Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:clopidogrel
go back to main search page
Accession:CHEBI:37941 term browser browse the term
Definition:A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group, the methylene hydrogen of which is replaced by a methoxycarbonyl group (the S enantiomer). A P2Y12 receptor antagonist, it is used to inhibit blood clots and prevent heart attacks.
Synonyms:exact_synonym: methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
 related_synonym: Formula=C16H16ClNO2S;   InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1;   InChIKey=GKTWGGQPFAXNFI-HNNXBMFYSA-N;   SMILES=COC(=O)[C@@H](N1CCc2sccc2C1)c1ccccc1Cl;   clopidogrelum
 xref: Beilstein:8151914;   CAS:113665-84-2;   DrugBank:DB00758;   Drug_Central:708;   LINCS:LSM-5415
 xref_mesh: MESH:C055162
 xref: PMID:10983738;   PMID:11095576;   PMID:11701941;   PMID:16802846;   PMID:18520712;   PMID:18708826;   PMID:19573725;   Patent:EP281459;   Patent:EP99802;   Patent:US4529596;   Patent:US4847265;   Wikipedia:Clopidogrel



show annotations for term's descendants           Sort by:
clopidogrel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
decreases activity
affects response to substance
increases secretion
decreases expression
decreases uptake
ISO ABCB1 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel]
clopidogrel results in decreased activity of ABCB1 protein
ABCB1 gene affects the susceptibility to clopidogrel; ABCB1 gene polymorphism affects the susceptibility to clopidogrel; ABCB1 gene SNP affects the susceptibility to clopidogrel
ABCB1 protein results in increased secretion of clopidogrel
clopidogrel results in decreased expression of ABCB1 mRNA; clopidogrel results in decreased expression of ABCB1 protein
ABCB1 protein results in decreased uptake of clopidogrel
[Aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel
CTD PMID:17112805 PMID:19106083 PMID:19934793 PMID:20180610 PMID:21900887 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5AP mRNA] CTD PMID:19172522 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
JBrowse link
G Arhgap31 Rho GTPase activating protein 31 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of ARHGAP31 mRNA] CTD PMID:19172522 NCBI chr16:38,418,705...38,533,397
Ensembl chr16:38,418,702...38,533,636
JBrowse link
G Bdnf brain derived neurotrophic factor decreases secretion ISO clopidogrel results in decreased secretion of BDNF protein CTD PMID:21803431 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G C4b complement C4B (Chido blood group) multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of C4B mRNA] CTD PMID:19172522 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
JBrowse link
G Cabin1 calcineurin binding protein 1 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CABIN1 mRNA] CTD PMID:19172522 NCBI chr10:75,481,944...75,600,194
Ensembl chr10:75,481,946...75,600,175
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CAMKK2 mRNA] CTD PMID:19172522 NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression EXP clopidogrel results in increased expression of CCL11 mRNA CTD PMID:19155974 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO clopidogrel results in increased expression of CCL4 mRNA CTD PMID:16856976 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO clopidogrel results in increased expression of CCL5 mRNA CTD PMID:16856976 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cd40lg CD40 ligand multiple interactions
decreases expression
ISO
EXP
clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]
Clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]; Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CD40LG protein]
clopidogrel results in decreased expression of CD40LG protein
CTD PMID:11297035 PMID:17043144 PMID:19155974 PMID:30537341 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd86 CD86 antigen multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 mRNA] CTD PMID:19172522 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Clcn7 chloride channel, voltage-sensitive 7 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CLCN7 mRNA] CTD PMID:19172522 NCBI chr17:25,352,353...25,381,077
Ensembl chr17:25,352,365...25,381,078
JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2RB mRNA] CTD PMID:19172522 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Clopidogrel results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases oxidation
ISO CYP1A2 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite; furafylline inhibits the reaction [CYP1A2 protein results in increased oxidation of clopidogrel] CTD PMID:19170597 PMID:19812348 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Clopidogrel results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases oxidation
multiple interactions
increases expression
