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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:clorgyline
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Accession:CHEBI:3763 term browser browse the term
Definition:An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.
Synonyms:exact_synonym: N-[3-(2,4-dichlorophenoxy)propyl]-N-methylprop-2-yn-1-amine
 related_synonym: Formula=C13H15Cl2NO;   InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3;   InChIKey=BTFHLQRNAMSNLC-UHFFFAOYSA-N;   M and B 9302;   M&B 9302;   N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-2-propynylamine;   N-methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine;   SMILES=CN(CCCOc1ccc(Cl)cc1Cl)CC#C;   clorgilina;   clorgiline;   clorgilinum
 xref: CAS:17780-72-2;   DrugBank:DB04017;   KEGG:C11685;   KEGG:D03248;   LINCS:LSM-5808
 xref_mesh: MESH:D003010
 xref: MetaCyc:CPD-7656;   PDBeChem:MLG;   PMID:21079379;   PMID:22203607;   PMID:23546802;   PMID:5119769;   Reaxys:1976758;   Wikipedia:Clorgiline



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clorgyline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 increases expression ISO Clorgyline results in increased expression of ABCA5 mRNA CTD PMID:19691856 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain increases expression ISO Clorgyline results in increased expression of ACADSB mRNA CTD PMID:19691856 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 increases expression ISO Clorgyline results in increased expression of ACAP2 mRNA CTD PMID:19691856 NCBI chr11:69,538,487...69,654,156
Ensembl chr11:69,538,546...69,654,151
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased expression of ACTA2 mRNA] CTD PMID:34609854 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression ISO Clorgyline results in increased expression of ADRB2 mRNA CTD PMID:19691856 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Akap11 A-kinase anchoring protein 11 increases expression ISO Clorgyline results in increased expression of AKAP11 mRNA CTD PMID:19691856 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
JBrowse link
G Akap9 A-kinase anchoring protein 9 increases expression ISO Clorgyline results in increased expression of AKAP9 mRNA CTD PMID:19691856 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Ankrd12 ankyrin repeat domain 12 increases expression ISO Clorgyline results in increased expression of ANKRD12 mRNA CTD PMID:19691856 NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911
JBrowse link
G Apc APC regulator of WNT signaling pathway increases expression ISO Clorgyline results in increased expression of APC mRNA CTD PMID:19691856 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Ar androgen receptor increases expression ISO Clorgyline results in increased expression of AR mRNA CTD PMID:19691856 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 increases expression ISO Clorgyline results in increased expression of ARAP2 mRNA CTD PMID:19691856 NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154
JBrowse link
G Arid4a AT-rich interaction domain 4A increases expression ISO Clorgyline results in increased expression of ARID4A mRNA CTD PMID:19691856 NCBI chr 6:89,522,463...89,593,868
Ensembl chr 6:89,522,442...89,593,510
JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase increases expression ISO Clorgyline results in increased expression of ATG4C mRNA CTD PMID:19691856 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Clorgyline results in increased expression of ATRX mRNA CTD PMID:19691856 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Azi2 5-azacytidine induced 2 increases expression ISO Clorgyline results in increased expression of AZI2 mRNA CTD PMID:19691856 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847
JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Clorgyline results in increased expression of B3GNT5 mRNA CTD PMID:19691856 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166
JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression ISO Clorgyline results in increased expression of BAZ2B mRNA CTD PMID:19691856 NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908
JBrowse link
G Bdp1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB increases expression ISO Clorgyline results in increased expression of BDP1 mRNA CTD PMID:19691856 NCBI chr 2:31,457,523...31,470,119
