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ONTOLOGY REPORT - ANNOTATIONS


Term:clorgyline
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Accession:CHEBI:3763 term browser browse the term
Definition:An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.
Synonyms:exact_synonym: N-[3-(2,4-dichlorophenoxy)propyl]-N-methylprop-2-yn-1-amine
 related_synonym: Formula=C13H15Cl2NO;   InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3;   InChIKey=BTFHLQRNAMSNLC-UHFFFAOYSA-N;   M and B 9302;   M&B 9302;   N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-2-propynylamine;   N-methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine;   SMILES=CN(CCCOc1ccc(Cl)cc1Cl)CC#C;   clorgilina;   clorgiline;   clorgilinum
 xref: CAS:17780-72-2 "ChemIDplus";   CAS:17780-72-2 "KEGG COMPOUND";   CAS:17780-72-2 "NIST Chemistry WebBook";   DrugBank:DB04017;   KEGG:C11685;   KEGG:D03248;   LINCS:LSM-5808
 xref_mesh: MESH:D003010
 xref: MetaCyc:CPD-7656;   PDBeChem:MLG;   PMID:21079379 "Europe PMC";   PMID:22203607 "Europe PMC";   PMID:23546802 "Europe PMC";   PMID:5119769 "Europe PMC";   Reaxys:1976758 "Reaxys";   Wikipedia:Clorgiline


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clorgyline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca5 ATP binding cassette subfamily A member 5 JBrowse link 10 98,573,226 98,645,028 RGD:6480464
G Acadsb acyl-CoA dehydrogenase, short/branched chain JBrowse link 1 201,981,362 202,022,771 RGD:6480464
G Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 JBrowse link 11 73,078,966 73,193,496 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Akap11 A-kinase anchoring protein 11 JBrowse link 15 60,722,138 60,766,673 RGD:6480464
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:6480464
G Ankrd12 ankyrin repeat domain 12 JBrowse link 9 113,605,683 113,682,482 RGD:6480464
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 JBrowse link 14 48,726,033 48,922,809 RGD:6480464
G Arid4a AT-rich interaction domain 4A JBrowse link 6 93,461,713 93,532,901 RGD:6480464
G Atg4c autophagy related 4C, cysteine peptidase JBrowse link 5 117,861,517 117,932,116 RGD:6480464
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:6480464
G Azi2 5-azacytidine induced 2 JBrowse link 8 126,411,030 126,435,581 RGD:6480464
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 JBrowse link 11 84,919,055 84,931,160 RGD:6480464
G Baz2b bromodomain adjacent to zinc finger domain, 2B JBrowse link 3 45,968,845 46,286,915 RGD:6480464
G Bdp1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB JBrowse link 2 30,248,458 30,340,211 RGD:6480464
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 JBrowse link 14 73,738,137 73,792,935 RGD:6480464
G Brwd1 bromodomain and WD repeat domain containing 1 JBrowse link 11 36,338,080 36,430,473 RGD:6480464
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:6480464
G Cbln2 cerebellin 2 precursor JBrowse link 18 83,775,568 83,783,841 RGD:6480464
G Ccdc112 coiled-coil domain containing 112 JBrowse link 18 40,220,855 40,254,845 RGD:6480464
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:6480464
G Cenpc centromere protein C JBrowse link 14 23,611,909 23,670,314 RGD:6480464
G Cep135 centrosomal protein 135 JBrowse link 14 34,052,168 34,115,763 RGD:6480464
G Cep290 centrosomal protein 290 JBrowse link 7 40,217,269 40,306,327 RGD:6480464
G Cep350 centrosomal protein 350 JBrowse link 13 73,499,715 73,637,707 RGD:6480464
G Cep70 centrosomal protein 70 JBrowse link 8 107,495,326 107,548,274 RGD:6480464
