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Accession:CHEBI:37924 term browser browse the term
Definition:A heavily substituted carbohydrazide that is an antiretroviral drug of the protease inhibitor (PI) class used to treat infection of human immunodeficiency virus (HIV).
Synonyms:exact_synonym: dimethyl (3S,8S,9S,12S)-9-benzyl-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-6-[4-(2-pyridyl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate
 related_synonym: ATZ;   Formula=C38H52N6O7;   InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1;   InChIKey=AXRYRYVKAWYZBR-GASGPIRDSA-N;   SMILES=COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(cc1)-c1ccccn1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C;   atazanavirum
 xref: CAS:198904-31-3 "ChemIDplus";   DrugBank:DB01072;   KEGG:D07471
 xref_mesh: MESH:C413408
 xref: PMID:15156449 "Europe PMC";   PMID:15353575 "Europe PMC";   PMID:15645003 "Europe PMC";   PMID:15737947 "Europe PMC";   PMID:17376023 "Europe PMC";   PMID:17619250 "Europe PMC";   PMID:18389089 "Europe PMC";   PMID:24108452 "Europe PMC";   PMID:24314017 "Europe PMC";   PMID:25017682 "Europe PMC";   Reaxys:8101951 "Reaxys";   Wikipedia:Atazanavir

show annotations for term's descendants       view all columns           Sort by:
atazanavir sulfate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        antimicrobial agent 17158
          antiviral agent 3606
            antiviral drug 1648
              atazanavir 8
                atazanavir sulfate 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            heteroorganic entity 19012
                              organonitrogen compound 18089
                                carbohydrazide 716
                                  atazanavir 8
                                    atazanavir sulfate 8
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.