CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: pentane
Accession: CHEBI:37830
browse the term
Definition: A straight chain alkane consisting of 5 carbon atoms.
Synonyms: related_synonym: CH3-[CH2]3-CH3; Formula=C5H12; InChI=1S/C5H12/c1-3-5-4-2/h3-5H2,1-2H3; InChIKey=OFBQJSOFQDEBGM-UHFFFAOYSA-N; Pentan; R-601; SMILES=CCCCC; n-pentane
alt_id: CHEBI:25888; CHEBI:25889; CHEBI:43771
xref: Beilstein:969132; CAS:109-66-0; Gmelin:1766; HMDB:HMDB0029603
xref_mesh: MESH:C033353
xref: PDBeChem:LNK; PMID:14664856; PMID:24284369; PMID:24702114; Wikipedia:Pentane
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
pentane results in increased expression of BAX mRNA
CTD
PMID:33064461
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Cebpb
CCAAT/enhancer binding protein beta
decreases expression
ISO
pentane results in decreased expression of CEBPB mRNA
CTD
PMID:33064461
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Fn1
fibronectin 1
decreases expression
ISO
pentane results in decreased expression of FN1 mRNA
CTD
PMID:33064461
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Gng12
G protein subunit gamma 12
decreases expression
ISO
pentane results in decreased expression of GNG12 mRNA
CTD
PMID:33064461
NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712
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Acaa2
acetyl-CoA acyltransferase 2
multiple interactions increases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of ACAA2 mRNA di-n-pentyl phthalate results in increased expression of ACAA2 mRNA
CTD
PMID:25055962 PMID:33983380
NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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Acox1
acyl-CoA oxidase 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of ACOX1 mRNA
CTD
PMID:33983380
NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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Acsl1
acyl-CoA synthetase long-chain family member 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of ACSL1 mRNA
CTD
PMID:33983380
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl3
acyl-CoA synthetase long-chain family member 3
increases expression
EXP
di-n-pentyl phthalate results in increased expression of ACSL3 mRNA
CTD
PMID:33983380
NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Akr1b8
aldo-keto reductase family 1, member B8
increases expression
EXP
di-n-pentyl phthalate results in increased expression of AKR1B8 mRNA
CTD
PMID:19560483
NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
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Angptl4
angiopoietin-like 4
increases expression
EXP
di-n-pentyl phthalate results in increased expression of ANGPTL4 mRNA
CTD
PMID:33983380
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Aqp7
aquaporin 7
increases expression
EXP
di-n-pentyl phthalate results in increased expression of AQP7 mRNA
CTD
PMID:33983380
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
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Ar
androgen receptor
affects binding multiple interactions
ISO
di-n-pentyl phthalate binds to AR protein di-n-pentyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
CTD
PMID:14751673 PMID:15840436 PMID:28571686 PMID:33049310
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of ATP1A1 mRNA
CTD
PMID:19560483
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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Bcl2
BCL2, apoptosis regulator
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of BCL2 mRNA; di-n-pentyl phthalate results in decreased expression of BCL2 protein
CTD
PMID:33798595
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bmp6
bone morphogenetic protein 6
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of BMP6 mRNA
CTD
PMID:19560483
NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression
EXP
di-n-pentyl phthalate results in increased expression of CPT1A mRNA
CTD
PMID:33983380
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Cpt1b
carnitine palmitoyltransferase 1B
increases expression
EXP
di-n-pentyl phthalate results in increased expression of CPT1B mRNA
CTD
PMID:33983380
NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
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Cpt2
carnitine palmitoyltransferase 2
increases expression
EXP
di-n-pentyl phthalate results in increased expression of CPT2 mRNA
CTD
PMID:33983380
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
multiple interactions increases expression decreases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11A1 mRNA di-n-pentyl phthalate results in increased expression of CYP11A1 mRNA di-n-pentyl phthalate results in decreased expression of CYP11A1 mRNA
CTD
PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 More...
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
decreases expression multiple interactions
EXP
di-n-pentyl phthalate results in decreased expression of CYP11B1 mRNA [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B1 mRNA
CTD
PMID:22112501 PMID:25055962 PMID:33983380
NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
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Cyp11b3
cytochrome P450, family 11, subfamily b, polypeptide 3
decreases expression multiple interactions
EXP
di-n-pentyl phthalate results in decreased expression of CYP11B2 mRNA [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B2 mRNA
CTD
PMID:22112501 PMID:25055962 PMID:33983380
NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases activity decreases expression multiple interactions
EXP
di-n-pentyl phthalate results in decreased activity of CYP17A1 protein di-n-pentyl phthalate results in decreased expression of CYP17A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP17A1 protein [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA
CTD
PMID:6829050 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 More...
