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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkali metal hydride
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Accession:CHEBI:37760 term browser browse the term


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lithium hydride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA] CTD PMID:19149911 NCBI chr10:105,568,091...105,572,407
Ensembl chr10:105,568,091...105,572,403
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP Lithium results in increased expression of ABCB1B mRNA; Lithium results in increased expression of ABCB1B protein CTD PMID:19570321 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA] CTD PMID:19149911 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Actb actin, beta increases expression EXP Lithium results in increased expression of ACTB protein CTD PMID:18296634 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actr3 actin related protein 3 increases expression EXP Lithium results in increased expression of ACTR3 protein CTD PMID:18296634 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Adk adenosine kinase increases expression EXP Lithium results in increased expression of ADK protein CTD PMID:18296634 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adnp2 ADNP homeobox 2 increases expression ISO Lithium results in increased expression of ADNP2 mRNA CTD PMID:19949822 NCBI chr18:76,637,415...76,661,186
Ensembl chr18:76,637,785...76,653,056
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
increases expression
ISO Lithium results in increased phosphorylation of AKT1 protein
Lithium results in increased expression of AKT1 mRNA; Lithium results in increased expression of AKT1 protein
CTD PMID:19440698 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression EXP Lithium results in decreased expression of ALDH1A3 protein CTD PMID:18296634 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 increases expression ISO Lithium results in increased expression of ANTXR2 mRNA CTD PMID:21092101 NCBI chr14:13,191,716...13,331,286
Ensembl chr14:13,192,347...13,274,978
JBrowse link
G Anxa2 annexin A2 decreases expression EXP Lithium results in decreased expression of ANXA2 protein CTD PMID:18296634 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa4 annexin A4 increases expression EXP Lithium results in increased expression of ANXA4 protein CTD PMID:18296634 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa5 annexin A5 increases expression EXP Lithium results in increased expression of ANXA5 protein CTD PMID:18296634 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO
EXP
Lithium inhibits the reaction [APP protein binds to APP protein]
Lithium inhibits the reaction [APP protein alternative form results in decreased expression of BCL2 protein]
CTD PMID:10762662, PMID:19621015 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aprt adenine phosphoribosyl transferase increases expression EXP Lithium results in increased expression of APRT protein CTD PMID:18296634 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp2 aquaporin 2 multiple interactions
decreases expression
increases expression
ISO
EXP
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]; PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of AQP2 protein]
Lithium results in increased expression of AQP2 protein
Lithium results in decreased expression of AQP2 mRNA; Lithium results in decreased expression of AQP2 protein
[Aldosterone co-treated with Lithium] affects the expression of AQP2 protein; [Spironolactone co-treated with Lithium] affects the expression of AQP2 protein; Hydrochlorothiazide inhibits the reaction [Lithium results in decreased expression of AQP2 protein]
CTD PMID:7535800, PMID:10966935, PMID:12472779, PMID:14613889, PMID:15153756, PMID:15504936, PMID:16159898, PMID:16434572, PMID:16495377, PMID:18296634, PMID:19244398, PMID:25006961 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP Lithium results in decreased expression of AQP3 protein CTD PMID:10966935 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp6 aquaporin 6 increases expression EXP Lithium results in increased expression of AQP6 mRNA; Lithium results in increased expression of AQP6 protein CTD PMID:11097619 NCBI chr 7:141,258,585...141,261,518
Ensembl chr 7:141,258,584...141,261,735
JBrowse link
G Arg2 arginase 2 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP [Lithium co-treated with Pilocarpine] results in decreased expression of ATF2 protein CTD PMID:19430551 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO Lithium results in decreased expression of ATM mRNA CTD PMID:19949822 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression
increases expression
multiple interactions
EXP
ISO
Lithium results in decreased expression of ATP1A1 mRNA
Lithium results in increased expression of ATP1A1 protein
Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 mRNA]; Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 protein]
CTD PMID:15153756, PMID:18296634, PMID:19995221 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A2 mRNA] CTD PMID:19995221 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] CTD PMID:19149911 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP Lithium results in increased expression of ATP5F1B protein CTD PMID:18296634 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression EXP Lithium results in increased expression of ATP5F1D protein CTD PMID:18296634 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Avp arginine vasopressin affects expression
increases expression
multiple interactions
EXP Lithium affects the expression of AVP protein
Lithium results in increased expression of AVP protein
Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein]
CTD PMID:2454589, PMID:3976404 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bag1 BAG cochaperone 1 increases expression EXP Lithium results in increased expression of BAG1 mRNA; Lithium results in increased expression of BAG1 protein CTD PMID:15872096 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
Lithium inhibits the reaction [sodium arsenite affects the localization of BAX protein]; Lithium inhibits the reaction [sodium arsenite promotes the reaction [BAX protein binds to BAX protein]]
Lithium inhibits the reaction [Cadmium results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Morphine results in increased expression of BAX mRNA]
Lithium results in decreased expression of BAX mRNA