Ensembl chr 2:31,378,924...31,470,119
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 increases expression ISO Clorgyline results in increased expression of BOD1L1 mRNA CTD PMID:19691856 NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490
JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases expression ISO Clorgyline results in increased expression of BRWD1 mRNA CTD PMID:19691856 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 increases expression ISO Clorgyline results in increased expression of CACNB2 mRNA CTD PMID:19691856 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link
G Cbln2 cerebellin 2 precursor increases expression ISO Clorgyline results in increased expression of CBLN2 mRNA CTD PMID:19691856 NCBI chr18:79,940,412...79,948,766
Ensembl chr18:79,942,590...79,947,855
JBrowse link
G Ccdc112 coiled-coil domain containing 112 increases expression ISO Clorgyline results in increased expression of CCDC112 mRNA CTD PMID:19691856 NCBI chr18:38,998,139...39,032,329
Ensembl chr18:38,998,139...39,032,329
JBrowse link
G Cdh23 cadherin-related 23 increases expression ISO Clorgyline results in increased expression of CDH23 mRNA CTD PMID:19691856 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419
JBrowse link
G Cenpc centromere protein C increases expression ISO Clorgyline results in increased expression of CENPC mRNA CTD PMID:19691856 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
JBrowse link
G Cep135 centrosomal protein 135 increases expression ISO Clorgyline results in increased expression of CEP135 mRNA CTD PMID:19691856 NCBI chr14:31,530,538...31,595,718
Ensembl chr14:31,531,482...31,595,772
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO Clorgyline results in increased expression of CEP290 mRNA CTD PMID:19691856 NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392
JBrowse link
G Cep350 centrosomal protein 350 increases expression ISO Clorgyline results in increased expression of CEP350 mRNA CTD PMID:19691856 NCBI chr13:68,023,327...68,164,478
Ensembl chr13:68,026,891...68,165,214
JBrowse link
G Cep70 centrosomal protein 70 increases expression ISO Clorgyline results in increased expression of CEP70 mRNA CTD PMID:19691856 NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855
JBrowse link
G Cfh complement factor H increases expression ISO Clorgyline results in increased expression of CFH mRNA CTD PMID:19691856 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Chd9 chromodomain helicase DNA binding protein 9 increases expression ISO Clorgyline results in increased expression of CHD9 mRNA CTD PMID:19691856 NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
JBrowse link
G Chic1 cysteine-rich hydrophobic domain 1 increases expression ISO Clorgyline results in increased expression of CHIC1 mRNA CTD PMID:19691856 NCBI chr  X:68,362,001...68,406,155
Ensembl chr  X:68,361,969...68,437,887
JBrowse link
G Chm CHM Rab escort protein increases expression ISO Clorgyline results in increased expression of CHM mRNA CTD PMID:19691856 NCBI chr  X:78,203,200...78,361,996
Ensembl chr  X:78,203,204...78,361,943
JBrowse link
G Clgn calmegin increases expression ISO Clorgyline results in increased expression of CLGN mRNA CTD PMID:19691856 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Clorgyline results in increased expression of CLIP1 mRNA CTD PMID:19691856 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Cntn3 contactin 3 increases expression ISO Clorgyline results in increased expression of CNTN3 mRNA CTD PMID:19691856 NCBI chr 4:134,841,268...135,214,460
Ensembl chr 4:134,842,266...135,125,613
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Clorgyline results in increased expression of COBLL1 mRNA CTD PMID:19691856 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA] CTD PMID:34609854 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA] CTD PMID:34609854 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Cpd carboxypeptidase D increases expression ISO Clorgyline results in increased expression of CPD mRNA CTD PMID:19691856 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
JBrowse link
G Cpne9 copine family member 9 increases expression ISO Clorgyline results in increased expression of CPNE9 mRNA CTD PMID:19691856 NCBI chr 4:146,429,961...146,454,335