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of CYP19A1 mRNA
CTD
PMID:19560483
NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of CYP27A1 mRNA
CTD
PMID:26472102
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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Cyp51
cytochrome P450, family 51
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of CYP51 mRNA
CTD
PMID:26472102 PMID:33983380
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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Dhcr7
7-dehydrocholesterol reductase
multiple interactions decreases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of DHCR7 mRNA di-n-pentyl phthalate results in decreased expression of DHCR7 mRNA
CTD
PMID:22112501 PMID:25055962 PMID:33983380
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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Ebp
EBP, cholestenol delta-isomerase
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of EBP mRNA
CTD
PMID:26472102 PMID:33983380
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
increases expression
EXP
di-n-pentyl phthalate results in increased expression of EHHADH mRNA
CTD
PMID:33983380
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Esr1
estrogen receptor 1
affects binding multiple interactions
ISO
di-n-pentyl phthalate analog binds to ESR1 protein; di-n-pentyl phthalate binds to ESR1 protein di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein; di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Tamoxifen inhibits the reaction [di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein]
CTD
PMID:15464722 PMID:15840436 PMID:20822795 PMID:28571686 PMID:33049310
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
multiple interactions affects binding
ISO
di-n-pentyl phthalate binds to and results in decreased activity of ESR2 protein; di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein] di-n-pentyl phthalate analog binds to ESR2 protein
CTD
PMID:15464722 PMID:15840436 PMID:28571686
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Fabp1
fatty acid binding protein 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of FABP1 mRNA
CTD
PMID:33983380
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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Fads2
fatty acid desaturase 2
increases expression
EXP
di-n-pentyl phthalate results in increased expression of FADS2 mRNA
CTD
PMID:33983380
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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Fgfr2
fibroblast growth factor receptor 2
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of FGFR2 mRNA
CTD
PMID:26472102
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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Fsd2
fibronectin type III and SPRY domain containing 2
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of FSD2 mRNA
CTD
PMID:26472102
NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472
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Gata4
GATA binding protein 4
increases expression
EXP
di-n-pentyl phthalate results in increased expression of GATA4 mRNA
CTD
PMID:22112501
NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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Gnrhr
gonadotropin releasing hormone receptor
increases expression
EXP
di-n-pentyl phthalate results in increased expression of GNRHR mRNA
CTD
PMID:33798595
NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
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Grb14
growth factor receptor bound protein 14
increases expression
EXP
di-n-pentyl phthalate results in increased expression of GRB14 mRNA
CTD
PMID:15728792
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
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Hey1
hes-related family bHLH transcription factor with YRPW motif 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HEY1 mRNA
CTD
PMID:26472102
NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HMGCR mRNA
CTD
PMID:33983380
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HMGCS1 mRNA
CTD
PMID:33983380
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
increases expression
EXP
di-n-pentyl phthalate results in increased expression of HMGCS2 mRNA
CTD
PMID:33983380
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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Hnf1a
HNF1 homeobox A
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HNF1A mRNA
CTD
PMID:15728792
NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
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Hoxa1
homeobox A1
multiple interactions
ISO
di-n-pentyl phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]
CTD
PMID:23696197
NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HSD11B2 mRNA
CTD
PMID:19560483
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
increases expression
EXP
di-n-pentyl phthalate results in increased expression of HSD17B11 mRNA
CTD
PMID:26472102
NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
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Hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HSD17B3 mRNA; di-n-pentyl phthalate results in decreased expression of HSD17B3 protein
CTD
PMID:33798595
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
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Hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
increases expression
EXP
di-n-pentyl phthalate results in increased expression of HSD17B8 mRNA
CTD
PMID:19560483 PMID:26472102
NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
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Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HSD3B1 mRNA; di-n-pentyl phthalate results in decreased expression of HSD3B1 protein
CTD
PMID:33798595
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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Hsd3b3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of HSD3B3 mRNA
CTD
PMID:33983380
NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
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Id1
inhibitor of DNA binding 1, HLH protein
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of ID1 mRNA
CTD
PMID:26472102
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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Igf1
insulin-like growth factor 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of IGF1 mRNA
CTD
PMID:26472102
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igfbp7
insulin-like growth factor binding protein 7
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of IGFBP7 mRNA
CTD
PMID:19560483
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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Inha
inhibin subunit alpha
multiple interactions decreases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INHA mRNA di-n-pentyl phthalate results in decreased expression of INHA mRNA
CTD
PMID:25055962 PMID:26472102 PMID:33983380
NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
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Insig1
insulin induced gene 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of INSIG1 mRNA
CTD
PMID:15728792 PMID:33983380
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Insl3
insulin-like 3
multiple interactions decreases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INSL3 mRNA di-n-pentyl phthalate results in decreased expression of INSL3 mRNA
CTD
PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26454885 PMID:33798595 PMID:33983380 More...
NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
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Ldlr
low density lipoprotein receptor
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of LDLR mRNA
CTD
PMID:15728792 PMID:33983380
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lhb
luteinizing hormone subunit beta
decreases expression decreases secretion
EXP
di-n-pentyl phthalate results in decreased expression of LHB mRNA di-n-pentyl phthalate results in decreased secretion of LHB protein
CTD
PMID:33798595
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Lhcgr
luteinizing hormone/choriogonadotropin receptor
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of LHCGR mRNA; di-n-pentyl phthalate results in decreased expression of LHCGR protein
CTD
PMID:15728792 PMID:33798595 PMID:33983380
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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Msh2
mutS homolog 2
decreases expression increases expression
EXP
di-n-pentyl phthalate results in decreased expression of MSH2 mRNA di-n-pentyl phthalate results in increased expression of MSH2 mRNA
CTD
PMID:26472102
NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of MVD mRNA
CTD
PMID:33983380
NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
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Myocd
myocardin
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of MYOCD mRNA
CTD
PMID:26472102
NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
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Nr0b1
nuclear receptor subfamily 0, group B, member 1
decreases expression multiple interactions
EXP
di-n-pentyl phthalate results in decreased expression of NR0B1 mRNA [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of NR0B1 mRNA
CTD
PMID:15728792 PMID:22112501 PMID:25055962 PMID:33983380
NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
di-n-pentyl phthalate binds to and results in increased activity of NR1I2 protein
CTD
PMID:33049310
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects binding increases activity
ISO
di-n-pentyl phthalate analog binds to NR1I3 protein; di-n-pentyl phthalate binds to NR1I3 protein di-n-pentyl phthalate results in increased activity of NR1I3 protein
CTD
PMID:25938866 PMID:28927721
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of NR4A1 mRNA
CTD
PMID:15728792
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of NR4A3 mRNA
CTD
PMID:19560483
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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Nsdhl
NAD(P) dependent steroid dehydrogenase-like
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of NSDHL mRNA
CTD
PMID:19560483 PMID:33983380
NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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Pck1
phosphoenolpyruvate carboxykinase 1
increases expression
EXP
di-n-pentyl phthalate results in increased expression of PCK1 mRNA
CTD
PMID:33983380
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Ppara
peroxisome proliferator activated receptor alpha
affects binding
ISO
di-n-pentyl phthalate binds to PPARA protein
CTD
PMID:23843199
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Ppard
peroxisome proliferator-activated receptor delta
affects binding
ISO
di-n-pentyl phthalate binds to PPARB protein
CTD
PMID:23843199
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
affects binding multiple interactions
ISO
di-n-pentyl phthalate binds to PPARG protein di-n-pentyl phthalate binds to and results in increased activity of PPARG protein
CTD
PMID:23843199 PMID:33049310
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Rhox10
reproductive homeobox 10
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of RHOX10 mRNA
CTD
PMID:22112501
NCBI chr X:116,850,460...116,854,898
Ensembl chr X:116,850,460...116,854,941
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Rxra
retinoid X receptor alpha
affects binding
ISO
di-n-pentyl phthalate binds to RXRA protein
CTD
PMID:23843199
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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Rxrb
retinoid X receptor beta
affects binding
ISO
di-n-pentyl phthalate binds to RXRB protein
CTD
PMID:23843199
NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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Rxrg
retinoid X receptor gamma
affects binding
ISO
di-n-pentyl phthalate binds to RXRG protein
CTD
PMID:23843199
NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
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Scarb1
scavenger receptor class B, member 1
multiple interactions decreases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SCARB1 mRNA di-n-pentyl phthalate results in decreased expression of SCARB1 mRNA; di-n-pentyl phthalate results in decreased expression of SCARB1 protein
CTD
PMID:19560483 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 More...
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Scd
stearoyl-CoA desaturase
increases expression
EXP
di-n-pentyl phthalate results in increased expression of SCD mRNA
CTD
PMID:33983380
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Sirt1
sirtuin 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of SIRT1 protein
CTD
PMID:33798595
NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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Slc27a2
solute carrier family 27 member 2
increases expression
EXP
di-n-pentyl phthalate results in increased expression of SLC27A2 mRNA
CTD
PMID:33983380
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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Snx17
sorting nexin 17
multiple interactions
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SNX17 mRNA
CTD
PMID:25055962
NCBI chr 6:25,177,528...25,183,001
Ensembl chr 6:25,177,391...25,183,030
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Sox9
SRY-box transcription factor 9
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of SOX9 mRNA
CTD
PMID:26472102
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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Srd5a1
steroid 5 alpha-reductase 1
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of SRD5A1 mRNA
CTD
PMID:19560483
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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Star
steroidogenic acute regulatory protein
multiple interactions increases expression decreases expression
EXP
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of STAR mRNA di-n-pentyl phthalate results in increased expression of STAR mRNA di-n-pentyl phthalate results in decreased expression of STAR mRNA; di-n-pentyl phthalate results in decreased expression of STAR protein
CTD
PMID:19560483 PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 More...