CTD PMID:17849503, PMID:18976035, PMID:19149911, PMID:19949822, PMID:20455018 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
Lithium inhibits the reaction [Ethanol results in decreased expression of BCL2 mRNA]
Lithium results in increased expression of BCL2; Lithium results in increased expression of BCL2 mRNA; Lithium results in increased expression of BCL2 protein
Lithium inhibits the reaction [APP protein alternative form results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Cadmium results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Morphine results in decreased expression of BCL2 mRNA]
CTD PMID:10762662, PMID:15581403, PMID:16288908, PMID:18976035, PMID:19149911, PMID:20455018, PMID:21878650 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor affects response to substance
increases expression
decreases expression
multiple interactions
increases response to substance
ISO
EXP
BDNF gene polymorphism affects the susceptibility to Lithium
Lithium results in increased expression of BDNF mRNA; Lithium results in increased expression of BDNF protein
Lithium results in decreased expression of BDNF mRNA
Diazepam inhibits the reaction [Lithium results in increased expression of BDNF mRNA]; Lithium inhibits the reaction [Dextroamphetamine results in decreased expression of BDNF protein]; Lithium inhibits the reaction [Ouabain results in decreased expression of BDNF protein]
BDNF protein results in increased susceptibility to Lithium
CTD PMID:9073163, PMID:16460767, PMID:17442489, PMID:19018715, PMID:19954800, PMID:21220416 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Lithium results in increased expression of BIRC5 mRNA CTD PMID:16288908 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression EXP Lithium results in increased expression of BUB1B mRNA CTD PMID:21711903 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Calr calreticulin increases expression EXP Lithium results in increased expression of CALR mRNA; Lithium results in increased expression of CALR protein CTD PMID:16236328 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases expression EXP Lithium results in increased expression of CAMK4 mRNA; Lithium results in increased expression of CAMK4 protein CTD PMID:19711354 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression EXP Lithium results in increased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Lithium results in increased expression of CA2 protein CTD PMID:18296634 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp12 caspase 12 multiple interactions EXP [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein; Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein] CTD PMID:21429313 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
EXP
ISO
[Pilocarpine co-treated with Lithium] results in increased activity of CASP3 protein; Lithium inhibits the reaction [Cadmium results in increased expression of CASP3 protein]; Lithium inhibits the reaction [Colchicine results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]
Lithium results in decreased activity of CASP3 protein
Lithium inhibits the reaction [Monensin results in increased activity of CASP3 protein]; Lithium inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]
CTD PMID:15005753, PMID:15581403, PMID:17849503, PMID:20149694, PMID:20455018, PMID:20799912 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA] CTD PMID:19149911 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Lithium inhibits the reaction [Monensin results in increased activity of CASP7 protein] CTD PMID:20799912 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Lithium inhibits the reaction [Camptothecin results in increased activity of CASP8 protein]; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein] CTD PMID:15475000 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase increases activity
multiple interactions
ISO
EXP
Lithium results in increased activity of CAT protein
Lithium inhibits the reaction [Ouabain results in decreased activity of CAT protein]
CTD PMID:18187119, PMID:20627318 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccna1 cyclin A1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] CTD PMID:19149911 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnb2 cyclin B2 increases expression EXP Lithium results in increased expression of CCNB2 mRNA CTD PMID:21711903 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA] CTD PMID:19149911 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Lithium inhibits the reaction [Ethanol results in decreased expression of CCND2 mRNA] CTD PMID:21878650 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression EXP Lithium results in decreased expression of CD151 mRNA CTD PMID:11682256 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression EXP Lithium results in increased expression of CDCA3 mRNA CTD PMID:21711903 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdh1 cadherin 1 increases expression EXP Lithium results in increased expression of CDH1 protein CTD PMID:18296634 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein] CTD PMID:11337498 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression EXP Lithium results in decreased expression of CDKN1B mRNA; Lithium results in decreased expression of CDKN1B protein CTD PMID:15687245, PMID:18296634 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cfl1 cofilin 1 increases expression EXP Lithium results in increased expression of CFL1 protein CTD PMID:18296634 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Ckb creatine kinase B increases expression EXP Lithium results in increased expression of CKB protein CTD PMID:18296634 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression EXP Lithium results in increased expression of COX5A protein CTD PMID:18296634 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression EXP Lithium results in increased expression of COX5B protein CTD PMID:18296634 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Crip1 cysteine rich protein 1 increases expression ISO Lithium results in increased expression of CRIP1 mRNA CTD PMID:21092101 NCBI chr 6:137,959,171...137,967,042
Ensembl chr 6:137,959,171...137,967,042
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP Lithium results in decreased expression of CRYAB protein CTD PMID:18296634 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
decreases expression
multiple interactions
affects localization
ISO
EXP
