carrier family 22 member 8
|
increases import increases uptake multiple interactions
|
ISO
|
SLC22A8 protein results in increased import of 6-carboxyfluorescein SLC22A8 protein results in increased uptake of 6-carboxyfluorescein 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine promotes the reaction [2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-9H-pyrido(2,3-b)indole promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 7-hydroxycoumarin glucuronide inhibits the reaction [SLC22A8 protein results in increased uptake of 6-carboxyfluorescein]; 7-hydroxycoumarin inhibits the reaction [SLC22A8 protein results in increased uptake of 6-carboxyfluorescein]; 7-hydroxycoumarin metabolite inhibits the reaction [SLC22A8 protein results in increased uptake of 6-carboxyfluorescein]; Cadmium Chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; lead chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of 6-carboxyfluorescein]; sodium arsenate promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Unithiol analog inhibits the reaction [SLC22A8 protein results in increased uptake of 6-carboxyfluorescein]
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CTD |
PMID:20237588 PMID:28629854 PMID:39481674 |
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NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
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| G
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Ache
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acetylcholinesterase
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affects binding decreases activity
|
ISO
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Aminacrine binds to ACHE protein Aminacrine results in decreased activity of ACHE protein
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CTD |
PMID:31176713 PMID:33844597 |
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NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
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| G
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Bax
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BCL2 associated X, apoptosis regulator
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increases response to substance
|
ISO
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BAX protein results in increased susceptibility to Aminacrine
|
CTD |
PMID:16177561 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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| G
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H2ax
|
H2A.X variant histone
|
decreases phosphorylation multiple interactions
|
ISO
|
Aminacrine results in decreased phosphorylation of H2AX protein [Aminacrine results in decreased phosphorylation of H2AX protein] inhibits the reaction [Camptothecin results in increased activity of and affects the localization of MDC1 protein]
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CTD |
PMID:26928355 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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| G
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Hif1a
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hypoxia inducible factor 1 subunit alpha
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increases activity
|
ISO
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Aminacrine results in increased activity of HIF1A protein
|
CTD |
PMID:19502547 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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| G
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Mdc1
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mediator of DNA damage checkpoint 1
|
multiple interactions
|
ISO
|
[Aminacrine results in decreased phosphorylation of H2AX protein] inhibits the reaction [Camptothecin results in increased activity of and affects the localization of MDC1 protein]; Aminacrine inhibits the reaction [Camptothecin results in increased activity of and affects the localization of MDC1 protein]
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CTD |
PMID:26928355 |
|
NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960
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| G
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Nr1h4
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nuclear receptor subfamily 1, group H, member 4
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multiple interactions
|
ISO
|
Aminacrine inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
|
CTD |
PMID:25257666 |
|
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
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| G
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Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Aminacrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
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| G
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Tp53
|
tumor protein p53
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multiple interactions affects activity
|
ISO
|
Aminacrine results in increased stability of and results in increased activity of TP53 protein Aminacrine analog affects the activity of TP53 protein
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CTD |
PMID:16177561 PMID:35435491 |
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NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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| G
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Alb
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albumin
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affects binding
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ISO
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chromotrope 2R binds to ALB protein
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CTD |
PMID:19347248 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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| G
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Bax
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BCL2 associated X, apoptosis regulator
|
increases response to substance
|
ISO
|
BAX protein results in increased susceptibility to Acridine Orange
|
CTD |
PMID:16177561 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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| G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
[Acridine Orange binds to Platinum Compounds] which results in increased expression of GSTP1 mRNA; [Acridine Orange binds to Platinum] which results in increased expression of GSTP1 mRNA
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CTD |
PMID:16814760 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
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| G
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Tp53
|
tumor protein p53
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multiple interactions
|
ISO
|
Acridine Orange results in increased stability of and results in increased activity of TP53 protein
|
CTD |
PMID:16177561 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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|
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| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases response to substance
|
ISO
|
BAX protein results in increased susceptibility to Acridine Orange
|
CTD |
PMID:16177561 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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| G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
[Acridine Orange binds to Platinum Compounds] which results in increased expression of GSTP1 mRNA; [Acridine Orange binds to Platinum] which results in increased expression of GSTP1 mRNA
|
CTD |
PMID:16814760 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
Acridine Orange results in increased stability of and results in increased activity of TP53 protein
|
CTD |
PMID:16177561 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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| G
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Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
decreases activity multiple interactions
|
ISO
|
alizarin results in decreased activity of CYP1A1 protein alizarin affects the reaction [Benzo(a)pyrene affects the activity of CYP1A1 protein]
|
CTD |
PMID:12379470 PMID:37515497 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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| G
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Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases activity
|
ISO
|
alizarin results in decreased activity of CYP1A2 protein
|
CTD |
PMID:12379470 PMID:33438235 |
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NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
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| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
decreases activity
|
ISO
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alizarin results in decreased activity of CYP1B1 protein
|
CTD |
PMID:12379470 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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| G
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Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
decreases activity
|
ISO
|
alizarin results in decreased activity of CYP2E1 protein
|
CTD |
PMID:12379470 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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| G
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Esr1
|
estrogen receptor 1
|
multiple interactions
|
ISO
|
alizarin binds to and results in increased activity of ESR1 protein
|
CTD |
PMID:20707409 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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| G
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H2ax
|
H2A.X variant histone
|
multiple interactions
|
ISO
|
alizarin inhibits the reaction [Benzo(a)pyrene results in increased expression of H2AX protein]
|
CTD |
PMID:37515497 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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| G
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Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
ISO EXP
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alizarin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; alizarin inhibits the reaction [Indican results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:33421718 PMID:38670245 |
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NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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| G
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Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
ISO
|
alizarin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:33421718 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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| G
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Muc5ac
|
mucin 5AC, oligomeric mucus/gel-forming
|
multiple interactions
|
ISO
|
alizarin inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC mRNA]; alizarin inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein]
|
CTD |
PMID:33421718 |
|
NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
|
|
| G
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Nat1
|
N-acetyltransferase 1
|
decreases activity
|
ISO
|
alizarin results in decreased activity of NAT1 protein
|
CTD |
PMID:34783865 |
|
NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
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| G
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Ugt1a1
|
UDP glucuronosyltransferase family 1 member A1
|
increases glucuronidation
|
ISO
|
UGT1A1 protein results in increased glucuronidation of alizarin
|
CTD |
PMID:14557274 |
|
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
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| G
|
Ugt1a9
|
UDP glucuronosyltransferase family 1 member A9
|
increases glucuronidation
|
ISO
|
UGT1A9 protein results in increased glucuronidation of alizarin
|
CTD |
PMID:14557274 |
|
NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
| G
|
Ugt2b15
|
UDP glucuronosyltransferase family 2 member B15
|
increases metabolic processing
|
EXP
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UGT2B15 protein results in increased metabolism of alizarin
|
CTD |
PMID:7574722 |
|
NCBI chr14:21,122,866...21,138,450
Ensembl chr14:21,122,861...21,138,467
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|
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| G
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Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
multiple interactions increases expression
|
ISO
|
ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein] Benzophenoneidum results in increased expression of ALDH1A1 protein
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CTD |
PMID:28722353 |
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NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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| G
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Ano6
|
anoctamin 6
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of ANO6 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 7:128,812,842...128,992,805
Ensembl chr 7:128,813,068...128,992,799
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| G
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Araf
|
A-Raf proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of ARAF protein
|
CTD |
PMID:28722353 |
|
NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611
|
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| G
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Atp6ap2
|
ATPase H+ transporting accessory protein 2
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of ATP6AP2 protein
|
CTD |
PMID:28722353 |
|
NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875
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| G
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Ccdc22
|
coiled-coil domain containing 22
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of CCDC22 protein
|
CTD |
PMID:28722353 |
|
NCBI chr X:17,570,184...17,582,130
Ensembl chr X:17,535,659...17,582,130
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|
| G
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Ccdc39
|
coiled-coil domain 39 molecular ruler complex subunit
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of CCDC39 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 2:118,593,881...118,631,584
Ensembl chr 2:118,593,881...118,631,647
|
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| G
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Cd44
|
CD44 molecule
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of CD44 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
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| G
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Chtf18
|
chromosome transmission fidelity factor 18
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of CHTF18 protein
|
CTD |
PMID:28722353 |
|
NCBI chr10:15,247,525...15,255,573
Ensembl chr10:15,246,362...15,255,685
|
|
| G
|
Commd1
|
copper metabolism domain containing 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of COMMD1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr14:101,081,667...101,185,738
Ensembl chr14:101,081,667...101,185,639
|
|
| G
|
Cops7b
|
COP9 signalosome subunit 7B
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of COPS7B protein
|
CTD |
PMID:28722353 |
|
NCBI chr 9:94,686,314...94,711,903
Ensembl chr 9:94,686,314...94,711,903
|
|
| G
|
Cul3
|
cullin 3
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of CUL3 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:89,040,987...89,118,427
|
|
| G
|
Dynlt1
|
dynein light chain Tctex-type 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of DYNLT1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 1:49,292,093...49,299,051
Ensembl chr 1:49,282,243...49,298,951
|
|
| G
|
Eif4g3
|
eukaryotic translation initiation factor 4 gamma, 3
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of EIF4G3 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 5:155,481,378...155,702,194
Ensembl chr 5:155,481,378...155,702,194
|
|
| G
|
Fastkd2
|
FAST kinase domains 2
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of FASTKD2 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 9:72,659,961...72,681,986
Ensembl chr 9:72,661,764...72,721,338
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases phosphorylation
|
EXP
|
Benzophenoneidum results in increased phosphorylation of H2AX protein
|
CTD |
PMID:37527026 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Hook3
|
hook microtubule-tethering protein 3
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of HOOK3 protein
|
CTD |
PMID:28722353 |
|
NCBI chr16:72,656,929...72,751,696
Ensembl chr16:72,657,019...72,764,071
|
|
| G
|
Hsd17b7
|
hydroxysteroid (17-beta) dehydrogenase 7
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of HSD17B7 protein
|
CTD |
PMID:28722353 |
|
NCBI chr13:84,702,875...84,722,810
Ensembl chr13:84,705,631...84,722,754
|
|
| G
|
Htt
|
huntingtin
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of HTT protein
|
CTD |
PMID:28722353 |
|
NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668
|
|
| G
|
Iqgap3
|
IQ motif containing GTPase activating protein 3
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of IQGAP3 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797
|
|
| G
|
Kifap3
|
kinesin-associated protein 3
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of KIFAP3 protein
|
CTD |
PMID:28722353 |
|
NCBI chr13:78,660,849...78,797,821
Ensembl chr13:78,660,871...78,797,820
|
|
| G
|
Map1lc3b
|
microtubule-associated protein 1 light chain 3 beta
|
multiple interactions
|
ISO
|
ALDH1A1 protein promotes the reaction [Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein]; Benzophenoneidum results in increased lipidation of and results in increased cleavage of MAP1LC3B protein
|
CTD |
PMID:28722353 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
|
|
| G
|
Map2k4
|
mitogen activated protein kinase kinase 4
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of MAP2K4 protein
|
CTD |
PMID:28722353 |
|
NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185
|
|
| G
|
Mbd3
|
methyl-CpG binding domain protein 3
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of MBD3 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 7:9,961,053...9,970,845
Ensembl chr 7:9,963,797...9,970,265
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
increases expression
|
EXP
|
Benzophenoneidum results in increased expression of MKI67 protein
|
CTD |
PMID:37527026 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Noa1
|
nitric oxide associated 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of NOA1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr14:31,189,570...31,205,600
Ensembl chr14:31,188,978...31,205,599
|
|
| G
|
Nup62
|
nucleoporin 62
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of NUP62 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710
|
|
| G
|
Plcg1
|
phospholipase C, gamma 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of PLCG1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050
|
|
| G
|
Ppp4r1
|
protein phosphatase 4, regulatory subunit 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of PPP4R1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 9:112,836,950...112,897,490
Ensembl chr 9:112,838,812...112,897,557
|
|
| G
|
Prim2
|
DNA primase subunit 2
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of PRIM2 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 9:43,188,350...43,400,482
Ensembl chr 9:43,188,350...43,398,990
|
|
| G
|
Prom1
|
prominin 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of PROM1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002
|
|
| G
|
Prorp
|
protein only RNase P catalytic subunit
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of PRORP protein
|
CTD |
PMID:28722353 |
|
NCBI chr 6:78,404,821...78,497,562
Ensembl chr 6:78,405,980...78,497,761
|
|
| G
|
Shmt1
|
serine hydroxymethyltransferase 1
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of SHMT1 protein
|
CTD |
PMID:28722353 |
|
NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,960,434...45,997,326
|
|
| G
|
Srsf11
|
serine and arginine rich splicing factor 11
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of SRSF11 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499
|
|
| G
|
Tbc1d15
|
TBC1 domain family, member 15
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of TBC1D15 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303
|
|
| G
|
Tfam
|
transcription factor A, mitochondrial
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of TFAM protein
|
CTD |
PMID:28722353 |
|
NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
|
|
| G
|
Usp24
|
ubiquitin specific peptidase 24
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of USP24 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 5:126,309,396...126,439,147
Ensembl chr 5:126,309,597...126,439,135
|
|
| G
|
Washc5
|
WASH complex subunit 5
|
increases expression
|
ISO
|
Benzophenoneidum results in increased expression of WASHC5 protein
|
CTD |
PMID:28722353 |
|
NCBI chr 7:92,773,625...92,825,532
Ensembl chr 7:92,773,625...92,825,532
|
|
|
|
| G
|
Lig1
|
DNA ligase 1
|
decreases activity
|
ISO
|
Aurintricarboxylic Acid results in decreased activity of LIG1 protein
|
CTD |
PMID:15134906 |
|
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
|
|
| G
|
Ogg1
|
8-oxoguanine DNA glycosylase
|
decreases activity
|
ISO
|
Aurintricarboxylic Acid results in decreased activity of OGG1 protein
|
CTD |
PMID:26218629 |
|
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
|
|
|
|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
increases activity
|
EXP
|
Azure A results in increased activity of GPT protein
|
CTD |
PMID:33775737 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
|
|
| G
|
App
|
amyloid beta precursor protein
|
multiple interactions
|
ISO
|
[Azure B affects the cleavage of APP protein] which results in decreased secretion of APP protein modified form; Azure B results in decreased expression of and affects the cleavage of APP protein
|
CTD |
PMID:30500345 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Bace1
|
beta-secretase 1
|
decreases activity
|
ISO
|
Azure B results in decreased activity of BACE1 protein
|
CTD |
PMID:30500345 |
|
NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918
|
|
|
|
| G
|
Akr1b1
|
aldo-keto reductase family 1 member B1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of AKR1B1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
|
|
| G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of AKR1B10 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of AKR1C1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of AKR1C3 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
|
|
| G
|
Cat
|
catalase
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of CAT mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccl17
|
C-C motif chemokine ligand 17
|
affects expression
|
ISO
|
Bandrowski's base affects the expression of CCL17 mRNA
|
CTD |
PMID:18202158 |
|
NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895
|
|
| G
|
Ccl22
|
C-C motif chemokine ligand 22
|
affects expression
|
ISO
|
Bandrowski's base affects the expression of CCL22 mRNA
|
CTD |
PMID:18202158 |
|
NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
affects expression
|
ISO
|
Bandrowski's base affects the expression of CCL4 mRNA
|
CTD |
PMID:18202158 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccr7
|
C-C motif chemokine receptor 7
|
affects expression increases expression
|
ISO
|
Bandrowski's base affects the expression of CCR7 mRNA Bandrowski's base results in increased expression of CCR7 protein
|
CTD |
PMID:18202158 PMID:19665512 |
|
NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501
|
|
| G
|
Cd80
|
Cd80 molecule
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of CD80 protein
|
CTD |
PMID:31958493 |
|
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
|
|
| G
|
Cd86
|
CD86 molecule
|
affects expression increases expression multiple interactions
|
ISO
|
Bandrowski's base affects the expression of CD86 mRNA Bandrowski's base results in increased expression of CD86 protein MIR146A affects the reaction [Bandrowski's base results in increased expression of CD86 protein]; PRKCB protein affects the reaction [Bandrowski's base results in increased expression of CD86 protein]
|
CTD |
PMID:18202158 PMID:19665512 PMID:21742781 PMID:31958493 PMID:37326882 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
affects expression
|
ISO
|
Bandrowski's base affects the expression of CXCR4 mRNA
|
CTD |
PMID:18202158 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Fech
|
ferrochelatase
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of FECH mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546
|
|
| G
|
Ftl1
|
ferritin light chain 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of FTL mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915 Ensembl chr 2:45,399,355...45,399,915 Ensembl chr 1:45,399,355...45,399,915
|
|
| G
|
G6pd
|
glucose-6-phosphate dehydrogenase
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of G6PD mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of GCLC mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of GCLM mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
|
|
| G
|
Gpx3
|
glutathione peroxidase 3
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of GPX3 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of GSR mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of HMOX1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
increases expression affects expression
|
ISO
|
Bandrowski's base results in increased expression of ICAM1 protein Bandrowski's base affects the expression of ICAM1 mRNA
|
CTD |
PMID:18202158 PMID:21742781 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
|
Maff
|
MAF bZIP transcription factor F
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of MAFF mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147
|
|
| G
|
Mafg
|
MAF bZIP transcription factor G
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of MAFG mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr10:106,401,633...106,410,159
|
|
| G
|
Mafk
|
MAF bZIP transcription factor K
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of MAFK mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192
|
|
| G
|
Me1
|
malic enzyme 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of ME1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
|
|
| G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of MGST1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
|
|
| G
|
Mir146a
|
microRNA 146a
|
multiple interactions
|
ISO
|
MIR146A affects the reaction [Bandrowski's base results in increased expression of CD86 protein]
|
CTD |
PMID:37326882 |
|
NCBI chr10:28,349,996...28,350,090
|
|
| G
|
Mir155
|
microRNA 155
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of MIR155 mRNA
|
CTD |
PMID:32939143 |
|
NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178
|
|
| G
|
Mir21
|
microRNA 21
|
decreases expression
|
ISO
|
Bandrowski's base results in decreased expression of MIR21 mRNA
|
CTD |
PMID:32939143 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of NQO1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Pgd
|
phosphogluconate dehydrogenase
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of PGD mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
|
|
| G
|
Ppia
|
peptidylprolyl isomerase A
|
affects expression
|
ISO
|
Bandrowski's base affects the expression of PPIA mRNA
|
CTD |
PMID:18202158 |
|
NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115
|
|
| G
|
Prkcb
|
protein kinase C, beta
|
increases expression multiple interactions
|
ISO
|
Bandrowski's base results in increased expression of PRKCB protein PRKCB protein affects the reaction [Bandrowski's base results in increased expression of CD86 protein]
|
CTD |
PMID:31958493 PMID:37326882 |
|
NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740
|
|
| G
|
Ptgr1
|
prostaglandin reductase 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of PTGR1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of SOD1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of SOD2 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Sod3
|
superoxide dismutase 3
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of SOD3 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
|
|
| G
|
Srxn1
|
sulfiredoxin 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of SRXN1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
|
|
| G
|
Tnfrsf1a
|
TNF receptor superfamily member 1A
|
affects expression
|
ISO
|
Bandrowski's base affects the expression of TNFRSF1A mRNA
|
CTD |
PMID:18202158 |
|
NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816
|
|
| G
|
Txn2
|
thioredoxin 2
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of TXN2 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:111,386,805...111,390,022
|
|
| G
|
Txnrd1
|
thioredoxin reductase 1
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of TXNRD1 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
|
|
| G
|
Txnrd2
|
thioredoxin reductase 2
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of TXNRD2 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475
|
|
| G
|
Ugt1a6a
|
UDP glucuronosyltransferase family 1 member A6a
|
increases expression
|
ISO
|
Bandrowski's base results in increased expression of UGT1A6 mRNA
|
CTD |
PMID:20566472 |
|
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
|
|
| G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
brazilein results in decreased expression of CCND1 mRNA; brazilein results in decreased expression of CCND1 protein
|
CTD |
PMID:23948132 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
decreases expression
|
ISO
|
brazilein results in decreased expression of CTNNB1 protein
|
CTD |
PMID:23948132 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
decreases expression
|
ISO
|
brazilein results in decreased expression of GSK3B protein modified form
|
CTD |
PMID:23948132 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
multiple interactions decreases expression
|
ISO
|
brazilein promotes the reaction [SB 203580 results in decreased expression of and results in decreased activity of MMP2 protein]; brazilein promotes the reaction [wortmannin results in decreased expression of and results in decreased activity of MMP2 protein]; brazilein results in decreased expression of and results in decreased activity of MMP2 protein; SB 203580 promotes the reaction [brazilein results in decreased expression of and results in decreased activity of MMP2 protein]; wortmannin promotes the reaction [brazilein results in decreased expression of and results in decreased activity of MMP2 protein] brazilein results in decreased expression of MMP2 mRNA
|
CTD |
PMID:23707804 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions
|
ISO
|
brazilein results in decreased expression of and results in decreased phosphorylation of NFKBIA protein
|
CTD |
PMID:23707804 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
decreases expression
|
ISO
|
brazilein results in decreased expression of RELA protein
|
CTD |
PMID:23707804 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression
|
ISO
|
brazilin results in increased expression of BAX protein
|
CTD |
PMID:28063998 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
ISO
|
brazilin results in decreased expression of BCL2 protein
|
CTD |
PMID:28063998 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Becn1
|
beclin 1
|
multiple interactions increases expression
|
ISO
|
Acetylcysteine inhibits the reaction [brazilin results in increased expression of BECN1 protein]; BECN1 inhibits the reaction [brazilin results in increased activity of CASP3 protein]; BECN1 inhibits the reaction [brazilin results in increased expression of PARP1 protein modified form]; RELA protein promotes the reaction [brazilin results in increased expression of BECN1 mRNA]; RELA protein promotes the reaction [brazilin results in increased expression of BECN1 protein] brazilin results in increased expression of BECN1 mRNA; brazilin results in increased expression of BECN1 protein
|
CTD |
PMID:28063998 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
|
| G
|
Casp3
|
caspase 3
|
increases activity multiple interactions
|
ISO
|
brazilin results in increased activity of CASP3 protein Acetylcysteine promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; BECN1 inhibits the reaction [brazilin results in increased activity of CASP3 protein]
|
CTD |
PMID:28063998 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions increases expression
|
ISO
|
bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; BECN1 inhibits the reaction [brazilin results in increased expression of PARP1 protein modified form]
|
CTD |
PMID:28063998 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
RELA protein promotes the reaction [brazilin results in decreased expression of SQSTM1 protein]; RELA protein promotes the reaction [brazilin results in increased expression of BECN1 mRNA]; RELA protein promotes the reaction [brazilin results in increased expression of BECN1 protein]
|
CTD |
PMID:28063998 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Sqstm1
|
sequestosome 1
|
decreases expression multiple interactions
|
ISO
|
brazilin results in decreased expression of SQSTM1 protein Acetylcysteine inhibits the reaction [brazilin results in decreased expression of SQSTM1 protein]; RELA protein promotes the reaction [brazilin results in decreased expression of SQSTM1 protein]
|
CTD |
PMID:28063998 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
|
|
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO
|
brilliant green results in increased cleavage of and results in increased activity of CASP3 protein
|
CTD |
PMID:26177467 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Casp7
|
caspase 7
|
multiple interactions
|
ISO
|
brilliant green results in increased cleavage of and results in increased activity of CASP7 protein
|
CTD |
PMID:26177467 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
|
|
| G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
brilliant green results in decreased expression of CCND1 protein
|
CTD |
PMID:26177467 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ikbke
|
inhibitor of nuclear factor kappa B kinase subunit epsilon
|
decreases expression
|
ISO
|
brilliant green results in decreased expression of IKBKE protein
|
CTD |
PMID:26177467 |
|
NCBI chr13:45,264,404...45,290,737
Ensembl chr13:45,264,412...45,289,396
|
|
| G
|
Lonp1
|
lon peptidase 1, mitochondrial
|
increases expression
|
ISO
|
brilliant green results in increased expression of LONP1 mRNA
|
CTD |
PMID:21215310 |
|
NCBI chr 9:1,534,581...1,546,908
Ensembl chr 9:1,534,584...1,547,427
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
brilliant green inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Txn1
|
thioredoxin 1
|
increases oxidation
|
ISO
|
brilliant green results in increased oxidation of TXN protein
|
CTD |
PMID:21215310 |
|
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
|
|
| G
|
Txn2
|
thioredoxin 2
|
decreases expression affects response to substance multiple interactions
|
ISO
|
brilliant green results in decreased expression of TXN2 protein TXN2 protein affects the susceptibility to brilliant green brilliant green results in increased oxidation of and results in increased degradation of TXN2 protein
|
CTD |
PMID:21215310 |
|
NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:111,386,805...111,390,022
|
|
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
Bromcresol Purple binds to and results in decreased activity of NR1I2 protein
|
CTD |
PMID:20869355 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
|
|
| G
|
Iyd
|
iodotyrosine deiodinase
|
multiple interactions
|
ISO
|
Bromphenol Blue inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
|
CTD |
PMID:33352258 |
|
NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386
|
|
|
|
| G
|
Abcb4
|
ATP binding cassette subfamily B member 4
|
affects transport
|
EXP
|
ABCB4 protein affects the transport of Sulfobromophthalein
|
CTD |
PMID:15304119 |
|
NCBI chr 4:26,106,895...26,164,440
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
affects export
|
ISO
|
ABCC2 protein affects the export of Sulfobromophthalein
|
CTD |
PMID:16046661 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Cck
|
cholecystokinin
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased uptake of CCK protein modified form]
|
CTD |
PMID:25106415 |
|
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
|
|
| G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions affects binding
|
ISO EXP
|
Sulfobromophthalein binds to and affects the folding of and affects the activity of GSTA1 protein Sulfobromophthalein binds to [GSTA1 protein co-treated with GSTA1 protein]; Sulfobromophthalein binds to [GSTA3 protein co-treated with GSTA1 protein] Sulfobromophthalein binds to GSTA1 protein
|
CTD |
PMID:3783048 PMID:9826190 PMID:15147239 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
|
|
| G
|
Gsta3
|
glutathione S-transferase alpha 3
|
multiple interactions decreases activity
|
EXP
|
Sulfobromophthalein binds to [GSTA3 protein co-treated with GSTA1 protein] Sulfobromophthalein results in decreased activity of GSTA3 protein
|
CTD |
PMID:3783048 PMID:8968379 |
|
NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654
|
|
| G
|
Gstm2
|
glutathione S-transferase mu 2
|
decreases activity
|
EXP
|
Sulfobromophthalein results in decreased activity of GSTM2 protein
|
CTD |
PMID:8968379 |
|
NCBI chr 2:198,312,179...198,316,962
|
|
| G
|
Hgf
|
hepatocyte growth factor
|
multiple interactions
|
EXP
|
Sulfobromophthalein inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]
|
CTD |
PMID:18031729 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
|
|
| G
|
Ifng
|
interferon gamma
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]
|
CTD |
PMID:11907163 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Il12b
|
interleukin 12B
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]
|
CTD |
PMID:11907163 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
decreases glutathionylation decreases transport
|
ISO
|
KEAP1 protein results in decreased glutathionylation of Sulfobromophthalein KEAP1 protein results in decreased transport of Sulfobromophthalein
|
CTD |
PMID:19246623 |
|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
affects abundance increases transport increases glutathionylation
|
ISO
|
NFE2L2 protein affects the abundance of Sulfobromophthalein NFE2L2 protein results in increased transport of Sulfobromophthalein NFE2L2 protein results in increased glutathionylation of Sulfobromophthalein
|
CTD |
PMID:19246623 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Slc10a1
|
solute carrier family 10 member 1
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLC10A1 protein results in increased uptake of Dehydroepiandrosterone Sulfate]; Sulfobromophthalein inhibits the reaction [SLC10A1 protein results in increased uptake of Taurocholic Acid]; Sulfobromophthalein inhibits the reaction [SLC10A1 protein results in increased uptake of Taurolithocholic Acid]
|
CTD |
PMID:25106415 PMID:34079822 |
|
NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944
|
|
| G
|
Slc10a2
|
solute carrier family 10 member 2
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLC10A2 protein results in increased uptake of Taurocholic Acid]; Sulfobromophthalein inhibits the reaction [SLC10A2 protein results in increased uptake of Taurolithocholic Acid]
|
CTD |
PMID:34079822 |
|
NCBI chr16:91,088,089...91,111,025
Ensembl chr16:91,076,423...91,111,025
|
|
| G
|
Slc10a6
|
solute carrier family 10 member 6
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLC10A6 protein results in increased uptake of Dehydroepiandrosterone Sulfate]; Sulfobromophthalein inhibits the reaction [SLC10A6 protein results in increased uptake of Taurolithocholic Acid]
|
CTD |
PMID:34079822 |
|
NCBI chr14:6,385,348...6,407,532
Ensembl chr14:6,385,537...6,408,894
|
|
| G
|
Slc16a2
|
solute carrier family 16 member 2
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]
|
CTD |
PMID:28119167 |
|
NCBI chr X:72,791,096...72,914,299
Ensembl chr X:72,781,876...72,914,498
|
|
| G
|
Slc19a1
|
solute carrier family 19 member 1
|
multiple interactions decreases activity
|
EXP
|
Sulfobromophthalein inhibits the reaction [SLC19A1 protein affects the transport of Methotrexate] Sulfobromophthalein results in decreased activity of SLC19A1 protein
|
CTD |
PMID:14612385 |
|
NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488
|
|
| G
|
Slc22a19
|
solute carrier family 22, member 19
|
multiple interactions
|
EXP
|
Sulfobromophthalein inhibits the reaction [SLC22A19 protein affects the transport of estrone sulfate]
|
CTD |
PMID:16079298 |
|
NCBI chr 1:214,339,594...214,394,681
Ensembl chr 1:214,339,599...214,394,681
|
|
| G
|
Slc22a6
|
solute carrier family 22 member 6
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
|
CTD |
PMID:11602689 |
|
NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311
|
|
| G
|
Slc22a7
|
solute carrier family 22 member 7
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLC22A7 protein results in increased uptake of Glutarates]
|
CTD |
PMID:12065749 |
|
NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681
|
|
| G
|
Slc22a8
|
solute carrier family 22 member 8
|
multiple interactions
|
EXP
|
Sulfobromophthalein inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
|
CTD |
PMID:10224140 |
|
NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
|
|
| G
|
Slc46a1
|
solute carrier family 46 member 1
|
multiple interactions decreases activity
|
ISO EXP
|
Sulfobromophthalein inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid] Sulfobromophthalein results in decreased activity of SLC46A1 protein
|
CTD |
PMID:17475902 PMID:18174275 |
|
NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
|
|
| G
|
Slco1a1
|
solute carrier organic anion transporter family, member 1a1
|
multiple interactions
|
EXP
|
Sulfobromophthalein inhibits the reaction [SLCO1A1 protein results in increased uptake of perfluorooctanoic acid]
|
CTD |
PMID:19616083 |
|
NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992
|
|
| G
|
Slco1a4
|
solute carrier organic anion transporter family, member 1a4
|
multiple interactions
|
ISO
|
Sulfobromophthalein inhibits the reaction [SLCO1A2 protein results in increased uptake of Quercetin]
|
CTD |
PMID:24947867 |
|
NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816
|
|
| G
|
Slco1b2
|
solute carrier organic anion transporter family member 1B2
|
affects import increases import increases response to substance increases uptake multiple interactions
|
ISO
|
SLCO1B3 protein affects the import of Sulfobromophthalein SLCO1B3 protein results in increased import of Sulfobromophthalein SLCO1B3 protein results in increased susceptibility to Sulfobromophthalein SLCO1B3 protein results in increased uptake of Sulfobromophthalein Apigenin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; Budesonide inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Clarithromycin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Cyclosporine inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; glimepiride affects the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; kaempferol inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; naringenin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; naringin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; Nateglinide inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Pioglitazone affects the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Pravastatin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Quercetin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Rutin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased susceptibility to Okadaic Acid]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased uptake of (5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased uptake of CCK protein modified form]
|
CTD |
PMID:16046661 PMID:17369605 PMID:20171238 PMID:21430235 PMID:21661758 PMID:22394605 PMID:23121773 PMID:25106415 PMID:26134461 More...
|
|
NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083
|
|
| G
|
Slco2b1
|
solute carrier organic anion transporter family, member 2b1
|
decreases activity increases uptake affects import multiple interactions
|
ISO
|
Sulfobromophthalein results in decreased activity of SLCO2B1 protein SLCO2B1 protein results in increased uptake of Sulfobromophthalein SLCO2B1 protein affects the import of Sulfobromophthalein Budesonide inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; Cyclosporine inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; glimepiride inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; Nateglinide inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; Pioglitazone affects the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; Pravastatin inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]; Sulfobromophthalein inhibits the reaction [SLCO2B1 protein results in increased import of estrone sulfate]; Sulfobromophthalein inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]
|
CTD |
PMID:16046661 PMID:21430235 PMID:23121773 PMID:25106415 PMID:27450509 PMID:31364238 More...
|
|
NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279
|
|
|
|
| G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
Bromthymol Blue binds to and results in increased activity of NR1I2 protein
|
CTD |
PMID:20869355 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
|
|
| G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
multiple interactions
|
ISO
|
Bromthymol Blue binds to and results in decreased activity of NR1I3 protein alternative form
|
CTD |
PMID:20869355 |
|
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
|
|
|
|
| G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases activity
|
ISO
|
Dithiazanine results in decreased activity of KCNH2 protein
|
CTD |
PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
increases export multiple interactions increases secretion
|
ISO
|
ABCB1 protein results in increased export of fluorexon Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Clotrimazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Cyclosporine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Ketoconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Miconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Troleandomycin inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon] [carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon; [Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon; Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; desisobutyrylciclesonide inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Mometasone Furoate inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]
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CTD |
PMID:10571255 PMID:12235267 PMID:16442095 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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| G
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Abcc1
|
ATP binding cassette subfamily C member 1
|
affects export increases export increases import affects transport multiple interactions
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ISO
|
ABCC1 protein affects the export of fluorexon ABCC1 protein results in increased export of fluorexon ABCC1 protein results in increased import of fluorexon ABCC1 protein affects the transport of fluorexon [Glycyrrhetinic Acid affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; [Indomethacin affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; [matairesinol affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; [verlukast affects the activity of ABCC1 protein] which results in increased abundance of fluorexon; Mefloquine inhibits the reaction [ABCC1 protein affects the export of fluorexon]; nobiletin promotes the reaction [ABCC1 protein results in increased import of fluorexon]; Quercetin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]; robinetin inhibits the reaction [ABCC1 protein affects the export of fluorexon]; Silymarin inhibits the reaction [ABCC1 protein results in increased export of fluorexon]; verlukast inhibits the reaction [ABCC1 protein affects the export of fluorexon]; verlukast inhibits the reaction [ABCC1 protein results in increased export of fluorexon]; Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon]
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CTD |
PMID:10685512 PMID:15670588 PMID:16004972 PMID:16156793 PMID:18204840 PMID:18955043 PMID:26454883 More...
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|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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| G
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Abcc2
|
ATP binding cassette subfamily C member 2
|
affects export increases abundance multiple interactions affects transport
|
ISO
|
ABCC2 protein affects the export of fluorexon ABCC2 protein alternative form results in increased abundance of fluorexon robinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon] ABCC2 protein affects the transport of fluorexon
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CTD |
PMID:15670588 PMID:15848949 PMID:22027652 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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| G
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Abcc6
|
ATP binding cassette subfamily C member 6
|
affects transport
|
ISO
|
ABCC6 affects the transport of fluorexon
|
CTD |
PMID:14667841 |
|
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
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|
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| G
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Abcb11
|
ATP binding cassette subfamily B member 11
|
affects export multiple interactions
|
ISO
|
ABCB11 protein affects the export of calcein AM ditekiren inhibits the reaction [ABCB11 protein affects the export of calcein AM]
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CTD |
PMID:10617675 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
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| G
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Abcb1a
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ATP binding cassette subfamily B member 1A
|
affects export increases export multiple interactions increases activity increases transport increases secretion
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ISO EXP
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ABCB1 protein affects the export of calcein AM ABCB1 protein results in increased export of calcein AM ABCB1A protein promotes the reaction [Emodin results in increased export of calcein AM] 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [pinostrobin results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; [tectochrysin results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; [Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; ABCB1 protein affects the reaction [Mifepristone results in decreased transport of calcein AM]; ABCB1 protein affects the reaction [zosuquidar trihydrochloride results in decreased transport of calcein AM]; Atorvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; chlorpyrifos-methyl affects the reaction [ABCB1 protein results in increased transport of calcein AM]; Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]; Diazinon inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Diazinon promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Endosulfan inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Endosulfan promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; fenvalerate inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; phosalone inhibits the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; phosalone inhibits the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; propiconazole inhibits the reaction [phosalone inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole promotes the reaction [Endosulfan inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]] calcein AM results in increased activity of ABCB1 protein mutant form
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CTD |
PMID:10617675 PMID:12711602 PMID:15616150 PMID:16121039 PMID:19223659 PMID:19549930 PMID:21321059 PMID:21783720 PMID:29174985 PMID:30217652 PMID:37259354 More...
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|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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| G
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Abcc1
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ATP binding cassette subfamily C member 1
|
increases transport multiple interactions
|
ISO
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ABCC1 protein results in increased transport of calcein AM [ABCC1 protein results in increased susceptibility to Silver Nitrate] which results in decreased export of calcein AM; [ABCC1 protein results in increased susceptibility to Silver] which results in decreased export of calcein AM; [MLN 8237 results in decreased activity of ABCC1 protein] which results in decreased export of calcein AM; [MYC protein results in increased expression of ABCC1 protein] which results in increased export of calcein AM; [verlukast results in decreased activity of ABCC1 protein] which results in decreased export of calcein AM; verlukast inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]; zearalenol metabolite inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]; Zearalenone inhibits the reaction [ABCC1 protein results in increased transport of calcein AM]
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CTD |
PMID:19239227 PMID:19647055 PMID:27376922 PMID:34896433 |
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NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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| G
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Abcc2
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ATP binding cassette subfamily C member 2
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affects transport multiple interactions increases transport increases export
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ISO EXP
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ABCC2 protein affects the transport of calcein AM Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Lovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Simvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] [MYC protein results in increased expression of ABCC2 protein] which results in increased export of calcein AM; Atorvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Lovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; montelukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]; Simvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; verlukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]; verlukast inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; zearalenol inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Zearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
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CTD |
PMID:15210835 PMID:15616150 PMID:19239227 PMID:19647055 PMID:19952419 |
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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| G
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Abcc3
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ATP binding cassette subfamily C member 3
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affects transport multiple interactions increases transport
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ISO
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ABCC3 protein affects the transport of calcein AM Dexamethasone promotes the reaction [ABCC3 protein affects the transport of calcein AM]; Glutathione promotes the reaction [ABCC3 protein affects the transport of calcein AM]; Hydrocortisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]; Prednisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]; verlukast inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]; zearalenol inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]; Zearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]
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CTD |
PMID:15210835 PMID:15979871 PMID:19647055 |
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NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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| G
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Abcc4
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ATP binding cassette subfamily C member 4
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multiple interactions
|
ISO
|
Glutathione promotes the reaction [ABCC4 protein affects the transport of calcein AM]
|
CTD |
PMID:15210835 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
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| G
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Abcc6
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ATP binding cassette subfamily C member 6
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multiple interactions
|
ISO
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Glutathione promotes the reaction [ABCC6 protein affects the transport of calcein AM]
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CTD |
PMID:15210835 |
|
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
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| G
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Myc
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MYC proto-oncogene, bHLH transcription factor
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multiple interactions
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ISO
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[MYC protein results in increased expression of ABCC1 protein] which results in increased export of calcein AM; [MYC protein results in increased expression of ABCC2 protein] which results in increased export of calcein AM
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CTD |
PMID:19239227 |
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NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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| G
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Slco2b1
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solute carrier organic anion transporter family, member 2b1
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multiple interactions increases uptake
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ISO
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Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Capecitabine inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Docetaxel inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Etoposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Irinotecan inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Methotrexate inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Tamoxifen inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Teniposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Thiotepa inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]
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CTD |
PMID:30863990 |
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NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279
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| G
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Abcb11
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ATP binding cassette subfamily B member 11
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decreases activity
|
ISO
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Clofazimine results in decreased activity of ABCB11 protein
|
CTD |
PMID:20829430 PMID:23956101 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
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| G
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Acaca
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acetyl-CoA carboxylase alpha
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increases expression
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EXP
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Clofazimine results in increased expression of ACACA mRNA
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CTD |
PMID:31393584 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
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| G
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Cebpa
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CCAAT/enhancer binding protein alpha
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increases expression
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EXP
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Clofazimine results in increased expression of CEBPA protein
|
CTD |
PMID:31393584 |
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NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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| G
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Dgat1
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diacylglycerol O-acyltransferase 1
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decreases expression
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EXP
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Clofazimine results in decreased expression of DGAT1 mRNA
|
CTD |
PMID:31393584 |
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NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
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| G
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Fas
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Fas cell surface death receptor
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increases expression
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EXP
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Clofazimine results in increased expression of FAS mRNA
|
CTD |
PMID:31393584 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
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| G
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Gstp1
|
glutathione S-transferase pi 1
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multiple interactions
|
ISO
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Clofazimine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
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CTD |
PMID:23769903 |
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NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
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| G
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Kcnh2
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potassium voltage-gated channel subfamily H member 2
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decreases activity
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ISO
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Clofazimine results in decreased activity of KCNH2 protein
|
CTD |
PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
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| G
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Pparg
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peroxisome proliferator-activated receptor gamma
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increases expression
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EXP
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Clofazimine results in increased expression of PPARG mRNA; Clofazimine results in increased expression of PPARG protein
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CTD |
PMID:31393584 |
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NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
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| G
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Srebf1
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sterol regulatory element binding transcription factor 1
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increases expression
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EXP
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Clofazimine results in increased expression of SREBF1 mRNA
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CTD |
PMID:31393584 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
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| G
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Zfp423
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zinc finger protein 423
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increases expression
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EXP
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Clofazimine results in increased expression of ZFP423 mRNA
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CTD |
PMID:31393584 |
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NCBI chr19:35,282,149...35,580,775
Ensembl chr19:35,282,110...35,580,773
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|
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| G
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Aak1
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AP2 associated kinase 1
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decreases phosphorylation
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ISO
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coumarin results in decreased phosphorylation of AAK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:120,845,012...121,009,170
Ensembl chr 4:120,858,557...121,004,236
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| G
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Aass
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aminoadipate-semialdehyde synthase
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decreases expression
|
EXP
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coumarin results in decreased expression of AASS mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600
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| G
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Aatf
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apoptosis antagonizing transcription factor
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increases phosphorylation
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ISO
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coumarin results in increased phosphorylation of AATF protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:69,796,502...69,889,671
Ensembl chr10:69,794,007...69,889,634
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| G
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Abcb11
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ATP binding cassette subfamily B member 11
|
affects expression
|
EXP
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coumarin affects the expression of ABCB11 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
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| G
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Abcc1
|
ATP binding cassette subfamily C member 1
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decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ABCC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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| G
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Abcc2
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ATP binding cassette subfamily C member 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ABCC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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| G
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Abcc3
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ATP binding cassette subfamily C member 3
|
increases expression
|
EXP
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coumarin results in increased expression of ABCC3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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| G
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Abcc4
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ATP binding cassette subfamily C member 4
|
increases phosphorylation
|
ISO
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coumarin results in increased phosphorylation of ABCC4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
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| G
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Abcc5
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ATP binding cassette subfamily C member 5
|
decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ABCC5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
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|
| G
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Abcf1
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ATP binding cassette subfamily F member 1
|
decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ABCF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:2,807,315...2,820,240
Ensembl chr20:2,807,106...2,820,240
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|
| G
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Abi1
|
abl-interactor 1
|
decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ABI1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:90,006,917...90,088,002
Ensembl chr17:90,006,925...90,087,827
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| G
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Abl1
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ABL proto-oncogene 1, non-receptor tyrosine kinase
|
decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ABL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
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|
| G
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Abl2
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ABL proto-oncogene 2, non-receptor tyrosine kinase
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affects phosphorylation
|
ISO
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coumarin affects the phosphorylation of ABL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:71,223,902...71,319,770
Ensembl chr13:71,224,019...71,389,775
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|
| G
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Ablim1
|
actin-binding LIM protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ABLIM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:266,088,868...266,377,169
Ensembl chr 1:266,088,870...266,377,098
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|
| G
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Acaa1a
|
acetyl-CoA acyltransferase 1A
|
increases expression
|
EXP
|
coumarin results in increased expression of ACAA1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241
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|
| G
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Acaa2
|
acetyl-CoA acyltransferase 2
|
affects expression
|
EXP
|
coumarin affects the expression of ACAA2 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420
|
|
| G
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Acap2
|
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ACAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:83,043,442...83,159,105
Ensembl chr11:83,043,511...83,159,107
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|
| G
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Acbd3
|
acyl-CoA binding domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ACBD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:94,987,643...95,016,356
Ensembl chr13:94,987,541...95,016,355
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|
| G
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Acd
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ACD, shelterin complex subunit and telomerase recruitment factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ACD protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326
|
|
| G
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Ache
|
acetylcholinesterase
|
multiple interactions
|
ISO
|
coumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [haloxon results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
|
CTD |
PMID:10421444 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
|
|
| G
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Acin1
|
apoptotic chromatin condensation inducer 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ACIN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:32,072,121...32,117,004
Ensembl chr15:32,072,123...32,117,166
|
|
| G
|
Acly
|
ATP citrate lyase
|
affects expression
|
EXP
|
coumarin affects the expression of ACLY mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
|
|
| G
|
Aco1
|
aconitase 1
|
affects expression
|
EXP
|
coumarin affects the expression of ACO1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
|
|
| G
|
Acot4
|
acyl-CoA thioesterase 4
|
increases expression
|
EXP
|
coumarin results in increased expression of ACOT4 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
|
|
| G
|
Acsm1
|
acyl-CoA synthetase medium-chain family member 1
|
increases expression
|
ISO
|
coumarin results in increased expression of ACSM1 mRNA
|
CTD |
PMID:17311802 |
|
NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:183,416,009...183,454,217
|
|
| G
|
Acss2
|
acyl-CoA synthetase short-chain family member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ACSS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830
|
|
| G
|
Actb
|
actin, beta
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ACTB protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242
|
|
| G
|
Adarb2
|
adenosine deaminase RNA specific B2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ADARB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:66,660,586...67,211,104
Ensembl chr17:66,665,506...67,210,749
|
|
| G
|
Adcy9
|
adenylate cyclase 9
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ADCY9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:11,645,373...11,768,462
Ensembl chr10:11,645,282...11,765,792
|
|
| G
|
Add1
|
adducin 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ADD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
|
|
| G
|
Add3
|
adducin 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ADD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504
|
|
| G
|
Adgrl3
|
adhesion G protein-coupled receptor L3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ADGRL3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418
|
|
| G
|
Adnp
|
activity-dependent neuroprotector homeobox
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ADNP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:177,310,258...177,340,379
Ensembl chr 3:177,310,258...177,336,188
|
|
| G
|
Adrm1
|
ADRM1 26S proteasome ubiquitin receptor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ADRM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483
|
|
| G
|
Aebp2
|
AE binding protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AEBP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422
|
|
| G
|
Afap1
|
actin filament associated protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AFAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:78,967,961...79,081,032
Ensembl chr14:78,967,961...79,080,939
|
|
| G
|
Aff1
|
ALF transcription elongation factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AFF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:6,165,864...6,328,848
Ensembl chr14:6,169,562...6,328,879
|
|
| G
|
Aff4
|
ALF transcription elongation factor 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AFF4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,999,579...38,080,580
|
|
| G
|
Aftph
|
aftiphilin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AFTPH protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:99,072,761...99,127,006
Ensembl chr14:99,072,761...99,126,727
|
|
| G
|
Ahctf1
|
AT hook containing transcription factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AHCTF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:94,013,894...94,068,348
Ensembl chr13:94,014,469...94,068,058
|
|
| G
|
Ahi1
|
Abelson helper integration site 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AHI1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:17,580,859...17,711,775
Ensembl chr 1:17,582,006...17,711,774
|
|
| G
|
Ahnak
|
AHNAK nucleoprotein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AHNAK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675
|
|
| G
|
Aif1l
|
allograft inflammatory factor 1-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AIF1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:35,627,239...35,651,793
Ensembl chr 3:35,627,239...35,651,793
|
|
| G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of AIFM1 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
|
|
| G
|
Ajuba
|
ajuba LIM protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AJUBA protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:31,989,796...32,000,042
Ensembl chr15:31,989,799...32,000,042
|
|
| G
|
Akap1
|
A-kinase anchoring protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AKAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:74,118,232...74,151,366
Ensembl chr10:74,119,124...74,138,190
|
|
| G
|
Akap11
|
A-kinase anchoring protein 11
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AKAP11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:60,320,839...60,365,480
Ensembl chr15:60,320,839...60,365,335
|
|
| G
|
Akap12
|
A-kinase anchoring protein 12
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AKAP12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557
|
|
| G
|
Akap13
|
A-kinase anchoring protein 13
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AKAP13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:138,724,150...139,029,401
|
|
| G
|
Akap8
|
A-kinase anchoring protein 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AKAP8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900
|
|
| G
|
Akr1b15
|
aldo-keto reductase family 1 member B15
|
increases expression
|
EXP
|
coumarin results in increased expression of AKR1B8 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of AKR1C6 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c3l1
|
aldo-keto reductase family 1 member C3-like 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of AKR1C3L1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr17:70,745,496...70,791,411
Ensembl chr17:70,745,496...70,791,322
|
|
| G
|
Akr1d1
|
aldo-keto reductase family 1, member D1
|
affects expression
|
EXP
|
coumarin affects the expression of AKR1D1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540
|
|
| G
|
Akr7a3
|
aldo-keto reductase family 7 member A3
|
increases expression
|
EXP
|
coumarin results in increased expression of AKR7A3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
ISO
|
coumarin analog results in decreased expression of and results in decreased phosphorylation of AKT1 protein
|
CTD |
PMID:32578917 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Akt1s1
|
AKT1 substrate 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AKT1S1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:104,469,803...104,476,167
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
increases expression
|
EXP
|
coumarin results in increased expression of ALDH1A1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Alkbh5
|
alkB homolog 5, RNA demethylase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ALKBH5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:45,844,411...45,865,853
Ensembl chr10:45,843,656...45,869,658
|
|
| G
|
Alox5
|
arachidonate 5-lipoxygenase
|
increases expression
|
EXP
|
coumarin results in increased expression of ALOX5 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
|
|
| G
|
Alpi
|
alkaline phosphatase, intestinal
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ALPI protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780
|
|
| G
|
Alpp
|
alkaline phosphatase, placental
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ALPP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451
|
|
| G
|
Alyref
|
Aly/REF export factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ALYREF protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:106,369,750...106,373,395
Ensembl chr10:106,369,750...106,373,395
|
|
| G
|
Amfr
|
autocrine motility factor receptor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AMFR protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:11,002,451...11,038,182
Ensembl chr19:11,002,101...11,038,364
|
|
| G
|
Amotl1
|
angiomotin-like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AMOTL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:19,634,510...19,748,869
|
|
| G
|
Amotl2
|
angiomotin like 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AMOTL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:112,182,060...112,198,032
Ensembl chr 8:112,181,863...112,198,030
|
|
| G
|
Ampd2
|
adenosine monophosphate deaminase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AMPD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:198,395,767...198,408,514
Ensembl chr 2:198,395,768...198,408,796
|
|
| G
|
Anapc1
|
anaphase promoting complex subunit 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ANAPC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:136,303,350...136,383,464
Ensembl chr 3:136,303,413...136,383,464
|
|
| G
|
Anapc2
|
anaphase promoting complex subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ANAPC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:28,484,590...28,496,338
Ensembl chr 3:28,484,614...28,496,337
|
|
| G
|
Ankib1
|
ankyrin repeat and IBR domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ANKIB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:31,288,393...31,412,500
Ensembl chr 4:31,288,142...31,412,504
|
|
| G
|
Ankrd11
|
ankyrin repeat domain containing 11
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ANKRD11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491
|
|
| G
|
Ankrd13d
|
ankyrin repeat domain 13D
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ANKRD13D protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:210,995,012...211,007,430
Ensembl chr 1:210,995,148...211,007,369
|
|
| G
|
Ankrd17
|
ankyrin repeat domain 17
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ANKRD17 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:18,007,342...18,145,980
Ensembl chr14:18,008,859...18,145,980
|
|
| G
|
Ankrd26
|
ankyrin repeat domain containing 26
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ANKRD26 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:153,342,901...153,412,321
Ensembl chr 4:153,343,578...153,412,256
|
|
| G
|
Anks1a
|
ankyrin repeat and sterile alpha motif domain containing 1A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ANKS1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:5,965,421...6,118,875
Ensembl chr20:5,965,028...6,118,875
|
|
| G
|
Anks3
|
ankyrin repeat and sterile alpha motif domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ANKS3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:11,121,504...11,142,261
Ensembl chr10:11,121,553...11,142,491
|
|
| G
|
Ankzf1
|
ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ANKZF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:84,136,862...84,143,830
Ensembl chr 9:84,136,862...84,145,091
|
|
| G
|
Anln
|
anillin, actin binding protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ANLN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
|
|
| G
|
Anxa2
|
annexin A2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ANXA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631
|
|
| G
|
Anxa7
|
annexin A7
|
increases expression
|
EXP
|
coumarin results in increased expression of ANXA7 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891
|
|
| G
|
Aoc3
|
amine oxidase, copper containing 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AOC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:86,773,018...86,780,961
|
|
| G
|
Ap2b1
|
adaptor related protein complex 2 subunit beta 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AP2B1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:68,596,925...68,702,547
Ensembl chr10:68,597,093...68,702,539
|
|
| G
|
Ap2m1
|
adaptor related protein complex 2 subunit mu 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AP2M1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
|
|
| G
|
Ap3d1
|
adaptor related protein complex 3 subunit delta 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of AP3D1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:9,620,968...9,656,342
|
|
| G
|
Ap4e1
|
adaptor related protein complex 4 subunit epsilon 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AP4E1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:134,726,338...134,792,820
Ensembl chr 3:134,726,287...134,792,818
|
|
| G
|
Apba3
|
amyloid beta precursor protein binding family A member 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of APBA3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,096,936...9,103,457
Ensembl chr 7:9,095,975...9,101,909
|
|
| G
|
Apbb3
|
amyloid beta precursor protein binding family B member 3
|
decreases expression
|
EXP
|
coumarin results in decreased expression of APBB3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr18:28,547,205...28,554,383
Ensembl chr18:28,547,205...28,554,383
|
|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of APC protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
| G
|
Apcs
|
amyloid P component, serum
|
decreases expression
|
EXP
|
coumarin results in decreased expression of APCS mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
|
|
| G
|
Api5
|
apoptosis inhibitor 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of API5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580
|
|
| G
|
Araf
|
A-Raf proto-oncogene, serine/threonine kinase
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARAF protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611
|
|
| G
|
Arfgap1
|
ARF GTPase activating protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARFGAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,462,125...188,477,515
Ensembl chr 3:188,465,648...188,511,078
|
|
| G
|
Arfgef2
|
ARF guanine nucleotide exchange factor 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARFGEF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:175,966,575...176,052,715
Ensembl chr 3:175,966,579...176,052,713
|
|
| G
|
Arg1
|
arginase 1
|
affects expression
|
EXP
|
coumarin affects the expression of ARG1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
|
|
| G
|
Arglu1
|
arginine and glutamate rich 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARGLU1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:87,455,097...87,479,148
Ensembl chr16:87,455,113...87,479,148
|
|
| G
|
Arhgap1
|
Rho GTPase activating protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ARHGAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154
|
|
| G
|
Arhgap18
|
Rho GTPase activating protein 18
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARHGAP18 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:20,222,948...20,456,827
Ensembl chr 1:20,222,954...20,456,670
|
|
| G
|
Arhgap21
|
Rho GTPase activating protein 21
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARHGAP21 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:88,256,961...88,380,478
Ensembl chr17:88,256,961...88,380,797
|
|
| G
|
Arhgap23
|
Rho GTPase activating protein 23
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ARHGAP23 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:82,891,021...82,993,230
Ensembl chr10:82,890,853...82,993,228
|
|
| G
|
Arhgap32
|
Rho GTPase activating protein 32
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARHGAP32 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:38,679,368...38,939,960
Ensembl chr 8:38,684,484...38,939,960
|
|
| G
|
Arhgap35
|
Rho GTPase activating protein 35
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ARHGAP35 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:86,330,566...86,447,414
Ensembl chr 1:86,330,566...86,447,414
|
|
| G
|
Arhgap45
|
Rho GTPase activating protein 45
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARHGAP45 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890
|
|
| G
|
Arhgap5
|
Rho GTPase activating protein 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARHGAP5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:75,711,199...75,774,636
Ensembl chr 6:75,711,515...75,774,636
|
|
| G
|
Arhgef11
|
Rho guanine nucleotide exchange factor 11
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ARHGEF11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:175,372,269...175,493,852
Ensembl chr 2:175,372,290...175,493,852
|
|
| G
|
Arhgef12
|
Rho guanine nucleotide exchange factor 12
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARHGEF12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:52,247,047...52,373,158
Ensembl chr 8:52,247,047...52,372,376
|
|
| G
|
Arhgef16
|
Rho guanine nucleotide exchange factor 16
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARHGEF16 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:170,126,573...170,148,624
Ensembl chr 5:170,126,575...170,148,624
|
|
| G
|
Arhgef18
|
Rho/Rac guanine nucleotide exchange factor 18
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ARHGEF18 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:6,192,958...6,300,997
Ensembl chr12:6,128,661...6,300,997
|
|
| G
|
Arhgef2
|
Rho/Rac guanine nucleotide exchange factor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARHGEF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
|
|
| G
|
Arid1a
|
AT-rich interaction domain 1A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ARID1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386
|
|
| G
|
Arid2
|
AT-rich interaction domain 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARID2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:129,326,371...129,443,813
Ensembl chr 7:129,324,137...129,443,187
|
|
| G
|
Arid4b
|
AT-rich interaction domain 4B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARID4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:55,833,908...55,958,382
Ensembl chr17:55,833,908...55,958,382
|
|
| G
|
Ark2n
|
arkadia (RNF111) N-terminal like PKA signaling regulator 2N
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARK2N protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:73,431,104...73,520,759
Ensembl chr18:73,431,104...73,518,144
|
|
| G
|
Arl6ip6
|
ARF like GTPase 6 interacting protein 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARL6IP6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:58,098,978...58,126,962
Ensembl chr 3:58,099,408...58,126,957
|
|
| G
|
Armc1
|
armadillo repeat containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ARMC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:103,524,333...103,568,355
Ensembl chr 2:103,524,333...103,568,355
|
|
| G
|
Ash1l
|
ASH1 like histone lysine methyltransferase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ASH1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847
|
|
| G
|
Asmtl
|
acetylserotonin O-methyltransferase-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ASMTL protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:21,429,119...21,431,847
Ensembl chr12:21,429,171...21,431,847
|
|
| G
|
Asns
|
asparagine synthetase (glutamine-hydrolyzing)
|
increases expression
|
EXP
|
coumarin results in increased expression of ASNS mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
|
Aspscr1
|
ASPSCR1 tether for SLC2A4, UBX domain containing
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ASPSCR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:106,450,600...106,488,231
Ensembl chr10:106,450,567...106,488,579
|
|
| G
|
Asxl1
|
ASXL transcriptional regulator 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ASXL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:162,273,828...162,341,742
Ensembl chr 3:162,273,828...162,341,742
|
|
| G
|
Atad1
|
ATPase family, AAA domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATAD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:239,957,329...240,023,792
Ensembl chr 1:239,957,882...240,009,822
|
|
| G
|
Atad2
|
ATPase family, AAA domain containing 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATAD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
|
|
| G
|
Atad2b
|
ATPase family, AAA domain containing 2B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATAD2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:33,646,075...33,789,532
Ensembl chr 6:33,646,075...33,789,532
|
|
| G
|
Atf7
|
activating transcription factor 7
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATF7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,537,351...135,649,188
Ensembl chr 7:135,542,111...135,599,899
|
|
| G
|
Atf7ip
|
activating transcription factor 7 interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATF7IP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:171,117,122...171,202,871
Ensembl chr 4:171,117,122...171,202,867
|
|
| G
|
Atg13
|
autophagy related 13
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ATG13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:98,102,831...98,136,741
Ensembl chr 3:98,101,552...98,136,743
|
|
| G
|
Atg16l1
|
autophagy related 16-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATG16L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:95,869,839...95,905,354
Ensembl chr 9:95,869,865...95,905,357
|
|
| G
|
Atg2b
|
autophagy related 2B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ATG2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:130,286,979...130,357,109
Ensembl chr 6:130,286,986...130,357,109
|
|
| G
|
Atg9a
|
autophagy related 9A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATG9A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:84,126,071...84,136,666
|
|
| G
|
Atn1
|
atrophin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,240,573...159,254,378
Ensembl chr 4:159,237,562...159,254,418
|
|
| G
|
Atp11c
|
ATPase phospholipid transporting 11C
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATP11C protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:143,600,763...143,788,407
Ensembl chr X:143,600,767...143,788,432
|
|
| G
|
Atp1a1
|
ATPase Na+/K+ transporting subunit alpha 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ATP1A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
|
|
| G
|
Atp2b1
|
ATPase plasma membrane Ca2+ transporting 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ATP2B1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904
|
|
| G
|
Atp5if1
|
ATP synthase inhibitory factor subunit 1
|
increases expression
|
EXP
|
coumarin results in increased expression of ATP5IF1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677
|
|
| G
|
Atp6v0a2
|
ATPase H+ transporting V0 subunit a2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATP6V0A2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860
|
|
| G
|
Atrn
|
attractin
|
decreases expression increases phosphorylation
|
EXP ISO
|
coumarin results in decreased expression of ATRN mRNA coumarin results in increased phosphorylation of ATRN protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360
|
|
| G
|
Atrx
|
ATRX, chromatin remodeler
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATRX protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:74,916,548...75,062,880
Ensembl chr X:74,916,548...75,062,880
|
|
| G
|
Atxn1l
|
ataxin 1 like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ATXN1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:54,609,852...54,621,024
Ensembl chr19:54,609,132...54,680,582
|
|
| G
|
Atxn2
|
ataxin 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATXN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:40,413,657...40,509,895
Ensembl chr12:40,414,904...40,510,473
|
|
| G
|
Atxn2l
|
ataxin 2-like
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ATXN2L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:190,508,878...190,526,263
Ensembl chr 1:190,508,878...190,520,579
|
|
| G
|
Atxn7l3
|
ataxin 7-like 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ATXN7L3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:87,742,993...87,750,247
Ensembl chr10:87,744,369...87,750,245
|
|
| G
|
Avl9
|
AVL9 cell migration associated
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of AVL9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:87,291,062...87,338,537
Ensembl chr 4:87,291,798...87,331,916
|
|
| G
|
Avpr1a
|
arginine vasopressin receptor 1A
|
decreases expression
|
EXP
|
coumarin results in decreased expression of AVPR1A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837
|
|
| G
|
Azgp1
|
alpha-2-glycoprotein 1, zinc-binding
|
affects expression
|
EXP
|
coumarin affects the expression of AZGP1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020
|
|
| G
|
Azin1
|
antizyme inhibitor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of AZIN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:71,539,711...71,566,515
Ensembl chr 7:71,539,711...71,566,515
|
|
| G
|
B4galt1
|
beta-1,4-galactosyltransferase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of B4GALT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445
|
|
| G
|
Babam1
|
BRISC and BRCA1 A complex member 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BABAM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:18,102,885...18,108,916
Ensembl chr16:18,102,815...18,108,932
|
|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
increases expression
|
ISO
|
coumarin analog results in increased expression of BAD mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
| G
|
Bag3
|
BAG cochaperone 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BAG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
|
|
| G
|
Bag6
|
BAG cochaperone 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BAG6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,680,607...3,693,329
|
|
| G
|
Baiap2
|
BAR/IMD domain containing adaptor protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BAIAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:105,721,371...105,788,549
Ensembl chr10:105,721,417...105,788,549
|
|
| G
|
Baiap2l1
|
BAR/IMD domain containing adaptor protein 2 like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BAIAP2L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:15,364,090...15,453,602
Ensembl chr12:15,364,109...15,453,605
|
|
| G
|
Bak1
|
BCL2-antagonist/killer 1
|
increases expression
|
ISO
|
coumarin analog results in increased expression of BAK1 protein
|
CTD |
PMID:31199928 |
|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
|
|
| G
|
Banf1
|
barrier to autointegration nuclear assembly factor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BANF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552
|
|
| G
|
Bap1
|
BRCA1 associated deubiquitinase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,452,974...6,461,952
|
|
| G
|
Basp1
|
brain abundant, membrane attached signal protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BASP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:77,546,092...77,597,178
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression
|
ISO
|
coumarin analog results in increased expression of BAX mRNA; coumarin results in increased expression of BAX protein
|
CTD |
PMID:15964220 PMID:32578917 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Baz1b
|
bromodomain adjacent to zinc finger domain, 1B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BAZ1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:27,068,541...27,126,511
Ensembl chr12:27,068,541...27,126,511
|
|
| G
|
Baz2a
|
bromodomain adjacent to zinc finger domain, 2A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BAZ2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:1,107,377...1,145,507
Ensembl chr 7:1,107,796...1,145,507
|
|
| G
|
Bbc3
|
Bcl-2 binding component 3
|
increases expression
|
ISO
|
coumarin analog results in increased expression of BBC3 protein
|
CTD |
PMID:31199928 |
|
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
|
|
| G
|
Bbln
|
bublin coiled coil protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BBLN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:36,072,325...36,075,070
Ensembl chr 3:36,072,328...36,075,093
|
|
| G
|
Bbox1
|
gamma-butyrobetaine hydroxylase 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of BBOX1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064
|
|
| G
|
Bbx
|
BBX high mobility group box domain containing
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BBX protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:63,850,034...64,097,700
Ensembl chr11:63,850,018...64,093,265
|
|
| G
|
Bcas3
|
BCAS3, microtubule associated cell migration factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BCAS3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:70,711,084...71,170,492
Ensembl chr10:70,711,525...71,170,803
|
|
| G
|
Bckdha
|
branched chain keto acid dehydrogenase E1 subunit alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BCKDHA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:90,266,731...90,295,521
Ensembl chr 1:90,261,629...90,295,749