Ensembl chr 4:146,430,792...146,454,333
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
multiple interactions
ISO Clorgyline results in decreased activity of CYP2B6 protein
Clorgyline inhibits the reaction [CYP2B6 protein results in increased hydroxylation of Bupropion]
CTD PMID:25656918 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 increases expression ISO Clorgyline results in increased expression of DKKL1 mRNA CTD PMID:19691856 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259
JBrowse link
G Dmxl1 Dmx-like 1 increases expression ISO Clorgyline results in increased expression of DMXL1 mRNA CTD PMID:19691856 NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression ISO Clorgyline results in increased expression of DNAJC10 mRNA CTD PMID:19691856 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dst dystonin increases expression ISO Clorgyline results in increased expression of DST mRNA CTD PMID:19691856 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases expression ISO Clorgyline results in increased expression of DYNC2H1 mRNA CTD PMID:19691856 NCBI chr 8:4,189,257...4,412,183
Ensembl chr 8:4,189,257...4,412,183
JBrowse link
G Dync2li1 dynein cytoplasmic 2 light intermediate chain 1 increases expression ISO Clorgyline results in increased expression of DYNC2LI1 mRNA CTD PMID:19691856 NCBI chr 6:9,992,537...10,025,403
Ensembl chr 6:9,992,541...10,025,336
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 increases expression ISO Clorgyline results in increased expression of ECHDC1 mRNA CTD PMID:19691856 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319
JBrowse link
G Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 increases expression ISO Clorgyline results in increased expression of ESCO1 mRNA CTD PMID:19691856 NCBI chr18:1,630,560...1,686,803
Ensembl chr18:1,631,954...1,686,942
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO Clorgyline results in decreased expression of EZH2 mRNA CTD PMID:19691856 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Clorgyline results in increased expression of FAS mRNA CTD PMID:19691856 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fzd3 frizzled class receptor 3 increases expression ISO Clorgyline results in increased expression of FZD3 mRNA CTD PMID:19691856 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha increases expression ISO Clorgyline results in increased expression of GABPA mRNA CTD PMID:19691856 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Gap43 growth associated protein 43 decreases expression EXP Clorgyline results in decreased expression of GAP43 protein CTD PMID:12480131 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 increases expression ISO Clorgyline results in increased expression of GCC2 mRNA CTD PMID:19691856 NCBI chr20:26,247,394...26,293,613
Ensembl chr20:26,247,404...26,293,613
JBrowse link
G Gk glycerol kinase increases expression ISO Clorgyline results in increased expression of GK mRNA CTD PMID:19691856 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gnpda2 glucosamine-6-phosphate deaminase 2 increases expression ISO Clorgyline results in increased expression of GNPDA2 mRNA CTD PMID:19691856 NCBI chr14:38,520,663...38,538,713
Ensembl chr14:38,520,705...38,538,713
JBrowse link
G Golga4 golgin A4 increases expression ISO Clorgyline results in increased expression of GOLGA4 mRNA CTD PMID:19691856 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Golgb1 golgin B1 increases expression ISO Clorgyline results in increased expression of GOLGB1 mRNA CTD PMID:19691856 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain increases expression ISO Clorgyline results in increased expression of HBD mRNA CTD PMID:19691856 NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 increases expression ISO Clorgyline results in increased expression of HINT3 mRNA CTD PMID:19691856 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721
JBrowse link
G Ibtk inhibitor of Bruton tyrosine kinase increases expression ISO Clorgyline results in increased expression of IBTK mRNA CTD PMID:19691856 NCBI chr 8:86,625,591...86,698,661
Ensembl chr 8:86,625,597...86,698,260
JBrowse link