Lithium results in increased expression of CTNNB1 protein
Lithium results in decreased expression of CTNNB1 mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA]; Lithium results in increased expression of and affects the localization of CTNNB1 protein
Lithium affects the localization of CTNNB1 protein
CTD PMID:12942141, PMID:16288908, PMID:18296634, PMID:19149911, PMID:19621015 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsd cathepsin D increases expression EXP Lithium results in increased expression of CTSD protein CTD PMID:18296634 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression ISO Lithium results in decreased expression of DDR2 mRNA CTD PMID:21092101 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddx21 DExD-box helicase 21 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] CTD PMID:19149911 NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632
JBrowse link
G Drd1 dopamine receptor D1 affects response to substance
increases response to substance
ISO DRD1 gene polymorphism affects the susceptibility to Lithium
DRD1 protein results in increased susceptibility to Lithium
CTD PMID:19153942 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP Lithium results in decreased expression of DRD2 protein CTD PMID:16478526 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Lithium results in increased expression of DUSP1 mRNA CTD PMID:21092101 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dynlrb1 dynein light chain roadblock-type 1 increases expression EXP Lithium results in increased expression of DYNLRB1 protein CTD PMID:18296634 NCBI chr 3:150,761,329...150,782,493
Ensembl chr 3:150,761,329...150,782,493
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Lithium results in increased expression of ECH1 protein CTD PMID:18296634 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Ect2 epithelial cell transforming 2 increases expression EXP Lithium results in increased expression of ECT2 mRNA CTD PMID:21711903 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression EXP Lithium results in increased expression of EEF1A1 protein CTD PMID:18296634 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eif3k eukaryotic translation initiation factor 3, subunit K increases expression EXP Lithium results in increased expression of EIF3K protein CTD PMID:18296634 NCBI chr 1:87,927,142...87,937,033
Ensembl chr 1:87,927,141...87,937,516
JBrowse link
G Etfb electron transfer flavoprotein subunit beta increases expression EXP Lithium results in increased expression of ETFB protein CTD PMID:18296634 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Ezr ezrin increases expression EXP Lithium results in increased expression of EZR mRNA; Lithium results in increased expression of EZR protein CTD PMID:15687245, PMID:18296634 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Lithium inhibits the reaction [Camptothecin results in increased expression of and affects the localization of FAS protein]; Lithium inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein] CTD PMID:15475000 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Lithium results in increased expression of FOS mRNA
Lithium results in increased expression of FOS protein
[Pilocarpine co-treated with Lithium] results in increased expression of FOS protein; Lithium promotes the reaction [Pilocarpine results in increased expression of FOS mRNA]
CTD PMID:7984056, PMID:8511714, PMID:9630518, PMID:11739594, PMID:17962567, PMID:21092101 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Lithium results in increased expression of FOSB mRNA CTD PMID:21092101 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Lithium inhibits the reaction [Cadmium results in decreased expression of FSHB protein] CTD PMID:20455018 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP Lithium results in increased expression of FTL protein CTD PMID:18296634 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA] CTD PMID:19149911 NCBI chr11:24,293,845...24,322,822
Ensembl chr11:24,263,281...24,322,815
JBrowse link
G Galm galactose mutarotase decreases expression EXP Lithium results in decreased expression of GALM protein CTD PMID:18296634 NCBI chr 6:2,808,988...2,860,742
Ensembl chr 6:2,808,841...2,860,744
JBrowse link
G Ganab glucosidase II alpha subunit increases expression EXP Lithium results in increased expression of GANAB protein CTD PMID:18296634 NCBI chr 1:225,096,558...225,116,384
Ensembl chr 1:225,096,598...225,116,378
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased expression of GDNF protein CTD PMID:12914250 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Lithium results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gls glutaminase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA] CTD PMID:19149911 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression
multiple interactions
EXP Lithium results in decreased expression of GOT2 protein
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA]
CTD PMID:18296634, PMID:19149911 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases activity EXP Lithium results in increased activity of GPD1 protein CTD PMID:3224025 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA] CTD PMID:19149911 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Lithium results in decreased expression of GRIA1 protein CTD PMID:18171924 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions
decreases expression
EXP [Lithium co-treated with Pilocarpine] results in increased expression of GRIA2 mRNA
Lithium results in decreased expression of GRIA2 protein
CTD PMID:16819974, PMID:18171924 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions EXP [Lithium co-treated with Pilocarpine] results in decreased expression of GRIA3 mRNA CTD PMID:16819974 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 decreases expression
multiple interactions
ISO
EXP
Lithium results in decreased expression of GRIK2 mRNA; Lithium results in decreased expression of GRIK2 protein
[Lithium co-treated with Pilocarpine] results in increased expression of GRIK2 mRNA
CTD PMID:16819974, PMID:19596362 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions EXP [Lithium co-treated with Pilocarpine] results in decreased expression of GRIK5 mRNA CTD PMID:16819974 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased phosphorylation of GRIN2A protein CTD PMID:16600505 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased phosphorylation of GRIN2B protein CTD PMID:16600505 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions
