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ONTOLOGY REPORT - ANNOTATIONS


Term:protein kinase inhibitor
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Accession:CHEBI:37699 term browser browse the term
Definition:An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Synonyms:related_synonym: protein kinase inhibitors
 alt_id: MESH:D047428
 xref_mesh: MESH:D047428


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  CHEBI ontology 19654
    role 19598
      biological role 19596
        biochemical role 19125
          enzyme inhibitor 17962
            EC 2.* (transferase) inhibitor 12148
              EC 2.7.* (P-containing group transferase) inhibitor 11800
                protein kinase inhibitor 11067
                  (+)-makassaric acid 0
                  (+)-subersic acid 0
                  1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 0
                  1,8-dihydroxy-4-nitroxanthen-9-one 0
                  2-(\{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl\}amino)benzamide 0
                  Aurora kinase inhibitor + 3990
                  CMB4563 0
                  CZC8004 0
                  DMH1 0
                  EC 2.7.10.* (protein-tyrosine kinase) inhibitor + 6164
                  EC 2.7.11.* (protein-serine/threonine kinase) inhibitor + 8099
                  EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor + 657
                  Ro 320-1195 + 0
                  XMD8-92 0
                  aminopurvalanol 0
                  epidermal growth factor receptor antagonist + 292
                  erlotinib + 121
                  erlotinib hydrochloride 121
                  gamma-mangostin 0
                  mTOR inhibitor + 465
                  miltefosine 2
                  pelitinib + 0
                  piceatannol + 0
                  purvalanol B 0
                  quercetin + 3989
                  salt-inducible kinase 2 inhibitor + 0
                  sangivamycin 0
                  tyrosine kinase inhibitor + 8546
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.