G Cfh complement factor H JBrowse link 13 56,979,155 57,080,540 RGD:6480464
G Chd9 chromodomain helicase DNA binding protein 9 JBrowse link 19 17,364,969 17,517,757 RGD:6480464
G Chic1 cysteine-rich hydrophobic domain 1 JBrowse link X 74,205,649 74,250,613 RGD:6480464
G Chm CHM Rab escort protein JBrowse link X 84,666,900 84,821,775 RGD:6480464
G Clgn calmegin JBrowse link 19 24,545,257 24,578,527 RGD:6480464
G Clip1 CAP-GLY domain containing linker protein 1 JBrowse link 12 38,345,203 38,452,650 RGD:6480464
G Cntn3 contactin 3 JBrowse link 4 134,783,671 135,159,309 RGD:6480464
G Cobll1 cordon-bleu WH2 repeat protein-like 1 JBrowse link 3 51,137,104 51,298,956 RGD:6480464
G Cpd carboxypeptidase D JBrowse link 10 63,325,764 63,389,811 RGD:6480464
G Cpne9 copine family member 9 JBrowse link 4 145,238,011 145,262,444 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Dkkl1 dickkopf like acrosomal protein 1 JBrowse link 1 101,205,426 101,210,675 RGD:6480464
G Dmxl1 Dmx-like 1 JBrowse link 18 44,468,762 44,644,769 RGD:6480464
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 JBrowse link 3 67,538,289 67,578,308 RGD:6480464
G Dst dystonin JBrowse link 9 37,902,336 38,296,961 RGD:6480464
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 8 5,217,054 5,436,969 RGD:6480464
G Dync2li1 dynein cytoplasmic 2 light intermediate chain 1 JBrowse link 6 7,900,962 7,933,795 RGD:6480464
G Echdc1 ethylmalonyl-CoA decarboxylase 1 JBrowse link 1 30,874,410 30,921,117 RGD:6480464
G Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 JBrowse link 18 1,789,796 1,857,271 RGD:6480464
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Fzd3 frizzled class receptor 3 JBrowse link 15 48,601,259 48,670,257 RGD:6480464
G Gabpa GA binding protein transcription factor subunit alpha JBrowse link 11 24,293,845 24,322,822 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Gcc2 GRIP and coiled-coil domain containing 2 JBrowse link 20 27,832,960 27,879,764 RGD:6480464
G Gk glycerol kinase JBrowse link X 54,227,291 54,303,897 RGD:6480464
G Gnpda2 glucosamine-6-phosphate deaminase 2 JBrowse link 14 62,628,102 62,646,158 RGD:6480464
G Golga4 golgin A4 JBrowse link 8 127,171,221 127,248,938 RGD:6480464
G Golgb1 golgin B1 JBrowse link 11 66,761,646 66,819,115 RGD:6480464
G Hbb-b1 hemoglobin, beta adult major chain JBrowse link 1 168,945,531 168,953,023 RGD:6480464
G Hint3 histidine triad nucleotide binding protein 3 JBrowse link 1 29,413,425 29,423,288 RGD:6480464
G Ibtk inhibitor of Bruton tyrosine kinase JBrowse link 8 93,323,454 93,397,044 RGD:6480464
G Ift80 intraflagellar transport 80 JBrowse link 2 165,506,878 165,600,748 RGD:6480464
G Klhdc1 kelch domain containing 1 JBrowse link 6 91,532,380 91,584,112 RGD:6480464
G Klhl2 kelch-like family member 2 JBrowse link 16 26,755,246 26,852,134 RGD:6480464
G Ktn1 kinectin 1 JBrowse link 15 24,465,761 24,552,833 RGD:6480464
G Larp1b La ribonucleoprotein domain family, member 1B JBrowse link 2 127,845,034 127,876,793 RGD:6480464
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:6480464
G Lrat lecithin retinol acyltransferase JBrowse link 2 181,896,304 181,905,366 RGD:6480464
G Ltb lymphotoxin beta JBrowse link 20 5,184,631 5,186,476 RGD:6480464
G Manea mannosidase, endo-alpha JBrowse link 5 40,845,103 40,867,025 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Map9 microtubule-associated protein 9 JBrowse link 2 181,331,426 181,367,245 RGD:6480464
G Mbnl2 muscleblind-like splicing regulator 2 JBrowse link 15 105,640,097 105,797,933 RGD:6480464
G Mia2 MIA SH3 domain ER export factor 2 JBrowse link 6 80,188,721 80,286,918 RGD:6480464