G Ift80 intraflagellar transport 80 increases expression ISO Clorgyline results in increased expression of IFT80 mRNA CTD PMID:19691856 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Clorgyline inhibits the reaction [Cisplatin results in increased secretion of IL1B protein] CTD PMID:34560070 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Klhdc1 kelch domain containing 1 increases expression ISO Clorgyline results in increased expression of KLHDC1 mRNA CTD PMID:19691856 NCBI chr 6:87,670,182...87,765,431
Ensembl chr 6:87,712,772...87,765,424
JBrowse link
G Klhl2 kelch-like family member 2 increases expression ISO Clorgyline results in increased expression of KLHL2 mRNA CTD PMID:19691856 NCBI chr16:24,860,763...24,973,348
Ensembl chr16:24,860,667...24,973,341
JBrowse link
G Ktn1 kinectin 1 increases expression ISO Clorgyline results in increased expression of KTN1 mRNA CTD PMID:19691856 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
JBrowse link
G Larp1b La ribonucleoprotein 1B increases expression ISO Clorgyline results in increased expression of LARP1B mRNA CTD PMID:19691856 NCBI chr 2:123,936,074...123,969,254
Ensembl chr 2:123,935,983...123,968,896
JBrowse link
G Lig4 DNA ligase 4 increases expression ISO Clorgyline results in increased expression of LIG4 mRNA CTD PMID:19691856 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G LOC120100466 small nucleolar RNA SNORD64 increases expression ISO Clorgyline results in increased expression of SNORD64 mRNA CTD PMID:19691856 NCBI chr 1:111,094,909...111,094,975
Ensembl chr 1:111,094,909...111,094,975
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression ISO Clorgyline results in increased expression of LRAT mRNA CTD PMID:19691856 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Ltb lymphotoxin beta increases expression ISO Clorgyline results in increased expression of LTB mRNA CTD PMID:19691856 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Manea mannosidase, endo-alpha increases expression ISO Clorgyline results in increased expression of MANEA mRNA CTD PMID:19691856 NCBI chr 5:40,196,373...40,218,534
Ensembl chr 5:40,196,396...40,218,459
JBrowse link
G Maoa monoamine oxidase A multiple interactions
decreases activity
ISO
EXP
[[Clorgyline results in decreased activity of MAOA protein] co-treated with [Pargyline results in decreased activity of MAOB protein]] inhibits the reaction [resveratrol promotes the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]]; [[Clorgyline results in decreased activity of MAOA protein] co-treated with [Pargyline results in decreased activity of MAOB protein]] promotes the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; [Clorgyline results in decreased activity of MAOA protein] which results in increased susceptibility to Methamphetamine
Clorgyline inhibits the reaction [MAOA protein results in increased degradation of Serotonin]
Phenylpropanolamine inhibits the reaction [Clorgyline results in decreased activity of MAOA protein]
CTD PMID:1905457 PMID:3961266 PMID:12818349 PMID:16252076 PMID:21923181 More... NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity
multiple interactions
ISO Clorgyline results in decreased activity of MAOB protein
[[Clorgyline results in decreased activity of MAOA protein] co-treated with [Pargyline results in decreased activity of MAOB protein]] inhibits the reaction [resveratrol promotes the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]]; [[Clorgyline results in decreased activity of MAOA protein] co-treated with [Pargyline results in decreased activity of MAOB protein]] promotes the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
CTD PMID:23499958 PMID:23943324 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map9 microtubule-associated protein 9 increases expression ISO Clorgyline results in increased expression of MAP9 mRNA CTD PMID:19691856 NCBI chr 2:167,708,661...167,743,927
Ensembl chr 2:167,708,765...167,740,736
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 increases expression ISO Clorgyline results in increased expression of MBNL2 mRNA CTD PMID:19691856 NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mia2 MIA SH3 domain ER export factor 2 increases expression ISO Clorgyline results in increased expression of MIA2 mRNA CTD PMID:19691856 NCBI chr 6:76,787,508...76,885,246