EXP
ISO
Lithium results in increased expression of GSK3A protein
Lithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3A protein]
CTD PMID:17849503, PMID:18296634 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
decreases activity
decreases phosphorylation
increases expression
ISO
EXP
Lithium results in increased phosphorylation of GSK3B protein
Lithium inhibits the reaction [GSK3B protein binds to TP53 protein]; Lithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3B protein]; Magnesium affects the reaction [Lithium results in decreased activity of GSK3B protein]
Lithium results in decreased phosphorylation of GSK3B protein
Lithium results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium results in increased expression of GSK3B mRNA; Lithium results in increased expression of GSK3B protein
[Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein; [Lithium results in decreased activity of GSK3B protein] which results in increased activity of NFE2L2 protein; Lithium results in increased phosphorylation of and results in decreased activity of GSK3B protein
CTD PMID:10998351, PMID:15475000, PMID:15950778, PMID:16288908, PMID:17849503, PMID:17921520, PMID:18296634, PMID:18619545, PMID:19328817, PMID:19359144, PMID:19440698, PMID:19621015, PMID:21711903, PMID:25433145 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GSTA3 mRNA] CTD PMID:19149911 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Lithium results in increased expression of GSTA4 mRNA CTD PMID:18082333 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Lithium results in increased expression of GSTM1 mRNA; Lithium results in increased expression of GSTM1 protein CTD PMID:18082333, PMID:18296634 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression EXP Lithium results in increased expression of GSTM5 mRNA CTD PMID:18082333 NCBI chr 2:210,761,729...210,766,501
Ensembl chr 2:210,761,729...210,766,501
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression EXP Lithium results in increased expression of GSTM3 mRNA CTD PMID:18082333 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Lithium results in increased expression of GSTP1 protein CTD PMID:18296634 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hhex hematopoietically expressed homeobox multiple interactions
affects expression
ISO Folic Acid inhibits the reaction [Lithium affects the expression of HHEX mRNA]; Inositol promotes the reaction [Folic Acid inhibits the reaction [Lithium affects the expression of HHEX mRNA]] CTD PMID:19638421 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Lithium results in decreased expression of HILPDA mRNA CTD PMID:21092101 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Lithium results in increased expression of HMOX1 protein CTD PMID:18619545 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Homer3 homer scaffold protein 3 decreases expression ISO Lithium results in decreased expression of HOMER3 mRNA CTD PMID:19949822 NCBI chr16:20,880,447...20,890,968
Ensembl chr16:20,881,518...20,890,949
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP Lithium results in increased expression of HPRT1 protein CTD PMID:18296634 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression EXP Lithium results in increased expression of HSD11B2 mRNA; Lithium results in increased expression of HSD11B2 protein CTD PMID:15687245 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 increases expression EXP Lithium results in increased expression of HSD17B10 protein CTD PMID:18296634 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression EXP Lithium results in increased expression of HSP90B1 mRNA; Lithium results in increased expression of HSP90B1 protein CTD PMID:16236328, PMID:18296634 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP Lithium results in increased expression of HSPA1B protein CTD PMID:18296634 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases expression EXP Lithium results in decreased expression of HSPA1L protein CTD PMID:18296634 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP [Pilocarpine co-treated with Lithium] results in increased expression of HSPA5 mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of HSPA5 protein; Edaravone promotes the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of HSPA5 protein]
Lithium results in increased expression of HSPA5 mRNA; Lithium results in increased expression of HSPA5 protein
CTD PMID:16236328, PMID:18296634, PMID:21429313 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression
multiple interactions
EXP Lithium results in increased expression of HSPA9 protein
Lithium inhibits the reaction [Methamphetamine results in increased expression of HSPA9 mRNA]
CTD PMID:18296634, PMID:19149911 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein] CTD PMID:31760073 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO Lithium inhibits the reaction [Olanzapine results in decreased expression of IL10 protein]
Lithium results in increased expression of IL10 mRNA
CTD PMID:30695037 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Lithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:19159680 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO [Pilocarpine co-treated with Lithium] results in increased expression of IL1B mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of IL1B protein; Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of IL1B mRNA]; Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of IL1B protein]
Lithium results in increased expression of IL1B protein
Lithium inhibits the reaction [Olanzapine results in increased expression of IL1B mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL1B protein]
Lithium results in decreased expression of IL1B mRNA
CTD PMID:19951488, PMID:30695037 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases expression ISO Lithium results in increased expression of IL2 protein CTD PMID:10880530 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
EXP Lithium results in increased expression of IL4 protein
Lithium inhibits the reaction [Cadmium results in decreased expression of IL4 protein]
CTD PMID:20455018 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Lithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL6 mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL6 protein]
Lithium results in increased expression of IL6 mRNA