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of BCL2 mRNA; coumarin results in decreased expression of BCL2 protein
|
CTD |
PMID:15964220 PMID:32578917 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2l13
|
Bcl2-like 13
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BCL2L13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:155,728,284...155,785,058
Ensembl chr 4:155,728,284...155,781,158
|
|
| G
|
Bcl7b
|
BAF chromatin remodeling complex subunit BCL7B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BCL7B protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:27,133,412...27,146,631
Ensembl chr12:27,133,412...27,146,636
|
|
| G
|
Bcl7c
|
BAF chromatin remodeling complex subunit BCL7C
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BCL7C protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,703,432...191,754,751
Ensembl chr 1:191,691,089...191,754,641
|
|
| G
|
Bcl9l
|
BCL9 like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BCL9L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:53,708,770...53,738,880
Ensembl chr 8:53,708,770...53,737,395
|
|
| G
|
Bclaf1
|
BCL2-associated transcription factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BCLAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:16,914,118...16,936,801
|
|
| G
|
Bclaf3
|
BCLAF1 and THRAP3 family member 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BCLAF3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:39,065,842...39,137,521
Ensembl chr X:39,072,840...39,137,448
|
|
| G
|
Bcor
|
BCL6 co-repressor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BCOR protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:13,282,431...13,402,254
Ensembl chr X:13,360,376...13,402,254
|
|
| G
|
Bcorl1
|
BCL6 co-repressor-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BCORL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:132,394,703...132,462,414
Ensembl chr X:132,397,069...132,461,976
|
|
| G
|
Bcr
|
BCR activator of RhoGEF and GTPase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BCR protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333
|
|
| G
|
Bdp1
|
BDP1 general transcription factor IIIB subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BDP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:33,112,518...33,204,270
Ensembl chr 2:33,112,518...33,204,241
|
|
| G
|
Begain
|
brain-enriched guanylate kinase-associated
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BEGAIN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:133,708,010...133,744,264
Ensembl chr 6:133,708,007...133,744,526
|
|
| G
|
Best1
|
bestrophin 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BEST1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:216,054,395...216,071,012
Ensembl chr 1:216,054,395...216,070,974
|
|
| G
|
Bet1l
|
Bet1 golgi vesicular membrane trafficking protein-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BET1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:205,361,041...205,365,036
Ensembl chr 1:205,361,041...205,364,706
|
|
| G
|
Bhlha15
|
basic helix-loop-helix family, member a15
|
increases expression
|
EXP
|
coumarin results in increased expression of BHLHA15 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515
|
|
| G
|
Bhmt
|
betaine-homocysteine S-methyltransferase
|
decreases expression affects expression
|
EXP
|
coumarin results in decreased expression of BHMT mRNA coumarin affects the expression of BHMT mRNA
|
CTD |
PMID:16963487 PMID:18480146 |
|
NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715
|
|
| G
|
Bid
|
BH3 interacting domain death agonist
|
increases expression
|
ISO
|
coumarin analog results in increased expression of BID mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
|
|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of BIRC5 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
|
Bmp2k
|
BMP-2 inducible kinase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BMP2K protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:12,785,169...12,882,676
Ensembl chr14:12,785,169...12,882,657
|
|
| G
|
Bms1
|
BMS1 ribosome biogenesis factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BMS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:153,230,471...153,267,437
Ensembl chr 4:153,230,471...153,267,429
|
|
| G
|
Bnip3
|
BCL2 interacting protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BNIP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
|
|
| G
|
Bod1l1
|
biorientation of chromosomes in cell division 1-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BOD1L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:73,320,880...73,375,662
Ensembl chr14:73,320,832...73,375,658
|
|
| G
|
Bop1
|
BOP1 ribosomal biogenesis factor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BOP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529
|
|
| G
|
Bptf
|
bromodomain PHD finger transcription factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BPTF protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:92,480,007...92,582,485
Ensembl chr10:92,480,007...92,582,413
|
|
| G
|
Braf
|
B-Raf proto-oncogene, serine/threonine kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BRAF protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931
|
|
| G
|
Brap
|
BRCA1 associated protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BRAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:40,535,232...40,561,726
Ensembl chr12:40,535,232...40,561,726
|
|
| G
|
Brat1
|
BRCA1-associated ATM activator 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BRAT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:19,043,004...19,065,686
Ensembl chr12:19,042,591...19,055,369
|
|
| G
|
Brca1
|
BRCA1, DNA repair associated
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BRCA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
|
|
| G
|
Brd1
|
bromodomain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BRD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:121,653,859...121,701,700
Ensembl chr 7:121,653,859...121,701,700
|
|
| G
|
Brd2
|
bromodomain containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BRD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290
|
|
| G
|
Brd3
|
bromodomain containing 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BRD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:31,173,332...31,227,749
Ensembl chr 3:31,173,332...31,227,629
|
|
| G
|
Brd4
|
bromodomain containing 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BRD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923
|
|
| G
|
Brd9
|
bromodomain containing 9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BRD9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:31,158,546...31,185,812
Ensembl chr 1:31,158,546...31,186,125
|
|
| G
|
Brf1
|
BRF1 general transcription factor IIIB subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BRF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386
|
|
| G
|
Brip1
|
BRCA1 interacting DNA helicase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BRIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:71,402,035...71,528,083
Ensembl chr10:71,401,151...71,575,206
|
|
| G
|
Brix1
|
biogenesis of ribosomes BRX1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BRIX1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:61,177,769...61,188,647
Ensembl chr 2:61,177,771...61,188,647
|
|
| G
|
Brpf1
|
bromodomain and PHD finger containing, 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BRPF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:148,011,977...148,028,431
Ensembl chr 4:148,011,931...148,028,424
|
|
| G
|
Brsk2
|
BR serine/threonine kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BRSK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:206,465,040...206,518,156
Ensembl chr 1:206,465,040...206,518,156
|
|
| G
|
Brwd1
|
bromodomain and WD repeat domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of BRWD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:48,756,174...48,853,692
Ensembl chr11:48,756,811...48,848,256
|
|
| G
|
Bsdc1
|
BSD domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BSDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:147,083,044...147,113,997
Ensembl chr 5:147,079,838...147,114,241
|
|
| G
|
Bsg
|
basigin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BSG protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
|
|
| G
|
Bud13
|
BUD13 homolog
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of BUD13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:55,471,818...55,487,652
Ensembl chr 8:55,471,810...55,487,649
|
|
| G
|
Bysl
|
bystin-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of BYSL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:20,880,026...20,890,900
|
|
| G
|
C13h1orf226
|
similar to human chromosome 1 open reading frame 226
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of C1ORF226 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:85,063,350...85,071,435
Ensembl chr13:85,063,350...85,353,741
|
|
| G
|
C14h22orf31
|
similar to human chromosome 22 open reading frame 31
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of C22ORF31 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:84,373,414...84,374,948
|
|
| G
|
C18h18orf21
|
similar to human chromosome 18 open reading frame 21
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RMP24 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:16,054,038...16,062,645
Ensembl chr18:16,053,880...16,064,239
|
|
| G
|
C19h16orf87
|
similar to human chromosome 16 open reading frame 87
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of C16ORF87 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:37,800,187...37,827,091
Ensembl chr19:37,799,799...37,827,452
|
|
| G
|
C1h19orf47
|
similar to human chromosome 19 open reading frame 47
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of C19ORF47 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:91,971,879...92,010,938
Ensembl chr 1:91,971,931...91,999,771
|
|
| G
|
C1h9orf40
|
similar to human chromosome 9 open reading frame 40
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of C9ORF40 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:225,555,300...225,559,509
Ensembl chr 1:225,555,280...225,559,693
|
|
| G
|
C2cd2
|
C2 calcium-dependent domain containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of C2CD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:50,694,680...50,759,096
Ensembl chr11:50,694,563...50,759,016
|
|
| G
|
C2cd2l
|
C2CD2-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of C2CD2L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:53,544,887...53,557,127
Ensembl chr 8:53,544,892...53,555,153
|
|
| G
|
C2cd5
|
C2 calcium-dependent domain containing 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of C2CD5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:177,700,515...177,790,576
Ensembl chr 4:177,700,516...177,786,717
|
|
| G
|
C2h1orf52
|
similar to human chromosome 1 open reading frame 52
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of C1ORF52 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:237,510,974...237,520,346
Ensembl chr 2:237,513,711...237,520,346
|
|
| G
|
C5
|
complement C5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of C5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468
|
|
| G
|
C5h1orf174
|
similar to human chromosome 1 open reading frame 174
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of C1ORF174 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:169,798,004...169,802,449
Ensembl chr 5:169,797,951...169,802,448
|
|
| G
|
C9h2orf49
|
similar to human chromosome 2 open reading frame 49
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of C2ORF49 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:52,863,565...52,874,234
Ensembl chr 9:52,863,542...52,874,234
|
|
| G
|
Ca1
|
carbonic anhydrase 1
|
decreases activity
|
ISO
|
coumarin results in decreased activity of CA1 protein
|
CTD |
PMID:22077347 |
|
NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454
|
|
| G
|
Ca3
|
carbonic anhydrase 3
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CA3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
|
|
| G
|
Caap1
|
caspase activity and apoptosis inhibitor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CAAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:114,428,991...114,530,047
Ensembl chr 5:114,432,379...114,530,047
|
|
| G
|
Cables1
|
Cdk5 and Abl enzyme substrate 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CABLES1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956
|
|
| G
|
Cacna1a
|
calcium voltage-gated channel subunit alpha1 A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CACNA1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599
|
|
| G
|
Cald1
|
caldesmon 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CALD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085
|
|
| G
|
Camkk2
|
calcium/calmodulin-dependent protein kinase kinase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CAMKK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:39,451,828...39,505,719
Ensembl chr12:39,451,834...39,514,964
|
|
| G
|
Camsap1
|
calmodulin regulated spectrin-associated protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CAMSAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:29,144,318...29,206,382
Ensembl chr 3:29,144,318...29,204,184
|
|
| G
|
Cap2
|
cyclase associated actin cytoskeleton regulatory protein 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:18,260,462...18,409,681
Ensembl chr17:18,261,646...18,409,563
|
|
| G
|
Capn1
|
calpain 1
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CAPN1 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445
|
|
| G
|
Capza2
|
capping actin protein of muscle Z-line subunit alpha 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CAPZA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938
|
|
| G
|
Car2
|
carbonic anhydrase 2
|
increases expression decreases activity
|
EXP ISO
|
coumarin results in increased expression of CA2 mRNA coumarin results in decreased activity of CA2 protein
|
CTD |
PMID:18480146 PMID:22077347 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
| G
|
Carhsp1
|
calcium regulated heat stable protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CARHSP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770
|
|
| G
|
Carmil1
|
capping protein regulator and myosin 1 linker 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CARMIL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:41,235,819...41,516,204
Ensembl chr17:41,236,229...41,516,221
|
|
| G
|
Casc3
|
CASC3 exon junction complex subunit
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CASC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:84,264,157...84,286,639
Ensembl chr10:84,265,033...84,286,637
|
|
| G
|
Caskin2
|
cask-interacting protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CASKIN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,526,131...101,540,362
Ensembl chr10:101,526,195...101,540,349
|
|
| G
|
Casp2
|
caspase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CASP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022
|
|
| G
|
Casp3
|
caspase 3
|
increases cleavage increases expression
|
ISO
|
coumarin analog results in increased cleavage of CASP3 protein coumarin analog results in increased expression of CASP3 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Casp7
|
caspase 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CASP7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
|
|
| G
|
Casp8
|
caspase 8
|
increases expression
|
ISO
|
coumarin analog results in increased expression of CASP8 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
| G
|
Casp8ap2
|
caspase 8 associated protein 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CASP8AP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
|
|
| G
|
Casp9
|
caspase 9
|
increases expression
|
ISO
|
coumarin analog results in increased expression of CASP9 mRNA
|
CTD |
PMID:32578917 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Cat
|
catalase
|
multiple interactions decreases activity
|
EXP ISO
|
coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein] coumarin analog results in decreased activity of CAT protein
|
CTD |
PMID:21630391 PMID:32578917 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Cavin1
|
caveolae associated protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CAVIN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:86,384,401...86,398,240
Ensembl chr10:86,384,401...86,396,383
|
|
| G
|
Cbarp
|
CACN subunit beta associated regulatory protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CBARP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:10,217,314...10,225,855
Ensembl chr 7:10,217,328...10,225,854
|
|
| G
|
Cbll1
|
Cbl proto-oncogene like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CBLL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:53,798,712...53,812,890
Ensembl chr 6:53,798,712...53,813,880
|
|
| G
|
Cbr1
|
carbonyl reductase 1
|
increases expression
|
EXP
|
coumarin results in increased expression of CBR1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
|
|
| G
|
Cc2d1a
|
coiled-coil and C2 domain containing 1A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CC2D1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:40,916,587...40,931,702
Ensembl chr19:40,916,532...40,931,701
|
|
| G
|
Ccdc102a
|
coiled-coil domain containing 102A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCDC102A protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:10,108,553...10,124,652
Ensembl chr19:10,109,364...10,124,652
|
|
| G
|
Ccdc120
|
coiled-coil domain containing 120
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCDC120 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:17,437,219...17,443,716
Ensembl chr X:17,425,624...17,444,717
|
|
| G
|
Ccdc168
|
coiled-coil domain containing 168
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LRTM3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:53,690,704...53,728,801
Ensembl chr 9:53,690,786...53,727,639
|
|
| G
|
Ccdc6
|
coiled-coil domain containing 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CCDC6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227
|
|
| G
|
Ccdc71
|
coiled-coil domain containing 71
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCDC71 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:118,025,192...118,040,143
Ensembl chr 8:118,003,244...118,046,209
|
|
| G
|
Ccdc86
|
coiled-coil domain containing 86
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCDC86 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:217,015,059...217,021,439
Ensembl chr 1:217,014,848...217,021,468
|
|
| G
|
Ccdc9
|
coiled-coil domain containing 9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCDC9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:86,105,717...86,119,811
Ensembl chr 1:86,105,800...86,119,884
|
|
| G
|
Ccna2
|
cyclin A2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CCNA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
|
|
| G
|
Ccnb2
|
cyclin B2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CCNB2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
|
|
| G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CCND1 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccne1
|
cyclin E1
|
decreases expression increases expression
|
ISO EXP
|
coumarin analog results in decreased expression of CCNE1 mRNA coumarin results in increased expression of CCNE1 mRNA
|
CTD |
PMID:18480146 PMID:32578917 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
|
|
| G
|
Ccne2
|
cyclin E2
|
increases expression
|
EXP
|
coumarin results in increased expression of CCNE2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
|
|
| G
|
Ccnk
|
cyclin K
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCNK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:132,854,700...132,877,602
|
|
| G
|
Ccnl1
|
cyclin L1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCNL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468
|
|
| G
|
Ccnt1
|
cyclin T1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCNT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938
|
|
| G
|
Cct3
|
chaperonin containing TCP1 subunit 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCT3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925
|
|
| G
|
Cct7
|
chaperonin containing TCP1 subunit 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CCT7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973
|
|
| G
|
Cd109
|
CD109 molecule
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CD109 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:88,334,736...88,449,463
Ensembl chr 8:88,334,736...88,449,462
|
|
| G
|
Cd44
|
CD44 molecule
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CD44 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Cdc25b
|
cell division cycle 25B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDC25B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492
|
|
| G
|
Cdc27
|
cell division cycle 27
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CDC27 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:89,900,676...89,949,770
Ensembl chr10:89,900,684...89,949,770
|
|
| G
|
Cdc37
|
cell division cycle 37, HSP90 cochaperone
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDC37 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:27,948,016...27,983,931
|
|
| G
|
Cdc37l1
|
cell division cycle 37-like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDC37L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:236,118,630...236,147,527
Ensembl chr 1:236,118,555...236,207,079
|
|
| G
|
Cdc42bpb
|
CDC42 binding protein kinase beta
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CDC42BPB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:136,154,905...136,241,259
Ensembl chr 6:136,154,905...136,237,570
|
|
| G
|
Cdc42ep1
|
CDC42 effector protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDC42EP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:112,275,759...112,283,665
Ensembl chr 7:112,275,792...112,283,664
|
|
| G
|
Cdc42ep3
|
CDC42 effector protein 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDC42EP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:21,463,081...21,483,553
Ensembl chr 6:21,461,762...21,508,540
|
|
| G
|
Cdc42ep4
|
CDC42 effector protein 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CDC42EP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:99,271,750...99,298,551
Ensembl chr10:99,267,540...99,300,168
|
|
| G
|
Cdc5l
|
cell division cycle 5-like
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CDC5L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:23,062,205...23,100,899
|
|
| G
|
Cdca3
|
cell division cycle associated 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CDCA3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:159,321,014...159,325,068
|
|
| G
|
Cdca5
|
cell division cycle associated 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CDCA5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,807,863...212,821,313
Ensembl chr 1:212,804,014...212,821,309
|
|
| G
|
Cdca7l
|
cell division cycle associated 7 like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDCA7L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:144,936,885...144,982,844
Ensembl chr 6:144,908,171...144,982,843
|
|
| G
|
Cdh1
|
cadherin 1
|
increases expression
|
ISO
|
coumarin analog results in increased expression of CDH1 mRNA; coumarin analog results in increased expression of CDH1 protein
|
CTD |
PMID:32578917 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
|
|
| G
|
Cdh2
|
cadherin 2
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CDH2 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CDK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
|
|
| G
|
Cdk11b
|
cyclin-dependent kinase 11B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CDK11B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:171,495,042...171,521,143
Ensembl chr 5:171,495,776...171,521,145
|
|
| G
|
Cdk12
|
cyclin-dependent kinase 12
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CDK12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183 Ensembl chr10:83,767,206...83,777,183
|
|
| G
|
Cdk13
|
cyclin-dependent kinase 13
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CDK13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257
|
|
| G
|
Cdk14
|
cyclin-dependent kinase 14
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDK14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651
|
|
| G
|
Cdk16
|
cyclin-dependent kinase 16
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDK16 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:4,046,330...4,057,825
Ensembl chr X:4,026,866...4,057,380
|
|
| G
|
Cdk2
|
cyclin dependent kinase 2
|
decreases expression increases phosphorylation
|
ISO
|
coumarin analog results in decreased expression of CDK2 mRNA coumarin results in increased phosphorylation of CDK2 protein
|
CTD |
PMID:32578917 PMID:35688186 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
|
|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CDK4 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
| G
|
Cdk5rap3
|
CDK5 regulatory subunit associated protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CDK5RAP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:82,390,845...82,402,814
Ensembl chr10:82,390,845...82,400,001
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression
|
ISO
|
coumarin analog results in increased expression of CDKN1A mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn3
|
cyclin-dependent kinase inhibitor 3
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CDKN3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
|
|
| G
|
Cdo1
|
cysteine dioxygenase type 1
|
affects expression
|
EXP
|
coumarin affects the expression of CDO1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
|
|
| G
|
Cdr2l
|
cerebellar degeneration-related protein 2-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDR2L protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,123,777...101,137,634
Ensembl chr10:101,123,777...101,137,634
|
|
| G
|
Cdyl
|
chromodomain Y-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CDYL protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:29,188,697...29,409,805
Ensembl chr17:29,188,698...29,409,757
|
|
| G
|
Cenpc
|
centromere protein C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CENPC protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:22,342,910...22,401,522
Ensembl chr14:22,342,927...22,438,590
|
|
| G
|
Cenpt
|
centromere protein T
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CENPT protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:50,644,548...50,651,048
Ensembl chr19:50,634,368...50,651,037
|
|
| G
|
Cenpv
|
centromere protein V
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CENPV protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:47,713,778...47,746,800
Ensembl chr10:47,713,778...47,727,679
|
|
| G
|
Cep131
|
centrosomal protein 131
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CEP131 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:105,844,433...105,868,811
Ensembl chr10:105,844,433...105,868,797
|
|
| G
|
Cep152
|
centrosomal protein 152
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CEP152 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:133,243,979...133,332,271
Ensembl chr 3:133,263,174...133,331,655 Ensembl chr 3:133,263,174...133,331,655
|
|
| G
|
Cep162
|
centrosomal protein 162
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CEP162 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:97,029,677...97,088,243
Ensembl chr 8:97,029,677...97,088,207
|
|
| G
|
Cep170
|
centrosomal protein 170
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CEP170 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:91,201,808...91,285,990
Ensembl chr13:91,201,808...91,285,990
|
|
| G
|
Cep170b
|
centrosomal protein 170B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CEP170B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:137,602,707...137,627,750
Ensembl chr 6:137,602,707...137,627,750
|
|
| G
|
Cep72
|
centrosomal protein 72
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CEP72 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:31,053,884...31,083,863
Ensembl chr 1:31,053,914...31,083,863
|
|
| G
|
Cep76
|
centrosomal protein 76
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CEP76 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:63,444,389...63,478,358
Ensembl chr18:63,443,746...63,478,358
|
|
| G
|
Cep95
|
centrosomal protein 95
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CEP95 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:92,231,829...92,259,813
Ensembl chr10:92,231,512...92,259,810
|
|
| G
|
Ces1d
|
carboxylesterase 1D
|
increases expression
|
ISO
|
coumarin results in increased expression of CES1 mRNA
|
CTD |
PMID:17311802 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
|
|
| G
|
Cfap74
|
cilia and flagella associated protein 74
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CFAP74 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:171,252,907...171,328,351
Ensembl chr 5:171,262,113...171,328,349
|
|
| G
|
Cfl2
|
cofilin 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CFL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:78,090,843...78,094,888
|
|
| G
|
Chaf1a
|
chromatin assembly factor 1 subunit A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CHAF1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:961,225...987,825
Ensembl chr 9:961,084...987,868
|
|
| G
|
Chaf1b
|
chromatin assembly factor 1 subunit B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CHAF1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733
|
|
| G
|
Champ1
|
chromosome alignment maintaining phosphoprotein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CHAMP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:82,436,172...82,447,144
Ensembl chr16:82,434,823...82,458,984
|
|
| G
|
Chchd3
|
coiled-coil-helix-coiled-coil-helix domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CHCHD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:62,327,574...62,584,085
Ensembl chr 4:62,327,576...62,584,035
|
|
| G
|
Chd1
|
chromodomain helicase DNA binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CHD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:65,334,905...65,402,270
Ensembl chr 1:65,335,218...65,401,280
|
|
| G
|
Chd3
|
chromodomain helicase DNA binding protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CHD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:54,562,437...54,588,842
Ensembl chr10:54,562,437...54,588,810
|
|
| G
|
Chd4
|
chromodomain helicase DNA binding protein 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CHD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:159,584,654...159,617,866
|
|
| G
|
Chd7
|
chromodomain helicase DNA binding protein 7
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CHD7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:26,609,245...26,792,736
Ensembl chr 5:26,609,407...26,792,734
|
|
| G
|
Chd8
|
chromodomain helicase DNA binding protein 8
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CHD8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:27,379,285...27,438,959
Ensembl chr15:27,379,285...27,417,851
|
|
| G
|
Chd9
|
chromodomain helicase DNA binding protein 9
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CHD9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:32,114,379...32,337,488
Ensembl chr19:32,115,920...32,319,042
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CHEK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chrnb4
|
cholinergic receptor nicotinic beta 4 subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CHRNB4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:64,313,669...64,333,248
|
|
| G
|
Cir1
|
corepressor interacting with RBPJ, CIR1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CIRSR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:78,566,438...78,596,309
Ensembl chr 3:78,566,438...78,596,309
|
|
| G
|
Cisd3
|
CDGSH iron sulfur domain 3
|
increases expression
|
EXP
|
coumarin results in increased expression of CISD3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:83,175,708...83,178,739
Ensembl chr10:83,175,568...83,178,751
|
|
| G
|
Cit
|
citron rho-interacting serine/threonine kinase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CIT protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656
|
|
| G
|
Ciz1
|
CDKN1A interacting zinc finger protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CIZ1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:36,055,753...36,071,510
Ensembl chr 3:36,056,370...36,075,192
|
|
| G
|
Ckap4
|
cytoskeleton-associated protein 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CKAP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:21,118,527...21,126,624
Ensembl chr 7:21,118,085...21,126,624
|
|
| G
|
Ckap5
|
cytoskeleton associated protein 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CKAP5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049
|
|
| G
|
Clasp1
|
cytoplasmic linker associated protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CLASP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:32,046,362...32,267,954
Ensembl chr13:32,046,444...32,267,924
|
|
| G
|
Clasp2
|
cytoplasmic linker associated protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CLASP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:122,555,524...122,737,587
|
|
| G
|
Clasrp
|
CLK4-associating serine/arginine rich protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CLASRP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:88,360,235...88,384,343
Ensembl chr 1:88,360,235...88,384,343
|
|
| G
|
Clcc1
|
chloride channel CLIC-like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CLCC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:198,984,455...199,015,015
Ensembl chr 2:198,984,495...199,015,014
|
|
| G
|
Clcn7
|
chloride voltage-gated channel 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CLCN7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:14,656,261...14,681,632
Ensembl chr10:14,656,245...14,681,631
|
|
| G
|
Cldn3
|
claudin 3
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CLDN3 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841
|
|
| G
|
Cldn4
|
claudin 4
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CLDN4 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958
|
|
| G
|
Clic1
|
chloride intracellular channel 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CLIC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367
|
|
| G
|
Clip1
|
CAP-GLY domain containing linker protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CLIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779
|
|
| G
|
Clk1
|
CDC-like kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CLK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:67,441,962...67,453,180
Ensembl chr 9:67,441,952...67,451,187
|
|
| G
|
Clk3
|
CDC-like kinase 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CLK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:67,048,121...67,063,192
Ensembl chr 8:67,048,123...67,062,881
|
|
| G
|
Cln6
|
CLN6, transmembrane ER protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CLN6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:72,198,773...72,213,777
Ensembl chr 8:72,198,712...72,213,776
|
|
| G
|
Clspn
|
claspin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CLSPN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:144,134,619...144,169,531
Ensembl chr 5:144,134,632...144,169,530
|
|
| G
|
Cmip
|
c-Maf-inducing protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CMIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:62,213,402...62,419,443
Ensembl chr19:62,213,365...62,417,500
|
|
| G
|
Cmklr1
|
chemerin chemokine-like receptor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CMKLR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:48,634,929...48,687,833
Ensembl chr12:48,634,003...48,691,458
|
|
| G
|
Cmtr1
|
cap methyltransferase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CMTR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:7,724,286...7,784,787
Ensembl chr20:7,683,946...7,784,263
|
|
| G
|
Cnnm2
|
cyclin and CBS domain divalent metal cation transport mediator 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CNNM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:255,585,063...255,709,455
Ensembl chr 1:255,585,095...255,704,849
|
|
| G
|
Cnnm3
|
cyclin and CBS domain divalent metal cation transport mediator 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CNNM3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:46,251,252...46,266,613
Ensembl chr 9:46,251,265...46,266,613
|
|
| G
|
Cobl
|
cordon-bleu WH2 repeat protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of COBL protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:91,041,721...91,274,272
Ensembl chr14:91,041,721...91,274,257
|
|
| G
|
Cobll1
|
cordon-bleu WH2 repeat protein-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of COBLL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:70,161,369...70,324,844
Ensembl chr 3:70,161,372...70,323,460
|
|
| G
|
Cog1
|
component of oligomeric golgi complex 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of COG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:99,192,604...99,207,640
Ensembl chr10:99,194,568...99,208,437
|
|
| G
|
Coil
|
coilin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of COIL protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:74,286,279...74,307,597
Ensembl chr10:74,286,840...74,307,595
|
|
| G
|
Copa
|
COPI coat complex subunit alpha
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of COPA protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:87,078,853...87,119,256
Ensembl chr13:87,078,383...87,119,256
|
|
| G
|
Cope
|
COPI coat complex subunit epsilon
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of COPE protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:19,148,832...19,159,052
Ensembl chr16:19,148,832...19,159,212
|
|
| G
|
Coq6
|
coenzyme Q6 monooxygenase
|
increases expression
|
EXP
|
coumarin results in increased expression of COQ6 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310
|
|
| G
|
Cps1
|
carbamoyl-phosphate synthase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CPS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734
|
|
| G
|
Cpsf7
|
cleavage and polyadenylation specific factor 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CPSF7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:216,592,745...216,616,860
Ensembl chr 1:216,592,463...216,616,855
|
|
| G
|
Cracd
|
capping protein inhibiting regulator of actin dynamics
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CRACD protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:31,638,328...31,874,391
Ensembl chr14:31,638,328...31,683,987
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CREB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Creg1
|
cellular repressor of E1A-stimulated genes 1
|
increases expression
|
EXP
|
coumarin results in increased expression of CREG mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272
|
|
| G
|
Creld2
|
cysteine-rich with EGF-like domains 2
|
increases expression
|
EXP
|
coumarin results in increased expression of CRELD2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:121,788,754...121,796,230
Ensembl chr 7:121,788,745...121,796,228
|
|
| G
|
Cryab
|
crystallin, alpha B
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CRYAB mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
|
|
| G
|
Crybg3
|
crystallin beta-gamma domain containing 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CRYBG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:54,218,399...54,330,962
Ensembl chr11:54,208,444...54,330,960
|
|
| G
|
Cryl1
|
crystallin, lambda 1
|
increases expression
|
EXP
|
coumarin results in increased expression of CRYL1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563
|
|
| G
|
Csad
|
cysteine sulfinic acid decarboxylase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CSAD mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581
|
|
| G
|
Csdc2
|
cold shock domain containing C2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CSDC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:115,332,134...115,346,599
Ensembl chr 7:115,332,128...115,346,596
|
|
| G
|
Csnk1d
|
casein kinase 1, delta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CSNK1D protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953
|
|
| G
|
Cspp1
|
centrosome and spindle pole associated protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CSPP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:13,860,072...13,975,321
|
|
| G
|
Csrp1
|
cysteine and glycine-rich protein 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CSRP1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
|
|
| G
|
Cstf2
|
cleavage stimulation factor subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CSTF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:101,546,809...101,572,760
Ensembl chr X:101,546,819...101,572,764
|
|
| G
|
Ctdspl
|
CTD small phosphatase like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CTDSPL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:127,520,478...127,644,999
Ensembl chr 8:127,520,499...127,644,999
|
|
| G
|
Ctdspl2
|
CTD small phosphatase like 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CTDSPL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:129,368,938...129,424,232
|
|
| G
|
Ctf1
|
cardiotrophin 1
|
increases expression
|
EXP
|
coumarin results in increased expression of CTF1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395
|
|
| G
|
Cth
|
cystathionine gamma-lyase
|
affects expression
|
EXP
|
coumarin affects the expression of CTH mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066
|
|
| G
|
Ctnna1
|
catenin alpha 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CTNNA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of CTNNB1 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Ctnnd1
|
catenin delta 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CTNND1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:90,090,564...90,141,189
|
|
| G
|
Ctps1
|
CTP synthase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CTPS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465
|
|
| G
|
Ctps2
|
CTP synthase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CTPS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505
|
|
| G
|
Ctsb
|
cathepsin B
|
increases expression
|
ISO
|
coumarin analog results in increased expression of CTSB mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
|
|
| G
|
Cttn
|
cortactin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CTTN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211
|
|
| G
|
Cttnbp2nl
|
CTTNBP2 N-terminal like
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CTTNBP2NL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:195,196,318...195,244,792
Ensembl chr 2:195,196,318...195,243,181
|
|
| G
|
Cul4b
|
cullin 4B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CUL4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:122,154,332...122,192,299
Ensembl chr X:122,154,332...122,192,299
|
|
| G
|
Cul7
|
cullin 7
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CUL7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:21,816,703...21,830,344
Ensembl chr 9:21,816,703...21,830,344
|
|
| G
|
Cux1
|
cut-like homeobox 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CUX1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:25,728,393...26,062,497
Ensembl chr12:25,743,733...26,062,497
|
|
| G
|
Cwc22
|
CWC22 spliceosome associated protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of CWC22 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:83,222,400...83,271,427
Ensembl chr 3:83,209,194...83,271,513
|
|
| G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CXCL12 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of CXCR4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cxhxorf38
|
similar to human chromosome X open reading frame 38
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of CXORF38 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:12,800,935...12,823,632
Ensembl chr X:12,802,377...12,814,198
|
|
| G
|
Cyb561
|
cytochrome b-561
|
increases expression
|
EXP
|
coumarin results in increased expression of CYB561 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:91,377,866...91,388,548
Ensembl chr10:91,377,866...91,385,097
|
|
| G
|
Cycs
|
cytochrome c, somatic
|
increases expression
|
ISO
|
coumarin analog results in increased expression of CYCS mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases expression affects expression increases metabolic processing multiple interactions
|
EXP ISO
|
coumarin results in decreased expression of CYP1A2 mRNA coumarin affects the expression of CYP1A2 mRNA CYP1A2 protein results in increased metabolism of coumarin [CYP1A2 protein results in increased metabolism of coumarin] which results in increased abundance of 2-hydroxyphenylacetic acid; [CYP1A2 protein results in increased metabolism of coumarin] which results in increased abundance of 7-hydroxycoumarin
|
CTD |
PMID:16963487 PMID:18480146 PMID:34334558 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Cyp2a1
|
cytochrome P450, family 2, subfamily a, polypeptide 1
|
increases hydroxylation decreases hydroxylation
|
EXP ISO
|
CYP2A6 protein results in increased hydroxylation of coumarin CYP2A13 protein results in increased hydroxylation of coumarin CYP2A13 gene polymorphism results in decreased hydroxylation of coumarin
|
CTD |
PMID:12919726 PMID:17922361 |
|
NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
|
|
| G
|
Cyp2c11
|
cytochrome P450, subfamily 2, polypeptide 11
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CYP2C mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853
|
|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
affects localization multiple interactions increases metabolic processing
|
EXP ISO
|
coumarin affects the localization of CYP2E1 protein [CYP2E1 protein results in increased metabolism of coumarin] which results in increased abundance of 2-hydroxyphenylacetic acid
|
CTD |
PMID:28803882 PMID:34334558 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
affects expression
|
EXP
|
coumarin affects the expression of CYP3A2 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Cyp51
|
cytochrome P450, family 51
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CYP51 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450
|
|
| G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of CYP7A1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
|
|
| G
|
Dab2ip
|
DAB2 interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DAB2IP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730
|
|
| G
|
Dap
|
death-associated protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:83,910,060...83,962,673
|
|
| G
|
Dapk1
|
death associated protein kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DAPK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581
|
|
| G
|
Dapk3
|
death-associated protein kinase 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DAPK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:9,174,904...9,183,272
|
|
| G
|
Daxx
|
death-domain associated protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DAXX protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720
|
|
| G
|
Dbn1
|
drebrin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DBN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122
|
|
| G
|
Dbnl
|
drebrin-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DBNL protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:84,880,085...84,895,122
Ensembl chr14:84,880,142...84,897,133
|
|
| G
|
Dbt
|
dihydrolipoamide branched chain transacylase E2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DBT protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525
|
|
| G
|
Dcaf10
|
DDB1 and CUL4 associated factor 10
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DCAF10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:64,402,307...64,442,839
Ensembl chr 5:64,403,451...64,440,614
|
|
| G
|
Dcaf12
|
DDB1 and CUL4 associated factor 12
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DCAF12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:61,256,353...61,278,155
Ensembl chr 5:61,256,353...61,278,119
|
|
| G
|
Dcaf6
|
DDB1 and CUL4 associated factor 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DCAF6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:80,159,282...80,260,510
Ensembl chr13:80,159,321...80,260,510
|
|
| G
|
Dcbld2
|
discoidin, CUB and LCCL domain containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DCBLD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:55,594,691...55,649,113
Ensembl chr11:55,594,691...55,649,085
|
|
| G
|
Dcp1a
|
decapping mRNA 1A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DCP1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:5,663,437...5,708,623
Ensembl chr16:5,663,203...5,708,618
|
|
| G
|
Dcp2
|
decapping mRNA 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DCP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:37,001,615...37,037,949
Ensembl chr18:37,001,615...37,049,939
|
|
| G
|
Ddit4l
|
DNA-damage-inducible transcript 4-like
|
increases expression
|
EXP
|
coumarin results in increased expression of DDIT4L mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
|
|
| G
|
Ddost
|
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
|
increases expression
|
EXP
|
coumarin results in increased expression of DDOST mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:155,805,612...155,812,728
Ensembl chr 5:155,805,454...155,813,121
|
|
| G
|
Ddx10
|
DEAD-box helicase 10
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DDX10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:62,384,876...62,539,585
Ensembl chr 8:62,384,876...62,539,585
|
|
| G
|
Ddx17
|
DEAD-box helicase 17
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DDX17 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747
|
|
| G
|
Ddx20
|
DEAD-box helicase 20
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DDX20 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:195,847,105...195,859,989
Ensembl chr 2:195,847,105...195,855,461
|
|
| G
|
Ddx21
|
DExD-box helicase 21
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DDX21 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
|
|
| G
|
Ddx24
|
DEAD-box helicase 24
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DDX24 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:128,329,554...128,349,625
|
|
| G
|
Ddx31
|
DEAD-box helicase 31
|
decreases expression decreases phosphorylation
|
EXP ISO
|
coumarin results in decreased expression of DDX31 mRNA coumarin results in decreased phosphorylation of DDX31 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr 3:32,570,725...32,635,446
Ensembl chr 3:32,571,020...32,636,954
|
|
| G
|
Ddx42
|
DEAD-box helicase 42
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DDX42 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:91,648,719...91,680,730
Ensembl chr10:91,648,248...91,680,729
|
|
| G
|
Ddx46
|
DEAD-box helicase 46
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DDX46 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:8,947,237...8,993,705
Ensembl chr17:8,947,237...8,990,247
|
|
| G
|
Ddx50
|
DExD-box helicase 50
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DDX50 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:31,104,354...31,133,652
Ensembl chr20:31,104,354...31,133,652
|
|
| G
|
Ddx54
|
DEAD-box helicase 54
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DDX54 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:41,595,298...41,610,560
Ensembl chr12:41,595,555...41,611,053
|
|
| G
|
Ddx59
|
DEAD-box helicase 59
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DDX59 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:50,427,940...50,452,893
Ensembl chr13:50,427,936...50,453,208
|
|
| G
|
Deaf1
|
DEAF1 transcription factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DEAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:205,831,428...205,865,106
Ensembl chr 1:205,831,336...205,865,106
|
|
| G
|
Defb17
|
defensin beta 17
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DEFB110 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:28,376,792...28,380,421
Ensembl chr 9:28,376,792...28,380,421
|
|
| G
|
Dek
|
DEK proto-oncogene
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DEK protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122
|
|
| G
|
Dennd3
|
DENN domain containing 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DENND3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:107,304,860...107,362,573
Ensembl chr 7:107,220,192...107,362,573
|
|
| G
|
Dennd4a
|
DENN domain containing 4A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DENND4A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:74,218,131...74,331,543
Ensembl chr 8:74,218,191...74,331,542
|
|
| G
|
Dennd4c
|
DENN domain containing 4C
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DENND4C protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:106,316,942...106,421,484
Ensembl chr 5:106,318,281...106,415,489
|
|
| G
|
Desi2
|
desumoylating isopeptidase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DESI2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981
|
|
| G
|
Dhx36
|
DEAH-box helicase 36
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DHX36 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:149,006,089...149,044,192
Ensembl chr 2:149,006,089...149,044,191
|
|
| G
|
Dido1
|
death inducer-obliterator 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DIDO1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,150,100...188,203,445
Ensembl chr 3:188,150,100...188,194,823
|
|
| G
|
Dip2b
|
disco-interacting protein 2 homolog B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DIP2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:133,053,393...133,231,430
Ensembl chr 7:133,053,401...133,228,874
|
|
| G
|
Dis3l2
|
DIS3-like 3'-5' exoribonuclease 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DIS3L2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:94,802,056...95,184,523
Ensembl chr 9:94,804,382...95,184,522
|
|
| G
|
Dixdc1
|
DIX domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DIXDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:59,904,218...59,977,595
Ensembl chr 8:59,904,218...59,978,447
|
|
| G
|
Dlg1
|
discs large MAGUK scaffold protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DLG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797
|
|
| G
|
Dlg5
|
discs large MAGUK scaffold protein 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DLG5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:125,287...237,334
Ensembl chr15:125,290...237,332
|
|
| G
|
Dlgap5
|
DLG associated protein 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DLGAP5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176
|
|
| G
|
Dmap1
|
DNA methyltransferase 1-associated protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DMAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:136,380,211...136,388,229
Ensembl chr 5:136,380,216...136,388,219
|
|
| G
|
Dmd
|
dystrophin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DMD protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835
|
|
| G
|
Dmwd
|
DM1 locus, WD repeat containing
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DMWD protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:87,850,475...87,857,263
Ensembl chr 1:87,850,604...87,857,624
|
|
| G
|
Dmxl2
|
Dmx-like 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DMXL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:63,637,314...63,803,911
Ensembl chr 8:63,637,314...63,781,116
|
|
| G
|
Dnah10
|
dynein, axonemal, heavy chain 10
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAH10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860
|
|
| G
|
Dnah7
|
dynein, axonemal, heavy chain 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAH7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:62,454,838...62,760,504
Ensembl chr 9:62,454,838...62,756,730
|
|
| G
|
Dnah9
|
dynein, axonemal, heavy chain 9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAH9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:50,996,796...51,363,977
Ensembl chr10:50,996,796...51,363,963
|
|
| G
|
Dnajb11
|
DnaJ heat shock protein family (Hsp40) member B11
|
increases expression
|
EXP
|
coumarin results in increased expression of DNAJB11 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800
|
|
| G
|
Dnajb6
|
DnaJ heat shock protein family (Hsp40) member B6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAJB6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:6,128,070...6,232,005
|
|
| G
|
Dnajb7
|
DnaJ heat shock protein family (Hsp40) member B7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAJB7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:114,812,886...114,814,200
Ensembl chr 7:114,810,853...114,814,405
|
|
| G
|
Dnajb9
|
DnaJ heat shock protein family (Hsp40) member B9
|
affects expression
|
EXP
|
coumarin affects the expression of DNAJB9 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
|
|
| G
|
Dnajc1
|
DnaJ heat shock protein family (Hsp40) member C1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DNAJC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:85,863,651...86,020,954
Ensembl chr17:85,863,651...86,020,432
|
|
| G
|
Dnajc27
|
DnaJ heat shock protein family (Hsp40) member C27
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DNAJC27 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:32,788,215...32,842,418
Ensembl chr 6:32,788,184...32,817,940
|
|
| G
|
Dnajc3
|
DnaJ heat shock protein family (Hsp40) member C3
|
increases expression
|
EXP
|
coumarin results in increased expression of DNAJC3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
|
|
| G
|
Dnajc5
|
DnaJ heat shock protein family (Hsp40) member C5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DNAJC5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,999,508...189,033,455
Ensembl chr 3:188,999,470...189,034,089
|
|
| G
|
Dnajc6
|
DnaJ heat shock protein family (Hsp40) member C6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAJC6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:121,232,532...121,398,775
Ensembl chr 5:121,235,425...121,398,775
|
|
| G
|
Dnajc9
|
DnaJ heat shock protein family (Hsp40) member C9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNAJC9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,970,114...3,977,304
|
|
| G
|
Dnmt1
|
DNA methyltransferase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DNMT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
|
|
| G
|
Dnmt3a
|
DNA methyltransferase 3 alpha
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DNMT3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
|
|
| G
|
Dnttip2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DNTTIP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:213,058,975...213,071,020
Ensembl chr 2:213,058,962...213,071,016
|
|
| G
|
Dok1
|
docking protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DOK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:117,095,171...117,098,251
Ensembl chr 4:117,095,175...117,097,825
|
|
| G
|
Dot1l
|
DOT1 like histone lysine methyltransferase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DOT1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,569,439...9,607,095
Ensembl chr 7:9,569,439...9,607,095
|
|
| G
|
Dpf2
|
double PHD fingers 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DPF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,612,986...212,628,376
Ensembl chr 1:212,612,986...212,628,289
|
|
| G
|
Dpysl2
|
dihydropyrimidinase-like 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DPYSL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065
|
|
| G
|
Drosha
|
drosha ribonuclease III
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DROSHA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:63,591,968...63,703,687
|
|
| G
|
Dscc1
|
DNA replication and sister chromatid cohesion 1
|
increases expression
|
EXP
|
coumarin results in increased expression of DSCC1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:88,372,349...88,390,815
Ensembl chr 7:88,372,146...88,387,973
|
|
| G
|
Dsn1
|
DSN1 component of MIS12 kinetochore complex
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DSN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:166,072,775...166,089,029
Ensembl chr 3:166,074,033...166,085,890
|
|
| G
|
Dsp
|
desmoplakin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DSP protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,829,153...26,877,121
|
|
| G
|
Dst
|
dystonin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of DST protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
|
|
| G
|
Dtl
|
denticleless E3 ubiquitin protein ligase homolog
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DTL protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174
|
|
| G
|
Dtnbp1
|
dystrobrevin binding protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DTNBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:19,891,313...19,982,770
Ensembl chr17:19,891,337...19,984,418
|
|
| G
|
Dus3l
|
dihydrouridine synthase 3-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DUS3L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,680,619...1,685,784
Ensembl chr 9:1,675,819...1,686,367
|
|
| G
|
Dut
|
deoxyuridine triphosphatase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DUT protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956
|
|
| G
|
Dync1i2
|
dynein cytoplasmic 1 intermediate chain 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DYNC1I2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:76,441,621...76,492,782
Ensembl chr 3:76,424,469...76,492,782
|
|
| G
|
Dync1li1
|
dynein cytoplasmic 1 light intermediate chain 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of DYNC1LI1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:123,254,823...123,288,496
Ensembl chr 8:123,254,859...123,289,167
|
|
| G
|
Dyrk1a
|
dual specificity tyrosine phosphorylation regulated kinase 1A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DYRK1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:47,360,824...47,479,033
Ensembl chr11:47,360,850...47,479,033
|
|
| G
|
Dzip3
|
DAZ interacting zinc finger protein 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of DZIP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:65,286,190...65,356,314
Ensembl chr11:65,286,190...65,356,314
|
|
| G
|
Eapp
|
E2F-associated phosphoprotein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EAPP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:77,879,634...77,929,653
Ensembl chr 6:77,907,485...77,928,930
|
|
| G
|
Eci1
|
enoyl-CoA delta isomerase 1
|
affects expression
|
EXP
|
coumarin affects the expression of ECI1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
|
|
| G
|
Edc3
|
enhancer of mRNA decapping 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EDC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:67,002,032...67,047,563
Ensembl chr 8:67,002,014...67,047,559
|
|
| G
|
Edc4
|
enhancer of mRNA decapping 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EDC4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:50,683,924...50,695,916
Ensembl chr19:50,683,897...50,697,620
|
|
| G
|
Eef1akmt2
|
EEF1A lysine methyltransferase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EEF1AKMT2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:197,009,919...197,071,033
Ensembl chr 1:197,046,930...197,071,013
|
|
| G
|
Eef1d
|
eukaryotic translation elongation factor 1 delta
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EEF1D protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531
|
|
| G
|
Eef1e1
|
eukaryotic translation elongation factor 1 epsilon 1
|
increases expression
|
EXP
|
coumarin results in increased expression of EEF1E1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687
|
|
| G
|
Eef2
|
eukaryotic translation elongation factor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EEF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EGFR protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Ehbp1
|
EH domain binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EHBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579
|
|
| G
|
Ehd2
|
EH-domain containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EHD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943
|
|
| G
|
Ehd4
|
EH-domain containing 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EHD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:127,511,954...127,576,072
|
|
| G
|
Eif2a
|
eukaryotic translation initiation factor 2A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EIF2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
|
|
| G
|
Eif2ak1
|
eukaryotic translation initiation factor 2 alpha kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF2AK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281
|
|
| G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF2AK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
|
|
| G
|
Eif2s2
|
eukaryotic translation initiation factor 2 subunit beta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF2S2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570
|
|
| G
|
Eif3a
|
eukaryotic translation initiation factor 3, subunit A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:269,888,730...269,925,785
Ensembl chr 1:269,888,615...269,919,025
|
|
| G
|
Eif3c
|
eukaryotic translation initiation factor 3, subunit C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF3C protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067
|
|
| G
|
Eif3k
|
eukaryotic translation initiation factor 3, subunit K
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EIF3K protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:93,387,628...93,397,551
Ensembl chr 1:93,387,628...93,397,802
|
|
| G
|
Eif4a3
|
eukaryotic translation initiation factor 4A3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF4A3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:105,047,567...105,057,561
Ensembl chr10:105,047,568...105,058,207
|
|
| G
|
Eif4b
|
eukaryotic translation initiation factor 4B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EIF4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EIF4EBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
|
|
| G
|
Eif4g1
|
eukaryotic translation initiation factor 4 gamma 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EIF4G1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367
|
|
| G
|
Eif4g3
|
eukaryotic translation initiation factor 4 gamma, 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EIF4G3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:155,481,378...155,702,194
Ensembl chr 5:155,481,378...155,702,194
|
|
| G
|
Eif5b
|
eukaryotic translation initiation factor 5B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EIF5B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:47,718,706...47,773,289
Ensembl chr 9:47,718,706...47,778,583
|
|
| G
|
Elac2
|
elaC ribonuclease Z 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ELAC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069
|
|
| G
|
Elf1
|
E74 like ETS transcription factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ELF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:61,354,026...61,395,762
Ensembl chr15:61,330,877...61,395,758
|
|
| G
|
Elf2
|
E74 like ETS transcription factor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ELF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:137,445,787...137,536,512
Ensembl chr 2:137,445,788...137,470,355
|
|
| G
|
Ell3
|
elongation factor for RNA polymerase II 3
|
increases expression
|
EXP
|
coumarin results in increased expression of ELL3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:128,864,777...128,870,852
|
|
| G
|
Eloa
|
elongin A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ELOA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:153,513,246...153,530,819
Ensembl chr 5:153,515,066...153,530,916
|
|
| G
|
Elp1
|
elongator acetyltransferase complex subunit 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ELP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:76,248,545...76,300,985
Ensembl chr 5:76,248,550...76,300,985
|
|
| G
|
Emd
|
emerin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EMD protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:157,190,438...157,193,479
Ensembl chr X:157,189,819...157,197,095
|
|
| G
|
Eme1
|
essential meiotic structure-specific endonuclease 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EME1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:80,083,585...80,092,450
Ensembl chr10:80,083,585...80,092,301
|
|
| G
|
Eme2
|
essential meiotic structure-specific endonuclease subunit 2
|
increases expression
|
EXP
|
coumarin results in increased expression of EME2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:14,413,661...14,420,489
Ensembl chr10:14,417,735...14,420,489
|
|
| G
|
Eml4
|
EMAP like 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EML4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439
|
|
| G
|
Eml5
|
EMAP like 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EML5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:123,775,269...123,905,585
Ensembl chr 6:123,776,368...123,905,538
|
|
| G
|
Emsy
|
EMSY transcriptional repressor, BRCA2 interacting
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EMSY protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:162,295,167...162,364,742
Ensembl chr 1:162,295,169...162,364,707
|
|
| G
|
Ensa
|
endosulfine alpha
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ENSA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:185,874,500...185,881,838
Ensembl chr 2:185,874,500...185,881,838
|
|
| G
|
Entr1
|
endosome associated trafficking regulator 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ENTR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:29,599,059...29,605,780
Ensembl chr 3:29,599,059...29,605,898
|
|
| G
|
Ep300
|
E1A binding protein p300
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EP300 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
|
|
| G
|
Ep400
|
E1A binding protein p400
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EP400 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:51,551,665...51,658,635
Ensembl chr12:51,551,695...51,658,634
|
|
| G
|
Epb41
|
erythrocyte membrane protein band 4.1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of EPB41 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:149,394,080...149,548,178
Ensembl chr 5:149,394,096...149,543,540
|
|
| G
|
Epb41l1
|
erythrocyte membrane protein band 4.1-like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EPB41L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:165,389,295...165,512,821
Ensembl chr 3:165,389,293...165,510,498
|
|
| G
|
Epb41l2
|
erythrocyte membrane protein band 4.1-like 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EPB41L2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:21,682,335...21,857,105
|
|
| G
|
Epb41l5
|
erythrocyte membrane protein band 4.1 like 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EPB41L5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
increases expression
|
ISO
|
coumarin results in increased expression of EPHX1 mRNA
|
CTD |
PMID:17311802 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Eppk1
|
epiplakin 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EPPK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468
|
|
| G
|
Eprs1
|
glutamyl-prolyl-tRNA synthetase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EPRS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509
|
|
| G
|
Eps15l1
|
epidermal growth factor receptor pathway substrate 15-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EPS15L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:17,460,330...17,573,824
Ensembl chr16:17,460,465...17,535,703
|
|
| G
|
Eral1
|
Era-like 12S mitochondrial rRNA chaperone 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ERAL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,459,774...63,466,829
Ensembl chr10:63,459,774...63,468,225
|
|
| G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ERBB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
|
|
| G
|
Erbin
|
erbb2 interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ERBIN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:36,660,399...36,762,584
Ensembl chr 2:36,660,399...36,762,153
|
|
| G
|
Ercc4
|
ERCC excision repair 4, endonuclease catalytic subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ERCC4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539
|
|
| G
|
Ercc5
|
ERCC excision repair 5, endonuclease
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ERCC5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084
|
|
| G
|
Ercc6l
|
ERCC excision repair 6 like, spindle assembly checkpoint helicase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ERCC6L protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:71,285,380...71,301,186
Ensembl chr X:71,285,380...71,301,186
|
|
| G
|
Erf
|
Ets2 repressor factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ERF protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:89,957,760...89,966,213
|
|
| G
|
Esco2
|
establishment of sister chromatid cohesion N-acetyltransferase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ESCO2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304 Ensembl chr15:44,210,641...44,231,304
|
|
| G
|
Esf1
|
ESF1 nucleolar pre-rRNA processing protein homolog
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ESF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:147,908,405...147,961,567
Ensembl chr 3:147,908,405...147,961,485
|
|
| G
|
Ess2
|
ess-2 splicing factor homolog
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ESS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:96,580,185...96,596,673
Ensembl chr11:96,580,169...96,590,146
|
|
| G
|
Esyt2
|
extended synaptotagmin 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ESYT2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:143,359,870...143,455,600
Ensembl chr 6:143,362,694...143,455,593
|
|
| G
|
Etl4
|
enhancer trap locus 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KIAA1217 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:87,749,486...88,213,158
Ensembl chr17:87,403,819...88,213,158
|
|
| G
|
Etv3
|
ETS variant transcription factor 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ETV3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:175,263,389...175,278,217
Ensembl chr 2:175,263,459...175,278,208
|
|
| G
|
Etv5
|
ETS variant transcription factor 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ETV5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:92,113,171...92,170,758
Ensembl chr11:92,113,224...92,170,767
|
|
| G
|
Etv6
|
ETS variant transcription factor 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ETV6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:168,580,138...168,819,802
|
|
| G
|
Exo1
|
exonuclease 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of EXO1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861
|
|
| G
|
Exosc1
|
exosome component 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EXOSC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:250,684,746...250,694,748
Ensembl chr 1:250,684,750...250,694,748
|
|
| G
|
Ezh2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of EZH2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
|
|
| G
|
F9
|
coagulation factor IX
|
increases response to substance
|
ISO
|
F9 exon polymorphism results in increased susceptibility to coumarin; F9 protein mutant form results in increased susceptibility to coumarin
|
CTD |
PMID:11307814 |
|
NCBI chr X:143,388,642...143,433,143
Ensembl chr X:143,388,621...143,433,146
|
|
| G
|
Fadd
|
Fas associated via death domain
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FADD protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
|
|
| G
|
Fads1
|
fatty acid desaturase 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of FADS1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615
|
|
| G
|
Faf1
|
Fas associated factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:129,654,445...130,020,516
|
|
| G
|
Fam111a
|
FAM111 trypsin like peptidase A
|
increases expression
|
EXP
|
coumarin results in increased expression of FAM111A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:219,065,542...219,081,213
Ensembl chr 1:219,065,601...219,081,211
|
|
| G
|
Fam117b
|
family with sequence similarity 117, member B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM117B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:68,834,354...68,902,543
|
|
| G
|
Fam168b
|
family with sequence similarity 168, member B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM168B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:44,501,466...44,534,571
Ensembl chr 9:44,502,584...44,534,974
|
|
| G
|
Fam169a
|
family with sequence similarity 169, member A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FAM169A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:30,115,307...30,175,972
Ensembl chr 2:30,119,381...30,175,962
|
|
| G
|
Fam177a1
|
family with sequence similarity 177, member A1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM177A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:78,367,780...78,382,703
Ensembl chr 6:78,367,780...78,392,836
|
|
| G
|
Fam193a
|
family with sequence similarity 193, member A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM193A protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:80,480,742...80,607,086
Ensembl chr14:80,480,742...80,607,024
|
|
| G
|
Fam193b
|
family with sequence similarity 193, member B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM193B protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:9,071,974...9,104,659
Ensembl chr17:9,071,795...9,104,656
|
|
| G
|
Fam219a
|
family with sequence similarity 219, member A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM219A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:61,475,185...61,525,749
Ensembl chr 5:61,475,185...61,525,749
|
|
| G
|
Fam219b
|
family with sequence similarity 219, member B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FAM219B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:66,837,230...66,842,819
Ensembl chr 8:66,837,205...66,842,819
|
|
| G
|
Fam234b
|
family with sequence similarity 234, member B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of FAM234B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:169,779,651...169,854,024
Ensembl chr 4:169,779,737...169,828,678
|
|
| G
|
Fam53c
|
family with sequence similarity 53, member C
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FAM53C protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:26,638,781...26,652,294
Ensembl chr18:26,638,062...26,652,290
|
|
| G
|
Fam83b
|
family with sequence similarity 83, member B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FAM83B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:86,167,778...86,244,222
Ensembl chr 8:86,167,778...86,244,222
|
|
| G
|
Fam83h
|
family with sequence similarity 83, member H
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of FAM83H protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:109,597,129...109,605,317
Ensembl chr 7:109,597,129...109,609,188
|
|
| G
|
Fam91a1
|
family with sequence similarity 91, member A1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FAM91A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:91,857,261...91,897,019
Ensembl chr 7:91,859,062...91,898,195
|
|
| G
|
Fancd2
|
FA complementation group D2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FANCD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035
|
|
| G
|
Fance
|
FA complementation group E
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FANCE protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:6,371,153...6,388,366
Ensembl chr20:6,377,234...6,388,365
|
|
| G
|
Fanci
|
FA complementation group I
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FANCI protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:142,736,653...142,792,999
|
|
| G
|
Fancm
|
FA complementation group M
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FANCM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:88,862,898...88,916,701
Ensembl chr 6:88,863,306...88,921,652
|
|
| G
|
Farp1
|
FERM, ARH/RhoGEF and pleckstrin domain protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FARP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147
|
|
| G
|
Fasn
|
fatty acid synthase
|
affects expression
|
EXP
|
coumarin affects the expression of FASN mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
|
Fat4
|
FAT atypical cadherin 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FAT4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:123,855,289...123,984,716
Ensembl chr 2:123,855,289...123,984,716
|
|
| G
|
Fbh1
|
F-box DNA helicase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FBH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:71,659,351...71,697,431
Ensembl chr17:71,659,249...71,697,432
|
|
| G
|
Fbxo42
|
F-box protein 42
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FBXO42 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:158,734,165...158,792,560
Ensembl chr 5:158,734,175...158,792,565
|
|
| G
|
Fcho2
|
FCH and mu domain containing endocytic adaptor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of FCHO2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:31,813,356...31,916,471
Ensembl chr 2:31,814,950...31,915,445
|
|
| G
|
Fen1
|
flap structure-specific endonuclease 1
|
increases expression
|
EXP
|
coumarin results in increased expression of FEN1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
|
|
| G
|
Fermt2
|
FERM domain containing kindlin 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of FERMT2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:21,162,603...21,257,995
Ensembl chr15:21,162,605...21,258,115
|
|
| G
|
Fez2
|
fasciculation and elongation protein zeta 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FEZ2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:22,406,685...22,446,745
Ensembl chr 6:22,406,632...22,447,041
|
|
| G
|
Fgd1
|
FYVE, RhoGEF and PH domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FGD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:23,466,791...23,509,773
Ensembl chr X:23,467,530...23,509,979
|
|
| G
|
Fgf7
|
fibroblast growth factor 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FGF7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
|
|
| G
|
Fgfr4
|
fibroblast growth factor receptor 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FGFR4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389
|
|
| G
|
Fgg
|
fibrinogen gamma chain
|
affects expression
|
EXP
|
coumarin affects the expression of FGG mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
|
|
| G
|
Fggy
|
FGGY carbohydrate kinase domain containing
|
decreases expression
|
EXP
|
coumarin results in decreased expression of FGGY mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:115,514,573...115,901,713
Ensembl chr 5:115,472,211...115,901,714
|
|
| G
|
Fhod1
|
formin homology 2 domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FHOD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:50,116,415...50,135,868
Ensembl chr19:50,116,415...50,135,330
|
|
| G
|
Fip1l1
|
factor interacting with PAPOLA and CPSF1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of FIP1L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:33,969,341...34,030,871
Ensembl chr14:33,971,914...34,029,753
|
|
| G
|
Fkbp11
|
FKBP prolyl isomerase 11
|
increases expression
|
EXP
|
coumarin results in increased expression of FKBP11 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123
|
|
| G
|
Fkbp15
|
FKBP prolyl isomerase family member 15
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of FKBP15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:80,766,356...80,830,622
Ensembl chr 5:80,766,356...80,830,565
|
|
| G
|
Fkbp3
|
FKBP prolyl isomerase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FKBP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:88,850,137...88,862,542
Ensembl chr 6:88,843,879...88,863,447
|
|
| G
|
Fkbp4
|
FKBP prolyl isomerase 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FKBP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918
|
|
| G
|
Flcn
|
folliculin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FLCN protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309
|
|
| G
|
Flna
|
filamin A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FLNA protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343
|
|
| G
|
Flot1
|
flotillin 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FLOT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771
|
|
| G
|
Fmo1
|
flavin containing dimethylaniline monoxygenase 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of FMO1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
|
|
| G
|
Fnbp1
|
formin binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FNBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:34,706,814...34,826,770
Ensembl chr 3:34,706,814...34,822,117
|
|
| G
|
Fnbp1l
|
formin binding protein 1-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FNBP1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:213,331,871...213,432,821
Ensembl chr 2:213,318,662...213,423,051
|
|
| G
|
Fnbp4
|
formin binding protein 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FNBP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:97,188,852...97,218,916
Ensembl chr 3:97,188,884...97,219,435
|
|
| G
|
Fnip1
|
folliculin interacting protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FNIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:39,068,432...39,151,552
Ensembl chr10:39,068,445...39,151,552
|
|
| G
|
Fnta
|
farnesyltransferase, CAAX box, subunit alpha
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FNTA protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:72,767,864...72,786,193
Ensembl chr16:72,767,627...72,788,229
|
|
| G
|
Fosl2
|
FOS like 2, AP-1 transcription factor subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FOSL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406
|
|
| G
|
Foxa1
|
forkhead box A1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FOXA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
|
|
| G
|
Foxc1
|
forkhead box C1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FOXC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347
|
|
| G
|
Foxf1
|
forkhead box F1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FOXF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:66,062,635...66,066,427
Ensembl chr19:66,062,369...66,066,428
|
|
| G
|
Foxj3
|
forkhead box J3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FOXJ3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:138,425,623...138,513,760
Ensembl chr 5:138,424,923...138,513,760
|
|
| G
|
Foxk1
|
forkhead box K1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FOXK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:17,223,599...17,288,564
Ensembl chr12:17,229,430...17,288,564
|
|
| G
|
Foxk2
|
forkhead box K2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FOXK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:107,040,933...107,090,860
Ensembl chr10:107,040,933...107,195,823
|
|
| G
|
Foxm1
|
forkhead box M1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FOXM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
|
|
| G
|
Foxn3
|
forkhead box N3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FOXN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040
|
|
| G
|
Foxo3
|
forkhead box O3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FOXO3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
|
|
| G
|
Foxp2
|
forkhead box P2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FOXP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:44,099,959...44,677,696
|
|
| G
|
Foxp4
|
forkhead box P4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FOXP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:20,556,270...20,612,967
Ensembl chr 9:20,556,270...20,612,967
|
|
| G
|
Fra10ac1
|
FRA10A associated CGG repeat 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FRA10AC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:245,381,538...245,413,879
Ensembl chr 1:245,366,451...245,414,189
|
|
| G
|
Frs2
|
fibroblast growth factor receptor substrate 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FRS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:54,597,182...54,678,656
Ensembl chr 7:54,597,182...54,678,774
|
|
| G
|
Fto
|
FTO, alpha-ketoglutarate dependent dioxygenase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FTO protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:31,456,749...31,865,011
Ensembl chr19:31,522,293...31,864,957
|
|
| G
|
Ftsj3
|
FtsJ RNA 2'-O-methyltransferase 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FTSJ3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:91,680,735...91,687,475
Ensembl chr10:91,680,753...91,687,179
|
|
| G
|
Fubp1
|
far upstream element binding protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FUBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428
|
|
| G
|
Fus
|
Fus RNA binding protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FUS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884
|
|
| G
|
Fxr1
|
FMR1 autosomal homolog 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FXR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:118,811,980...118,867,027
|
|
| G
|
Fxr2
|
FMR1 autosomal homolog 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of FXR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:54,849,345...54,869,713
Ensembl chr10:54,849,267...54,869,713
|
|
| G
|
Fzd6
|
frizzled class receptor 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of FZD6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680
|
|
| G
|
G3bp2
|
G3BP stress granule assembly factor 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of G3BP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:16,216,684...16,304,828
Ensembl chr14:16,248,744...16,304,823
|
|
| G
|
Gaa
|
alpha glucosidase
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GAA protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:105,028,106...105,045,365
Ensembl chr10:105,028,307...105,045,366
|
|
| G
|
Gab1
|
GRB2-associated binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GAB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:44,035,693...44,143,617
Ensembl chr19:44,035,063...44,143,617
|
|
| G
|
Gapdh
|
glyceraldehyde-3-phosphate dehydrogenase
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GAPDH protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
|
|
| G
|
Gas5
|
growth arrest specific 5
|
increases expression
|
EXP
|
coumarin results in increased expression of GAS5 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:75,836,963...75,840,284
|
|
| G
|
Gatad2a
|
GATA zinc finger domain containing 2A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GATAD2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:19,463,500...19,553,497
Ensembl chr16:19,463,500...19,553,497
|
|
| G
|
Gbf1
|
golgi brefeldin A resistant guanine nucleotide exchange factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GBF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:254,959,784...255,088,479
Ensembl chr 1:254,960,001...255,088,471
|
|
| G
|
Gckr
|
glucokinase regulator
|
decreases expression
|
EXP
|
coumarin results in decreased expression of GCKR mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
increases expression
|
EXP
|
coumarin results in increased expression of GCLC mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
increases expression
|
EXP
|
coumarin results in increased expression of GCLM mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
|
|
| G
|
Gdap1
|
ganglioside-induced differentiation-associated-protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GDAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:6,715,935...6,735,013
Ensembl chr 5:6,715,935...6,735,313
|
|
| G
|
Gemin5
|
gem (nuclear organelle) associated protein 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GEMIN5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:42,797,975...42,843,356
Ensembl chr10:42,797,982...42,843,356
|
|
| G
|
Ggnbp2
|
gametogenetin binding protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GGNBP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:70,208,950...70,240,554
Ensembl chr10:70,208,950...70,246,260
|
|
| G
|
Gins2
|
GINS complex subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GINS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:65,535,492...65,548,270
Ensembl chr19:65,535,492...65,548,052
|
|
| G
|
Git1
|
GIT ArfGAP 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GIT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:62,840,165...62,854,508
Ensembl chr10:62,840,394...62,854,508
|
|
| G
|
Git2
|
GIT ArfGAP 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GIT2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:47,490,350...47,531,232
Ensembl chr12:47,490,369...47,533,250
|
|
| G
|
Gjb2
|
gap junction protein, beta 2
|
increases expression
|
EXP
|
coumarin results in increased expression of GJB2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877
|
|
| G
|
Gk
|
glycerol kinase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of GK mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr X:54,106,708...54,189,940
Ensembl chr X:54,112,214...54,196,701
|
|
| G
|
Glb1
|
galactosidase, beta 1
|
increases expression
|
EXP
|
coumarin results in increased expression of GLB1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
|
|
| G
|
Gldc
|
glycine decarboxylase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of GLDC mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604
|
|
| G
|
Glis2
|
GLIS family zinc finger 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GLIS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:11,457,594...11,484,948
Ensembl chr10:11,457,792...11,477,995
|
|
| G
|
Glyr1
|
glyoxylate reductase 1 homolog
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GLYR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:11,038,577...11,074,093
Ensembl chr10:11,038,568...11,074,090
|
|
| G
|
Gmeb2
|
glucocorticoid modulatory element binding protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GMEB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,740,210...188,778,377
Ensembl chr 3:188,740,210...188,778,336
|
|
| G
|
Gmip
|
Gem-interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GMIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:19,634,630...19,648,916
Ensembl chr16:19,634,630...19,647,933
|
|
| G
|
Gmnn
|
geminin, DNA replication inhibitor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GMNN protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,729,824...40,738,068
|
|
| G
|
Gmps
|
guanine monophosphate synthase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GMPS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986
|
|
| G
|
Gnl1
|
G protein nucleolar 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GNL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:2,787,939...2,796,924
Ensembl chr20:2,787,940...2,797,577
|
|
| G
|
Golga3
|
golgin A3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GOLGA3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:52,112,129...52,160,311
Ensembl chr12:52,114,590...52,160,226
|
|
| G
|
Gorasp1
|
golgi reassembly stacking protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GORASP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:128,532,933...128,544,686
Ensembl chr 8:128,532,934...128,544,636
|
|
| G
|
Gorasp2
|
golgi reassembly stacking protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GORASP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:75,882,607...75,911,322
Ensembl chr 3:75,882,515...75,911,328
|
|
| G
|
Gpam
|
glycerol-3-phosphate acyltransferase, mitochondrial
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GPAM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911
|
|
| G
|
Gpatch4
|
G patch domain containing 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GPATCH4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:175,797,503...175,816,547
Ensembl chr 2:175,807,682...175,817,358
|
|
| G
|
Gphn
|
gephyrin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GPHN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:102,687,423...103,216,674
|
|
| G
|
Gpr108
|
G protein-coupled receptor 108
|
decreases expression
|
EXP
|
coumarin results in decreased expression of GPR108 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 9:2,207,716...2,218,738
Ensembl chr 9:2,207,726...2,219,750
|
|
| G
|
Gprin1
|
G protein-regulated inducer of neurite outgrowth 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GPRIN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:9,869,009...9,881,958
Ensembl chr17:9,868,571...9,894,560
|
|
| G
|
Gpx1
|
glutathione peroxidase 1
|
affects expression
|
EXP
|
coumarin affects the expression of GPX1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
| G
|
Gramd1a
|
GRAM domain containing 1A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GRAMD1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:95,494,378...95,520,730
Ensembl chr 1:95,494,378...95,520,716
|
|
| G
|
Gramd1b
|
GRAM domain containing 1B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GRAMD1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:49,551,642...49,790,965
Ensembl chr 8:49,556,332...49,791,052
|
|
| G
|
Grip1
|
glutamate receptor interacting protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GRIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:56,820,501...57,477,877
Ensembl chr 7:56,820,704...57,468,417
|
|
| G
|
Gse1
|
Gse1 coiled-coil protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GSE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:65,182,678...65,538,183
Ensembl chr19:65,446,263...65,538,176
|
|
| G
|
Gsk3a
|
glycogen synthase kinase 3 alpha
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GSK3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:89,943,669...89,953,593
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GSK3B protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
increases expression
|
EXP
|
coumarin results in increased expression of GSR mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Gsta2
|
glutathione S-transferase alpha 2
|
increases expression
|
ISO
|
coumarin results in increased expression of GSTA2 protein
|
CTD |
PMID:11309284 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
|
|
| G
|
Gsta3
|
glutathione S-transferase alpha 3
|
increases expression
|
EXP
|
coumarin results in increased expression of GSTA3 protein
|
CTD |
PMID:9794803 |
|
NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654
|
|
| G
|
Gsta4
|
glutathione S-transferase alpha 4
|
increases expression
|
ISO
|
coumarin results in increased expression of GSTA4 protein
|
CTD |
PMID:11309284 |
|
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488
|
|
| G
|
Gsta5
|
glutathione S-transferase alpha 5
|
increases expression
|
EXP ISO
|
coumarin results in increased expression of GSTA5 protein coumarin results in increased expression of GSTA1 protein
|
CTD |
PMID:9794803 PMID:11309284 |
|
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
|
|
| G
|
Gstm1
|
glutathione S-transferase mu 1
|
increases expression
|
ISO
|
coumarin results in increased expression of GSTM5 protein
|
CTD |
PMID:11309284 |
|
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
|
|
| G
|
Gstm5
|
glutathione S-transferase, mu 5
|
increases expression decreases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of GSTM3 protein coumarin results in decreased phosphorylation of GSTM3 protein
|
CTD |
PMID:9794803 PMID:35688186 |
|
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
increases expression
|
ISO EXP
|
coumarin results in increased expression of GSTP1 protein
|
CTD |
PMID:9794803 PMID:11309284 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Gstt1
|
glutathione S-transferase theta 1
|
increases expression
|
EXP
|
coumarin results in increased expression of GSTT1 mRNA; coumarin results in increased expression of GSTT1 protein
|
CTD |
PMID:9794803 PMID:9855024 PMID:10413528 |
|
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
|
|
| G
|
Gtf2f1
|
general transcription factor IIF subunit 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GTF2F1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,931,033...1,940,197
Ensembl chr 9:1,930,055...1,940,197
|
|
| G
|
Gtf2h1
|
general transcription factor IIH subunit 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GTF2H1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727
|
|
| G
|
Gtf2i
|
general transcription factor II I
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GTF2I protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677
|
|
| G
|
Gtf3c1
|
general transcription factor IIIC subunit 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GTF3C1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:189,634,645...189,700,848
Ensembl chr 1:189,634,645...189,700,995
|
|
| G
|
Gtf3c2
|
general transcription factor IIIC subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GTF3C2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:30,913,263...30,941,305
Ensembl chr 6:30,923,106...30,940,465
|
|
| G
|
Gtf3c4
|
general transcription factor IIIC subunit 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of GTF3C4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:32,552,773...32,570,705
Ensembl chr 3:32,555,628...32,570,689
|
|
| G
|
Gtpbp1
|
GTP binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GTPBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:113,128,645...113,153,094