Ensembl chr 6:76,787,508...76,885,211
JBrowse link
G Mipol1 mirror-image polydactyly 1 increases expression ISO Clorgyline results in increased expression of MIPOL1 mRNA CTD PMID:19691856 NCBI chr 6:74,755,314...75,090,403
Ensembl chr 6:74,755,395...75,086,811
JBrowse link
G Mob1b MOB kinase activator 1B increases expression ISO Clorgyline results in increased expression of MOB1B mRNA CTD PMID:19691856 NCBI chr14:19,333,058...19,365,845
Ensembl chr14:19,332,459...19,365,845
JBrowse link
G Mon2 MON2 homolog, regulator of endosome-to-Golgi trafficking increases expression ISO Clorgyline results in increased expression of MON2 mRNA CTD PMID:19691856 NCBI chr 7:58,649,378...58,728,102
Ensembl chr 7:58,651,075...58,728,064
JBrowse link
G Mospd2 motile sperm domain containing 2 increases expression ISO Clorgyline results in increased expression of MOSPD2 mRNA CTD PMID:19691856 NCBI chr  X:29,420,484...29,472,099
Ensembl chr  X:29,420,586...29,462,398
JBrowse link
G Mpp7 MAGUK p55 scaffold protein 7 increases expression ISO Clorgyline results in increased expression of MPP7 mRNA CTD PMID:19691856 NCBI chr17:55,439,939...55,706,810
Ensembl chr17:55,442,696...55,706,748
JBrowse link
G Myo6 myosin VI increases expression ISO Clorgyline results in increased expression of MYO6 mRNA CTD PMID:19691856 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Ndfip2 Nedd4 family interacting protein 2 increases expression ISO Clorgyline results in increased expression of NDFIP2 mRNA CTD PMID:19691856 NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO Clorgyline results in increased expression of NFE2L2 mRNA CTD PMID:19691856 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nipbl NIPBL, cohesin loading factor increases expression ISO Clorgyline results in increased expression of NIPBL mRNA CTD PMID:19691856 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
G Npat nuclear protein, co-activator of histone transcription increases expression ISO Clorgyline results in increased expression of NPAT mRNA CTD PMID:19691856 NCBI chr 8:53,932,993...53,970,875
Ensembl chr 8:53,932,993...53,970,875
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Clorgyline results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO Clorgyline results in increased expression of NRIP1 mRNA CTD PMID:19691856 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nsrp1 nuclear speckle splicing regulatory protein 1 increases expression ISO Clorgyline results in increased expression of NSRP1 mRNA CTD PMID:19691856 NCBI chr10:61,880,807...61,914,471
Ensembl chr10:61,880,825...61,914,471
JBrowse link
G Nsun3 NOP2/Sun RNA methyltransferase 3 increases expression ISO Clorgyline results in increased expression of NSUN3 mRNA CTD PMID:19691856 NCBI chr11:37,490,832...37,575,607
Ensembl chr11:37,490,838...37,568,543
JBrowse link
G Nt5dc1 5'-nucleotidase domain containing 1 increases expression ISO Clorgyline results in increased expression of NT5DC1 mRNA CTD PMID:19691856 NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591
JBrowse link
G Nudcd1 NudC domain containing 1 increases expression ISO Clorgyline results in increased expression of NUDCD1 mRNA CTD PMID:19691856 NCBI chr 7:75,550,650...75,595,976
Ensembl chr 7:75,550,346...75,595,900
JBrowse link
G Odf2l outer dense fiber of sperm tails 2-like increases expression ISO Clorgyline results in increased expression of ODF2L mRNA CTD PMID:19691856 NCBI chr 2:234,036,049...234,072,751
Ensembl chr 2:234,033,652...234,072,747
JBrowse link
G Pcm1 pericentriolar material 1 increases expression ISO Clorgyline results in increased expression of PCM1 mRNA CTD PMID:19691856 NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091
JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 increases expression ISO Clorgyline results in increased expression of PCMTD1 mRNA CTD PMID:19691856 NCBI chr 5:12,284,711...12,355,680
Ensembl chr 5:12,284,711...12,354,899
JBrowse link
G Pdik1l PDLIM1 interacting kinase 1 like increases expression ISO Clorgyline results in increased expression of PDIK1L mRNA CTD PMID:19691856 NCBI chr 5:146,495,115...146,507,363
Ensembl chr 5:146,495,115...146,506,835
JBrowse link
G Phf14 PHD finger protein 14 increases expression ISO Clorgyline results in increased expression of PHF14 mRNA CTD PMID:19691856 NCBI chr 4:40,009,691...40,195,870