CTD PMID:19159680, PMID:30695037 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Impa1 inositol monophosphatase 1 decreases response to substance ISO IMPA1 protein results in decreased susceptibility to Lithium CTD PMID:17460611 NCBI chr 2:93,675,203...93,696,355
Ensembl chr 2:93,675,203...93,696,232
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased expression of JUN protein; Lithium promotes the reaction [Pilocarpine results in increased expression of JUN mRNA] CTD PMID:7984056, PMID:19430551 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Lithium promotes the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7984056 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kif20a kinesin family member 20A increases expression EXP Lithium results in increased expression of KIF20A mRNA CTD PMID:21711903 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif23 kinesin family member 23 increases expression EXP Lithium results in increased expression of KIF23 mRNA CTD PMID:21711903 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Kifc1 kinesin family member C1 increases expression EXP Lithium results in increased expression of KIFC1 mRNA CTD PMID:21711903 NCBI chr20:5,509,059...5,526,175
Ensembl chr20:5,509,059...5,526,175
JBrowse link
G Klf6 Kruppel-like factor 6 affects expression ISO Lithium affects the expression of KLF6 mRNA CTD PMID:21092101 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Lithium inhibits the reaction [Cadmium results in decreased expression of LHB protein] CTD PMID:20455018 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lmna lamin A/C increases expression EXP Lithium results in increased expression of LMNA protein CTD PMID:18296634 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO [Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein] which results in increased phosphorylation of MAP2K1 protein CTD PMID:19159680 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases degradation
multiple interactions
ISO Lithium results in increased degradation of MAP3K8 protein alternative form
[Lithium results in increased degradation of NFKB1 protein] inhibits the reaction [NFKB1 protein binds to MAP3K8 protein]; [Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein] which results in increased phosphorylation of MAP2K1 protein; Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP3K8 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein
CTD PMID:19159680 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
increases activity
increases phosphorylation
ISO
EXP
Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAPK1 protein
Lithium results in increased expression of MAPK1 protein
Lithium results in increased activity of MAPK1 protein
Lithium results in increased phosphorylation of MAPK1 protein
CTD PMID:11756416, PMID:18296634, PMID:19159680 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
ISO Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAPK3 protein
Lithium results in increased activity of MAPK3 protein
CTD PMID:11756416, PMID:19159680 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
increases phosphorylation
EXP Lithium results in increased expression of MAPK8 protein
Lithium results in increased phosphorylation of MAPK8 protein
CTD PMID:18296634 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression EXP Lithium results in increased expression of MAPK9 protein CTD PMID:18296634 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mir497 microRNA 497 multiple interactions ISO Lithium inhibits the reaction [Ethanol results in increased expression of MIR497] CTD PMID:21878650 NCBI chr10:56,844,977...56,845,045
Ensembl chr10:56,844,977...56,845,045
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP Lithium results in increased expression of MKI67 mRNA CTD PMID:21711903 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL18 mRNA] CTD PMID:19149911 NCBI chr 1:48,033,531...48,038,726
Ensembl chr 1:48,033,768...48,038,726
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL53 mRNA] CTD PMID:19149911 NCBI chr 4:113,942,037...113,942,927
Ensembl chr 4:113,942,041...113,942,674
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein CTD PMID:17921520 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myl6 myosin light chain 6 decreases expression EXP Lithium results in decreased expression of MYL6 protein CTD PMID:18296634 NCBI chr 7:2,906,137...2,909,193
Ensembl chr 7:2,906,137...2,909,179
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
multiple interactions
ISO Lithium results in increased activity of NFE2L2 protein
[Lithium results in decreased activity of GSK3B protein] which results in increased activity of NFE2L2 protein
CTD PMID:18619545 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases degradation
multiple interactions
ISO Lithium results in increased degradation of NFKB1 protein
[Lithium results in increased degradation of NFKB1 protein] inhibits the reaction [NFKB1 protein binds to MAP3K8 protein]; Lithium inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased localization of NFKB1 protein]
CTD PMID:19159680 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Lithium results in increased expression of NME2 protein CTD PMID:18296634 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression
EXP [Pilocarpine co-treated with Lithium] results in increased expression of NOS1 protein; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of NOS1 protein]
Lithium results in increased expression of NOS1 mRNA
CTD PMID:11087959, PMID:20149694 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Pilocarpine co-treated with Lithium] results in increased expression of NOS2 protein; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of NOS2 protein] CTD PMID:20149694 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy neuropeptide Y increases expression EXP Lithium results in increased expression of NPY mRNA; Lithium results in increased expression of NPY protein CTD PMID:17572454 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 affects response to substance ISO NR1D1 gene polymorphism affects the susceptibility to Lithium CTD PMID:20348464 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Lithium inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]]; Lithium inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]
Lithium inhibits the reaction [Dexamethasone affects the localization of and results in increased activity of NR3C1 protein]