Ensembl chr 7:113,128,670...113,154,621
|
|
| G
|
Gtse1
|
G-2 and S-phase expressed 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of GTSE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:118,829,903...118,846,661
|
|
| G
|
Gvin1
|
GTPase, very large interferon inducible 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of GVINP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:169,689,178...169,718,522
Ensembl chr 1:169,691,586...169,718,522
|
|
| G
|
H1f5
|
H1.5 linker histone, cluster member
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of H1-5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:47,421,843...47,477,387
|
|
| G
|
Hal
|
histidine ammonia lyase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of HAL mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
|
|
| G
|
Hao2
|
hydroxyacid oxidase 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of HAO2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
|
|
| G
|
Hapstr2
|
HUWE1 associated protein modifying stress responses 2
|
increases expression
|
EXP
|
coumarin results in increased expression of HAPSTR2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr X:143,958,364...143,960,399
Ensembl chr X:143,958,032...143,960,240
|
|
| G
|
Haspin
|
histone H3 associated protein kinase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HASPIN protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:58,246,244...58,249,031
Ensembl chr10:58,240,447...58,249,249
|
|
| G
|
Haus6
|
HAUS augmin like complex subunit 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HAUS6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:106,162,526...106,201,503
Ensembl chr 5:106,162,526...106,199,072
|
|
| G
|
Hba-a2
|
hemoglobin alpha, adult chain 2
|
multiple interactions
|
EXP
|
coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein]
|
CTD |
PMID:19647726 |
|
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
|
|
| G
|
Hcfc1
|
host cell factor C1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HCFC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:156,839,100...156,864,132
Ensembl chr X:156,839,100...156,863,813
|
|
| G
|
Hdac1
|
histone deacetylase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HDAC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
|
|
| G
|
Hdac2
|
histone deacetylase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HDAC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311
|
|
| G
|
Hdac7
|
histone deacetylase 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HDAC7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:130,803,013...130,841,181
Ensembl chr 7:130,803,013...130,841,017
|
|
| G
|
Hdgfl2
|
HDGF like 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HDGFL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:996,687...1,016,352
Ensembl chr 9:996,758...1,016,735
|
|
| G
|
Heatr6
|
HEAT repeat containing 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HEATR6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:69,132,532...69,161,334
Ensembl chr10:69,132,181...69,162,945
|
|
| G
|
Hectd4
|
HECT domain E3 ubiquitin protein ligase 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HECTD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:40,800,232...40,991,584
Ensembl chr12:40,843,770...40,991,798
|
|
| G
|
Hells
|
helicase, lymphoid specific
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HELLS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228
|
|
| G
|
Helq
|
helicase, POLQ-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HELQ protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:9,122,978...9,167,310
Ensembl chr14:9,122,978...9,167,310
|
|
| G
|
Helz
|
helicase with zinc finger
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HELZ protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:92,979,039...93,144,868
Ensembl chr10:92,999,733...93,138,075
|
|
| G
|
Herc1
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HERC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:75,796,347...75,965,347
Ensembl chr 8:75,796,357...75,965,347
|
|
| G
|
Herc2
|
HECT and RLD domain containing E3 ubiquitin protein ligase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HERC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:116,009,681...116,243,888
Ensembl chr 1:116,040,736...116,243,884
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression
|
ISO
|
coumarin analog results in increased expression of HIF1A mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hipk1
|
homeodomain interacting protein kinase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HIPK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:193,937,261...193,975,164
|
|
| G
|
Hirip3
|
HIRA interacting protein 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HIRIP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:190,903,065...190,905,610
Ensembl chr 1:190,902,593...190,905,607
|
|
| G
|
Hivep1
|
HIVEP zinc finger 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HIVEP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:22,790,855...22,920,359
Ensembl chr17:22,790,855...22,917,196
|
|
| G
|
Hjurp
|
Holliday junction recognition protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HJURP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:96,301,183...96,315,587
Ensembl chr 9:96,302,530...96,315,657
|
|
| G
|
Hlcs
|
holocarboxylase synthetase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HLCS protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082
|
|
| G
|
Hmces
|
5-hydroxymethylcytosine binding, ES cell specific
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HMCES protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:121,950,129...121,972,937
Ensembl chr 4:121,950,840...121,972,891
|
|
| G
|
Hmga1
|
high mobility group AT-hook 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HMGA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,613,471...5,620,593
|
|
| G
|
Hmgcr
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
increases expression
|
EXP
|
coumarin results in increased expression of HMGCR mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
|
|
| G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HMGCS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
|
|
| G
|
Hmgn1
|
high mobility group nucleosome binding domain 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HMGN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771
|
|
| G
|
Hmgxb4
|
HMG-box containing 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HMGXB4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:13,370,559...13,409,306
Ensembl chr19:13,370,376...13,409,306
|
|
| G
|
Hmx3
|
H6 family homeobox 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HMX3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:195,743,411...195,745,375
Ensembl chr 1:195,743,271...195,746,444
|
|
| G
|
Hnrnpa1
|
heterogeneous nuclear ribonucleoprotein A1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HNRNPA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085
|
|
| G
|
Hnrnpa2b1
|
heterogeneous nuclear ribonucleoprotein A2/B1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HNRNPA2B1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572
|
|
| G
|
Hnrnpc
|
heterogeneous nuclear ribonucleoprotein C
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HNRNPC protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:27,253,098...27,282,779
Ensembl chr15:27,253,098...27,282,715
|
|
| G
|
Hnrnpd
|
heterogeneous nuclear ribonucleoprotein D
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HNRNPD protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,919,739...9,938,066
|
|
| G
|
Hnrnpf
|
heterogeneous nuclear ribonucleoprotein F
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HNRNPF protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769
|
|
| G
|
Hnrnph1
|
heterogeneous nuclear ribonucleoprotein H1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HNRNPH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:35,187,412...35,203,909
Ensembl chr10:35,193,890...35,203,906
|
|
| G
|
Hnrnpk
|
heterogeneous nuclear ribonucleoprotein K
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HNRNPK protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565
|
|
| G
|
Hnrnpl
|
heterogeneous nuclear ribonucleoprotein L
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HNRNPL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:93,226,373...93,239,084
Ensembl chr 1:93,235,729...93,239,061
|
|
| G
|
Hnrnpll
|
heterogeneous nuclear ribonucleoprotein L-like
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HNRNPLL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:20,720,013...20,752,803
Ensembl chr 6:20,722,184...20,752,802
|
|
| G
|
Hnrnpm
|
heterogeneous nuclear ribonucleoprotein M
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HNRNPM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:15,140,877...15,178,871
Ensembl chr 7:15,129,287...15,178,871
|
|
| G
|
Hnrnpu
|
heterogeneous nuclear ribonucleoprotein U
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HNRNPU protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:92,609,791...92,618,580
Ensembl chr13:92,605,216...92,618,612
|
|
| G
|
Hnrnpul1
|
heterogeneous nuclear ribonucleoprotein U-like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HNRNPUL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:90,356,182...90,391,923
Ensembl chr 1:90,356,182...90,390,370
|
|
| G
|
Hook3
|
hook microtubule-tethering protein 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HOOK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:72,656,929...72,751,696
Ensembl chr16:72,657,019...72,764,071
|
|
| G
|
Hoxc10
|
homeo box C10
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HOXC10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,982,222...135,987,442
Ensembl chr 7:135,982,065...135,986,712
|
|
| G
|
Hpgds
|
hematopoietic prostaglandin D synthase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HPGDS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501
|
|
| G
|
Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HPRT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
| G
|
Hps5
|
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HPS5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:106,417,902...106,457,220
Ensembl chr 1:106,417,902...106,452,859
|
|
| G
|
Hsd17b1
|
hydroxysteroid (17-beta) dehydrogenase 1
|
multiple interactions
|
ISO
|
coumarin analog inhibits the reaction [[HSD17B1 protein co-treated with NADP] results in increased reduction of Estrone]
|
CTD |
PMID:21232530 |
|
NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,510,011...86,512,210
|
|
| G
|
Hsd3b1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HSD3B1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:188,858,574...188,864,694
|
|
| G
|
Hsdl1
|
hydroxysteroid dehydrogenase like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HSDL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:64,524,435...64,540,527
Ensembl chr19:64,525,891...64,540,762
|
|
| G
|
Hsf1
|
heat shock transcription factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HSF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
|
|
| G
|
Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HSP90AA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
|
|
| G
|
Hsp90ab1
|
heat shock protein 90 alpha family class B member 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HSP90AB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
|
|
| G
|
Hsp90b1
|
heat shock protein 90 beta family member 1
|
increases expression
|
EXP
|
coumarin results in increased expression of HSP90B1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
|
|
| G
|
Hspa1b
|
heat shock protein family A (Hsp70) member 1B
|
increases expression
|
EXP
|
coumarin results in increased expression of HSPA1B mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979
|
|
| G
|
Hspa8
|
heat shock protein family A (Hsp70) member 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of HSPA8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
|
|
| G
|
Htatsf1
|
HIV-1 Tat specific factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HTATSF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:139,972,742...139,986,923
Ensembl chr X:139,972,742...139,986,923
|
|
| G
|
Htt
|
huntingtin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of HTT protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668
|
|
| G
|
Huwe1
|
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of HUWE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:24,350,708...24,480,798
Ensembl chr X:24,353,217...24,480,798
|
|
| G
|
Hyou1
|
hypoxia up-regulated 1
|
increases expression
|
EXP
|
coumarin results in increased expression of HYOU1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997
|
|
| G
|
Ibtk
|
inhibitor of Bruton tyrosine kinase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of IBTK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:95,505,630...95,579,435
Ensembl chr 8:95,505,630...95,578,301
|
|
| G
|
Ice1
|
interactor of little elongation complex ELL subunit 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ICE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:34,468,839...34,508,346
Ensembl chr 1:34,468,659...34,508,346
|
|
| G
|
Ice2
|
interactor of little elongation complex ELL subunit 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ICE2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:78,921,962...78,965,983
Ensembl chr 8:78,924,421...78,966,200
|
|
| G
|
Igf2bp3
|
insulin-like growth factor 2 mRNA binding protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of IGF2BP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730
|
|
| G
|
Igfals
|
insulin-like growth factor binding protein, acid labile subunit
|
decreases expression
|
EXP
|
coumarin results in decreased expression of IGFALS mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
|
|
| G
|
Il1b
|
interleukin 1 beta
|
increases expression decreases expression
|
EXP ISO
|
coumarin results in increased expression of IL1B mRNA coumarin analog results in decreased expression of IL1B protein
|
CTD |
PMID:15135310 PMID:32578917 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1rap
|
interleukin 1 receptor accessory protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of IL1RAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:87,567,813...87,704,346
Ensembl chr11:87,575,116...87,704,342
|
|
| G
|
Il6
|
interleukin 6
|
increases expression decreases expression
|
EXP ISO
|
coumarin results in increased expression of IL6 mRNA coumarin analog results in decreased expression of IL6 mRNA; coumarin analog results in decreased expression of IL6 protein
|
CTD |
PMID:15135310 PMID:32578917 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Ilf3
|
interleukin enhancer binding factor 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ILF3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:28,198,454...28,236,634
Ensembl chr 8:28,198,543...28,236,612
|
|
| G
|
Incenp
|
inner centromere protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of INCENP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:215,945,558...216,017,247
Ensembl chr 1:215,948,283...215,977,084
|
|
| G
|
Inf2
|
inverted formin 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of INF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:137,470,259...137,497,039
Ensembl chr 6:137,470,286...137,497,039
|
|
| G
|
Ing5
|
inhibitor of growth family, member 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ING5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:101,772,845...101,793,734
Ensembl chr 9:101,773,724...101,793,728
|
|
| G
|
Ino80
|
INO80 complex ATPase subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of INO80 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:126,822,280...126,919,532
Ensembl chr 3:126,822,280...126,919,532
|
|
| G
|
Ino80e
|
INO80 complex subunit E
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of INO80E protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:190,891,315...190,902,902
Ensembl chr 1:190,891,936...190,902,541
|
|
| G
|
Ins1
|
insulin 1
|
multiple interactions
|
EXP
|
coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein]; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]
|
CTD |
PMID:19647726 PMID:21630391 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
|
|
| G
|
Ints12
|
integrator complex subunit 12
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of INTS12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:224,265,787...224,283,523
Ensembl chr 2:224,265,736...224,283,516
|
|
| G
|
Ints13
|
integrator complex subunit 13
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of INTS13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:181,190,438...181,222,235
Ensembl chr 4:181,189,765...181,222,235
|
|
| G
|
Ipo5
|
importin 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of IPO5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:104,397,626...104,447,985
Ensembl chr15:104,397,276...104,447,985
|
|
| G
|
Iqgap1
|
IQ motif containing GTPase activating protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of IQGAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:144,088,793...144,179,043
|
|
| G
|
Irf3
|
interferon regulatory factor 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of IRF3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401
|
|
| G
|
Irs1
|
insulin receptor substrate 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of IRS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
|
|
| G
|
Irs2
|
insulin receptor substrate 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of IRS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
|
|
| G
|
Isyna1
|
inositol-3-phosphate synthase 1
|
increases expression
|
EXP
|
coumarin results in increased expression of ISYNA1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955
|
|
| G
|
Itpr3
|
inositol 1,4,5-trisphosphate receptor, type 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ITPR3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,118,834...5,204,184
|
|
| G
|
Itprid2
|
ITPR interacting domain containing 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ITPRID2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:84,943,572...84,980,993
Ensembl chr 3:84,939,808...84,980,899
|
|
| G
|
Itsn2
|
intersectin 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ITSN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:33,336,086...33,446,818
Ensembl chr 6:33,336,441...33,446,818
|
|
| G
|
Ivns1abp
|
influenza virus NS1A binding protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of IVNS1ABP protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:65,977,069...65,996,685
Ensembl chr13:65,977,045...65,997,547
|
|
| G
|
Iws1
|
interacts with SUPT6H, CTD assembly factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of IWS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:23,969,352...24,011,560
Ensembl chr18:23,969,733...24,010,415
|
|
| G
|
Jade2
|
jade family PHD finger 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of JADE2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:36,576,187...36,625,129
Ensembl chr10:36,576,187...36,623,532
|
|
| G
|
Jade3
|
jade family PHD finger 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of JADE3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:4,222,369...4,424,164
Ensembl chr X:4,223,425...4,398,627
|
|
| G
|
Jmjd1c
|
jumonji domain containing 1C
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of JMJD1C protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:21,330,990...21,508,580
Ensembl chr20:21,330,990...21,461,916
|
|
| G
|
Josd2
|
Josephin domain containing 2
|
increases expression
|
EXP
|
coumarin results in increased expression of JOSD2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:104,097,382...104,101,271
Ensembl chr 1:104,097,376...104,101,277
|
|
| G
|
Jph1
|
junctophilin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of JPH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:6,813,553...6,920,488
Ensembl chr 5:6,813,602...6,906,241
|
|
| G
|
Jph3
|
junctophilin 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of JPH3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:66,702,497...66,763,948
Ensembl chr19:66,702,680...66,763,937
|
|
| G
|
Jrkl
|
JRK-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of JRKL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:18,505,808...18,508,704
Ensembl chr 8:18,480,815...18,514,962
|
|
| G
|
Jund
|
JunD proto-oncogene, AP-1 transcription factor subunit
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of JUND protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
|
|
| G
|
Kank1
|
KN motif and ankyrin repeat domains 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KANK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:232,445,658...232,500,839
|
|
| G
|
Kank2
|
KN motif and ankyrin repeat domains 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KANK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:28,587,770...28,617,212
Ensembl chr 8:28,587,770...28,616,993
|
|
| G
|
Kansl3
|
KAT8 regulatory NSL complex subunit 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KANSL3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:46,058,070...46,101,643
Ensembl chr 9:46,058,071...46,101,521
|
|
| G
|
Kat5
|
lysine acetyltransferase 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KAT5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:212,325,090...212,332,587
|
|
| G
|
Kat6a
|
lysine acetyltransferase 6A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KAT6A protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:75,787,411...75,868,584
Ensembl chr16:75,787,411...75,866,099
|
|
| G
|
Kat7
|
lysine acetyltransferase 7
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KAT7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:80,718,335...80,752,387
Ensembl chr10:80,718,335...80,752,387
|
|
| G
|
Kat8
|
lysine acetyltransferase 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KAT8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,954,827...191,967,107
Ensembl chr 1:191,954,438...191,967,105
|
|
| G
|
Katnip
|
katanin interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KATNIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:189,700,838...189,867,402
Ensembl chr 1:189,700,775...189,867,402
|
|
| G
|
Kcnk2
|
potassium two pore domain channel subfamily K member 2
|
increases expression
|
EXP
|
coumarin results in increased expression of KCNK2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:103,297,387...103,494,686
Ensembl chr13:103,297,393...103,494,686
|
|
| G
|
Kctd10
|
potassium channel tetramerization domain containing 10
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KCTD10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:47,890,777...47,909,391
Ensembl chr12:47,890,819...47,909,390
|
|
| G
|
Kctd12
|
potassium channel tetramerization domain containing 12
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KCTD12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:86,214,786...86,220,725
Ensembl chr15:86,214,840...86,224,539
|
|
| G
|
Kctd3
|
potassium channel tetramerization domain containing 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KCTD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:103,041,488...103,080,069
Ensembl chr13:103,041,490...103,080,009
|
|
| G
|
Kdm1a
|
lysine demethylase 1A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KDM1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:154,065,543...154,121,775
|
|
| G
|
Kdm2a
|
lysine demethylase 2A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KDM2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:211,041,859...211,125,749
Ensembl chr 1:211,041,885...211,084,479
|
|
| G
|
Kdm4b
|
lysine demethylase 4B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KDM4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,245,885...1,324,384
Ensembl chr 9:1,245,899...1,324,384
|
|
| G
|
Kdm5c
|
lysine demethylase 5C
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KDM5C protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:24,821,568...24,866,423
Ensembl chr X:24,824,859...24,866,423
|
|
| G
|
Kdr
|
kinase insert domain receptor
|
increases expression
|
ISO
|
coumarin analog results in increased expression of KDR mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
|
|
| G
|
Khdrbs1
|
KH RNA binding domain containing, signal transduction associated 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KHDRBS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:147,337,048...147,374,604
Ensembl chr 5:147,347,904...147,373,448
|
|
| G
|
Khsrp
|
KH-type splicing regulatory protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KHSRP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,949,557...1,959,400
Ensembl chr 9:1,949,557...1,959,497
|
|
| G
|
Kiaa0319l
|
KIAA0319 like
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KIAA0319L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:144,332,242...144,425,182
Ensembl chr 5:144,332,207...144,425,190
|
|
| G
|
Kiaa1671
|
KIAA1671 homolog
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KIAA1671 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:49,069,929...49,212,604
Ensembl chr12:49,069,940...49,212,604
|
|
| G
|
Kidins220
|
kinase D-interacting substrate 220
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KIDINS220 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:47,346,790...47,435,599
Ensembl chr 6:47,346,832...47,431,865
|
|
| G
|
Kif11
|
kinesin family member 11
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KIF11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
|
|
| G
|
Kif13b
|
kinesin family member 13B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KIF13B protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:43,084,059...43,241,719
Ensembl chr15:43,080,910...43,241,719
|
|
| G
|
Kif15
|
kinesin family member 15
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KIF15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202
|
|
| G
|
Kif18b
|
kinesin family member 18B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KIF18B protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:88,370,520...88,392,388
Ensembl chr10:88,370,524...88,389,691
|
|
| G
|
Kif20a
|
kinesin family member 20A
|
decreases expression
|
EXP
|
coumarin results in decreased expression of KIF20A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909
|
|
| G
|
Kif21a
|
kinesin family member 21A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KIF21A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:123,942,079...124,058,594
Ensembl chr 7:123,942,081...124,058,540
|
|
| G
|
Kif22
|
kinesin family member 22
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KIF22 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:191,065,875...191,080,878
|
|
| G
|
Kif24
|
kinesin family member 24
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KIF24 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:61,357,078...61,423,882
Ensembl chr 5:61,357,940...61,399,379
|
|
| G
|
Kif2c
|
kinesin family member 2C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KIF2C protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
|
|
| G
|
Kif4a
|
kinesin family member 4A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KIF4A protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:69,761,803...69,864,335
Ensembl chr X:69,761,883...69,864,335
|
|
| G
|
Klf2
|
KLF transcription factor 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of KLF2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768
|
|
| G
|
Klhdc4
|
kelch domain containing 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KLHDC4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:66,769,558...66,802,626
Ensembl chr19:66,769,558...66,838,346
|
|
| G
|
Klhl6
|
kelch-like family member 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KLHL6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:94,475,262...94,514,653
Ensembl chr11:94,475,262...94,514,623
|
|
| G
|
Kmt2a
|
lysine methyltransferase 2A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KMT2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317
|
|
| G
|
Kmt2d
|
lysine methyltransferase 2D
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KMT2D protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:131,859,696...131,900,072
|
|
| G
|
Knop1
|
lysine-rich nucleolar protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KNOP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:182,611,758...182,630,610
Ensembl chr 1:182,611,758...182,630,901
|
|
| G
|
Knstrn
|
kinetochore-localized astrin/SPAG5 binding protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KNSTRN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:126,254,663...126,274,418
|
|
| G
|
Kpna6
|
karyopherin subunit alpha 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of KPNA6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:147,272,466...147,307,523
Ensembl chr 5:147,275,918...147,305,851
|
|
| G
|
Krt18
|
keratin 18
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of KRT18 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
|
|
| G
|
Krt19
|
keratin 19
|
decreases expression
|
EXP
|
coumarin results in decreased expression of KRT19 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952
|
|
| G
|
Kynu
|
kynureninase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of KYNU mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014
|
|
| G
|
L3mbtl2
|
L3MBTL histone methyl-lysine binding protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of L3MBTL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:115,066,427...115,087,625
Ensembl chr 7:115,066,486...115,087,598
|
|
| G
|
Lad1
|
ladinin 1
|
increases expression
|
EXP
|
coumarin results in increased expression of LAD1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:49,801,347...49,815,709
Ensembl chr13:49,800,472...49,815,709
|
|
| G
|
Lamtor1
|
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LAMTOR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:165,684,091...165,703,178
|
|
| G
|
Larp1
|
La ribonucleoprotein 1, translational regulator
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LARP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:42,691,833...42,746,816
Ensembl chr10:42,691,600...42,746,816
|
|
| G
|
Larp4
|
La ribonucleoprotein 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LARP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:132,983,276...133,031,514
Ensembl chr 7:132,980,385...133,029,633
|
|
| G
|
Larp4b
|
La ribonucleoprotein 4B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LARP4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:65,813,125...65,908,920
Ensembl chr17:65,830,022...65,908,676
|
|
| G
|
Lasp1
|
LIM and SH3 protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LASP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988
|
|
| G
|
Lats1
|
large tumor suppressor kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LATS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:3,980,544...4,014,029
|
|
| G
|
Lats2
|
large tumor suppressor kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LATS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:35,940,632...35,992,225
Ensembl chr15:35,940,632...35,980,842
|
|
| G
|
Lcor
|
ligand dependent nuclear receptor corepressor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LCOR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:250,247,965...250,354,985
Ensembl chr 1:250,247,934...250,354,985
|
|
| G
|
Ldha
|
lactate dehydrogenase A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LDHA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Lemd2
|
LEM domain nuclear envelope protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LEMD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:5,284,275...5,298,281
Ensembl chr20:5,284,275...5,298,328
|
|
| G
|
Leng1
|
leukocyte receptor cluster member 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LENG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:74,467,343...74,472,275
Ensembl chr 1:74,467,326...74,472,280
|
|
| G
|
Leo1
|
LEO1 homolog, Paf1/RNA polymerase II complex component
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LEO1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:85,080,036...85,104,471
Ensembl chr 8:85,079,996...85,105,094
|
|
| G
|
Lgalsl
|
galectin-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LGALSL protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487
|
|
| G
|
Lig1
|
DNA ligase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LIG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
|
|
| G
|
Lig3
|
DNA ligase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LIG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:68,215,371...68,238,705
Ensembl chr10:68,215,407...68,238,704
|
|
| G
|
Lima1
|
LIM domain and actin binding 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LIMA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:132,780,556...132,880,386
|
|
| G
|
Limch1
|
LIM and calponin homology domains 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LIMCH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,466,433...41,778,837
|
|
| G
|
Limd1
|
LIM domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LIMD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:131,998,262...132,045,924
Ensembl chr 8:131,999,770...132,045,922
|
|
| G
|
Lin37
|
lin-37 DREAM MuvB core complex component
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LIN37 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:94,936,512...94,940,444
Ensembl chr 1:94,936,512...94,940,444
|
|
| G
|
Lin9
|
lin-9 DREAM MuvB core complex component
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LIN9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:94,906,185...94,951,541
Ensembl chr13:94,906,548...94,951,539
|
|
| G
|
Llgl2
|
LLGL scribble cell polarity complex component 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LLGL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,549,911...101,585,466
Ensembl chr10:101,549,862...101,585,464
|
|
| G
|
Lmf2
|
lipase maturation factor 2
|
increases expression
|
EXP
|
coumarin results in increased expression of LMF2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:122,297,971...122,302,423
Ensembl chr 7:122,297,973...122,302,423
|
|
| G
|
Lmna
|
lamin A/C
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LMNA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072
|
|
| G
|
Lmnb2
|
lamin B2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LMNB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:9,440,128...9,459,342
|
|
| G
|
Lmo7
|
LIM domain 7
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LMO7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:84,981,689...85,184,554
Ensembl chr15:84,981,735...85,184,551
|
|
| G
|
Lpin2
|
lipin 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LPIN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:118,529,988...118,604,796
Ensembl chr 9:118,529,943...118,604,796
|
|
| G
|
Lpin3
|
lipin 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LPIN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:169,960,522...169,978,031
|
|
| G
|
Lpo
|
lactoperoxidase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LPO protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:73,104,170...73,124,683
Ensembl chr10:73,104,188...73,123,456
|
|
| G
|
Lrba
|
LPS responsive beige-like anchor protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LRBA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:173,919,330...174,500,536
Ensembl chr 2:173,921,747...174,500,527
|
|
| G
|
Lrch1
|
leucine rich repeats and calponin homology domain containing 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LRCH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:56,469,403...56,659,201
Ensembl chr15:56,481,395...56,659,100
|
|
| G
|
Lrch4
|
leucine rich repeats and calponin homology domain containing 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LRCH4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:24,694,364...24,709,354
Ensembl chr12:24,694,370...24,706,412
|
|
| G
|
Lrp3
|
LDL receptor related protein 3
|
affects expression
|
EXP
|
coumarin affects the expression of LRP3 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057
|
|
| G
|
Lrrc39
|
leucine rich repeat containing 39
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LRRC39 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:207,201,039...207,220,375
Ensembl chr 2:207,201,042...207,220,371
|
|
| G
|
Lrrc47
|
leucine rich repeat containing 47
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LRRC47 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:169,852,926...169,862,598
Ensembl chr 5:169,852,897...169,862,598
|
|
| G
|
Lrrfip1
|
LRR binding FLII interacting protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LRRFIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:99,039,590...99,167,805
Ensembl chr 9:99,039,614...99,167,779
|
|
| G
|
Lrwd1
|
leucine-rich repeats and WD repeat domain containing 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LRWD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:26,166,648...26,179,689
Ensembl chr12:26,166,648...26,185,200
|
|
| G
|
Lsm11
|
LSM11, U7 small nuclear RNA associated
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LSM11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:30,869,168...30,887,275
Ensembl chr10:30,872,054...30,887,269
|
|
| G
|
Lsm14a
|
LSM14A mRNA processing body assembly factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LSM14A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:96,101,990...96,146,578
Ensembl chr 1:96,101,992...96,146,448
|
|
| G
|
Lsm14b
|
LSM family member 14B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LSM14B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:187,503,251...187,514,041
Ensembl chr 3:187,503,045...187,512,473
|
|
| G
|
Ltv1
|
LTV1 ribosome biogenesis factor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LTV1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:9,385,834...9,398,557
Ensembl chr 1:9,385,830...9,398,677
|
|
| G
|
Luc7l1
|
LUC7 pre-mRNA splicing factor like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LUC7L protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:15,777,837...15,811,586
Ensembl chr10:15,777,829...15,817,940
|
|
| G
|
Luc7l2
|
LUC7 pre-mRNA splicing factor like 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LUC7L2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:68,251,435...68,314,861
Ensembl chr 4:68,271,414...68,314,837
|
|
| G
|
Luc7l3
|
LUC7 pre-mRNA splicing factor like 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of LUC7L3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:79,737,457...79,773,478
Ensembl chr10:79,736,853...79,773,429
|
|
| G
|
Luzp1
|
leucine zipper protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of LUZP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:153,989,570...154,065,071
Ensembl chr 5:153,987,683...154,070,438
|
|
| G
|
Lyar
|
Ly1 antibody reactive
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LYAR protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:76,789,193...76,802,973
Ensembl chr14:76,789,200...76,802,765
|
|
| G
|
Lysmd2
|
LysM domain containing 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LYSMD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:85,259,443...85,274,876
Ensembl chr 8:85,259,410...85,275,241
|
|
| G
|
Lzts2
|
leucine zipper tumor suppressor 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of LZTS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:253,824,073...253,837,614
Ensembl chr 1:253,829,119...253,837,632
|
|
| G
|
M6pr
|
mannose-6-phosphate receptor, cation dependent
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of M6PR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:157,173,154...157,182,293
Ensembl chr 4:157,173,125...157,182,277
|
|
| G
|
Macf1
|
microtubule-actin crosslinking factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MACF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890
|
|
| G
|
Macir
|
macrophage immunometabolism regulator
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MACIR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:105,868,072...105,888,128
Ensembl chr 9:105,866,641...105,889,758
|
|
| G
|
Madd
|
MAP-kinase activating death domain
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MADD protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:97,570,787...97,613,509
|
|
| G
|
Mael
|
maelstrom spermatogenic transposon silencer
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MAEL protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:80,990,040...81,029,623
Ensembl chr13:80,990,040...81,029,623
|
|
| G
|
Maf1
|
MAF1 homolog, negative regulator of RNA polymerase III
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:109,955,876...109,958,909
Ensembl chr 7:109,955,282...109,958,910
|
|
| G
|
Mafk
|
MAF bZIP transcription factor K
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MAFK protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192
|
|
| G
|
Mageb6
|
MAGE family member B6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MAGEB6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:60,468,437...60,469,905
Ensembl chr X:60,468,437...60,469,905
|
|
| G
|
Map1b
|
microtubule-associated protein 1B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MAP1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094
|
|
| G
|
Map1s
|
microtubule-associated protein 1S
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MAP1S protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:18,551,573...18,561,760
Ensembl chr16:18,551,573...18,562,141
|
|
| G
|
Map3k2
|
mitogen activated protein kinase kinase kinase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MAP3K2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323
|
|
| G
|
Map3k7
|
mitogen activated protein kinase kinase kinase 7
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MAP3K7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012
|
|
| G
|
Map4
|
microtubule-associated protein 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MAP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:118,800,393...118,942,805
Ensembl chr 8:118,804,022...118,942,805
|
|
| G
|
Map4k4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MAP4K4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353
|
|
| G
|
Map7d1
|
MAP7 domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MAP7D1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:143,812,467...143,837,597
Ensembl chr 5:143,811,924...143,837,021
|
|
| G
|
Mapk6
|
mitogen-activated protein kinase 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MAPK6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:85,027,141...85,050,236
Ensembl chr 8:85,027,144...85,050,236
|
|
| G
|
Mapre1
|
microtubule-associated protein, RP/EB family, member 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MAPRE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:162,679,020...162,707,167
Ensembl chr 3:162,673,195...162,711,210
|
|
| G
|
Mapt
|
microtubule-associated protein tau
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MAPT protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
|
|
| G
|
Marcks
|
myristoylated alanine rich protein kinase C substrate
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MARCKS protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
|
|
| G
|
Marcksl1
|
MARCKS-like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MARCKSL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417
|
|
| G
|
Mark2
|
microtubule affinity regulating kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MARK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,890,213...213,955,417
Ensembl chr 1:213,890,213...213,955,149
|
|
| G
|
Mark3
|
microtubule affinity regulating kinase 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MARK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:136,447,327...136,537,409
Ensembl chr 6:136,448,531...136,537,404
|
|
| G
|
Mast2
|
microtubule associated serine/threonine kinase 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MAST2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:135,013,006...135,152,195
Ensembl chr 5:135,012,058...135,152,161
|
|
| G
|
Mast3
|
microtubule associated serine/threonine kinase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MAST3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:18,670,742...18,699,252
Ensembl chr16:18,670,765...18,697,832
|
|
| G
|
Mastl
|
microtubule associated serine/threonine kinase-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MASTL protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:90,158,592...90,195,550
Ensembl chr17:90,160,068...90,195,564
|
|
| G
|
Mat1a
|
methionine adenosyltransferase 1A
|
affects expression
|
EXP
|
coumarin affects the expression of MAT1A mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr16:17,017,168...17,035,368
Ensembl chr16:17,016,030...17,035,367
|
|
| G
|
Matr3
|
matrin 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MATR3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:27,428,190...27,474,421
Ensembl chr18:27,432,179...27,470,421
|
|
| G
|
Mavs
|
mitochondrial antiviral signaling protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MAVS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:138,904,771...138,919,126
|
|
| G
|
Mbd1
|
methyl-CpG binding domain protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MBD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:70,145,093...70,159,744
Ensembl chr18:70,145,114...70,159,703
|
|
| G
|
Mbd2
|
methyl-CpG binding domain protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MBD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:66,449,196...66,516,112
Ensembl chr18:66,449,358...66,516,111
|
|
| G
|
Mbd4
|
methyl-CpG binding domain 4 DNA glycosylase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MBD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:150,565,655...150,577,578
|
|
| G
|
Mbip
|
MAP3K12 binding inhibitory protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MBIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:79,543,223...79,560,476
Ensembl chr 6:79,543,223...79,560,474
|
|
| G
|
Mbl2
|
mannose binding lectin 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of MBL2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546
|
|
| G
|
Mbtps1
|
membrane-bound transcription factor peptidase, site 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MBTPS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:64,470,245...64,521,438
Ensembl chr19:64,470,545...64,521,342
|
|
| G
|
Mcl1
|
MCL1 apoptosis regulator, BCL2 family member
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MCL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
|
|
| G
|
Mcm10
|
minichromosome maintenance 10 replication initiation factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MCM10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:78,172,049...78,197,644
Ensembl chr17:78,175,398...78,197,636
|
|
| G
|
Mcm2
|
minichromosome maintenance complex component 2
|
increases expression affects phosphorylation
|
EXP ISO
|
coumarin results in increased expression of MCM2 mRNA coumarin affects the phosphorylation of MCM2 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
|
|
| G
|
Mcm3
|
minichromosome maintenance complex component 3
|
increases expression
|
EXP
|
coumarin results in increased expression of MCM3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746
|
|
| G
|
Mcm3ap
|
minichromosome maintenance complex component 3 associated protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MCM3AP protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:12,127,060...12,164,651
Ensembl chr20:12,127,060...12,164,651
|
|
| G
|
Mcm4
|
minichromosome maintenance complex component 4
|
increases expression decreases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of MCM4 mRNA coumarin results in decreased phosphorylation of MCM4 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536
|
|
| G
|
Mcm5
|
minichromosome maintenance complex component 5
|
increases expression increases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of MCM5 mRNA coumarin results in increased phosphorylation of MCM5 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
|
|
| G
|
Mcm6
|
minichromosome maintenance complex component 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MCM6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
|
|
| G
|
Mcm7
|
minichromosome maintenance complex component 7
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MCM7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771
|
|
| G
|
Mcm8
|
minichromosome maintenance 8 homologous recombination repair factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MCM8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:140,539,590...140,569,891
Ensembl chr 3:140,539,647...140,569,891
|
|
| G
|
Mcrip2
|
MAPK regulated co-repressor interacting protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MCRIP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:15,388,325...15,393,302
Ensembl chr10:15,388,325...15,398,730
|
|
| G
|
Mctp1
|
multiple C2 and transmembrane domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MCTP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:7,803,382...8,493,596
|
|
| G
|
Mdc1
|
mediator of DNA damage checkpoint 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960
|
|
| G
|
Mdfic
|
MyoD family inhibitor domain containing
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MDFIC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:44,938,301...45,018,157
Ensembl chr 4:44,938,480...45,018,156
|
|
| G
|
Mdm2
|
MDM2 proto-oncogene
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of MDM2 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
|
|
| G
|
Mdn1
|
midasin AAA ATPase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MDN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:51,851,785...51,982,688
Ensembl chr 5:51,851,809...51,982,688
|
|
| G
|
Mecp2
|
methyl CpG binding protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MECP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:156,932,481...156,995,981
Ensembl chr X:156,941,234...156,943,560
|
|
| G
|
Med1
|
mediator complex subunit 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MED1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545
|
|
| G
|
Med13
|
mediator complex subunit 13
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MED13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:71,584,354...71,674,614
Ensembl chr10:71,584,354...71,673,901
|
|
| G
|
Med13l
|
mediator complex subunit 13L
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MED13L protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:43,468,556...43,665,819
Ensembl chr12:43,468,556...43,665,819
|
|
| G
|
Med19
|
mediator complex subunit 19
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MED19 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:90,168,829...90,179,351
Ensembl chr 3:90,168,829...90,179,351
|
|
| G
|
Med26
|
mediator complex subunit 26
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MED26 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:17,333,770...17,384,797
Ensembl chr16:17,327,734...17,383,603
|
|
| G
|
Mef2d
|
myocyte enhancer factor 2D
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MEF2D protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:175,904,332...175,933,451
Ensembl chr 2:175,903,959...175,930,760
|
|
| G
|
Mepce
|
methylphosphate capping enzyme
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MEPCE protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:24,548,596...24,553,315
Ensembl chr12:24,548,596...24,553,877
|
|
| G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MET protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
|
|
| G
|
Metap2
|
methionyl aminopeptidase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of METAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:30,299,433...30,327,477
Ensembl chr 7:30,299,433...30,327,521
|
|
| G
|
Mettl13
|
methyltransferase 13, eEF1A N-terminus and K55
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of METTL13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:77,419,393...77,433,228
Ensembl chr13:77,419,397...77,433,104
|
|
| G
|
Mettl3
|
methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of METTL3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:27,476,659...27,491,134
Ensembl chr15:27,476,660...27,487,487
|
|
| G
|
Mff
|
mitochondrial fission factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MFF protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:91,455,931...91,484,171
Ensembl chr 9:91,455,871...91,484,171
|
|
| G
|
Mga
|
MAX dimerization protein MGA
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MGA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:127,300,558...127,396,694
Ensembl chr 3:127,328,264...127,394,826
|
|
| G
|
Mgat4b
|
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MGAT4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309
|
|
| G
|
Mgp
|
matrix Gla protein
|
decreases expression
|
ISO
|
coumarin results in decreased expression of MGP mRNA
|
CTD |
PMID:19350115 |
|
NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859
|
|
| G
|
Mgst2
|
microsomal glutathione S-transferase 2
|
increases expression
|
EXP
|
coumarin results in increased expression of MGST2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661
|
|
| G
|
Mgst3
|
microsomal glutathione S-transferase 3
|
decreases expression
|
EXP
|
coumarin results in decreased expression of MGST3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575
|
|
| G
|
Mia2
|
MIA SH3 domain ER export factor 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MIA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:82,522,398...82,620,136
Ensembl chr 6:82,522,422...82,620,178
|
|
| G
|
Mical3
|
microtubule associated monooxygenase, calponin and LIM domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MICAL3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:155,824,941...156,025,003
Ensembl chr 4:155,824,946...156,005,238
|
|
| G
|
Micall1
|
MICAL-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MICALL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:112,557,192...112,587,618
Ensembl chr 7:112,557,192...112,587,618
|
|
| G
|
Mideas
|
mitotic deacetylase associated SANT domain protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MIDEAS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:109,519,011...109,585,631
Ensembl chr 6:109,519,011...109,560,312
|
|
| G
|
Mier3
|
MIER family member 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MIER3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:45,021,167...45,049,745
Ensembl chr 2:45,021,283...45,049,745
|
|
| G
|
Mink1
|
misshapen-like kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MINK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:55,776,879...55,829,406
Ensembl chr10:55,776,993...55,829,406
|
|
| G
|
Mis18bp1
|
MIS18 binding protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MIS18BP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:88,918,743...88,968,225
Ensembl chr 6:88,918,745...88,967,629
|
|
| G
|
Misp
|
mitotic spindle positioning
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MISP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:10,526,980...10,537,159
Ensembl chr 7:10,503,209...10,537,159
|
|
| G
|
Mitf
|
melanocyte inducing transcription factor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MITF protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MKI67 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mllt1
|
MLLT1, super elongation complex subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MLLT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,818,204...1,863,091
Ensembl chr 9:1,818,204...1,863,089
|
|
| G
|
Mllt6
|
MLLT6, PHD finger containing
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MLLT6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:83,152,317...83,175,264
Ensembl chr10:83,153,698...83,175,250
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of MMP2 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
decreases expression multiple interactions
|
ISO
|
coumarin analog results in decreased expression of MMP9 mRNA coumarin analog results in decreased expression of and results in decreased activity of MMP9 protein
|
CTD |
PMID:32578917 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mms22l
|
MMS22-like, DNA repair protein
|
increases expression
|
EXP
|
coumarin results in increased expression of MMS22L mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:42,994,382...43,110,371
Ensembl chr 5:42,994,359...43,110,369
|
|
| G
|
Mnat1
|
MNAT1 component of CDK activating kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MNAT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:97,550,566...97,706,598
Ensembl chr 6:97,550,543...97,706,595
|
|
| G
|
Mon1b
|
MON1 homolog B, secretory trafficking associated
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MON1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:58,526,503...58,534,478
Ensembl chr19:58,526,326...58,533,950
|
|
| G
|
Morc2
|
MORC family CW-type zinc finger 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MORC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:82,752,444...82,794,980
Ensembl chr14:82,752,018...82,794,979
|
|
| G
|
Mpdz
|
multiple PDZ domain crumbs cell polarity complex component
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MPDZ protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:100,812,121...100,966,566
Ensembl chr 5:100,812,124...100,966,504
|
|
| G
|
Mphosph8
|
M-phase phosphoprotein 8
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MPHOSPH8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:34,916,169...34,944,038
Ensembl chr15:34,816,701...34,944,433
|
|
| G
|
Mprip
|
myosin phosphatase Rho interacting protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MPRIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:44,953,472...45,073,388
Ensembl chr10:44,953,500...45,073,388
|
|
| G
|
Mrc2
|
mannose receptor, C type 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MRC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055
|
|
| G
|
Mre11
|
MRE11 homolog, double strand break repair nuclease
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MRE11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904
|
|
| G
|
Mrps24
|
mitochondrial ribosomal protein S24
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MRPS24 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:84,798,649...84,802,777
|
|
| G
|
Mrtfa
|
myocardin related transcription factor A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MRTFA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:114,424,481...114,594,594
Ensembl chr 7:114,424,481...114,594,594
|
|
| G
|
Mrtfb
|
myocardin related transcription factor B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MRTFB protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:1,623,887...1,789,658
Ensembl chr10:1,623,940...1,789,658
|
|
| G
|
Msantd2
|
Myb/SANT DNA binding domain containing 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MSANTD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:45,389,615...45,423,452
Ensembl chr 8:45,389,514...45,423,452
|
|
| G
|
Msantd3
|
Myb/SANT DNA binding domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MSANTD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:67,661,551...67,687,971
Ensembl chr 5:67,661,912...67,684,384
|
|
| G
|
Msantd4
|
Myb/SANT DNA binding domain containing 4 with coiled-coils
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MSANTD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:9,801,921...9,812,529
Ensembl chr 8:9,801,903...9,812,529
|
|
| G
|
Msh6
|
mutS homolog 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MSH6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
|
|
| G
|
Msmo1
|
methylsterol monooxygenase 1
|
affects expression
|
EXP
|
coumarin affects the expression of MSMO1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
|
|
| G
|
Mt1a
|
metallothionein 1A
|
increases expression
|
EXP
|
coumarin results in increased expression of MT1A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
|
|
| G
|
Mt2
|
metallothionein 2
|
increases expression
|
EXP
|
coumarin results in increased expression of MT2A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
|
|
| G
|
Mta1
|
metastasis associated 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MTA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696
|
|
| G
|
Mta2
|
metastasis associated 1 family, member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MTA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:215,267,286...215,276,008
Ensembl chr 1:215,267,046...215,276,062
|
|
| G
|
Mta3
|
metastasis associated 1 family, member 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MTA3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:16,619,575...16,739,732
Ensembl chr 6:16,621,998...16,739,485
|
|
| G
|
Mtcl1
|
microtubule crosslinking factor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MTCL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:113,722,138...113,888,413
Ensembl chr 9:113,753,000...113,888,098
|
|
| G
|
Mtdh
|
metadherin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MTDH protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:67,192,592...67,250,819
Ensembl chr 7:67,192,393...67,249,584
|
|
| G
|
Mthfd2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MTHFD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
|
|
| G
|
Mtmr10
|
myotubularin related protein 10
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MTMR10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:127,271,139...127,322,621
Ensembl chr 1:127,270,870...127,322,621
|
|
| G
|
Mtmr2
|
myotubularin related protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MTMR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:18,899,303...18,949,767
Ensembl chr 8:18,928,126...18,949,766
|
|
| G
|
Mtmr9
|
myotubularin related protein 9
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MTMR9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:41,945,102...41,967,136
Ensembl chr15:41,945,105...41,967,136
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MTOR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Mtss2
|
MTSS I-BAR domain containing 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MTSS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:55,602,180...55,623,955
Ensembl chr19:55,602,498...55,623,950
|
|
| G
|
Mus81
|
MUS81 structure-specific endonuclease subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MUS81 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,219,793...212,225,214
Ensembl chr 1:212,219,795...212,225,068
|
|
| G
|
Mxra7
|
matrix remodeling associated 7
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MXRA7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:102,501,848...102,530,231
Ensembl chr10:102,489,604...102,530,231
|
|
| G
|
Mybbp1a
|
MYB binding protein 1a
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYBBP1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,555,452...57,566,041
|
|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MYBL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Mybl2
|
MYB proto-oncogene like 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYBL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Mycbp2
|
MYC binding protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MYCBP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
|
|
| G
|
Mycn
|
MYCN proto-oncogene, bHLH transcription factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYCN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508
|
|
| G
|
Myh10
|
myosin heavy chain 10
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MYH10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036
|
|
| G
|
Myh9
|
myosin, heavy chain 9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYH9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963
|
|
| G
|
Myo16
|
myosin XVI
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYO16 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:85,586,428...86,066,537
Ensembl chr16:85,586,429...85,973,879
|
|
| G
|
Myo18a
|
myosin XVIIIa
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MYO18A protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,152,303...63,253,543
Ensembl chr10:63,152,103...63,253,543
|
|
| G
|
Myo1e
|
myosin IE
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MYO1E protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:79,768,828...79,961,048
Ensembl chr 8:79,753,596...79,961,045
|
|
| G
|
Myo5a
|
myosin VA
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of MYO5A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265
|
|
| G
|
Myo9b
|
myosin IXb
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of MYO9B protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:17,979,374...18,064,100
Ensembl chr16:17,979,439...18,064,332
|
|
| G
|
Mypn
|
myopalladin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MYPN protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:25,435,554...25,521,149
Ensembl chr20:25,435,554...25,521,149
|
|
| G
|
Myzap
|
myocardial zonula adherens protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of MYZAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:81,036,599...81,123,933
Ensembl chr 8:81,036,601...81,123,810
|
|
| G
|
N4bp1
|
Nedd4 binding protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of N4BP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:36,396,082...36,446,835
Ensembl chr19:36,396,324...36,446,835
|
|
| G
|
Naa10
|
N(alpha)-acetyltransferase 10, NatA catalytic subunit
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NAA10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:156,807,378...156,812,632
Ensembl chr X:156,807,378...156,812,574
|
|
| G
|
Naa30
|
N(alpha)-acetyltransferase 30, NatC catalytic subunit
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NAA30 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:24,935,060...24,954,435
Ensembl chr15:24,935,260...24,954,437
|
|
| G
|
Nab1
|
Ngfi-A binding protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NAB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:56,545,547...56,585,045
Ensembl chr 9:56,545,729...56,614,210
|
|
| G
|
Nab2
|
Ngfi-A binding protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NAB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:65,382,863...65,389,527
Ensembl chr 7:65,382,863...65,389,255
|
|
| G
|
Naf1
|
nuclear assembly factor 1 ribonucleoprotein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:27,604,228...27,634,963
Ensembl chr16:27,603,918...27,634,963
|
|
| G
|
Nagk
|
N-acetylglucosamine kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NAGK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:117,838,761...117,846,304
Ensembl chr 4:117,838,826...117,847,836
|
|
| G
|
Nap1l1
|
nucleosome assembly protein 1-like 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NAP1L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
|
|
| G
|
Nasp
|
nuclear autoantigenic sperm protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NASP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:135,294,599...135,319,992
Ensembl chr 5:135,294,032...135,319,591
|
|
| G
|
Nat8
|
N-acetyltransferase 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NAT8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159
|
|
| G
|
Nav2
|
neuron navigator 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NAV2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:107,799,968...108,458,546
Ensembl chr 1:107,805,096...108,458,546
|
|
| G
|
Ncapd2
|
non-SMC condensin I complex, subunit D2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NCAPD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,655,051...159,677,938
Ensembl chr 4:159,655,051...159,677,938
|
|
| G
|
Ncapd3
|
non-SMC condensin II complex, subunit D3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCAPD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:33,696,214...33,765,520
Ensembl chr 8:33,696,270...33,765,518
|
|
| G
|
Ncapg
|
non-SMC condensin I complex, subunit G
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCAPG protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445
|
|
| G
|
Ncaph
|
non-SMC condensin I complex, subunit H
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCAPH protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502
|
|
| G
|
Ncaph2
|
non-SMC condensin II complex, subunit H2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NCAPH2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:122,302,550...122,319,570
Ensembl chr 7:122,300,252...122,319,569
|
|
| G
|
Ncbp3
|
nuclear cap binding subunit 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NCBP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:58,164,241...58,193,952
Ensembl chr10:58,164,234...58,193,964
|
|
| G
|
Ncl
|
nucleolin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:94,446,682...94,456,083
|
|
| G
|
Ncoa2
|
nuclear receptor coactivator 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCOA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:10,618,722...10,852,776
|
|
| G
|
Ncoa3
|
nuclear receptor coactivator 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCOA3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631
|
|
| G
|
Ncoa5
|
nuclear receptor coactivator 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NCOA5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:174,155,731...174,188,862
Ensembl chr 3:174,155,741...174,188,862
|
|
| G
|
Ncoa7
|
nuclear receptor coactivator 7
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NCOA7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:28,675,426...28,835,886
|
|
| G
|
Ncor1
|
nuclear receptor co-repressor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NCOR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:47,498,852...47,641,612
Ensembl chr10:47,498,852...47,640,350
|
|
| G
|
Ncor2
|
nuclear receptor co-repressor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NCOR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612
|
|
| G
|
Ndc1
|
NDC1 transmembrane nucleoporin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:127,384,172...127,431,093
Ensembl chr 5:127,384,665...127,431,090
|
|
| G
|
Ndel1
|
nudE neurodevelopment protein 1-like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NDEL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:54,001,435...54,080,909
Ensembl chr10:54,016,149...54,062,375
|
|
| G
|
Ndrg1
|
N-myc downstream regulated 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NDRG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913
|
|
| G
|
Ndrg3
|
NDRG family member 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NDRG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:166,007,556...166,070,981
Ensembl chr 3:165,890,091...166,049,887
|
|
| G
|
Ndufv3
|
NADH:ubiquinone oxidoreductase subunit V3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NDUFV3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847 Ensembl chr20:48,468,224...48,488,847
|
|
| G
|
Nectin2
|
nectin cell adhesion molecule 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of NECTIN2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:88,500,087...88,535,305
|
|
| G
|
Nedd4
|
NEDD4 E3 ubiquitin protein ligase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NEDD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:82,264,649...82,349,633
|
|
| G
|
Nedd4l
|
NEDD4 like E3 ubiquitin protein ligase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NEDD4L protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824
|
|
| G
|
Nek9
|
NIMA-related kinase 9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NEK9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:110,675,107...110,715,586
Ensembl chr 6:110,675,107...110,715,586
|
|
| G
|
Nelfa
|
negative elongation factor complex member A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NELFA protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:81,033,470...81,057,546
Ensembl chr14:81,033,514...81,058,719
|
|
| G
|
Nelfb
|
negative elongation factor complex member B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NELFB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:28,409,045...28,425,564
Ensembl chr 3:28,409,050...28,425,564
|
|
| G
|
Nelfe
|
negative elongation factor complex member E
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NELFE protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:3,981,259...3,987,016
Ensembl chr20:3,981,261...3,986,922
|
|
| G
|
Nes
|
nestin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NES protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
|
|
| G
|
Neurl4
|
neuralized E3 ubiquitin protein ligase 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NEURL4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:55,123,471...55,135,971
Ensembl chr10:55,124,324...55,136,223
|
|
| G
|
Nexn
|
nexilin (F actin binding protein)
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NEXN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:243,846,736...243,878,268
Ensembl chr 2:243,846,433...243,887,114
|
|
| G
|
Nf1
|
neurofibromin 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,804,266...65,034,946
|
|
| G
|
Nf2
|
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151
|
|
| G
|
Nfat5
|
nuclear factor of activated T-cells 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NFAT5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418
|
|
| G
|
Nfatc2ip
|
nuclear factor of activated T-cells 2 interacting protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NFATC2IP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:190,385,416...190,403,309
Ensembl chr 1:190,387,437...190,402,413
|
|
| G
|
Nfatc3
|
nuclear factor of activated T-cells 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NFATC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
affects activity increases activity
|
ISO
|
coumarin affects the activity of NFE2L2 protein coumarin results in increased activity of NFE2L2 protein
|
CTD |
PMID:11309284 PMID:30114225 PMID:30203046 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nfia
|
nuclear factor I/A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NFIA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395
|
|
| G
|
Nfib
|
nuclear factor I/B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NFIB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945
|
|
| G
|
Nfic
|
nuclear factor I/C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NFIC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:8,928,423...8,963,455
Ensembl chr 7:8,904,117...8,963,409
|
|
| G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NFKB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Nfrkb
|
nuclear factor related to kappa B binding protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NFRKB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:38,089,574...38,121,506
Ensembl chr 8:38,089,999...38,121,501
|
|
| G
|
Nfx1
|
nuclear transcription factor, X-box binding 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NFX1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889
|
|
| G
|
Nfxl1
|
nuclear transcription factor, X-box binding-like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NFXL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:35,980,058...36,021,478
Ensembl chr14:35,980,057...36,023,281
|
|
| G
|
Ngdn
|
neuroguidin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NGDN protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:32,459,898...32,467,260
Ensembl chr15:32,399,109...32,467,260
|
|
| G
|
Nherf1
|
NHERF family PDZ scaffold protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NHERF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579
|
|
| G
|
Nherf2
|
NHERF family PDZ scaffold protein 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NHERF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:14,167,005...14,177,519
Ensembl chr10:14,167,005...14,177,593
|
|
| G
|
Nhsl3
|
NHS like 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NHSL3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:146,848,747...146,877,504
Ensembl chr 5:146,848,747...146,877,504
|
|
| G
|
Niban1
|
niban apoptosis regulator 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NIBAN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
|
|
| G
|
Nifk
|
nucleolar protein interacting with the FHA domain of MKI67
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NIFK protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561
|
|
| G
|
Nipbl
|
NIPBL, cohesin loading factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NIPBL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:59,126,676...59,314,841
Ensembl chr 2:59,126,676...59,293,277
|
|
| G
|
Nkap
|
NFKB activating protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NKAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:121,238,714...121,258,360
Ensembl chr X:121,238,404...121,261,238
|
|
| G
|
Nkrf
|
NFKB repressing factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NKRF protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:120,992,038...121,010,251
Ensembl chr X:120,992,038...121,010,251
|
|
| G
|
Nktr
|
natural killer cell triggering receptor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NKTR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:130,255,541...130,298,001
Ensembl chr 8:130,259,461...130,298,008
|
|
| G
|
Nob1
|
NIN1 (RPN12) binding protein 1 homolog
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NOB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:52,232,543...52,245,824
Ensembl chr19:52,232,543...52,256,189
|
|
| G
|
Noc2l
|
NOC2-like nucleolar associated transcriptional repressor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NOC2L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:172,102,369...172,114,168
Ensembl chr 5:172,101,223...172,114,162
|
|
| G
|
Noc3l
|
NOC3-like DNA replication regulator
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOC3L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:245,969,179...245,997,761
Ensembl chr 1:245,969,179...245,997,708
|
|
| G
|
Nol3
|
nucleolar protein 3
|
increases expression increases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of NOL3 mRNA coumarin results in increased phosphorylation of NOL3 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722
|
|
| G
|
Nol4
|
nucleolar protein 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOL4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:14,207,303...14,569,697
Ensembl chr18:14,207,303...14,569,677
|
|
| G
|
Nol4l
|
nucleolar protein 4-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOL4L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:162,345,059...162,467,849
Ensembl chr 3:162,348,211...162,468,048
|
|
| G
|
Nol8
|
nucleolar protein 8
|
increases expression decreases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of NOL8 mRNA coumarin results in decreased phosphorylation of NOL8 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr17:15,196,881...15,220,265
Ensembl chr17:15,196,881...15,220,202
|
|
| G
|
Nolc1
|
nucleolar and coiled-body phosphoprotein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NOLC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
|
|
| G
|
Nom1
|
nucleolar protein with MIF4G domain 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036
|
|
| G
|
Nop2
|
NOP2 nucleolar protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:159,618,966...159,630,697
|
|
| G
|
Nop56
|
NOP56 ribonucleoprotein
|
increases expression increases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of NOP56 mRNA coumarin results in increased phosphorylation of NOP56 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
|
|
| G
|
Nop58
|
NOP58 ribonucleoprotein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NOP58 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:68,615,010...68,638,909
|
|
| G
|
Nos1ap
|
nitric oxide synthase 1 adaptor protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOS1AP protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:85,080,558...85,353,741
Ensembl chr13:85,063,350...85,353,741
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
increases expression
|
EXP ISO
|
coumarin results in increased expression of NOS2 mRNA coumarin analog results in increased expression of NOS2 mRNA; coumarin analog results in increased expression of NOS2 protein
|
CTD |
PMID:15135310 PMID:32578917 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nosip
|
nitric oxide synthase interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOSIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:104,679,783...104,695,570
Ensembl chr 1:104,679,882...104,695,119
|
|
| G
|
Notch2
|
notch receptor 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NOTCH2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823
|
|
| G
|
Notch3
|
notch receptor 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NOTCH3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,784,272...11,834,778
|
|
| G
|
Nphp4
|
nephrocystin 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NPHP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:168,270,522...168,356,393
Ensembl chr 5:168,271,073...168,358,242
|
|
| G
|
Npm1
|
nucleophosmin 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NPM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
increases expression
|
ISO EXP
|
coumarin results in increased expression of NQO1 mRNA; coumarin results in increased expression of NQO1 protein
|
CTD |
PMID:11309284 PMID:17311802 PMID:18480146 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Nr0b2
|
nuclear receptor subfamily 0, group B, member 2
|
increases expression
|
EXP
|
coumarin results in increased expression of NR0B2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475
|
|
| G
|
Nr1d2
|
nuclear receptor subfamily 1, group D, member 2
|
increases expression
|
EXP
|
coumarin results in increased expression of NR1D2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330
|
|
| G
|
Nr2c2
|
nuclear receptor subfamily 2, group C, member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NR2C2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:126,167,350...126,223,942
Ensembl chr 4:126,168,085...126,223,942
|
|
| G
|
Nrep
|
neuronal regeneration related protein
|
decreases expression
|
EXP
|
coumarin results in decreased expression of NREP mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742
|
|
| G
|
Nrg1
|
neuregulin 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NRG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849
|
|
| G
|
Nrg3
|
neuregulin 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NRG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:14,256,540...15,374,107
Ensembl chr16:14,257,148...15,374,147
|
|
| G
|
Nrtn
|
neurturin
|
increases expression
|
EXP
|
coumarin results in increased expression of NRTN mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,641,618...1,675,133
|
|
| G
|
Nsd1
|
nuclear receptor binding SET domain protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NSD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:9,317,085...9,431,528
Ensembl chr17:9,317,085...9,452,250
|
|
| G
|
Nsd2
|
nuclear receptor binding SET domain protein 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NSD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027
|
|
| G
|
Nsd3
|
nuclear receptor binding SET domain protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NSD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:73,056,748...73,170,082
Ensembl chr16:73,061,694...73,168,130
|
|
| G
|
Nsrp1
|
nuclear speckle splicing regulatory protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NSRP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:62,378,937...62,412,601
Ensembl chr10:62,378,955...62,412,601
|
|
| G
|
Nsun2
|
NOP2/Sun RNA methyltransferase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NSUN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:35,490,583...35,514,306
|
|
| G
|
Nt5c
|
5', 3'-nucleotidase, cytosolic
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NT5C protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,238,552...101,240,666
Ensembl chr10:101,238,576...101,240,865
|
|
| G
|
Nthl1
|
nth-like DNA glycosylase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NTHL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:14,160,334...14,166,502
Ensembl chr10:14,160,330...14,166,966
|
|
| G
|
Ntng1
|
netrin G1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of NTNG1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:200,151,979...200,515,031
Ensembl chr 2:200,151,979...200,515,031
|
|
| G
|
Nuak1
|
NUAK family kinase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NUAK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:21,217,681...21,289,354
|
|
| G
|
Nucks1
|
nuclear casein kinase and cyclin-dependent kinase substrate 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NUCKS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101
|
|
| G
|
Nudc
|
nuclear distribution C, dynein complex regulator
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUDC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260
|
|
| G
|
Nudcd1
|
NudC domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NUDCD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:77,436,035...77,480,651
Ensembl chr 7:77,436,036...77,480,575
|
|
| G
|
Nufip2
|
nuclear FMR1 interacting protein 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUFIP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,072,964...63,105,823
Ensembl chr10:63,073,397...63,105,823
|
|
| G
|
Numa1
|
nuclear mitotic apparatus protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUMA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:165,709,893...165,784,848
Ensembl chr 1:165,709,905...165,784,848
|
|
| G
|
Numb
|
NUMB, endocytic adaptor protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NUMB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:109,162,499...109,284,527
Ensembl chr 6:109,162,499...109,284,463
|
|
| G
|
Nup107
|
nucleoporin 107
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUP107 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:55,239,610...55,285,050
Ensembl chr 7:55,239,613...55,285,234
|
|
| G
|
Nup153
|
nucleoporin 153
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NUP153 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:18,178,434...18,231,109
Ensembl chr17:18,178,456...18,231,109
|
|
| G
|
Nup155
|
nucleoporin 155
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NUP155 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:58,927,171...58,980,162
Ensembl chr 2:58,928,537...58,981,242
|
|
| G
|
Nup188
|
nucleoporin 188
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUP188 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:33,957,778...34,014,122
Ensembl chr 3:33,957,791...34,014,122
|
|
| G
|
Nup214
|
nucleoporin 214
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NUP214 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:35,652,841...35,738,323
Ensembl chr 3:35,652,858...35,739,192
|
|
| G
|
Nup35
|
nucleoporin 35
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NUP35 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:85,965,907...85,991,659
Ensembl chr 3:85,945,080...85,992,027
|
|
| G
|
Nup42
|
nucleoporin 42
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUP42 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:11,877,957...11,894,991
Ensembl chr 4:11,877,957...11,894,991
|
|
| G
|
Nup50
|
nucleoporin 50
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NUP50 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:117,927,882...117,945,155
Ensembl chr 7:117,925,716...117,946,959
|
|
| G
|
Nup85
|
nucleoporin 85
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of NUP85 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,305,241...101,323,980
Ensembl chr10:101,305,390...101,324,641
|
|
| G
|
Nup93
|
nucleoporin 93
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NUP93 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:10,690,154...10,793,937
Ensembl chr19:10,687,115...10,793,380
|
|
| G
|
Nup98
|
nucleoporin 98 and 96 precursor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NUP98 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:165,906,405...166,003,366
Ensembl chr 1:165,906,405...166,003,366
|
|
| G
|
Nupr1
|
nuclear protein 1, transcriptional regulator
|
increases expression
|
EXP
|
coumarin results in increased expression of NUPR1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901
|
|
| G
|
Nvl
|
nuclear VCP-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of NVL protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:95,385,389...95,438,490
Ensembl chr13:95,372,641...95,442,291
|
|
| G
|
Nyap2
|
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of NYAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:89,855,109...90,133,466
Ensembl chr 9:89,855,874...90,132,061
|
|
| G
|
Oaf
|
out at first homolog
|
decreases expression
|
EXP
|
coumarin results in decreased expression of OAF mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
|
|
| G
|
Oat
|
ornithine aminotransferase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of OAT mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
|
|
| G
|
Obsl1
|
obscurin like cytoskeletal adaptor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of OBSL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:84,416,447...84,442,415
Ensembl chr 9:84,416,240...84,442,415
|
|
| G
|
Ofd1
|
Ofd1 centriole and centriolar satellite protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of OFD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:31,647,000...31,687,768
Ensembl chr X:31,647,000...31,687,884
|
|
| G
|
Ogfr
|
opioid growth factor receptor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of OGFR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,080,743...188,087,028
Ensembl chr 3:188,080,042...188,087,471
|
|
| G
|
Ogn
|
osteoglycin
|
decreases expression
|
EXP
|
coumarin results in decreased expression of OGN mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252
|
|
| G
|
Oip5
|
Opa interacting protein 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of OIP5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:127,047,559...127,057,043
Ensembl chr 3:127,047,559...127,057,043
|
|
| G
|
Orc1
|
origin recognition complex, subunit 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ORC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:128,552,975...128,581,943
Ensembl chr 5:128,552,991...128,577,071
|
|
| G
|
Orc2
|
origin recognition complex, subunit 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ORC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:67,496,097...67,532,548
Ensembl chr 9:67,496,825...67,526,649
|
|
| G
|
Osbp
|
oxysterol binding protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of OSBP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:218,313,455...218,343,263
Ensembl chr 1:218,313,148...218,343,258
|
|
| G
|
Osbpl8
|
oxysterol binding protein-like 8
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of OSBPL8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:48,483,259...48,636,151
Ensembl chr 7:48,483,022...48,636,151
|
|
| G
|
Otub1
|
OTU deubiquitinase, ubiquitin aldehyde binding 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of OTUB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679
|
|
| G
|
Otud5
|
OTU deubiquitinase 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of OTUD5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:17,296,750...17,331,257
Ensembl chr X:17,298,029...17,331,054
|
|
| G
|
P2ry10
|
P2Y receptor family member 10
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of P2RY10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:76,184,064...76,279,996
Ensembl chr X:76,184,001...76,280,953
|
|
| G
|
P4htm
|
prolyl 4-hydroxylase, transmembrane
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of P4HTM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:118,153,158...118,172,199
Ensembl chr 8:118,153,158...118,171,002
|
|
| G
|
Pabir1
|
PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PABIR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:231,541,411...231,542,717
Ensembl chr 1:231,537,357...231,612,411
|
|
| G
|
Pabir2
|
PABIR family member 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PABIR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:137,908,653...137,935,153
Ensembl chr X:137,908,653...137,934,600
|
|
| G
|
Pacc1
|
proton activated chloride channel 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PACC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:105,435,772...105,460,877
Ensembl chr13:105,435,799...105,461,095
|
|
| G
|
Pacsin3
|
protein kinase C and casein kinase substrate in neurons 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PACSIN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:97,683,054...97,691,619
Ensembl chr 3:97,679,244...97,691,628
|
|
| G
|
Pafah1b2
|
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PAFAH1B2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:55,156,778...55,208,800
Ensembl chr 8:55,156,779...55,176,836
|
|
| G
|
Pagr1
|
Paxip1-associated glutamate-rich protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PAGR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,053,228...191,055,554
|
|
| G
|
Paics
|
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PAICS protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
|
|
| G
|
Pak2
|
p21 (RAC1) activated kinase 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PAK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803
|
|
| G
|
Pak3
|
p21 (RAC1) activated kinase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PAK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:111,912,967...112,171,037
Ensembl chr X:111,913,059...112,165,035
|
|
| G
|
Pak4
|
p21 (RAC1) activated kinase 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PAK4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:92,977,437...93,016,721
Ensembl chr 1:92,977,437...93,016,721
|
|
| G
|
Pakap
|
paralemmin A kinase anchor protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PALM2AKAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656
|
|
| G
|
Palld
|
palladin, cytoskeletal associated protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PALLD protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:33,238,943...33,632,236
Ensembl chr16:33,238,956...33,632,232
|
|
| G
|
Palm
|
paralemmin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PALM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:10,537,277...10,563,007
|
|
| G
|
Palmd
|
palmdelphin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PALMD protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:207,574,249...207,626,239
|
|
| G
|
Pals1
|
protein associated with LIN7 1, MAGUK p55 family member
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PALS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:103,327,965...103,384,543
Ensembl chr 6:103,281,154...103,387,209
|
|
| G
|
Pank1
|
pantothenate kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PANK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824
|
|
| G
|
Pard3
|
par-3 family cell polarity regulator
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PARD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941
|
|
| G
|
Parg
|
poly (ADP-ribose) glycohydrolase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PARG protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
decreases activity decreases expression increases cleavage multiple interactions
|
ISO
|
coumarin results in decreased activity of PARP1 protein coumarin analog results in decreased expression of PARP1 mRNA coumarin analog results in increased cleavage of PARP1 protein [coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]; [coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]
|
CTD |
PMID:17669606 PMID:31199928 PMID:32578917 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Parp16
|
poly (ADP-ribose) polymerase family, member 16
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PARP16 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:74,626,399...74,644,610
Ensembl chr 8:74,622,878...74,644,612
|
|
| G
|
Parva
|
parvin, alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PARVA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:175,981,725...176,139,523
Ensembl chr 1:175,981,432...176,139,526
|
|
| G
|
Paxip1
|
PAX interacting protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PAXIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:8,258,930...8,310,490
Ensembl chr 4:8,258,952...8,310,488
|
|
| G
|
Pbk
|
PDZ binding kinase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PBK protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570
|
|
| G
|
Pbrm1
|
polybromo 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PBRM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:6,219,933...6,319,336
Ensembl chr16:6,219,917...6,319,336
|
|
| G
|
Pbx2
|
PBX homeobox 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PBX2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:4,156,107...4,161,503
Ensembl chr20:4,156,107...4,161,827
|
|
| G
|
Pbxip1
|
PBX homeobox interacting protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PBXIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:177,154,056...177,167,810
Ensembl chr 2:177,154,101...177,167,328
|
|
| G
|
Pcbp1
|
poly(rC) binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PCBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:120,529,172...120,539,111
|
|
| G
|
Pcbp2
|
poly(rC) binding protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PCBP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412
|
|
| G
|
Pcdh15
|
protocadherin related 15
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PCDH15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958
|
|
| G
|
Pcf11
|
PCF11 cleavage and polyadenylation factor subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PCF11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:156,109,724...156,136,950
Ensembl chr 1:156,109,724...156,136,435
|
|
| G
|
Pcgf6
|
polycomb group ring finger 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PCGF6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:255,866,709...255,886,306
Ensembl chr 1:255,866,711...255,886,266
|
|
| G
|
Pcif1
|
phosphorylated CTD interacting factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PCIF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:174,033,471...174,046,403
Ensembl chr 3:174,034,675...174,049,395
|
|
| G
|
Pck2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
increases expression
|
EXP
|
coumarin results in increased expression of PCK2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
|
|
| G
|
Pcm1
|
pericentriolar material 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PCM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:57,711,833...57,808,842
Ensembl chr16:57,711,833...57,808,599
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
increases expression
|
ISO
|
coumarin analog results in increased expression of PCNA mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pcnx2
|
pecanex 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PCNX2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:70,616,240...70,766,869
Ensembl chr19:70,616,240...70,766,869
|
|
| G
|
Pcyox1
|
prenylcysteine oxidase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PCYOX1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:120,389,545...120,400,382
Ensembl chr 4:120,388,180...120,400,382
|
|
| G
|
Pdcd11
|
programmed cell death 11
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PDCD11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:255,922,198...255,963,336
Ensembl chr 1:255,922,225...255,963,336
|
|
| G
|
Pdcd4
|
programmed cell death 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PDCD4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
|
|
| G
|
Pde3a
|
phosphodiesterase 3A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PDE3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270
|
|
| G
|
Pde4b
|
phosphodiesterase 4B
|
decreases expression
|
EXP
|
coumarin results in decreased expression of PDE4B mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267
|
|
| G
|
Pde4d
|
phosphodiesterase 4D
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PDE4D protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:42,110,838...43,262,569
|
|
| G
|
Pde7b
|
phosphodiesterase 7B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PDE7B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456
|
|
| G
|
Pde8a
|
phosphodiesterase 8A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PDE8A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:144,575,203...144,698,216
Ensembl chr 1:144,575,428...144,698,215
|
|
| G
|
Pdia3
|
protein disulfide isomerase family A, member 3
|
increases expression
|
EXP
|
coumarin results in increased expression of PDIA3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
|
|
| G
|
Pdia4
|
protein disulfide isomerase family A, member 4
|
increases expression
|
EXP
|
coumarin results in increased expression of PDIA4 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191
|
|
| G
|
Pdk2
|
pyruvate dehydrogenase kinase 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of PDK2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355
|
|
| G
|
Pdlim1
|
PDZ and LIM domain 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PDLIM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379
|
|
| G
|
Pdlim2
|
PDZ and LIM domain 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PDLIM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:51,647,195...51,659,904
Ensembl chr15:51,647,197...51,658,958
|
|
| G
|
Pdlim5
|