Ensembl chr 4:40,009,264...40,195,885
JBrowse link
G Phf3 PHD finger protein 3 increases expression ISO Clorgyline results in increased expression of PHF3 mRNA CTD PMID:19691856 NCBI chr 9:33,063,855...33,136,013
Ensembl chr 9:33,063,857...33,135,994
JBrowse link
G Phip pleckstrin homology domain interacting protein increases expression ISO Clorgyline results in increased expression of PHIP mRNA CTD PMID:19691856 NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha increases expression ISO Clorgyline results in increased expression of PIK3C2A mRNA CTD PMID:19691856 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
JBrowse link
G Polk DNA polymerase kappa increases expression ISO Clorgyline results in increased expression of POLK mRNA CTD PMID:19691856 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions ISO [[Clorgyline results in decreased activity of MAOA protein] co-treated with [Pargyline results in decreased activity of MAOB protein]] inhibits the reaction [resveratrol promotes the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]]; [[Clorgyline results in decreased activity of MAOA protein] co-treated with [Pargyline results in decreased activity of MAOB protein]] promotes the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein] CTD PMID:23499958 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 increases expression ISO Clorgyline results in increased expression of PREX2 mRNA CTD PMID:19691856 NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068
JBrowse link
G Prodh2 proline dehydrogenase 2 increases expression ISO Clorgyline results in increased expression of PRODH2 mRNA CTD PMID:19691856 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 increases expression ISO Clorgyline results in increased expression of PTPN22 mRNA CTD PMID:19691856 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO Clorgyline results in increased expression of RAD50 mRNA CTD PMID:19691856 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rad54b RAD54 homolog B increases expression ISO Clorgyline results in increased expression of RAD54B mRNA CTD PMID:19691856 NCBI chr 5:25,030,885...25,104,616
Ensembl chr 5:25,032,066...25,104,616
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression ISO Clorgyline results in increased expression of RAPGEF4 mRNA CTD PMID:19691856 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 increases expression ISO Clorgyline results in increased expression of RB1CC1 mRNA CTD PMID:19691856 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit increases expression ISO Clorgyline results in increased expression of REV3L mRNA CTD PMID:19691856 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099
JBrowse link
G Rgs5 regulator of G-protein signaling 5 increases expression ISO Clorgyline results in increased expression of RGS5 mRNA CTD PMID:19691856 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 increases expression ISO Clorgyline results in increased expression of RICTOR mRNA CTD PMID:19691856 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Samd9 sterile alpha motif domain containing 9 increases expression ISO Clorgyline results in increased expression of SAMD9 mRNA CTD PMID:19691856 NCBI chr 4:31,164,639...31,184,325
Ensembl chr 4:31,164,510...31,184,322
JBrowse link
G Scaf11 SR-related CTD-associated factor 11 increases expression ISO Clorgyline results in increased expression of SCAF11 mRNA CTD PMID:19691856 NCBI chr 7:127,571,678...127,623,915
Ensembl chr 7:127,574,463...127,624,101
JBrowse link
G Selenop selenoprotein P increases expression ISO Clorgyline results in increased expression of SELENOP mRNA CTD PMID:19691856 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Sema3c semaphorin 3C increases expression ISO Clorgyline results in increased expression of SEMA3C mRNA CTD PMID:19691856 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
JBrowse link
G Senp6 SUMO specific peptidase 6 increases expression ISO Clorgyline results in increased expression of SENP6 mRNA CTD PMID:19691856 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170
JBrowse link
G Senp7 SUMO specific peptidase 7 increases expression ISO Clorgyline results in increased expression of SENP7 mRNA CTD PMID:19691856 NCBI chr11:44,423,735...44,584,129
Ensembl chr11:44,423,735...44,564,711