CTD PMID:15249158, PMID:15872096 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Lithium results in increased expression of NR4A2 mRNA CTD PMID:21092101 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nsfl1c NSFL1 cofactor increases expression EXP Lithium results in increased expression of NSFL1C protein CTD PMID:18296634 NCBI chr 3:146,980,923...147,005,478
Ensembl chr 3:146,980,923...147,005,439
JBrowse link
G Ntf3 neurotrophin 3 increases expression
multiple interactions
EXP Lithium results in increased expression of NTF3 protein
Lithium inhibits the reaction [Amphetamine affects the expression of NTF3 protein]
CTD PMID:17512948 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Nudt4 nudix hydrolase 4 increases expression EXP Lithium results in increased expression of NUDT4 mRNA CTD PMID:11331144 NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Lithium results in decreased expression of OGG1 mRNA CTD PMID:22641096 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide increases secretion
increases expression
EXP Lithium results in increased secretion of OXT protein
Lithium results in increased expression of OXT mRNA
CTD PMID:11739594 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 increases expression EXP Lithium results in increased expression of P2RY4 mRNA CTD PMID:19244398 NCBI chr  X:70,421,599...70,447,109
Ensembl chr  X:70,426,951...70,428,364
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Lithium inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:17849503 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 increases expression ISO Lithium results in increased expression of PARP4 mRNA CTD PMID:19949822 NCBI chr15:36,809,362...36,911,167 JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 increases expression ISO Lithium results in increased expression of PCMT1 mRNA CTD PMID:19949822 NCBI chr 1:1,734,863...1,767,759
Ensembl chr 1:1,736,276...1,767,618
JBrowse link
G Pdcd6 programmed cell death 6 increases expression EXP Lithium results in increased expression of PDCD6 protein CTD PMID:18296634 NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849
JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Lithium results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP Lithium results in decreased expression of PDE4B protein CTD PMID:20222156 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pde8b phosphodiesterase 8B decreases expression EXP Lithium results in decreased expression of PDE8B mRNA CTD PMID:20222156 NCBI chr 2:24,718,548...24,955,533
Ensembl chr 2:24,719,976...24,923,128
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression EXP Lithium results in increased expression of PDIA3 protein CTD PMID:18296634 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP Lithium results in increased expression of PEBP1 protein CTD PMID:18296634 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 increases expression ISO Lithium results in increased expression of PEX1 mRNA CTD PMID:19949822 NCBI chr 4:27,659,376...27,698,037
Ensembl chr 4:27,659,381...27,698,037
JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression EXP Lithium results in increased expression of PGAM1 protein CTD PMID:18296634 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Phb prohibitin increases expression EXP Lithium results in increased expression of PHB protein CTD PMID:18296634 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression ISO Lithium results in increased expression of PLA2G4A mRNA; Lithium results in increased expression of PLA2G4A protein CTD PMID:17594078 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pls3 plastin 3 increases expression EXP Lithium results in increased expression of PLS3 protein CTD PMID:18296634 NCBI chr  X:119,030,311...119,124,268
Ensembl chr  X:119,030,419...119,124,250
JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO [Guanosine Triphosphate co-treated with Lithium] results in decreased activity of POMC protein modified form CTD PMID:2550106 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP Lithium results in increased expression of PPIA protein CTD PMID:18296634 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression EXP Lithium results in increased expression of PRDX5 protein CTD PMID:18296634 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
decreases response to substance
increases response to substance
ISO PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of AQP2 protein]; PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of SLC14A2 protein]
PRKCA gene mutant form results in decreased susceptibility to Lithium
PRKCA gene results in increased susceptibility to Lithium
CTD PMID:25006961 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of PRKCE mRNA] CTD PMID:19149911 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO Lithium inhibits the reaction [PRKCG protein mutant form binds to PRKCG protein mutant form] CTD PMID:20398063 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prl prolactin multiple interactions EXP Lithium inhibits the reaction [Cadmium results in increased expression of PRL protein] CTD PMID:20455018 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP Lithium results in increased expression of PSMB1 protein CTD PMID:18296634 NCBI chr 1:57,470,878...57,491,359
Ensembl chr 1:57,470,632...57,489,727
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP Lithium results in increased expression of PSMB9 protein CTD PMID:18296634 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 decreases expression ISO Lithium results in decreased expression of PSMD1 mRNA CTD PMID:19949822 NCBI chr 9:93,080,618...93,155,033
Ensembl chr 9:93,080,615...93,155,027
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 increases expression EXP Lithium results in increased expression of PSMD13 protein CTD PMID:18296634 NCBI chr 1:213,636,159...213,648,499
Ensembl chr 1:213,636,093...213,648,488
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 increases expression EXP Lithium results in increased expression of PSMD8 protein CTD PMID:18296634 NCBI chr 1:88,116,811...88,123,643
Ensembl chr 1:88,116,812...88,123,643
JBrowse link
G Psme2 proteasome activator subunit 2 increases expression EXP Lithium results in increased expression of PSME2 protein CTD PMID:18296634 NCBI chr15:34,265,552...34,269,851
Ensembl chr15:34,265,557...34,269,851
JBrowse link
G Pth parathyroid hormone increases expression EXP
ISO