ISO CYP2B6 protein results in increased oxidation of clopidogrel
[Clopidogrel co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA
Clopidogrel results in increased expression of CYP2B6 mRNA
CTD PMID:19812348 PMID:31312845 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 multiple interactions ISO CYP2C8 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite CTD PMID:19170597 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions
affects response to substance
affects abundance
decreases metabolic processing
decreases response to substance
increases response to substance
increases metabolic processing
increases oxidation
ISO ABCB1 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel]; CYP2C19 gene affects the reaction [clopidogrel affects the phosphorylation of VASP protein]; CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene polymorphism results in decreased metabolism of and results in decreased activity of clopidogrel; CYP2C19 gene SNP promotes the reaction [CYP2C19 gene SNP affects the susceptibility to clopidogrel]; CYP2C19 protein results in increased metabolism of and results in increased activity of clopidogrel; CYP2C19 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite; CYP2C9 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel]; N-3-benzylnirvanol inhibits the reaction [CYP2C19 protein results in increased oxidation of clopidogrel]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased oxidation of clopidogrel]; P2RY12 gene SNP affects the reaction [CYP2C19 gene SNP affects the susceptibility to clopidogrel]
CYP2C19 gene affects the susceptibility to clopidogrel; CYP2C19 gene polymorphism affects the susceptibility to clopidogrel; CYP2C19 gene SNP affects the susceptibility to clopidogrel
CYP2C19 gene polymorphism affects the abundance of clopidogrel metabolite
CYP2C19 gene polymorphism results in decreased metabolism of clopidogrel; CYP2C19 gene SNP results in decreased metabolism of clopidogrel
CYP2C19 gene polymorphism results in decreased susceptibility to clopidogrel; CYP2C19 gene SNP results in decreased susceptibility to clopidogrel
CYP2C19 gene polymorphism results in increased susceptibility to clopidogrel; CYP2C19 gene SNP results in increased susceptibility to clopidogrel
CYP2C19 protein results in increased metabolism of clopidogrel
CTD PMID:16772608 PMID:17697139 PMID:17900275 PMID:18532997 PMID:18577829 More... NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
affects response to substance
decreases metabolic processing
ISO CYP2C9 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel]; CYP2C9 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite
CYP2C9 gene SNP affects the susceptibility to clopidogrel
CYP2C9 gene SNP results in decreased metabolism of clopidogrel
CTD PMID:17900275 PMID:19170597 PMID:19926050 PMID:19934793 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO CYP2D6 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite CTD PMID:19170597 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 affects response to substance
multiple interactions
ISO CYP3A5 gene polymorphism affects the susceptibility to Clopidogrel
CYP3A5 protein results in increased oxidation of and results in increased cleavage of Clopidogrel metabolite
CTD PMID:16754899 PMID:19170597 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of DUSP1 mRNA] CTD PMID:19172522 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of EIF1A mRNA] CTD PMID:19172522 NCBI chr18:46,730,771...46,743,292
Ensembl chr18:46,730,768...46,749,523
JBrowse link
G F2 coagulation factor II multiple interactions EXP clopidogrel inhibits the reaction [F2 protein results in increased expression of SELP protein] CTD PMID:17043144 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2r coagulation factor II thrombin receptor affects response to substance ISO F2R gene SNP affects the susceptibility to clopidogrel CTD PMID:16194864 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G F3 coagulation factor III multiple interactions EXP Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] CTD PMID:30537341 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Clopidogrel results in decreased expression of G6PC1 mRNA CTD PMID:31312845 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP clopidogrel results in decreased expression of ICAM1 mRNA; clopidogrel results in decreased expression of ICAM1 protein CTD PMID:19155974 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Iglv1 immunoglobulin lambda variable 1 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IGLV1 mRNA] CTD PMID:19172522 NCBI chr16:18,903,767...18,904,210
Ensembl chr16:18,903,767...18,904,250
JBrowse link
G Il10ra interleukin 10 receptor, alpha multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IL10RA mRNA] CTD PMID:19172522 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