JBrowse link
G Shoc2 SHOC2 leucine-rich repeat scaffold protein increases expression ISO Clorgyline results in increased expression of SHOC2 mRNA CTD PMID:19691856 NCBI chr 1:252,958,939...253,048,820
Ensembl chr 1:252,959,723...253,047,337
JBrowse link
G Slc4a5 solute carrier family 4 member 5 increases expression ISO Clorgyline results in increased expression of SLC4A5 mRNA CTD PMID:19691856 NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323
JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 increases expression ISO Clorgyline results in increased expression of SLITRK6 mRNA CTD PMID:19691856 NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393
JBrowse link
G Slk STE20-like kinase increases expression ISO Clorgyline results in increased expression of SLK mRNA CTD PMID:19691856 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530
JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 increases expression ISO Clorgyline results in increased expression of SMCHD1 mRNA CTD PMID:19691856 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Clorgyline results in increased expression of SOCS2 mRNA CTD PMID:19691856 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Stag2 stromal antigen 2 increases expression ISO Clorgyline results in increased expression of STAG2 mRNA CTD PMID:19691856 NCBI chr  X:120,974,687...121,105,677
Ensembl chr  X:120,974,857...121,105,677
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Steap2 STEAP2 metalloreductase increases expression ISO Clorgyline results in increased expression of STEAP2 mRNA CTD PMID:19691856 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
JBrowse link
G Stxbp4 syntaxin binding protein 4 increases expression ISO Clorgyline results in increased expression of STXBP4 mRNA CTD PMID:19691856 NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663
JBrowse link
G Tbc1d15 TBC1 domain family, member 15 increases expression ISO Clorgyline results in increased expression of TBC1D15 mRNA CTD PMID:19691856 NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175
JBrowse link
G Tbc1d8b TBC1 domain family member 8B increases expression ISO Clorgyline results in increased expression of TBC1D8B mRNA CTD PMID:19691856 NCBI chr  X:103,319,181...103,407,137
Ensembl chr  X:103,319,340...103,407,133
JBrowse link
G Tceal7 transcription elongation factor A like 7 increases expression ISO Clorgyline results in increased expression of TCEAL7 mRNA CTD PMID:19691856 NCBI chr  X:99,228,405...99,230,551
Ensembl chr  X:99,228,458...99,230,543
JBrowse link
G Tex9 testis expressed 9 increases expression ISO Clorgyline results in increased expression of TEX9 mRNA CTD PMID:19691856 NCBI chr 8:73,168,519...73,213,935
Ensembl chr 8:73,177,810...73,214,261
JBrowse link
G Thap2 THAP domain containing 2 increases expression ISO Clorgyline results in increased expression of THAP2 mRNA CTD PMID:19691856
G Tmed5 transmembrane p24 trafficking protein 5 increases expression ISO Clorgyline results in increased expression of TMED5 mRNA CTD PMID:19691856 NCBI chr14:1,607,895...1,619,028
Ensembl chr14:1,607,819...1,628,426
JBrowse link
G Tmem106b transmembrane protein 106B increases expression ISO Clorgyline results in increased expression of TMEM106B mRNA CTD PMID:19691856 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Tmf1 TATA element modulatory factor 1 increases expression ISO Clorgyline results in increased expression of TMF1 mRNA CTD PMID:19691856 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Clorgyline inhibits the reaction [Cisplatin results in increased secretion of TNF protein] CTD PMID:34560070 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trip11 thyroid hormone receptor interactor 11 increases expression ISO Clorgyline results in increased expression of TRIP11 mRNA CTD PMID:19691856 NCBI chr 6:120,995,242...121,067,693
Ensembl chr 6:120,998,733...121,067,781
JBrowse link
G Tut7 terminal uridylyl transferase 7 increases expression ISO Clorgyline results in increased expression of TUT7 mRNA CTD PMID:19691856 NCBI chr17:4,849,287...4,903,542
Ensembl chr17:4,849,283...4,903,169
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W increases expression ISO Clorgyline results in increased expression of UBE2W mRNA CTD PMID:19691856 NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965