Lithium results in increased expression of PTH protein CTD PMID:581022, PMID:7212107, PMID:8840263, PMID:10423626 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased activity of PTK2B protein CTD PMID:16600505 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of QARS1 mRNA] CTD PMID:19149911 NCBI chr 8:117,297,670...117,305,708
Ensembl chr 8:117,297,670...117,305,702
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression EXP Lithium results in increased expression of RACGAP1 mRNA CTD PMID:21711903 NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase decreases expression ISO Lithium results in decreased expression of RAD18 mRNA CTD PMID:22641096 NCBI chr 4:144,537,329...144,620,606
Ensembl chr 4:144,536,729...144,620,731
JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP Lithium results in increased expression of RAN protein CTD PMID:18296634 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Lithium promotes the reaction [Lipopolysaccharides results in increased localization of REL protein] CTD PMID:19159680 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity
ISO Lithium inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased localization of RELA protein]
Lithium results in increased activity of RELA protein
CTD PMID:11756416, PMID:19159680 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Reln reelin decreases expression EXP Lithium results in decreased expression of RELN mRNA; Lithium results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Ret ret proto-oncogene multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased expression of RET protein CTD PMID:12914250 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO Lithium results in increased expression of RGCC mRNA CTD PMID:21092101 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Lithium results in increased expression of RGS2 mRNA CTD PMID:21092101 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase increases expression ISO Lithium results in increased expression of RNMT mRNA CTD PMID:19949822 NCBI chr18:64,084,746...64,108,246
Ensembl chr18:64,084,795...64,108,246
JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression EXP Lithium results in decreased expression of S100A4 protein CTD PMID:18296634 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G S100a6 S100 calcium binding protein A6 decreases expression EXP Lithium results in decreased expression of S100A6 protein CTD PMID:18296634 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions ISO [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Lithium CTD PMID:18665318 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions ISO [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Lithium CTD PMID:18665318 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma affects expression
multiple interactions
EXP
ISO
Lithium affects the expression of SCNN1G protein
[SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Lithium
CTD PMID:12928314, PMID:18665318 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression EXP Lithium results in increased expression of SLC12A1 mRNA; Lithium results in increased expression of SLC12A1 protein CTD PMID:10966935, PMID:12472779 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc13a2 solute carrier family 13 member 2 multiple interactions ISO
EXP
Lithium inhibits the reaction [SLC13A2 protein results in increased uptake of Citric Acid]
Lithium promotes the reaction [SLC13A2 protein results in increased uptake of Citric Acid]
CTD PMID:12826022 NCBI chr10:65,664,665...65,692,046
Ensembl chr10:65,664,667...65,692,023
JBrowse link
G Slc14a2 solute carrier family 14 member 2 decreases expression
multiple interactions
ISO Lithium results in decreased expression of SLC14A2 protein
PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of SLC14A2 protein]
CTD PMID:25006961 NCBI chr18:74,508,070...74,941,389
Ensembl chr18:74,546,220...74,688,551
Ensembl chr18:74,546,220...74,688,551
JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Lithium results in increased expression of SLC17A6 mRNA; Lithium results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:106,980,463...107,038,717
Ensembl chr 1:106,998,623...107,038,704
JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression ISO Lithium results in increased expression of SLC17A7 mRNA; Lithium results in increased expression of SLC17A7 protein CTD PMID:16111724 NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174
JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions ISO Lithium promotes the reaction [SLC20A1 protein results in increased uptake of Phosphates] CTD PMID:17494632 NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
JBrowse link
G Slc20a2 solute carrier family 20 member 2 multiple interactions ISO Lithium promotes the reaction [SLC20A2 protein results in increased uptake of Phosphates] CTD PMID:17494632 NCBI chr16:74,318,287...74,408,030
Ensembl chr16:74,317,899...74,408,030
JBrowse link
G Slc9a1 solute carrier family 9 member A1 decreases expression
increases activity
multiple interactions
ISO Lithium results in decreased expression of SLC9A1 mRNA
Lithium results in increased activity of SLC9A1 protein
Phloretin inhibits the reaction [SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]]; SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]
CTD PMID:12765964, PMID:18506424 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Slc9a3 solute carrier family 9 member A3 increases expression EXP Lithium results in increased expression of SLC9A3 protein CTD PMID:10966935 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070
JBrowse link
G Slc9b2 solute carrier family 9 member B2 multiple interactions ISO SLC9B2 protein affects the transport of [Sodium co-treated with Lithium] CTD PMID:18000046 NCBI chr 2:240,485,254...240,519,166
Ensembl chr 2:240,495,371...240,519,141
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP Lithium results in decreased expression of SLCO1A4 mRNA CTD PMID:19570321 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slit2 slit guidance ligand 2 increases expression
decreases expression
EXP Lithium results in increased expression of SLIT2 protein
Lithium results in decreased expression of SLIT2 protein
CTD PMID:20153733 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Snca synuclein alpha multiple interactions EXP Lithium inhibits the reaction [Rotenone results in increased expression of and results in increased phosphorylation of SNCA protein] CTD PMID:25433145 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Cadmium results in decreased expression of SOD1 protein]