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Tcf21
transcription factor 21
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of TCF21 mRNA
CTD
PMID:26472102
NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202
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Wnt7a
Wnt family member 7A
decreases expression
EXP
di-n-pentyl phthalate results in decreased expression of WNT7A mRNA
CTD
PMID:33983380
NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981
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Chrna2
cholinergic receptor nicotinic alpha 2 subunit
multiple interactions
ISO
n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]
CTD
PMID:11821649
NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
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Chrnb4
cholinergic receptor nicotinic beta 4 subunit
multiple interactions
ISO
n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]
CTD
PMID:11821649
NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
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Adam10
ADAM metallopeptidase domain 10
increases expression
EXP
2,3-pentanedione results in increased expression of ADAM10 mRNA
CTD
PMID:25710175
NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
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Adam19
ADAM metallopeptidase domain 19
increases expression
EXP
2,3-pentanedione results in increased expression of ADAM19 mRNA
CTD
PMID:25710175
NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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Adam8
ADAM metallopeptidase domain 8
decreases expression
EXP
2,3-pentanedione results in decreased expression of ADAM8 mRNA
CTD
PMID:25710175
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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Akap5
A-kinase anchoring protein 5
increases expression
EXP
2,3-pentanedione results in increased expression of AKAP5 mRNA
CTD
PMID:25710175
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Akr1b1
aldo-keto reductase family 1 member B1
increases reduction multiple interactions
ISO
AKR1B1 protein results in increased reduction of 2,3-pentanedione [AKR1B1 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of Pentanones
CTD
PMID:23295224
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr1b10
aldo-keto reductase family 1 member B10
increases reduction multiple interactions
ISO
AKR1B10 protein results in increased reduction of 2,3-pentanedione [AKR1B10 protein results in increased reduction of 2,3-pentanedione] which results in increased chemical synthesis of Pentanones
CTD
PMID:23295224
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Akr1b8
aldo-keto reductase family 1, member B8
multiple interactions
EXP
[AKR1B8 protein co-treated with NADP] affects the reduction of 2,3-pentanedione
CTD
PMID:18845131
NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
2,3-pentanedione results in increased expression of ALDH1A3 mRNA
CTD
PMID:30710127
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Angptl4
angiopoietin-like 4
increases expression
EXP
2,3-pentanedione results in increased expression of ANGPTL4 mRNA
CTD
PMID:25710175
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Apln
apelin
increases expression
EXP
2,3-pentanedione results in increased expression of APLN mRNA
CTD
PMID:25710175
NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391
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Arhgap17
Rho GTPase activating protein 17
increases expression
EXP
2,3-pentanedione results in increased expression of ARHGAP17 mRNA
CTD
PMID:25710175
NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
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Bcat1
branched chain amino acid transaminase 1
increases expression
EXP
2,3-pentanedione results in increased expression of BCAT1 mRNA
CTD
PMID:25710175
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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Bmp3
bone morphogenetic protein 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of BMP3 mRNA
CTD
PMID:25710175
NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
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C9
complement C9
decreases expression
EXP
2,3-pentanedione results in decreased expression of C9 mRNA
CTD
PMID:25710175
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
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Cc2d2a
coiled-coil and C2 domain containing 2A
decreases expression
ISO
2,3-pentanedione results in decreased expression of CC2D2A mRNA
CTD
PMID:30710127
NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
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Ccn2
cellular communication network factor 2
increases expression
EXP
2,3-pentanedione results in increased expression of CCN2 mRNA
CTD
PMID:25710175
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccn4
cellular communication network factor 4
increases expression
EXP
2,3-pentanedione results in increased expression of CCN4 mRNA
CTD
PMID:25710175
NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
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Cd36
CD36 molecule
increases expression
EXP
2,3-pentanedione results in increased expression of CD36 mRNA
CTD
PMID:25710175
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdc20b
cell division cycle 20B
decreases expression
ISO
2,3-pentanedione results in decreased expression of CDC20B mRNA
CTD
PMID:30710127
NCBI chr 2:44,688,349...44,738,056
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Cdhr4
cadherin-related family member 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of CDHR4 mRNA
CTD
PMID:25710175
NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367
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Ces1d
carboxylesterase 1D
decreases expression
EXP
2,3-pentanedione results in decreased expression of CES1D mRNA
CTD
PMID:25710175
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Cfap221
cilia and flagella associated protein 221
decreases expression
ISO
2,3-pentanedione results in decreased expression of CFAP221 mRNA
CTD
PMID:30710127
NCBI chr13:31,046,550...31,118,141
Ensembl chr13:31,046,535...31,116,899
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Cfap70
cilia and flagella associated protein 70
decreases expression
ISO
2,3-pentanedione results in decreased expression of CFAP70 mRNA
CTD
PMID:30710127
NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014
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Cldn18
claudin 18
increases expression
EXP
2,3-pentanedione results in increased expression of CLDN18 mRNA
CTD
PMID:25710175
NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
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Clic5
chloride intracellular channel 5