JBrowse link
G Il13 interleukin 13 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 mRNA] CTD PMID:19172522 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:30537341 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 increases expression EXP clopidogrel results in increased expression of IL4 mRNA CTD PMID:19155974 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 multiple interactions
increases response to substance
decreases expression
ISO
EXP
clopidogrel promotes the reaction [Silicon Dioxide analog results in increased expression of IL6 protein]
clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
IL6 protein results in increased susceptibility to clopidogrel
clopidogrel results in decreased expression of IL6 mRNA
CTD PMID:17537833 PMID:19155974 PMID:24793913 PMID:24849676 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Itga2 integrin alpha 2 multiple interactions ISO ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate]; ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Epinephrine]; ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel] CTD PMID:15205592 PMID:16214444 NCBI chr13:114,969,617...115,068,588
Ensembl chr13:114,969,617...115,068,636
JBrowse link
G Itgb3 integrin beta 3 decreases response to substance
affects response to substance
ISO ITGB3 gene SNP results in decreased susceptibility to clopidogrel
ITGB3 gene SNP affects the susceptibility to clopidogrel
CTD PMID:15166949 PMID:19530321 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of LTB4R1 mRNA] CTD PMID:19172522 NCBI chr14:56,002,154...56,005,951
Ensembl chr14:56,003,419...56,005,951
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 mRNA] CTD PMID:19172522 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of MCCC2 mRNA] CTD PMID:19172522 NCBI chr13:100,085,040...100,152,147
Ensembl chr13:100,085,038...100,152,147
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO Clopidogrel promotes the reaction [MED1 protein binds to NR1I3 protein alternative form] CTD PMID:31312845 NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119
JBrowse link
G Mir155 microRNA 155 increases expression ISO Clopidogrel results in increased expression of MIR155 mRNA CTD PMID:33208005 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mir17 microRNA 17 decreases expression ISO Clopidogrel results in decreased expression of MIR17 mRNA CTD PMID:33208005 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186
JBrowse link
G Mir363 microRNA 363 increases expression ISO Clopidogrel results in increased expression of MIR363 mRNA CTD PMID:33208005 NCBI chr  X:51,830,570...51,830,644
Ensembl chr  X:51,830,570...51,830,644
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO clopidogrel results in decreased activity of MMP9 protein CTD PMID:20195827 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Clopidogrel inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of MPO protein]; Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:20133375 PMID:30537341 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization
multiple interactions
ISO Clopidogrel affects the localization of NR1I3 protein mutant form
[Clopidogrel co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; Clopidogrel binds to and results in increased activity of NR1I3 protein alternative form; Clopidogrel inhibits the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased activity of NR1I3 protein]; Clopidogrel promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]
CTD PMID:31312845 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Ocln occludin decreases expression
multiple interactions
ISO clopidogrel results in decreased expression of OCLN protein
SB 203580 inhibits the reaction [clopidogrel results in decreased expression of OCLN protein]
CTD PMID:23220562 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 multiple interactions
affects response to substance
increases response to substance
ISO
EXP
clopidogrel binds to and results in decreased activity of P2RY12 protein; P2RY12 gene SNP affects the reaction [CYP2C19 gene SNP affects the susceptibility to clopidogrel]
P2RY12 gene affects the susceptibility to clopidogrel; P2RY12 gene SNP affects the susceptibility to clopidogrel; P2RY12 protein affects the susceptibility to clopidogrel
P2RY12 protein results in increased susceptibility to clopidogrel
CTD PMID:11413167 PMID:15933261 PMID:18404433 PMID:18485500 PMID:18577829 More... NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic increases expression ISO Clopidogrel results in increased expression of PCK1 mRNA CTD PMID:31312845 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide decreases expression EXP clopidogrel results in decreased expression of PDGFB mRNA; clopidogrel results in decreased expression of PDGFB protein CTD PMID:19155974 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pon1 paraoxonase 1 affects response to substance