PDZ and LIM domain 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PDLIM5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:233,625,478...233,793,582
Ensembl chr 2:233,628,503...233,793,528
|
|
| G
|
Pds5a
|
PDS5 cohesin associated factor A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PDS5A protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:42,905,734...43,004,740
Ensembl chr14:42,905,328...43,004,740
|
|
| G
|
Pds5b
|
PDS5 cohesin associated factor B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PDS5B protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:5,038,114...5,181,208
Ensembl chr12:5,038,160...5,181,208
|
|
| G
|
Pdxdc1
|
pyridoxal-dependent decarboxylase domain containing 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PDXDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:2,528,989...2,620,669
Ensembl chr10:2,532,485...2,620,669
|
|
| G
|
Pdzrn4
|
PDZ domain containing RING finger 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PDZRN4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:125,696,448...125,844,965
Ensembl chr 7:125,696,448...125,844,965
|
|
| G
|
Peak1
|
pseudopodium-enriched atypical kinase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PEAK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:65,501,068...65,715,768
Ensembl chr 8:65,505,043...65,715,111
|
|
| G
|
Pelp1
|
proline, glutamate and leucine rich protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PELP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:55,593,444...55,610,478
Ensembl chr10:55,593,447...55,610,758
|
|
| G
|
Pex1
|
peroxisomal biogenesis factor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PEX1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:31,474,670...31,513,621
Ensembl chr 4:31,470,845...31,513,811
|
|
| G
|
Pex14
|
peroxisomal biogenesis factor 14
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PEX14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:164,682,876...164,819,352
Ensembl chr 5:164,682,715...164,819,352
|
|
| G
|
Pex19
|
peroxisomal biogenesis factor 19
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PEX19 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:87,124,654...87,141,170
Ensembl chr13:87,124,698...87,141,757
|
|
| G
|
Pfkfb2
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PFKFB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:44,683,499...44,727,135
Ensembl chr13:44,699,744...44,726,971
|
|
| G
|
Pfkfb3
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PFKFB3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052
|
|
| G
|
Pgk1
|
phosphoglycerate kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PGK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
|
|
| G
|
Pgm1
|
phosphoglucomutase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PGM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159
|
|
| G
|
Pgrmc1
|
progesterone receptor membrane component 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PGRMC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
|
|
| G
|
Phactr4
|
phosphatase and actin regulator 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PHACTR4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:149,828,716...149,904,955
Ensembl chr 5:149,833,367...149,905,187
|
|
| G
|
Phax
|
phosphorylated adaptor for RNA export
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PHAX protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:52,251,231...52,267,916
Ensembl chr18:52,248,709...52,267,915
|
|
| G
|
Phc1
|
polyhomeotic homolog 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PHC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:157,182,348...157,205,504
Ensembl chr 4:157,182,348...157,204,709
|
|
| G
|
Phc3
|
polyhomeotic homolog 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PHC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:114,337,180...114,412,132
Ensembl chr 2:114,337,227...114,405,816
|
|
| G
|
Phf10
|
PHD finger protein 10
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PHF10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:64,625,373...64,642,110
Ensembl chr 1:64,624,465...64,642,049
|
|
| G
|
Phf12
|
PHD finger protein 12
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PHF12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,368,547...63,417,079
Ensembl chr10:63,370,210...63,417,073
|
|
| G
|
Phf14
|
PHD finger protein 14
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PHF14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:40,975,897...41,162,043
Ensembl chr 4:40,975,439...41,162,043
|
|
| G
|
Phf2
|
PHD finger protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PHF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:15,989,594...16,057,583
Ensembl chr17:15,981,604...16,057,583
|
|
| G
|
Phf23
|
PHD finger protein 23
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PHF23 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:55,217,351...55,221,471
Ensembl chr10:55,217,351...55,221,471
|
|
| G
|
Phf8
|
PHD finger protein 8
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PHF8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:23,967,126...24,066,473
Ensembl chr X:23,967,556...24,066,471
|
|
| G
|
Phip
|
pleckstrin homology domain interacting protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PHIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:92,656,890...92,771,098
Ensembl chr 8:92,656,890...92,771,021
|
|
| G
|
Phka1
|
phosphorylase kinase regulatory subunit alpha 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PHKA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:71,639,701...71,778,465
Ensembl chr X:71,641,246...71,778,320
|
|
| G
|
Phka2
|
phosphorylase kinase regulatory subunit alpha 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PHKA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:37,979,629...38,102,656
Ensembl chr X:37,979,629...38,102,144
|
|
| G
|
Phldb1
|
pleckstrin homology-like domain, family B, member 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PHLDB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:53,900,338...53,948,325
Ensembl chr 8:53,900,338...53,949,518
|
|
| G
|
Phldb2
|
pleckstrin homology-like domain, family B, member 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PHLDB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734
|
|
| G
|
Pi4ka
|
phosphatidylinositol 4-kinase alpha
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PI4KA protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:97,113,390...97,234,374
Ensembl chr11:97,113,245...97,228,315
|
|
| G
|
Pi4kb
|
phosphatidylinositol 4-kinase beta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PI4KB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:185,229,392...185,261,697
Ensembl chr 2:185,228,799...185,261,693
|
|
| G
|
Pias1
|
protein inhibitor of activated STAT, 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PIAS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:72,233,566...72,334,315
|
|
| G
|
Picalm
|
phosphatidylinositol binding clathrin assembly protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PICALM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:153,468,982...153,550,086
Ensembl chr 1:153,469,202...153,550,237
|
|
| G
|
Pimreg
|
PICALM interacting mitotic regulator
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PIMREG protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:57,168,136...57,173,713
Ensembl chr10:57,167,797...57,173,063
|
|
| G
|
Pip4p1
|
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PIP4P1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:26,620,399...26,624,369
Ensembl chr15:26,620,401...26,624,246
|
|
| G
|
Pja1
|
praja ring finger ubiquitin ligase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PJA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:68,621,101...68,626,001
Ensembl chr X:68,620,084...68,638,407
|
|
| G
|
Pkm
|
pyruvate kinase M1/2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PKM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
|
|
| G
|
Pkn1
|
protein kinase N1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PKN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:41,346,855...41,374,832
Ensembl chr19:41,346,860...41,378,395
|
|
| G
|
Pkn2
|
protein kinase N2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PKN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:234,454,001...234,559,369
Ensembl chr 2:234,454,001...234,594,649
|
|
| G
|
Pkp2
|
plakophilin 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PKP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:98,165,974...98,231,916
Ensembl chr11:98,165,974...98,231,916
|
|
| G
|
Pkp3
|
plakophilin 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PKP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:205,617,511...205,628,441
Ensembl chr 1:205,617,511...205,628,440
|
|
| G
|
Pkp4
|
plakophilin 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PKP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:64,040,995...64,244,586
Ensembl chr 3:64,141,771...64,244,586
|
|
| G
|
Pla2g12a
|
phospholipase A2, group XIIA
|
increases expression
|
EXP
|
coumarin results in increased expression of PLA2G12A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964
|
|
| G
|
Pla2g3
|
phospholipase A2, group III
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLA2G3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542
|
|
| G
|
Plagl1
|
PLAG1 like zinc finger 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLAGL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:9,297,066...9,337,394
Ensembl chr 1:9,330,204...9,337,394
|
|
| G
|
Plagl2
|
PLAG1 like zinc finger 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PLAGL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:162,155,554...162,168,748
Ensembl chr 3:162,155,554...162,168,748
|
|
| G
|
Plcd3
|
phospholipase C, delta 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLCD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:88,526,802...88,548,116
Ensembl chr10:88,526,802...88,548,069
|
|
| G
|
Plcl2
|
phospholipase C-like 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PLCL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:3,529,117...3,713,712
Ensembl chr 9:3,529,841...3,713,712
|
|
| G
|
Plec
|
plectin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PLEC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:109,768,447...109,828,089
|
|
| G
|
Plekha5
|
pleckstrin homology domain containing A5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLEKHA5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:175,065,011...175,234,672
Ensembl chr 4:175,065,183...175,234,672
|
|
| G
|
Plekhg2
|
pleckstrin homology and RhoGEF domain containing G2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PLEKHG2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:92,779,449...92,792,610
Ensembl chr 1:92,779,449...92,792,610
|
|
| G
|
Plekhg3
|
pleckstrin homology and RhoGEF domain containing G3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PLEKHG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:100,998,965...101,042,120
Ensembl chr 6:100,994,417...101,042,118
|
|
| G
|
Plekhg4
|
pleckstrin homology and RhoGEF domain containing G4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLEKHG4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:50,161,722...50,176,491
Ensembl chr19:50,159,754...50,182,133
|
|
| G
|
Plekhm2
|
pleckstrin homology and RUN domain containing M2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PLEKHM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:159,222,620...159,261,666
Ensembl chr 5:159,223,300...159,261,642
|
|
| G
|
Plk1
|
polo-like kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
|
|
| G
|
Plk2
|
polo-like kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PLK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296
|
|
| G
|
Plod1
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PLOD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110
|
|
| G
|
Pls3
|
plastin 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PLS3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893
|
|
| G
|
Pml
|
PML nuclear body scaffold
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PML protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
|
|
| G
|
Pnn
|
pinin, desmosome associated protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PNN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933
|
|
| G
|
Pnpla6
|
patatin-like phospholipase domain containing 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PNPLA6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:6,372,284...6,401,632
Ensembl chr12:6,372,293...6,401,631
|
|
| G
|
Pogz
|
pogo transposable element derived with ZNF domain
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of POGZ protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:185,069,492...185,129,741
Ensembl chr 2:185,084,826...185,129,739
|
|
| G
|
Pola2
|
DNA polymerase alpha 2, accessory subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POLA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,656,500...212,680,667
Ensembl chr 1:212,656,501...212,680,542
|
|
| G
|
Pold1
|
DNA polymerase delta 1, catalytic subunit
|
increases expression
|
EXP
|
coumarin results in increased expression of POLD1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982
|
|
| G
|
Pold2
|
DNA polymerase delta 2, accessory subunit
|
increases expression
|
EXP
|
coumarin results in increased expression of POLD2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr14:84,962,933...84,969,148
Ensembl chr14:84,962,022...84,967,874
|
|
| G
|
Poldip2
|
DNA polymerase delta interacting protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POLDIP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,905,287...63,915,655
Ensembl chr10:63,904,691...63,915,655
|
|
| G
|
Poldip3
|
DNA polymerase delta interacting protein 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POLDIP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:116,154,892...116,183,319
Ensembl chr 7:116,154,892...116,183,300
|
|
| G
|
Pole4
|
DNA polymerase epsilon 4, accessory subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of POLE4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:116,723,040...116,728,873
Ensembl chr 4:116,716,719...116,728,851
|
|
| G
|
Polg2
|
DNA polymerase gamma 2, accessory subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POLG2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:92,212,303...92,222,849
Ensembl chr10:92,212,304...92,222,726
|
|
| G
|
Polm
|
DNA polymerase mu
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POLM protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:84,921,039...84,930,649
Ensembl chr14:84,921,045...84,930,622
|
|
| G
|
Polr1e
|
RNA polymerase I subunit E
|
increases expression
|
EXP
|
coumarin results in increased expression of POLR1E mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:64,075,123...64,090,900
Ensembl chr 5:64,075,122...64,091,039
|
|
| G
|
Polr1f
|
RNA polymerase I subunit F
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POLR1F protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:55,780,706...55,797,935
Ensembl chr 6:55,780,706...55,797,935
|
|
| G
|
Polr1g
|
RNA polymerase I subunit G
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of POLR1G protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:88,135,493...88,138,769
Ensembl chr 1:88,135,493...88,138,769
|
|
| G
|
Polr2a
|
RNA polymerase II subunit A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of POLR2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,951,162...54,977,179
|
|
| G
|
Pom121
|
POM121 transmembrane nucleoporin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POM121 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:26,913,513...26,930,861
Ensembl chr12:26,913,513...26,930,861
|
|
| G
|
Pop1
|
POP1 homolog, ribonuclease P/MRP subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of POP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:67,590,502...67,618,187
Ensembl chr 7:67,590,522...67,618,293
|
|
| G
|
Ppfia1
|
PTPRF interacting protein alpha 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPFIA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:209,070,608...209,147,740
Ensembl chr 1:209,070,608...209,150,265
|
|
| G
|
Ppfibp1
|
PPFIA binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPFIBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:181,538,249...181,682,079
Ensembl chr 4:181,539,450...181,682,076
|
|
| G
|
Pphln1
|
periphilin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPHLN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:126,418,042...126,509,430
Ensembl chr 7:126,417,555...126,509,430
|
|
| G
|
Ppig
|
peptidylprolyl isomerase G
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPIG protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:74,891,846...74,923,010
Ensembl chr 3:74,891,846...74,920,750
|
|
| G
|
Ppil4
|
peptidylprolyl isomerase like 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PPIL4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:4,093,956...4,126,016
Ensembl chr 1:4,093,977...4,126,016
|
|
| G
|
Ppm1d
|
protein phosphatase, Mg2+/Mn2+ dependent, 1D
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPM1D protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256
|
|
| G
|
Ppp1r10
|
protein phosphatase 1, regulatory subunit 10
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP1R10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418
|
|
| G
|
Ppp1r12a
|
protein phosphatase 1, regulatory subunit 12A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPP1R12A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157
|
|
| G
|
Ppp1r12c
|
protein phosphatase 1, regulatory subunit 12C
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPP1R12C protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:78,362,900...78,385,873
Ensembl chr 1:78,362,928...78,385,873
|
|
| G
|
Ppp1r13l
|
protein phosphatase 1, regulatory subunit 13 like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP1R13L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:88,139,000...88,158,714
Ensembl chr 1:88,140,532...88,158,714
|
|
| G
|
Ppp1r15b
|
protein phosphatase 1, regulatory subunit 15B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PPP1R15B protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:47,130,000...47,137,805
Ensembl chr13:47,129,967...47,137,798
|
|
| G
|
Ppp1r2
|
protein phosphatase 1, regulatory (inhibitor) subunit 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPP1R2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:82,977,634...82,999,426
Ensembl chr11:82,977,515...83,001,083
|
|
| G
|
Ppp1r37
|
protein phosphatase 1, regulatory subunit 37
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PPP1R37 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:88,308,782...88,340,796
Ensembl chr 1:88,308,782...88,340,592
|
|
| G
|
Ppp1r9a
|
protein phosphatase 1, regulatory subunit 9A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP1R9A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927
|
|
| G
|
Ppp1r9b
|
protein phosphatase 1, regulatory subunit 9B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP1R9B protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:80,434,888...80,450,919
Ensembl chr10:80,434,900...80,450,919
|
|
| G
|
Ppp2r5d
|
protein phosphatase 2, regulatory subunit B', delta
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP2R5D protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:21,767,963...21,797,997
Ensembl chr 9:21,767,688...21,797,996
|
|
| G
|
Ppp2r5e
|
protein phosphatase 2 regulatory subunit B', epsilon
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP2R5E protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573
|
|
| G
|
Ppp4r2
|
protein phosphatase 4, regulatory subunit 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PPP4R2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:135,010,919...135,051,844
Ensembl chr 4:135,010,919...135,051,844
|
|
| G
|
Ppp5c
|
protein phosphatase 5, catalytic subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PPP5C protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950
|
|
| G
|
Ppp6r3
|
protein phosphatase 6, regulatory subunit 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PPP6R3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:210,122,394...210,236,839
Ensembl chr 1:210,122,394...210,236,809
|
|
| G
|
Prag1
|
PEAK1 related kinase activating pseudokinase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PRAG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:62,791,249...62,844,532
Ensembl chr16:62,786,329...62,844,532
|
|
| G
|
Prc1
|
protein regulator of cytokinesis 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
|
|
| G
|
Prdm1
|
PR/SET domain 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRDM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088
|
|
| G
|
Prickle1
|
prickle planar cell polarity protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRICKLE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:126,518,587...126,614,581
|
|
| G
|
Prkaa1
|
protein kinase AMP-activated catalytic subunit alpha 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKAA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
|
|
| G
|
Prkab2
|
protein kinase AMP-activated non-catalytic subunit beta 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PRKAB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:187,945,982...187,961,608
|
|
| G
|
Prkacb
|
protein kinase cAMP-activated catalytic subunit beta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKACB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315
|
|
| G
|
Prkar1a
|
protein kinase cAMP-dependent type I regulatory subunit alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKAR1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025
|
|
| G
|
Prkar1b
|
protein kinase cAMP-dependent type I regulatory subunit beta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKAR1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766
|
|
| G
|
Prkca
|
protein kinase C, alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKCA protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
|
|
| G
|
Prkcd
|
protein kinase C, delta
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRKCD protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839
|
|
| G
|
Prkch
|
protein kinase C, eta
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRKCH protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:98,027,646...98,226,477
|
|
| G
|
Prkci
|
protein kinase C, iota
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRKCI protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:114,250,398...114,310,784
|
|
| G
|
Prkd2
|
protein kinase D2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRKD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:86,642,629...86,670,675
|
|
| G
|
Prkd3
|
protein kinase D3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:21,784,665...21,860,600
Ensembl chr 6:21,784,673...21,860,600
|
|
| G
|
Prkdc
|
protein kinase, DNA-activated, catalytic subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKDC protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108
|
|
| G
|
Prkra
|
protein activator of interferon induced protein kinase EIF2AK2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRKRA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:81,982,669...82,002,028
Ensembl chr 3:81,982,673...82,001,525
|
|
| G
|
Proser2
|
proline and serine rich 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PROSER2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:77,061,371...77,096,788
Ensembl chr17:77,077,727...77,095,194
|
|
| G
|
Prp2
|
proline rich protein 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of PRP2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:167,331,491...167,335,068
Ensembl chr 4:167,331,491...167,335,068
|
|
| G
|
Prpf31
|
pre-mRNA processing factor 31
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRPF31 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:74,491,247...74,502,922
Ensembl chr 1:74,491,247...74,502,922
|
|
| G
|
Prpf38b
|
pre-mRNA processing factor 38B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRPF38B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:199,241,312...199,250,342
Ensembl chr 2:199,241,313...199,250,338
|
|
| G
|
Prpf40a
|
pre-mRNA processing factor 40 homolog A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PRPF40A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:58,036,779...58,098,996
Ensembl chr 3:58,038,042...58,099,363
|
|
| G
|
Prpf40b
|
pre-mRNA processing factor 40 homolog B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRPF40B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:132,271,469...132,332,913
Ensembl chr 7:132,310,927...132,332,912
|
|
| G
|
Prpf4b
|
pre-mRNA processing factor 4B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRP4K protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:30,190,721...30,230,153
Ensembl chr17:30,193,907...30,225,420
|
|
| G
|
Prpf6
|
pre-mRNA processing factor 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRPF6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:189,084,465...189,148,705
Ensembl chr 3:189,081,794...189,152,786
|
|
| G
|
Prpsap1
|
phosphoribosyl pyrophosphate synthetase-associated protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PRPSAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
|
|
| G
|
Prr11
|
proline rich 11
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRR11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:72,396,127...72,440,643
Ensembl chr10:72,398,667...72,418,275
|
|
| G
|
Prr12
|
proline rich 12
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRR12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:104,646,492...104,670,454
Ensembl chr 1:104,646,492...104,670,454
|
|
| G
|
Prr14l
|
proline rich 14-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRR14L protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:82,094,360...82,160,985
Ensembl chr14:82,094,358...82,158,323
|
|
| G
|
Prr5
|
proline rich 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRR5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:117,675,308...117,717,833
Ensembl chr 7:117,675,383...117,717,831
|
|
| G
|
Prr5l
|
proline rich 5 like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PRR5L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:108,458,107...108,628,552
Ensembl chr 3:108,458,633...108,537,763
|
|
| G
|
Prrc2a
|
proline-rich coiled-coil 2A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PRRC2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:3,660,981...3,686,715
Ensembl chr20:3,663,400...3,678,778
|
|
| G
|
Prrc2b
|
proline-rich coiled-coil 2B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRRC2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:35,831,017...35,916,854
Ensembl chr 3:35,863,046...35,916,854
|
|
| G
|
Prrc2c
|
proline-rich coiled-coil 2C
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PRRC2C protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:77,537,226...77,606,926
Ensembl chr13:77,537,814...77,607,001
|
|
| G
|
Prxl2c
|
peroxiredoxin like 2C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PRXL2C protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:817,932...849,965
Ensembl chr17:817,949...840,940
|
|
| G
|
Psen2
|
presenilin 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PSEN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116
|
|
| G
|
Psip1
|
PC4 and SRSF1 interacting protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PSIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:102,892,929...102,925,191
Ensembl chr 5:102,892,932...102,925,170
|
|
| G
|
Psma5
|
proteasome 20S subunit alpha 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PSMA5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867
|
|
| G
|
Psmc3
|
proteasome 26S subunit, ATPase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PSMC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176
|
|
| G
|
Ptbp1
|
polypyrimidine tract binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PTBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:10,493,199...10,502,957
Ensembl chr 7:10,493,200...10,502,957
|
|
| G
|
Ptdss1
|
phosphatidylserine synthase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PTDSS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:65,730,250...65,792,024
Ensembl chr 7:65,729,629...65,794,359
|
|
| G
|
Ptgr1
|
prostaglandin reductase 1
|
increases expression
|
EXP
|
coumarin results in increased expression of PTGR1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811
|
|
| G
|
Ptpn2
|
protein tyrosine phosphatase, non-receptor type 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PTPN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481
|
|
| G
|
Ptpn3
|
protein tyrosine phosphatase, non-receptor type 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PTPN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:76,703,687...76,822,584
Ensembl chr 5:76,703,687...76,860,470
|
|
| G
|
Ptpn6
|
protein tyrosine phosphatase, non-receptor type 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PTPN6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069
|
|
| G
|
Ptprf
|
protein tyrosine phosphatase, receptor type, F
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PTPRF protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
|
|
| G
|
Ptprk
|
protein tyrosine phosphatase, receptor type, K
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PTPRK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:18,557,091...19,056,297
Ensembl chr 1:18,558,365...19,056,107
|
|
| G
|
Ptrh2
|
peptidyl-tRNA hydrolase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PTRH2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:72,002,450...72,012,606
Ensembl chr10:71,985,245...72,045,352
|
|
| G
|
Pts
|
6-pyruvoyl-tetrahydropterin synthase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PTS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:59,767,234...59,774,265
Ensembl chr 8:59,765,185...59,774,265
|
|
| G
|
Pum1
|
pumilio RNA-binding family member 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PUM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:148,120,712...148,238,468
Ensembl chr 5:148,121,254...148,238,466
|
|
| G
|
Pum2
|
pumilio RNA-binding family member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PUM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:37,182,130...37,262,223
Ensembl chr 6:37,182,013...37,262,223
|
|
| G
|
Purb
|
purine rich element binding protein B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PURB protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:85,556,296...85,558,779
Ensembl chr14:85,550,417...85,572,205
|
|
| G
|
Pus1
|
pseudouridine synthase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PUS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:51,539,659...51,548,975
Ensembl chr12:51,540,212...51,548,973
|
|
| G
|
Pus7
|
pseudouridine synthase 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of PUS7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:12,252,553...12,293,547
Ensembl chr 4:12,252,545...12,293,539
|
|
| G
|
Pus7l
|
pseudouridine synthase 7 like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PUS7L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:127,538,785...127,561,936
Ensembl chr 7:127,538,558...127,561,798
|
|
| G
|
Pwp2
|
PWP2, small subunit processome component
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PWP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:10,498,998...10,512,631
Ensembl chr20:10,499,013...10,513,309
|
|
| G
|
Pxn
|
paxillin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of PXN protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:46,721,546...46,768,706
Ensembl chr12:46,721,546...46,768,697
|
|
| G
|
Pxylp1
|
2-phosphoxylose phosphatase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of PXYLP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:106,299,303...106,364,603
Ensembl chr 8:106,299,304...106,364,603
|
|
| G
|
Qser1
|
glutamine and serine rich 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of QSER1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:111,592,377...111,658,825
Ensembl chr 3:111,595,171...111,657,103
|
|
| G
|
R3hdm1
|
R3H domain containing 1
|
increases phosphorylation increases expression
|
ISO EXP
|
coumarin results in increased phosphorylation of R3HDM1 protein coumarin results in increased expression of R3HDM1 mRNA
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr13:42,148,281...42,286,311
Ensembl chr13:42,148,290...42,286,311
|
|
| G
|
R3hdm2
|
R3H domain containing 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of R3HDM2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862
|
|
| G
|
Rab11fip1
|
RAB11 family interacting protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RAB11FIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:71,589,753...71,620,341
Ensembl chr16:71,589,753...71,620,341
|
|
| G
|
Rab11fip5
|
RAB11 family interacting protein 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RAB11FIP5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:119,428,766...119,466,277
Ensembl chr 4:119,428,766...119,466,213
|
|
| G
|
Rab2b
|
RAB2B, member RAS oncogene family
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RAB2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:27,441,860...27,462,479
Ensembl chr15:27,442,816...27,462,479
|
|
| G
|
Rab3d
|
RAB3D, member RAS oncogene family
|
increases expression
|
EXP
|
coumarin results in increased expression of RAB3D mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:28,714,706...28,725,379
Ensembl chr 8:28,716,241...28,725,317
|
|
| G
|
Rab3il1
|
RAB3A interacting protein-like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RAB3IL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:216,071,043...216,107,609
Ensembl chr 1:216,071,084...216,107,609
|
|
| G
|
Rab3ip
|
RAB3A interacting protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAB3IP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:54,417,418...54,461,253
Ensembl chr 7:54,418,358...54,447,000
|
|
| G
|
Rab42
|
RAB42, member RAS oncogene family
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RAB42 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:149,781,181...149,782,851
Ensembl chr 5:149,781,181...149,782,851
|
|
| G
|
Rab9a
|
RAB9A, member RAS oncogene family
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RAB9A protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:31,610,089...31,632,128
Ensembl chr X:31,583,944...31,645,743
|
|
| G
|
Rabep1
|
rabaptin, RAB GTPase binding effector protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RABEP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177
|
|
| G
|
Rabgef1
|
RAB guanine nucleotide exchange factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RABGEF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:32,096,338...32,139,949
Ensembl chr12:32,096,338...32,139,040
|
|
| G
|
Rabl6
|
RAB, member RAS oncogene family-like 6
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RABL6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:28,800,802...28,826,722
Ensembl chr 3:28,800,802...28,826,722
|
|
| G
|
Racgap1
|
Rac GTPase-activating protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RACGAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
|
|
| G
|
Rad21
|
RAD21 cohesin complex component
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RAD21 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657
|
|
| G
|
Rad23a
|
RAD23 homolog A, nucleotide excision repair protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RAD23A protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543
|
|
| G
|
Rad23b
|
RAD23 homolog B, nucleotide excision repair protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RAD23B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:74,885,518...74,923,621
Ensembl chr 5:74,885,516...74,962,426
|
|
| G
|
Rad9a
|
RAD9 checkpoint clamp component A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAD9A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161
|
|
| G
|
Raf1
|
Raf-1 proto-oncogene, serine/threonine kinase
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813
|
|
| G
|
Rai1
|
retinoic acid induced 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAI1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:45,412,748...45,507,747
Ensembl chr10:45,447,427...45,507,747
|
|
| G
|
Rai14
|
retinoic acid induced 14
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAI14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:61,273,439...61,411,141
Ensembl chr 2:61,273,439...61,409,791
|
|
| G
|
Ralbp1
|
ralA binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RALBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:112,903,302...112,939,659
|
|
| G
|
Ralgapa1
|
Ral GTPase activating protein catalytic subunit alpha 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RALGAPA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:78,712,554...78,987,486
Ensembl chr 6:78,701,832...78,987,486
|
|
| G
|
Ralgapb
|
Ral GTPase activating protein non-catalytic subunit beta
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RALGAPB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:167,482,344...167,571,975
Ensembl chr 3:167,482,343...167,571,815
|
|
| G
|
Ralgps2
|
Ral GEF with PH domain and SH3 binding motif 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RALGPS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:71,474,835...71,654,791
Ensembl chr13:71,474,835...71,606,739
|
|
| G
|
Ranbp2
|
RAN binding protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RANBP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571
|
|
| G
|
Ranbp3
|
RAN binding protein 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RANBP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,594,344...1,631,587
Ensembl chr 9:1,594,346...1,631,587
|
|
| G
|
Ranbp9
|
RAN binding protein 9
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RANBP9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:21,426,717...21,508,964
Ensembl chr17:21,426,777...21,508,964
|
|
| G
|
Rangap1
|
RAN GTPase activating protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RANGAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564
|
|
| G
|
Rap1gap2
|
RAP1 GTPase activating protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RAP1GAP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:59,753,822...59,970,946
Ensembl chr10:59,753,822...59,970,887
|
|
| G
|
Rapgef2
|
Rap guanine nucleotide exchange factor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAPGEF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:166,505,868...166,726,698
|
|
| G
|
Rapgef6
|
Rap guanine nucleotide exchange factor 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RAPGEF6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:39,156,573...39,324,947
Ensembl chr10:39,156,620...39,324,946
|
|
| G
|
Raph1
|
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RAPH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:69,397,272...69,484,174
Ensembl chr 9:69,401,517...69,484,019
|
|
| G
|
Rasal2
|
RAS protein activator like 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RASAL2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:71,808,740...72,102,723
Ensembl chr13:71,813,261...72,102,723
|
|
| G
|
Rassf8
|
Ras association domain family member 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RASSF8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:180,447,050...180,528,792
Ensembl chr 4:180,446,846...180,528,790
|
|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
|
|
| G
|
Rbbp5
|
RB binding protein 5, histone lysine methyltransferase complex subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBBP5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:46,464,389...46,494,244
Ensembl chr13:46,464,389...46,491,238
|
|
| G
|
Rbbp6
|
RB binding protein 6, ubiquitin ligase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBBP6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:186,934,563...186,966,852
Ensembl chr 1:186,934,938...186,966,852
|
|
| G
|
Rbbp8
|
RB binding protein 8, endonuclease
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBBP8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:3,198,188...3,263,643
Ensembl chr18:3,197,310...3,263,985
|
|
| G
|
Rbbp8nl
|
RBBP8 N-terminal like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RBBP8NL protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:187,741,642...187,756,598
Ensembl chr 3:187,742,879...187,756,546
|
|
| G
|
Rbm12b
|
RNA binding motif protein 12B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RBM12B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:30,394,756...30,507,428
Ensembl chr 5:30,386,777...30,409,855
|
|
| G
|
Rbm14
|
RNA binding motif protein 14
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RBM14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:211,523,972...211,535,065
|
|
| G
|
Rbm15
|
RNA binding motif protein 15
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RBM15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:197,634,174...197,642,697
Ensembl chr 2:197,583,002...197,643,037
|
|
| G
|
Rbm15b
|
RNA binding motif protein 15B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBM15B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:116,422,309...116,425,374
Ensembl chr 8:116,421,540...116,425,940
|
|
| G
|
Rbm17
|
RNA binding motif protein 17
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBM17 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:71,846,941...71,863,834
Ensembl chr17:71,846,916...71,864,431
|
|
| G
|
Rbm26
|
RNA binding motif protein 26
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RBM26 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:88,299,378...88,379,365
Ensembl chr15:88,301,436...88,378,686
|
|
| G
|
Rbm3
|
RNA binding motif protein 3
|
increases expression
|
EXP
|
coumarin results in increased expression of RBM3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841
|
|
| G
|
Rbm33
|
RNA binding motif protein 33
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RBM33 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:7,714,660...7,825,469
Ensembl chr 4:7,720,180...7,820,882
|
|
| G
|
Rbm39
|
RNA binding motif protein 39
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RBM39 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:165,123,087...165,156,453
Ensembl chr 3:165,123,095...165,149,397
|
|
| G
|
Rbm6
|
RNA binding motif protein 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBM6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:117,327,607...117,431,397
Ensembl chr 8:117,331,325...117,431,397
|
|
| G
|
Rbm7
|
RNA binding motif protein 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RBM7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:57,728,413...57,734,833
Ensembl chr 8:57,728,423...57,734,968
|
|
| G
|
Rbm8a
|
RNA binding motif protein 8A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RBM8A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:186,854,018...186,856,802
Ensembl chr 2:186,854,036...186,856,802
|
|
| G
|
Rbmx
|
RNA binding motif protein, X-linked
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RBMX protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:140,342,544...140,352,121
Ensembl chr X:140,345,571...140,352,035
|
|
| G
|
Rbp1
|
retinol binding protein 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of RBP1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:107,887,417...107,983,847
|
|
| G
|
Rbsn
|
rabenosyn, RAB effector
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RBSN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:126,239,354...126,269,702
Ensembl chr 4:126,239,902...126,266,904
|
|
| G
|
Rc3h1
|
ring finger and CCCH-type domains 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RC3H1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816
|
|
| G
|
Rc3h2
|
ring finger and CCCH-type domains 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RC3H2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:41,531,617...41,589,715
|
|
| G
|
Rcor2
|
REST corepressor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RCOR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,882,585...213,890,022
Ensembl chr 1:213,878,519...213,890,022
|
|
| G
|
Rcor3
|
REST corepressor 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RCOR3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:106,156,166...106,196,542
Ensembl chr13:106,157,232...106,196,575
|
|
| G
|
Recql5
|
RecQ like helicase 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RECQL5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,625,477...101,664,582
Ensembl chr10:101,625,480...101,664,663
|
|
| G
|
Reep3
|
receptor accessory protein 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of REEP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:21,492,695...21,575,138
Ensembl chr20:21,492,721...21,577,521
|
|
| G
|
Relch
|
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RELCH protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:22,321,495...22,417,371
Ensembl chr13:22,321,542...22,417,371
|
|
| G
|
Reps1
|
RALBP1 associated Eps domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of REPS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:14,517,589...14,595,404
Ensembl chr 1:14,517,589...14,595,404
|
|
| G
|
Rere
|
arginine-glutamic acid dipeptide repeats
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RERE protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:166,048,770...166,380,559
Ensembl chr 5:166,048,844...166,380,558
|
|
| G
|
Retreg2
|
reticulophagy regulator family member 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RETREG2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:84,088,935...84,095,072
Ensembl chr 9:84,088,964...84,094,837
|
|
| G
|
Retreg3
|
reticulophagy regulator family member 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RETREG3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:86,529,048...86,552,873
Ensembl chr10:86,529,055...86,552,990
|
|
| G
|
Rexo4
|
REX4 homolog, 3'-5' exonuclease
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of REXO4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:30,678,729...30,692,376
Ensembl chr 3:30,678,740...30,689,059
|
|
| G
|
Rfc1
|
replication factor C subunit 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RFC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:43,319,768...43,395,028
Ensembl chr14:43,319,935...43,395,026
|
|
| G
|
Rfc2
|
replication factor C subunit 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RFC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:27,756,920...27,770,049
Ensembl chr12:27,756,922...27,770,025
|
|
| G
|
RGD1311745
|
similar to RIKEN cDNA 1110059G10
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of KIAA1143 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:131,475,903...131,486,619
Ensembl chr 8:131,475,906...131,482,865
|
|
| G
|
Rgn
|
regucalcin
|
decreases expression
|
EXP
|
coumarin results in decreased expression of RGN mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr X:4,172,537...4,190,112
Ensembl chr X:4,172,537...4,190,251
|
|
| G
|
Rgs8
|
regulator of G-protein signaling 8
|
decreases expression
|
EXP
|
coumarin results in decreased expression of RGS8 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr13:68,355,078...68,399,412
Ensembl chr13:68,355,157...68,399,412
|
|
| G
|
Rhbdf2
|
rhomboid 5 homolog 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RHBDF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:102,331,991...102,359,117
Ensembl chr10:102,331,991...102,359,117
|
|
| G
|
Ric8a
|
RIC8 guanine nucleotide exchange factor A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RIC8A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:205,364,796...205,371,102
Ensembl chr 1:205,363,882...205,371,102
|
|
| G
|
Rif1
|
replication timing regulatory factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RIF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106
|
|
| G
|
Rin1
|
Ras and Rab interactor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RIN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:211,785,107...211,789,755
Ensembl chr 1:211,784,943...211,791,368
|
|
| G
|
Ripk1
|
receptor interacting serine/threonine kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RIPK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167
|
|
| G
|
Ripk2
|
receptor-interacting serine-threonine kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RIPK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663
|
|
| G
|
Rmi1
|
RecQ mediated genome instability 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RMI1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:6,261,961...6,269,947
Ensembl chr17:6,260,896...6,282,052
|
|
| G
|
Rnaseh1
|
ribonuclease H1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RNASEH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:51,011,244...51,020,638
Ensembl chr 6:51,011,234...51,020,627
|
|
| G
|
Rnf146
|
ring finger protein 146
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RNF146 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:30,286,680...30,304,367
Ensembl chr 1:30,287,511...30,304,361
|
|
| G
|
Rnf168
|
ring finger protein 168
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RNF168 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:81,991,352...82,013,306
Ensembl chr11:81,991,360...82,013,306
|
|
| G
|
Rnf20
|
ring finger protein 20
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RNF20 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:68,771,507...68,797,240
Ensembl chr 5:68,771,535...68,797,240
|
|
| G
|
Rnf213
|
ring finger protein 213
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RNF213 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:105,154,873...105,254,148
Ensembl chr10:105,157,904...105,254,148
|
|
| G
|
Rnf214
|
ring finger protein 214
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RNF214 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:55,057,434...55,098,753
Ensembl chr 8:55,060,595...55,099,003
|
|
| G
|
Rnf220
|
ring finger protein 220
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RNF220 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:135,975,739...136,198,017
Ensembl chr 5:135,975,739...136,197,858
|
|
| G
|
Rnf8
|
ring finger protein 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RNF8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:7,683,890...7,708,437
|
|
| G
|
Rnh1
|
ribonuclease/angiogenin inhibitor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RNH1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:205,698,882...205,711,348
Ensembl chr 1:205,698,882...205,711,582
|
|
| G
|
Rock1
|
Rho-associated coiled-coil containing protein kinase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ROCK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147
|
|
| G
|
Rpap1
|
RNA polymerase II associated protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:127,200,450...127,221,985
Ensembl chr 3:127,110,550...127,221,952
|
|
| G
|
Rpgr
|
retinitis pigmentosa GTPase regulator
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPGR protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:15,238,961...15,299,004
Ensembl chr X:15,239,159...15,298,999
|
|
| G
|
Rpl14
|
ribosomal protein L14
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPL14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:129,163,620...129,166,745
Ensembl chr 8:129,163,317...129,167,459
|
|
| G
|
Rpl18a
|
ribosomal protein L18A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPL18A protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:18,576,467...18,578,653
Ensembl chr 1:70,166,729...70,167,654 Ensembl chr16:70,166,729...70,167,654
|
|
| G
|
Rpl19
|
ribosomal protein L19
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPL19 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:83,514,509...83,522,352
Ensembl chr10:83,515,464...83,522,352
|
|
| G
|
Rpl26
|
ribosomal protein L26
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPL26 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:54,109,692...54,112,822
Ensembl chr10:54,109,362...54,112,822
|
|
| G
|
Rpl30
|
ribosomal protein L30
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPL30 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:67,533,420...67,536,555
Ensembl chr 7:67,465,332...67,536,555
|
|
| G
|
Rplp0l1
|
ribosomal protein lateral stalk subunit P0 like 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPLP0P6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:194,609,881...194,611,022
Ensembl chr 2:194,609,950...194,611,022
|
|
| G
|
Rplp2
|
ribosomal protein lateral stalk subunit P2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPLP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191
|
|
| G
|
Rprd1a
|
regulation of nuclear pre-mRNA domain containing 1A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPRD1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:16,066,169...16,114,102
Ensembl chr18:16,066,169...16,114,282
|
|
| G
|
Rprd1b
|
regulation of nuclear pre-mRNA domain containing 1B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPRD1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:167,102,909...167,149,184
Ensembl chr 3:167,102,859...167,206,374
|
|
| G
|
Rprd2
|
regulation of nuclear pre-mRNA domain containing 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RPRD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:186,000,375...186,056,943
Ensembl chr 2:186,000,316...186,056,943
|
|
| G
|
Rprm
|
reprimo, TP53 dependent G2 arrest mediator homolog
|
decreases expression
|
EXP
|
coumarin results in decreased expression of RPRM mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:58,948,618...58,950,035
Ensembl chr 3:58,799,866...58,950,542
|
|
| G
|
Rps27
|
ribosomal protein S27
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPS27 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:177,963,499...177,964,708
Ensembl chr 2:177,963,496...177,964,607 Ensembl chr12:177,963,496...177,964,607
|
|
| G
|
Rps3
|
ribosomal protein S3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPS3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776
|
|
| G
|
Rps3a
|
ribosomal protein S3a
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPS3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
|
|
| G
|
Rps6
|
ribosomal protein S6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPS6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
|
|
| G
|
Rps6ka3
|
ribosomal protein S6 kinase A3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RPS6KA3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:39,325,926...39,432,017
Ensembl chr X:39,325,926...39,433,678
|
|
| G
|
Rps6ka4
|
ribosomal protein S6 kinase A4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPS6KA4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,451,026...213,461,982
Ensembl chr 1:213,451,027...213,461,982
|
|
| G
|
Rps6kb1
|
ribosomal protein S6 kinase B1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPS6KB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
|
|
| G
|
Rps6kb2
|
ribosomal protein S6 kinase B2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPS6KB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:210,880,824...210,887,556
Ensembl chr 1:210,880,825...210,887,562
|
|
| G
|
Rps6kc1
|
ribosomal protein S6 kinase C1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPS6KC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:104,877,296...105,021,490
Ensembl chr13:104,877,296...105,021,435
|
|
| G
|
Rps9
|
ribosomal protein S9
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RPS9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:74,427,084...74,430,513
Ensembl chr 1:74,427,087...74,430,105
|
|
| G
|
Rptor
|
regulatory associated protein of MTOR, complex 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RPTOR protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413
|
|
| G
|
Rreb1
|
ras responsive element binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RREB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:27,082,217...27,208,061
Ensembl chr17:27,082,227...27,208,061
|
|
| G
|
Rrm2
|
ribonucleotide reductase regulatory subunit M2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RRM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
|
|
| G
|
Rrn3
|
RRN3 homolog, RNA polymerase I transcription factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RRN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,637,016...2,672,330
|
|
| G
|
Rrp15
|
ribosomal RNA processing 15 homolog
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RRP15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:100,807,729...100,830,812
Ensembl chr13:100,807,722...100,830,834
|
|
| G
|
Rrp1b
|
ribosomal RNA processing 1B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RRP1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:10,122,825...10,148,404
Ensembl chr20:10,122,812...10,148,404
|
|
| G
|
Rrp7a
|
ribosomal RNA processing 7 homolog A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RRP7A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:116,142,976...116,152,874
Ensembl chr 7:116,136,385...116,152,864
|
|
| G
|
Rrp8
|
ribosomal RNA processing 8
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RRP8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:169,489,829...169,500,551
Ensembl chr 1:169,465,397...169,501,164
|
|
| G
|
Rrp9
|
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RRP9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:115,995,119...116,004,832
Ensembl chr 8:115,996,169...116,004,824
|
|
| G
|
Rsf1
|
remodeling and spacing factor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of RSF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:161,303,596...161,426,326
Ensembl chr 1:161,303,660...161,420,290
|
|
| G
|
Rsl1d1
|
ribosomal L1 domain containing 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of RSL1D1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:4,931,839...4,943,726
Ensembl chr10:4,904,792...4,946,566
|
|
| G
|
RT1-Ba
|
RT1 class II, locus Ba
|
increases expression
|
EXP
|
coumarin results in increased expression of RT1-BA mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653
|
|
| G
|
RT1-DMa
|
RT1 class II, locus DMa
|
increases expression
|
EXP
|
coumarin results in increased expression of HLA-DMA mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335
|
|
| G
|
Rundc3b
|
RUN domain containing 3B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of RUNDC3B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:26,417,501...26,554,404
Ensembl chr 4:26,417,437...26,554,403
|
|
| G
|
Sac3d1
|
SAC3 domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SAC3D1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,843,463...212,845,842
Ensembl chr 1:212,843,463...212,845,883
|
|
| G
|
Sacs
|
sacsin molecular chaperone
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SACS protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:39,461,853...39,546,419
Ensembl chr15:39,472,905...39,546,419
|
|
| G
|
Safb2
|
scaffold attachment factor B2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SAFB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:1,482,985...1,504,142
Ensembl chr 9:1,479,061...1,504,142
|
|
| G
|
Samd4a
|
sterile alpha motif domain containing 4A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SAMD4A protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:22,616,200...22,831,872
Ensembl chr15:22,614,287...22,831,872
|
|
| G
|
Samd4b
|
sterile alpha motif domain containing 4B
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SAMD4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:92,816,955...92,855,243
Ensembl chr 1:92,809,800...92,841,393
|
|
| G
|
Samhd1
|
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SAMHD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:166,179,742...166,214,448
Ensembl chr 3:166,181,588...166,214,410
|
|
| G
|
Sap30bp
|
SAP30 binding protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SAP30BP protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,664,714...101,697,430
Ensembl chr10:101,664,697...101,697,429
|
|
| G
|
Saraf
|
store-operated calcium entry-associated regulatory factor
|
increases expression
|
EXP
|
coumarin results in increased expression of SARAF mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr16:64,720,404...64,738,653
Ensembl chr16:64,720,418...64,738,653
|
|
| G
|
Sart1
|
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SART1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486
|
|
| G
|
Sbf2
|
SET binding factor 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SBF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:173,787,638...174,154,589
Ensembl chr 1:173,788,187...174,154,522
|
|
| G
|
Sbk3
|
SH3 domain binding kinase family, member 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SBK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:77,895,310...77,902,089
Ensembl chr 1:77,896,724...77,900,773
|
|
| G
|
Scaf1
|
SR-related CTD-associated factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SCAF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:104,621,927...104,635,161
Ensembl chr 1:104,621,927...104,635,032
|
|
| G
|
Scaf11
|
SR-related CTD-associated factor 11
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SCAF11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:129,450,872...129,503,280
Ensembl chr 7:129,417,955...129,503,280
|
|
| G
|
Scamp1
|
secretory carrier membrane protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SCAMP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742
|
|
| G
|
Scd
|
stearoyl-CoA desaturase
|
decreases expression
|
EXP
|
coumarin results in decreased expression of SCD1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
|
|
| G
|
Scrib
|
scribble planar cell polarity protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SCRIB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:109,640,034...109,663,354
Ensembl chr 7:109,640,034...109,663,022
|
|
| G
|
Sdcbp
|
syndecan binding protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SDCBP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:24,245,279...24,314,712
Ensembl chr 5:24,245,033...24,326,197
|
|
| G
|
Sdf2l1
|
stromal cell-derived factor 2-like 1
|
increases expression
|
EXP
|
coumarin results in increased expression of SDF2L1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr11:97,376,878...97,379,120
Ensembl chr11:97,376,878...97,379,120
|
|
| G
|
Sec16a
|
SEC16 homolog A, endoplasmic reticulum export factor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SEC16A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:29,627,779...29,662,925
Ensembl chr 3:29,627,779...29,662,319
|
|
| G
|
Sec31a
|
SEC31 homolog A, COPII coat complex component
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SEC31A protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:9,518,655...9,573,579
Ensembl chr14:9,518,648...9,573,585
|
|
| G
|
Sec61a1
|
SEC61 translocon subunit alpha 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SEC61A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:122,530,785...122,545,141
Ensembl chr 4:122,530,789...122,545,141
|
|
| G
|
Secisbp2l
|
SECIS binding protein 2-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SECISBP2L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:133,443,023...133,489,467
Ensembl chr 3:133,445,317...133,489,291
|
|
| G
|
Sel1l
|
SEL1L adaptor subunit of SYVN1 ubiquitin ligase
|
increases expression
|
EXP
|
coumarin results in increased expression of SEL1L mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:116,466,163...116,510,578
|
|
| G
|
Selenbp1
|
selenium binding protein 1
|
affects expression
|
EXP
|
coumarin affects the expression of SELENBP2 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295
|
|
| G
|
Selenos
|
selenoprotein S
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SELENOS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:129,070,230...129,077,991
|
|
| G
|
Sema3f
|
semaphorin 3F
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SEMA3F protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206
|
|
| G
|
Sema6a
|
semaphorin 6A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SEMA6A protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:42,237,227...42,358,540
Ensembl chr18:42,237,228...42,358,540
|
|
| G
|
Sema6d
|
semaphorin 6D
|
increases expression
|
EXP
|
coumarin results in increased expression of SEMA6D mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:132,337,343...132,394,584
|
|
| G
|
Senp1
|
SUMO specific peptidase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SENP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:131,042,237...131,105,826
Ensembl chr 7:131,044,818...131,100,851
|
|
| G
|
Senp6
|
SUMO specific peptidase 6
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SENP6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:89,868,115...89,951,803
Ensembl chr 8:89,868,867...89,948,062
|
|
| G
|
Sephs1
|
selenophosphate synthetase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SEPHS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:78,263,725...78,296,132
Ensembl chr17:78,263,725...78,292,082
|
|
| G
|
Serbp1
|
Serpine1 mRNA binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SERBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:97,731,200...97,748,438
Ensembl chr 4:97,731,277...97,751,518
|
|
| G
|
Serinc1
|
serine incorporator 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SERINC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:37,396,497...37,415,433
Ensembl chr20:37,396,497...37,443,124
|
|
| G
|
Serpina3m
|
serpin family A member 3M
|
affects expression
|
EXP
|
coumarin affects the expression of SERPINA3M mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 6:128,829,569...128,836,844
Ensembl chr 6:128,829,569...128,836,839
|
|
| G
|
Set
|
Set nuclear proto-oncogene
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SET protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:33,732,319...33,743,433
|
|
| G
|
Setd1a
|
SET domain containing 1A, histone lysine methyltransferase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SETD1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,818,752...191,842,167
Ensembl chr 1:191,818,752...191,842,160
|
|
| G
|
Setd2
|
SET domain containing 2, histone lysine methyltransferase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SETD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:119,390,207...119,475,863
|
|
| G
|
Setd5
|
SET domain containing 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SETD5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:147,772,955...147,850,669
Ensembl chr 4:147,773,028...147,850,667
|
|
| G
|
Setdb1
|
SET domain bifurcated histone lysine methyltransferase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SETDB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:185,587,722...185,618,982
|
|
| G
|
Setx
|
senataxin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SETX protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:32,825,771...32,878,740
Ensembl chr 3:32,828,412...32,878,740
|
|
| G
|
Sf3a1
|
splicing factor 3A subunit 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SF3A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:83,254,971...83,275,720
Ensembl chr14:83,254,971...83,275,720
|
|
| G
|
Sf3b1
|
splicing factor 3b, subunit 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SF3B1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:63,986,829...64,026,723
Ensembl chr 9:63,986,829...64,026,719
|
|
| G
|
Sf3b2
|
splicing factor 3b, subunit 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SF3B2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:211,999,777...212,040,686
Ensembl chr 1:211,999,778...212,020,113
|
|
| G
|
Sfmbt1
|
Scm-like with four mbt domains 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SFMBT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:5,896,686...6,016,311
Ensembl chr16:5,897,187...6,011,934
|
|
| G
|
Sfswap
|
splicing factor SWAP
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SFSWAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:32,745,704...32,816,032
Ensembl chr12:32,745,704...32,816,032
|
|
| G
|
Sh2d3a
|
SH2 domain containing 3A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SH2D3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:2,235,359...2,239,578
|
|
| G
|
Sh2d4a
|
SH2 domain containing 4A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SH2D4A protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:26,106,721...26,176,069
Ensembl chr16:26,106,730...26,175,974
|
|
| G
|
Sh3bp4
|
SH3-domain binding protein 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SH3BP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:97,107,877...97,186,878
Ensembl chr 9:97,107,877...97,186,878
|
|
| G
|
Sh3bp5l
|
SH3 binding domain protein 5 like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SH3BP5L protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:43,012,902...43,027,319
Ensembl chr10:43,012,969...43,027,320
|
|
| G
|
Sh3kbp1
|
SH3 domain-containing kinase-binding protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SH3KBP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:38,686,530...39,031,658
Ensembl chr X:38,686,530...39,031,393
|
|
| G
|
Sh3rf1
|
SH3 domain containing ring finger 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SH3RF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:33,746,396...33,912,127
Ensembl chr16:33,746,396...33,912,153
|
|
| G
|
Shc1
|
SHC adaptor protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SHC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914
|
|
| G
|
Shroom1
|
shroom family member 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SHROOM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:38,121,971...38,134,832
Ensembl chr10:38,122,500...38,132,435
|
|
| G
|
Shroom3
|
shroom family member 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SHROOM3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:15,383,769...15,681,158
Ensembl chr14:15,383,769...15,680,462
|
|
| G
|
Shtn1
|
shootin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SHTN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:268,108,095...268,211,947
Ensembl chr 1:268,108,097...268,211,947
|
|
| G
|
Siglec1
|
sialic acid binding Ig like lectin 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SIGLEC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:138,740,171...138,759,966
Ensembl chr 3:138,741,019...138,759,881
|
|
| G
|
Sik1
|
salt-inducible kinase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SIK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698
|
|
| G
|
Sik2
|
salt-inducible kinase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SIK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:60,121,913...60,221,818
|
|
| G
|
Sin3a
|
SIN3 transcription regulator family member A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SIN3A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:66,377,471...66,432,150
Ensembl chr 8:66,381,657...66,434,542
|
|
| G
|
Sin3b
|
SIN3 transcription regulator family member B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SIN3B protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:17,157,352...17,194,051
Ensembl chr16:17,157,352...17,270,664
|
|
| G
|
Sipa1
|
signal-induced proliferation-associated 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SIPA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:212,367,867...212,379,952
Ensembl chr 1:212,367,867...212,377,497
|
|
| G
|
Sipa1l3
|
signal-induced proliferation-associated 1 like 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SIPA1L3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:93,746,187...93,953,606
Ensembl chr 1:93,746,192...93,831,268
|
|
| G
|
Sirt2
|
sirtuin 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SIRT2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499
|
|
| G
|
Six4
|
SIX homeobox 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SIX4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:97,538,202...97,551,872
Ensembl chr 6:97,538,202...97,551,872
|
|
| G
|
Skic2
|
SKI2 subunit of superkiller complex
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SKIC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:3,987,130...3,997,887
Ensembl chr20:3,987,058...3,997,857
|
|
| G
|
Skp1
|
S-phase kinase-associated protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SKP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:36,898,670...36,917,828
Ensembl chr10:36,903,078...36,918,308
|
|
| G
|
Skp2
|
S-phase kinase associated protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SKP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:59,888,413...59,916,438
|
|
| G
|
Slain2
|
SLAIN motif family, member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLAIN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:35,590,050...35,667,734
Ensembl chr14:35,590,057...35,658,684
|
|
| G
|
Slbp
|
stem-loop histone mRNA binding protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLBP protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:81,295,479...81,306,446
Ensembl chr14:81,296,223...81,306,447
|
|
| G
|
Slc16a3
|
solute carrier family 16 member 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC16A3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903
|
|
| G
|
Slc16a7
|
solute carrier family 16 member 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLC16A7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386
|
|
| G
|
Slc17a1
|
solute carrier family 17 member 1
|
increases expression
|
EXP
|
coumarin results in increased expression of SLC17A1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr17:41,647,332...41,683,078
Ensembl chr17:41,649,919...41,681,174
|
|
| G
|
Slc17a3
|
solute carrier family 17 member 3
|
increases expression
|
EXP
|
coumarin results in increased expression of SLC17A3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,698,680...41,723,329
|
|
| G
|
Slc19a1
|
solute carrier family 19 member 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC19A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488
|
|
| G
|
Slc1a2
|
solute carrier family 1 member 2
|
increases expression
|
EXP
|
coumarin results in increased expression of SLC1A2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249
|
|
| G
|
Slc1a3
|
solute carrier family 1 member 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC1A3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:59,482,709...59,557,808
|
|
| G
|
Slc1a5
|
solute carrier family 1 member 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SLC1A5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
|
|
| G
|
Slc20a1
|
solute carrier family 20 member 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC20A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249
|
|
| G
|
Slc20a2
|
solute carrier family 20 member 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC20A2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:76,163,315...76,253,881
Ensembl chr16:76,162,922...76,253,881
|
|
| G
|
Slc25a37
|
solute carrier family 25 member 37
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLC25A37 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:50,944,085...50,986,506
Ensembl chr15:50,946,236...50,986,808
|
|
| G
|
Slc26a2
|
solute carrier family 26 member 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC26A2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:56,918,662...56,937,032
Ensembl chr18:56,923,337...56,937,012
|
|
| G
|
Slc27a2
|
solute carrier family 27 member 2
|
affects expression
|
EXP
|
coumarin affects the expression of SLC27A2 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
|
|
| G
|
Slc28a2
|
solute carrier family 28 member 2
|
decreases expression
|
EXP
|
coumarin results in decreased expression of SLC28A2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:129,778,425...129,841,292
Ensembl chr 3:129,807,537...129,841,291
|
|
| G
|
Slc29a1
|
solute carrier family 29 member 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLC29A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
|
|
| G
|
Slc35b2
|
solute carrier family 35 member B2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC35B2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:22,936,031...22,940,114
Ensembl chr 9:22,935,887...22,939,793
|
|
| G
|
Slc35e3
|
solute carrier family 35, member E3
|
increases expression
|
EXP
|
coumarin results in increased expression of SLC35E3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:55,222,962...55,236,022
Ensembl chr 7:55,219,998...55,236,035
|
|
| G
|
Slc35f2
|
solute carrier family 35, member F2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC35F2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:63,055,503...63,099,791
Ensembl chr 8:63,056,105...63,099,789
|
|
| G
|
Slc35g2
|
solute carrier family 35, member G2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLC35G2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:109,964,589...109,992,347
Ensembl chr 8:109,964,378...109,992,412
|
|
| G
|
Slc39a10
|
solute carrier family 39 member 10
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLC39A10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:62,331,281...62,454,754
Ensembl chr 9:62,370,598...62,454,747
|
|
| G
|
Slc39a14
|
solute carrier family 39 member 14
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SLC39A14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229
|
|
| G
|
Slc39a3
|
solute carrier family 39 member 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC39A3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,327,541...9,333,542
Ensembl chr 7:9,327,455...9,335,845
|
|
| G
|
Slc39a7
|
solute carrier family 39 member 7
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC39A7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:4,824,967...4,828,431
Ensembl chr20:4,824,688...4,828,430
|
|
| G
|
Slc4a1ap
|
solute carrier family 4 member 1 adaptor protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLC4A1AP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:30,625,931...30,653,859
Ensembl chr 6:30,625,931...30,653,792
|
|
| G
|
Slc4a7
|
solute carrier family 4 member 7
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SLC4A7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:13,015,854...13,095,485
Ensembl chr15:13,015,854...13,095,292
|
|
| G
|
Slc6a13
|
solute carrier family 6 member 13
|
decreases expression
|
EXP
|
coumarin results in decreased expression of SLC6A13 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 4:156,211,381...156,248,491
Ensembl chr 4:156,211,462...156,248,489
|
|
| G
|
Slc6a9
|
solute carrier family 6 member 9
|
increases expression
|
EXP
|
coumarin results in increased expression of SLC6A9 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172
|
|
| G
|
Slco4a1
|
solute carrier organic anion transporter family, member 4a1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLCO4A1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:187,936,735...187,955,873
Ensembl chr 3:187,936,820...187,955,871
|
|
| G
|
Slit1
|
slit guidance ligand 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLIT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:250,358,917...250,507,476
Ensembl chr 1:250,358,919...250,507,476
|
|
| G
|
Slk
|
STE20-like kinase
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SLK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829
|
|
| G
|
Sltm
|
SAFB-like, transcription modulator
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SLTM protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:80,096,555...80,142,668
Ensembl chr 8:80,097,652...80,142,671
|
|
| G
|
Smad5
|
SMAD family member 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SMAD5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,871,984...7,890,992
|
|
| G
|
Smarca1
|
SNF2 related chromatin remodeling ATPase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SMARCA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:131,858,148...131,944,639
Ensembl chr X:131,859,088...131,944,282
|
|
| G
|
Smarca4
|
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SMARCA4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:28,443,810...28,535,070
|
|
| G
|
Smarcad1
|
SNF2 related chromatin remodeling ATPase with DExD box 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SMARCAD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:95,639,722...95,709,055
Ensembl chr 4:95,641,295...95,702,414
|
|
| G
|
Smarcc1
|
SWI/SNF related BAF chromatin remodeling complex subunit C1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SMARCC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:118,989,516...119,093,152
|
|
| G
|
Smarcc2
|
SWI/SNF related BAF chromatin remodeling complex subunit C2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SMARCC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:1,466,223...1,494,627
Ensembl chr 7:1,466,454...1,494,626
|
|
| G
|
Smarcd2
|
SWI/SNF related BAF chromatin remodeling complex subunit D2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SMARCD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:91,693,542...91,702,408
Ensembl chr10:91,693,542...91,702,522
|
|
| G
|
Smc1a
|
structural maintenance of chromosomes 1A
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMC1A protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462
|
|
| G
|
Smc3
|
structural maintenance of chromosomes 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:262,606,731...262,649,832
Ensembl chr 1:262,607,080...262,649,825
|
|
| G
|
Smg1
|
SMG1, nonsense mediated mRNA decay associated PI3K related kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMG1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:181,876,134...181,977,894
Ensembl chr 1:181,876,134...181,977,894
|
|
| G
|
Smg6
|
SMG6 nonsense mediated mRNA decay factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SMG6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:60,284,628...60,512,738
Ensembl chr10:60,284,628...60,512,733
|
|
| G
|
Smg9
|
SMG9 nonsense mediated mRNA decay factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMG9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:89,116,459...89,139,182
Ensembl chr 1:89,116,482...89,139,182
|
|
| G
|
Smim13
|
small integral membrane protein 13
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMIM13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:23,703,414...23,721,457
Ensembl chr17:23,703,414...23,721,457
|
|
| G
|
Smndc1
|
survival motor neuron domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMNDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:262,395,034...262,406,104
Ensembl chr 1:262,386,590...262,405,707
|
|
| G
|
Smpdl3b
|
sphingomyelin phosphodiesterase, acid-like 3B
|
increases expression
|
EXP
|
coumarin results in increased expression of SMPDL3B mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:150,228,607...150,250,688
Ensembl chr 5:150,228,611...150,250,688
|
|
| G
|
Smtn
|
smoothelin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SMTN protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:82,622,223...82,644,525
Ensembl chr14:82,621,375...82,644,514
|
|
| G
|
Snai2
|
snail family transcriptional repressor 2
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of SNAI2 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349
|
|
| G
|
Snapc4
|
small nuclear RNA activating complex, polypeptide 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SNAPC4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:29,580,157...29,598,440
Ensembl chr 3:29,580,159...29,597,610
|
|
| G
|
Snd1
|
staphylococcal nuclease and tudor domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SND1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:58,060,640...58,459,925
|
|
| G
|
Snip1
|
Smad nuclear interacting protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SNIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:142,613,028...142,620,502
Ensembl chr 5:142,613,004...142,620,527
|
|
| G
|
Snrnp200
|
small nuclear ribonucleoprotein U5 subunit 200
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SNRNP200 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:134,882,173...134,911,512
Ensembl chr 3:134,882,173...134,911,500
|
|
| G
|
Sntb2
|
syntrophin, beta 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SNTB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:51,739,492...51,832,083
Ensembl chr19:51,741,183...51,823,872
|
|
| G
|
Snupn
|
snurportin 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SNUPN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:66,242,940...66,286,651
Ensembl chr 8:66,235,828...66,286,835
|
|
| G
|
Snx17
|
sorting nexin 17
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SNX17 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:30,897,500...30,902,972
Ensembl chr 6:30,897,501...30,902,972
|
|
| G
|
Snx29
|
sorting nexin 29
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SNX29 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:4,391,866...4,805,682
Ensembl chr10:4,394,544...4,813,772
|
|
| G
|
Snx33
|
sorting nexin 33
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SNX33 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:66,213,133...66,224,926
Ensembl chr 8:66,213,133...66,223,509
|
|
| G
|
Snx9
|
sorting nexin 9
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SNX9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:48,827,061...48,915,215
Ensembl chr 1:48,830,053...48,915,214
|
|
| G
|
Son
|
SON DNA and RNA binding protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SON protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:44,336,818...44,409,127
Ensembl chr11:44,377,976...44,409,127
|
|
| G
|
Sorbs2
|
sorbin and SH3 domain containing 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SORBS2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:53,167,795...53,481,300
Ensembl chr16:53,167,827...53,358,986
|
|
| G
|
Sorbs3
|
sorbin and SH3 domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SORBS3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:51,662,639...51,699,161
Ensembl chr15:51,663,095...51,694,522
|
|
| G
|
Sos1
|
SOS Ras/Rac guanine nucleotide exchange factor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SOS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350
|
|
| G
|
Sox6
|
SRY-box transcription factor 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SOX6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:179,157,678...179,769,243
Ensembl chr 1:179,163,566...179,711,727
|
|
| G
|
Sp1
|
Sp1 transcription factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
|
|
| G
|
Sp100
|
SP100 nuclear antigen
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SP100 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:93,759,075...93,825,068
|
|
| G
|
Sp3
|
Sp3 transcription factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:78,219,421...78,272,318
Ensembl chr 3:78,219,426...78,264,517
|
|
| G
|
Sp4
|
Sp4 transcription factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:145,330,416...145,395,750
Ensembl chr 6:145,330,416...145,395,146
|
|
| G
|
Spag5
|
sperm associated antigen 5
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SPAG5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
|
|
| G
|
Spag9
|
sperm associated antigen 9
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SPAG9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:79,440,311...79,574,709
Ensembl chr10:79,440,377...79,575,258
|
|
| G
|
Spata2
|
spermatogenesis associated 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SPATA2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:176,621,974...176,639,784
Ensembl chr 3:176,622,350...176,632,013
|
|
| G
|
Spc24
|
SPC24 component of NDC80 kinetochore complex
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SPC24 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:28,576,409...28,581,481
Ensembl chr 8:28,576,409...28,581,299
|
|
| G
|
Specc1
|
sperm antigen with calponin homology and coiled-coil domains 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SPECC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:47,138,351...47,412,311
Ensembl chr10:47,138,398...47,412,319
|
|
| G
|
Specc1l
|
sperm antigen with calponin homology and coiled-coil domains 1-like
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SPECC1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:13,337,399...13,443,080
Ensembl chr20:13,339,108...13,443,079
|
|
| G
|
Speg
|
striated muscle enriched protein kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SPEG protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:84,314,387...84,371,816
Ensembl chr 9:84,314,387...84,371,813
|
|
| G
|
Spen
|
spen family transcriptional repressor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SPEN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:159,058,258...159,131,789
Ensembl chr 5:159,058,258...159,165,934
|
|
| G
|
Spindoc
|
spindlin interactor and repressor of chromatin binding
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SPINDOC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,971,995...213,995,162
Ensembl chr 1:213,971,995...213,993,433
|
|
| G
|
Spns1
|
SPNS lysolipid transporter 1, lysophospholipid
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SPNS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:190,372,663...190,380,192
Ensembl chr 1:190,372,666...190,379,943
|
|
| G
|
Sprtn
|
SprT-like N-terminal domain
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SPRTN protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:69,754,989...69,762,240
Ensembl chr19:69,754,980...69,762,237
|
|
| G
|
Spryd3
|
SPRY domain containing 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SPRYD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,126,598...135,143,775
Ensembl chr 7:135,126,598...135,143,974
|
|
| G
|
Sptbn1
|
spectrin, beta, non-erythrocytic 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SPTBN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836
|
|
| G
|
Sqstm1
|
sequestosome 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SQSTM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
|
|
| G
|
Srcap
|
Snf2-related CREBBP activator protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRCAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,554,043...191,607,096
Ensembl chr 1:191,554,043...191,604,265
|
|
| G
|
Srgap1
|
SLIT-ROBO Rho GTPase activating protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SRGAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:59,215,007...59,479,600
Ensembl chr 7:59,215,007...59,656,213
|
|
| G
|
Srp72
|
signal recognition particle 72
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SRP72 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:31,522,424...31,549,978
Ensembl chr14:31,522,963...31,550,151
|
|
| G
|
Srpk2
|
SRSF protein kinase 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRPK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:12,356,983...12,548,345
Ensembl chr 4:12,357,053...12,548,342
|
|
| G
|
Srrm1
|
serine and arginine repetitive matrix 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRRM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:152,843,167...152,875,554
Ensembl chr 5:152,843,169...152,875,436
|
|
| G
|
Srrm2
|
serine/arginine repetitive matrix 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRRM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337
|
|
| G
|
Srrt
|
serrate, RNA effector molecule
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRRT protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:25,027,883...25,042,847
Ensembl chr12:25,029,334...25,042,845
|
|
| G
|
Srsf1
|
serine and arginine rich splicing factor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SRSF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548
|
|
| G
|
Srsf10
|
serine and arginine rich splicing factor 10
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRSF10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:153,372,307...153,386,520
Ensembl chr 5:153,372,316...153,386,513
|
|
| G
|
Srsf11
|
serine and arginine rich splicing factor 11
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SRSF11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499
|
|
| G
|
Srsf4
|
serine and arginine rich splicing factor 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SRSF4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:149,345,538...149,373,309
Ensembl chr 5:149,345,422...149,374,609
|
|
| G
|
Srsf6
|
serine and arginine rich splicing factor 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SRSF6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:172,009,072...172,014,395
Ensembl chr 3:172,009,061...172,014,392
|
|
| G
|
Srsf9
|
serine and arginine rich splicing factor 9
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SRSF9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:46,938,948...46,945,213
Ensembl chr12:46,938,950...46,945,283
|
|
| G
|
Srxn1
|
sulfiredoxin 1
|
increases expression
|
EXP
|
coumarin results in increased expression of SRXN1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
|
|
| G
|
Ssb
|
small RNA binding exonuclease protection factor La
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SSB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:75,024,385...75,034,016
Ensembl chr 3:75,024,474...75,034,031
|
|
| G
|
Ssh2
|
slingshot protein phosphatase 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SSH2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:62,555,388...62,807,457
Ensembl chr10:62,555,460...62,807,453
|
|
| G
|
Stag2
|
STAG2 cohesin complex component
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of STAG2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:125,839,660...125,971,209
Ensembl chr X:125,840,401...125,971,209
|
|
| G
|
Stard3nl
|
STARD3 N-terminal like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STARD3NL protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:50,278,859...50,312,864
Ensembl chr17:50,278,894...50,312,866
|
|
| G
|
Stat1
|
signal transducer and activator of transcription 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STAT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Stat3
|
signal transducer and activator of transcription 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STAT3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
|
|
| G
|
Stat5b
|
signal transducer and activator of transcription 5B
|
increases activity
|
ISO
|
coumarin results in increased activity of STAT5B protein
|
CTD |
PMID:30114225 |
|
NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990
|
|
| G
|
Stim2
|
stromal interaction molecule 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STIM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:61,091,550...61,217,281
Ensembl chr14:61,091,550...61,217,080
|
|
| G
|
Stip1
|
stress-induced phosphoprotein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654
|
|
| G
|
Stk10
|
serine/threonine kinase 10
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of STK10 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:17,622,149...17,716,337
Ensembl chr10:17,622,162...17,716,332
|
|
| G
|
Stk11ip
|
serine/threonine kinase 11 interacting protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STK11IP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:84,459,733...84,476,521
Ensembl chr 9:84,461,336...84,476,915
|
|
| G
|
Stk26
|
serine/threonine kinase 26
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STK26 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:135,195,176...135,259,994
Ensembl chr X:135,195,204...135,259,993
|
|
| G
|
Stk3
|
serine/threonine kinase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:67,938,378...68,208,508
|
|
| G
|
Stk39
|
serine threonine kinase 39
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STK39 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:73,321,522...73,586,740
|
|
| G
|
Strn
|
striatin
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STRN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:22,087,419...22,174,284
Ensembl chr 6:22,087,497...22,193,048
|
|
| G
|
Strn3
|
striatin 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STRN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:74,783,156...74,869,473
Ensembl chr 6:74,783,156...74,869,473
|
|
| G
|
Stx16
|
syntaxin 16
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STX16 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:183,271,417...183,300,746
Ensembl chr 3:183,272,031...183,300,745
|
|
| G
|
Stx6
|
syntaxin 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of STX6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:69,882,647...69,928,895
Ensembl chr13:69,882,620...69,931,036
|
|
| G
|
Stxbp5l
|
syntaxin binding protein 5L
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of STXBP5L protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:76,838,839...77,167,852
Ensembl chr11:76,838,900...77,161,306
|
|
| G
|
Sub1
|
SUB1 regulator of transcription
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SUB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:62,735,379...62,747,545
Ensembl chr 2:62,732,736...62,747,679
|
|
| G
|
Sufu
|
SUFU negative regulator of hedgehog signaling
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUFU protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:255,199,164...255,296,981
|
|
| G
|
Sugp1
|
SURP and G patch domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUGP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:19,386,588...19,417,460
Ensembl chr16:19,386,589...19,417,460
|
|
| G
|
Sult1b1
|
sulfotransferase family 1B member 1
|
affects expression
|
EXP
|
coumarin affects the expression of SULT1B1 mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549
|
|
| G
|
Sult1c3
|
sulfotransferase family 1C member 3
|
decreases expression
|
EXP
|
coumarin results in decreased expression of SULT1C1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295
|
|
| G
|
Sult1e1
|
sulfotransferase family 1E member 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of SULT1E1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716
|
|
| G
|
Sun2
|
Sad1 and UNC84 domain containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:113,155,766...113,172,950
Ensembl chr 7:113,155,766...113,172,940
|
|
| G
|
Sun3
|
Sad1 and UNC84 domain containing 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SUN3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:87,923,891...87,962,699
Ensembl chr14:87,923,074...87,962,867
|
|
| G
|
Supt16h
|
SPT16 homolog, facilitates chromatin remodeling subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUPT16H protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:27,341,196...27,378,314
Ensembl chr15:27,341,196...27,378,314
|
|
| G
|
Supt5h
|
SPT5 homolog, DSIF elongation factor subunit
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SUPT5H protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:92,714,276...92,745,489
Ensembl chr 1:92,714,281...92,744,445
|
|
| G
|
Supt6h
|
SPT6 homolog, histone chaperone and transcription elongation factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUPT6H protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:63,601,990...63,638,851
Ensembl chr10:63,601,993...63,638,851
|
|
| G
|
Surf6
|
surfeit 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SURF6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:30,619,525...30,630,388
Ensembl chr 3:30,619,530...30,630,247
|
|
| G
|
Suv39h1
|
SUV39H1 histone lysine methyltransferase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUV39H1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:17,093,059...17,105,942
Ensembl chr X:17,092,986...17,105,942
|
|
| G
|
Suv39h1-ps1
|
SUV39H1 histone lysine methyltransferase, pseudogene 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUV39H1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:146,828,818...146,831,485
|
|
| G
|
Suv39h2
|
SUV39H2 histone lysine methyltransferase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SUV39H2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:79,665,467...79,684,492
Ensembl chr17:79,665,376...79,684,492
|
|
| G
|
Suz12
|
SUZ12 polycomb repressive complex 2 subunit
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SUZ12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:65,464,948...65,510,846
Ensembl chr10:65,464,969...65,510,846
|
|
| G
|
Svil
|
supervillin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SVIL protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:57,343,910...57,539,508
Ensembl chr17:57,343,910...57,462,660
|
|
| G
|
Syap1
|
synapse associated protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SYAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:35,423,947...35,458,472
Ensembl chr X:35,423,969...35,458,864
|
|
| G
|
Sycp3
|
synaptonemal complex protein 3
|
decreases expression
|
EXP
|
coumarin results in decreased expression of SYCP3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:24,761,476...24,775,933
Ensembl chr 7:24,761,463...24,776,501
|
|
| G
|
Syde1
|
synapse defective Rho GTPase homolog 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SYDE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:11,683,505...11,689,491
Ensembl chr 7:11,681,111...11,690,443
|
|
| G
|
Syne1
|
spectrin repeat containing nuclear envelope protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of SYNE1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:43,917,640...44,388,802
Ensembl chr 1:43,895,994...44,388,721
|
|
| G
|
Syne4
|
spectrin repeat containing nuclear envelope family member 4
|
increases expression
|
EXP
|
coumarin results in increased expression of SYNE4 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:94,696,866...94,701,230
Ensembl chr 1:94,696,609...94,701,230
|
|
| G
|
Synj1
|
synaptojanin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of SYNJ1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:43,678,709...43,755,526