increases expression
EXP
2,3-pentanedione results in increased expression of CLIC5 mRNA
CTD
PMID:25710175
NCBI chr 9:16,710,980...16,813,427
Ensembl chr 9:16,710,980...16,813,427
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Cma1
chymase 1
increases expression
EXP
2,3-pentanedione results in increased expression of CMA1 mRNA
CTD
PMID:25710175
NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
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Col12a1
collagen type XII alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL12A1 mRNA
CTD
PMID:25710175
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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Col13a1
collagen type XIII alpha 1 chain
decreases expression
EXP
2,3-pentanedione results in decreased expression of COL13A1 mRNA
CTD
PMID:25710175
NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032
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Col14a1
collagen type XIV alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL14A1 mRNA
CTD
PMID:25710175
NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
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Col18a1
collagen type XVIII alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL18A1 mRNA
CTD
PMID:25710175
NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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Col1a2
collagen type I alpha 2 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL1A2 mRNA
CTD
PMID:25710175
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Col4a1
collagen type IV alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL4A1 mRNA
CTD
PMID:25710175
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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Col5a1
collagen type V alpha 1 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL5A1 mRNA
CTD
PMID:25710175
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Col5a2
collagen type V alpha 2 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL5A2 mRNA
CTD
PMID:25710175
NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
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Col5a3
collagen type V alpha 3 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL5A3 mRNA
CTD
PMID:25710175
NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853
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Col6a2
collagen type VI alpha 2 chain
increases expression
EXP
2,3-pentanedione results in increased expression of COL6A2 mRNA
CTD
PMID:25710175
NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
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Cpxm2
carboxypeptidase X (M14 family), member 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of CPXM2 mRNA
CTD
PMID:30710127
NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220
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Crabp2
cellular retinoic acid binding protein 2
increases expression
EXP
2,3-pentanedione results in increased expression of CRABP2 mRNA
CTD
PMID:25710175
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Csf3
colony stimulating factor 3
decreases expression
ISO
2,3-pentanedione results in decreased expression of CSF3 mRNA
CTD
PMID:30710127
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Cthrc1
collagen triple helix repeat containing 1
increases expression
EXP
2,3-pentanedione results in increased expression of CTHRC1 mRNA
CTD
PMID:25710175
NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756
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Cx3cr1
C-X3-C motif chemokine receptor 1
increases expression
EXP
2,3-pentanedione results in increased expression of CX3CR1 mRNA
CTD
PMID:25710175
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Cxcl1
C-X-C motif chemokine ligand 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of CXCL1 mRNA
CTD
PMID:25710175
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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Cxcl3
C-X-C motif chemokine ligand 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of CXCL3 mRNA
CTD
PMID:25710175
NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression increases expression
EXP
2,3-pentanedione results in decreased expression of CXCR4 mRNA 2,3-pentanedione results in increased expression of CXCR4 mRNA
CTD
PMID:25710175
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp2a3
cytochrome P450, family 2, subfamily a, polypeptide 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP2A3 mRNA
CTD
PMID:25710175
NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP2B1 mRNA
CTD
PMID:25710175
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP2F4 mRNA
CTD
PMID:25710175
NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of CYP4B1 mRNA
CTD
PMID:25710175
NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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Dhrs9
dehydrogenase/reductase 9
increases expression
ISO
2,3-pentanedione results in increased expression of DHRS9 mRNA
CTD
PMID:30710127
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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Dmrt2
doublesex and mab-3 related transcription factor 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of DMRT2 mRNA
CTD
PMID:25710175
NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131
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Dnaaf1
dynein, axonemal, assembly factor 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAAF1 mRNA
CTD
PMID:30710127
NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313
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Dnah12
dynein, axonemal, heavy chain 12
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAH12 mRNA
CTD
PMID:30710127
NCBI chr16:1,936,354...2,092,663
Ensembl chr16:1,937,817...2,092,664
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Dnah3
dynein, axonemal, heavy chain 3
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAH3 mRNA
CTD
PMID:30710127
NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474
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Dnah6
dynein, axonemal, heavy chain 6
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAH6 mRNA
CTD
PMID:30710127
NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376
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Dnai1
dynein, axonemal, intermediate chain 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of DNAI1 mRNA
CTD
PMID:30710127
NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
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Egfr
epidermal growth factor receptor
increases expression
EXP
2,3-pentanedione results in increased expression of EGFR mRNA
CTD
PMID:25710175
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Egr2
early growth response 2
increases expression
EXP
