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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:protein kinase inhibitor
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Accession:CHEBI:37699 term browser browse the term
Definition:An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Synonyms:related_synonym: protein kinase inhibitors
 alt_id: MESH:D047428
 xref_mesh: MESH:D047428



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    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19810
        role 19759
          biological role 19759
            biochemical role 19379
              enzyme inhibitor 18390
                EC 2.* (transferase) inhibitor 13902
                  EC 2.7.* (P-containing group transferase) inhibitor 13539
                    protein kinase inhibitor 13065
                      (+)-makassaric acid 0
                      (+)-subersic acid 0
                      1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 0
                      1,8-dihydroxy-4-nitroxanthen-9-one 0
                      2-(\{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl\}amino)benzamide 0
                      Aurora kinase inhibitor + 4029
                      CMB4563 0
                      CZC8004 0
                      DMH1 0
                      EC 2.7.10.* (protein-tyrosine kinase) inhibitor + 9388
                      EC 2.7.11.* (protein-serine/threonine kinase) inhibitor + 8193
                      EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor + 720
                      Ro 320-1195 + 0
                      XMD8-92 0
                      aminopurvalanol 0
                      epidermal growth factor receptor antagonist + 321
                      erlotinib + 130
                      erlotinib hydrochloride 130
                      gamma-mangostin 6
                      mTOR inhibitor + 500
                      miltefosine 2
                      pelitinib + 0
                      piceatannol + 0
                      purvalanol B 0
                      quercetin + 4028
                      salt-inducible kinase 2 inhibitor + 0
                      sangivamycin 0
                      tyrosine kinase inhibitor + 11403
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