JBrowse link
G Ublcp1 ubiquitin-like domain containing CTD phosphatase 1 increases expression ISO Clorgyline results in increased expression of UBLCP1 mRNA CTD PMID:19691856 NCBI chr10:28,945,692...28,961,103
Ensembl chr10:28,945,698...28,960,996
JBrowse link
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay increases expression ISO Clorgyline results in increased expression of UPF3B mRNA CTD PMID:19691856 NCBI chr  X:116,335,308...116,353,332
Ensembl chr  X:116,335,308...116,353,236
JBrowse link
G Utrn utrophin increases expression ISO Clorgyline results in increased expression of UTRN mRNA CTD PMID:22028826 NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 increases expression ISO Clorgyline results in increased expression of VCPIP1 mRNA CTD PMID:19691856 NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040
JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A increases expression ISO Clorgyline results in increased expression of VPS13A mRNA CTD PMID:19691856 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555
JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C increases expression ISO Clorgyline results in increased expression of VPS13C mRNA CTD PMID:19691856 NCBI chr 8:68,478,366...68,651,893
Ensembl chr 8:68,478,395...68,651,895
JBrowse link
G Vps37a VPS37A subunit of ESCRT-I increases expression ISO Clorgyline results in increased expression of VPS37A mRNA CTD PMID:19691856 NCBI chr16:51,736,170...51,775,384
Ensembl chr16:51,737,481...51,775,390
JBrowse link
G Wdr17 WD repeat domain 17 increases expression ISO Clorgyline results in increased expression of WDR17 mRNA CTD PMID:19691856 NCBI chr16:37,059,923...37,191,125
Ensembl chr16:37,059,895...37,191,122
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO Clorgyline results in increased expression of ZBTB1 mRNA CTD PMID:19691856 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO Clorgyline results in increased expression of ZBTB10 mRNA CTD PMID:19691856 NCBI chr 2:92,475,254...92,509,857
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zfp280c zinc finger protein 280C increases expression ISO Clorgyline results in increased expression of ZNF280C mRNA CTD PMID:19691856 NCBI chr  X:127,716,403...127,807,600
Ensembl chr  X:127,717,983...127,779,825
JBrowse link
G Zfp280d zinc finger protein 280D increases expression ISO Clorgyline results in increased expression of ZNF280D mRNA CTD PMID:19691856 NCBI chr 8:72,992,655...73,080,482
Ensembl chr 8:72,992,650...73,080,480
JBrowse link
G Zfp292 zinc finger protein 292 increases expression ISO Clorgyline results in increased expression of ZNF292 mRNA CTD PMID:19691856 NCBI chr 5:49,384,177...49,468,177
Ensembl chr 5:49,387,893...49,468,265
JBrowse link
G Zfp449 zinc finger protein 449 increases expression ISO Clorgyline results in increased expression of ZNF449 mRNA CTD PMID:19691856 NCBI chr  X:134,120,820...134,140,921
Ensembl chr  X:134,122,636...134,140,924
JBrowse link
G Zfp638 zinc finger protein 638 increases expression ISO Clorgyline results in increased expression of ZNF638 mRNA CTD PMID:19691856 NCBI chr 4:116,355,934...116,479,845
Ensembl chr 4:116,402,428...116,479,845
JBrowse link
G Zfp644 zinc finger protein 644 increases expression ISO Clorgyline results in increased expression of ZNF644 mRNA CTD PMID:19691856 NCBI chr14:3,105,002...3,179,955
Ensembl chr14:3,105,178...3,179,940
JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 increases expression ISO Clorgyline results in increased expression of ZFYVE16 mRNA CTD PMID:19691856 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      application 19737
        refrigerant 18086
          ammonia 17516
            organic amino compound 17516
              tertiary amino compound 8850
                clorgyline 160
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic molecule 19809
                              organic cyclic compound 19572
                                carbocyclic compound 18516
                                  benzenoid aromatic compound 17764
                                    benzenes 17567
                                      chlorobenzenes 13889
                                        dichlorobenzene 10995
                                          clorgyline 160
paths to the root