2,3-pentanedione results in increased expression of EGR2 mRNA
CTD
PMID:25710175
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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Fbln1
fibulin 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of FBLN1 mRNA
CTD
PMID:25710175
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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Fbn1
fibrillin 1
increases expression
EXP
2,3-pentanedione results in increased expression of FBN1 mRNA
CTD
PMID:25710175
NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
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Fgfr2
fibroblast growth factor receptor 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of FGFR2 mRNA
CTD
PMID:25710175
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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Fgfr3
fibroblast growth factor receptor 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of FGFR3 mRNA
CTD
PMID:25710175
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
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Fmo2
flavin containing dimethylaniline monoxygenase 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of FMO2 mRNA
CTD
PMID:25710175
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
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Fn1
fibronectin 1
increases expression
EXP
2,3-pentanedione results in increased expression of FN1 mRNA
CTD
PMID:25710175
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Fndc3b
fibronectin type III domain containing 3B
decreases expression
EXP
2,3-pentanedione results in decreased expression of FNDC3B mRNA
CTD
PMID:25710175
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
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Gad1
glutamate decarboxylase 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of GAD1 mRNA
CTD
PMID:25710175
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
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Gas6
growth arrest specific 6
increases expression
EXP
2,3-pentanedione results in increased expression of GAS6 mRNA
CTD
PMID:25710175
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
G
Ghitm
growth hormone inducible transmembrane protein
decreases expression
EXP
2,3-pentanedione results in decreased expression of GHITM mRNA
CTD
PMID:25710175
NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
G
Gpr155
G protein-coupled receptor 155
decreases expression
EXP
2,3-pentanedione results in decreased expression of GPR155 mRNA
CTD
PMID:25710175
NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275
G
Gpx2
glutathione peroxidase 2
increases expression
ISO
2,3-pentanedione results in increased expression of GPX2 mRNA
CTD
PMID:30710127
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Grb10
growth factor receptor bound protein 10
increases expression
EXP
2,3-pentanedione results in increased expression of GRB10 mRNA
CTD
PMID:25710175
NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
G
Gsta5
glutathione S-transferase alpha 5
decreases expression
EXP
2,3-pentanedione results in decreased expression of GSTA5 mRNA
CTD
PMID:25710175
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Hap1
huntingtin-associated protein 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of HAP1 mRNA
CTD
PMID:25710175
NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
G
Has2
hyaluronan synthase 2
increases expression
EXP
2,3-pentanedione results in increased expression of HAS2 mRNA
CTD
PMID:25710175
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
EXP
2,3-pentanedione results in increased expression of HBEGF mRNA
CTD
PMID:25710175
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
G
Hdac10
histone deacetylase 10
increases expression
EXP
2,3-pentanedione results in increased expression of HDAC10 mRNA
CTD
PMID:25710175
NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
G
Igf1
insulin-like growth factor 1
increases expression
EXP
2,3-pentanedione results in increased expression of IGF1 mRNA
CTD
PMID:25710175
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
increases expression
EXP
2,3-pentanedione results in increased expression of IGF2BP2 mRNA
CTD
PMID:25710175
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
G
Igfbp4
insulin-like growth factor binding protein 4
increases expression
EXP
2,3-pentanedione results in increased expression of IGFBP4 mRNA
CTD
PMID:25710175
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
G
Igfbp5
insulin-like growth factor binding protein 5
decreases expression
EXP
2,3-pentanedione results in decreased expression of IGFBP5 mRNA
CTD
PMID:25710175
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
G
Il18
interleukin 18
increases expression
EXP
2,3-pentanedione results in increased expression of IL18 mRNA
CTD
PMID:25710175
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1a
interleukin 1 alpha
increases expression
EXP
2,3-pentanedione results in increased expression of IL1A mRNA
CTD
PMID:25710175
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1rn
interleukin 1 receptor antagonist
increases expression
EXP
2,3-pentanedione results in increased expression of IL1RN mRNA
CTD
PMID:25710175
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
G
Il24
interleukin 24
increases expression
EXP
2,3-pentanedione results in increased expression of IL24 mRNA
CTD
PMID:25710175
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
G
Il33
interleukin 33
increases expression decreases expression
EXP ISO
2,3-pentanedione results in increased expression of IL33 mRNA 2,3-pentanedione results in decreased expression of IL33 mRNA
CTD
PMID:25710175 PMID:30710127
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
G
Inhba
inhibin subunit beta A
increases expression
EXP
2,3-pentanedione results in increased expression of INHBA mRNA
CTD
PMID:25710175
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
G
Irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of IRAK1BP1 mRNA
CTD
PMID:25710175
NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
G
Itga5
integrin subunit alpha 5
increases expression
EXP
2,3-pentanedione results in increased expression of ITGA5 mRNA
CTD
PMID:25710175
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
G
Itga6
integrin subunit alpha 6
increases expression
EXP
2,3-pentanedione results in increased expression of ITGA6 mRNA
CTD
PMID:25710175
NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
G
Itgb1
integrin subunit beta 1
increases expression
EXP
2,3-pentanedione results in increased expression of ITGB1 mRNA
CTD
PMID:25710175
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
G
Itgb3
integrin subunit beta 3
increases expression
EXP
2,3-pentanedione results in increased expression of ITGB3 mRNA
CTD
PMID:25710175
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