Lithium results in increased expression of SOD1 protein
CTD PMID:18296634, PMID:20455018 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in decreased activity of SOD2 protein] CTD PMID:31760073 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparcl1 SPARC like 1 affects localization EXP Lithium affects the localization of SPARCL1 protein CTD PMID:18488994 NCBI chr14:6,994,261...7,025,309
Ensembl chr14:6,994,190...7,025,308
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex increases expression EXP Lithium results in increased expression of SPC25 mRNA CTD PMID:21711903 NCBI chr 3:55,438,534...55,451,961
Ensembl chr 3:55,438,536...55,451,798
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased activity of SRC protein CTD PMID:16600505 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 increases expression EXP Lithium results in increased expression of SRCIN1 protein CTD PMID:18296634 NCBI chr10:85,460,059...85,517,671
Ensembl chr10:85,460,059...85,517,683
JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO Lithium results in decreased expression of STC2 mRNA CTD PMID:21092101 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression EXP Lithium results in increased expression of STIP1 protein CTD PMID:18296634 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression ISO Lithium results in decreased expression of SULT1A1 mRNA CTD PMID:19949822 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP [Pilocarpine co-treated with Lithium] results in increased expression of TAC1 mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of TAC1 protein modified form; Dizocilpine Maleate inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of TAC1 protein modified form] CTD PMID:11074153 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19149911 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP Lithium results in decreased expression of TJP1 protein CTD PMID:17533168 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tkt transketolase increases expression EXP Lithium results in increased expression of TKT protein CTD PMID:18296634 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tmx4 thioredoxin-related transmembrane protein 4 increases expression EXP Lithium results in increased expression of TMX4 protein CTD PMID:18296634 NCBI chr 3:127,528,427...127,569,093
Ensembl chr 3:127,528,434...127,569,093
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
EXP
ISO
Lithium inhibits the reaction [Cadmium results in increased expression of TNF protein]
Lithium inhibits the reaction [Olanzapine results in increased expression of TNF mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of TNF protein]
Lithium results in decreased expression of TNF mRNA
CTD PMID:20455018, PMID:30695037 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP Lithium results in increased expression of TOP2A mRNA CTD PMID:21711903 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein]
Lithium inhibits the reaction [GSK3B protein binds to TP53 protein]; Lithium inhibits the reaction [sodium arsenite results in increased expression of and affects the localization of TP53 protein]
CTD PMID:11337498, PMID:15475000, PMID:17849503 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Lithium results in increased expression of TPI1 protein CTD PMID:18296634 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Tpm1 tropomyosin 1 decreases expression EXP Lithium results in decreased expression of TPM1 protein CTD PMID:18296634 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases transport ISO TRPC6 protein results in increased transport of Lithium CTD PMID:11179201 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO Lithium inhibits the reaction [Monensin results in increased expression of TRPM2 protein alternative form] CTD PMID:20799912 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Ttk Ttk protein kinase increases expression EXP Lithium results in increased expression of TTK mRNA CTD PMID:21711903 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression EXP Lithium results in increased expression of UBE2C mRNA CTD PMID:21711903 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Uck1 uridine-cytidine kinase 1 increases expression EXP Lithium results in increased expression of UCK1 protein CTD PMID:18296634 NCBI chr 3:11,271,874...11,277,757
Ensembl chr 3:11,271,885...11,277,757
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 increases expression EXP Lithium results in increased expression of UHRF1 mRNA CTD PMID:21711903 NCBI chr 9:10,738,211...10,758,403
Ensembl chr 9:10,738,222...10,757,954
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 increases expression EXP Lithium results in increased expression of UQCRFS1 protein CTD PMID:18296634 NCBI chr17:35,677,984...35,682,262
Ensembl chr17:35,677,984...35,682,259
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
decreases expression
EXP
ISO
Lithium results in increased expression of VEGFA mRNA; Lithium results in increased expression of VEGFA protein
Lithium results in decreased expression of VEGFA mRNA
CTD PMID:16288908, PMID:17533168, PMID:19949822 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vps29 VPS29 retromer complex component increases expression EXP Lithium results in increased expression of VPS29 protein CTD PMID:18296634 NCBI chr12:39,690,069...39,699,114
Ensembl chr12:39,690,069...39,699,113
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon increases expression EXP Lithium results in increased expression of YWHAE protein CTD PMID:18296634 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta decreases expression EXP Lithium results in decreased expression of YWHAQ protein CTD PMID:18296634 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19769
      atom 19768
        main group element atom 19655
          alkali metal atom 10309
            alkali metal molecular entity 10284
              alkali metal hydride 245
                lithium hydrides + 245
                potassium hydride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19397
                        hydrogen molecular entity 19387
                          hydrides 18419
                            inorganic hydride 17380
                              metal hydride 313
                                alkali metal hydride 245
                                  lithium hydrides + 245
                                  potassium hydride 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.