Ensembl chr11:43,678,709...43,755,526
|
|
| G
|
Synpo
|
synaptopodin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SYNPO protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:56,326,369...56,347,359
Ensembl chr18:56,319,571...56,353,306
|
|
| G
|
Synrg
|
synergin, gamma
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of SYNRG protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:69,346,154...69,428,714
Ensembl chr10:69,322,114...69,428,714
|
|
| G
|
Tacc1
|
transforming, acidic coiled-coil containing protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TACC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:73,515,016...73,598,395
Ensembl chr16:73,514,889...73,598,394
|
|
| G
|
Tacc2
|
transforming, acidic coiled-coil containing protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TACC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152
|
|
| G
|
Tacc3
|
transforming, acidic coiled-coil containing protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TACC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:81,275,755...81,289,894
Ensembl chr14:81,275,755...81,289,698
|
|
| G
|
Taf12
|
TATA-box binding protein associated factor 12
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TAF12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:149,756,826...149,772,886
Ensembl chr 5:149,753,105...149,774,315
|
|
| G
|
Taf15
|
TATA-box binding protein associated factor 15
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TAF15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,770,430...68,802,458
|
|
| G
|
Taf1c
|
TATA-box binding protein associated factor, RNA polymerase 1 subunit C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TAF1C protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:64,561,079...64,567,599
Ensembl chr19:64,560,562...64,567,599
|
|
| G
|
Taf9b
|
TATA-box binding protein associated factor 9b
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TAF9B protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:75,354,823...75,366,166
Ensembl chr X:75,354,825...75,366,414
|
|
| G
|
Tanc1
|
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TANC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:64,508,037...64,741,826
Ensembl chr 3:64,508,085...64,741,825
|
|
| G
|
Tanc2
|
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TANC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:91,052,860...91,373,291
Ensembl chr10:91,053,067...91,368,570
|
|
| G
|
Tank
|
TRAF family member-associated NFKB activator
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TANK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:66,522,834...66,598,864
Ensembl chr 3:66,537,175...66,598,864
|
|
| G
|
Taok1
|
TAO kinase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TAOK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,871,198...62,957,595
|
|
| G
|
Taok3
|
TAO kinase 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TAOK3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:44,973,180...45,134,439
Ensembl chr12:44,973,180...45,134,439
|
|
| G
|
Tarbp2
|
Tarbp2 subunit of RISC loading complex
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TARBP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:135,527,710...135,532,826
Ensembl chr 7:135,527,589...135,533,323
|
|
| G
|
Tasor
|
transcription activation suppressor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TASOR protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:2,612,942...2,669,870
Ensembl chr16:2,613,505...2,669,867
|
|
| G
|
Tasor2
|
transcription activation suppressor family member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TASOR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:71,504,656...71,559,878
Ensembl chr17:71,504,822...71,559,035
|
|
| G
|
Tax1bp3
|
Tax1 binding protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TAX1BP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:58,294,357...58,298,875
Ensembl chr10:58,294,073...58,298,875
|
|
| G
|
Tbc1d10b
|
TBC1 domain family, member 10b
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TBC1D10B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:191,245,472...191,257,128
Ensembl chr 1:191,239,615...191,257,128
|
|
| G
|
Tbc1d15
|
TBC1 domain family, member 15
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TBC1D15 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303
|
|
| G
|
Tbc1d17
|
TBC1 domain family, member 17
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TBC1D17 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:104,461,266...104,469,615
Ensembl chr 1:104,461,267...104,469,489
|
|
| G
|
Tbc1d22a
|
TBC1 domain family, member 22a
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TBC1D22A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:119,172,284...119,457,271
Ensembl chr 7:119,172,333...119,457,271
|
|
| G
|
Tbc1d23
|
TBC1 domain family, member 23
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TBC1D23 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:56,772,476...56,830,625
Ensembl chr11:56,772,414...56,830,621
|
|
| G
|
Tbc1d4
|
TBC1 domain family, member 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TBC1D4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:84,670,756...84,848,876
Ensembl chr15:84,670,756...84,848,693
|
|
| G
|
Tbc1d5
|
TBC1 domain family, member 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TBC1D5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:3,740,032...4,256,971
Ensembl chr 9:3,750,325...4,253,581
|
|
| G
|
Tbc1d9b
|
TBC1 domain family member 9B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TBC1D9B protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:34,961,012...34,998,227
Ensembl chr10:34,960,996...34,998,213
|
|
| G
|
Tbx3
|
T-box transcription factor 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TBX3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:42,540,378...42,555,490
Ensembl chr12:42,540,378...42,554,171
|
|
| G
|
Tcea1
|
transcription elongation factor A1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TCEA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156 Ensembl chr 5:12,831,339...12,834,156
|
|
| G
|
Tcf12
|
transcription factor 12
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TCF12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:81,371,201...81,682,337
Ensembl chr 8:81,373,321...81,679,922
|
|
| G
|
Tcf25
|
TCF25 ribosome quality control complex subunit
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TCF25 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:68,323,789...68,358,226
Ensembl chr19:68,323,867...68,358,240
|
|
| G
|
Tcf3
|
transcription factor 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TCF3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,931,251...9,952,994
Ensembl chr 7:9,928,685...9,953,044
|
|
| G
|
Tcof1
|
treacle ribosome biogenesis factor 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TCOF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:56,537,437...56,570,727
Ensembl chr18:56,537,437...56,570,727
|
|
| G
|
Tcp1
|
t-complex 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TCP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527
|
|
| G
|
Tcp11l1
|
t-complex 11 like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TCP11L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:111,478,787...111,547,553
Ensembl chr 3:111,453,221...111,546,454
|
|
| G
|
Tdp1
|
tyrosyl-DNA phosphodiesterase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TDP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:124,892,821...124,960,646
Ensembl chr 6:124,881,574...124,960,642
|
|
| G
|
Tdrd3
|
tudor domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TDRD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:69,748,754...69,911,605
Ensembl chr15:69,749,217...69,884,656
|
|
| G
|
Tead1
|
TEA domain transcription factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TEAD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:176,227,175...176,445,122
Ensembl chr 1:176,227,175...176,438,198
|
|
| G
|
Telo2
|
telomere maintenance 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TELO2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:14,624,998...14,640,235
Ensembl chr10:14,624,998...14,640,211
|
|
| G
|
Tex2
|
testis expressed 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TEX2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:91,936,390...92,046,360
Ensembl chr10:91,936,390...92,045,944
|
|
| G
|
Tfap2a
|
transcription factor AP-2 alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TFAP2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219
|
|
| G
|
Tfap4
|
transcription factor AP-4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TFAP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:11,507,242...11,525,794
Ensembl chr10:11,485,565...11,525,794
|
|
| G
|
Tfdp1
|
transcription factor Dp-1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TFDP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:82,864,220...82,903,166
Ensembl chr16:82,864,226...82,902,996
|
|
| G
|
Tfe3
|
transcription factor binding to IGHM enhancer 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TFE3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:17,401,466...17,414,829
Ensembl chr X:17,401,466...17,414,685
|
|
| G
|
Tfip11
|
tuftelin interacting protein 11
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TFIP11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:49,960,025...49,972,257
Ensembl chr12:49,960,026...49,972,257
|
|
| G
|
Tfpt
|
TCF3 fusion partner
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TFPT protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:74,502,994...74,512,766
Ensembl chr 1:74,502,994...74,513,370
|
|
| G
|
Tfrc
|
transferrin receptor
|
decreases phosphorylation increases expression
|
ISO EXP
|
coumarin results in decreased phosphorylation of TFRC protein coumarin results in increased expression of TFRC mRNA
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
|
|
| G
|
Tgfb1
|
transforming growth factor, beta 1
|
increases expression
|
ISO
|
coumarin analog results in increased expression of TGFB1 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
| G
|
Tgfb1i1
|
transforming growth factor beta 1 induced transcript 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TGFB1I1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:192,258,992...192,265,903
Ensembl chr 1:192,258,598...192,265,903
|
|
| G
|
Tgoln2
|
trans-golgi network protein 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TGOLN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:106,221,503...106,229,360
Ensembl chr 4:106,221,509...106,229,262
|
|
| G
|
Tgs1
|
trimethylguanosine synthase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TGS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:21,322,492...21,356,017
Ensembl chr 5:21,322,492...21,356,017
|
|
| G
|
Thap4
|
THAP domain containing 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of THAP4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:101,689,935...101,729,656
Ensembl chr 9:101,689,936...101,729,441
|
|
| G
|
Thoc1
|
THO complex subunit 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of THOC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:1,253,041...1,291,956
Ensembl chr18:1,256,637...1,292,630
|
|
| G
|
Thoc2
|
THO complex subunit 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of THOC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:125,500,549...125,615,139
Ensembl chr X:125,500,549...125,615,087
|
|
| G
|
Thra
|
thyroid hormone receptor alpha
|
increases expression
|
EXP
|
coumarin results in increased expression of THRA mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
|
|
| G
|
Thrap3
|
thyroid hormone receptor associated protein 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of THRAP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:143,729,821...143,772,105
Ensembl chr 5:143,730,596...143,771,983
|
|
| G
|
Thrsp
|
thyroid hormone responsive
|
affects expression decreases expression
|
EXP
|
coumarin affects the expression of THRSP mRNA coumarin results in decreased expression of THRSP mRNA
|
CTD |
PMID:16963487 PMID:18480146 |
|
NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827
|
|
| G
|
Thumpd3
|
THUMP domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of THUMPD3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:147,741,288...147,764,254
Ensembl chr 4:147,741,309...147,765,579
|
|
| G
|
Ticrr
|
TOPBP1-interacting checkpoint and replication regulator
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TICRR protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:143,006,989...143,048,836
Ensembl chr 1:143,006,924...143,049,133
|
|
| G
|
Tigd2
|
tigger transposable element derived 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TIGD2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:89,744,516...89,747,608
Ensembl chr 4:89,744,510...89,747,940
|
|
| G
|
Timp2
|
TIMP metallopeptidase inhibitor 2
|
increases expression
|
ISO
|
coumarin analog results in increased expression of TIMP2 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
|
|
| G
|
Timp4
|
TIMP metallopeptidase inhibitor 4
|
increases expression
|
ISO
|
coumarin analog results in increased expression of TIMP4 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 4:149,978,667...149,985,350
Ensembl chr 4:149,978,685...149,985,452
|
|
| G
|
Tjp1
|
tight junction protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TJP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
|
|
| G
|
Tjp2
|
tight junction protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TJP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:231,136,243...231,264,750
|
|
| G
|
Tle3
|
TLE family member 3, transcriptional corepressor
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TLE3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:70,753,182...70,799,080
Ensembl chr 8:70,753,383...70,799,074
|
|
| G
|
Tle4
|
TLE family member 4, transcriptional corepressor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TLE4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:221,086,250...221,222,826
Ensembl chr 1:221,086,253...221,222,826
|
|
| G
|
Tlk2
|
tousled-like kinase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TLK2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:90,648,623...90,748,427
Ensembl chr10:90,653,851...90,748,428
|
|
| G
|
Tmed3
|
transmembrane p24 trafficking protein 3
|
increases expression
|
EXP
|
coumarin results in increased expression of TMED3 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 8:99,121,361...99,129,653
Ensembl chr 8:99,121,361...99,129,215
|
|
| G
|
Tmem101
|
transmembrane protein 101
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TMEM101 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:87,605,300...87,609,053
Ensembl chr10:87,605,300...87,608,999
|
|
| G
|
Tmem230
|
transmembrane protein 230
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TMEM230 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:139,925,878...139,950,517
|
|
| G
|
Tmem237
|
transmembrane protein 237
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TMEM237 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:68,027,481...68,066,731
Ensembl chr 9:68,030,664...68,063,525
|
|
| G
|
Tmem245
|
transmembrane protein 245
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TMEM245 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:76,366,157...76,443,108
Ensembl chr 5:76,366,157...76,442,888
|
|
| G
|
Tmem87a
|
transmembrane protein 87A
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TMEM87A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:127,761,490...127,807,314
Ensembl chr 3:127,761,490...127,807,314
|
|
| G
|
Tmem94
|
transmembrane protein 94
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TMEM94 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:101,490,496...101,525,983
Ensembl chr10:101,490,481...101,525,975
|
|
| G
|
Tmpo
|
thymopoietin
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TMPO protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937
|
|
| G
|
Tnf
|
tumor necrosis factor
|
increases expression
|
EXP ISO
|
coumarin results in increased expression of TNF mRNA coumarin analog results in increased expression of TNF protein
|
CTD |
PMID:15135310 PMID:32578917 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tnfrsf9
|
TNF receptor superfamily member 9
|
decreases expression
|
EXP
|
coumarin results in decreased expression of TNFRSF9 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:166,664,494...166,690,831
|
|
| G
|
Tnip2
|
TNFAIP3 interacting protein 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TNIP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:80,452,936...80,470,141
Ensembl chr14:80,452,845...80,470,992
|
|
| G
|
Tnk1
|
tyrosine kinase, non-receptor, 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TNK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:55,070,362...55,084,383
Ensembl chr10:55,069,837...55,078,710
|
|
| G
|
Tnks1bp1
|
tankyrase 1 binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TNKS1BP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:90,542,006...90,566,720
Ensembl chr 3:90,542,033...90,566,713
|
|
| G
|
Tnpo2
|
transportin 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TNPO2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:40,004,271...40,024,565
Ensembl chr19:40,004,275...40,024,187
|
|
| G
|
Tnrc6b
|
trinucleotide repeat containing adaptor 6B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TNRC6B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:114,132,574...114,350,010
Ensembl chr 7:114,132,573...114,342,973
|
|
| G
|
Tns3
|
tensin 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TNS3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:87,387,441...87,619,457
Ensembl chr14:87,387,441...87,619,712
|
|
| G
|
Tom1
|
target of myb1 membrane trafficking protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TOM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:13,411,227...13,446,129
Ensembl chr19:13,411,157...13,446,110
|
|
| G
|
Tom1l1
|
target of myb1 like 1 membrane trafficking protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TOM1L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:75,961,653...76,005,725
Ensembl chr10:75,961,653...76,005,508
|
|
| G
|
Tomm22
|
translocase of outer mitochondrial membrane 22
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TOMM22 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:113,103,863...113,109,056
Ensembl chr 7:113,103,860...113,109,053
|
|
| G
|
Tomm70
|
translocase of outer mitochondrial membrane 70
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TOMM70 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:56,847,837...56,886,302
Ensembl chr11:56,846,334...56,886,320
|
|
| G
|
Top2a
|
DNA topoisomerase II alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TOP2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
|
|
| G
|
Top2b
|
DNA topoisomerase II beta
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TOP2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:11,482,089...11,542,464
Ensembl chr15:11,482,089...11,542,464
|
|
| G
|
Topors
|
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TOPORS protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:60,184,076...60,195,979
Ensembl chr 5:60,182,035...60,194,706
|
|
| G
|
Tor1aip1
|
torsin 1A interacting protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TOR1AIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:70,746,941...70,776,382
Ensembl chr13:70,746,941...70,776,123
|
|
| G
|
Tor1aip2
|
torsin 1A interacting protein 2
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TOR1AIP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:70,775,483...70,806,794
Ensembl chr13:70,780,275...70,806,789 Ensembl chr13:70,780,275...70,806,789
|
|
| G
|
Tp53
|
tumor protein p53
|
increases expression
|
ISO
|
coumarin analog results in increased expression of TP53 mRNA; coumarin analog results in increased expression of TP53 protein
|
CTD |
PMID:32578917 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Tp53bp1
|
tumor protein p53 binding protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TP53BP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
|
|
| G
|
Tp53bp2
|
tumor protein p53 binding protein, 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TP53BP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:96,620,429...96,677,090
Ensembl chr13:96,620,428...96,677,616
|
|
| G
|
Tpd52l1
|
TPD52 like 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TPD52L1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:27,991,131...28,110,158
|
|
| G
|
Tpd52l2
|
TPD52 like 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TPD52L2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,972,321...188,995,721
|
|
| G
|
Tpr
|
translocated promoter region, nuclear basket protein
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TPR protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:64,974,419...65,037,604
Ensembl chr13:64,974,419...65,037,602
|
|
| G
|
Tpx2
|
TPX2, microtubule nucleation factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TPX2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724
|
|
| G
|
Tra2a
|
transformer 2 alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRA2A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:79,551,699...79,570,621
Ensembl chr 4:79,551,542...79,570,619
|
|
| G
|
Tra2b
|
transformer 2 beta
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TRA2B protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:92,293,403...92,311,651
Ensembl chr11:92,293,410...92,311,781
|
|
| G
|
Tradd
|
TNFRSF1A-associated via death domain
|
increases expression
|
ISO
|
coumarin analog results in increased expression of TRADD mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr19:50,046,057...50,048,158
Ensembl chr19:50,046,061...50,052,550
|
|
| G
|
Traf2
|
Tnf receptor-associated factor 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRAF2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691
|
|
| G
|
Trafd1
|
TRAF type zinc finger domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRAFD1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:40,826,251...40,840,169
Ensembl chr12:40,825,851...40,841,320
|
|
| G
|
Tram1
|
translocation associated membrane protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRAM1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:10,425,710...10,450,669
Ensembl chr 5:10,425,633...10,470,056
|
|
| G
|
Trerf1
|
transcriptional regulating factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRERF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:21,131,772...21,355,830
Ensembl chr 9:21,131,777...21,176,016
|
|
| G
|
Trim2
|
tripartite motif-containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRIM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:171,798,654...171,950,193
Ensembl chr 2:171,798,660...171,913,468
|
|
| G
|
Trim24
|
tripartite motif-containing 24
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRIM24 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:67,534,240...67,659,014
Ensembl chr 4:67,534,335...67,684,226
|
|
| G
|
Trim25
|
tripartite motif-containing 25
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRIM25 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:74,310,024...74,328,473
Ensembl chr10:74,310,022...74,331,716
|
|
| G
|
Trim28
|
tripartite motif-containing 28
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TRIM28 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:82,724,838...82,731,572
|
|
| G
|
Trim29
|
tripartite motif-containing 29
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRIM29 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:52,579,175...52,603,919
Ensembl chr 8:52,579,175...52,603,919
|
|
| G
|
Trim36
|
tripartite motif-containing 36
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRIM36 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:41,047,657...41,099,497
Ensembl chr18:41,047,657...41,104,704
|
|
| G
|
Trim56
|
tripartite motif containing 56
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRIM56 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:25,193,224...25,204,032
Ensembl chr12:25,188,167...25,206,855
|
|
| G
|
Trio
|
trio Rho guanine nucleotide exchange factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRIO protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:80,235,485...80,531,824
Ensembl chr 2:80,235,485...80,531,612
|
|
| G
|
Trip12
|
thyroid hormone receptor interactor 12
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRIP12 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:93,364,791...93,491,015
Ensembl chr 9:93,364,791...93,490,159
|
|
| G
|
Trmt1l
|
tRNA methyltransferase 1-like
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRMT1L protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:66,060,186...66,093,247
Ensembl chr13:66,060,162...66,093,643
|
|
| G
|
Trpc2
|
transient receptor potential cation channel subfamily C member 2
|
increases expression
|
EXP
|
coumarin results in increased expression of TRPC2 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:165,871,991...165,885,339
Ensembl chr 1:165,857,557...165,885,055
|
|
| G
|
Trps1
|
transcriptional repressor GATA binding 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRPS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:83,806,121...84,032,609
Ensembl chr 7:83,811,497...84,031,786
|
|
| G
|
Trpt1
|
tRNA phosphotransferase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRPT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:213,615,503...213,620,502
Ensembl chr 1:213,614,135...213,620,502
|
|
| G
|
Trrap
|
transformation/transcription domain-associated protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TRRAP protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:14,851,758...14,941,444
Ensembl chr12:14,851,758...14,941,407
|
|
| G
|
Trub1
|
TruB pseudouridine synthase family member 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TRUB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:266,518,510...266,559,633
Ensembl chr 1:266,520,637...266,581,178
|
|
| G
|
Tsc22d1
|
TSC22 domain family, member 1
|
decreases expression
|
EXP
|
coumarin results in decreased expression of TSC22D1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
|
|
| G
|
Tsc22d2
|
TSC22 domain family, member 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TSC22D2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:144,796,760...144,847,930
Ensembl chr 2:144,796,841...144,843,559
|
|
| G
|
Tsc22d4
|
TSC22 domain family, member 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TSC22D4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:24,575,948...24,588,806
Ensembl chr12:24,567,176...24,587,894
|
|
| G
|
Tshz2
|
teashirt zinc finger homeobox 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of TSHZ2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:178,824,221...179,271,151
Ensembl chr 3:178,824,994...179,269,641
|
|
| G
|
Tst
|
thiosulfate sulfurtransferase
|
affects expression
|
EXP
|
coumarin affects the expression of TST mRNA
|
CTD |
PMID:16963487 |
|
NCBI chr 7:111,828,557...111,836,980
Ensembl chr 7:111,828,558...111,837,116
|
|
| G
|
Ttc1
|
tetratricopeptide repeat domain 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TTC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:28,703,763...28,728,910
Ensembl chr10:28,703,769...28,728,882
|
|
| G
|
Ttc28
|
tetratricopeptide repeat domain 28
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of TTC28 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:51,002,816...51,443,461
Ensembl chr12:51,005,089...51,443,531
|
|
| G
|
Ttc39a
|
tetratricopeptide repeat domain 39A
|
increases expression
|
EXP
|
coumarin results in increased expression of TTC39A mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:129,379,560...129,441,779
Ensembl chr 5:129,380,753...129,433,372
|
|
| G
|
Ttf1
|
transcription termination factor 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TTF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:32,782,544...32,807,202
Ensembl chr 3:32,782,308...32,807,201
|
|
| G
|
Ttk
|
Ttk protein kinase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TTK protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
|
|
| G
|
Ttn
|
titin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TTN protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171
|
|
| G
|
Tuba1b
|
tubulin, alpha 1B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TUBA1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:131,969,606...131,972,587
Ensembl chr 7:131,968,770...131,996,035
|
|
| G
|
Tubb5
|
tubulin, beta 5 class I
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TUBB protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726
|
|
| G
|
Txlna
|
taxilin alpha
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TXLNA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:147,253,694...147,269,410
Ensembl chr 5:147,255,649...147,269,273
|
|
| G
|
Txlng
|
taxilin gamma
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TXLNG protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:35,495,822...35,544,716
Ensembl chr X:35,495,893...35,544,716
|
|
| G
|
Txnip
|
thioredoxin interacting protein
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of TXNIP protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
|
|
| G
|
Txnrd1
|
thioredoxin reductase 1
|
increases expression
|
EXP
|
coumarin results in increased expression of TXNRD1 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
|
|
| G
|
Uba1
|
ubiquitin-like modifier activating enzyme 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UBA1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:4,062,216...4,084,192
Ensembl chr X:4,062,182...4,084,246
|
|
| G
|
Ubap2l
|
ubiquitin associated protein 2-like
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of UBAP2L protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:177,736,378...177,791,746
Ensembl chr 2:177,736,696...177,791,646
|
|
| G
|
Ube2j1
|
ubiquitin-conjugating enzyme E2, J1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UBE2J1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:52,218,807...52,237,805
Ensembl chr 5:52,218,807...52,237,805
|
|
| G
|
Ube2o
|
ubiquitin-conjugating enzyme E2O
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of UBE2O protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:102,264,418...102,311,578
Ensembl chr10:102,264,418...102,311,549
|
|
| G
|
Ube4b
|
ubiquitination factor E4B
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UBE4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:165,049,897...165,153,572
Ensembl chr 5:165,049,897...165,153,572
|
|
| G
|
Ubl7
|
ubiquitin-like 7
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UBL7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:67,217,151...67,236,224
Ensembl chr 8:67,216,527...67,236,224
|
|
| G
|
Ubr2
|
ubiquitin protein ligase E3 component n-recognin 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UBR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:21,480,058...21,559,936
Ensembl chr 9:21,480,037...21,559,936
|
|
| G
|
Ubr4
|
ubiquitin protein ligase E3 component n-recognin 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of UBR4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:156,919,029...157,027,127
Ensembl chr 5:156,919,085...157,027,127
|
|
| G
|
Ubr5
|
ubiquitin protein ligase E3 component n-recognin 5
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of UBR5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:71,000,197...71,109,813
|
|
| G
|
Ubtf
|
upstream binding transcription factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of UBTF protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:87,758,346...87,775,377
Ensembl chr10:87,758,346...87,773,088
|
|
| G
|
Ubxn7
|
UBX domain protein 7
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of UBXN7 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:81,932,944...81,965,142 NCBI chr11:81,903,235...81,920,998
Ensembl chr11:81,903,996...81,965,142
|
|
| G
|
Ugdh
|
UDP-glucose 6-dehydrogenase
|
increases expression
|
EXP
|
coumarin results in increased expression of UGDH mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629
|
|
| G
|
Uggt2
|
UDP-glucose glycoprotein glucosyltransferase 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UGGT2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:102,480,239...102,646,291
Ensembl chr15:102,480,781...102,646,410
|
|
| G
|
Ugt2b
|
UDP glycosyltransferase 2 family, polypeptide B
|
decreases expression
|
EXP
|
coumarin results in decreased expression of UGT2B mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr14:20,985,449...21,006,267
Ensembl chr14:20,985,108...21,020,850
|
|
| G
|
Uimc1
|
ubiquitin interaction motif containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UIMC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:9,528,923...9,597,967
Ensembl chr17:9,528,950...9,597,963
|
|
| G
|
Ulk1
|
unc-51 like autophagy activating kinase 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ULK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746
|
|
| G
|
Upf1
|
UPF1, RNA helicase and ATPase
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of UPF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:19,110,531...19,131,327
Ensembl chr16:19,110,538...19,131,327
|
|
| G
|
Upf3b
|
UPF3B, regulator of nonsense mediated mRNA decay
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of UPF3B protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:121,200,993...121,219,059
Ensembl chr X:121,200,993...121,218,921
|
|
| G
|
Uri1
|
URI1, prefoldin-like chaperone
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of URI1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:99,783,158...99,853,906
|
|
| G
|
Urod
|
uroporphyrinogen decarboxylase
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UROD protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:135,701,294...135,705,380
Ensembl chr 5:135,701,296...135,705,380
|
|
| G
|
Uso1
|
USO1 vesicle transport factor
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of USO1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:16,150,921...16,216,389
Ensembl chr14:16,150,923...16,216,389
|
|
| G
|
Usp1
|
ubiquitin specific peptidase 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of USP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:118,703,056...118,714,426
Ensembl chr 5:118,702,868...118,714,434
|
|
| G
|
Usp16
|
ubiquitin specific peptidase 16
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of USP16 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:40,166,651...40,196,792
Ensembl chr11:40,167,692...40,196,823
|
|
| G
|
Usp20
|
ubiquitin specific peptidase 20
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of USP20 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:34,670,613...34,704,156
Ensembl chr 3:34,670,685...34,704,156
|
|
| G
|
Usp32
|
ubiquitin specific peptidase 32
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of USP32 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:70,353,310...70,538,008
Ensembl chr10:70,353,310...70,538,324
|
|
| G
|
Usp34
|
ubiquitin specific peptidase 34
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of USP34 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:101,487,110...101,677,519
Ensembl chr14:101,487,153...101,678,632
|
|
| G
|
Usp36
|
ubiquitin specific peptidase 36
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of USP36 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,995,970...104,023,450
|
|
| G
|
Usp37
|
ubiquitin specific peptidase 37
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of USP37 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:83,467,966...83,567,848
Ensembl chr 9:83,467,966...83,533,172
|
|
| G
|
Usp42
|
ubiquitin specific peptidase 42
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of USP42 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:15,903,110...15,954,429
Ensembl chr12:15,931,703...15,953,711
|
|
| G
|
Usp47
|
ubiquitin specific peptidase 47
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of USP47 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:175,586,723...175,669,904
|
|
| G
|
Usp8
|
ubiquitin specific peptidase 8
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of USP8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:134,413,832...134,463,040
Ensembl chr 3:134,415,391...134,463,032
|
|
| G
|
Ust5r
|
integral membrane transport protein UST5r
|
decreases expression
|
EXP
|
coumarin results in decreased expression of UST5R mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:214,640,172...214,716,024
Ensembl chr 1:214,640,172...214,715,861
|
|
| G
|
Utp14a
|
UTP14A small subunit processome component
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of UTP14A protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:132,317,163...132,342,524
Ensembl chr X:132,317,159...132,342,523
|
|
| G
|
Utp18
|
UTP18 small subunit processome component
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of UTP18 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:79,308,785...79,336,241
Ensembl chr10:79,308,787...79,336,197
|
|
| G
|
Vamp1
|
vesicle-associated membrane protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VAMP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:159,698,894...159,705,582
Ensembl chr 4:159,698,629...159,713,608
|
|
| G
|
Vamp3
|
vesicle-associated membrane protein 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of VAMP3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:166,780,927...166,791,522
Ensembl chr 5:166,780,929...166,791,549
|
|
| G
|
Vangl1
|
VANGL planar cell polarity protein 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VANGL1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:192,277,762...192,326,151
Ensembl chr 2:192,280,422...192,326,186
|
|
| G
|
Vapa
|
VAMP associated protein A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of VAPA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:112,624,791...112,654,731
Ensembl chr 9:112,624,794...112,654,731
|
|
| G
|
Vapb
|
VAMP associated protein B and C
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VAPB protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:182,954,247...182,997,018
Ensembl chr 3:182,954,240...183,028,619
|
|
| G
|
Vat1
|
vesicle amine transport 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VAT1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:86,889,793...86,897,411
Ensembl chr10:86,889,793...86,897,411
|
|
| G
|
Vax2
|
ventral anterior homeobox 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VAX2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:117,753,180...117,777,242
Ensembl chr 4:117,753,180...117,777,242
|
|
| G
|
Vcl
|
vinculin
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VCL protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,315,069...3,405,163
|
|
| G
|
Vcpip1
|
valosin containing protein interacting protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VCPIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:14,317,083...14,343,724
Ensembl chr 5:14,316,918...14,347,778
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
ISO
|
coumarin analog results in increased expression of VEGFA mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
| G
|
Vezt
|
vezatin, adherens junctions transmembrane protein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VEZT protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:30,399,208...30,484,429
Ensembl chr 7:30,421,243...30,484,347
|
|
| G
|
Vgll4
|
vestigial-like family member 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VGLL4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:149,598,151...149,711,186
Ensembl chr 4:149,598,891...149,660,594
|
|
| G
|
Vim
|
vimentin
|
decreases expression affects phosphorylation
|
ISO
|
coumarin analog results in decreased expression of VIM protein coumarin affects the phosphorylation of VIM protein
|
CTD |
PMID:32578917 PMID:35688186 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
|
|
| G
|
Virma
|
vir like m6A methyltransferase associated
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VIRMA protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:29,758,529...29,822,030
Ensembl chr 5:29,758,147...29,822,156
|
|
| G
|
Vkorc1
|
vitamin K epoxide reductase complex, subunit 1
|
decreases response to substance increases response to substance
|
ISO
|
VKORC1 gene mutant form results in decreased susceptibility to coumarin VKORC1 gene mutant form results in increased susceptibility to coumarin; VKORC1 promoter SNP results in increased susceptibility to coumarin
|
CTD |
PMID:17849045 PMID:18278162 |
|
NCBI chr 1:191,932,969...191,935,490
|
|
| G
|
Vps26b
|
VPS26 retromer complex component B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VPS26B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:33,675,025...33,696,132
Ensembl chr 8:33,675,025...33,696,132
|
|
| G
|
Vps4b
|
vacuolar protein sorting 4 homolog B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VPS4B protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:23,421,758...23,446,848
Ensembl chr13:23,421,758...23,446,973
|
|
| G
|
Vps50
|
VPS50 subunit of EARP/GARPII complex
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of VPS50 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:32,439,101...32,540,299
Ensembl chr 4:32,439,138...32,540,538
|
|
| G
|
Vti1b
|
vesicle transport through interaction with t-SNAREs 1B
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of VTI1B protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:103,694,342...103,709,544
Ensembl chr 6:103,694,345...103,709,295
|
|
| G
|
Wac
|
WW domain containing adaptor with coiled-coil
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of WAC protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:60,617,702...60,677,771
Ensembl chr17:60,617,544...60,679,267
|
|
| G
|
Wapl
|
WAPL cohesin release factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WAPL protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:10,011,741...10,081,472
Ensembl chr16:10,012,110...10,081,472
|
|
| G
|
Wbp11
|
WW domain binding protein 11
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of WBP11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:171,412,187...171,425,634
Ensembl chr 4:171,412,189...171,425,634
|
|
| G
|
Wdr13
|
WD repeat domain 13
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WDR13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:17,034,779...17,045,682
Ensembl chr X:17,034,504...17,045,679
|
|
| G
|
Wdr3
|
WD repeat domain 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of WDR3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:190,194,474...190,217,087
Ensembl chr 2:190,194,474...190,217,087
|
|
| G
|
Wdr43
|
WD repeat domain 43
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of WDR43 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:29,565,610...29,604,954
Ensembl chr 6:29,565,610...29,604,954
|
|
| G
|
Wdr44
|
WD repeat domain 44
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WDR44 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:119,286,802...119,392,240
Ensembl chr X:119,287,142...119,392,232
|
|
| G
|
Wdr62
|
WD repeat domain 62
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of WDR62 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:94,618,992...94,658,097
Ensembl chr 1:94,618,992...94,658,223
|
|
| G
|
Wdr81
|
WD repeat domain 81
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WDR81 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:60,780,268...60,793,671
Ensembl chr10:60,780,268...60,793,592
|
|
| G
|
Wee1
|
WEE1 G2 checkpoint kinase
|
increases expression decreases phosphorylation
|
EXP ISO
|
coumarin results in increased expression of WEE1 mRNA coumarin results in decreased phosphorylation of WEE1 protein
|
CTD |
PMID:18480146 PMID:35688186 |
|
NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449
|
|
| G
|
Wfs1
|
wolframin ER transmembrane glycoprotein
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WFS1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:78,035,205...78,059,718
Ensembl chr14:78,034,864...78,060,459
|
|
| G
|
Wiz
|
WIZ zinc finger
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of WIZ protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:12,017,374...12,045,812
Ensembl chr 7:12,017,374...12,045,787
|
|
| G
|
Wnk1
|
WNK lysine deficient protein kinase 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of WNK1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:154,800,590...154,926,147
|
|
| G
|
Wrap53
|
WD repeat containing, antisense to TP53
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of WRAP53 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,773,282...54,797,651
|
|
| G
|
Wrnip1
|
WRN helicase interacting protein 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of WRNIP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr17:31,830,159...31,850,408
Ensembl chr17:31,830,160...31,850,408
|
|
| G
|
Wwc1
|
WW and C2 domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WWC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:20,804,173...20,958,437
Ensembl chr10:20,799,237...20,958,437
|
|
| G
|
Wwc2
|
WW and C2 domain containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of WWC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr16:50,991,096...51,154,529
Ensembl chr16:50,991,096...51,154,526
|
|
| G
|
Wwc3
|
WWC family member 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of WWC3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:27,146,018...27,263,446
Ensembl chr X:27,145,812...27,263,446
|
|
| G
|
Wwp2
|
WW domain containing E3 ubiquitin protein ligase 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of WWP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:52,256,563...52,380,967
Ensembl chr19:52,256,551...52,382,415
|
|
| G
|
Xirp2
|
xin actin-binding repeat containing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of XIRP2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:72,534,175...72,621,056
Ensembl chr 3:72,534,146...72,621,056
|
|
| G
|
Xpc
|
XPC complex subunit, DNA damage recognition and repair factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of XPC protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305
|
|
| G
|
Xpo1
|
exportin 1
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of XPO1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:101,434,450...101,476,705
Ensembl chr14:101,434,517...101,476,714
|
|
| G
|
Xpo4
|
exportin 4
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of XPO4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:35,832,567...35,923,262
Ensembl chr15:35,832,567...35,923,670
|
|
| G
|
Xpr1
|
xenotropic and polytropic retrovirus receptor 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of XPR1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:69,991,517...70,136,249
Ensembl chr13:69,996,692...70,136,164
|
|
| G
|
Xrcc1
|
X-ray repair cross complementing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of XRCC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613
|
|
| G
|
Xrcc2
|
X-ray repair cross complementing 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of XRCC2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:10,157,130...10,237,089
Ensembl chr 4:10,157,800...10,176,407
|
|
| G
|
Xrcc4
|
X-ray repair cross complementing 4
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of XRCC4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:22,686,508...22,933,160
|
|
| G
|
Xrcc6
|
X-ray repair cross complementing 6
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of XRCC6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:115,423,026...115,443,884
Ensembl chr 7:115,422,662...115,443,884
|
|
| G
|
Xrn1
|
5'-3' exoribonuclease 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of XRN1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:105,407,785...105,516,967
Ensembl chr 8:105,407,785...105,512,321
|
|
| G
|
Xrn2
|
5'-3' exoribonuclease 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of XRN2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:154,888,558...154,962,519
Ensembl chr 3:154,890,061...154,962,486
|
|
| G
|
Yap1
|
Yes1 associated transcriptional regulator
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of YAP1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437
|
|
| G
|
Ybx1
|
Y box binding protein 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of YBX1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:138,167,444...138,188,155
Ensembl chr 5:138,167,444...138,184,188
|
|
| G
|
Ybx3
|
Y box binding protein 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of YBX3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691
|
|
| G
|
Yju2
|
YJU2 splicing factor
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of YJU2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:876,790...886,687
Ensembl chr 9:876,822...889,987
|
|
| G
|
Yrdc
|
yrdC N(6)-threonylcarbamoyltransferase domain containing
|
increases expression
|
EXP
|
coumarin results in increased expression of YRDC mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 5:142,394,833...142,399,798
Ensembl chr 5:142,394,938...142,399,795
|
|
| G
|
Ythdc1
|
YTH N6-methyladenosine RNA binding protein C1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of YTHDC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr14:21,540,276...21,570,724
Ensembl chr14:21,540,278...21,570,769
|
|
| G
|
Ythdf1
|
YTH N6-methyladenosine RNA binding protein F1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of YTHDF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:188,402,228...188,417,740
Ensembl chr 3:188,402,231...188,417,740
|
|
| G
|
Zbtb1
|
zinc finger and BTB domain containing 1
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZBTB1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:100,838,714...100,852,643
|
|
| G
|
Zbtb11
|
zinc finger and BTB domain containing 11
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZBTB11 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:58,061,355...58,121,768
Ensembl chr11:58,085,351...58,120,110
|
|
| G
|
Zbtb17
|
zinc finger and BTB domain containing 17
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZBTB17 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:159,036,482...159,057,580
Ensembl chr 5:159,036,515...159,057,581
|
|
| G
|
Zbtb21
|
zinc finger and BTB domain containing 21
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZBTB21 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:50,781,697...50,796,399
Ensembl chr11:50,781,099...50,796,560
|
|
| G
|
Zbtb3
|
zinc finger and BTB domain containing 3
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZBTB3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:215,125,200...215,127,517
Ensembl chr 1:215,112,991...215,139,026
|
|
| G
|
Zbtb33
|
zinc finger and BTB domain containing 33
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZBTB33 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:121,828,960...121,836,193
Ensembl chr X:121,828,952...121,839,399
|
|
| G
|
Zbtb7a
|
zinc finger and BTB domain containing 7a
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZBTB7A protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:9,211,733...9,229,273
Ensembl chr 7:9,214,496...9,227,252
|
|
| G
|
Zbtb9
|
zinc finger and BTB domain containing 9
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZBTB9 protein
|
CTD |
PMID:35688186 |
|
NCBI chr20:5,059,296...5,069,422
Ensembl chr20:5,059,297...5,067,144
|
|
| G
|
Zc3h11a
|
zinc finger CCCH-type containing 11A
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZC3H11A protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:47,625,444...47,665,971
|
|
| G
|
Zc3h13
|
zinc finger CCCH type containing 13
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZC3H13 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:57,016,686...57,081,201
Ensembl chr15:57,016,781...57,081,201
|
|
| G
|
Zc3h14
|
zinc finger CCCH type containing 14
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZC3H14 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 6:123,736,120...123,773,775
Ensembl chr 6:123,736,148...123,774,266
|
|
| G
|
Zc3h18
|
zinc finger CCCH-type containing 18
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZC3H18 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:67,344,422...67,388,400
Ensembl chr19:67,343,434...67,388,399
|
|
| G
|
Zc3h4
|
zinc finger CCCH-type containing 4
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZC3H4 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:86,234,457...86,271,963
Ensembl chr 1:86,234,457...86,271,963
|
|
| G
|
Zc3hav1
|
zinc finger CCCH-type containing, antiviral 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZC3HAV1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:67,979,055...68,029,353
Ensembl chr 4:67,979,055...68,029,353
|
|
| G
|
Zc3hc1
|
zinc finger, C3HC-type containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZC3HC1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:59,957,402...59,979,336
Ensembl chr 4:59,957,402...59,979,336
|
|
| G
|
Zdhhc20
|
zinc finger DHHC-type palmitoyltransferase 20
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZDHHC20 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:36,095,624...36,154,546
Ensembl chr15:36,098,282...36,154,532
|
|
| G
|
Zdhhc5
|
zinc finger DHHC-type palmitoyltransferase 5
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZDHHC5 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:90,179,516...90,201,881
|
|
| G
|
Zeb1
|
zinc finger E-box binding homeobox 1
|
decreases expression
|
ISO
|
coumarin analog results in decreased expression of ZEB1 mRNA
|
CTD |
PMID:32578917 |
|
NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745
|
|
| G
|
Zfc3h1
|
zinc finger, C3H1-type containing
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZFC3H1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 7:52,894,417...52,950,755
Ensembl chr 7:52,894,172...52,950,758
|
|
| G
|
Zfhx3
|
zinc finger homeobox 3
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZFHX3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:52,789,146...53,795,664
Ensembl chr19:53,551,488...53,795,664
|
|
| G
|
Zfp106
|
zinc finger protein 106
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZNF106 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:127,912,981...127,964,254
Ensembl chr 3:127,912,981...127,964,254
|
|
| G
|
Zfp112
|
zinc finger protein 112
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZNF112 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:88,804,833...88,819,889
Ensembl chr 1:88,813,821...88,819,761
|
|
| G
|
Zfp148
|
zinc finger protein 148
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZNF148 protein
|
CTD |
PMID:35688186 |
|
NCBI chr11:80,780,865...80,890,877
Ensembl chr11:80,786,087...80,890,877
|
|
| G
|
Zfp185
|
zinc finger protein 185
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZNF185 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:155,874,138...155,919,921
Ensembl chr X:155,874,127...155,917,077
|
|
| G
|
Zfp217
|
zinc finger protein 217
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNF217 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:179,309,178...179,349,853
Ensembl chr 3:179,310,973...179,321,892
|
|
| G
|
Zfp276
|
zinc finger protein (C2H2 type) 276
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZNF276 protein
|
CTD |
PMID:35688186 |
|
NCBI chr19:68,199,709...68,212,757
Ensembl chr19:68,199,265...68,212,757
|
|
| G
|
Zfp316
|
zinc finger protein 316
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZNF316 protein
|
CTD |
PMID:35688186 |
|
NCBI chr12:16,408,032...16,427,427
Ensembl chr12:16,408,464...16,427,427
|
|
| G
|
Zfp318
|
zinc finger protein 318
|
affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZNF318 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 9:22,060,899...22,100,174
Ensembl chr 9:22,060,916...22,099,551
|
|
| G
|
Zfp362
|
zinc finger protein 362
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNF362 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 5:146,403,469...146,437,707
Ensembl chr 5:146,404,294...146,437,163
|
|
| G
|
Zfp407
|
zinc finger protein 407
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZNF407 protein
|
CTD |
PMID:35688186 |
|
NCBI chr18:79,846,012...80,245,177
Ensembl chr18:79,846,012...80,245,106
|
|
| G
|
Zfp444
|
zinc finger protein 444
|
increases expression
|
EXP
|
coumarin results in increased expression of ZFP444 mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr 1:76,741,399...76,762,388
Ensembl chr 1:76,744,237...76,761,450
|
|
| G
|
Zfp446
|
zinc finger protein 446
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNF446 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:82,673,920...82,680,414
Ensembl chr 1:82,673,918...82,685,430
|
|
| G
|
Zfp511
|
zinc finger protein 511
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZNF511 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:204,247,349...204,251,754
Ensembl chr 1:204,247,230...204,251,754
|
|
| G
|
Zfp560
|
zinc finger protein 560
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZNF121 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:27,176,392...27,190,689
Ensembl chr 8:27,176,778...27,190,608
|
|
| G
|
Zfp566
|
zinc finger protein 566
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNF566 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:94,445,850...94,461,215
Ensembl chr 1:94,446,515...94,460,665
|
|
| G
|
Zfp579
|
zinc finger protein 579
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNF579 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:77,876,367...77,879,591
Ensembl chr 1:77,875,814...77,879,783
|
|
| G
|
Zfp592
|
zinc finger protein 592
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNF592 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 1:144,355,227...144,411,686
Ensembl chr 1:144,361,654...144,411,684
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| G
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Zfp593
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zinc finger protein 593
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increases expression
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EXP
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coumarin results in increased expression of ZNF593 mRNA
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CTD |
PMID:18480146 |
|
NCBI chr 5:151,746,396...151,748,724
Ensembl chr 5:151,746,396...151,748,891
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| G
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Zfp609
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zinc finger protein 609
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increases phosphorylation
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ISO
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coumarin results in increased phosphorylation of ZNF609 protein
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CTD |
PMID:35688186 |
|
NCBI chr 8:75,109,676...75,243,045
Ensembl chr 8:75,109,676...75,213,086
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| G
|
Zfp638
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zinc finger protein 638
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affects phosphorylation
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ISO
|
coumarin affects the phosphorylation of ZNF638 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:117,913,528...118,032,644
Ensembl chr 4:117,913,545...118,032,643
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| G
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Zfp644
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zinc finger protein 644
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decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ZNF644 protein
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CTD |
PMID:35688186 |
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NCBI chr14:3,248,350...3,324,820
Ensembl chr14:3,249,888...3,324,820
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| G
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Zfp687
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zinc finger protein 687
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affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZNF687 protein
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CTD |
PMID:35688186 |
|
NCBI chr 2:185,261,903...185,270,651
Ensembl chr 2:185,261,903...185,270,641
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| G
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Zfp692
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zinc finger protein 692
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decreases phosphorylation
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ISO
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coumarin results in decreased phosphorylation of ZNF692 protein
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CTD |
PMID:35688186 |
|
NCBI chr10:42,988,946...42,997,009
Ensembl chr10:42,988,938...42,997,015
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| G
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Zfp768
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zinc finger protein 768
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increases phosphorylation
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ISO
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coumarin results in increased phosphorylation of ZNF768 protein
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CTD |
PMID:35688186 |
|
NCBI chr 1:191,396,807...191,401,880
Ensembl chr 1:191,396,809...191,399,640
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| G
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Zfyve16
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zinc finger FYVE-type containing 16
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decreases phosphorylation
|
ISO
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coumarin results in decreased phosphorylation of ZFYVE16 protein
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CTD |
PMID:35688186 |
|
NCBI chr 2:25,448,264...25,495,180
Ensembl chr 2:25,448,829...25,483,295
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| G
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Zfyve26
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zinc finger FYVE-type containing 26
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increases phosphorylation
|
ISO
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coumarin results in increased phosphorylation of ZFYVE26 protein
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CTD |
PMID:35688186 |
|
NCBI chr 6:103,764,864...103,828,520
Ensembl chr 6:103,765,510...103,828,463
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| G
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Zhx1
|
zinc fingers and homeoboxes 1
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increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZHX1 protein
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CTD |
PMID:35688186 |
|
NCBI chr 7:91,472,193...91,501,984
Ensembl chr 7:91,473,836...91,501,115
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| G
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Zkscan8
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zinc finger with KRAB and SCAN domains 8
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increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZKSCAN8 protein
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CTD |
PMID:35688186 |
|
NCBI chr17:47,735,120...47,753,126
Ensembl chr17:47,735,120...47,753,126
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| G
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Zmym2
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zinc finger MYM-type containing 2
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affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZMYM2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr15:35,151,356...35,224,528
Ensembl chr15:35,127,994...35,224,941
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| G
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Zmym3
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zinc finger MYM-type containing 3
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affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZMYM3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:70,568,573...70,584,221
Ensembl chr X:70,568,573...70,584,768
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| G
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Zmynd8
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zinc finger, MYND-type containing 8
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affects phosphorylation
|
ISO
|
coumarin affects the phosphorylation of ZMYND8 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 3:174,948,162...175,061,382
Ensembl chr 3:174,948,537...175,061,571
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| G
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Znhit6
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zinc finger, HIT-type containing 6
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increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZNHIT6 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:237,147,014...237,178,279
Ensembl chr 2:237,146,992...237,178,334
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| G
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Zranb2
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zinc finger RANBP2-type containing 2
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZRANB2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:249,232,010...249,245,786
Ensembl chr 2:249,232,010...249,245,780
|
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| G
|
Zranb3
|
zinc finger RANBP2-type containing 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZRANB3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr13:41,993,110...42,148,298
Ensembl chr13:41,992,922...42,148,274
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| G
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Zrsr2
|
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZRSR2 protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:34,179,279...34,201,989
Ensembl chr X:34,179,311...34,201,986
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| G
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Zwilch
|
zwilch kinetochore protein
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increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZWILCH protein
|
CTD |
PMID:35688186 |
|
NCBI chr 8:73,532,968...73,566,214
Ensembl chr 8:73,533,703...73,571,299
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| G
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Zwint
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ZW10 interacting kinetochore protein
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increases expression
|
EXP
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coumarin results in increased expression of ZWINT mRNA
|
CTD |
PMID:18480146 |
|
NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
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| G
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Zxdb
|
zinc finger, X-linked, duplicated B
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increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZXDB protein
|
CTD |
PMID:35688186 |
|
NCBI chr X:63,710,381...63,716,353
Ensembl chr X:63,710,384...63,775,164
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| G
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Zyx
|
zyxin
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increases phosphorylation
|
ISO
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coumarin results in increased phosphorylation of ZYX protein
|
CTD |
PMID:35688186 |
|
NCBI chr 4:72,203,991...72,213,181
Ensembl chr 4:72,204,007...72,213,181
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| G
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Zzef1
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zinc finger ZZ-type and EF-hand domain containing 1
|
increases phosphorylation
|
ISO
|
coumarin results in increased phosphorylation of ZZEF1 protein
|
CTD |
PMID:35688186 |
|
NCBI chr10:57,911,728...58,049,412
Ensembl chr10:57,911,728...58,049,412
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|
| G
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Zzz3
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zinc finger, ZZ-type containing 3
|
decreases phosphorylation
|
ISO
|
coumarin results in decreased phosphorylation of ZZZ3 protein
|
CTD |
PMID:35688186 |
|
NCBI chr 2:243,990,305...244,057,251
Ensembl chr 2:243,990,289...244,056,118
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|
|
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| G
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Akap9
|
A-kinase anchoring protein 9
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increases expression
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ISO
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4-methyl-7-diethylaminocoumarin results in increased expression of AKAP9 mRNA
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CTD |
PMID:19502547 |
|
NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338
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| G
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Ankrd37
|
ankyrin repeat domain 37
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increases expression
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ISO
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4-methyl-7-diethylaminocoumarin results in increased expression of ANKRD37 mRNA
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CTD |
PMID:19502547 |
|
NCBI chr16:53,001,487...53,004,545
Ensembl chr16:52,994,740...53,004,545
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| G
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Ar
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androgen receptor
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multiple interactions affects localization
|
ISO
|
4-methyl-7-diethylaminocoumarin binds to and results in increased activity of AR protein 4-methyl-7-diethylaminocoumarin affects the localization of AR protein
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CTD |
PMID:28478275 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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|
| G
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Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases activity
|
ISO
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4-methyl-7-diethylaminocoumarin results in increased activity of HIF1A protein
|
CTD |
PMID:19502547 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Pfkm
|
phosphofructokinase, muscle
|
increases expression
|
ISO
|
4-methyl-7-diethylaminocoumarin results in increased expression of PFKM mRNA
|
CTD |
PMID:19502547 |
|
NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248
|
|
| G
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Psph
|
phosphoserine phosphatase
|
increases expression
|
ISO
|
4-methyl-7-diethylaminocoumarin results in increased expression of PSPH mRNA
|
CTD |
PMID:19502547 |
|
NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180
|
|
| G
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Tp53
|
tumor protein p53
|
affects activity
|
ISO
|
4-methyl-7-diethylaminocoumarin affects the activity of TP53 protein
|
CTD |
PMID:35435491 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
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Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
ISO
|
4-methyl-7-diethylaminocoumarin results in increased expression of VEGFA protein
|
CTD |
PMID:19502547 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
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|
|
|
| G
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Acp5
|
acid phosphatase 5, tartrate resistant
|
multiple interactions
|
ISO
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crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]]
|
CTD |
PMID:30580027 |
|
NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
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| G
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Acta2
|
actin alpha 2, smooth muscle
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
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CTD |
PMID:32633567 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
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Akt2
|
AKT serine/threonine kinase 2
|
multiple interactions
|
ISO
|
crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA]
|
CTD |
PMID:30580027 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
|
|
| G
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Alpl
|
alkaline phosphatase, biomineralization associated
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multiple interactions
|
EXP
|
crocin inhibits the reaction [Tartrazine results in increased activity of ALPL protein]
|
CTD |
PMID:30657462 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
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Atg5
|
autophagy related 5
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Blood Glucose results in increased expression of ATG5 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased expression of ATG5 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased expression of ATG5 protein]]
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CTD |
PMID:33021114 |
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
|
|
| G
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Bambi
|
BMP and activin membrane-bound inhibitor
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Cisplatin results in decreased expression of BAMBI mRNA]
|
CTD |
PMID:32259551 |
|
NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247
|
|
| G
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Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions increases expression
|
EXP ISO
|
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; crocin inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; crocin inhibits the reaction [Diazinon results in increased expression of BAX protein]; crocin inhibits the reaction [Malathion results in increased expression of BAX protein] crocin inhibits the reaction [Zearalenone results in increased expression of BAX protein] crocin results in increased expression of BAX mRNA
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CTD |
PMID:23523949 PMID:26231423 PMID:27353299 PMID:32886819 PMID:32920515 PMID:35274200 More...
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|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions decreases expression
|
ISO EXP
|
[crocin co-treated with Paraquat] results in decreased expression of BCL2 mRNA; crocin inhibits the reaction [Zearalenone results in decreased expression of BCL2 protein] crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein] crocin results in decreased expression of BCL2 mRNA
|
CTD |
PMID:26231423 PMID:31911963 PMID:32886819 PMID:32920515 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
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Bdnf
|
brain-derived neurotrophic factor
|
increases expression
|
EXP
|
crocin results in increased expression of BDNF mRNA; crocin results in increased expression of BDNF protein
|
CTD |
PMID:24401376 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
| G
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Becn1
|
beclin 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Blood Glucose results in increased expression of BECN1 protein]; crocin inhibits the reaction [Blood Glucose results in increased phosphorylation of BECN1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased expression of BECN1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased expression of BECN1 protein]]
|
CTD |
PMID:33021114 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
|
| G
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Birc5
|
baculoviral IAP repeat-containing 5
|
decreases expression
|
ISO
|
crocin results in decreased expression of BIRC5 mRNA
|
CTD |
PMID:32886819 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
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Casp3
|
caspase 3
|
multiple interactions increases activity increases expression increases cleavage
|
EXP ISO
|
crocin affects the reaction [Ethanol results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; crocin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; crocin inhibits the reaction [Ethanol results in increased activity of CASP3 protein]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; crocin inhibits the reaction [Tartrazine results in increased expression of CASP3 protein] crocin results in increased activity of CASP3 protein crocin results in increased expression of CASP3 mRNA crocin inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA] Acetylcysteine inhibits the reaction [crocin results in increased activity of CASP3 protein]; MIR34A mRNA inhibits the reaction [crocin results in increased activity of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein]
|
CTD |
PMID:23523949 PMID:25637687 PMID:25899501 PMID:26807765 PMID:27353299 PMID:30672053 PMID:31911963 PMID:32870427 PMID:32886819 PMID:32920515 PMID:35085590 PMID:35274200 More...
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|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Casp8
|
caspase 8
|
increases activity
|
ISO
|
crocin results in increased activity of CASP8 protein
|
CTD |
PMID:32886819 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
| G
|
Casp9
|
caspase 9
|
multiple interactions increases activity
|
EXP ISO
|
crocin inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP9 protein] crocin results in increased activity of CASP9 protein
|
CTD |
PMID:27353299 PMID:32886819 PMID:35274200 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Cat
|
catalase
|
multiple interactions increases expression decreases activity increases activity
|
EXP ISO
|
crocin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; crocin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; crocin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; crocin inhibits the reaction [Tartrazine results in decreased activity of CAT protein]; crocin inhibits the reaction [Tartrazine results in decreased expression of CAT protein] crocin results in increased expression of CAT protein crocin results in decreased activity of CAT protein crocin inhibits the reaction [Patulin results in increased activity of CAT protein]; crocin inhibits the reaction [Zearalenone results in increased activity of CAT protein] crocin results in increased activity of CAT protein
|
CTD |
PMID:23488790 PMID:25899501 PMID:26231423 PMID:26584762 PMID:29217164 PMID:29409856 PMID:32870427 PMID:32886819 PMID:32920515 More...
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|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
crocin results in decreased expression of CCND1 mRNA
|
CTD |
PMID:32886819 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ckm
|
creatine kinase, M-type
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Diazinon results in increased activity of CKM protein]
|
CTD |
PMID:23523949 |
|
NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
|
|
| G
|
Col2a1
|
collagen type II alpha 1 chain
|
multiple interactions
|
EXP
|
[geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]
|
CTD |
PMID:24709313 |
|
NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
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| G
|
Creb1
|
cAMP responsive element binding protein 1
|
multiple interactions
|
EXP
|
crocin results in increased expression of and results in increased phosphorylation of CREB1 protein
|
CTD |
PMID:24401376 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
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|
| G
|
Cycs
|
cytochrome c, somatic
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Diazinon affects the localization of CYCS protein]
|
CTD |
PMID:23523949 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
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|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
multiple interactions decreases activity
|
EXP
|
crocin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein] crocin results in decreased activity of CYP2E1 protein
|
CTD |
PMID:25899501 PMID:32633567 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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|
| G
|
Foxp2
|
forkhead box P2
|
increases expression
|
ISO
|
crocin results in increased expression of FOXP2 protein
|
CTD |
PMID:36988377 |
|
NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:44,099,959...44,677,696
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|
| G
|
Glo1
|
glyoxalase 1
|
multiple interactions
|
ISO
|
crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein]
|
CTD |
PMID:30580027 |
|
NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,665,061...8,683,191
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|
| G
|
Got2
|
glutamic-oxaloacetic transaminase 2
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Tartrazine results in increased activity of GOT2 protein]
|
CTD |
PMID:30657462 |
|
NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,180,431...9,206,111
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|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
EXP ISO
|
crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; crocin inhibits the reaction [Cisplatin results in increased activity of GPT protein]; crocin inhibits the reaction [Tartrazine results in increased activity of GPT protein] crocin inhibits the reaction [Zearalenone results in increased expression of GPT protein]
|
CTD |
PMID:26231423 PMID:30657462 PMID:32259551 PMID:32633567 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
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|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein]
|
CTD |
PMID:32920515 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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|
| G
|
Hspa1l
|
heat shock protein family A (Hsp70) member 1 like
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA]
|
CTD |
PMID:25637687 |
|
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
|
|
| G
|
Il10
|
interleukin 10
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Doxorubicin results in decreased expression of IL10 protein]
|
CTD |
PMID:26807765 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
[geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]
|
CTD |
PMID:23488790 PMID:24709313 PMID:26807765 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions decreases expression
|
EXP ISO
|
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; crocin inhibits the reaction [Ethanol results in decreased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein] crocin results in decreased expression of IL6 mRNA
|
CTD |
PMID:23488790 PMID:25637687 PMID:25899501 PMID:29409856 PMID:32633567 PMID:32886819 PMID:32920515 More...
|
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Ins1
|
insulin 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]
|
CTD |
PMID:29409856 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
|
|
| G
|
Jak2
|
Janus kinase 2
|
multiple interactions
|
ISO
|
crocin affects the expression of and affects the phosphorylation of JAK2 protein
|
CTD |
PMID:32886819 |
|
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
|
|
| G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein]
|
CTD |
PMID:32920515 |
|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA]
|
CTD |
PMID:24132704 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Map1lc3b
|
microtubule-associated protein 1 light chain 3 beta
|
multiple interactions
|
EXP
|
[Quercetin co-treated with crocin] inhibits the reaction [Blood Glucose results in increased lipidation of MAP1LC3B protein]; crocin inhibits the reaction [Blood Glucose results in increased lipidation of MAP1LC3B protein]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased lipidation of MAP1LC3B protein]]
|
CTD |
PMID:33021114 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
decreases phosphorylation multiple interactions
|
ISO EXP
|
crocin results in decreased phosphorylation of MAPK1 protein crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK1 protein]
|
CTD |
PMID:24132704 PMID:28689058 PMID:32886819 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions decreases phosphorylation
|
EXP ISO
|
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK3 protein] crocin results in decreased phosphorylation of MAPK3 protein crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]
|
CTD |
PMID:24132704 PMID:28689058 PMID:30580027 PMID:32886819 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Mir122
|
microRNA 122
|
multiple interactions decreases expression
|
EXP ISO
|
crocin inhibits the reaction [bisphenol A results in increased expression of MIR122 mRNA] crocin results in decreased expression of MIR122
|
CTD |
PMID:28689058 PMID:36988377 |
|
NCBI chr18:61,028,817...61,028,901
|
|
| G
|
Mir29b1
|
microRNA 29b-1
|
increases expression multiple interactions
|
EXP
|
crocin results in increased expression of MIR29B1 mRNA Cisplatin inhibits the reaction [crocin results in increased expression of MIR29B1 mRNA]; crocin inhibits the reaction [Cisplatin results in decreased expression of MIR29B1 mRNA]
|
CTD |
PMID:32259551 |
|
NCBI chr 4:60,618,334...60,618,414
|
|
| G
|
Mir34a
|
microRNA 34a
|
multiple interactions
|
ISO
|
MIR34A mRNA inhibits the reaction [crocin results in increased activity of CASP3 protein]; MIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein]
|
CTD |
PMID:35085590 |
|
NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053
|
|
| G
|
Mir9-1
|
microRNA 9-1
|
multiple interactions increases expression
|
EXP
|
Cisplatin inhibits the reaction [crocin results in increased expression of MIR9-1 mRNA]; crocin inhibits the reaction [Cisplatin results in decreased expression of MIR9-1 mRNA]
|
CTD |
PMID:32259551 |
|
NCBI chr 2:175,974,971...175,975,059
|
|
| G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Ethanol results in increased activity of MPO protein]
|
CTD |
PMID:25637687 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
decreases expression
|
ISO
|
crocin results in decreased expression of MYC mRNA
|
CTD |
PMID:32886819 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Mycn
|
MYCN proto-oncogene, bHLH transcription factor
|
decreases response to substance multiple interactions decreases expression
|
ISO
|
MYCN results in decreased susceptibility to crocin crocin results in decreased expression of and results in decreased stability of MYCN mRNA; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein] crocin results in decreased expression of MYCN protein
|
CTD |
PMID:30672053 |
|
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508
|
|
| G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 protein]
|
CTD |
PMID:32259551 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; crocin inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 protein]
|
CTD |
PMID:32259551 PMID:32920515 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein]
|
CTD |
PMID:32920515 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Ostm1
|
osteoclastogenesis associated transmembrane protein 1
|
multiple interactions
|
ISO
|
[crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA]
|
CTD |
PMID:30580027 |
|
NCBI chr20:47,653,696...47,769,248
Ensembl chr20:47,653,670...47,769,237
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions increases cleavage
|
ISO
|
MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein]
|
CTD |
PMID:30672053 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG protein]
|
CTD |
PMID:32633567 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Prkab1
|
protein kinase AMP-activated non-catalytic subunit beta 1
|
multiple interactions
|
EXP
|
crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased phosphorylation of PRKAB1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased phosphorylation of PRKAB1 protein]]
|
CTD |
PMID:33021114 |
|
NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions decreases expression
|
EXP ISO
|
crocin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein] crocin results in decreased expression of PTGS2 mRNA
|
CTD |
PMID:23488790 PMID:32886819 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Ptpn4
|
protein tyrosine phosphatase, non-receptor type 4
|
multiple interactions increases expression
|
ISO
|
MIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein]
|
CTD |
PMID:35085590 |
|
NCBI chr13:33,324,808...33,504,957
Ensembl chr13:33,324,808...33,504,957
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein]
|
CTD |
PMID:29409856 PMID:32920515 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Smad2
|
SMAD family member 2
|
decreases expression multiple interactions
|
EXP
|
crocin results in decreased expression of SMAD2 protein Cisplatin inhibits the reaction [crocin results in decreased expression of SMAD2 protein]; crocin inhibits the reaction [Cisplatin results in increased expression of SMAD2 protein]
|
CTD |
PMID:32259551 |
|
NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
|
|
| G
|
Snca
|
synuclein alpha
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; crocin inhibits the reaction [Malathion results in increased expression of SNCA protein]
|
CTD |
PMID:35274200 |
|
NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
increases expression multiple interactions
|
EXP
|
crocin results in increased expression of SOD1 protein crocin inhibits the reaction [Tartrazine results in decreased expression of SOD1 protein]
|
CTD |
PMID:32870427 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Spry2
|
sprouty RTK signaling antagonist 2
|
increases expression
|
ISO
|
crocin results in increased expression of SPRY2 protein
|
CTD |
PMID:36988377 |
|
NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074
|
|
| G
|
Sqstm1
|
sequestosome 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Blood Glucose results in decreased expression of SQSTM1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in decreased expression of SQSTM1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in decreased expression of SQSTM1 protein]]
|
CTD |
PMID:33021114 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
|
|
| G
|
Stat3
|
signal transducer and activator of transcription 3
|
multiple interactions
|
ISO
|
crocin affects the expression of and affects the phosphorylation of STAT3 protein
|
CTD |
PMID:32886819 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
|
|
| G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Blood Glucose results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; crocin promotes the reaction [Quercetin inhibits the reaction [Blood Glucose results in increased expression of TGFB1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; Quercetin promotes the reaction [crocin inhibits the reaction [Blood Glucose results in increased expression of TGFB1 protein]]
|
CTD |
PMID:29409856 PMID:32259551 PMID:32633567 PMID:33021114 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
| G
|
Tgfbr1
|
transforming growth factor, beta receptor 1
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Cisplatin results in increased expression of TGFBR1 protein]
|
CTD |
PMID:32259551 |
|
NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260
|
|
| G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
EXP
|
crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]
|
CTD |
PMID:29409856 PMID:32259551 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions decreases expression
|
EXP ISO
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crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; crocin inhibits the reaction [Ethanol results in decreased expression of TNF protein] crocin results in decreased expression of TNF mRNA
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CTD |
PMID:23488790 PMID:25637687 PMID:25899501 PMID:26807765 PMID:32633567 PMID:32886819 PMID:32920515 More...
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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| G
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Tnfsf11
|
TNF superfamily member 11
|
multiple interactions
|
ISO
|
[crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein]; crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]]
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CTD |
PMID:30580027 |
|
NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
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| G
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Tnnt2
|
troponin T2, cardiac type
|
multiple interactions
|
EXP
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crocin inhibits the reaction [Doxorubicin results in increased expression of TNNT2 protein]
|
CTD |
PMID:26807765 |
|
NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125
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| G
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Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
crocin inhibits the reaction [Paraquat results in increased expression of TRP53 mRNA]; crocin inhibits the reaction [Zearalenone results in increased expression of TRP53 protein]
|
CTD |
PMID:26231423 PMID:31911963 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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|
| G
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Traf6
|
TNF receptor associated factor 6
|
multiple interactions
|
ISO
|
crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA]
|
CTD |
PMID:30580027 |
|
NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328
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|
| G
|
Vgf
|
VGF nerve growth factor inducible
|
increases expression
|
EXP
|
crocin results in increased expression of VGF protein
|
CTD |
PMID:24401376 |
|
NCBI chr12:25,274,004...25,281,803
Ensembl chr12:25,273,333...25,282,703
|
|
|
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| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
ISO
|
Gentian Violet promotes the reaction [TP53 protein results in increased expression of BAX mRNA]; pifithrin inhibits the reaction [Gentian Violet promotes the reaction [TP53 protein results in increased expression of BAX mRNA]]
|
CTD |
PMID:24535435 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bbc3
|
Bcl-2 binding component 3
|
multiple interactions
|
ISO
|
Gentian Violet promotes the reaction [TP53 protein binds to BBC3 promoter]; Gentian Violet promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]; pifithrin inhibits the reaction [Gentian Violet promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]]
|
CTD |
PMID:24535435 |
|
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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|
| G
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Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
ISO
|
Gentian Violet results in decreased expression of BCL2 protein
|
CTD |
PMID:27373978 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO
|
Gentian Violet results in increased cleavage of and results in increased activity of CASP3 protein
|
CTD |
PMID:26177467 PMID:27373978 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Casp7
|
caspase 7
|
multiple interactions
|
ISO
|
Gentian Violet results in increased cleavage of and results in increased activity of CASP7 protein
|
CTD |
PMID:26177467 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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|
| G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
Gentian Violet results in decreased expression of CCND1 protein
|
CTD |
PMID:26177467 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions
|
ISO
|
Gentian Violet promotes the reaction [TP53 protein binds to CDKN1A promoter]; Gentian Violet promotes the reaction [TP53 protein results in increased expression of CDKN1A mRNA]
|
CTD |
PMID:24535435 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
Gentian Violet inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
|
CTD |
PMID:23769903 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Ikbke
|
inhibitor of nuclear factor kappa B kinase subunit epsilon
|
decreases expression
|
ISO
|
Gentian Violet results in decreased expression of IKBKE protein
|
CTD |
PMID:26177467 |
|
NCBI chr13:45,264,404...45,290,737
Ensembl chr13:45,264,412...45,289,396
|
|
| G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases activity
|
ISO
|
Gentian Violet results in decreased activity of KCNH2 protein
|
CTD |
PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
|
|
| G
|
Nox1
|
NADPH oxidase 1
|
multiple interactions
|
ISO
|
Gentian Violet inhibits the reaction [NOX1 protein results in decreased activity of TP53 protein]
|
CTD |
PMID:24535435 |
|
NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
increases cleavage
|
ISO
|
Gentian Violet results in increased cleavage of PARP1 protein
|
CTD |
PMID:24535435 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Prdx3
|
peroxiredoxin 3
|
multiple interactions
|
ISO
|
Gentian Violet promotes the reaction [Thiostrepton affects the expression of PRDX3 protein modified form]
|
CTD |
PMID:22761781 |
|
NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300
|
|
| G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
Gentian Violet inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
|
|
| G
|
Sox2
|
SRY-box transcription factor 2
|
multiple interactions
|
ISO
|
[Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein] inhibits the reaction [STAT3 protein binds to SOX2 promoter]
|
CTD |
PMID:27373978 |
|
NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350
|
|
| G
|
Stat3
|
signal transducer and activator of transcription 3
|
multiple interactions
|
ISO
|
[Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein] inhibits the reaction [STAT3 protein binds to SOX2 promoter]; Gentian Violet results in decreased phosphorylation of and affects the localization of STAT3 protein
|
CTD |
PMID:27373978 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions affects activity
|
ISO
|
Gentian Violet inhibits the reaction [NOX1 protein results in decreased activity of TP53 protein]; Gentian Violet promotes the reaction [TP53 protein binds to BBC3 promoter]; Gentian Violet promotes the reaction [TP53 protein binds to CDKN1A promoter]; Gentian Violet promotes the reaction [TP53 protein binds to TP53AIP1 promoter]; Gentian Violet promotes the reaction [TP53 protein results in increased expression of BAX mRNA]; Gentian Violet promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]; Gentian Violet promotes the reaction [TP53 protein results in increased expression of CDKN1A mRNA]; Gentian Violet results in increased stability of and results in increased activity of TP53 protein; pifithrin inhibits the reaction [Gentian Violet promotes the reaction [TP53 protein results in increased expression of BAX mRNA]]; pifithrin inhibits the reaction [Gentian Violet promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]] Gentian Violet affects the activity of TP53 protein
|
CTD |
PMID:24535435 PMID:35435491 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Txn2
|
thioredoxin 2
|
decreases expression
|
ISO
|
Gentian Violet results in decreased expression of TXN2 protein
|
CTD |
PMID:22761781 |
|
NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:111,386,805...111,390,022
|
|
|
|
| G
|
A4galt
|
alpha 1,4-galactosyltransferase
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [IL1B protein results in increased expression of A4GALT mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of A4GALT mRNA]
|
CTD |
PMID:16819191 |
|
NCBI chr 7:116,248,571...116,272,917
Ensembl chr 7:116,247,880...116,273,171
|
|
| G
|
Aars1
|
alanyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of AARS1 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
|
|
| G
|
Abca1
|
ATP binding cassette subfamily A member 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]; Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]
|
CTD |
PMID:33952798 |
|
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
affects response to substance decreases response to substance decreases expression multiple interactions
|
ISO
|
ABCB1 affects the susceptibility to Curcumin ABCB1 protein results in decreased susceptibility to Curcumin Curcumin analog results in decreased expression of ABCB1 protein; Curcumin results in decreased expression of ABCB1 mRNA; Curcumin results in decreased expression of ABCB1B mRNA [Curcumin co-treated with Calcitriol] inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Calcitriol promotes the reaction [Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA] [Calcitriol co-treated with Curcumin] inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; [Curcumin co-treated with Calcitriol] inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]; [Curcumin co-treated with Paclitaxel] results in increased expression of ABCB1 protein; [sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA; Calcitriol inhibits the reaction [[Curcumin co-treated with Paclitaxel] results in increased expression of ABCB1 protein]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [[Calcitriol co-treated with Paclitaxel] results in increased expression of ABCB1 mRNA]; Curcumin inhibits the reaction [[Calcitriol co-treated with Paclitaxel] results in increased expression of ABCB1 protein]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein
|
CTD |
PMID:15476675 PMID:17121181 PMID:18200517 PMID:18385293 PMID:18414057 PMID:18439772 PMID:20816778 PMID:26689174 PMID:27318188 PMID:31628941 More...