G
Klhl38
kelch-like family member 38
decreases expression
EXP
2,3-pentanedione results in decreased expression of KLHL38 mRNA
CTD
PMID:25710175
NCBI chr 7:89,854,015...89,864,352
Ensembl chr 7:89,855,148...89,864,276
G
Krt13
keratin 13
increases expression
ISO
2,3-pentanedione results in increased expression of KRT13 mRNA
CTD
PMID:30710127
NCBI chr10:85,052,122...85,056,032
Ensembl chr10:85,051,889...85,056,084
G
Krt14
keratin 14
increases expression
ISO
2,3-pentanedione results in increased expression of KRT14 mRNA
CTD
PMID:30710127
NCBI chr10:85,137,932...85,141,990
Ensembl chr10:85,066,802...85,171,799
G
Krt16
keratin 16
increases expression
ISO
2,3-pentanedione results in increased expression of KRT16 mRNA
CTD
PMID:30710127
NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
G
Krt4
keratin 4
increases expression
ISO
2,3-pentanedione results in increased expression of KRT4 mRNA
CTD
PMID:30710127
NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
G
Lamb3
laminin subunit beta 3
increases expression
EXP
2,3-pentanedione results in increased expression of LAMB3 mRNA
CTD
PMID:25710175
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
G
Lamc2
laminin subunit gamma 2
increases expression
EXP
2,3-pentanedione results in increased expression of LAMC2 mRNA
CTD
PMID:25710175
NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
G
Lamc3
laminin subunit gamma 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of LAMC3 mRNA
CTD
PMID:25710175
NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697
G
Lgi1
leucine-rich, glioma inactivated 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of LGI1 mRNA
CTD
PMID:25710175
NCBI chr 1:236,043,376...236,084,270
Ensembl chr 1:236,042,954...236,084,616
G
Lox
lysyl oxidase
increases expression
EXP
2,3-pentanedione results in increased expression of LOX mRNA
CTD
PMID:25710175
NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
G
Loxl2
lysyl oxidase-like 2
increases expression
EXP
2,3-pentanedione results in increased expression of LOXL2 mRNA
CTD
PMID:25710175
NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
G
Lrp10
LDL receptor related protein 10
increases expression
EXP
2,3-pentanedione results in increased expression of LRP10 mRNA
CTD
PMID:25710175
NCBI chr15:27,921,105...27,927,507
Ensembl chr15:27,920,259...27,927,505
G
Mmp14
matrix metallopeptidase 14
increases expression
EXP
2,3-pentanedione results in increased expression of MMP14 mRNA
CTD
PMID:25710175
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
G
Mmp2
matrix metallopeptidase 2
increases expression
EXP
2,3-pentanedione results in increased expression of MMP2 mRNA
CTD
PMID:25710175
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp24
matrix metallopeptidase 24
decreases expression
EXP
2,3-pentanedione results in decreased expression of MMP24 mRNA
CTD
PMID:25710175
NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
G
Ngf
nerve growth factor
increases expression
EXP
2,3-pentanedione results in increased expression of NGF mRNA
CTD
PMID:25710175
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
G
Nkain1
Sodium/potassium transporting ATPase interacting 1
increases expression
EXP
2,3-pentanedione results in increased expression of NKAIN1 mRNA
CTD
PMID:25710175
NCBI chr 5:142,747,702...142,792,665
Ensembl chr 5:142,747,505...142,791,863
G
Nog
noggin
increases expression
EXP
2,3-pentanedione results in increased expression of NOG mRNA
CTD
PMID:25710175
NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
G
Nrg1
neuregulin 1
increases expression
EXP
2,3-pentanedione results in increased expression of NRG1 mRNA
CTD
PMID:25710175
NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
G
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of PAPSS2 mRNA
CTD
PMID:30710127
NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
G
Pdgfrb
platelet derived growth factor receptor beta
increases expression
EXP
2,3-pentanedione results in increased expression of PDGFRB mRNA
CTD
PMID:25710175
NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
G
Plat
plasminogen activator, tissue type
increases expression
EXP
2,3-pentanedione results in increased expression of PLAT mRNA
CTD
PMID:25710175
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plau
plasminogen activator, urokinase
increases expression
EXP
2,3-pentanedione results in increased expression of PLAU mRNA
CTD
PMID:25710175
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
G
Plaur
plasminogen activator, urokinase receptor
increases expression
EXP
2,3-pentanedione results in increased expression of PLAUR mRNA
CTD
PMID:25710175
NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
G
Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
increases expression
EXP
2,3-pentanedione results in increased expression of PLOD2 mRNA
CTD
PMID:25710175
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
G
Pon1
paraoxonase 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of PON1 mRNA
CTD
PMID:25710175
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
G
Ppara
peroxisome proliferator activated receptor alpha
decreases expression
EXP
2,3-pentanedione results in decreased expression of PPARA mRNA
CTD
PMID:25710175
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Prom1
prominin 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of PROM1 mRNA
CTD
PMID:30710127
NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
G
Prss22
serine protease 22
increases expression
EXP
2,3-pentanedione results in increased expression of PRSS22 mRNA
CTD
PMID:25710175
NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of PTGS2 mRNA
CTD
PMID:30710127
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
G
Pthlh
parathyroid hormone-like hormone
decreases expression
ISO
2,3-pentanedione results in decreased expression of PTHLH mRNA
CTD
PMID:30710127
NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
G
Rasgrp1
RAS guanyl releasing protein 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of RASGRP1 mRNA
CTD
PMID:25710175
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
G
S100a1
S100 calcium binding protein A1
decreases expression
EXP
2,3-pentanedione results in decreased expression of S100A1 mRNA
CTD
PMID:25710175
NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
G
S1pr1
sphingosine-1-phosphate receptor 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of S1PR1 mRNA
CTD
PMID:25710175
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
G
Sbp
spermine binding protein
decreases expression
EXP
2,3-pentanedione results in decreased expression of SBP mRNA
CTD
PMID:25710175
NCBI chr10:12,946,036...12,968,439
Ensembl chr10:12,946,036...12,968,439
G
Scgb1a1
secretoglobin family 1A member 1
increases expression
ISO
2,3-pentanedione results in increased expression of SCGB1A1 mRNA