multiple interactions
ISO PON1 gene polymorphism affects the susceptibility to clopidogrel
PON1 protein results in increased metabolism of and results in increased activity of clopidogrel
CTD PMID:21170047 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Prkcb protein kinase C, beta multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of PRKCB mRNA] CTD PMID:19172522 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of RAN mRNA] CTD PMID:19172522 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of S100A11 mRNA] CTD PMID:19172522 NCBI chr 3:93,427,803...93,433,595
Ensembl chr 3:93,427,795...93,433,594
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 decreases expression ISO Clopidogrel results in decreased expression of SCD mRNA CTD PMID:31312845 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
JBrowse link
G Sele selectin, endothelial cell decreases expression EXP clopidogrel results in decreased expression of SELE mRNA; clopidogrel results in decreased expression of SELE protein CTD PMID:19155974 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Selp selectin, platelet multiple interactions
decreases expression
EXP Clopidogrel inhibits the reaction [F2 protein results in increased expression of SELP protein]; Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of SELP protein]
clopidogrel results in decreased expression of SELP mRNA; clopidogrel results in decreased expression of SELP protein
CTD PMID:17043144 PMID:19155974 PMID:30537341 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Slc3a1 solute carrier family 3, member 1 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of SLC3A1 mRNA] CTD PMID:19172522 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of STAT2 mRNA] CTD PMID:19172522 NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718
JBrowse link
G Sucla2 succinate-Coenzyme A ligase, ADP-forming, beta subunit multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of SUCLA2 mRNA] CTD PMID:19172522 NCBI chr14:73,790,226...73,833,584
Ensembl chr14:73,762,759...73,833,582
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of TGFB1 mRNA]
clopidogrel results in increased expression of TGFB1 mRNA
CTD PMID:19155974 PMID:19172522 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO clopidogrel results in increased expression of THBS1; clopidogrel results in increased expression of THBS1 mRNA; clopidogrel results in increased expression of THBS1 protein CTD PMID:9447704 PMID:11875746 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
G Thrsp thyroid hormone responsive increases expression ISO Clopidogrel results in increased expression of THRSP mRNA CTD PMID:31312845 NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
JBrowse link
G Tjp1 tight junction protein 1 decreases expression
multiple interactions
ISO clopidogrel results in decreased expression of TJP1 protein
SB 203580 inhibits the reaction [clopidogrel results in decreased expression of TJP1 protein]
CTD PMID:23220562 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tmem69 transmembrane protein 69 multiple interactions EXP clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of TMEM69 mRNA] CTD PMID:19172522 NCBI chr 4:116,408,725...116,414,262
Ensembl chr 4:116,409,102...116,413,132
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP clopidogrel results in increased expression of TNF mRNA
Clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:19155974 PMID:30537341 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO clopidogrel results in increased expression of TP53 mRNA; clopidogrel results in increased expression of TP53 protein CTD PMID:9447704 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions ISO CYP2C19 gene affects the reaction [clopidogrel affects the phosphorylation of VASP protein] CTD PMID:16772608 NCBI chr 7:18,990,854...19,005,779
Ensembl chr 7:18,990,854...19,005,742
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        fuel 11462
          methanol 3985
            methyl ester 3920
              clopidogrel 70
                clopidogrel sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            organic molecule 21647
                              organic cyclic compound 21252
                                carbocyclic compound 19682
                                  benzenoid aromatic compound 18819
                                    benzenes 18620
                                      chlorobenzenes 15422
                                        monochlorobenzenes 12065
                                          ticlopidine 85
                                            clopidogrel 70
                                              clopidogrel sulfate 0
paths to the root