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|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcb1b
|
ATP-binding cassette, sub-family B member 1B
|
multiple interactions decreases expression
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Curcumin results in decreased expression of ABCB1B protein]; [Curcumin results in decreased expression of ABCB1B protein] which results in increased susceptibility to Doxorubicin; Curcumin inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mRNA] Curcumin results in decreased expression of ABCB1B mRNA; Curcumin results in decreased expression of ABCB1B protein
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CTD |
PMID:18006147 |
|
NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567
|
|
| G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
decreases activity decreases expression
|
ISO
|
Curcumin results in decreased activity of ABCC1 protein Curcumin analog results in decreased expression of ABCC1 mRNA
|
CTD |
PMID:15885658 PMID:16021489 PMID:26409325 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
decreases activity multiple interactions
|
ISO
|
Curcumin results in decreased activity of ABCC2 protein [Curcumin co-treated with Acetaminophen] results in increased expression of ABCC2 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of ABCC2 protein
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CTD |
PMID:15885658 PMID:35243748 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Abcc4
|
ATP binding cassette subfamily C member 4
|
multiple interactions
|
ISO
|
[Curcumin co-treated with Acetaminophen] results in increased expression of ABCC4 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of ABCC4 protein
|
CTD |
PMID:35243748 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
|
|
| G
|
Abcc5
|
ATP binding cassette subfamily C member 5
|
multiple interactions
|
ISO
|
[Curcumin analog binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; [Curcumin binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; Curcumin analog binds to and results in decreased activity of ABCC5 protein; Curcumin analog inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]; Curcumin binds to and results in decreased activity of ABCC5 protein; Curcumin inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]
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CTD |
PMID:23978416 |
|
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
|
|
| G
|
Abcg1
|
ATP binding cassette subfamily G member 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of ABCG1 mRNA
|
CTD |
PMID:16713233 PMID:21594647 |
|
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563
|
|
| G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions decreases expression increases expression
|
ISO
|
AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein] Curcumin results in decreased expression of ABCG2 mRNA
|
CTD |
PMID:17077187 PMID:33539684 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
|
|
| G
|
Acaca
|
acetyl-CoA carboxylase alpha
|
increases phosphorylation decreases expression affects expression multiple interactions
|
ISO EXP
|
Curcumin results in increased phosphorylation of ACACA protein Curcumin results in decreased expression of ACACA mRNA Curcumin affects the expression of ACACA mRNA Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACA mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACA protein]; Curcumin inhibits the reaction [Dietary Fats results in decreased phosphorylation of ACACA protein]
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CTD |
PMID:18790744 PMID:19297423 PMID:27208389 PMID:37701206 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
|
|
| G
|
Acacb
|
acetyl-CoA carboxylase beta
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACB mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACB protein]
|
CTD |
PMID:37701206 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214
|
|
| G
|
Ace
|
angiotensin I converting enzyme
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Paraquat affects the expression of ACE protein]
|
CTD |
PMID:10666014 |
|
NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942
|
|
| G
|
Ace2
|
angiotensin converting enzyme 2
|
multiple interactions affects binding
|
EXP ISO
|
Curcumin inhibits the reaction [AGT protein results in increased expression of ACE2 protein] Curcumin binds to ACE2 protein
|
CTD |
PMID:26648693 PMID:34138966 |
|
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596
|
|
| G
|
Ache
|
acetylcholinesterase
|
decreases activity multiple interactions
|
EXP ISO
|
Curcumin results in decreased activity of ACHE protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of ACHE protein] [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of ACHE protein]; Curcumin inhibits the reaction [Rotenone results in decreased activity of ACHE protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of ACHE protein]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein] Curcumin inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; Curcumin inhibits the reaction [aluminum acetate results in decreased activity of ACHE protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of ACHE mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of ACHE protein]; Curcumin inhibits the reaction [lead acetate results in decreased activity of ACHE protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
|
CTD |
PMID:18809455 PMID:20369229 PMID:21839772 PMID:22783142 PMID:25199698 PMID:25496357 PMID:28527659 PMID:31714633 PMID:31820278 PMID:36924976 More...
|
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
|
|
| G
|
Ackr3
|
atypical chemokine receptor 3
|
increases expression
|
ISO
|
Curcumin results in increased expression of ACKR3 mRNA
|
CTD |
PMID:21594647 |
|
NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214
|
|
| G
|
Acly
|
ATP citrate lyase
|
affects expression decreases expression
|
ISO EXP
|
Curcumin affects the expression of ACLY mRNA Curcumin results in decreased expression of ACLY mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
|
|
| G
|
Aco2
|
aconitase 2
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Potassium Dichromate results in decreased activity of ACO2 protein]
|
CTD |
PMID:25130536 |
|
NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
|
|
| G
|
Acsl4
|
acyl-CoA synthetase long-chain family member 4
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Firemaster BP-6 results in increased expression of ACSL4 protein]
|
CTD |
PMID:39934342 |
|
NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261
|
|
| G
|
Acta2
|
actin alpha 2, smooth muscle
|
decreases expression multiple interactions
|
EXP ISO
|
Curcumin results in decreased expression of ACTA2 mRNA; Curcumin results in decreased expression of ACTA2 protein Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of ACTA2 mRNA]; Arsenic Trioxide promotes the reaction [Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]; Curcumin promotes the reaction [Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 mRNA]]
|
CTD |
PMID:17355460 PMID:17531121 PMID:18006644 PMID:22683883 PMID:27363783 PMID:31612257 PMID:32718261 PMID:35716765 More...
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|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Adam17
|
ADAM metallopeptidase domain 17
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [TNF protein results in increased expression of ADAM17 mRNA]
|
CTD |
PMID:17666914 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344
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| G
|
Adamts4
|
ADAM metallopeptidase with thrombospondin type 1 motif, 4
|
increases expression
|
ISO
|
Curcumin results in increased expression of ADAMTS4 mRNA
|
CTD |
PMID:18321735 |
|
NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514
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|
| G
|
Adcy9
|
adenylate cyclase 9
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ADCY9 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr10:11,645,373...11,768,462
Ensembl chr10:11,645,282...11,765,792
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|
| G
|
Adgre1
|
adhesion G protein-coupled receptor E1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ADGRE1 mRNA
|
CTD |
PMID:18403477 |
|
NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959
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|
| G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
increases expression multiple interactions affects expression
|
ISO EXP
|
Curcumin results in increased expression of ADIPOQ mRNA; Curcumin results in increased expression of ADIPOQ protein Curcumin inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein] Curcumin affects the expression of ADIPOQ mRNA Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]
|
CTD |
PMID:18403477 PMID:26713546 PMID:27208389 PMID:28595985 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
| G
|
Adora2a
|
adenosine A2a receptor
|
multiple interactions
|
ISO
|
[Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of ADORA2A mRNA]; Curcumin inhibits the reaction [Rotenone results in increased expression of ADORA2A mRNA]
|
CTD |
PMID:31820278 |
|
NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
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|
| G
|
Ager
|
advanced glycosylation end product-specific receptor
|
multiple interactions
|
EXP
|
bisphenol A diglycidyl ether inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein]]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein]
|
CTD |
PMID:29480285 |
|
NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
|
|
| G
|
Agr2
|
anterior gradient 2, protein disulphide isomerase family member
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of AGR2 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677
|
|
| G
|
Agt
|
angiotensinogen
|
multiple interactions
|
EXP ISO
|
[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of RELA protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of KIT protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of PCNA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased acetylation of TP53 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]]; Curcumin inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of and results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of and results in increased acetylation of TP53 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]; Curcumin inhibits the reaction [AGT protein results in decreased expression of AGTR2 protein]; Curcumin inhibits the reaction [AGT protein results in increased expression of ACE2 protein]; Curcumin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [AGT protein results in increased phosphorylation of SMAD2 protein]; Curcumin inhibits the reaction [AGT protein results in increased phosphorylation of SMAD3 protein]; Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein] [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of AGT protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of AGT protein]
|
CTD |
PMID:26612707 PMID:26648693 PMID:31820278 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Agtr2
|
angiotensin II receptor, type 2
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [AGT protein results in decreased expression of AGTR2 protein]
|
CTD |
PMID:26648693 |
|
NCBI chr X:116,914,320...116,918,504
Ensembl chr X:116,913,656...116,918,745
|
|
| G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions affects binding increases degradation
|
ISO
|
AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein] Curcumin binds to AHR protein Curcumin results in increased degradation of AHR protein [Curcumin co-treated with resveratrol] inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; Curcumin inhibits the reaction [Benzo(a)pyrene affects the localization of AHR protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of AHR protein]; Curcumin inhibits the reaction [Methylcholanthrene binds to AHR protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [AHR protein co-treated with ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AHR protein]; Curcumin promotes the reaction [Tetrachlorodibenzodioxin results in increased localization of AHR protein]
|
CTD |
PMID:17077187 PMID:17880909 PMID:18321868 PMID:19018768 PMID:25632966 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
| G
|
Ak1
|
adenylate kinase 1
|
multiple interactions
|
ISO
|
[ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of AK1 protein
|
CTD |
PMID:25866362 |
|
NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757
|
|
| G
|
Akap6
|
A-kinase anchoring protein 6
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of AKAP6 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA]
|
CTD |
PMID:18200517 PMID:18421014 |
|
NCBI chr 6:75,919,350...76,359,667
Ensembl chr 6:75,919,513...76,355,036
|
|
| G
|
Akr1b1
|
aldo-keto reductase family 1 member B1
|
increases expression multiple interactions increases activity
|
ISO EXP
|
Curcumin results in increased expression of AKR1B1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Curcumin results in increased expression of AKR1B1 protein]; AKT1 protein affects the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 protein]; pyrazolanthrone inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; SB 203580 inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA] Curcumin results in increased expression of AKR1B1 mRNA; Curcumin results in increased expression of AKR1B1 protein Curcumin results in increased activity of AKR1B1 protein
|
CTD |
PMID:17640564 PMID:18200517 PMID:18299980 PMID:18588981 |
|
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
|
|
| G
|
Akr1b15
|
aldo-keto reductase family 1 member B15
|
increases expression
|
EXP
|
Curcumin results in increased expression of AKR1B8 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions decreases phosphorylation affects phosphorylation decreases expression increases expression increases phosphorylation decreases activity
|
ISO EXP
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased phosphorylation of AKT1 protein]; 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [ATF4 protein binds to AKT1 protein]; Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of AKT1 protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of AKT1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased phosphorylation of AKT1 protein]; Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]]; lonidamine promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; MIR532 affects the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] Curcumin affects the phosphorylation of AKT1 protein Curcumin analog results in decreased expression of AKT1 mRNA; Curcumin results in decreased expression of AKT1 protein Curcumin results in increased expression of AKT1 protein AKT1 protein affects the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of AKT1 protein; MIR206 affects the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] AKT1 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] Curcumin results in decreased activity of AKT1 protein
|
CTD |
PMID:16023083 PMID:16219905 PMID:17289836 PMID:17291458 PMID:17332930 PMID:17372590 PMID:17535857 PMID:17596214 PMID:17640564 PMID:17640567 PMID:17918158 PMID:18006147 PMID:18214481 PMID:18660423 PMID:18790744 PMID:19372569 PMID:20605902 PMID:20727180 PMID:20938987 PMID:23222814 PMID:23452621 PMID:23555722 PMID:24211270 PMID:24365254 PMID:24831732 PMID:25541178 PMID:26409325 PMID:27208389 PMID:27966075 PMID:34577062 PMID:34634291 PMID:35752269 PMID:36640941 PMID:37471645 PMID:38764151 More...
|
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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|
| G
|
Akt2
|
AKT serine/threonine kinase 2
|
multiple interactions decreases phosphorylation decreases expression
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of AKT2 protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of AKT2 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased phosphorylation of AKT2 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of AKT2 protein ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein] Curcumin analog results in decreased expression of AKT2 mRNA
|
CTD |
PMID:23452621 PMID:26409325 PMID:36640941 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
|
|
| G
|
Akt3
|
AKT serine/threonine kinase 3
|
multiple interactions decreases expression decreases phosphorylation
|
ISO
|
ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein] Curcumin results in decreased expression of AKT3 protein 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased phosphorylation of AKT3 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of AKT3 protein; MIR532 affects the reaction [Curcumin results in decreased expression of AKT3 protein]
|
CTD |
PMID:36640941 PMID:37471645 |
|
NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020
|
|
| G
|
Alad
|
aminolevulinate dehydratase
|
multiple interactions
|
EXP ISO
|
[Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of ALAD protein]; Curcumin inhibits the reaction [Arsenic results in decreased activity of ALAD protein] Curcumin inhibits the reaction [Bortezomib results in decreased activity of ALAD protein]; Curcumin inhibits the reaction [lead acetate results in decreased activity of ALAD protein]
|
CTD |
PMID:22704994 PMID:23292317 PMID:25352650 |
|
NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
|
|
| G
|
Alas1
|
5'-aminolevulinate synthase 1
|
increases expression
|
EXP
|
Curcumin results in increased expression of ALAS1 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642
|
|
| G
|
Alb
|
albumin
|
multiple interactions
|
EXP
|
[Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in decreased expression of ALB protein]; [Curcumin analog co-treated with Hydrogels] results in increased expression of ALB protein; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Thioacetamide results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ALB protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in decreased expression of ALB protein]]
|
CTD |
PMID:18204486 PMID:18809455 PMID:20804811 PMID:24704557 PMID:27288928 PMID:32718261 More...
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|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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|
| G
|
Alcam
|
activated leukocyte cell adhesion molecule
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ALCAM mRNA
|
CTD |
PMID:33539684 |
|
NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
multiple interactions decreases expression
|
ISO
|
[Calcitriol co-treated with Curcumin] promotes the reaction [Paclitaxel results in decreased expression of ALDH1A1 mRNA]; [Calcitriol co-treated with Paclitaxel] promotes the reaction [Curcumin results in decreased expression of ALDH1A1 mRNA]; [Curcumin co-treated with Calcitriol] inhibits the reaction [Paclitaxel results in decreased expression of ALDH1A1 protein]; [Curcumin co-treated with Paclitaxel] promotes the reaction [Calcitriol results in decreased expression of ALDH1A1 mRNA]; Curcumin promotes the reaction [Paclitaxel results in decreased expression of ALDH1A1 protein]; Paclitaxel promotes the reaction [Curcumin results in decreased expression of ALDH1A1 mRNA] [Calcitriol co-treated with Curcumin] inhibits the reaction [Paclitaxel results in decreased expression of ALDH1A1 protein] Curcumin results in decreased expression of ALDH1A1 mRNA; Curcumin results in decreased expression of ALDH1A1 protein
|
CTD |
PMID:31628941 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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|
| G
|
Aldoa
|
aldolase, fructose-bisphosphate A
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ALDOA mRNA
|
CTD |
PMID:16880289 |
|
NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211
|
|
| G
|
Aldoc
|
aldolase, fructose-bisphosphate C
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ALDOC mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
|
|
| G
|
Alox5
|
arachidonate 5-lipoxygenase
|
multiple interactions decreases activity
|
EXP
|
[Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein Curcumin results in decreased activity of ALOX5 protein
|
CTD |
PMID:16956363 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
|
|
| G
|
Amfr
|
autocrine motility factor receptor
|
increases expression
|
ISO
|
Curcumin results in increased expression of AMFR mRNA; Curcumin results in increased expression of AMFR protein
|
CTD |
PMID:38229314 |
|
NCBI chr19:11,002,451...11,038,182
Ensembl chr19:11,002,101...11,038,364
|
|
| G
|
Ampd1
|
adenosine monophosphate deaminase 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of AMPD1 protein]
|
CTD |
PMID:36924976 |
|
NCBI chr 2:193,287,219...193,308,446
Ensembl chr 2:193,287,265...193,308,443
|
|
| G
|
Ampd3
|
adenosine monophosphate deaminase 3
|
increases expression
|
EXP
|
Curcumin results in increased expression of AMPD3 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608
|
|
| G
|
Ankrd37
|
ankyrin repeat domain 37
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ANKRD37 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr16:53,001,487...53,004,545
Ensembl chr16:52,994,740...53,004,545
|
|
| G
|
Ankrd50
|
ankyrin repeat domain containing 50
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ANKRD50 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr 2:123,394,311...123,428,788
Ensembl chr 2:123,396,606...123,427,340
|
|
| G
|
Ankzf1
|
ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ANKZF1 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 9:84,136,862...84,143,830
Ensembl chr 9:84,136,862...84,145,091
|
|
| G
|
Aoc1
|
amine oxidase, copper containing 1
|
multiple interactions
|
EXP ISO
|
Curcumin inhibits the reaction [Methotrexate results in increased activity of AOC1 protein] Curcumin inhibits the reaction [deoxynivalenol results in increased activity of AOC1 protein]
|
CTD |
PMID:20885979 PMID:35817260 |
|
NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704
|
|
| G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
increases expression multiple interactions
|
ISO EXP
|
Curcumin results in increased expression of APAF1 protein Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of APAF1 mRNA]
|
CTD |
PMID:17277231 PMID:20869986 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of APC mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
| G
|
Apoe
|
apolipoprotein E
|
affects expression
|
ISO
|
Curcumin affects the expression of APOE mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
|
|
| G
|
App
|
amyloid beta precursor protein
|
multiple interactions increases expression
|
ISO EXP
|
Curcumin affects the reaction [APP protein binds to APP protein]; Curcumin inhibits the reaction [Copper results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP protein] [Curcumin analog co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; [Curcumin co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; Curcumin analog inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin analog promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein]; Curcumin inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein] Curcumin results in increased expression of APP mRNA
|
CTD |
PMID:18537544 PMID:18583042 PMID:27793699 PMID:30946834 PMID:31521693 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Aqp3
|
aquaporin 3 (Gill blood group)
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of AQP3 protein Curcumin inhibits the reaction [EGF protein results in increased expression of AQP3 protein]
|
CTD |
PMID:18214481 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
|
|
| G
|
Aqp9
|
aquaporin 9
|
increases expression
|
ISO
|
Curcumin results in increased expression of AQP9 mRNA; Curcumin results in increased expression of AQP9 protein
|
CTD |
PMID:34675983 |
|
NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240
|
|
| G
|
Ar
|
androgen receptor
|
multiple interactions increases expression decreases activity decreases expression
|
ISO
|
[[Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter] which results in increased expression of AR mRNA; [[Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter] which results in increased expression of AR protein; [Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; Curcumin inhibits the reaction [AR protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to TMPRSS2 enhancer]]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR protein]; Curcumin promotes the reaction [Quercetin results in increased expression of AR mRNA]; Curcumin promotes the reaction [Quercetin results in increased expression of AR protein]; Quercetin promotes the reaction [Curcumin results in increased expression of AR mRNA]; Quercetin promotes the reaction [Curcumin results in increased expression of AR protein] Curcumin results in increased expression of AR mRNA; Curcumin results in increased expression of AR protein Curcumin results in decreased activity of AR protein Curcumin results in decreased expression of AR mRNA; Curcumin results in decreased expression of AR protein
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CTD |
PMID:12497104 PMID:18676361 PMID:18719366 PMID:22258452 PMID:27132804 |
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NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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| G
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Arhgap24
|
Rho GTPase activating protein 24
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA]
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CTD |
PMID:18200517 |
|
NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950
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| G
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Arhgap30
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Rho GTPase activating protein 30
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decreases expression
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ISO
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Curcumin results in decreased expression of ARHGAP30 mRNA
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CTD |
PMID:18421014 |
|
NCBI chr13:86,354,448...86,376,552
Ensembl chr13:86,354,547...86,376,888
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| G
|
Arhgdib
|
Rho GDP dissociation inhibitor beta
|
multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA]
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CTD |
PMID:18200517 |
|
NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068
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| G
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Arnt
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aryl hydrocarbon receptor nuclear translocator
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multiple interactions increases degradation decreases expression
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ISO
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Acetylcysteine inhibits the reaction [Curcumin results in increased degradation of ARNT protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in increased degradation of ARNT protein]; Curcumin results in increased ubiquitination of and results in increased degradation of ARNT protein Curcumin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [AHR protein co-treated with ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of ARNT protein] Curcumin results in decreased expression of ARNT protein
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CTD |
PMID:16880289 PMID:17880909 PMID:18682687 PMID:19018768 |
|
NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
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|
| G
|
Atf1
|
activating transcription factor 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of ATF1 mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485
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|
| G
|
Atf2
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activating transcription factor 2
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decreases expression
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ISO
|
Curcumin analog results in decreased expression of ATF2 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745
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| G
|
Atf3
|
activating transcription factor 3
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increases expression
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ISO
|
Curcumin results in increased expression of ATF3 mRNA; Curcumin results in increased expression of ATF3 protein
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CTD |
PMID:15713895 PMID:18555241 PMID:18719366 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
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|
| G
|
Atf4
|
activating transcription factor 4
|
multiple interactions decreases expression
|
ISO
|
ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein] ATF4 inhibits the reaction [Curcumin results in decreased expression of ATF4 protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of HK2 protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of LDHA protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of PKM protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of SLC2A1 protein]; Curcumin inhibits the reaction [ATF4 protein binds to AKT1 protein]; Curcumin inhibits the reaction [ATF4 protein binds to ATG4B protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of ATF4 protein]
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CTD |
PMID:36640941 |
|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
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| G
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Atf6
|
activating transcription factor 6
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increases expression
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ISO
|
Curcumin results in increased expression of ATF6 protein Curcumin results in increased expression of ATF6 mRNA
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CTD |
PMID:21793155 PMID:29723631 |
|
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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|
| G
|
Atg4b
|
autophagy related 4B, cysteine peptidase
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of ATG4B protein 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of ATG4B protein]; Curcumin inhibits the reaction [ATF4 protein binds to ATG4B protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of ATG4B protein]
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CTD |
PMID:36640941 |
|
NCBI chr 9:101,729,772...101,761,456
Ensembl chr 9:101,726,782...101,761,622
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|
| G
|
Atg5
|
autophagy related 5
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decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of ATG5 protein Curcumin inhibits the reaction [Tunicamycin results in increased expression of ATG5 protein]
|
CTD |
PMID:36640941 |
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
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|
| G
|
Atm
|
ATM serine/threonine kinase
|
multiple interactions increases phosphorylation
|
ISO
|
[Isoflavones co-treated with Curcumin] results in increased phosphorylation of ATM protein Curcumin results in increased phosphorylation of ATM protein
|
CTD |
PMID:19401701 PMID:21134073 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
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|
| G
|
Aurka
|
aurora kinase A
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of AURKA mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
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|
| G
|
Aurkb
|
aurora kinase B
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of AURKB mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
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|
| G
|
Axin1
|
axin 1
|
multiple interactions increases expression
|
EXP
|
Curcumin inhibits the reaction [bisphenol A results in decreased expression of AXIN1 mRNA] Curcumin results in increased expression of AXIN1 mRNA
|
CTD |
PMID:25963729 |
|
NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,667,958...15,720,092
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|
| G
|
B3galt6
|
Beta-1,3-galactosyltransferase 6
|
increases expression
|
ISO
|
Curcumin results in increased expression of B3GALT6 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 5:171,866,428...171,868,564
Ensembl chr 5:171,864,094...171,874,789
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|
| G
|
Bace1
|
beta-secretase 1
|
multiple interactions increases expression
|
ISO
|
Curcumin inhibits the reaction [Copper results in increased expression of BACE1 mRNA]; Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of BACE1 mRNA] Curcumin results in increased expression of BACE1 mRNA
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CTD |
PMID:18583042 PMID:31521693 |
|
NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918
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|
| G
|
Bad
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BCL2-associated agonist of cell death
|
increases expression multiple interactions
|
ISO EXP
|
Curcumin results in increased expression of BAD mRNA; Curcumin results in increased expression of BAD protein Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAD protein] [arsenic trioxide co-treated with Curcumin] results in increased expression of BAD protein
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CTD |
PMID:15569404 PMID:19235267 PMID:27430728 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
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|
| G
|
Bak1
|
BCL2-antagonist/killer 1
|
multiple interactions increases expression increases response to substance decreases expression
|
ISO
|
TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAK1 protein] Curcumin results in increased expression of BAK1 mRNA; Curcumin results in increased expression of BAK1 protein BAK1 protein results in increased susceptibility to Curcumin Curcumin results in decreased expression of BAK1 mRNA
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CTD |
PMID:17277231 PMID:17332930 PMID:18226269 PMID:33582110 |
|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
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|
| G
|
Bax
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BCL2 associated X, apoptosis regulator
|
multiple interactions affects expression decreases expression increases expression affects localization increases response to substance
|
ISO EXP
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of BAX protein; [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of BAX protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of BAX protein; [Curcumin co-treated with Quercetin] results in increased expression of BAX protein; [Curcumin co-treated with Sirolimus] results in increased expression of BAX; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; Arsenic Trioxide promotes the reaction [Curcumin affects the localization of BAX protein]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of BAX protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of BAX protein]; Curcumin promotes the reaction [Arsenic Trioxide affects the localization of BAX protein]; Curcumin promotes the reaction [lonidamine affects the localization of BAX protein]; Curcumin promotes the reaction [Paclitaxel promotes the reaction [Calcitriol results in increased expression of BAX protein]]; Curcumin promotes the reaction [Paclitaxel results in increased expression of BAX protein]; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; lonidamine promotes the reaction [Curcumin affects the localization of BAX protein]; Paclitaxel promotes the reaction [Curcumin results in increased expression of BAX protein]; piperine inhibits the reaction [Curcumin results in decreased expression of BAX protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of BAX protein] Curcumin affects the expression of BAX protein Curcumin results in decreased expression of BAX mRNA; Curcumin results in decreased expression of BAX protein Curcumin results in increased expression of BAX mRNA; Curcumin results in increased expression of BAX protein 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased expression of BAX mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased expression of BAX protein]; [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased expression of BAX mRNA]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of BAX protein]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Gentamicins results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of BAX protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] BAX protein results in increased susceptibility to Curcumin [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased expression of BAX protein]; Curcumin affects the localization of and results in increased expression of and results in increased activity of BAX protein; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BAX protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]
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CTD |
PMID:15569404 PMID:17096185 PMID:17277231 PMID:17332930 PMID:17531121 PMID:17671742 PMID:18226269 PMID:19235267 PMID:19373661 PMID:20605902 PMID:20869986 PMID:21594647 PMID:23222814 PMID:23267840 PMID:24952339 PMID:25541178 PMID:25963729 PMID:26612707 PMID:27132804 PMID:27288928 PMID:27430728 PMID:27793699 PMID:27966075 PMID:28681665 PMID:30463061 PMID:30935902 PMID:31628941 PMID:33582110 PMID:34577062 PMID:35817260 PMID:36037877 PMID:36178099 PMID:36305173 PMID:36352148 PMID:38056816 PMID:38348716 More...
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|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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| G
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Bbc3
|
Bcl-2 binding component 3
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
Curcumin results in increased expression of BBC3 mRNA Curcumin results in decreased expression of BBC3 mRNA Curcumin inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]
|
CTD |
PMID:17332930 PMID:22714040 PMID:34047412 |
|
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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|
| G
|
Bcl10
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BCL10, immune signaling adaptor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL10 mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829
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|
| G
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Bcl2
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BCL2, apoptosis regulator
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Arsenic Trioxide co-treated with Curcumin] affects the expression of BCL2 protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in decreased expression of BCL2 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Curcumin co-treated with Calcitriol] promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]; [Curcumin co-treated with Isoflavones] results in decreased expression of BCL2 protein; [Curcumin co-treated with Sirolimus] results in decreased expression of BCL2; [Curcumin results in increased expression of SERPINB5] which results in decreased expression of BCL2 protein; [Dihydrotestosterone co-treated with Curcumin co-treated with Quercetin] results in increased expression of BCL2 protein; [piperine co-treated with Curcumin] results in decreased expression of BCL2 protein; [Vitamin E co-treated with Curcumin] results in decreased expression of BCL2 protein; Curcumin inhibits the reaction [Docetaxel results in increased phosphorylation of BCL2 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; Curcumin promotes the reaction [Calcitriol promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]]; Curcumin promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]; Curcumin promotes the reaction [sodium arsenite results in decreased expression of BCL2 protein]; Curcumin results in increased ubiquitination of and results in increased degradation of BCL2 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Curcumin results in increased ubiquitination of and results in increased degradation of BCL2 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of BCL2 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2 protein] Curcumin results in increased expression of BCL2 mRNA; Curcumin results in increased expression of BCL2 protein Curcumin results in decreased expression of BCL2 mRNA; Curcumin results in decreased expression of BCL2 protein Curcumin analog results in decreased expression of BCL2 mRNA; Curcumin results in decreased expression of BCL2 mRNA; Curcumin results in decreased expression of BCL2 protein [Curcumin co-treated with Gemcitabine] results in decreased expression of BCL2 protein; [Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of BCL2 protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of BCL2 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of BCL2 protein]; [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in decreased expression of BCL2 mRNA]; carboxymethyl-chitosan analog promotes the reaction [Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin results in increased expression of BCL2 protein]; Curcumin affects the reaction [Ketamine results in decreased expression of BCL2 protein]; Curcumin analog inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Cyclosporine results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Gentamicins results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein]; Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]
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CTD |
PMID:12497104 PMID:14724571 PMID:15569404 PMID:16023083 PMID:16219905 PMID:16243823 PMID:17096185 PMID:17332930 PMID:17440100 PMID:17531121 PMID:17596214 PMID:17640567 PMID:17671737 PMID:17671742 PMID:18226269 PMID:18593936 PMID:18640131 PMID:18829502 PMID:19235267 PMID:19250217 PMID:19372569 PMID:19373661 PMID:19944674 PMID:20127174 PMID:20727180 PMID:20869986 PMID:21397623 PMID:21594647 PMID:21595920 PMID:21793155 PMID:22714040 PMID:23452621 PMID:24952339 PMID:25256401 PMID:25541178 PMID:25963729 PMID:26409325 PMID:26612707 PMID:27132804 PMID:27288928 PMID:27430728 PMID:28681665 PMID:29571711 PMID:30138604 PMID:30431687 PMID:30935902 PMID:31628941 PMID:32569592 PMID:33582110 PMID:33617879 PMID:34577062 PMID:34675983 PMID:34758851 PMID:35817260 PMID:36037877 PMID:36178099 PMID:36305173 PMID:36352148 PMID:38056816 PMID:38348716 More...
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|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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|
| G
|
Bcl2a1
|
BCL2-related protein A1
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2A1 mRNA] Curcumin results in decreased expression of BCL2A1 mRNA
|
CTD |
PMID:16219905 PMID:17596214 |
|
NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
|
|
| G
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Bcl2l1
|
Bcl2-like 1
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
[Curcumin co-treated with Doxorubicin] affects the expression of BCL2L1 mRNA; [Curcumin co-treated with Isoflavones] results in decreased expression of BCL2L1 protein; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2L1 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL2L1 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BCL2L1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2L1 protein] Curcumin analog results in decreased expression of BCL2L1 mRNA; Curcumin results in decreased expression of BCL2L1 mRNA; Curcumin results in decreased expression of BCL2L1 protein Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2L1 protein] [Curcumin co-treated with Gemcitabine] results in decreased expression of BCL2L1 protein Curcumin results in increased expression of BCL2L1 mRNA
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CTD |
PMID:12497104 PMID:15569404 PMID:15911101 PMID:16023083 PMID:16173963 PMID:16219905 PMID:16243823 PMID:17148446 PMID:17332930 PMID:17440100 PMID:17596214 PMID:17640567 PMID:17671737 PMID:18226269 PMID:18640131 PMID:18829502 PMID:19235267 PMID:19250217 PMID:19372569 PMID:23452621 PMID:30463061 More...
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|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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|
| G
|
Bcl2l11
|
Bcl2-like 11
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of BCL2L11 mRNA [arsenic trioxide co-treated with Curcumin] results in increased expression of BCL2L11 protein
|
CTD |
PMID:17332930 PMID:27430728 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
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|
| G
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Bcl2l2
|
Bcl2-like 2
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of BCL2L2 mRNA [arsenic trioxide co-treated with Curcumin] affects the expression of BCL2L2 protein
|
CTD |
PMID:16101141 PMID:27430728 |
|
NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379
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|
| G
|
Bcl3
|
BCL3, transcription coactivator
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL3 mRNA] Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA]
|
CTD |
PMID:18200517 PMID:23452621 |
|
NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368
|
|
| G
|
Bcor
|
BCL6 co-repressor
|
increases expression
|
ISO
|
Curcumin results in increased expression of BCOR mRNA
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CTD |
PMID:17198877 |
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NCBI chr X:13,282,431...13,402,254
Ensembl chr X:13,360,376...13,402,254
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| G
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Bdnf
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brain-derived neurotrophic factor
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multiple interactions increases expression affects expression
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EXP ISO
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[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BDNF protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of BDNF protein] Curcumin results in increased expression of BDNF protein Curcumin affects the expression of BDNF protein [Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of BDNF mRNA; Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BDNF protein]; Curcumin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]
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CTD |
PMID:17022948 PMID:17617388 PMID:17827730 PMID:19033880 PMID:22911773 PMID:27966075 PMID:29723552 PMID:32735850 PMID:34577062 More...
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NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
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| G
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Becn1
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beclin 1
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increases expression decreases expression multiple interactions
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ISO EXP
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Curcumin results in increased expression of BECN1 protein Curcumin results in decreased expression of BECN1 protein MIR206 affects the reaction [Curcumin results in increased expression of BECN1 protein]
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CTD |
PMID:34634291 PMID:36640941 PMID:38764151 |
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NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
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| G
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Bgn
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biglycan
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA]
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CTD |
PMID:18200517 |
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NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799
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| G
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Bid
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BH3 interacting domain death agonist
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multiple interactions
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ISO
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[arsenic trioxide co-treated with Curcumin] results in decreased expression of BID protein; [arsenic trioxide co-treated with Curcumin] results in increased expression of BID protein; Curcumin promotes the reaction [arsenic trioxide results in increased activity of BID protein]
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CTD |
PMID:20605902 PMID:27430728 |
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NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
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| G
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Birc2
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baculoviral IAP repeat-containing 2
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decreases expression multiple interactions
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ISO
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Curcumin analog results in decreased expression of BIRC2 mRNA; Curcumin results in decreased expression of BIRC2 mRNA; Curcumin results in decreased expression of BIRC2 protein Curcumin inhibits the reaction [Nicotine results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]]
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CTD |
PMID:16023083 PMID:16219905 PMID:16243823 PMID:17596214 PMID:17640567 PMID:17671737 PMID:20727180 PMID:23452621 More...
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NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
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| G
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Birc3
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baculoviral IAP repeat-containing 3
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multiple interactions increases expression decreases expression
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ISO
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[arsenic trioxide co-treated with Curcumin] results in decreased expression of BIRC3 protein; [Curcumin co-treated with Doxorubicin] affects the expression of BIRC3 mRNA; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC3 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA] [Curcumin co-treated with Gemcitabine] results in decreased expression of BIRC3 protein Curcumin results in increased expression of BIRC3 mRNA Curcumin results in decreased expression of BIRC3 mRNA; Curcumin results in decreased expression of BIRC3 protein
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CTD |
PMID:15911101 PMID:16101141 PMID:16219905 PMID:16243823 PMID:17440100 PMID:17596214 PMID:19372569 PMID:27430728 More...
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NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
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| G
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Birc5
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baculoviral IAP repeat-containing 5
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multiple interactions decreases expression
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ISO EXP
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[Arsenic Trioxide co-treated with Curcumin] results in decreased expression of BIRC5 protein; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of BIRC5 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased expression of BIRC5 protein] Curcumin analog results in decreased expression of BIRC5 mRNA; Curcumin results in decreased expression of BIRC5 mRNA; Curcumin results in decreased expression of BIRC5 protein [Curcumin co-treated with Gemcitabine] results in decreased expression of BIRC5 protein Curcumin inhibits the reaction [Doxorubicin results in decreased expression of BIRC5 protein]
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CTD |
PMID:16023083 PMID:17440100 PMID:17596214 PMID:17671737 PMID:18593936 PMID:19235267 PMID:19372569 PMID:20727180 PMID:23452621 PMID:24664296 PMID:26409325 PMID:27430728 PMID:34047412 PMID:34233590 More...
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NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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| G
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Birc7
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baculoviral IAP repeat-containing 7
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increases expression multiple interactions
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ISO
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Curcumin results in increased expression of BIRC7 mRNA [arsenic trioxide co-treated with Curcumin] results in increased expression of BIRC7 protein
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CTD |
PMID:15911101 PMID:27430728 |
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NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:188,425,392...188,430,174
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| G
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Bmp2
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bone morphogenetic protein 2
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decreases expression
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ISO
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Curcumin results in decreased expression of BMP2 mRNA
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CTD |
PMID:27237783 |
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NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
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| G
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Brca1
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BRCA1, DNA repair associated
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Furazolidone results in increased expression of BRCA1 protein]
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CTD |
PMID:27996348 |
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NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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| G
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Bsg
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basigin
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decreases response to substance
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ISO
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BSG protein results in decreased susceptibility to Curcumin
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CTD |
PMID:18379992 |
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NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
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| G
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C1qa
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complement C1q A chain
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decreases expression
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ISO
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Curcumin results in decreased expression of C1QA mRNA
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CTD |
PMID:19555370 |
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NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
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| G
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C1qb
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complement C1q B chain
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA]
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CTD |
PMID:18200517 |
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NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
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| G
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C3
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complement C3
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA]
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CTD |
PMID:18200517 |
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NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
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| G
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C4b
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complement C4B
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA]
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CTD |
PMID:18200517 |
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NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289
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| G
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Ca9
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carbonic anhydrase 9
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decreases expression
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EXP
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Curcumin results in decreased expression of CAR9 mRNA
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CTD |
PMID:18299980 |
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NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626
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| G
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Camk2a
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calcium/calmodulin-dependent protein kinase II alpha
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multiple interactions
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ISO EXP
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[Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of CAMK2A mRNA Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CAMK2A protein]
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CTD |
PMID:22911773 PMID:29723552 |
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NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504
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| G
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Capg
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capping actin protein, gelsolin like
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA]
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CTD |
PMID:18200517 |
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NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672
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| G
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Casp1
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caspase 1
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increases expression multiple interactions
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ISO EXP
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Curcumin results in increased expression of CASP1 mRNA Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP1 mRNA] [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of CASP1 protein]; Curcumin inhibits the reaction [Atrazine results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of CASP1 protein] Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA]
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CTD |
PMID:16101141 PMID:23452621 PMID:34998855 PMID:35063475 PMID:38301994 PMID:38369055 More...
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NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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| G
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Casp12
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caspase 12
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increases expression multiple interactions
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ISO EXP
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Curcumin results in increased expression of CASP12 protein Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
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CTD |
PMID:21793155 PMID:25541178 |
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NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442
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| G
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Casp2
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caspase 2
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increases expression multiple interactions
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ISO EXP
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Curcumin results in increased expression of CASP2 mRNA Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP2 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP2 mRNA]
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CTD |
PMID:16101141 PMID:38369055 |
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NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022
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| G
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Casp3
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caspase 3
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multiple interactions decreases expression increases cleavage increases activity decreases activity increases expression
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ISO EXP
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[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP3 protein; [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in increased cleavage of CASP3 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of and results in increased cleavage of CASP3 protein; [Curcumin co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [Curcumin co-treated with lonidamine] results in increased cleavage of CASP3 protein; [Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein; [Curcumin co-treated with Sirolimus] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [quinocetone results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Curcumin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Curcumin results in increased cleavage of and results in increased activity of CASP3 protein; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; Glutathione inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; piperine inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased activity of CASP3 protein]] Curcumin results in decreased expression of CASP3 protein modified form Curcumin results in increased cleavage of CASP3 protein Curcumin results in decreased activity of CASP3 protein [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 mRNA]]; Curcumin analog inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Curcumin analog inhibits the reaction [Rotenone results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of and results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of and results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [bisphenol A results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Colistin results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Cyclosporine results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased cleavage of and results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein]; Curcumin results in decreased cleavage of and results in decreased activity of CASP3 protein [Curcumin co-treated with Gemcitabine] results in decreased expression of CASP3 protein; [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; [Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP3 protein; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of CASP3 protein modified form] Curcumin results in increased expression of CASP3 mRNA; Curcumin results in increased expression of CASP3 protein; Curcumin results in increased expression of CASP3 protein modified form Curcumin analog results in increased activity of CASP3 protein; Curcumin results in increased activity of CASP3; Curcumin results in increased activity of CASP3 protein Curcumin results in decreased expression of CASP3 mRNA; Curcumin results in decreased expression of CASP3 protein
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CTD |
PMID:15095415 PMID:15569404 PMID:16023083 PMID:16101141 PMID:17041101 PMID:17096185 PMID:17148446 PMID:17277231 PMID:17332930 PMID:17351913 PMID:17363495 PMID:17440100 PMID:17640567 PMID:17671742 PMID:17885582 PMID:18555241 PMID:19235267 PMID:19294764 PMID:19373661 PMID:19401701 PMID:20127174 PMID:20605902 PMID:20869986 PMID:21397623 PMID:21450334 PMID:21594647 PMID:21595920 PMID:22523229 PMID:23267840 PMID:23555722 PMID:23710286 PMID:24863870 PMID:24952339 PMID:25541178 PMID:25963729 PMID:26409325 PMID:26612707 PMID:27132804 PMID:27288928 PMID:27375190 PMID:27430728 PMID:27535828 PMID:27966075 PMID:28681665 PMID:29315967 PMID:29571711 PMID:30138604 PMID:30431687 PMID:30463061 PMID:30935902 PMID:31712109 PMID:31820278 PMID:32569592 PMID:33582110 PMID:33617879 PMID:33729022 PMID:34042043 PMID:34577062 PMID:34675983 PMID:34994998 PMID:35817260 PMID:36037877 PMID:36178099 PMID:36305173 PMID:37955270 PMID:38348716 PMID:38369055 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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| G
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Casp4
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caspase 4
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increases expression
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ISO
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Curcumin results in increased expression of CASP4 mRNA
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CTD |
PMID:16101141 |
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NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
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| G
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Casp7
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caspase 7
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multiple interactions increases expression decreases expression
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ISO EXP
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[Calcitriol co-treated with Curcumin] promotes the reaction [Paclitaxel results in increased expression of CASP7 protein]; [Curcumin co-treated with Sirolimus] results in increased activity of CASP7 protein; Calcitriol inhibits the reaction [Curcumin inhibits the reaction [Paclitaxel results in increased expression of CASP7 protein]]; Curcumin inhibits the reaction [Calcitriol inhibits the reaction [Paclitaxel results in increased expression of CASP7 protein]]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of CASP7 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP7 protein Curcumin results in increased expression of CASP7 protein Curcumin results in decreased expression of CASP7 mRNA Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP7 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP7 mRNA]
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CTD |
PMID:16023083 PMID:16101141 PMID:19373661 PMID:31628941 PMID:38369055 |
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NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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| G
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Casp8
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caspase 8
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increases activity multiple interactions increases cleavage decreases expression
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ISO EXP
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Curcumin results in increased activity of CASP8 protein Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP8 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA] Curcumin results in increased cleavage of CASP8 protein Curcumin results in decreased expression of CASP8 mRNA; Curcumin results in decreased expression of CASP8 protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP8 protein; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CASP8 mRNA]; Curcumin results in increased cleavage of and results in increased activity of CASP8 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Curcumin results in increased cleavage of CASP8 protein]
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CTD |
PMID:14555224 PMID:16173963 PMID:17096185 PMID:17148446 PMID:22523229 PMID:23267840 PMID:23452621 PMID:25541178 PMID:27430728 PMID:33582110 PMID:38369055 More...
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NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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| G
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Casp9
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caspase 9
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decreases expression multiple interactions increases activity increases expression increases cleavage
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ISO EXP
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Curcumin results in decreased expression of CASP9 mRNA; Curcumin results in decreased expression of CASP9 protein Curcumin inhibits the reaction [aristolochic acid I results in increased expression of and results in increased cleavage of CASP9 protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of CASP9 mRNA]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP9 mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased cleavage of and results in increased activity of CASP9 protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of CASP9 mRNA] Curcumin results in increased activity of CASP9 protein Curcumin results in increased expression of CASP9 protein [Curcumin co-treated with Gemcitabine] results in decreased expression of CASP9 protein; [Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP9 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP9 protein]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP9 protein Curcumin results in increased cleavage of CASP9 protein [Curcumin co-treated with Arsenic Trioxide] results in increased cleavage of CASP9 protein; [Curcumin co-treated with Calcitriol] promotes the reaction [Paclitaxel results in increased expression of CASP9 protein]; [Curcumin co-treated with lonidamine] results in increased cleavage of CASP9 protein; [Curcumin co-treated with Sirolimus] results in increased activity of CASP9 protein; [Paclitaxel co-treated with Calcitriol] promotes the reaction [Curcumin results in increased expression of CASP9 protein]; [Paclitaxel co-treated with Curcumin] promotes the reaction [Calcitriol results in increased expression of CASP9 protein]; Curcumin inhibits the reaction [quinocetone results in increased activity of CASP9 protein]; Curcumin promotes the reaction [[Calcitriol co-treated with Paclitaxel] results in increased expression of CASP9 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP9 protein; Paclitaxel promotes the reaction [Curcumin results in increased expression of CASP9 protein]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased activity of CASP9 protein]]
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CTD |
PMID:14555224 PMID:16023083 PMID:16101141 PMID:17148446 PMID:17277231 PMID:17440100 PMID:17671742 PMID:18555241 PMID:19095035 PMID:19373661 PMID:20605902 PMID:20869986 PMID:21594647 PMID:27375190 PMID:28681665 PMID:31628941 PMID:31712109 PMID:33582110 PMID:33729022 PMID:34994998 PMID:36037877 PMID:38369055 More...
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Ensembl chr 5:159,391,188...159,409,648
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| G
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Cat
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catalase
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multiple interactions increases expression increases activity
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ISO EXP
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[arsenite co-treated with Curcumin] results in increased expression of CAT protein; Curcumin inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of CAT protein]; Curcumin inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [quinocetone results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Vehicle Emissions promotes the reaction [Cisplatin results in decreased activity of CAT protein]]; Curcumin inhibits the reaction [Vehicle Emissions results in decreased activity of CAT protein] Curcumin results in increased expression of CAT mRNA Curcumin results in increased activity of CAT protein [Curcumin co-treated with alpha-Tocopherol] inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of CAT protein]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Curcumin analog inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin analog inhibits the reaction [Monocrotaline results in increased activity of CAT protein]; Curcumin analog inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased activity of CAT protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Acrylonitrile results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased activity of CAT protein]; Curcumin inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Chloroquine results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Colistin results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Fenitrothion results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [methylmercuric chloride results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Oxygen deficiency results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Sodium Selenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Tartrazine results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of CAT protein] Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Acrylamide results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Chloranil results in decreased activity of CAT protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Rotenone results in decreased activity of CAT protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CAT]; Curcumin metabolite inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; sodium arsenite inhibits the reaction [Curcumin results in increased activity of CAT protein] Curcumin results in increased expression of CAT protein
|
CTD |
PMID:16770732 PMID:17076682 PMID:17351913 PMID:17461496 PMID:18299980 PMID:18392098 PMID:19481068 PMID:19631675 PMID:19913070 PMID:19914224 PMID:20112103 PMID:20593964 PMID:21574897 PMID:21976817 PMID:22704994 PMID:24113306 PMID:24347089 PMID:24760747 PMID:25123790 PMID:25169090 PMID:25233897 PMID:25461551 PMID:27375190 PMID:28239801 PMID:28951138 PMID:29205955 PMID:29315967 PMID:30138604 PMID:30423402 PMID:30934151 PMID:30946834 PMID:31081568 PMID:31199764 PMID:31330227 PMID:31407471 PMID:31521693 PMID:31714633 PMID:31876186 PMID:32735850 PMID:33350580 PMID:34577062 PMID:34758851 PMID:34802538 PMID:35063475 PMID:35817260 PMID:36924976 More...
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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| G
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Cbr1
|
carbonyl reductase 1
|
multiple interactions
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ISO
|
[[Curcumin binds to and results in decreased activity of CBR1 protein] which results in decreased reduction of Daunorubicin] which results in decreased chemical synthesis of daunorubicinol; [Curcumin binds to and results in decreased activity of CBR1 protein] which results in decreased reduction of Daunorubicin; Curcumin binds to and results in decreased activity of CBR1 protein; Curcumin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; Curcumin inhibits the reaction [NADP metabolite binds to and results in increased activity of CBR1 protein]
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CTD |
PMID:25541467 |
|
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
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| G
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Ccar1
|
cell division cycle and apoptosis regulator 1
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increases expression
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ISO
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Curcumin results in increased expression of CCAR1 protein
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CTD |
PMID:21594647 |
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NCBI chr20:31,228,624...31,271,233
Ensembl chr20:31,228,624...31,271,227
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| G
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Ccdc116
|
coiled-coil domain containing 116
|
increases expression
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ISO
|
Curcumin results in increased expression of CCDC116 mRNA
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CTD |
PMID:18200517 |
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NCBI chr11:97,346,927...97,354,827
Ensembl chr11:97,346,675...97,354,824
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| G
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Ccl2
|
C-C motif chemokine ligand 2
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multiple interactions decreases expression increases expression
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ISO EXP
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Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]] Curcumin results in decreased expression of CCL2 mRNA; Curcumin results in decreased expression of CCL2 protein Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA] Curcumin results in increased expression of CCL2 mRNA
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CTD |
PMID:10925121 PMID:11053056 PMID:17198877 PMID:17666914 PMID:18403477 PMID:19152916 PMID:20712904 PMID:22683883 PMID:23452621 PMID:33952798 More...
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|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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| G
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Ccn2
|
cellular communication network factor 2
|
decreases expression multiple interactions
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ISO EXP
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Curcumin results in decreased expression of CCN2 mRNA; Curcumin results in decreased expression of CCN2 protein IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]; Lipopolysaccharides inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]; NFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]; PPARG protein promotes the reaction [Curcumin results in decreased expression of CCN2 mRNA]
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CTD |
PMID:17965732 PMID:19764552 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
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| G
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Ccna2
|
cyclin A2
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein] Curcumin results in decreased expression of CCNA2 protein
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CTD |
PMID:23222814 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
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|
| G
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Ccnb1
|
cyclin B1
|
decreases expression
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ISO
|
Curcumin results in decreased expression of CCNB1 mRNA; Curcumin results in decreased expression of CCNB1 protein
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CTD |
PMID:17148446 PMID:18719366 PMID:19401701 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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| G
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Ccnd1
|
cyclin D1
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increases expression multiple interactions decreases expression increases degradation
|
ISO EXP
|
Curcumin results in increased expression of CCND1 mRNA [Curcumin co-treated with Isoflavones] results in decreased expression of CCND1 protein; calyculin A inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]; Curcumin inhibits the reaction [Acrylamide results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Furazolidone results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [VIP protein results in increased expression of CCND1 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]]; lactacystin inhibits the reaction [Curcumin results in increased degradation of CCND1 protein]; piperine inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of CCND1 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CCND1 protein] Curcumin results in decreased expression of CCND1 mRNA; Curcumin results in decreased expression of CCND1 protein 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of CCND1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of CCND1 mRNA] Curcumin results in decreased expression of CCND1; Curcumin results in decreased expression of CCND1 protein [Curcumin co-treated with Gemcitabine] results in decreased expression of CCND1 protein Curcumin analog results in decreased expression of CCND1 protein; Curcumin results in decreased expression of CCND1 mRNA; Curcumin results in decreased expression of CCND1 protein
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CTD |
PMID:15486348 PMID:15489888 PMID:15738001 PMID:16023083 PMID:16219905 PMID:16243823 PMID:16959222 PMID:17041101 PMID:17148446 PMID:17440100 PMID:17531121 PMID:17602960 PMID:17640567 PMID:17885582 PMID:18156803 PMID:18226269 PMID:18316600 PMID:18593936 PMID:18640131 PMID:18790744 PMID:18829502 PMID:19189304 PMID:19372569 PMID:19501152 PMID:19573523 PMID:20727180 PMID:24211270 PMID:24508477 PMID:25822711 PMID:25963729 PMID:27996348 PMID:30935902 PMID:34233590 PMID:36640941 More...
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|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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| G
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Ccnd3
|
cyclin D3
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multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of CCND3 protein] Curcumin results in decreased expression of CCND3 protein
|
CTD |
PMID:23222814 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
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| G
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Ccne1
|
cyclin E1
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decreases expression multiple interactions increases degradation
|
ISO EXP
|
Curcumin results in decreased expression of CCNE1 protein Curcumin results in decreased expression of CCNE1 mRNA Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of CCNE1 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of CCNE1 protein]; lactacystin inhibits the reaction [Curcumin results in increased degradation of CCNE1 protein]
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CTD |
PMID:17148446 PMID:18156803 PMID:18299980 PMID:36640941 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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| G
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Ccpg1
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cell cycle progression 1
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increases expression
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ISO
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Curcumin results in increased expression of CCPG1 mRNA
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CTD |
PMID:17198877 |
|
NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:82,600,536...82,660,246
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|
| G
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Ccr2
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C-C motif chemokine receptor 2
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decreases expression
|
ISO
|
Curcumin results in decreased expression of CCR2 mRNA
|
CTD |
PMID:18403477 |
|
NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059
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|
| G
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Cd14
|
CD14 molecule
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multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]
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CTD |
PMID:18180316 |
|
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
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|
| G
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Cd36
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CD36 molecule
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decreases expression increases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of CD36 mRNA Curcumin results in increased expression of CD36 mRNA Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein] Curcumin results in decreased expression of CD36 mRNA; Curcumin results in decreased expression of CD36 protein
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CTD |
PMID:16713233 PMID:23386263 PMID:23603106 |
|
NCBI chr 4:18,209,088...18,302,142
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|
| G
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Cd40
|
CD40 molecule
|
decreases expression multiple interactions
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ISO EXP
|
Curcumin results in decreased expression of CD40 mRNA CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]]; CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] [arsenic trioxide co-treated with Curcumin] results in increased expression of CD40 protein
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CTD |
PMID:16101141 PMID:27430728 PMID:35549587 |
|
NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
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|
| G
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Cd40lg
|
CD40 ligand
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multiple interactions
|
ISO
|
[arsenic trioxide co-treated with Curcumin] results in increased expression of CD40LG protein
|
CTD |
PMID:27430728 |
|
NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475
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|
| G
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Cd44
|
CD44 molecule
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increases expression
|
ISO
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Curcumin results in increased expression of CD44 mRNA
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CTD |
PMID:15713895 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
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|
| G
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Cd47
|
Cd47 molecule
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272
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|
| G
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Cd55
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CD55 molecule (Cromer blood group)
|
decreases expression
|
ISO
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Curcumin results in decreased expression of CD55 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107
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|
| G
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Cdc14b
|
cell division cycle 14B
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increases expression
|
ISO
|
Curcumin results in increased expression of CDC14B mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr17:850,272...938,972
Ensembl chr17:850,390...971,164
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|
| G
|
Cdc20
|
cell division cycle 20
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decreases expression
|
ISO
|
Curcumin results in decreased expression of CDC20 mRNA
|
CTD |
PMID:22258452 |
|
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
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|
| G
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Cdc25c
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cell division cycle 25C
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increases phosphorylation
|
ISO
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Curcumin results in increased phosphorylation of CDC25C protein
|
CTD |
PMID:19401701 |
|
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
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|
| G
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Cdh1
|
cadherin 1
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increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of CDH1 protein Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of CDH1 mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of CDH1 protein] [Curcumin co-treated with Arsenic Trioxide] results in increased expression of CDH1 mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; Curcumin inhibits the reaction [Trichloroethylene results in decreased expression of CDH1 protein]
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CTD |
PMID:19573523 PMID:25656647 PMID:26191140 PMID:34233590 PMID:35487055 PMID:36640941 More...
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|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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|
| G
|
Cdh11
|
cadherin 11
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CDH11 protein
|
CTD |
PMID:18025290 |
|
NCBI chr19:2,152,961...2,312,140
Ensembl chr19:2,154,840...2,312,140
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|
| G
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Cdh17
|
cadherin 17
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CDH17 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226
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|
| G
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Cdh2
|
cadherin 2
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multiple interactions
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ISO EXP
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Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CDH2 mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CDH2 protein] Curcumin inhibits the reaction [Trichloroethylene results in increased expression of CDH2 protein] Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CDH2 protein]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CDH2 protein]]
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CTD |
PMID:26191140 PMID:34233590 PMID:35549587 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
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|
| G
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Cdk1
|
cyclin-dependent kinase 1
|
decreases expression
|
EXP ISO
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Curcumin results in decreased expression of CDK1 mRNA Curcumin results in decreased expression of CDK1 mRNA; Curcumin results in decreased expression of CDK1 protein
|
CTD |
PMID:17148446 PMID:18299980 PMID:19401701 PMID:22258452 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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|
| G
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Cdk2
|
cyclin dependent kinase 2
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of CDK2 protein] Curcumin inhibits the reaction [Atrazine results in decreased expression of CDK2 mRNA]; Curcumin inhibits the reaction [Atrazine results in decreased expression of CDK2 protein] Curcumin results in decreased expression of CDK2 protein Curcumin analog results in decreased expression of CDK2 mRNA; Curcumin results in decreased expression of CDK2 protein
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CTD |
PMID:19501152 PMID:23222814 PMID:26409325 PMID:38301994 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
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|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of CDK4 mRNA; Curcumin results in decreased expression of CDK4 protein
|
CTD |
PMID:18156803 PMID:24211270 PMID:26409325 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
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|
| G
|
Cdk5
|
cyclin-dependent kinase 5
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of CDK5 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777
|
|
| G
|
Cdk6
|
cyclin-dependent kinase 6
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CDK6 protein
|
CTD |
PMID:18156803 |
|
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701
|
|
| G
|
Cdk7
|
cyclin-dependent kinase 7
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of CDK7 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485
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|
| G
|
Cdk9
|
cyclin-dependent kinase 9
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of CDK9 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:36,394,169...36,399,528
|
|
| G
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Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1A protein; [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CDKN1A mRNA; [Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein; [piperine co-treated with Curcumin] results in decreased expression of CDKN1A protein; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein]; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; EGR1 protein affects the reaction [Curcumin results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [Curcumin results in increased expression of CDKN1A mRNA]; MAPK1 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]; MAPK8 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1A protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CDKN1A protein] [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein]; Curcumin inhibits the reaction [Atrazine results in increased expression of CDKN1A mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of CDKN1A protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein] Curcumin results in increased expression of CDKN1A; Curcumin results in increased expression of CDKN1A mRNA; Curcumin results in increased expression of CDKN1A protein [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA; Curcumin results in decreased expression of CDKN1A protein Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of CDKN1A protein]
|
CTD |
PMID:15713895 PMID:15738001 PMID:17148446 PMID:17332326 PMID:17602960 PMID:18156803 PMID:18161303 PMID:18226269 PMID:18316600 PMID:18593936 PMID:20153625 PMID:23222814 PMID:25644192 PMID:25822711 PMID:27132804 PMID:27430728 PMID:28681665 PMID:30935902 PMID:33582110 PMID:38301994 More...
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|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Curcumin results in increased expression of CDKN1B mRNA; Curcumin results in increased expression of CDKN1B protein Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of CDKN1B protein] [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1B protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of CDKN1B protein; [Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1B protein] Curcumin results in decreased expression of CDKN1B protein
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CTD |
PMID:15713895 PMID:17602960 PMID:18156803 PMID:18226269 PMID:18593936 PMID:21594647 PMID:25822711 PMID:27132804 PMID:27430728 PMID:36352148 More...
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|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
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| G
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Cdkn2a
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cyclin-dependent kinase inhibitor 2A
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decreases expression increases expression
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ISO
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Curcumin results in decreased expression of CDKN2A protein Curcumin results in increased expression of CDKN2A protein
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CTD |
PMID:17148446 PMID:18156803 |
|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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| G
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Cdkn2d
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cyclin dependent kinase inhibitor 2D
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decreases expression
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EXP
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Curcumin results in decreased expression of CDKN2D mRNA
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CTD |
PMID:18299980 |
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NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809
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| G
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Cdx2
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caudal type homeo box 2
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increases expression
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EXP ISO
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Curcumin results in increased expression of CDX2 mRNA
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CTD |
PMID:18299980 PMID:27237783 |
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NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246
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| G
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Cebpa
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CCAAT/enhancer binding protein alpha
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multiple interactions
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ISO
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Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]; Curcumin inhibits the reaction [Dietary Fats results in increased expression of CEBPA mRNA]
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CTD |
PMID:19297423 PMID:28595985 |
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NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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| G
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Cebpb
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CCAAT/enhancer binding protein beta
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA]
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CTD |
PMID:18200517 |
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NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
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| G
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Ces1d
|
carboxylesterase 1D
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA]
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CTD |
PMID:18200517 |
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NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
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| G
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Ces3a
|
carboxylesterase 3a
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA]
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CTD |
PMID:18200517 |
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NCBI chr19:49,902,312...49,910,484
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|
| G
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Cflar
|
CASP8 and FADD-like apoptosis regulator
|
multiple interactions decreases expression
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ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CFLAR mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA] Curcumin results in decreased expression of CFLAR protein
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CTD |
PMID:16173963 PMID:16219905 PMID:23452621 |
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NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
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|
| G
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Cftr
|
CF transmembrane conductance regulator
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multiple interactions increases activity affects localization
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ISO
|
[PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein]; Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]; Curcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid] Curcumin results in increased activity of CFTR protein; Curcumin results in increased activity of CFTR protein mutant form Curcumin affects the localization of CFTR protein mutant form Curcumin affects the folding of and affects the localization of CFTR protein mutant form
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CTD |
PMID:15105504 PMID:15280357 PMID:15582996 PMID:17178710 PMID:23978416 |
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NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
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| G
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Chat
|
choline O-acetyltransferase
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multiple interactions
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EXP
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Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CHAT protein]
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CTD |
PMID:21839772 |
|
NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416
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| G
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Chek1
|
checkpoint kinase 1
|
decreases response to substance increases activity increases phosphorylation multiple interactions
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ISO
|
CHEK1 protein results in decreased susceptibility to Curcumin Curcumin results in increased activity of CHEK1 protein Curcumin results in increased phosphorylation of CHEK1 protein Curcumin inhibits the reaction [Furazolidone results in increased expression of CHEK1 protein]
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CTD |
PMID:18602917 PMID:19401701 PMID:27996348 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
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| G
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Chek2
|
checkpoint kinase 2
|
multiple interactions increases phosphorylation
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ISO
|
[Curcumin co-treated with Dihydrotestosterone] results in increased phosphorylation of CHEK2 protein; [Curcumin co-treated with Metribolone] results in increased phosphorylation of CHEK2 protein; [Isoflavones co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein; Flutamide inhibits the reaction [[Dihydrotestosterone co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein] Curcumin results in increased phosphorylation of CHEK2 protein
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CTD |
PMID:21134073 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
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|
| G
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Chrm2
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cholinergic receptor, muscarinic 2
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multiple interactions
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EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CHRM2 mRNA]
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CTD |
PMID:24952339 |
|
NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464
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| G
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Chuk
|
component of inhibitor of nuclear factor kappa B kinase complex
|
multiple interactions decreases activity
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ISO
|
Curcumin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Curcumin inhibits the reaction [TNFSF11 protein results in increased activity of CHUK protein] Curcumin results in decreased activity of CHUK protein
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CTD |
PMID:15129424 PMID:15489888 PMID:16023083 PMID:16219905 |
|
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
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| G
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Ckb
|
creatine kinase B
|
multiple interactions
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EXP
|
Curcumin inhibits the reaction [Doxorubicin results in increased expression of [CKM protein binds to CKB protein]]; Curcumin inhibits the reaction [lead acetate results in increased secretion of [CKM protein binds to CKB protein]]
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CTD |
PMID:21378372 PMID:29315967 |
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NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
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|
| G
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Ckm
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creatine kinase, M-type
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multiple interactions
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EXP
|
Curcumin inhibits the reaction [Doxorubicin results in increased expression of [CKM protein binds to CKB protein]]; Curcumin inhibits the reaction [Gentamicins results in increased secretion of CKM protein]; Curcumin inhibits the reaction [lead acetate results in increased secretion of [CKM protein binds to CKB protein]]
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CTD |
PMID:21378372 PMID:29315967 PMID:38056816 |
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NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
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| G
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Clca4
|
chloride channel accessory 4
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:236,544,201...236,563,435
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| G
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Clcn6
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chloride voltage-gated channel 6
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decreases expression
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ISO
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Curcumin results in decreased expression of CLCN6 mRNA
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CTD |
PMID:17198877 |
|
NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:163,717,439...163,748,198
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|
| G
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Cldn1
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claudin 1
|
multiple interactions
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ISO
|
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]
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CTD |
PMID:35817260 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
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|
| G
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Cldn2
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claudin 2
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multiple interactions
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EXP
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Curcumin inhibits the reaction [maleic acid results in decreased expression of CLDN2]
|
CTD |
PMID:25119790 |
|
NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377
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|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions decreases expression
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EXP ISO
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Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]] Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA] Curcumin results in decreased expression of COL1A1 mRNA; Curcumin results in decreased expression of COL1A1 protein
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CTD |
PMID:17355460 PMID:17434272 PMID:17531121 PMID:17602960 PMID:17965732 PMID:18006644 PMID:28700904 PMID:32718261 More...
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|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
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|
| G
|
Col1a2
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collagen type I alpha 2 chain
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
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|
| G
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Col27a1
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collagen type XXVII alpha 1 chain
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increases expression
|
EXP
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Curcumin results in increased expression of COL27A1 mRNA
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CTD |
PMID:18299980 |
|
NCBI chr 5:81,662,822...81,781,502
Ensembl chr 5:81,661,685...81,781,502
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|
| G
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Col2a1
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collagen type II alpha 1 chain
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increases expression multiple interactions
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ISO
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Curcumin results in increased expression of COL2A1 mRNA; Curcumin results in increased expression of COL2A1 protein [resveratrol co-treated with Curcumin] results in increased expression of COL2A1 protein
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CTD |
PMID:18321735 PMID:19889203 |
|
NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
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|
| G
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Col3a1
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collagen type III alpha 1 chain
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multiple interactions
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EXP
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Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]
|
CTD |
PMID:22683883 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
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|
| G
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Col4a1
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collagen type IV alpha 1 chain
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increases expression multiple interactions
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ISO EXP
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Curcumin results in increased expression of COL4A1 mRNA Curcumin analog inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA]
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CTD |
PMID:18200517 PMID:21594647 PMID:28700904 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
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|
| G
|
Col4a2
|
collagen type IV alpha 2 chain
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520
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|
| G
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Col4a5
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collagen type IV alpha 5 chain
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decreases expression
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ISO
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Curcumin results in decreased expression of COL4A5 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr X:109,907,251...110,111,214
Ensembl chr X:109,907,346...110,111,214
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|
| G
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Col5a1
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collagen type V alpha 1 chain
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020
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|
| G
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Col5a2
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collagen type V alpha 2 chain
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150
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|
| G
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Cpt1a
|
carnitine palmitoyltransferase 1A
|
increases expression
|
ISO
|
Curcumin results in increased expression of CPT1A mRNA
|
CTD |
PMID:19297423 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
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|
| G
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Creb1
|
cAMP responsive element binding protein 1
|
increases expression multiple interactions increases phosphorylation
|
EXP ISO
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Curcumin results in increased expression of CREB1 mRNA [Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of CREB1 mRNA; Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREB1 protein] Curcumin results in increased phosphorylation of CREB1 protein 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CREB1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CREB1 protein]]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CREB1 protein]
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CTD |
PMID:17022948 PMID:18299980 PMID:22911773 PMID:27966075 PMID:29723552 PMID:32735850 More...
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NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
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|
| G
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Creb3
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cAMP responsive element binding protein 3
|
increases expression
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EXP
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Curcumin results in increased expression of CREB3 mRNA
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CTD |
PMID:18299980 |
|
NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:62,613,638...62,619,500
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| G
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Crebbp
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CREB binding protein
|
multiple interactions
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ISO
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Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]]
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CTD |
PMID:22258452 |
|
NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266
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|
| G
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Crp
|
C-reactive protein
|
multiple interactions
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EXP ISO
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Curcumin analog inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein]; Curcumin inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein]; Curcumin inhibits the reaction [Fructose results in increased expression of CRP protein]; Curcumin inhibits the reaction [lead acetate results in increased secretion of CRP protein] [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of CRP protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of CRP protein]
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CTD |
PMID:21378372 PMID:26713546 PMID:30431687 PMID:31820278 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
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|
| G
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Cryab
|
crystallin, alpha B
|
multiple interactions
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ISO EXP
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Curcumin promotes the reaction [arsenite results in increased expression of CRYAB protein] [Curcumin co-treated with arsenite] results in increased expression of CRYAB mRNA; [Curcumin co-treated with Cadmium Chloride] results in increased expression of CRYAB protein; Curcumin promotes the reaction [arsenite results in increased expression of CRYAB protein]
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CTD |
PMID:9764755 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
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|
| G
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Cs
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citrate synthase
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affects expression
|
EXP
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Curcumin affects the expression of CS mRNA
|
CTD |
PMID:18539377 |
|
NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938
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|
| G
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Csf1
|
colony stimulating factor 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [CSF1 protein results in increased phosphorylation of CSF1R protein]
|
CTD |
PMID:15129424 |
|
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
|
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| G
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Csf1r
|
colony stimulating factor 1 receptor
|
multiple interactions increases expression
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ISO
|
Curcumin inhibits the reaction [CSF1 protein results in increased phosphorylation of CSF1R protein] Curcumin results in increased expression of CSF1R mRNA
|
CTD |
PMID:15129424 PMID:22714040 |
|
NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806
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|
| G
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Csf2ra
|
colony stimulating factor 2 receptor subunit alpha
|
increases expression
|
ISO
|
Curcumin results in increased expression of CSF2RA mRNA
|
CTD |
PMID:22714040 |
|
NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117
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|
| G
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Csf2rb
|
colony stimulating factor 2 receptor subunit beta
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654
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|
| G
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Ctnnb1
|
catenin beta 1
|
decreases phosphorylation increases expression multiple interactions decreases expression increases degradation
|
EXP ISO
|
Curcumin results in decreased phosphorylation of CTNNB1 protein Curcumin results in increased expression of CTNNB1 mRNA Curcumin inhibits the reaction [bisphenol A results in decreased expression of CTNNB1 mRNA]; Curcumin results in decreased phosphorylation of and affects the localization of CTNNB1 protein Curcumin analog results in decreased expression of CTNNB1 mRNA; Curcumin results in decreased expression of CTNNB1 mRNA; Curcumin results in decreased expression of CTNNB1 protein [piperine co-treated with Curcumin] results in decreased expression of CTNNB1 protein; Curcumin inhibits the reaction [CTNNB1 protein binds to TCF7L2 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CTNNB1 protein]; Curcumin results in decreased activity of [CTNNB1 protein binds to TCF7L2 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CTNNB1 protein] Curcumin analog results in increased degradation of CTNNB1 protein; Curcumin results in increased degradation of CTNNB1 protein
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CTD |
PMID:10783313 PMID:17041101 PMID:19294764 PMID:19573523 PMID:25963729 PMID:27645308 PMID:30935902 More...
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|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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|
| G
|
Ctsb
|
cathepsin B
|
multiple interactions decreases expression
|
EXP ISO
|
Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein] Curcumin analog results in decreased expression of CTSB mRNA
|
CTD |
PMID:8534267 PMID:26409325 |
|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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|
| G
|
Ctsd
|
cathepsin D
|
multiple interactions decreases expression
|
EXP ISO
|
Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] Curcumin analog results in decreased expression of CTSD mRNA
|
CTD |
PMID:8534267 PMID:26409325 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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|
| G
|
Ctsl
|
cathepsin L
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CTSL protein
|
CTD |
PMID:34138966 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
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|
| G
|
Ctss
|
cathepsin S
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CTSS mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
|
|
| G
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Cul3
|
cullin 3
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of CUL3 mRNA]
|
CTD |
PMID:38272317 |
|
NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:89,040,987...89,118,427
|
|
| G
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Cxcl1
|
C-X-C motif chemokine ligand 1
|
multiple interactions decreases expression
|
ISO
|
NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA] Curcumin results in decreased expression of CXCL1 mRNA; Curcumin results in decreased expression of CXCL1 protein
|
CTD |
PMID:17999991 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
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Cxcl12
|
C-X-C motif chemokine ligand 12
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA]; Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]
|
CTD |
PMID:18660423 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcl14
|
C-X-C motif chemokine ligand 14
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CXCL14 mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
decreases expression multiple interactions
|
ISO EXP
|
Curcumin results in decreased expression of CXCL2 mRNA; Curcumin results in decreased expression of CXCL2 protein Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA] Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased secretion of CXCL2 protein] NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL2 mRNA]
|
CTD |
PMID:17999991 PMID:18001810 PMID:18200517 PMID:27194111 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of CXCL1 mRNA; Curcumin results in decreased expression of CXCL1 protein NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA] Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]
|
CTD |
PMID:17999991 PMID:27194111 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcr1
|
C-X-C motif chemokine receptor 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of CXCR1 protein
|
CTD |
PMID:12216086 |
|
NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872
|
|
| G
|
Cxcr2
|
C-X-C motif chemokine receptor 2
|
increases expression
|
ISO
|
Curcumin results in increased expression of CXCR2 protein
|
CTD |
PMID:12216086 |
|
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of CXCR4 mRNA Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA]
|
CTD |
PMID:17198877 PMID:18660423 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cycs
|
cytochrome c, somatic
|
affects localization multiple interactions
|
ISO
|
Curcumin affects the localization of CYCS protein [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CYCS protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in increased expression of CYCS protein
|
CTD |
PMID:19235267 PMID:27430728 PMID:33617879 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
|
|
| G
|
Cym
|
chymosin
|
increases expression
|
EXP
|
Curcumin results in increased expression of CYM mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 2:197,516,947...197,527,307
Ensembl chr 2:197,516,950...197,527,837
|
|
| G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
affects binding
|
EXP
|
Curcumin binds to CYP19A1 protein
|
CTD |
PMID:39746524 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions increases activity increases expression decreases activity decreases expression
|
ISO EXP
|
Acetylcysteine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Buthionine Sulfoximine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; Curcumin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]; decitabine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]; trichostatin A affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]] Curcumin inhibits the reaction [Aflatoxin B1 results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Fenitrothion results in increased expression of CYP1A1 mRNA] Curcumin results in increased activity of CYP1A1 protein Curcumin results in increased expression of CYP1A1 mRNA Curcumin results in decreased activity of CYP1A1 protein Curcumin results in decreased expression of CYP1A1 mRNA Curcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:11454723 PMID:12628514 PMID:15841493 PMID:16288784 PMID:17012224 PMID:17880909 PMID:18321868 PMID:19018768 PMID:20015472 PMID:20816778 PMID:22867086 PMID:27041069 PMID:34802538 More...
|
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases activity multiple interactions
|
ISO EXP
|
Curcumin results in decreased activity of CYP1A2 protein Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A2 protein]; Curcumin inhibits the reaction [Fenitrothion results in increased expression of CYP1A2 mRNA] Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CYP1A2 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]
|
CTD |
PMID:15841493 PMID:16288784 PMID:18321868 PMID:34802538 PMID:35063475 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] Curcumin results in decreased expression of CYP1B1 mRNA
|
CTD |
PMID:17637178 PMID:19018768 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
|
|
| G
|
Cyp24a1
|
cytochrome P450, family 24, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
ISO
|
[Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA Curcumin results in increased expression of CYP24A1 protein
|
CTD |
PMID:20153625 |
|
NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083
|
|
| G
|
Cyp2b1
|
cytochrome P450, family 2, subfamily b, polypeptide 1
|
affects expression multiple interactions
|
EXP
|
Curcumin affects the expression of CYP2B1 protein Curcumin inhibits the reaction [CYP2B1 protein results in increased metabolism of nitrosobenzylmethylamine]
|
CTD |
PMID:16805852 |
|
NCBI chr 1:90,646,098...90,669,762
|
|
| G
|
Cyp2c7
|
cytochrome P450, family 2, subfamily c, polypeptide 7
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2C9 protein]
|
CTD |
PMID:16288784 |
|
NCBI chr 1:247,966,295...248,022,393
Ensembl chr 1:247,966,346...248,022,388
|
|
| G
|
Cyp2d4
|
cytochrome P450, family 2, subfamily d, polypeptide 4
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of CYP2D6 mRNA
|
CTD |
PMID:33582110 |
|
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
|
|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
affects expression multiple interactions increases expression
|
EXP ISO
|
Curcumin affects the expression of CYP2E1 protein Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]; Curcumin metabolite inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Curcumin metabolite inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]; Curcumin metabolite promotes the reaction [Acetaminophen results in decreased activity of CYP2E1 protein] Curcumin inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein] Curcumin results in increased expression of CYP2E1 mRNA
|
CTD |
PMID:16805852 PMID:18539377 PMID:24508477 PMID:30423402 PMID:33350580 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
decreases expression multiple interactions increases expression
|
ISO
|
Curcumin results in decreased expression of CYP3A4 mRNA [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA; Curcumin inhibits the reaction [Calcitriol results in increased expression of and results in increased activity of CYP3A4 protein]; Curcumin inhibits the reaction [Calcitriol results in increased expression of CYP3A4 mRNA]; Curcumin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam] Curcumin results in increased expression of CYP3A4 mRNA
|
CTD |
PMID:17210444 PMID:17270371 PMID:17965521 PMID:18385293 PMID:20153625 PMID:20816778 More...
|
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Cyp4a3
|
cytochrome P450, family 4, subfamily a, polypeptide 3
|
increases expression
|
EXP
|
Curcumin results in increased expression of CYP4A3 mRNA
|
CTD |
PMID:18539377 |
|
NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236
|
|
| G
|
Cyth4
|
cytohesin 4
|
increases expression
|
ISO
|
Curcumin results in increased expression of CYTH4 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 7:112,032,711...112,057,204
Ensembl chr 7:112,032,775...112,057,204
|
|
| G
|
Daxx
|
death-domain associated protein
|
increases expression
|
ISO
|
Curcumin results in increased expression of DAXX mRNA
|
CTD |
PMID:16101141 |
|
NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720
|
|
| G
|
Dbn1
|
drebrin 1
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Glucose results in decreased expression of DBN1 mRNA]
|
CTD |
PMID:23333261 |
|
NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122
|
|
| G
|
Dcn
|
decorin
|
increases expression
|
ISO
|
Curcumin results in increased expression of DCN mRNA
|
CTD |
PMID:21594647 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
|
|
| G
|
Dcx
|
doublecortin
|
multiple interactions increases expression
|
EXP ISO
|
Curcumin inhibits the reaction [bisphenol A results in decreased expression of DCX mRNA] Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCX protein] Curcumin results in increased expression of DCX mRNA
|
CTD |
PMID:25963729 PMID:32735850 |
|
NCBI chr X:112,227,455...112,370,291
Ensembl chr X:112,227,455...112,304,161
|
|
| G
|
Ddit3
|
DNA-damage inducible transcript 3
|
multiple interactions increases expression
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased expression of DDIT3 protein]; Curcumin inhibits the reaction [Furazolidone results in increased expression of DDIT3 protein]; Glutathione inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Glutathione inhibits the reaction [Curcumin results in increased expression of DDIT3 protein]; PRKCD protein promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA]; rottlerin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 protein] Curcumin results in increased expression of DDIT3 mRNA; Curcumin results in increased expression of DDIT3 protein
|
CTD |
PMID:16613838 PMID:17171638 PMID:18200517 PMID:18719366 PMID:21793155 PMID:27996348 PMID:29723631 More...