CTD
PMID:30710127
NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
G
Sec14l3
SEC14-like lipid binding 3
decreases expression
EXP
2,3-pentanedione results in decreased expression of SEC14L3 mRNA
CTD
PMID:25710175
NCBI chr14:78,944,568...78,955,608
Ensembl chr14:78,912,750...78,956,099
G
Serpinb5
serpin family B member 5
decreases expression
EXP
2,3-pentanedione results in decreased expression of SERPINB5 mRNA
CTD
PMID:25710175
NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
G
Serpine1
serpin family E member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPINE1 mRNA
CTD
PMID:25710175
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Serpinf1
serpin family F member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPINF1 mRNA
CTD
PMID:25710175
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
G
Serping1
serpin family G member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPING1 mRNA
CTD
PMID:25710175
NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
G
Serpinh1
serpin family H member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SERPINH1 mRNA
CTD
PMID:25710175
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
G
Slc15a1
solute carrier family 15 member 1
increases expression
EXP
2,3-pentanedione results in increased expression of SLC15A1 mRNA
CTD
PMID:25710175
NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
G
Slc15a2
solute carrier family 15 member 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of SLC15A2 mRNA
CTD
PMID:25710175
NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
G
Slc23a1
solute carrier family 23 member 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of SLC23A1 mRNA
CTD
PMID:25710175
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
G
Sorcs2
sortilin-related VPS10 domain containing receptor 2
decreases expression
ISO
2,3-pentanedione results in decreased expression of SORCS2 mRNA
CTD
PMID:30710127
NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943
G
Sorl1
sortilin related receptor 1
decreases expression
EXP
2,3-pentanedione results in decreased expression of SORL1 mRNA
CTD
PMID:25710175
NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
G
Spag17
sperm associated antigen 17
decreases expression
ISO
2,3-pentanedione results in decreased expression of SPAG17 mRNA
CTD
PMID:30710127
NCBI chr 2:187,264,004...187,511,061
Ensembl chr 2:187,264,009...187,510,501
G
Spon1
spondin 1
increases expression
EXP
2,3-pentanedione results in increased expression of SPON1 mRNA
CTD
PMID:25710175
NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
G
Spp1
secreted phosphoprotein 1
increases expression
EXP
2,3-pentanedione results in increased expression of SPP1 mRNA
CTD
PMID:25710175
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
G
Spr
sepiapterin reductase
decreases expression
EXP
2,3-pentanedione results in decreased expression of SPR mRNA
CTD
PMID:25710175
NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
G
Stra6
signaling receptor and transporter of retinol STRA6
decreases expression
EXP
2,3-pentanedione results in decreased expression of STRA6 mRNA
CTD
PMID:25710175
NCBI chr 8:58,549,743...58,568,861
Ensembl chr 8:58,549,736...58,568,860
G
Tekt1
tektin 1
decreases expression
ISO
2,3-pentanedione results in decreased expression of TEKT1 mRNA
CTD
PMID:30710127
NCBI chr10:56,952,164...56,980,572
Ensembl chr10:56,952,167...56,980,572
G
Tgfb2
transforming growth factor, beta 2
increases expression
EXP
2,3-pentanedione results in increased expression of TGFB2 mRNA
CTD
PMID:25710175
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
G
Tgfbi
transforming growth factor, beta induced
increases expression
EXP
2,3-pentanedione results in increased expression of TGFBI mRNA
CTD
PMID:25710175
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
G
Tgm1
transglutaminase 1
increases expression
EXP
2,3-pentanedione results in increased expression of TGM1 mRNA
CTD
PMID:25710175
NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
G
Thbs2
thrombospondin 2
increases expression
EXP
2,3-pentanedione results in increased expression of THBS2 mRNA
CTD
PMID:25710175
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
G
Thbs4
thrombospondin 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of THBS4 mRNA
CTD
PMID:25710175
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
G
Timp1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
2,3-pentanedione results in increased expression of TIMP1 mRNA
CTD
PMID:25710175
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Timp2
TIMP metallopeptidase inhibitor 2
increases expression
EXP
2,3-pentanedione results in increased expression of TIMP2 mRNA
CTD
PMID:25710175
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
G
Timp4
TIMP metallopeptidase inhibitor 4
decreases expression
EXP
2,3-pentanedione results in decreased expression of TIMP4 mRNA
CTD
PMID:25710175
NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
G
Tlr2
toll-like receptor 2
decreases expression
EXP
2,3-pentanedione results in decreased expression of TLR2 mRNA
CTD
PMID:25710175
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
G
Tmem178a
transmembrane protein 178A
increases expression
EXP
2,3-pentanedione results in increased expression of TMEM178 mRNA
CTD
PMID:25710175
NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549
G
Tnc
tenascin C
increases expression
EXP
2,3-pentanedione results in increased expression of TNC mRNA
CTD
PMID:25710175
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
G
Tnfaip6
TNF alpha induced protein 6
increases expression
EXP
2,3-pentanedione results in increased expression of TNFAIP6 mRNA
CTD
PMID:25710175
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
G
Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
EXP
2,3-pentanedione results in increased expression of TNFRSF12A mRNA
CTD
PMID:25710175
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
G
Tnn
tenascin N
increases expression
EXP
2,3-pentanedione results in increased expression of TNN mRNA
CTD
PMID:25710175
NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156
G
Ubr2
ubiquitin protein ligase E3 component n-recognin 2
increases expression
EXP
2,3-pentanedione results in increased expression of UBR2 mRNA
CTD
PMID:25710175
NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
G
Zfp318
zinc finger protein 318
increases expression
EXP
2,3-pentanedione results in increased expression of ZFP318 mRNA
CTD
PMID:25710175
NCBI chr 9:14,562,958...14,601,557
Ensembl chr 9:14,563,313...14,601,409
G
Zfp853
zinc finger protein 853
decreases expression
EXP
2,3-pentanedione results in decreased expression of ZFP853 mRNA
CTD
PMID:25710175
NCBI chr12:11,266,124...11,276,492
Ensembl chr12:11,269,414...11,275,731
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