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|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
|
|
| G
|
Ddit4l
|
DNA-damage-inducible transcript 4-like
|
decreases expression increases expression
|
ISO EXP
|
Curcumin results in decreased expression of DDIT4L mRNA Curcumin results in increased expression of DDIT4L mRNA
|
CTD |
PMID:17999991 PMID:18299980 |
|
NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
|
|
| G
|
Derl1
|
derlin 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of DERL1 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678
|
|
| G
|
Des
|
desmin
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Gentamicins results in increased expression of DES mRNA]
|
CTD |
PMID:38056816 |
|
NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347
|
|
| G
|
Dffb
|
DNA fragmentation factor subunit beta
|
increases expression decreases expression
|
ISO
|
Curcumin results in increased expression of DFFB mRNA; Curcumin results in increased expression of DFFB protein Curcumin results in decreased expression of DFFB protein
|
CTD |
PMID:21397623 PMID:22714040 |
|
NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225
|
|
| G
|
Dhcr24
|
24-dehydrocholesterol reductase
|
decreases expression affects expression
|
EXP ISO
|
Curcumin results in decreased expression of DHCR24 mRNA Curcumin affects the expression of DHCR24 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
|
|
| G
|
Dhcr7
|
7-dehydrocholesterol reductase
|
affects expression decreases expression
|
ISO EXP
|
Curcumin affects the expression of DHCR7 mRNA Curcumin results in decreased expression of DHCR7 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382
|
|
| G
|
Dhrs1
|
dehydrogenase/reductase 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of DHRS1 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr15:33,206,449...33,213,776
Ensembl chr15:33,206,451...33,213,734
|
|
| G
|
Diablo
|
diablo, IAP-binding mitochondrial protein
|
multiple interactions affects localization increases expression increases response to substance
|
ISO
|
[arsenic trioxide co-treated with Curcumin] results in increased expression of DIABLO protein Curcumin affects the localization of DIABLO protein Curcumin results in increased expression of DIABLO mRNA DIABLO protein results in increased susceptibility to Curcumin
|
CTD |
PMID:17277231 PMID:23555722 PMID:27430728 |
|
NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
|
|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
decreases expression multiple interactions
|
EXP
|
Curcumin results in decreased expression of DKK1 mRNA; Curcumin results in decreased expression of DKK1 protein Curcumin inhibits the reaction [bisphenol A results in increased expression of DKK1 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of DKK1 protein]
|
CTD |
PMID:25963729 |
|
NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
|
|
| G
|
Dlg4
|
discs large MAGUK scaffold protein 4
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of DLG4 protein]
|
CTD |
PMID:29723552 |
|
NCBI chr10:55,239,397...55,267,780
Ensembl chr10:55,236,869...55,265,839
|
|
| G
|
Dnajb9
|
DnaJ heat shock protein family (Hsp40) member B9
|
increases expression
|
ISO
|
Curcumin results in increased expression of DNAJB9 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
|
|
| G
|
Dnm1l
|
dynamin 1-like
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Potassium Dichromate results in increased expression of DNM1L protein]
|
CTD |
PMID:32980475 |
|
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
|
|
| G
|
Dnmt1
|
DNA methyltransferase 1
|
increases activity affects expression multiple interactions decreases expression
|
ISO
|
Curcumin results in increased activity of DNMT1 protein Curcumin analog affects the expression of DNMT1 protein Curcumin promotes the reaction [Quercetin results in increased activity of DNMT1 protein]; Quercetin promotes the reaction [Curcumin results in increased activity of DNMT1 protein] Curcumin results in decreased expression of DNMT1 mRNA; Curcumin results in decreased expression of DNMT1 protein Curcumin analog results in decreased expression of DNMT1 protein
|
CTD |
PMID:23593078 PMID:26991801 PMID:27132804 PMID:29228771 |
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
|
|
| G
|
Dnmt3a
|
DNA methyltransferase 3 alpha
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of DNMT3A mRNA Curcumin analog results in decreased expression of DNMT3A protein
|
CTD |
PMID:23593078 PMID:26991801 PMID:29228771 |
|
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
|
|
| G
|
Dnmt3b
|
DNA methyltransferase 3 beta
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of DNMT3B mRNA Curcumin analog results in decreased expression of DNMT3B protein
|
CTD |
PMID:23593078 PMID:26991801 PMID:29228771 |
|
NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313
|
|
| G
|
Dram1
|
DNA-damage regulated autophagy modulator 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of DRAM1 mRNA
|
CTD |
PMID:21594647 |
|
NCBI chr 7:24,630,233...24,665,270
Ensembl chr 7:24,630,238...24,664,354
|
|
| G
|
Drd2
|
dopamine receptor D2
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of DRD2 protein]
|
CTD |
PMID:27966075 |
|
NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339
|
|
| G
|
Dusp1
|
dual specificity phosphatase 1
|
increases expression multiple interactions
|
ISO EXP
|
Curcumin results in increased expression of DUSP1 mRNA Curcumin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of DUSP1 protein]
|
CTD |
PMID:15713895 PMID:20885979 |
|
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
|
|
| G
|
Dusp10
|
dual specificity phosphatase 10
|
increases expression
|
ISO
|
Curcumin results in increased expression of DUSP10 mRNA
|
CTD |
PMID:15713895 PMID:17151092 |
|
NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304
|
|
| G
|
Dusp5
|
dual specificity phosphatase 5
|
increases expression
|
ISO
|
Curcumin results in increased expression of DUSP5 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
|
|
| G
|
Dvl1
|
dishevelled segment polarity protein 1
|
multiple interactions decreases expression increases expression
|
EXP ISO
|
Curcumin inhibits the reaction [bisphenol A results in decreased expression of DVL1 mRNA]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of DVL1 protein] Curcumin results in decreased expression of DVL1 protein Curcumin results in increased expression of DVL1 mRNA; Curcumin results in increased expression of DVL1 protein
|
CTD |
PMID:19573523 PMID:25963729 |
|
NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966
|
|
| G
|
Dynll1
|
dynein light chain LC8-type 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of DYNLL1 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861
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| G
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Dyrk2
|
dual specificity tyrosine phosphorylation regulated kinase 2
|
decreases activity multiple interactions
|
ISO
|
Curcumin results in decreased activity of DYRK2 protein [Curcumin binds to 4-nitrobenzaldehyde] which results in decreased activity of DYRK2 protein
|
CTD |
PMID:33617879 |
|
NCBI chr 7:56,235,276...56,265,741
Ensembl chr 7:56,235,276...56,265,942
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|
| G
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E2f1
|
E2F transcription factor 1
|
decreases expression
|
EXP
|
Curcumin results in decreased expression of E2F1 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
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| G
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E2f5
|
E2F transcription factor 5
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of E2F5 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr 2:88,718,567...88,734,143
Ensembl chr 2:88,718,567...88,734,143
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|
| G
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Ech1
|
enoyl-CoA hydratase 1
|
increases expression
|
EXP
|
Curcumin results in increased expression of ECH1 mRNA
|
CTD |
PMID:18539377 |
|
NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440
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|
| G
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Edaradd
|
EDAR associated via death domain
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of EDARADD mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr17:92,850,791...92,894,808
Ensembl chr17:92,831,613...92,894,361
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| G
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Edem1
|
ER degradation enhancing alpha-mannosidase like protein 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of EDEM1 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060
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|
| G
|
Edil3
|
EGF like repeats and discoidin domains 3
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of EDIL3 mRNA
|
CTD |
PMID:18421014 |
|
NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379
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| G
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Egf
|
epidermal growth factor
|
multiple interactions decreases activity
|
ISO EXP
|
Curcumin inhibits the reaction [EGF protein results in increased expression of AQP3 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [EGF protein results in increased secretion of PTHLH protein] Curcumin results in decreased activity of EGF protein Curcumin inhibits the reaction [EGF protein results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [EGF protein results in decreased expression of PPARG protein]
|
CTD |
PMID:10851300 PMID:15129424 PMID:15486348 PMID:17372590 PMID:18214481 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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|
| G
|
Egfr
|
epidermal growth factor receptor
|
multiple interactions decreases phosphorylation decreases expression
|
ISO EXP
|
Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Curcumin promotes the reaction [Folfox protocol results in decreased expression of EGFR protein]; Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of EGFR protein]; Curcumin results in decreased expression of and results in decreased activity of EGFR protein; Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein; Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein]; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein] Curcumin results in decreased phosphorylation of EGFR protein Curcumin results in decreased expression of EGFR mRNA; Curcumin results in decreased expression of EGFR protein Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]; Curcumin inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] Curcumin analog results in decreased expression of EGFR mRNA; Curcumin results in decreased expression of EGFR mRNA; Curcumin results in decreased expression of EGFR protein
|
CTD |
PMID:10851300 PMID:15129424 PMID:15486348 PMID:17372590 PMID:17918158 PMID:18006644 PMID:18214481 PMID:18332871 PMID:18719366 PMID:24508477 PMID:26409325 PMID:34994998 PMID:37858842 More...
|
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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|
| G
|
Egr1
|
early growth response 1
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
EGR1 protein affects the reaction [Curcumin results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [Curcumin results in increased expression of CDKN1A mRNA]; pyrazolanthrone inhibits the reaction [Curcumin results in increased expression of EGR1 protein]; U 0126 inhibits the reaction [Curcumin results in increased expression of EGR1 protein] Curcumin results in increased expression of EGR1 mRNA; Curcumin results in increased expression of EGR1 protein Curcumin results in decreased expression of EGR1 mRNA
|
CTD |
PMID:17198877 PMID:17999991 PMID:18316600 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
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|
| G
|
Eif1
|
eukaryotic translation initiation factor 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of EIF1 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654 Ensembl chr10:25,895,968...25,896,654
|
|
| G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate results in increased expression of EIF2AK3 protein]
|
CTD |
PMID:34784780 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
multiple interactions decreases expression decreases phosphorylation
|
ISO
|
calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of EIF4EBP1 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of EIF4EBP1 protein] Curcumin results in decreased expression of EIF4EBP1 protein
|
CTD |
PMID:18790744 PMID:23222814 PMID:34634291 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
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|
| G
|
Eif4g1
|
eukaryotic translation initiation factor 4 gamma 1
|
decreases phosphorylation
|
ISO
|
Curcumin results in decreased phosphorylation of EIF4G1 protein
|
CTD |
PMID:18790744 |
|
NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367
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|
| G
|
Elf2
|
E74 like ETS transcription factor 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ELF2 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr 2:137,445,787...137,536,512
Ensembl chr 2:137,445,788...137,470,355
|
|
| G
|
Elk1
|
ETS transcription factor ELK1
|
multiple interactions increases phosphorylation
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of ELK1 mRNA]; pyrazolanthrone inhibits the reaction [Curcumin results in increased phosphorylation of ELK1 protein]; U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of ELK1 protein]
|
CTD |
PMID:18316600 PMID:23452621 |
|
NCBI chr X:3,692,367...3,709,252
Ensembl chr X:3,693,293...3,709,249
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|
| G
|
Emb
|
embigin
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 2:50,803,468...50,858,001
Ensembl chr 2:50,801,973...50,862,920
|
|
| G
|
Eno1
|
enolase 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ENO1 mRNA
|
CTD |
PMID:16880289 |
|
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
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|
| G
|
Entpd5
|
ectonucleoside triphosphate diphosphohydrolase 5
|
increases expression
|
EXP
|
Curcumin results in increased expression of ENTPD5 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495
|
|
| G
|
Ep300
|
E1A binding protein p300
|
multiple interactions decreases activity decreases expression affects localization
|
ISO EXP
|
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 protein]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [EP300 protein binds to KLK3 enhancer]] Curcumin results in decreased activity of EP300 protein Curcumin inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [TP53 protein binds to EP300 protein] Curcumin results in decreased expression of EP300 mRNA; Curcumin results in decreased expression of EP300 protein
|
CTD |
PMID:17927689 PMID:22228707 PMID:22258452 PMID:26612707 |
|
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
|
|
| G
|
Epas1
|
endothelial PAS domain protein 1
|
multiple interactions
|
ISO
|
Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]
|
CTD |
PMID:20554536 |
|
NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
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|
| G
|
Epcam
|
epithelial cell adhesion molecule
|
multiple interactions decreases expression
|
ISO
|
WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of EPCAM mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of EPCAM protein] Curcumin results in decreased expression of EPCAM mRNA; Curcumin results in decreased expression of EPCAM protein
|
CTD |
PMID:33539684 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
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|
| G
|
Epo
|
erythropoietin
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of EPO mRNA
|
CTD |
PMID:16880289 |
|
NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
|
|
| G
|
Epx
|
eosinophil peroxidase
|
multiple interactions
|
ISO
|
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of EPX protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of EPX protein]
|
CTD |
PMID:34998855 |
|
NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180
|
|
| G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
multiple interactions increases response to substance increases degradation decreases expression
|
ISO
|
[ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of AK1 protein; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK1 protein; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK3 protein; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Doxorubicin]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Etoposide]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Paclitaxel]; Curcumin analog promotes the reaction [Cycloheximide results in increased degradation of ERBB2 protein]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein]; Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein ERBB2 protein results in increased susceptibility to Curcumin; ERBB2 protein results in increased susceptibility to Curcumin analog Curcumin analog results in increased degradation of ERBB2 protein Curcumin analog results in decreased expression of ERBB2 mRNA; Curcumin analog results in decreased expression of ERBB2 protein; Curcumin results in decreased expression of ERBB2 mRNA; Curcumin results in decreased expression of ERBB2 protein
|
CTD |
PMID:17041101 PMID:17918158 PMID:18719366 PMID:25866362 PMID:26409325 PMID:34291863 More...
|
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
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|
| G
|
Erbb3
|
erb-b2 receptor tyrosine kinase 3
|
multiple interactions decreases expression
|
ISO
|
Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein; Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein] Curcumin analog results in decreased expression of ERBB3 mRNA; Curcumin results in decreased expression of ERBB3 mRNA
|
CTD |
PMID:15713895 PMID:17918158 PMID:26409325 |
|
NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120
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|
| G
|
Ercc1
|
ERCC excision repair 1, endonuclease non-catalytic subunit
|
multiple interactions decreases expression
|
EXP ISO
|
Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA] [Curcumin results in decreased expression of ERCC1 protein] which results in increased susceptibility to Cisplatin; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein] Curcumin results in decreased expression of ERCC1 mRNA; Curcumin results in decreased expression of ERCC1 protein
|
CTD |
PMID:17596214 PMID:21493726 PMID:22228707 |
|
NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120
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|
| G
|
Ercc4
|
ERCC excision repair 4, endonuclease catalytic subunit
|
multiple interactions decreases expression
|
EXP ISO
|
Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA] Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 protein] Curcumin results in decreased expression of ERCC4 mRNA; Curcumin results in decreased expression of ERCC4 protein
|
CTD |
PMID:22228707 |
|
NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539
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|
| G
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Erlec1
|
endoplasmic reticulum lectin 1
|
increases expression
|
ISO
|
Curcumin results in increased expression of ERLEC1 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr14:108,856,661...108,894,511
Ensembl chr14:108,856,661...108,894,297
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|
| G
|
Ern1
|
endoplasmic reticulum to nucleus signaling 1
|
decreases expression increases expression
|
ISO
|
Curcumin results in decreased expression of ERN1 mRNA Curcumin results in increased expression of ERN1 mRNA
|
CTD |
PMID:17999991 PMID:29723631 |
|
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
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|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of ESR1 protein]; Curcumin inhibits the reaction [Estradiol affects the localization of ESR1 protein]; Curcumin inhibits the reaction [Estradiol results in increased degradation of ESR1 protein]; Curcumin inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein]; Curcumin inhibits the reaction [Fulvestrant results in increased degradation of ESR1 protein] Curcumin results in decreased expression of ESR1 protein
|
CTD |
PMID:15899841 PMID:18347134 PMID:23222814 PMID:24211270 PMID:38229314 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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|
| G
|
Ets2
|
ETS proto-oncogene 2, transcription factor
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ETS2 protein
|
CTD |
PMID:17332326 |
|
NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842
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|
| G
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F2
|
coagulation factor II, thrombin
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [F2 protein results in increased expression of ITGA2B protein]; Curcumin inhibits the reaction [F2 protein results in increased expression of ITGB3 protein]; Curcumin inhibits the reaction [F2 protein results in increased expression of SELE protein]; Curcumin inhibits the reaction [F2 protein results in increased expression of SELP protein]
|
CTD |
PMID:18565277 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
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|
| G
|
F2r
|
coagulation factor II (thrombin) receptor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of F2R mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579
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|
| G
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F3
|
coagulation factor III, tissue factor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Heme results in increased expression of F3 mRNA]
|
CTD |
PMID:18983524 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
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|
| G
|
Fabp3
|
fatty acid binding protein 3
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Gentamicins results in increased expression of FABP3 mRNA]
|
CTD |
PMID:38056816 |
|
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881
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|
| G
|
Fadd
|
Fas associated via death domain
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of FADD mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
|
|
| G
|
Fads1
|
fatty acid desaturase 1
|
affects expression decreases expression
|
ISO EXP
|
Curcumin affects the expression of FADS1 mRNA Curcumin results in decreased expression of FADS1 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615
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|
| G
|
Fads2
|
fatty acid desaturase 2
|
decreases expression affects expression
|
EXP ISO
|
Curcumin results in decreased expression of FADS2 mRNA Curcumin affects the expression of FADS2 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
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|
| G
|
Fam120b
|
family with sequence similarity 120 member B
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FAM120B mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr 1:64,993,104...65,058,160
Ensembl chr 1:65,012,060...65,058,160
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|
| G
|
Fam8a1
|
family with sequence similarity 8, member A1
|
increases expression
|
ISO
|
Curcumin results in increased expression of FAM8A1 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr17:18,232,834...18,241,736
Ensembl chr17:18,232,834...18,241,703
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|
| G
|
Fancd2
|
FA complementation group D2
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [Mitomycin results in increased expression of and affects the ubiquitination of FANCD2 protein] Curcumin results in decreased expression of FANCD2 mRNA
|
CTD |
PMID:24124520 |
|
NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035
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|
| G
|
Fanci
|
FA complementation group I
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [Mitomycin results in increased expression of and affects the ubiquitination of FANCI protein] Curcumin results in decreased expression of FANCI mRNA
|
CTD |
PMID:24124520 |
|
NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:142,736,653...142,792,999
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|
| G
|
Fas
|
Fas cell surface death receptor
|
multiple interactions
|
ISO EXP
|
[arsenic trioxide co-treated with Curcumin] results in increased expression of FAS protein Curcumin inhibits the reaction [fenpropathrin results in increased expression of FAS mRNA]
|
CTD |
PMID:27430728 PMID:38369055 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
| G
|
Faslg
|
Fas ligand
|
multiple interactions decreases expression
|
ISO EXP
|
[arsenic trioxide co-treated with Curcumin] results in increased expression of FASLG protein; Curcumin inhibits the reaction [[vorinostat co-treated with Bortezomib] results in increased expression of FASLG protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA] Curcumin results in decreased expression of FASLG mRNA Curcumin inhibits the reaction [fenpropathrin results in increased expression of FASL mRNA]
|
CTD |
PMID:10925121 PMID:16101141 PMID:17351739 PMID:23452621 PMID:27430728 PMID:38369055 More...
|
|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
|
|
| G
|
Fasn
|
fatty acid synthase
|
affects expression decreases expression
|
ISO EXP
|
Curcumin affects the expression of FASN mRNA; Curcumin affects the expression of FASN protein Curcumin results in decreased expression of FASN mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
|
Fbln2
|
fibulin 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029
|
|
| G
|
Fbxo6
|
F-box protein 6
|
increases expression
|
ISO
|
Curcumin results in increased expression of FBXO6 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr 5:163,859,909...163,865,693
Ensembl chr 5:163,859,916...163,865,574
|
|
| G
|
Fcgr3a
|
Fc gamma receptor 3A
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651
|
|
| G
|
Fdft1
|
farnesyl diphosphate farnesyl transferase 1
|
decreases expression
|
EXP
|
Curcumin results in decreased expression of FDFT1 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
|
|
| G
|
Fdps
|
farnesyl diphosphate synthase
|
affects expression decreases expression increases expression
|
ISO EXP
|
Curcumin affects the expression of FDPS mRNA Curcumin results in decreased expression of FDPS mRNA Curcumin results in increased expression of FDPS mRNA
|
CTD |
PMID:16713233 PMID:27208389 |
|
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
|
|
| G
|
Fgf2
|
fibroblast growth factor 2
|
decreases expression increases expression
|
ISO
|
Curcumin results in decreased expression of FGF2 protein Curcumin results in increased expression of FGF2 protein
|
CTD |
PMID:23555722 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
|
|
| G
|
Fgf5
|
fibroblast growth factor 5
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FGF5 mRNA
|
CTD |
PMID:27237783 |
|
NCBI chr14:11,627,906...11,650,243
Ensembl chr14:11,627,906...11,650,243
|
|
| G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FGFR2 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
|
|
| G
|
Filip1l
|
filamin A interacting protein 1-like
|
increases expression
|
ISO
|
Curcumin results in increased expression of FILIP1L mRNA
|
CTD |
PMID:21594647 |
|
NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402
|
|
| G
|
Fis1
|
fission, mitochondrial 1
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Cisplatin results in increased expression of FIS1 protein]
|
CTD |
PMID:28698153 |
|
NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335
|
|
| G
|
Flt1
|
Fms related receptor tyrosine kinase 1
|
multiple interactions decreases expression
|
EXP ISO
|
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of FLT1 protein] Curcumin results in decreased expression of FLT1 protein
|
CTD |
PMID:18593936 PMID:23845850 |
|
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
|
|
| G
|
Fn1
|
fibronectin 1
|
multiple interactions decreases expression
|
ISO EXP
|
Curcumin inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of FN1 protein] Curcumin inhibits the reaction [sphingosine 1-phosphate results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA] Curcumin results in decreased expression of FN1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA]
|
CTD |
PMID:12388107 PMID:18200517 PMID:18555241 PMID:21998146 PMID:22228707 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Fntb
|
farnesyltransferase, CAAX box, subunit beta
|
increases expression
|
ISO
|
Curcumin results in increased expression of FNTB mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr 6:101,269,657...101,352,716
Ensembl chr 6:101,269,671...101,352,716
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of FOS mRNA] Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of FOS protein] Curcumin results in decreased expression of FOS mRNA Curcumin results in increased expression of FOS mRNA [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of FOS protein]
|
CTD |
PMID:15713895 PMID:17827730 PMID:17999991 PMID:23452621 PMID:26191140 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
multiple interactions increases ubiquitination
|
ISO
|
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein] Curcumin results in increased ubiquitination of FOSL1 protein
|
CTD |
PMID:17148446 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
|
|
| G
|
Fosl2
|
FOS like 2, AP-1 transcription factor subunit
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of FOSL2 mRNA Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein]
|
CTD |
PMID:17148446 PMID:17999991 |
|
NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406
|
|
| G
|
Foxa1
|
forkhead box A1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to TMPRSS2 enhancer]]
|
CTD |
PMID:22258452 |
|
NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
|
|
| G
|
Foxa2
|
forkhead box A2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FOXA2 mRNA
|
CTD |
PMID:27237783 |
|
NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757
|
|
| G
|
Foxf2
|
forkhead box F2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FOXF2 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr17:33,044,446...33,051,259
Ensembl chr17:32,846,603...33,051,259
|
|
| G
|
Foxo1
|
forkhead box O1
|
increases expression decreases phosphorylation
|
ISO
|
Curcumin results in increased expression of FOXO1 mRNA Curcumin results in decreased phosphorylation of FOXO1 protein
|
CTD |
PMID:18403477 PMID:18790744 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
|
|
| G
|
Fpr3
|
formyl peptide receptor 3
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 1:67,557,464...67,566,509
Ensembl chr 1:67,518,199...67,566,519
|
|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of FSHB protein]
|
CTD |
PMID:31199764 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
|
|
| G
|
Fstl1
|
follistatin-like 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126
|
|
| G
|
Fth1
|
ferritin heavy chain 1
|
multiple interactions
|
EXP ISO
|
Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of FTH1 protein] Curcumin inhibits the reaction [Firemaster BP-6 results in decreased expression of FTH1 protein]
|
CTD |
PMID:34787501 PMID:39934342 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
|
|
| G
|
Ftl1
|
ferritin light chain 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FTL1 mRNA
|
CTD |
PMID:24634837 |
|
NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915 Ensembl chr 2:45,399,355...45,399,915 Ensembl chr 1:45,399,355...45,399,915
|
|
| G
|
Fus
|
Fus RNA binding protein
|
increases expression decreases expression
|
ISO
|
Curcumin results in increased expression of FUS mRNA Curcumin results in decreased expression of FUS mRNA
|
CTD |
PMID:17198877 PMID:17999991 |
|
NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884
|
|
| G
|
Fzd1
|
frizzled class receptor 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of FZD1 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176
|
|
| G
|
G6pc1
|
glucose-6-phosphatase catalytic subunit 1
|
affects expression
|
ISO
|
Curcumin affects the expression of G6PC1 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
|
|
| G
|
G6pd
|
glucose-6-phosphate dehydrogenase
|
increases expression multiple interactions
|
EXP ISO
|
Curcumin results in increased expression of G6PD mRNA; Curcumin results in increased expression of G6PDX mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of G6PD protein]
|
CTD |
PMID:18299980 PMID:36924976 |
|
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
|
|
| G
|
Gabra1
|
gamma-aminobutyric acid type A receptor subunit alpha 1
|
decreases expression
|
EXP
|
Curcumin results in decreased expression of GABRA1 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442
|
|
| G
|
Gad1
|
glutamate decarboxylase 1
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]
|
CTD |
PMID:23267840 |
|
NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
increases expression
|
EXP ISO
|
Curcumin results in increased expression of GADD45A mRNA
|
CTD |
PMID:16101141 PMID:18299980 PMID:18719366 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Gas6
|
growth arrest specific 6
|
increases expression
|
ISO
|
Curcumin results in increased expression of GAS6 mRNA
|
CTD |
PMID:21594647 |
|
NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
|
|
| G
|
Gata2
|
GATA binding protein 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to TMPRSS2 enhancer]]; Curcumin inhibits the reaction [GATA2 protein results in increased expression of KLK3 mRNA]
|
CTD |
PMID:22258452 |
|
NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055
|
|
| G
|
Gata4
|
GATA binding protein 4
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of GATA4 mRNA; Curcumin results in decreased expression of GATA4 protein
|
CTD |
PMID:27237783 |
|
NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
increases activity multiple interactions increases expression
|
ISO EXP
|
Curcumin results in increased activity of GCLC protein Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA] Curcumin results in increased expression of GCLC mRNA; Curcumin results in increased expression of GCLC protein Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC protein]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein]; Curcumin results in increased activity of [GCLC protein binds to GCLM protein] Curcumin analog results in increased expression of GCLC mRNA; Curcumin results in increased expression of GCLC mRNA Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of GCLC mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of GCLC protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]
|
CTD |
PMID:10514034 PMID:17602960 PMID:18299980 PMID:18332871 PMID:19168576 PMID:19183254 PMID:23710286 PMID:23954767 PMID:27837179 PMID:29571711 PMID:31521693 PMID:34272803 PMID:35063475 PMID:35817260 PMID:36305173 PMID:38141737 More...
|
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
multiple interactions increases expression
|
EXP ISO
|
Curcumin results in increased activity of [GCLC protein binds to GCLM protein] Curcumin promotes the reaction [sodium arsenite results in increased expression of GCLM mRNA] Curcumin analog results in increased expression of GCLM mRNA; Curcumin results in increased expression of GCLM mRNA; Curcumin results in increased expression of GCLM protein NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLM mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLM mRNA]
|
CTD |
PMID:17198877 PMID:17535857 PMID:17602960 PMID:17999991 PMID:18332871 PMID:19168576 PMID:19183254 PMID:19188863 PMID:23386263 PMID:23710286 PMID:23954767 PMID:29571711 PMID:34272803 More...
|
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
|
|
| G
|
Gda
|
guanine deaminase
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348
|
|
| G
|
Gfap
|
glial fibrillary acidic protein
|
multiple interactions decreases expression
|
EXP ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of GFAP mRNA] Curcumin results in decreased expression of GFAP mRNA
|
CTD |
PMID:19555370 PMID:25963729 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
|
|
| G
|
Ggt1
|
gamma-glutamyltransferase 1
|
increases expression multiple interactions
|
EXP
|
Curcumin results in increased expression of GGT1 mRNA Curcumin inhibits the reaction [Thioacetamide results in increased expression of GGT1 protein]
|
CTD |
PMID:18299980 PMID:24704557 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
|
|
| G
|
Ggta1
|
glycoprotein alpha-galactosyltransferase 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 3:39,130,466...39,208,652
Ensembl chr 3:39,130,467...39,206,870
|
|
| G
|
Gja1
|
gap junction protein, alpha 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
| G
|
Gli1
|
GLI family zinc finger 1
|
decreases expression multiple interactions
|
ISO EXP
|
Curcumin results in decreased expression of GLI1 mRNA; Curcumin results in decreased expression of GLI1 protein [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]
|
CTD |
PMID:20395211 PMID:31612257 |
|
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
|
|
| G
|
Gli2
|
GLI family zinc finger 2
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Cisplatin results in increased expression of GLI2 protein]; Curcumin promotes the reaction [Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI2 protein]]
|
CTD |
PMID:31612257 |
|
NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418
|
|
| G
|
Glo1
|
glyoxalase 1
|
decreases activity
|
ISO
|
Curcumin results in decreased activity of GLO1 protein
|
CTD |
PMID:18946510 |
|
NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,665,061...8,683,191
|
|
| G
|
Got1
|
glutamic-oxaloacetic transaminase 1
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [aristolochic acid I results in increased activity of GOT1 protein]; Curcumin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; Curcumin inhibits the reaction [Iron results in increased activity of GOT1 protein]
|
CTD |
PMID:16956363 PMID:36037877 |
|
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
|
|
| G
|
Got1l1
|
glutamic-oxaloacetic transaminase 1-like 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr16:71,563,562...71,576,446
Ensembl chr16:71,563,534...71,570,468
|
|
| G
|
Gpam
|
glycerol-3-phosphate acyltransferase, mitochondrial
|
affects expression decreases expression multiple interactions
|
ISO EXP
|
Curcumin affects the expression of GPAM mRNA Curcumin results in decreased expression of GPAM mRNA Curcumin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA]
|
CTD |
PMID:19297423 PMID:27208389 |
|
NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911
|
|
| G
|
Gper1
|
G protein-coupled estrogen receptor 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of GPER1 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
|
|
| G
|
Gphn
|
gephyrin
|
affects expression
|
EXP
|
Curcumin affects the expression of GPHN mRNA
|
CTD |
PMID:18539377 |
|
NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:102,687,423...103,216,674
|
|
| G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
EXP ISO
|
[Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein]; Curcumin inhibits the reaction [Acetaminophen affects the activity of GPT protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased activity of GPT protein]; Curcumin inhibits the reaction [Cadmium Chloride results in increased activity of GPT protein]; Curcumin inhibits the reaction [Fenitrothion results in increased expression of GPT protein]; Curcumin inhibits the reaction [ferric sulfate results in increased activity of GPT protein]; Curcumin inhibits the reaction [Iron results in increased activity of GPT protein]; Curcumin inhibits the reaction [Tartrazine results in increased activity of GPT protein]; Curcumin inhibits the reaction [Thioacetamide results in increased activity of GPT protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of GPT protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased activity of GPT protein]] Curcumin inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein]; Curcumin inhibits the reaction [bisphenol A results in increased activity of GPT protein]; Curcumin inhibits the reaction [Chloranil results in increased activity of GPT protein]; Curcumin inhibits the reaction [Firemaster BP-6 results in increased expression of GPT protein]; Curcumin metabolite inhibits the reaction [Acetaminophen results in increased expression of GPT protein]
|
CTD |
PMID:16956363 PMID:20804811 PMID:24704557 PMID:25123790 PMID:27288928 PMID:28239801 PMID:29421648 PMID:30423402 PMID:32718261 PMID:34802538 PMID:35063475 PMID:36037877 PMID:37701206 PMID:39934342 More...
|
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
| G
|
Gpx1
|
glutathione peroxidase 1
|
decreases expression multiple interactions
|
EXP ISO
|
Curcumin results in decreased expression of GPX1 mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of GPX1 protein] Curcumin inhibits the reaction [Atrazine results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA] [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in increased expression of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of GPX1 mRNA]
|
CTD |
PMID:18299980 PMID:19914224 PMID:23267840 PMID:30934151 PMID:36924976 PMID:38301994 More...
|
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
| G
|
Gpx4
|
glutathione peroxidase 4
|
multiple interactions
|
EXP ISO
|
Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of GPX4 protein] Curcumin inhibits the reaction [Firemaster BP-6 results in decreased expression of GPX4 protein]
|
CTD |
PMID:34787501 PMID:39934342 |
|
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
|
|
| G
|
Grb10
|
growth factor receptor bound protein 10
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
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|
| G
|
Grb2
|
growth factor receptor bound protein 2
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of GRB2 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138
|
|
| G
|
Grem1
|
gremlin 1, DAN family BMP antagonist
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089
|
|
| G
|
Gria4
|
glutamate ionotropic receptor AMPA type subunit 4
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]
|
CTD |
PMID:23267840 |
|
NCBI chr 8:9,845,421...10,320,021
Ensembl chr 8:9,847,052...10,319,881
|
|
| G
|
Grin1
|
glutamate ionotropic receptor NMDA type subunit 1
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]
|
CTD |
PMID:23267840 PMID:29723552 |
|
NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754
|
|
| G
|
Grin2a
|
glutamate ionotropic receptor NMDA type subunit 2A
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [aluminum acetate results in decreased expression of GRIN2A protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN2A mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN2A protein]
|
CTD |
PMID:25496357 PMID:29723552 |
|
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378
|
|
| G
|
Grin2b
|
glutamate ionotropic receptor NMDA type subunit 2B
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [aluminum acetate results in decreased expression of GRIN2B protein]
|
CTD |
PMID:25496357 |
|
NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570
|
|
| G
|
Grm2
|
glutamate metabotropic receptor 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of GRM2 protein
|
CTD |
PMID:25406541 |
|
NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:116,158,810...116,171,857
|
|
| G
|
Gsdmd
|
gasdermin D
|
multiple interactions
|
ISO EXP
|
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of GSDMD protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of GSDMD mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of GSDMD protein]; Curcumin inhibits the reaction [Atrazine results in increased expression of GSDMD mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of GSDMD protein] Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in decreased expression of GSDMD mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in decreased expression of GSDMD mRNA]
|
CTD |
PMID:34998855 PMID:35063475 PMID:38301994 PMID:38369055 |
|
NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
decreases phosphorylation decreases expression multiple interactions increases phosphorylation increases expression
|
ISO EXP
|
Curcumin results in decreased phosphorylation of GSK3B protein Curcumin results in decreased expression of GSK3B mRNA Curcumin inhibits the reaction [IL1B protein results in decreased expression of GSK3B mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; Curcumin results in increased expression of and results in increased phosphorylation of GSK3B protein Curcumin results in increased phosphorylation of GSK3B protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein]; Curcumin inhibits the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of GSK3B mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of and affects the localization of GSK3B protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] Curcumin results in increased expression of GSK3B protein
|
CTD |
PMID:18006147 PMID:18790744 PMID:19573523 PMID:25541178 PMID:25963729 PMID:27645308 PMID:27966075 PMID:29723552 PMID:34577062 More...
|
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Gsn
|
gelsolin
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
increases expression multiple interactions
|
ISO EXP
|
Curcumin results in increased expression of GSR mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of GSR protein] [Curcumin co-treated with resveratrol] inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GSR] [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]; Curcumin analog inhibits the reaction [Monocrotaline results in increased activity of GSR protein]; Curcumin analog inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Curcumin inhibits the reaction [Fenitrothion results in decreased activity of GSR protein]; Curcumin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of GSR protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]
|
CTD |
PMID:19168576 PMID:19914224 PMID:20593964 PMID:21976817 PMID:24347089 PMID:25632966 PMID:31407471 PMID:34802538 PMID:36924976 More...
|
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Gss
|
glutathione synthetase
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of GSS mRNA Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of GSS mRNA]
|
CTD |
PMID:19183254 PMID:35063475 |
|
NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306
|
|
| G
|
Gsta2
|
glutathione S-transferase alpha 2
|
increases expression
|
ISO
|
Curcumin results in increased expression of GSTA2 mRNA
|
CTD |
PMID:18200517 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
|
|
| G
|
Gsta4
|
glutathione S-transferase alpha 4
|
increases activity
|
ISO
|
Curcumin results in increased activity of GSTA4 protein
|
CTD |
PMID:10514034 |
|
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488
|
|
| G
|
Gsta5
|
glutathione S-transferase alpha 5
|
increases expression
|
EXP
|
Curcumin results in increased expression of GSTA5 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
|
|
| G
|
Gstk1
|
glutathione S-transferase kappa 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GSTK1 mRNA]
|
CTD |
PMID:31521693 |
|
NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927
|
|
| G
|
Gsto1
|
glutathione S-transferase omega 1
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of GSTO1 mRNA Curcumin promotes the reaction [sodium arsenite results in increased expression of GSTO1 mRNA]
|
CTD |
PMID:34272803 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions affects expression increases expression decreases expression
|
ISO EXP
|
[sulfinosine co-treated with Curcumin] results in decreased expression of GSTP1 mRNA; Curcumin binds to and results in decreased activity of GSTP1 protein; Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Curcumin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Curcumin promotes the reaction [NFE2L2 protein binds to GSTP1 promoter]; Curcumin promotes the reaction [NFE2L2 protein results in increased expression of GSTP1 mRNA] Curcumin affects the expression of GSTP1 protein Curcumin results in increased expression of GSTP1 mRNA Curcumin results in decreased expression of GSTP1 mRNA; Curcumin results in decreased expression of GSTP1 protein Curcumin results in increased expression of GSTP1 mRNA; Curcumin results in increased expression of GSTP1 protein
|
CTD |
PMID:9463521 PMID:14555224 PMID:14742295 PMID:15999103 PMID:16101141 PMID:17449203 PMID:18299980 PMID:18414057 PMID:22830632 More...
|
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Gusb
|
glucuronidase, beta
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]
|
CTD |
PMID:8534267 |
|
NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024
|
|
| G
|
Gzma
|
granzyme A
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [fenpropathrin results in increased expression of GZMA mRNA]
|
CTD |
PMID:38369055 |
|
NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
|
|
| G
|
H19
|
H19 imprinted maternally expressed transcript
|
decreases expression multiple interactions
|
ISO EXP
|
Curcumin results in decreased expression of H19 mRNA curcumin inhibits the reaction [platelet- derived growth factor increases expression of H19 RNA in aortic vascular smooth muscle cells] curcumin inhibits the reaction [carotid balloon injury increases expression of H19 RNA in carotid artery segment]
|
CTD RGD |
PMID:18348204 PMID:34487706 PMID:34487706 |
RGD:156430326, RGD:156430326 |
NCBI chr 1:207,160,175...207,162,851
|
|
| G
|
H1f10
|
H1.10 linker histone
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of H1-10 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 4:121,997,834...121,998,897
Ensembl chr 4:121,997,831...121,998,966
|
|
| G
|
H2ax
|
H2A.X variant histone
|
multiple interactions increases phosphorylation
|
ISO
|
[Curcumin co-treated with Metribolone] results in increased phosphorylation of H2AX protein; [Isoflavones co-treated with Curcumin] results in increased phosphorylation of H2AX protein Curcumin results in increased phosphorylation of H2AX protein
|
CTD |
PMID:19401701 PMID:21134073 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
H2bc14
|
H2B clustered histone 14
|
increases expression
|
ISO
|
Curcumin results in increased expression of H2BC5 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr17:47,488,627...47,489,008
|
|
| G
|
H2bc27
|
H2B clustered histone 27
|
increases expression
|
ISO
|
Curcumin results in increased expression of H2BC26 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr10:44,232,318...44,233,065
Ensembl chr10:44,232,318...44,233,065
|
|
| G
|
H3f4
|
H3.4 histone, cluster member
|
increases acetylation increases phosphorylation
|
EXP
|
Curcumin results in increased acetylation of H3F4 protein Curcumin results in increased phosphorylation of H3F4 protein
|
CTD |
PMID:18204486 |
|
NCBI chr10:44,240,282...44,240,842
|
|
| G
|
Hamp
|
hepcidin antimicrobial peptide
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of HAMP mRNA
|
CTD |
PMID:24634837 |
|
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297
|
|
| G
|
Hand1
|
heart and neural crest derivatives expressed 1
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [Alcohols results in increased expression of HAND1 mRNA] Curcumin results in decreased expression of HAND1 mRNA
|
CTD |
PMID:24857828 |
|
NCBI chr10:42,507,117...42,509,684
Ensembl chr10:42,507,122...42,509,684
|
|
| G
|
Hand2
|
heart and neural crest derivatives expressed 2
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [Alcohols results in increased expression of HAND2 mRNA] Curcumin results in decreased expression of HAND2 mRNA
|
CTD |
PMID:24857828 |
|
NCBI chr16:37,928,145...37,931,488
Ensembl chr16:37,928,145...37,931,488
|
|
| G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions
|
EXP
|
Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein]; Curcumin inhibits the reaction [Cadmium Chloride results in increased export of HAVCR1 protein]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein]; Curcumin inhibits the reaction [Gentamicins results in increased expression of HAVCR1 mRNA]; Curcumin inhibits the reaction [maleic acid results in increased expression of HAVCR1 protein]
|
CTD |
PMID:25119790 PMID:29421648 PMID:30431687 PMID:38056816 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
|
|
| G
|
Hbs1l
|
HBS1-like translational GTPase
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of HBS1L mRNA
|
CTD |
PMID:18421014 |
|
NCBI chr 1:17,912,139...17,989,651
Ensembl chr 1:17,912,070...17,989,646
|
|
| G
|
Hck
|
HCK proto-oncogene, Src family tyrosine kinase
|
decreases activity multiple interactions
|
ISO
|
Curcumin analog results in decreased activity of HCK protein [Curcumin binds to 3,4,5-trimethoxybenzaldehyde] which results in decreased activity of HCK protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [HCK protein binds to Adenosine Triphosphate]; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which binds to and results in decreased phosphorylation of and results in decreased activity of HCK protein
|
CTD |
PMID:33617879 |
|
NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935
|
|
| G
|
Hdac1
|
histone deacetylase 1
|
decreases expression multiple interactions affects localization
|
ISO
|
Curcumin analog results in decreased expression of HDAC1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein] Curcumin analog results in decreased expression of HDAC1 mRNA; Curcumin results in decreased expression of HDAC1 mRNA; Curcumin results in decreased expression of HDAC1 protein
|
CTD |
PMID:17927689 PMID:18161303 PMID:23593078 PMID:26409325 PMID:29228771 |
|
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
|
|
| G
|
Hdac11
|
histone deacetylase 11
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of HDAC11 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 4:125,203,044...125,224,584
Ensembl chr 4:125,202,299...125,224,582
|
|
| G
|
Hdac2
|
histone deacetylase 2
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased activity of HDAC2 protein]; Curcumin inhibits the reaction [Smoke results in decreased activity of HDAC2 protein]; Curcumin inhibits the reaction [Smoke results in increased degradation of and results in decreased expression of HDAC2 protein] Curcumin analog results in decreased expression of HDAC2 mRNA
|
CTD |
PMID:18421014 PMID:26409325 |
|
NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311
|
|
| G
|
Hdac3
|
histone deacetylase 3
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of HDAC3 protein
|
CTD |
PMID:17927689 |
|
NCBI chr18:30,021,847...30,041,061
Ensembl chr18:30,021,941...30,041,025
|
|
| G
|
Hdac4
|
histone deacetylase 4
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of HDAC4 mRNA Curcumin analog results in decreased expression of HDAC4 protein
|
CTD |
PMID:26409325 PMID:26991801 PMID:29228771 |
|
NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:99,955,116...100,197,637
|
|
| G
|
Hdac6
|
histone deacetylase 6
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of HDAC6 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr X:17,222,538...17,244,373
Ensembl chr X:17,222,856...17,244,370
|
|
| G
|
Hdac7
|
histone deacetylase 7
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of HDAC7 protein
|
CTD |
PMID:29228771 |
|
NCBI chr 7:130,803,013...130,841,181
Ensembl chr 7:130,803,013...130,841,017
|
|
| G
|
Hdac8
|
histone deacetylase 8
|
decreases expression
|
ISO
|
Curcumin analog results in decreased expression of HDAC8 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr X:71,425,240...71,632,865
Ensembl chr X:71,394,928...71,632,865
|
|
| G
|
Hebp2
|
heme binding protein 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 1:15,014,729...15,021,523
Ensembl chr 1:15,014,729...15,021,523
|
|
| G
|
Hes1
|
hes family bHLH transcription factor 1
|
multiple interactions
|
ISO
|
[1,2-Dimethylhydrazine co-treated with Curcumin] results in increased expression of HES1 mRNA
|
CTD |
PMID:22982865 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
|
|
| G
|
Hgf
|
hepatocyte growth factor
|
increases expression decreases expression
|
ISO
|
Curcumin results in increased expression of HGF protein Curcumin results in decreased expression of HGF protein
|
CTD |
PMID:23555722 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
multiple interactions decreases expression decreases activity
|
ISO EXP
|
[Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; [Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; [Curcumin analog co-treated with Vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]; Curcumin analog inhibits the reaction [Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; Curcumin analog inhibits the reaction [Ionomycin results in increased activity of HIF1A protein]; Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of HIF1A protein]; Curcumin results in decreased expression of and results in decreased activity of HIF1A protein; VHL protein promotes the reaction [Curcumin results in decreased expression of HIF1A protein] Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A protein] Curcumin results in decreased expression of HIF1A mRNA Curcumin analog results in decreased expression of HIF1A mRNA; Curcumin results in decreased expression of HIF1A mRNA Curcumin results in decreased activity of HIF1A protein
|
CTD |
PMID:16880289 PMID:18682687 PMID:20554536 PMID:21397623 PMID:23845850 PMID:26409325 More...
|
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hist1h2bq
|
histone cluster 1 H2B family member Q
|
increases expression
|
EXP
|
Curcumin results in increased expression of HIST1H2BQ mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr17:41,859,955...41,869,889
Ensembl chr17:41,857,231...41,870,107 Ensembl chr17:41,857,231...41,870,107
|
|
| G
|
Hk1
|
hexokinase 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of HK1 protein]
|
CTD |
PMID:36924976 |
|
NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814
|
|
| G
|
Hk2
|
hexokinase 2
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of HK2 protein 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [Curcumin results in decreased expression of HK2 protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of HK2 protein]; Curcumin promotes the reaction [Sirolimus results in decreased expression of HK2 protein]
|
CTD |
PMID:36640941 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
|
|
| G
|
Hmgb1
|
high mobility group box 1
|
multiple interactions
|
EXP
|
bisphenol A diglycidyl ether inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]]; Curcumin inhibits the reaction [Carbon Tetrachloride affects the localization of and affects the secretion of HMGB1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMGB1 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMGB1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]
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CTD |
PMID:22683883 PMID:29480285 |
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NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
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| G
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Hmgcr
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
increases expression multiple interactions decreases expression affects expression
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ISO EXP
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Curcumin results in increased expression of HMGCR mRNA Curcumin inhibits the reaction [bisphenol A results in increased expression of HMGCR protein] Curcumin results in decreased expression of HMGCR mRNA Curcumin affects the expression of HMGCR mRNA; Curcumin affects the expression of HMGCR protein
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CTD |
PMID:16713233 PMID:27208389 PMID:37701206 |
|
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
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| G
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Hmgcs1
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3-hydroxy-3-methylglutaryl-CoA synthase 1
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decreases expression
|
EXP
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Curcumin results in decreased expression of HMGCS1 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
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| G
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Hmox1
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heme oxygenase 1
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multiple interactions decreases expression increases expression decreases response to substance increases activity
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ISO EXP
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2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [Furazolidone results in increased expression of HMOX1 protein]; Curcumin promotes the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [quinocetone results in increased activity of HMOX1 protein]; Curcumin promotes the reaction [quinocetone results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Curcumin results in increased expression of and results in increased activity of HMOX1 protein; Cycloheximide inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Egtazic Acid inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Go 6976 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Hemin promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA]; MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]]; PRKCA protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; PRKCD protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; Ro 31-8220 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [Curcumin results in increased activity of HMOX1 protein] Curcumin results in decreased expression of HMOX1 mRNA Curcumin analog results in increased expression of HMOX1 mRNA; Curcumin analog results in increased expression of HMOX1 protein; Curcumin results in increased expression of HMOX1 mRNA; Curcumin results in increased expression of HMOX1 protein [chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]] which results in increased expression of HMOX1 protein; [Curcumin co-treated with Chloranil] results in increased expression of HMOX1 protein; [Curcumin co-treated with piperine] results in increased expression of HMOX1 mRNA; [Curcumin co-treated with piperine] results in increased expression of HMOX1 protein; [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; [Lipopolysaccharides co-treated with Curcumin] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [[Curcumin co-treated with piperine] results in increased expression of HMOX1 protein]; AKT1 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of HMOX1 mRNA]; Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]; Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Curcumin results in increased expression of and results in increased activity of HMOX1 protein; KEAP1 protein inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; linderalactone promotes the reaction [[Lipopolysaccharides co-treated with Curcumin] results in increased expression of HMOX1 protein]; NFE2L2 gene mutant form affects the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] Curcumin analog results in increased expression of HMOX1 mRNA; Curcumin analog results in increased expression of HMOX1 protein; Curcumin results in increased expression of HMOX1; Curcumin results in increased expression of HMOX1 mRNA; Curcumin results in increased expression of HMOX1 protein HMOX1 protein results in decreased susceptibility to Curcumin [Curcumin co-treated with Fructose] results in increased expression of HMOX1 protein; [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in decreased expression of HMOX1 protein]; bisphenol A diglycidyl ether inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Atrazine results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [decamethrin results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Ethanol results in decreased activity of HMOX1 protein]; Curcumin inhibits the reaction [Gentamicins results in increased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Thioacetamide results in decreased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein]; Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]; Curcumin promotes the reaction [Sildenafil Citrate results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [Sildenafil Citrate results in increased expression of HMOX1 protein]; Curcumin results in increased expression of and results in increased activity of HMOX1 protein; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in decreased expression of HMOX1 mRNA]]; Quartz promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA]; tin protoporphyrin IX inhibits the reaction [Curcumin results in increased activity of HMOX1 protein]
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CTD |
PMID:10925121 PMID:14742295 PMID:17464175 PMID:17535857 PMID:17627722 PMID:17973899 PMID:17999991 PMID:18001810 PMID:18006204 PMID:18299980 PMID:18357586 PMID:18719366 PMID:18784349 PMID:19168576 PMID:19177192 PMID:19188863 PMID:20080166 PMID:20938987 PMID:22771723 PMID:23266269 PMID:23386263 PMID:23452621 PMID:23710286 PMID:23871787 PMID:23942037 PMID:23954767 PMID:24211270 PMID:24863870 PMID:24952339 PMID:25123790 PMID:25169090 PMID:25268984 PMID:25387343 PMID:25541178 PMID:26260164 PMID:26361869 PMID:26991801 PMID:27375190 PMID:27837179 PMID:27966075 PMID:27996348 PMID:29228771 PMID:29480285 PMID:29571711 PMID:30946834 PMID:31187328 PMID:31330227 PMID:31454128 PMID:31521693 PMID:32718261 PMID:33350580 PMID:34272803 PMID:34758851 PMID:35063475 PMID:35817260 PMID:36037877 PMID:36305173 PMID:37741124 PMID:38056816 PMID:38141737 More...
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|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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| G
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Hnrnpa1
|
heterogeneous nuclear ribonucleoprotein A1
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decreases expression
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ISO
|
Curcumin results in decreased expression of HNRNPA1 mRNA
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CTD |
PMID:17999991 |
|
NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085
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|
| G
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Hnrnpd
|
heterogeneous nuclear ribonucleoprotein D
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decreases expression
|
ISO
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Curcumin results in decreased expression of HNRNPD mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,919,739...9,938,066
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| G
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Hopx
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HOP homeobox
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increases expression
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EXP
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Curcumin results in increased expression of HOPX mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr14:31,410,235...31,437,189
Ensembl chr14:31,410,221...31,437,188
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|
| G
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Hoxb5
|
homeo box B5
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increases expression
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ISO
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Curcumin results in increased expression of HOXB5 mRNA
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CTD |
PMID:18421014 |
|
NCBI chr10:81,765,911...81,768,119
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|
| G
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Hprt1
|
hypoxanthine phosphoribosyltransferase 1
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increases expression
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ISO
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Curcumin results in increased expression of HPRT1 mRNA
|
CTD |
PMID:16101141 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
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| G
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Hsf1
|
heat shock transcription factor 1
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multiple interactions
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EXP ISO
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[arsenite co-treated with Curcumin] results in increased phosphorylation of HSF1 protein Curcumin promotes the reaction [HSF1 protein binds to HSF1 protein]
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CTD |
PMID:9764755 PMID:11322385 |
|
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
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|
| G
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Hsp90aa1
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heat shock protein 90 alpha family class A member 1
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decreases expression
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ISO
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Curcumin analog results in decreased expression of HSP90AA1 mRNA
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CTD |
PMID:26409325 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
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| G
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Hsp90ab1
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heat shock protein 90 alpha family class B member 1
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multiple interactions
|
EXP
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Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA]
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CTD |
PMID:26361869 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
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| G
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Hsp90b1
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heat shock protein 90 beta family member 1
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decreases expression
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ISO
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Curcumin analog results in decreased expression of HSP90B1 mRNA
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CTD |
PMID:26409325 |
|
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
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| G
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Hspa1a
|
heat shock protein family A (Hsp70) member 1A
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increases expression multiple interactions decreases expression
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ISO EXP
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Curcumin results in increased expression of HSPA1A mRNA; Curcumin results in increased expression of HSPA1A protein Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSPA1A mRNA] Curcumin results in decreased expression of HSPA1A protein
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CTD |
PMID:23555722 PMID:26361869 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
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| G
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Hspa4
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heat shock protein family A (Hsp70) member 4
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increases expression
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ISO
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Curcumin results in increased expression of HSPA4 mRNA; Curcumin results in increased expression of HSPA4 protein
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CTD |
PMID:11322385 |
|
NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835
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| G
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Hspa5
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heat shock protein family A (Hsp70) member 5
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increases expression multiple interactions decreases expression
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ISO
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Curcumin results in increased expression of HSPA5 mRNA Curcumin inhibits the reaction [bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate results in increased expression of HSPA5 protein] Curcumin results in decreased expression of HSPA5 protein 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of HSPA5 protein]; Curcumin inhibits the reaction [Furazolidone results in increased expression of HSPA5 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein]
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CTD |
PMID:18200517 PMID:27996348 PMID:29723631 PMID:34784780 PMID:36640941 |
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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| G
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Hspb1
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heat shock protein family B (small) member 1
|
multiple interactions
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EXP
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Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein]; Curcumin promotes the reaction [Isoproterenol results in increased expression of HSPB1 protein]
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CTD |
PMID:18204486 PMID:20125031 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
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| G
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Hspb7
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heat shock protein family B (small) member 7
|
multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA]
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CTD |
PMID:18200517 |
|
NCBI chr 5:159,010,759...159,014,245
Ensembl chr 5:159,010,629...159,014,243
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| G
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Hspd1
|
heat shock protein family D (Hsp60) member 1
|
multiple interactions
|
EXP ISO
|
Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSPD1 mRNA] [arsenic trioxide co-treated with Curcumin] results in increased expression of HSPD1 protein
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CTD |
PMID:26361869 PMID:27430728 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
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| G
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Htr1a
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5-hydroxytryptamine receptor 1A
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affects expression
|
EXP
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Curcumin affects the expression of HTR1A mRNA
|
CTD |
PMID:17617388 |
|
NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760
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| G
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Icam1
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intercellular adhesion molecule 1
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multiple interactions decreases expression affects expression
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ISO EXP
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[Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [Particulate Matter results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] Curcumin analog inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [Methotrexate results in increased expression of ICAM1 mRNA]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CDH2 protein]]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] [chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]] which results in increased expression of HMOX1 protein; [Curcumin co-treated with Gemcitabine] results in decreased expression of ICAM1 protein; [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] Curcumin results in decreased expression of ICAM1 protein Curcumin affects the expression of ICAM1 mRNA
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CTD |
PMID:16219905 PMID:16243823 PMID:17440100 PMID:17666914 PMID:17973899 PMID:18200517 PMID:18752423 PMID:20885979 PMID:28700904 PMID:29244817 PMID:35549587 More...
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NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
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| G
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Id1
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inhibitor of DNA binding 1
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decreases expression
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ISO
|
Curcumin results in decreased expression of ID1 mRNA
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CTD |
PMID:21594647 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
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| G
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Id2
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inhibitor of DNA binding 2
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decreases expression
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ISO
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Curcumin results in decreased expression of ID2 mRNA
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CTD |
PMID:21594647 |
|
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
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|
| G
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Id3
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inhibitor of DNA binding 3
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decreases expression
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ISO
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Curcumin results in decreased expression of ID3 mRNA
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CTD |
PMID:21594647 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
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|
| G
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Ido1
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indoleamine 2,3-dioxygenase 1
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decreases expression
|
ISO
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Curcumin results in decreased expression of IDO1 mRNA
|
CTD |
PMID:18348204 |
|
NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328
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|
| G
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Ifna1
|
interferon, alpha 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [IFNA1 protein results in increased expression of IFNAR2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IFNA1 mRNA]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IFNAR1 protein]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein]
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CTD |
PMID:17979888 PMID:23452621 |
|
NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809
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|
| G
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Ifnar1
|
interferon alpha and beta receptor subunit 1
|
multiple interactions
|
ISO
|
Curcumin promotes the reaction [IFNA1 protein results in increased expression of IFNAR1 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR1 protein]
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CTD |
PMID:17979888 |
|
NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205
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| G
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Ifnar2
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interferon alpha and beta receptor subunit 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [IFNA1 protein results in increased expression of IFNAR2 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR2 protein]
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CTD |
PMID:17979888 |
|
NCBI chr11:44,099,574...44,131,941
Ensembl chr11:44,099,753...44,131,937
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| G
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Ifnb1
|
interferon beta 1
|
multiple interactions
|
ISO
|
Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR1 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR2 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased phosphorylation of STAT4 protein]
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CTD |
PMID:17979888 |
|
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
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|
| G
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Ifng
|
interferon gamma
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multiple interactions increases secretion
|
ISO EXP
|
Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT1 protein]; Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT3 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IFNG mRNA] [Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; Curcumin inhibits the reaction [sodium arsenite affects the expression of IFNG mRNA]; tin protoporphyrin IX inhibits the reaction [[Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]] Curcumin results in increased secretion of IFNG protein Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
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CTD |
PMID:16782535 PMID:16867261 PMID:16959222 PMID:18006644 PMID:22714040 PMID:23452621 PMID:23942037 PMID:25541178 PMID:34047412 PMID:34272803 PMID:34470535 More...
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NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
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|
| G
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Ifnk
|
interferon kappa
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decreases expression
|
ISO
|
Curcumin results in decreased expression of IFNK mRNA
|
CTD |
PMID:18421014 |
|
NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:54,528,304...54,530,511
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|
| G
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Igf1
|
insulin-like growth factor 1
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decreases activity decreases expression multiple interactions decreases secretion
|
ISO
|
Curcumin results in decreased activity of IGF1 protein Curcumin analog results in decreased expression of IGF1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA] Curcumin results in decreased secretion of IGF1 protein Curcumin inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein]
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CTD |
PMID:17458902 PMID:17499312 PMID:18200517 PMID:26409325 |
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NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
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| G
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Igf1r
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insulin-like growth factor 1 receptor
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multiple interactions decreases expression
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ISO
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Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein]; Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of IGF1R protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein] Curcumin analog results in decreased expression of IGF1R mRNA; Curcumin results in decreased expression of IGF1R mRNA
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CTD |
PMID:17499312 PMID:17918158 PMID:26409325 |
|
NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
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| G
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Igf2
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insulin-like growth factor 2
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decreases expression multiple interactions
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ISO
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Curcumin analog results in decreased expression of IGF2 mRNA [arsenic trioxide co-treated with Curcumin] results in increased expression of IGF2 protein
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CTD |
PMID:26409325 PMID:27430728 |
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NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
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| G
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Igfbp1
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insulin-like growth factor binding protein 1
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multiple interactions
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ISO
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[arsenic trioxide co-treated with Curcumin] results in decreased expression of IGFBP1 protein
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CTD |
PMID:27430728 |
|
NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
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| G
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Igfbp2
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insulin-like growth factor binding protein 2
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multiple interactions
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ISO
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[arsenic trioxide co-treated with Curcumin] results in decreased expression of IGFBP2 protein
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CTD |
PMID:27430728 |
|
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
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| G
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Igfbp3
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insulin-like growth factor binding protein 3
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multiple interactions decreases expression increases secretion increases expression
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ISO EXP
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[arsenic trioxide co-treated with Curcumin] results in increased expression of IGFBP3 protein Curcumin results in decreased expression of IGFBP3 mRNA Curcumin results in increased secretion of IGFBP3 protein Curcumin results in increased expression of IGFBP3 mRNA
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CTD |
PMID:16101141 PMID:17499312 PMID:18299980 PMID:21594647 PMID:27430728 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
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| G
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Igfbp4
|
insulin-like growth factor binding protein 4
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multiple interactions
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ISO
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[arsenic trioxide co-treated with Curcumin] results in increased expression of IGFBP4 protein Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA]
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CTD |
PMID:18200517 PMID:27430728 |
|
NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
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|
| G
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Igfbp5
|
insulin-like growth factor binding protein 5
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA] [arsenic trioxide co-treated with Curcumin] results in increased expression of IGFBP5 protein
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CTD |
PMID:18200517 PMID:27430728 |
|
NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390
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| G
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Igfbp7
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insulin-like growth factor binding protein 7
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increases expression
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ISO
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Curcumin results in increased expression of IGFBP7 mRNA
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CTD |
PMID:21594647 |
|
NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620
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|
| G
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Ikbkb
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inhibitor of nuclear factor kappa B kinase subunit beta
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multiple interactions decreases activity
|
ISO
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Curcumin inhibits the reaction [bisphenol A results in increased expression of IKBKB protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]; Curcumin inhibits the reaction [TNF protein results in increased activity of IKBKB protein]; IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA] Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] Curcumin results in decreased activity of IKBKB protein
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CTD |
PMID:16023083 PMID:16219905 PMID:16678799 PMID:17965732 PMID:20054000 PMID:23452621 PMID:29793316 More...
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|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
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|
| G
|
Ikbkg
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inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
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multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IKBKG mRNA]
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CTD |
PMID:23452621 |
|
NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757
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|
| G
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Il10
|
interleukin 10
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multiple interactions decreases expression
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ISO EXP
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Curcumin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL10 mRNA]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein] Curcumin inhibits the reaction [Cisplatin results in decreased expression of IL10 protein] Curcumin results in decreased expression of IL10 protein CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]; Curcumin analog inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; Curcumin inhibits the reaction [Methotrexate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]
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CTD |
PMID:15604057 PMID:16867261 PMID:17979888 PMID:20885979 PMID:21397623 PMID:23452621 PMID:30016632 PMID:30431687 PMID:35549587 PMID:36178099 PMID:37955270 More...
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|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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|
| G
|
Il12a
|
interleukin 12A
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12A mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
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|
| G
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Il12b
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interleukin 12B
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multiple interactions
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EXP ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]
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CTD |
PMID:16867261 PMID:23452621 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
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|
| G
|
Il17a
|
interleukin 17A
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL17A protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA]; Curcumin inhibits the reaction [Cisplatin results in increased expression of IL17A protein]
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CTD |
PMID:34998855 PMID:35716765 PMID:36178099 |
|
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
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|
| G
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Il18
|
interleukin 18
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multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to IL18 promoter]]; Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to IL18 promoter]] Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL18 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL18 protein]; Curcumin inhibits the reaction [Atrazine results in increased expression of IL18 mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of IL18 protein] Curcumin results in decreased expression of IL18 mRNA Curcumin results in decreased expression of IL18 mRNA; Curcumin results in decreased expression of IL18 protein
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CTD |
PMID:16368150 PMID:16751071 PMID:17399992 PMID:35063475 PMID:38301994 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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|
| G
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Il1a
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interleukin 1 alpha
|
multiple interactions
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ISO EXP
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Curcumin inhibits the reaction [IL1A protein results in increased expression of TNFSF11 protein] Curcumin inhibits the reaction [Soot results in increased secretion of IL1A protein]
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CTD |
PMID:18719352 PMID:19782127 |
|
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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|
| G
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Il1b
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interleukin 1 beta
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multiple interactions affects expression decreases expression
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ISO EXP
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[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; Curcumin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Chloranil results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of IL1B protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL1B mRNA] Curcumin inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]; Curcumin inhibits the reaction [IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]]; Curcumin inhibits the reaction [IL1B protein results in decreased expression of GSK3B mRNA]; Curcumin inhibits the reaction [IL1B protein results in decreased expression of ITGB1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of A4GALT mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CTNNB1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGES protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of and results in increased localization of RELA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; Curcumin inhibits the reaction [TNF protein results in decreased expression of IL1B mRNA] Curcumin affects the expression of IL1B mRNA [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in increased expression of IL1B protein]; Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of IL1B mRNA]]; Curcumin analog inhibits the reaction [Monocrotaline results in increased expression of IL1B protein]; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased secretion of CXCL2 protein]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Curcumin inhibits the reaction [decamethrin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Ethanol results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Freund's Adjuvant results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Soot results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of IL1B protein]]
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CTD |
PMID:15604057 PMID:15793857 PMID:16751071 PMID:16782535 PMID:16819191 PMID:16867261 PMID:17151092 PMID:17273796 PMID:17291458 PMID:17383825 PMID:17887948 PMID:18001810 PMID:18200517 PMID:18368483 PMID:18549505 PMID:18752423 PMID:18946510 PMID:19782127 PMID:20712904 PMID:20816778 PMID:25123790 PMID:25541178 PMID:27393034 PMID:27645308 PMID:29315967 PMID:29571711 PMID:30016632 PMID:30098273 PMID:31407471 PMID:31454128 PMID:31712109 PMID:32718261 PMID:33350580 PMID:34272803 PMID:34470535 PMID:34719837 PMID:34998855 PMID:35063475 PMID:35817260 PMID:36156276 PMID:36178099 PMID:38056805 PMID:38301994 PMID:38369055 PMID:38698414 More...
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|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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| G
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Il1rl1
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interleukin 1 receptor-like 1
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Cisplatin results in increased expression of IL1RL1 protein]
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CTD |
PMID:36178099 |
|
NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891
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|
| G
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Il2
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interleukin 2
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multiple interactions
|
ISO
|
Curcumin results in decreased expression of and results in decreased secretion of IL2 protein
|
CTD |
PMID:19761891 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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|
| G
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Il23a
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interleukin 23 subunit alpha
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Cisplatin results in increased expression of IL23A protein]
|
CTD |
PMID:36178099 |
|
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
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| G
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Il2ra
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interleukin 2 receptor subunit alpha
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multiple interactions
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EXP
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Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL2RA protein]
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CTD |
PMID:18340409 |
|
NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507
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|
| G
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Il4
|
interleukin 4
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multiple interactions decreases expression
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EXP ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein] Curcumin results in decreased expression of IL4 protein
|
CTD |
PMID:16782535 PMID:16867261 PMID:21397623 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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|
| G
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Il5
|
interleukin 5
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multiple interactions
|
ISO
|
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL5 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL5 protein]
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CTD |
PMID:34998855 |
|
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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|
| G
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Il6
|
interleukin 6
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multiple interactions decreases expression increases expression affects expression
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ISO EXP
|
Curcumin inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [[benz(a)anthracene co-treated with TNF protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Acids results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Acids results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of IL6 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR protein]; Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; Curcumin inhibits the reaction [TNF protein results in decreased expression of IL6 mRNA]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]] [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of IL6 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Chloranil results in increased expression of IL6 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of IL6 protein]; Curcumin inhibits the reaction [sodium arsenite affects the expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL6 mRNA] Curcumin results in increased expression of IL6 protein Curcumin results in increased expression of IL6 mRNA [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in increased expression of IL6 protein]; [Zinc binds to Curcumin] inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]; Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of IL6 protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Colistin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Curcumin inhibits the reaction [decamethrin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Freund's Adjuvant results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of IL6 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Soot results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 protein]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]] Curcumin affects the expression of IL6 mRNA; Curcumin affects the expression of IL6 protein
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CTD |
PMID:16751071 PMID:17151092 PMID:17273796 PMID:17383825 PMID:17999991 PMID:18006644 PMID:18025290 PMID:18200517 PMID:18209571 PMID:18357586 PMID:18379247 PMID:18549505 PMID:18676361 PMID:18752423 PMID:19074641 PMID:19782127 PMID:20712904 PMID:21397623 PMID:21594647 PMID:21811692 PMID:22142850 PMID:22465177 PMID:22683883 PMID:23396138 PMID:24760747 PMID:25123790 PMID:25387343 PMID:28063877 PMID:28700904 PMID:28951138 PMID:29480285 PMID:29571711 PMID:29793316 PMID:30016632 PMID:30138604 PMID:31199764 PMID:31454128 PMID:31820278 PMID:33350580 PMID:33952798 PMID:34042043 PMID:34272803 PMID:34577062 PMID:34787501 PMID:35549587 PMID:35716765 PMID:35817260 PMID:37955270 PMID:38056805 PMID:38698414 More...
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|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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| G
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Il6r
|
interleukin 6 receptor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trichloroethylene results in increased expression of IL6R protein]
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CTD |
PMID:34233590 |
|
NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
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| G
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Il6st
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interleukin 6 cytokine family signal transducer
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trichloroethylene results in increased expression of IL6ST protein]
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CTD |
PMID:34233590 |
|
NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182
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| G
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Ins1
|
insulin 1
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multiple interactions
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EXP ISO
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Curcumin inhibits the reaction [Lamotrigine results in increased expression of INS1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] Curcumin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]
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CTD |
PMID:23267840 PMID:25541178 PMID:27208389 PMID:38050455 |
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
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| G
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Ins2
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insulin 2
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multiple interactions
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EXP ISO
|
Curcumin inhibits the reaction [Fructose results in increased expression of INS protein] Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]]
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CTD |
PMID:25268984 PMID:26713546 PMID:28595985 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
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| G
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Insig2
|
insulin induced gene 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA]
|
CTD |
PMID:18704882 |
|
NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658
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|
| G
|
Insr
|
insulin receptor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in decreased expression of INSR protein modified form]
|
CTD |
PMID:29793316 |
|
NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
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|
| G
|
Irag2
|
inositol 1,4,5-triphosphate receptor associated 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of IRAG2 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 4:179,819,526...179,874,408
Ensembl chr 4:179,820,188...179,874,406
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|
| G
|
Irak1
|
interleukin-1 receptor-associated kinase 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of IRAK1 protein] Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IRAK1 mRNA]
|
CTD |
PMID:16678799 PMID:23452621 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
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|
| G
|
Irak2
|
interleukin-1 receptor-associated kinase 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IRAK2 mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210
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|
| G
|
Irf3
|
interferon regulatory factor 3
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of IRF3 protein]
|
CTD |
PMID:16678799 |
|
NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401
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|
| G
|
Irf5
|
interferon regulatory factor 5
|
increases expression
|
ISO
|
Curcumin analog results in increased expression of IRF5 mRNA
|
CTD |
PMID:26409325 |
|
NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:59,081,357...59,112,552
|
|
| G
|
Irs1
|
insulin receptor substrate 1
|
multiple interactions affects phosphorylation
|
EXP ISO
|
Curcumin inhibits the reaction [Fructose affects the phosphorylation of IRS1 protein] Curcumin inhibits the reaction [bisphenol A results in increased expression of IRS1 protein modified form] Curcumin affects the phosphorylation of IRS1 protein
|
CTD |
PMID:26713546 PMID:27208389 PMID:29793316 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
|
|
| G
|
Irs2
|
insulin receptor substrate 2
|
affects phosphorylation
|
ISO
|
Curcumin affects the phosphorylation of IRS2 protein
|
CTD |
PMID:27208389 |
|
NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
|
|
| G
|
Itga2b
|
integrin subunit alpha 2b
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [F2 protein results in increased expression of ITGA2B protein]
|
CTD |
PMID:18565277 |
|
NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833
|
|
| G
|
Itgam
|
integrin subunit alpha M
|
multiple interactions increases expression
|
ISO
|
Calcitriol promotes the reaction [Curcumin results in increased expression of ITGAM]; Tretinoin promotes the reaction [Curcumin results in increased expression of ITGAM]
|
CTD |
PMID:9112257 |
|
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
|
|
| G
|
Itgb1
|
integrin subunit beta 1
|
multiple interactions increases expression
|
ISO
|
Curcumin inhibits the reaction [IL1B protein results in decreased expression of ITGB1 protein] Curcumin results in increased expression of ITGB1 protein
|
CTD |
PMID:17291458 |
|
NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
|
|
| G
|
Itgb3
|
integrin subunit beta 3
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [F2 protein results in increased expression of ITGB3 protein]
|
CTD |
PMID:18565277 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
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|
| G
|
Itm2a
|
integral membrane protein 2A
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr X:76,559,183...76,565,144
Ensembl chr X:76,559,181...76,565,437
|
|
| G
|
Ivl
|
involucrin
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [MAP3K1 protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [PRKCD protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [PRKCE protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [PRKCH protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA]
|
CTD |
PMID:17148446 |
|
NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578
|
|
| G
|
Jak2
|
Janus kinase 2
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of JAK2 protein Arsenic Trioxide promotes the reaction [Curcumin results in decreased expression of JAK2 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased phosphorylation of JAK2 protein]
|
CTD |
PMID:16959222 PMID:34233590 PMID:36352148 |
|
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
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|
| G
|
Jak3
|
Janus kinase 3
|
decreases activity
|
ISO
|
Curcumin results in decreased activity of JAK3 protein
|
CTD |
PMID:16932349 |
|
NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
decreases phosphorylation multiple interactions increases expression decreases activity
|
ISO EXP
|
Curcumin results in decreased phosphorylation of JUN protein Curcumin inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Curcumin inhibits the reaction [benzyl isothiocyanate results in increased expression of and results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of JUN mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein] Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [Cisplatin results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of JUN protein] Curcumin results in increased expression of JUN mRNA [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Curcumin analog inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein] Curcumin results in decreased activity of JUN protein
|
CTD |
PMID:11035063 PMID:15713895 PMID:17148446 PMID:17458902 PMID:17596214 PMID:17827730 PMID:18628248 PMID:23452621 PMID:26191140 PMID:27535828 PMID:31587482 PMID:35716765 PMID:36178099 More...
|
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Junb
|
JunB proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases ubiquitination
|
ISO
|
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein] Curcumin results in increased ubiquitination of JUNB protein
|
CTD |
PMID:17148446 |
|
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
|
|
| G
|
Jund
|
JunD proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein]
|
CTD |
PMID:17148446 |
|
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
|
|
| G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases activity
|
ISO
|
Curcumin results in decreased activity of KCNH2 protein
|
CTD |
PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
|
|
| G
|
Kcnmb2
|
potassium calcium-activated channel subfamily M regulatory beta subunit 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of KCNMB2 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 2:116,598,511...116,903,886
Ensembl chr 2:116,599,387...116,903,854
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|
| G
|
Kdr
|
kinase insert domain receptor
|
multiple interactions affects expression
|
ISO EXP
|
[bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of KDR protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of KDR protein] Curcumin affects the expression of KDR mRNA Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein] Curcumin inhibits the reaction [Dietary Fats results in increased expression of KDR mRNA]
|
CTD |
PMID:17960570 PMID:19297423 PMID:23845850 PMID:35752269 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
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|
| G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 protein]; KEAP1 protein inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA] Curcumin results in decreased expression of KEAP1 mRNA Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 mRNA]; Curcumin inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein] Curcumin analog results in decreased expression of KEAP1 protein; Curcumin results in decreased expression of KEAP1 protein Curcumin analog promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 protein]; Curcumin inhibits the reaction [Gentamicins results in increased expression of KEAP1 mRNA]; Curcumin promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein] Curcumin results in increased expression of KEAP1 mRNA
|
CTD |
PMID:17535857 PMID:23710286 PMID:26991801 PMID:30946834 PMID:31521693 PMID:34758851 PMID:35063475 PMID:36037877 PMID:37741124 PMID:38056816 More...
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|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
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|
| G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
multiple interactions
|
EXP
|
[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of KIT protein]; [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of KIT protein
|
CTD |
PMID:26612707 |
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
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|
| G
|
Klf10
|
KLF transcription factor 10
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of KLF10 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
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|
| G
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Klf6
|
KLF transcription factor 6
|
increases expression
|
ISO
|
Curcumin results in increased expression of KLF6 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
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|
| G
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Klhl21
|
kelch-like family member 21
|
increases expression
|
ISO
|
Curcumin results in increased expression of KLHL21 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 5:167,797,621...167,806,276
Ensembl chr 5:167,797,591...167,806,276
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|
| G
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Klhl24
|
kelch-like family member 24
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of KLHL24 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050
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|
| G
|
Klk1c10
|
kallikrein 1-related peptidase C10
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of KLK3 mRNA; Curcumin results in decreased expression of KLK3 protein Curcumin inhibits the reaction [AR protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [EP300 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [GATA2 protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 protein]; Curcumin inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [Metribolone results in increased expression of KLK3 protein]; Curcumin results in decreased expression of and results in decreased secretion of KLK3 protein; trichostatin A inhibits the reaction [Curcumin results in decreased expression of KLK3 mRNA]
|
CTD |
PMID:12497104 PMID:18676361 PMID:18719366 PMID:21134073 PMID:22258452 |
|
NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
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|
| G
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Kmt5a
|
lysine methyltransferase 5A
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of KMT5A mRNA; Curcumin results in decreased expression of KMT5A protein
|
CTD |
PMID:25256401 |
|
NCBI chr12:37,800,339...37,823,706
Ensembl chr12:37,800,344...37,823,783
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|
| G
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Kras
|
KRAS proto-oncogene, GTPase
|
decreases expression multiple interactions
|
ISO
|
Curcumin analog results in decreased expression of KRAS mRNA; Curcumin results in decreased expression of KRAS mRNA Curcumin affects the reaction [KRAS protein affects the localization of TRP53 protein]; Curcumin inhibits the reaction [KRAS protein results in decreased expression of XPO1 protein]
|
CTD |
PMID:17041101 PMID:21519798 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
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|
| G
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Krtap2-1
|
keratin associated protein 2-1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of KRTAP2-1 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr10:85,068,302...85,068,694
|
|
| G
|
Kynu
|
kynureninase
|
increases expression
|
ISO
|
Curcumin results in increased expression of KYNU mRNA
|
CTD |
PMID:18421014 |
|
NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014
|
|
| G
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Lamp1
|
lysosomal-associated membrane protein 1
|
affects expression multiple interactions
|
EXP ISO
|
Curcumin affects the expression of LAMP1 mRNA Curcumin promotes the reaction [sodium arsenite results in increased expression of LAMP1 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of LAMP1 protein]]
|
CTD |
PMID:18539377 PMID:34758851 |
|
NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159
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|
| G
|
Lbp
|
lipopolysaccharide binding protein
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
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|
| G
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Lcn2
|
lipocalin 2
|
multiple interactions
|
ISO EXP
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA] Curcumin inhibits the reaction [Cadmium Chloride results in increased export of LCN2 protein]; Curcumin inhibits the reaction [Gentamicins results in increased expression of LCN2 mRNA]; Curcumin inhibits the reaction [maleic acid results in increased secretion of LCN2 protein]
|
CTD |
PMID:18200517 PMID:25119790 PMID:29421648 PMID:38056816 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
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|
| G
|
Lcp1
|
lymphocyte cytosolic protein 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092
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|
| G
|
Lcp2
|
lymphocyte cytosolic protein 2
|
increases expression
|
ISO
|
Curcumin results in increased expression of LCP2 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr10:19,146,846...19,193,750
Ensembl chr10:19,146,554...19,193,744
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|
| G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions decreases expression
|
ISO EXP
|
ATF4 inhibits the reaction [Curcumin results in decreased expression of LDHA protein]; Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of LDHA protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of LDHA protein] Curcumin inhibits the reaction [Gentamicins results in increased expression of LDHA protein]
|
CTD |
PMID:36640941 PMID:36924976 PMID:38056816 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
multiple interactions affects expression increases expression
|
ISO
|
Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA]; Curcumin results in increased expression of and results in increased activity of LDLR protein Curcumin affects the expression of LDLR mRNA Curcumin results in increased expression of LDLR mRNA; Curcumin results in increased expression of LDLR protein
|
CTD |
PMID:16713233 PMID:16963807 PMID:18704882 PMID:27208389 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Lef1
|
lymphoid enhancer binding factor 1
|
increases expression multiple interactions
|
EXP
|
Curcumin results in increased expression of LEF1 mRNA Curcumin inhibits the reaction [bisphenol A results in decreased expression of LEF1 mRNA]
|
CTD |
PMID:25963729 |
|
NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929
|
|
| G
|
Lgmn
|
legumain
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328
|
|
| G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]
|
CTD |
PMID:31199764 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
| G
|
Lhx5
|
LIM homeobox 5
|
affects expression
|
EXP
|
Curcumin affects the expression of LHX5 mRNA
|
CTD |
PMID:18539377 |
|
NCBI chr12:41,786,746...41,795,183
Ensembl chr12:41,786,746...41,795,183
|
|
| G
|
Lig3
|
DNA ligase 3
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG3 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG3 protein]
|
CTD |
PMID:21332098 |
|
NCBI chr10:68,215,371...68,238,705
Ensembl chr10:68,215,407...68,238,704
|
|
| G
|
Lig4
|
DNA ligase 4
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG4 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG4 protein]
|
CTD |
PMID:21332098 |
|
NCBI chr16:86,220,345...86,228,930
Ensembl chr16:86,220,279...86,229,926
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| G
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Lipc
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lipase C, hepatic type
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affects expression
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ISO
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Curcumin affects the expression of LIPC mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285
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| G
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Lox
|
lysyl oxidase
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA]
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CTD |
PMID:18200517 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
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| G
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Lpar1
|
lysophosphatidic acid receptor 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of LPAR1 mRNA
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CTD |
PMID:17999991 |
|
NCBI chr 5:78,024,139...78,147,071
Ensembl chr 5:78,024,139...78,142,188
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| G
|
Lpl
|
lipoprotein lipase
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affects expression
|
ISO
|
Curcumin affects the expression of LPL mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
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| G
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Lrp5
|
LDL receptor related protein 5
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multiple interactions increases expression
|
EXP
|
Curcumin inhibits the reaction [bisphenol A results in decreased expression of LRP5 mRNA] Curcumin results in increased expression of LRP5 mRNA
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CTD |
PMID:25963729 |
|
NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822
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|
| G
|
Lrp6
|
LDL receptor related protein 6
|
multiple interactions increases expression
|
EXP
|
Curcumin inhibits the reaction [bisphenol A results in decreased expression of LRP6 mRNA] Curcumin results in increased expression of LRP6 mRNA
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CTD |
PMID:25963729 |
|
NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716
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| G
|
Lrrn3
|
leucine rich repeat neuronal 3
|
increases expression
|
ISO
|
Curcumin results in increased expression of LRRN3 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 6:64,216,164...64,247,293
Ensembl chr 6:64,215,878...64,247,614
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|
| G
|
Lss
|
lanosterol synthase
|
affects expression decreases expression
|
ISO EXP
|
Curcumin affects the expression of LSS mRNA Curcumin results in decreased expression of LSS mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253
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| G
|
Lta
|
lymphotoxin alpha
|
decreases expression multiple interactions increases expression
|
ISO
|
Curcumin results in decreased expression of LTA mRNA [arsenic trioxide co-treated with Curcumin] results in increased expression of LTA protein Curcumin results in increased expression of LTA mRNA
|
CTD |
PMID:16101141 PMID:17198877 PMID:27430728 |
|
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
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|
| G
|
Ltb
|
lymphotoxin beta
|
increases expression decreases expression
|
ISO
|
Curcumin results in increased expression of LTB mRNA Curcumin results in decreased expression of LTB mRNA
|
CTD |
PMID:16751071 PMID:17198877 |
|
NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
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|
| G
|
Ltbr
|
lymphotoxin beta receptor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of LTBR mRNA]
|
CTD |
PMID:23452621 |
|
NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296
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|
| G
|
Lyz2
|
lysozyme 2
|
multiple interactions affects expression
|
ISO EXP
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA] Curcumin affects the expression of LYZ2 mRNA
|
CTD |
PMID:18200517 PMID:18539377 |
|
NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011
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|
| G
|
Madcam1
|
mucosal vascular addressin cell adhesion molecule 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 7:10,686,920...10,690,322
Ensembl chr 7:10,686,250...10,690,322
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|
| G
|
Maoa
|
monoamine oxidase A
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631
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|
| G
|
Map1lc3a
|
microtubule-associated protein 1 light chain 3 alpha
|
multiple interactions
|
ISO
|
Curcumin promotes the reaction [sodium arsenite results in increased lipidation of and results in increased localization of MAP1LC3A protein]
|
CTD |
PMID:38141737 |
|
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
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|
| G
|
Map1lc3b
|
microtubule-associated protein 1 light chain 3 beta
|
increases lipidation multiple interactions increases localization decreases expression increases expression
|
ISO EXP
|
Curcumin results in increased lipidation of MAP1LC3B protein Curcumin promotes the reaction [sodium arsenite results in increased lipidation of and results in increased localization of MAP1LC3B protein] MIR206 affects the reaction [Curcumin results in increased lipidation of MAP1LC3B protein] Curcumin results in increased localization of MAP1LC3B protein Curcumin results in decreased expression of MAP1LC3B protein Curcumin results in increased expression of MAP1LC3B mRNA 3-methyladenine inhibits the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; 3-nitropropionic acid inhibits the reaction [Curcumin results in increased localization of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; Curcumin inhibits the reaction [4-phenylbutyric acid results in decreased expression of MAP1LC3B protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of MAP1LC3B protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of MAP1LC3B protein]; Sirolimus promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; U 0126 inhibits the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]
|
CTD |
PMID:34634291 PMID:36640941 PMID:37634662 PMID:38141737 PMID:38764151 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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|
| G
|
Map2k1
|
mitogen activated protein kinase kinase 1
|
multiple interactions
|
ISO
|
MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; MAP2K1 results in decreased susceptibility to [Curcumin co-treated with Mitomycin]
|
CTD |
PMID:21810436 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
|
|
| G
|
Map2k2
|
mitogen activated protein kinase kinase 2
|
multiple interactions
|
ISO
|
MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; MAP2K2 results in decreased susceptibility to [Curcumin co-treated with Mitomycin]
|
CTD |
PMID:21810436 |
|
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
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|
| G
|
Map2k3
|
mitogen activated protein kinase kinase 3
|
increases expression
|
ISO
|
Curcumin results in increased expression of MAP2K3 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004
|
|
| G
|
Map2k4
|
mitogen activated protein kinase kinase 4
|
decreases expression increases phosphorylation
|
ISO
|
Curcumin results in decreased expression of MAP2K4 mRNA Curcumin increases phosphorylation of MAP2K4 protein in uterine cervix
|
CTD RGD |
PMID:15713895 PMID:25198898 |
RGD:150429751 |
NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185
|
|
| G
|
Map3k1
|
mitogen-activated protein kinase kinase kinase 1
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [MAP3K1 protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of MAP3K1 mRNA] Curcumin results in decreased expression of MAP3K1 mRNA
|
CTD |
PMID:15713895 PMID:17148446 PMID:23452621 |
|
NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897
|
|
| G
|
Map3k5
|
mitogen-activated protein kinase kinase kinase 5
|
multiple interactions increases phosphorylation
|
ISO
|
Curcumin inhibits the reaction [Cisplatin results in increased phosphorylation of MAP3K5 protein] Curcumin increases phosphorylation of MAP3K5 protein in uterine cervix
|
CTD RGD |
PMID:36178099 PMID:25198898 |
RGD:150429751 |
NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898
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|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions decreases phosphorylation increases phosphorylation decreases expression decreases activity
|
ISO EXP
|
[bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK1 protein]; [Curcumin results in decreased activity of MAPK1 protein] which results in increased susceptibility to Cisplatin; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Acids results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [bromopyruvate results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Furazolidone results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAPK1 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]; rottlerin inhibits the reaction [Curcumin results in increased expression of MAPK1 protein]; U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein]; U 0126 promotes the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]] Curcumin inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Fructose results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK1 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]] [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; [piperlongumine co-treated with Curcumin] results in decreased activity of MAPK1 protein; Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of MAPK1 protein] Curcumin results in decreased expression of MAPK1 protein
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CTD |
PMID:11035063 PMID:11981161 PMID:16934299 PMID:17372590 PMID:17535857 PMID:17965732 PMID:18214481 PMID:18316600 PMID:18321868 PMID:18332871 PMID:18357586 PMID:18555241 PMID:18784349 PMID:19074641 PMID:19175364 PMID:19383353 PMID:19501152 PMID:20605902 PMID:20727180 PMID:21493726 PMID:21810436 PMID:22142850 PMID:24307199 PMID:25866362 PMID:26191140 PMID:26713546 PMID:27996348 PMID:29723552 PMID:31081568 PMID:33617879 PMID:34272803 PMID:34634291 PMID:35752269 PMID:38141737 More...
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|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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|
| G
|
Mapk10
|
mitogen activated protein kinase 10
|
multiple interactions
|
EXP
|
Curcumin analog inhibits the reaction [Rotenone results in increased phosphorylation of MAPK10 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK10 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK10 protein]
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CTD |
PMID:24952339 PMID:27535828 PMID:27966075 |
|
NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100
|
|
| G
|
Mapk11
|
mitogen-activated protein kinase 11
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK11 protein]
|
CTD |
PMID:38141737 |
|
NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038
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|
| G
|
Mapk12
|
mitogen-activated protein kinase 12
|
increases activity multiple interactions
|
ISO
|
Curcumin results in increased activity of MAPK12 protein Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK12 protein]
|
CTD |
PMID:21594647 PMID:38141737 |
|
NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307
|
|
| G
|
Mapk13
|
mitogen activated protein kinase 13
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK13 protein]
|
CTD |
PMID:38141737 |
|
NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191
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|
| G
|
Mapk14
|
mitogen activated protein kinase 14
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK14 protein] Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK14 mRNA]; MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]
|
CTD |
PMID:17151092 PMID:18357586 PMID:31521693 PMID:38141737 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions decreases phosphorylation increases phosphorylation decreases expression decreases activity
|
ISO EXP
|
[bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK3 protein]; [Curcumin results in decreased activity of MAPK3 protein] which results in increased susceptibility to Cisplatin; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK3 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Acids results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [bromopyruvate results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; rottlerin inhibits the reaction [Curcumin results in increased expression of MAPK3 protein]; U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein]; U 0126 promotes the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]] Curcumin inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Fructose results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK3 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]] [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; [piperlongumine co-treated with Curcumin] results in decreased activity of MAPK3 protein; Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Cisplatin results in decreased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of MAPK3 protein] Curcumin results in decreased expression of MAPK3 protein
|
CTD |
PMID:11035063 PMID:11981161 PMID:16934299 PMID:17372590 PMID:17535857 PMID:17965732 PMID:18214481 PMID:18316600 PMID:18321868 PMID:18332871 PMID:18357586 PMID:18555241 PMID:18784349 PMID:19074641 PMID:19175364 PMID:19383353 PMID:19501152 PMID:20605902 PMID:20727180 PMID:21493726 PMID:21810436 PMID:22142850 PMID:24307199 PMID:25866362 PMID:26191140 PMID:26713546 PMID:29723552 PMID:31081568 PMID:33617879 PMID:34272803 PMID:34634291 PMID:35752269 PMID:36178099 PMID:38141737 More...
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|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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|
| G
|
Mapk8
|
mitogen-activated protein kinase 8
|
increases phosphorylation multiple interactions decreases phosphorylation increases expression
|
ISO EXP
|
Curcumin increases phosphorylation of MAPK8 protein in uterine cervix Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK8 mRNA]; Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein]; MAPK8 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA] Curcumin results in decreased phosphorylation of MAPK8 protein Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK8 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK8 protein Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] Curcumin results in increased expression of MAPK8 mRNA Curcumin results in increased phosphorylation of MAPK8 protein
|
CTD RGD |
PMID:11981161 PMID:16101141 PMID:16678799 PMID:16934299 PMID:17372590 PMID:18316600 PMID:18321868 PMID:18332871 PMID:20727180 PMID:24952339 PMID:27966075 PMID:31081568 PMID:31521693 PMID:34272803 PMID:34634291 PMID:35716765 PMID:36178099 PMID:38141737 PMID:25198898 More...
|
RGD:150429751 |
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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|
| G
|
Mapk9
|
mitogen-activated protein kinase 9
|
multiple interactions decreases phosphorylation increases phosphorylation
|
ISO EXP
|
Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK9 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein] Curcumin results in decreased phosphorylation of MAPK9 protein Curcumin results in increased phosphorylation of MAPK9 protein Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK9 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK9 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK9 protein
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CTD |
PMID:11981161 PMID:17372590 PMID:18316600 PMID:18321868 PMID:18332871 PMID:24952339 PMID:27966075 PMID:34272803 More...
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|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
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|
| G
|
Mapt
|
microtubule-associated protein tau
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA]
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CTD |
PMID:31521693 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
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|
| G
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Marchf6
|
membrane associated ring-CH-type finger 6
|
increases expression
|
ISO
|
Curcumin results in increased expression of MARCHF6 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:84,166,570...84,243,792
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|
| G
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Mcl1
|
MCL1 apoptosis regulator, BCL2 family member
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of MCL1 protein alternative form [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of MCL1 protein
|
CTD |
PMID:18829502 PMID:34675983 |
|
NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
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|
| G
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Mcm2
|
minichromosome maintenance complex component 2
|
decreases expression
|
EXP
|
Curcumin results in decreased expression of MCM2 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
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|
| G
|
Mcm7
|
minichromosome maintenance complex component 7
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MCM7 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771
|
|
| G
|
Mdm2
|
MDM2 proto-oncogene
|
decreases expression increases expression multiple interactions
|
ISO
|
[Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA; Curcumin results in decreased expression of MDM2 mRNA; Curcumin results in decreased expression of MDM2 protein Curcumin analog results in increased expression of MDM2 mRNA Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of MDM2 protein]
|
CTD |
PMID:17332326 PMID:24831732 PMID:26409325 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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|
| G
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Mecp2
|
methyl CpG binding protein 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MECP2 protein
|
CTD |
PMID:23593078 |
|
NCBI chr X:156,932,481...156,995,981
Ensembl chr X:156,941,234...156,943,560
|
|
| G
|
Mef2c
|
myocyte enhancer factor 2C
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MEF2C mRNA
|
CTD |
PMID:27237783 |
|
NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640
|
|
| G
|
Meltf
|
melanotransferrin
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MELTF mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr11:82,389,420...82,411,270
Ensembl chr11:82,389,420...82,411,270
|
|
| G
|
Mfn1
|
mitofusin 1
|
increases expression
|
EXP
|
Curcumin results in increased expression of MFN1 protein
|
CTD |
PMID:28698153 |
|
NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190
|
|
| G
|
Mfng
|
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
increases expression
|
ISO
|
Curcumin results in increased expression of MFNG mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 7:112,191,288...112,209,129
Ensembl chr 7:112,161,071...112,209,129
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
decreases expression increases expression decreases activity multiple interactions
|
ISO
|
Curcumin results in decreased expression of MGMT mRNA Curcumin results in increased expression of MGMT mRNA Curcumin results in decreased activity of MGMT protein Curcumin results in increased expression of and results in increased activity of MGMT protein
|
CTD |
PMID:16950796 PMID:17596214 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
increases expression
|
EXP
|
Curcumin results in increased expression of MGST1 mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
|
|
| G
|
Mir125a
|
microRNA 125a
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of MIR125A mRNA Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of MIR125A mRNA]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of TNF protein]]
|
CTD |
PMID:29723631 PMID:33952798 |
|
NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759
|
|
| G
|
Mir146a
|
microRNA 146a
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA]
|
CTD |
PMID:22099153 |
|
NCBI chr10:28,349,996...28,350,090
|
|
| G
|
Mir19a
|
microRNA 19a
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of MIR19A mRNA]
|
CTD |
PMID:24831732 |
|
NCBI chr15:98,588,131...98,588,212
Ensembl chr15:98,588,131...98,588,212
|
|
| G
|
Mir206
|
microRNA 206
|
increases expression multiple interactions
|
EXP
|
Curcumin results in increased expression of MIR206 mRNA MIR206 affects the reaction [Curcumin results in decreased expression of SQSTM1 protein]; MIR206 affects the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; MIR206 affects the reaction [Curcumin results in decreased phosphorylation of MTOR protein]; MIR206 affects the reaction [Curcumin results in increased expression of BECN1 protein]; MIR206 affects the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]
|
CTD |
PMID:38764151 |
|
NCBI chr 9:30,590,697...30,590,780
Ensembl chr 9:30,590,697...30,590,780
|
|
| G
|
Mir21
|
microRNA 21
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MIR21 mRNA
|
CTD |
PMID:29723631 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
|
Mir22
|
microRNA 22
|
increases expression
|
ISO
|
Curcumin results in increased expression of MIR22
|
CTD |
PMID:26244872 |
|
NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425
|
|
| G
|
Mir222
|
microRNA 222
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MIR222 mRNA
|
CTD |
PMID:29723631 |
|
NCBI chr X:6,022,621...6,022,723
Ensembl chr X:6,022,621...6,022,723
|
|
| G
|
Mir223
|
microRNA 223
|
increases expression
|
ISO
|
Curcumin results in increased expression of MIR223 mRNA
|
CTD |
PMID:29723631 |
|
NCBI chr X:65,151,383...65,151,492
Ensembl chr X:65,151,383...65,151,492
|
|
| G
|
Mir27a
|
microRNA 27a
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MIR27A mRNA
|
CTD |
PMID:29723631 |
|
NCBI chr19:40,859,603...40,859,689
|
|
| G
|
Mir27b
|
microRNA 27b
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MIR27B mRNA
|
CTD |
PMID:29723631 |
|
NCBI chr17:1,819,147...1,819,243
|
|
| G
|
Mir30a
|
microRNA 30a
|
increases expression
|
ISO
|
Curcumin results in increased expression of MIR30A mRNA
|
CTD |
PMID:29723631 |
|
NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011
|
|
| G
|
Mir34a
|
microRNA 34a
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Cyclosporine results in increased expression of MIR34A mRNA]
|
CTD |
PMID:32569592 |
|
NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053
|
|
| G
|
Mir532
|
microRNA 532
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of MIR532 mRNA MIR532 affects the reaction [Curcumin results in decreased expression of AKT3 protein]; MIR532 affects the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; NRIP1 mRNA alternative form inhibits the reaction [Curcumin results in increased expression of MIR532 mRNA]
|
CTD |
PMID:37471645 |
|
NCBI chr X:17,919,185...17,919,263
Ensembl chr X:17,919,185...17,919,263
|
|
| G
|
Mir802
|
microRNA 802
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Acetaminophen results in increased expression of MIR802 mRNA]
|
CTD |
PMID:33350580 |
|
NCBI chr11:46,112,362...46,112,457
Ensembl chr11:46,112,362...46,112,457
|
|
| G
|
Mir99a
|
microRNA 99a
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [benzyl isothiocyanate results in increased expression of MIR99A mRNA]
|
CTD |
PMID:31587482 |
|
NCBI chr11:29,687,392...29,687,472
Ensembl chr11:29,687,392...29,687,472
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
multiple interactions decreases expression
|
ISO EXP
|
[Curcumin co-treated with Gemcitabine] results in decreased expression of MKI67 protein Curcumin inhibits the reaction [Lamotrigine results in decreased expression of MKI67 protein] Curcumin results in decreased expression of MKI67 protein
|
CTD |
PMID:17440100 PMID:18226269 PMID:19372569 PMID:38050455 PMID:38348716 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mme
|
membrane metallo-endopeptidase
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MME mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463
|
|
| G
|
Mmp1
|
matrix metallopeptidase 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]
|
CTD |
PMID:30098273 |
|
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
|
|
| G
|
Mmp10
|
matrix metallopeptidase 10
|
increases expression
|
ISO
|
Curcumin results in increased expression of MMP10 mRNA
|
CTD |
PMID:15713895 |
|
NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613
|
|
| G
|
Mmp13
|
matrix metallopeptidase 13
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Chloramphenicol results in increased expression of MMP13 mRNA]
|
CTD |
PMID:20338993 |
|
NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
|
|
| G
|
Mmp14
|
matrix metallopeptidase 14
|
decreases expression multiple interactions
|
ISO EXP
|
Curcumin results in decreased expression of MMP14 protein Curcumin inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein] Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA]
|
CTD |
PMID:16934674 PMID:18200517 PMID:18495463 |
|
NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
|
|
| G
|
Mmp2
|
matrix metallopeptidase 2
|
decreases expression multiple interactions decreases activity increases activity
|
ISO EXP
|
Curcumin results in decreased expression of MMP2 protein Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of MMP2 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of MMP2 protein]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of and results in increased activity of MMP2 protein]; Curcumin inhibits the reaction [VIP protein results in increased activity of MMP2 protein]; Curcumin results in decreased secretion of and results in decreased activity of MMP2 protein modified form; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of MMP2 protein] Curcumin results in decreased activity of MMP2 protein Curcumin results in increased activity of MMP2 protein Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA] 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased activity of MMP2 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein]
|
CTD |
PMID:16934674 PMID:17531121 PMID:17996675 PMID:18200517 PMID:18226269 PMID:18495463 PMID:19189304 PMID:22771723 PMID:25447407 PMID:35716765 PMID:36640941 More...
|
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
|
|
| G
|
Mmp3
|
matrix metallopeptidase 3
|
increases expression
|
ISO
|
Curcumin results in increased expression of MMP3 mRNA
|
CTD |
PMID:15713895 PMID:18321735 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
| G
|
Mmp7
|
matrix metallopeptidase 7
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [epigallocatechin gallate results in increased expression of MMP7 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of MMP7 mRNA]; Curcumin inhibits the reaction [Tretinoin results in increased expression of MMP7 mRNA]
|
CTD |
PMID:17928719 PMID:23452621 |
|
NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions decreases activity decreases expression increases activity affects expression
|
ISO EXP
|
3-caffeoyl-4-dihydrocaffeoylquinic acid promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [VIP protein results in increased activity of MMP9 protein]; Curcumin promotes the reaction [3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Curcumin results in decreased secretion of and results in decreased activity of MMP9 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of MMP9 protein] Curcumin results in decreased activity of MMP9 protein Curcumin results in increased activity of MMP9 protein Curcumin affects the expression of MMP9 mRNA; Curcumin affects the expression of MMP9 protein 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased activity of MMP9 protein]; [Zinc binds to Curcumin] inhibits the reaction [Acetic Acid results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Ethanol results in increased expression of MMP9 mRNA] [Curcumin co-treated with Gemcitabine] results in decreased expression of MMP9 protein; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]
|
CTD |
PMID:16219905 PMID:16243823 PMID:17291458 PMID:17440100 PMID:17531121 PMID:17640567 PMID:17887948 PMID:17996675 PMID:18226269 PMID:18379247 PMID:18495463 PMID:18628248 PMID:18829502 PMID:19189304 PMID:20152819 PMID:20599481 PMID:21354279 PMID:22771723 PMID:23933360 PMID:24211270 PMID:25656647 PMID:26514923 PMID:34998855 PMID:35716765 PMID:36640941 More...
|
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mphosph6
|
M phase phosphoprotein 6
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of MPHOSPH6 mRNA
|
CTD |
PMID:18421014 |
|
NCBI chr19:62,768,909...62,778,874
Ensembl chr19:62,768,909...62,778,950
|
|
| G
|
Mpo
|
myeloperoxidase
|
multiple interactions decreases activity
|
EXP ISO
|
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein]; Curcumin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Curcumin inhibits the reaction [Methotrexate results in increased expression of MPO protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of MPO protein]] [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of MPO protein]; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of MPO protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of MPO protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of MPO protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MPO protein] Curcumin analog results in decreased activity of MPO protein Curcumin results in decreased activity of MPO protein
|
CTD |
PMID:16804969 PMID:16867261 PMID:17276891 PMID:17351913 PMID:17373747 PMID:17461496 PMID:17973899 PMID:19002562 PMID:20885979 PMID:23291280 PMID:25461551 PMID:32718261 PMID:34272803 PMID:34998855 PMID:36178099 PMID:38141737 More...
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|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
|
|
| G
|
Mrpl1
|
mitochondrial ribosomal protein L1
|
increases expression
|
ISO
|
Curcumin results in increased expression of MRPL1 mRNA
|
CTD |
PMID:17198877 |
|
NCBI chr14:13,604,498...13,663,633
Ensembl chr14:13,604,499...13,663,602
|
|
| G
|
Mrpl47
|
mitochondrial ribosomal protein L47
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 2:117,436,199...117,447,790
Ensembl chr 2:117,428,621...117,447,517
|
|
| G
|
Ms4a1
|
membrane spanning 4-domains A1
|
decreases expression increases expression
|
ISO
|
Curcumin results in decreased expression of MS4A1 mRNA Curcumin results in increased expression of MS4A1 mRNA
|
CTD |
PMID:17198877 PMID:18421014 |
|
NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:217,331,274...217,343,447
|
|
| G
|
Msmo1
|
methylsterol monooxygenase 1
|
affects expression decreases expression
|
ISO EXP
|
Curcumin affects the expression of MSMO1 mRNA Curcumin results in decreased expression of MSMO1 mRNA
|
CTD |
PMID:27208389 |
|
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
|
|
| G
|
Msn
|
moesin
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr X:65,005,546...65,073,512
Ensembl chr X:65,005,458...65,075,129
|
|
| G
|
Msr1
|
macrophage scavenger receptor 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of MSR1 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]
|
CTD |
PMID:23386263 |
|
NCBI chr16:59,421,250...59,507,070
Ensembl chr16:59,421,057...59,507,070
|
|
| G
|
Msra
|
methionine sulfoxide reductase A
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of MSRA protein]
|
CTD |
PMID:38272317 |
|
NCBI chr15:42,514,818...42,853,278
Ensembl chr15:42,527,045...42,853,279
|
|
| G
|
Msrb2
|
methionine sulfoxide reductase B2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of MSRB2 protein]
|
CTD |
PMID:38272317 |
|
NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391
|
|
| G
|
Mst1r
|
macrophage stimulating 1 receptor
|
multiple interactions decreases expression
|
ISO
|
Curcumin inhibits the reaction [RELA protein binds to MST1R promoter]; Curcumin inhibits the reaction [RELA protein results in increased expression of MST1R mRNA] Curcumin results in decreased expression of MST1R mRNA; Curcumin results in decreased expression of MST1R protein
|
CTD |
PMID:18593918 |
|
NCBI chr 8:117,471,928...117,491,059
Ensembl chr 8:117,475,968...117,490,515
|
|
| G
|
Mt-co1
|
mitochondrially encoded cytochrome c oxidase I
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of COX1 mRNA
|
CTD |
PMID:37634662 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853
|
|
| G
|
Mt-co2
|
mitochondrially encoded cytochrome c oxidase II
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of COX2 mRNA 3-methyladenine inhibits the reaction [Curcumin results in decreased expression of COX2 protein]; Curcumin results in increased degradation of and results in decreased expression of COX2 protein
|
CTD |
PMID:37634662 |
|
NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674
|
|
| G
|
Mt-nd1
|
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of ND1 mRNA
|
CTD |
PMID:37634662 |
|
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,729...3,685
|
|
| G
|
Mt1a
|
metallothionein 1A
|
multiple interactions increases expression
|
EXP
|
Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT1A mRNA]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MT1 protein] Curcumin results in increased expression of MT1A mRNA
|
CTD |
PMID:20229497 PMID:31199764 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
|
|
| G
|
Mt2
|
metallothionein 2
|
multiple interactions increases expression
|
EXP
|
Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT2A mRNA] Curcumin results in increased expression of MT2A mRNA
|
CTD |
PMID:20229497 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
decreases phosphorylation multiple interactions decreases expression
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ISO EXP
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Curcumin results in decreased phosphorylation of MTOR protein MIR206 affects the reaction [Curcumin results in decreased phosphorylation of MTOR protein] ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of MTOR protein] 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein]; Curcumin analog inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of and results in increased phosphorylation of MTOR protein]; Curcumin promotes the reaction [Sirolimus results in decreased phosphorylation of MTOR protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of MTOR protein Curcumin analog results in decreased expression of MTOR mRNA; Curcumin results in decreased expression of MTOR mRNA
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CTD |
PMID:20554536 PMID:21450334 PMID:26409325 PMID:27363783 PMID:33582110 PMID:36640941 PMID:38141737 PMID:38764151 More...
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NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
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| G
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Muc5ac
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mucin 5AC, oligomeric mucus/gel-forming
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multiple interactions
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ISO
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Curcumin inhibits the reaction [o,p'-DDT results in increased expression of MUC5AC mRNA]
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CTD |
PMID:34167450 |
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NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
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| G
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Mvd
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mevalonate diphosphate decarboxylase
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decreases expression
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ISO
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Curcumin results in decreased expression of MVD mRNA
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CTD |
PMID:17198877 |
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NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366
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| G
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Mvk
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mevalonate kinase
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affects expression decreases expression
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ISO EXP
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Curcumin affects the expression of MVK mRNA Curcumin results in decreased expression of MVK mRNA
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CTD |
PMID:27208389 |
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NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503
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| G
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Mxd1
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max dimerization protein 1
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increases expression
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ISO
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Curcumin results in increased expression of MXD1 mRNA
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CTD |
PMID:15713895 |
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NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:120,654,731...120,675,129
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| G
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Mxd3
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Max dimerization protein 3
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decreases expression
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ISO
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Curcumin results in decreased expression of MXD3 mRNA
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CTD |
PMID:15713895 PMID:17198877 |
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NCBI chr17:9,306,552...9,310,278
Ensembl chr17:9,302,321...9,310,278
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| G
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Mybpc3
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myosin binding protein C3
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multiple interactions
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EXP
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Curcumin inhibits the reaction [Gentamicins results in increased expression of MYBPC3 mRNA]
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CTD |
PMID:38056816 |
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NCBI chr 3:97,550,974...97,569,216
Ensembl chr 3:97,551,061...97,569,216
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| G
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Myc
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MYC proto-oncogene, bHLH transcription factor
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multiple interactions increases expression decreases expression
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ISO
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[Curcumin co-treated with Doxorubicin] affects the expression of MYC mRNA; Curcumin inhibits the reaction [Paclitaxel results in increased expression of MYC protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of MYC mRNA] [Curcumin co-treated with Gemcitabine] results in decreased expression of MYC protein; Curcumin inhibits the reaction [Cisplatin results in decreased phosphorylation of MYC protein] Curcumin results in increased expression of MYC mRNA Curcumin analog results in decreased expression of MYC protein; Curcumin results in decreased expression of MYC mRNA; Curcumin results in decreased expression of MYC protein
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CTD |
PMID:15713895 PMID:15911101 PMID:16219905 PMID:16243823 PMID:17041101 PMID:17440100 PMID:36178099 More...
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NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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| G
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Myd88
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MYD88, innate immune signal transduction adaptor
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multiple interactions
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ISO EXP
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Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of MYD88 mRNA] Curcumin inhibits the reaction [Cisplatin results in increased expression of MYD88 protein] Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]
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CTD |
PMID:19002562 PMID:23452621 PMID:34719837 PMID:36178099 |
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NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
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| G
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Myh1
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myosin heavy chain 1
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decreases expression
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EXP
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Curcumin results in decreased expression of MYH1 mRNA
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CTD |
PMID:18299980 |
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NCBI chr10:52,384,810...52,408,698
Ensembl chr10:52,384,908...52,409,047
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| G
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Myh6
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myosin heavy chain 6
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decreases expression
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ISO
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Curcumin results in decreased expression of MYH6 mRNA
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CTD |
PMID:27237783 |
|
NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333
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| G
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Myh7
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myosin heavy chain 7
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multiple interactions decreases expression
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EXP
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carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of MYH7 mRNA]; Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]; Curcumin promotes the reaction [KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]]; KN 93 promotes the reaction [Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]]
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CTD |
PMID:25093688 PMID:26612707 |
|
NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194
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| G
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Myl12a
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myosin light chain 12A
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increases expression
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ISO
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Curcumin results in increased expression of MYL12A mRNA
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CTD |
PMID:17999991 |
|
NCBI chr 9:118,338,592...118,346,277
Ensembl chr 9:118,338,604...118,342,634
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| G
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Myl4
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myosin, light chain 4
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decreases expression
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ISO
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Curcumin results in decreased expression of MYL4 mRNA
|
CTD |
PMID:27237783 |
|
NCBI chr10:89,949,733...89,985,308
Ensembl chr10:89,949,404...89,985,308
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| G
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Myl9
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myosin light chain 9
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multiple interactions
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ISO
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Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYL9 protein modified form]
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CTD |
PMID:35817260 |
|
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
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| G
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Mylk
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myosin light chain kinase
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increases expression multiple interactions
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ISO
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Curcumin results in increased expression of MYLK mRNA Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK protein]
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CTD |
PMID:21594647 PMID:35817260 |
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NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
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| G
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Myo18a
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myosin XVIIIa
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increases expression
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ISO
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Curcumin results in increased expression of MYO18A mRNA
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CTD |
PMID:18421014 |
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NCBI chr10:63,152,303...63,253,543
Ensembl chr10:63,152,103...63,253,543
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| G
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Naip6
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NLR family, apoptosis inhibitory protein 6
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decreases expression multiple interactions
|
ISO
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Curcumin analog results in decreased expression of NAIP mRNA; Curcumin results in decreased expression of NAIP mRNA [Curcumin co-treated with Doxorubicin] affects the expression of NAIP mRNA; [Curcumin co-treated with Oxygen deficiency] results in decreased expression of NAIP protein
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CTD |
PMID:15911101 PMID:17671737 PMID:19250217 PMID:23452621 |
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NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:33,241,521...33,276,859
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| G
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Nanog
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Nanog homeobox
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multiple interactions increases expression
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ISO
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2-methoxyestradiol inhibits the reaction [Curcumin results in increased expression of NANOG mRNA] Curcumin results in increased expression of NANOG mRNA; Curcumin results in increased expression of NANOG protein
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CTD |
PMID:25822711 PMID:27237783 |
|
NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061
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| G
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Nanos1
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nanos C2HC-type zinc finger 1
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decreases expression
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ISO
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Curcumin results in decreased expression of NANOS1 mRNA
|
CTD |
PMID:17999991 |
|
NCBI chr 1:269,883,713...269,887,611
Ensembl chr 1:269,883,536...269,895,417
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| G
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Ncam1
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neural cell adhesion molecule 1
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increases expression
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EXP
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Curcumin results in increased expression of NCAM1 protein modified form
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CTD |
PMID:19161989 |
|
NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971
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|
| G
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Ncoa1
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nuclear receptor coactivator 1
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multiple interactions
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ISO
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Curcumin promotes the reaction [VDR protein binds to NCOA1 protein]
|
CTD |
PMID:20153625 |
|
NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
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|
| G
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Nefm
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neurofilament medium chain
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increases expression
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EXP
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Curcumin results in increased expression of NEFM mRNA
|
CTD |
PMID:18299980 |
|
NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163
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|
| G
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Neil1
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nei-like DNA glycosylase 1
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Copper binds to and results in decreased activity of NEIL1 protein]; Curcumin inhibits the reaction [Iron binds to and results in decreased activity of NEIL1 protein]
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CTD |
PMID:20622253 |
|
NCBI chr 8:66,446,106...66,452,844
Ensembl chr 8:66,445,953...66,452,378
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| G
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Nes
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nestin
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multiple interactions increases expression
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EXP
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Curcumin inhibits the reaction [bisphenol A results in decreased expression of NES mRNA]; Curcumin inhibits the reaction [Gentamicins results in increased expression of NES mRNA] Curcumin results in increased expression of NES mRNA
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CTD |
PMID:25963729 PMID:38056816 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
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| G
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Neurod1
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neuronal differentiation 1
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multiple interactions increases expression
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EXP
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Curcumin inhibits the reaction [bisphenol A results in decreased expression of NEUROD1 mRNA] Curcumin results in increased expression of NEUROD1 mRNA
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CTD |
PMID:25963729 |
|
NCBI chr 3:84,766,483...84,770,454
Ensembl chr 3:84,764,725...84,770,810
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| G
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Neurog1
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neurogenin 1
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multiple interactions increases expression
|
EXP
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Curcumin inhibits the reaction [bisphenol A results in decreased expression of NEUROG1 mRNA] Curcumin results in increased expression of NEUROG1 mRNA
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CTD |
PMID:25963729 |
|
NCBI chr17:8,368,096...8,369,615
Ensembl chr17:8,368,096...8,369,615
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| G
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Nfe2l1
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NFE2 like bZIP transcription factor 1
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increases expression
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ISO
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Curcumin results in increased expression of NFE2L1 protein
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CTD |
PMID:23710286 |
|
NCBI chr10:82,296,824...82,309,472
Ensembl chr10:82,292,508...82,309,375
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| G
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Nfe2l2
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NFE2 like bZIP transcription factor 2
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multiple interactions decreases methylation affects localization increases localization increases expression decreases response to substance increases activity
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ISO EXP
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[Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 protein; Curcumin inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of NFE2L2 protein]; Curcumin promotes the reaction [Furazolidone results in increased expression of NFE2L2 protein]; Curcumin promotes the reaction [NFE2L2 protein binds to GSTP1 promoter]; Curcumin promotes the reaction [NFE2L2 protein results in increased expression of GSTP1 mRNA]; Curcumin promotes the reaction [quinocetone results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NFE2L2 protein]; Curcumin results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLM mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLM mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [[Curcumin co-treated with sodium arsenite] promotes the reaction TFEB protein]; NFE2L2 protein affects the reaction [Curcumin analog results in decreased susceptibility to Acrolein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of BCL2 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of SOD2 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of LAMP1 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein]]; NFE2L2 protein affects the reaction [Curcumin results in decreased susceptibility to Acrolein] Curcumin analog results in decreased methylation of NFE2L2 promoter Curcumin affects the localization of NFE2L2 protein; Curcumin analog affects the localization of NFE2L2 protein Curcumin results in increased localization of NFE2L2 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin affects the localization of NFE2L2 protein]; [Curcumin analog co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; [Curcumin co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [decamethrin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Gentamicins results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein modified form]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [maleic acid affects the expression of NFE2L2 protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of NFE2L2 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; Curcumin inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein]; Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]; Curcumin results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein promotes the reaction [Curcumin results in increased activity of RELA protein]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 mRNA]]; pyrazolanthrone inhibits the reaction [Curcumin affects the localization of NFE2L2 protein]; SB 203580 inhibits the reaction [Curcumin affects the localization of NFE2L2 protein] Curcumin analog results in increased expression of NFE2L2 mRNA; Curcumin analog results in increased expression of NFE2L2 protein; Curcumin results in increased expression of NFE2L2 mRNA; Curcumin results in increased expression of NFE2L2 protein [Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 protein; [Curcumin co-treated with Benzo(a)pyrene] affects the localization of NFE2L2 protein; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 protein]; Curcumin promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NFE2L2 protein]; Curcumin results in increased expression of and results in increased localization of NFE2L2 protein; NFE2L2 gene mutant form affects the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of CASP3 protein modified form]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL1B mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL6 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of TNF mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of BCL2 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA] NFE2L2 gene mutant form results in decreased susceptibility to Curcumin Curcumin analog results in increased expression of NFE2L2 protein; Curcumin results in increased expression of NFE2L2 mRNA; Curcumin results in increased expression of NFE2L2 protein; Curcumin results in increased expression of NFE2L2 protein modified form Curcumin results in increased activity of NFE2L2 protein
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CTD |
PMID:17449203 PMID:17535857 PMID:17640564 PMID:18006204 PMID:18321868 PMID:18588981 PMID:19177192 PMID:19183254 PMID:23710286 PMID:23871787 PMID:23954767 PMID:24952339 PMID:25119790 PMID:25169090 PMID:25387343 PMID:25541178 PMID:26361869 PMID:26991801 PMID:27375190 PMID:27837179 PMID:27996348 PMID:29228771 PMID:29571711 PMID:30114225 PMID:30946834 PMID:31187328 PMID:31330227 PMID:31454128 PMID:31521693 PMID:32718261 PMID:33350580 PMID:34272803 PMID:34758851 PMID:35063475 PMID:35243748 PMID:36037877 PMID:36305173 PMID:37741124 PMID:38056816 PMID:38141737 PMID:38272317 More...
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|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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| G
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Nfkb1
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nuclear factor kappa B subunit 1
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multiple interactions decreases activity decreases expression decreases localization
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ISO EXP
|
Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to IL18 promoter]]; Curcumin inhibits the reaction [Oxygen deficiency affects the localization of NFKB1 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased activity of NFKB1 protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Curcumin results in decreased activity of [NFKB1 protein binds to RELA protein]; Dithiothreitol inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]] Curcumin analog results in decreased activity of NFKB1 protein; Curcumin results in decreased activity of NFKB1 protein [Zinc binds to Curcumin] which affects the expression of NFKB1 mRNA; Curcumin inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]]; Curcumin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of NFKB1 protein] Curcumin inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKB1 protein]; Curcumin inhibits the reaction [NFKB1 protein binds to RELA protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of NFKB1 mRNA] Curcumin results in decreased expression of NFKB1 protein Curcumin results in decreased localization of NFKB1 protein
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CTD |
PMID:15489888 PMID:16023083 PMID:16173963 PMID:16219905 PMID:16243823 PMID:16299251 PMID:17041101 PMID:17399992 PMID:17596214 PMID:17640567 PMID:17887948 PMID:18006147 PMID:18555241 PMID:18593936 PMID:18752423 PMID:19225048 PMID:19589337 PMID:21811692 PMID:23452621 PMID:34272803 PMID:38056805 More...
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NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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| G
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Nfkb2
|
nuclear factor kappa B subunit 2
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decreases activity
|
ISO
|
Curcumin results in decreased activity of NFKB2 protein
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CTD |
PMID:16173963 |
|
NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
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|
| G
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Nfkbia
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NFKB inhibitor alpha
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multiple interactions decreases phosphorylation increases expression decreases expression
|
ISO EXP
|
Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of NFKBIA protein modified form]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [NFKBIA protein results in increased degradation of RELA protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [Paclitaxel results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Sodium Fluoride results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA]; NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL2 mRNA]; NFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA] Curcumin inhibits the reaction [Fluorouracil results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of NFKBIA protein] Curcumin results in decreased phosphorylation of NFKBIA protein Curcumin results in increased expression of NFKBIA protein CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Freund's Adjuvant results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Fructose results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]] Curcumin results in decreased expression of NFKBIA protein
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CTD |
PMID:12216086 PMID:15489888 PMID:15793857 PMID:16023083 PMID:16219905 PMID:16243823 PMID:16819191 PMID:16934299 PMID:17289836 PMID:17291458 PMID:17666914 PMID:17885582 PMID:17927689 PMID:17965732 PMID:17999991 PMID:18413660 PMID:23452621 PMID:25540590 PMID:26713546 PMID:27194111 PMID:29793316 PMID:30431687 PMID:31521693 PMID:34272803 PMID:35549587 PMID:38056805 More...
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|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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| G
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Nfkbib
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NFKB inhibitor beta
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multiple interactions
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EXP
|
Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein]
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CTD |
PMID:16934299 |
|
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
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| G
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Nfya
|
nuclear transcription factor Y subunit alpha
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decreases expression
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ISO
|
Curcumin results in decreased expression of NFYA mRNA
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CTD |
PMID:15713895 |
|
NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504
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|
| G
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Ngfr
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nerve growth factor receptor
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decreases expression
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ISO
|
Curcumin results in decreased expression of NGFR mRNA
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CTD |
PMID:33539684 |
|
NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305
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|
| G
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Nhlrc2
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NHL repeat containing 2
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decreases expression
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ISO
|
Curcumin results in decreased expression of NHLRC2 mRNA
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CTD |
PMID:17999991 |
|
NCBI chr 1:265,594,915...265,655,647
Ensembl chr 1:265,594,915...265,676,143
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| G
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Nkx2-5
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NK2 homeobox 5
|
decreases expression
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ISO
|
Curcumin results in decreased expression of NKX2-5 mRNA
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CTD |
PMID:27237783 |
|
NCBI chr10:16,844,888...16,851,458
Ensembl chr10:16,848,582...16,851,452
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| G
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Nkx3-1
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NK3 homeobox 1
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decreases expression
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ISO
|
Curcumin results in decreased expression of NKX3-1 mRNA; Curcumin results in decreased expression of NKX3-1 protein
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CTD |
PMID:17303007 PMID:18719366 |
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NCBI chr15:50,883,661...50,886,253
Ensembl chr15:50,883,597...50,886,251
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| G
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Nlrp12
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NLR family, pyrin domain containing 12
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multiple interactions
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ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NLRP12 mRNA]
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CTD |
PMID:23452621 |
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NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341
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| G
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Nlrp3
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NLR family, pyrin domain containing 3
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multiple interactions
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ISO EXP
|
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 mRNA]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of NLRP3 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of NLRP3 protein]; Curcumin inhibits the reaction [Atrazine results in increased expression of NLRP3 mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of NLRP3 protein] Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of NLRP3 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of NLRP3 mRNA]
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CTD |
PMID:34998855 PMID:35063475 PMID:38301994 PMID:38369055 |
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NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
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| G
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Nme1
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NME/NM23 nucleoside diphosphate kinase 1
|
increases expression
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ISO
|
Curcumin results in increased expression of NME1 mRNA
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CTD |
PMID:17198877 |
|
NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310
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|
| G
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Nmt2
|
N-myristoyltransferase 2
|
multiple interactions
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ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA]
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CTD |
PMID:18200517 |
|
NCBI chr17:79,826,999...79,874,088
Ensembl chr17:79,826,999...79,870,259
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| G
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Nod1
|
nucleotide-binding oligomerization domain containing 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA]
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CTD |
PMID:23452621 |
|
NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:85,391,151...85,441,674
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| G
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Nod2
|
nucleotide-binding oligomerization domain containing 2
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine promotes the reaction [NOD2 protein binds to NOD2 protein]]; Curcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]]
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CTD |
PMID:18413660 |
|
NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846
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|
| G
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Nono
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non-POU domain containing, octamer-binding
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multiple interactions
|
ISO
|
Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of NONO mRNA]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of NONO protein]
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CTD |
PMID:38272317 |
|
NCBI chr X:70,594,116...70,611,976
Ensembl chr X:70,593,888...70,611,979
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| G
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Nos1
|
nitric oxide synthase 1
|
multiple interactions
|
EXP ISO
|
Curcumin promotes the reaction [Sildenafil Citrate results in increased expression of NOS1 mRNA] Curcumin inhibits the reaction [Cadmium Chloride results in decreased expression of NOS1 protein]
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CTD |
PMID:17627722 PMID:24662163 |
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NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837
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|
| G
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Nos2
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nitric oxide synthase 2
|
multiple interactions decreases activity affects expression affects activity
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ISO EXP
|
Curcumin inhibits the reaction [Paraquat results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [quinocetone results in increased activity of NOS2 protein]; Curcumin inhibits the reaction [quinocetone results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]] Curcumin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Chloranil results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]] Curcumin results in decreased activity of NOS2 protein [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; Curcumin analog inhibits the reaction [Rotenone results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NOS2 protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Sodium Selenite results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Sodium Selenite results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of NOS2 protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of NOS2 protein]] Curcumin affects the expression of NOS2 mRNA Curcumin affects the activity of NOS2 protein
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CTD |
PMID:7530002 PMID:12628514 PMID:16934299 PMID:17373747 PMID:17434272 PMID:17461496 PMID:17640567 PMID:17827730 PMID:18368483 PMID:18481332 PMID:18752423 PMID:18838107 PMID:19148301 PMID:19188055 PMID:19481068 PMID:19526292 PMID:20712904 PMID:22982865 PMID:23500011 PMID:25123790 PMID:25387343 PMID:25541178 PMID:27375190 PMID:27535828 PMID:29315967 PMID:32718261 PMID:33350580 PMID:38056816 More...
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NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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| G
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Nos3
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nitric oxide synthase 3
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOS3 protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOS3 protein]
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CTD |
PMID:18660423 PMID:23452621 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
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| G
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Notch1
|
notch receptor 1
|
decreases expression multiple interactions
|
ISO
|
Curcumin results in decreased expression of NOTCH1 mRNA; Curcumin results in decreased expression of NOTCH1 protein [Curcumin co-treated with Isoflavones] results in decreased expression of NOTCH1 protein
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CTD |
PMID:17927689 PMID:18640131 |
|
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
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|
| G
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Nox4
|
NADPH oxidase 4
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multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Cyclosporine results in increased expression of NOX4 protein]
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CTD |
PMID:32569592 |
|
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
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|
| G
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Npc1l1
|
NPC1 like intracellular cholesterol transporter 1
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [bisphenol A results in increased expression of NPC1L1 protein]
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CTD |
PMID:37701206 |
|
NCBI chr14:85,285,387...85,305,050
Ensembl chr14:85,285,390...85,305,050
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|
| G
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Npc2
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NPC intracellular cholesterol transporter 2
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of NPC2 mRNA
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CTD |
PMID:17198877 |
|
NCBI chr 6:110,128,325...110,149,245
Ensembl chr 6:110,128,325...110,150,004
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|
| G
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Nploc4
|
NPL4 homolog, ubiquitin recognition factor
|
increases expression
|
ISO
|
Curcumin results in increased expression of NPLOC4 mRNA; Curcumin results in increased expression of NPLOC4 protein
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CTD |
PMID:38229314 |
|
NCBI chr10:106,152,756...106,208,306
Ensembl chr10:106,153,173...106,208,264
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|
| G
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Nppa
|
natriuretic peptide A
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multiple interactions decreases expression
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EXP
|
carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of NPPA mRNA]
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CTD |
PMID:26612707 |
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NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
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|
| G
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Nqo1
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NAD(P)H quinone dehydrogenase 1
|
increases expression increases activity multiple interactions
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EXP ISO
|
Curcumin results in increased expression of NQO1 mRNA; Curcumin results in increased expression of NQO1 protein Curcumin results in increased activity of NQO1 protein Curcumin analog results in increased expression of NQO1 mRNA; Curcumin analog results in increased expression of NQO1 protein; Curcumin results in increased expression of NQO1 mRNA; Curcumin results in increased expression of NQO1 protein Curcumin analog inhibits the reaction [Rotenone results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NQO1 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of NQO1 protein] [Curcumin co-treated with Chloranil] results in increased expression of NQO1 protein; Curcumin affects the expression of and results in increased activity of NQO1 protein; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NQO1 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein] Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]
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CTD |
PMID:12628514 PMID:17198877 PMID:17535857 PMID:18299980 PMID:18321868 PMID:19188863 PMID:21464371 PMID:23710286 PMID:23871787 PMID:23954767 PMID:25123790 PMID:25169090 PMID:26473469 PMID:26623679 PMID:26991801 PMID:27535828 PMID:29228771 PMID:29571711 PMID:31330227 PMID:31521693 PMID:33350580 PMID:34272803 PMID:35063475 PMID:36037877 PMID:36305173 PMID:38141737 PMID:38272317 More...
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|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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| G
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Nr1h3
|
nuclear receptor subfamily 1, group H, member 3
|
increases expression multiple interactions
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ISO
|
Curcumin results in increased expression of NR1H3 mRNA Curcumin inhibits the reaction [bisphenol A results in increased expression of NR1H3 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of NR1H3 protein] [Curcumin cotreated with oxidized LDL] increases expression of Nr1h3 protein in macrophages
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CTD RGD |
PMID:16713233 PMID:37701206 PMID:25064633 |
RGD:401850557 |
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532
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|
| G
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Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
increases activity affects expression
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ISO
|
Curcumin results in increased activity of NR1I2 protein Curcumin affects the expression of NR1I2 mRNA
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CTD |
PMID:17210444 PMID:29933105 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
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| G
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Nr3c1
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nuclear receptor subfamily 3, group C, member 1
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increases expression multiple interactions
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EXP ISO
|
Curcumin results in increased expression of NR3C1 mRNA Curcumin inhibits the reaction [Dexamethasone results in increased phosphorylation of NR3C1 protein]
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CTD |
PMID:17022948 PMID:18483179 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
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| G
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Nr4a2
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nuclear receptor subfamily 4, group A, member 2
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decreases expression
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ISO
|
Curcumin results in decreased expression of NR4A2 mRNA
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CTD |
PMID:17999991 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
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| G
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Nrip1
|
nuclear receptor interacting protein 1
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decreases expression multiple interactions
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ISO
|
Curcumin results in decreased expression of NRIP1 mRNA alternative form NRIP1 mRNA alternative form inhibits the reaction [Curcumin results in increased expression of MIR532 mRNA]
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CTD |
PMID:37471645 |
|
NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353
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|
| G
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Ntn1
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netrin 1
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multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Cadmium Chloride results in increased export of NTN1 protein]
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CTD |
PMID:29421648 |
|
NCBI chr10:53,398,852...53,597,595
Ensembl chr10:53,398,852...53,584,060
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|
| G
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Ntrk2
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neurotrophic receptor tyrosine kinase 2
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of NTRK2 protein]
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CTD |
PMID:29723552 |
|
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
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|
| G
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Nup98
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nucleoporin 98 and 96 precursor
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increases expression
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ISO
|
Curcumin results in increased expression of NUP98 mRNA
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CTD |
PMID:17198877 |
|
NCBI chr 1:165,906,405...166,003,366
Ensembl chr 1:165,906,405...166,003,366
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|
| G
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Oat
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ornithine aminotransferase
|
affects expression
|
EXP
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Curcumin affects the expression of OAT mRNA
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CTD |
PMID:18539377 |
|
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
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|
| G
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Ocln
|
occludin
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multiple interactions
|
ISO
|
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]
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CTD |
PMID:35817260 |
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NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
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|
| G
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Odc1
|
ornithine decarboxylase 1
|
increases expression multiple interactions
|
ISO
|
Curcumin results in increased expression of ODC1 mRNA Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]
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CTD |
PMID:12628514 PMID:17198877 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
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|
| G
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Ogg1
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8-oxoguanine DNA glycosylase
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 mRNA]; Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 protein]
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CTD |
PMID:21332098 |
|
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
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|
| G
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Olr1
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oxidized low density lipoprotein receptor 1
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multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]
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CTD |
PMID:23386263 |
|
NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598
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|
| G
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Opa1
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OPA1, mitochondrial dynamin like GTPase
|
multiple interactions
|
EXP
|
Curcumin inhibits the reaction [Cisplatin results in decreased expression of OPA1 protein]
|
CTD |
PMID:28698153 |
|
NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
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|
| G
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Os9
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OS9, endoplasmic reticulum lectin
|
increases expression
|
ISO
|
Curcumin results in increased expression of OS9 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:64,802,103...64,829,070
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|
| G
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Osmr
|
oncostatin M receptor
|
multiple interactions
|
ISO
|
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA]
|
CTD |
PMID:18200517 |
|
NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561
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|
| G
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Otub1
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OTU deubiquitinase, ubiquitin aldehyde binding 1
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of OTUB1 mRNA
|
CTD |
PMID:38229314 |
|
NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679
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|
| G
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Otud7b
|
OTU deubiquitinase 7B
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of OTUD7B mRNA
|
CTD |
PMID:18421014 |
|
NCBI chr 2:186,350,811...186,411,461
Ensembl chr 2:186,350,798...186,409,440
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|
| G
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Pah
|
phenylalanine hydroxylase
|
decreases expression
|
ISO
|
Curcumin results in decreased expression of PAH mRNA
|
CTD |
PMID:19555370 |
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NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627
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| G
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Pak2
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p21 (RAC1) activated kinase 2
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decreases cleavage
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ISO
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Curcumin results in decreased cleavage of PAK2 protein
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CTD |
PMID:15095415 |
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NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803
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| G
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Parp1
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poly (ADP-ribose) polymerase 1
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multiple interactions increases expression decreases cleavage decreases expression increases cleavage increases degradation
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ISO EXP
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[Curcumin co-treated with Bortezomib] results in increased cleavage of PARP1 protein; [Curcumin co-treated with Thalidomide] results in increased cleavage of PARP1 protein; arsenic trioxide promotes the reaction [Curcumin results in increased expression of PARP1 protein modified form]; Curcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of PARP1 protein]; Curcumin inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; Curcumin promotes the reaction [arsenic trioxide results in increased expression of PARP1 protein modified form]; Curcumin promotes the reaction [arsenite results in increased expression of PARP1 protein]; Curcumin results in increased cleavage of and results in increased activity of PARP1 protein Curcumin results in decreased cleavage of PARP1 protein Curcumin analog results in decreased expression of PARP1 mRNA Curcumin results in increased cleavage of PARP1 protein carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased cleavage of PARP1 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein] [Doxorubicin co-treated with Curcumin] results in increased cleavage of PARP1 protein; Curcumin inhibits the reaction [Cisplatin results in increased expression of PARP1 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] Curcumin results in increased degradation of PARP1
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CTD |
PMID:11035063 PMID:14555224 PMID:14724571 PMID:15569404 PMID:16023083 PMID:16173963 PMID:17671742 PMID:18006147 PMID:18392098 PMID:18593936 PMID:19235267 PMID:19372569 PMID:19401701 PMID:21332098 PMID:21594647 PMID:21595920 PMID:23710286 PMID:24664296 PMID:25541178 PMID:26409325 PMID:26612707 PMID:27430728 PMID:36178099 More...
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NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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| G
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Pax6
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paired box 6
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multiple interactions increases expression
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EXP
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Curcumin inhibits the reaction [bisphenol A results in decreased expression of PAX6 mRNA] Curcumin results in increased expression of PAX6 mRNA
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CTD |
PMID:25963729 |
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NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763
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| G
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Pck1
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phosphoenolpyruvate carboxykinase 1
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decreases expression affects expression
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ISO
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Curcumin results in decreased expression of PCK1 mRNA Curcumin affects the expression of PCK1 mRNA
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CTD |
PMID:17198877 PMID:27208389 |
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NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
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| G
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Pcna
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proliferating cell nuclear antigen
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decreases expression multiple interactions increases expression
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ISO EXP
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Curcumin results in decreased expression of PCNA protein [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of PCNA protein]; [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of PCNA protein [Dihydrotestosterone co-treated with Curcumin co-treated with Quercetin] results in increased expression of PCNA protein; Curcumin inhibits the reaction [bisphenol A results in increased expression of PCNA protein] Curcumin results in increased expression of PCNA mRNA
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CTD |
PMID:16101141 PMID:18226269 PMID:23222814 PMID:24831732 PMID:26612707 PMID:27132804 More...
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NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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| G
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Pcsk9
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proprotein convertase subtilisin/kexin type 9
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affects expression
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ISO
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Curcumin affects the expression of PCSK9 mRNA
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CTD |
PMID:27208389 |
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NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507
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| G
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Pdgfb
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platelet derived growth factor subunit B
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multiple interactions
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EXP
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Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFB protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]
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CTD |
PMID:18006644 PMID:18784349 |
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NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
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| G
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Pdgfrb
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platelet derived growth factor receptor beta
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increases expression decreases phosphorylation multiple interactions decreases expression
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ISO EXP
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Curcumin results in increased expression of PDGFRB mRNA Curcumin results in decreased phosphorylation of PDGFRB protein Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA] Curcumin results in decreased expression of PDGFRB mRNA; Curcumin results in decreased expression of PDGFRB protein
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CTD |
PMID:17372590 PMID:18006644 PMID:18332871 PMID:21594647 |
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NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
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| G
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Pdia3
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protein disulfide isomerase family A, member 3
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increases expression
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ISO
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Curcumin results in increased expression of PDIA3 mRNA
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CTD |
PMID:29723631 |
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NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
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| G
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Pdk1
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pyruvate dehydrogenase kinase 1
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multiple interactions increases phosphorylation
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ISO
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Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein]
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CTD |
PMID:17171638 |
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NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
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| G
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Pdpk1
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3-phosphoinositide dependent protein kinase-1
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decreases phosphorylation
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ISO
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Curcumin results in decreased phosphorylation of PDPK1 protein
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CTD |
PMID:34634291 |
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NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181
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| G
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Pdpn
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podoplanin
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA]
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CTD |
PMID:18200517 |
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NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637
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| G
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Pecam1
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platelet and endothelial cell adhesion molecule 1
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affects expression increases expression multiple interactions decreases expression
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ISO EXP
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Curcumin affects the expression of PECAM1 protein Curcumin results in increased expression of PECAM1 protein Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PECAM1 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PECAM1 protein] Gemcitabine promotes the reaction [Curcumin results in decreased expression of PECAM1 protein] Curcumin inhibits the reaction [Particulate Matter results in increased expression of PECAM1 protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of PECAM1 protein]
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CTD |
PMID:17440100 PMID:17960570 PMID:23845850 PMID:29244817 |
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NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839
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| G
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Per2
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period circadian regulator 2
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increases expression
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ISO
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Curcumin results in increased expression of PER2 mRNA
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CTD |
PMID:17198877 |
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NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
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| G
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Pfkfb4
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6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
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decreases expression
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ISO
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Curcumin results in decreased expression of PFKFB4 mRNA
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CTD |
PMID:17198877 |
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NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:118,522,365...118,565,468
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| G
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Pgd
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phosphogluconate dehydrogenase
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increases expression
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EXP
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Curcumin results in increased expression of PGD mRNA
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CTD |
PMID:18299980 |
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NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
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| G
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Pgf
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placental growth factor
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multiple interactions
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EXP
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Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PGF mRNA]
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CTD |
PMID:23845850 |
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NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747
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| G
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Pgs1
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phosphatidylglycerophosphate synthase 1
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA]
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CTD |
PMID:18200517 |
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NCBI chr10:103,713,306...103,748,924
Ensembl chr10:103,713,316...103,749,233
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| G
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Phb1
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prohibitin 1
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decreases expression
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ISO
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Curcumin results in decreased expression of PHB1 protein
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CTD |
PMID:19137819 |
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NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233
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| G
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Phyh
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phytanoyl-CoA 2-hydroxylase
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decreases expression
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EXP
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Curcumin results in decreased expression of PHYH mRNA
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CTD |
PMID:18539377 |
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NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
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| G
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Pik3c2a
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phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
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decreases expression
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ISO
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Curcumin analog results in decreased expression of PIK3C2A mRNA
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CTD |
PMID:26409325 |
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NCBI chr 1:180,012,248...180,117,786
Ensembl chr 1:180,012,248...180,117,773
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| G
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Pik3ca
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phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
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decreases expression
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ISO
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Curcumin analog results in decreased expression of PIK3CA mRNA
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CTD |
PMID:26409325 |
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NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411
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| G
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Pink1
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PTEN induced kinase 1
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multiple interactions
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EXP
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Curcumin inhibits the reaction [Cisplatin results in increased expression of PINK1 protein]
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CTD |
PMID:28698153 |
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NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
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| G
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Pir
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pirin
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increases expression
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EXP
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Curcumin results in increased expression of PIR mRNA
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CTD |
PMID:18299980 |
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NCBI chr X:33,740,428...33,851,049
Ensembl chr X:33,740,429...33,851,049
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| G
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Pirb
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paired Ig-like receptor B
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multiple interactions
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ISO
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Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA]
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CTD |
PMID:18200517 |
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NCBI chr 1:74,414,556...74,433,015
Ensembl chr 1:74,331,291...74,422,116
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| G
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Pkm
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pyruvate kinase M1/2
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multiple interactions
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ISO
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ATF4 inhibits the reaction [Curcumin results in decreased expression of PKM protein]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of PKM protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of PKM protein]
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CTD |
PMID:36640941 |
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NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
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| G
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Pla2g2a
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phospholipase A2 group IIA
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multiple interactions
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ISO
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Curcumin inhibits the reaction |