G Mipol1 mirror-image polydactyly 1 JBrowse link 6 78,172,842 78,506,232 RGD:6480464
G Mob1b MOB kinase activator 1B JBrowse link 14 20,960,052 20,992,753 RGD:6480464
G Mon2 MON2 homolog, regulator of endosome-to-Golgi trafficking JBrowse link 7 66,717,470 66,794,041 RGD:6480464
G Mospd2 motile sperm domain containing 2 JBrowse link X 31,140,967 31,182,823 RGD:6480464
G Mpp7 membrane palmitoylated protein 7 JBrowse link 17 60,057,077 60,250,303 RGD:6480464
G Myo6 myosin VI JBrowse link 8 87,583,649 87,731,271 RGD:6480464
G Ndfip2 Nedd4 family interacting protein 2 JBrowse link 15 89,407,426 89,458,983 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nipbl NIPBL, cohesin loading factor JBrowse link 2 57,508,830 57,676,197 RGD:6480464
G Npat nuclear protein, co-activator of histone transcription JBrowse link 8 58,120,179 58,158,052 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:6480464
G Nsrp1 nuclear speckle splicing regulatory protein 1 JBrowse link 10 63,098,115 63,131,779 RGD:6480464
G Nsun3 NOP2/Sun RNA methyltransferase 3 JBrowse link 11 38,535,971 38,590,274 RGD:6480464
G Nt5dc1 5'-nucleotidase domain containing 1 JBrowse link 20 41,106,990 41,209,765 RGD:6480464
G Nudcd1 NudC domain containing 1 JBrowse link 7 83,302,778 83,348,534 RGD:6480464
G Odf2l outer dense fiber of sperm tails 2-like JBrowse link 2 250,995,018 251,032,908 RGD:6480464
G Pcm1 pericentriolar material 1 JBrowse link 16 54,040,721 54,137,675 RGD:6480464
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 JBrowse link 5 12,132,657 12,204,376 RGD:6480464
G Pdik1l PDLIM1 interacting kinase 1 like JBrowse link 5 152,494,963 152,507,693 RGD:6480464
G Phf14 PHD finger protein 14 JBrowse link 4 38,241,189 38,420,199 RGD:6480464
G Phf3 PHD finger protein 3 JBrowse link 9 37,073,514 37,144,027 RGD:6480464
G Phip pleckstrin homology domain interacting protein JBrowse link 8 90,387,339 90,483,964 RGD:6480464
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha JBrowse link 1 185,210,922 185,326,314 RGD:6480464
G Polk DNA polymerase kappa JBrowse link 2 27,305,718 27,364,906 RGD:6480464
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B JBrowse link 10 86,303,727 86,312,770 RGD:6480464
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 JBrowse link 5 7,622,668 7,941,715 RGD:6480464
G Prodh2 proline dehydrogenase 2 JBrowse link 1 88,955,125 88,968,501 RGD:6480464
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:6480464
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:6480464
G Rad54b RAD54 homolog B JBrowse link 5 25,140,531 25,214,469 RGD:6480464
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:6480464
G Rb1cc1 RB1-inducible coiled-coil 1 JBrowse link 5 13,033,918 13,097,369 RGD:6480464
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit JBrowse link 20 44,803,664 44,961,362 RGD:6480464
G Rgs5 regulator of G-protein signaling 5 JBrowse link 13 87,966,820 88,002,831 RGD:6480464
G Rictor RPTOR independent companion of MTOR, complex 2 JBrowse link 2 56,013,898 56,105,818 RGD:6480464
G Samd9 sterile alpha motif domain containing 9 JBrowse link 4 28,304,967 28,324,637 RGD:6480464
G Scaf11 SR-related CTD-associated factor 11 JBrowse link 7 137,804,019 137,856,337 RGD:6480464
G Selenop selenoprotein P JBrowse link 2 53,105,912 53,116,198 RGD:6480464
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:6480464
G Senp6 SUMO specific peptidase 6 JBrowse link 8 87,486,050 87,568,088 RGD:6480464
G Senp7 SUMO specific peptidase 7 JBrowse link 11 46,880,928 47,047,052 RGD:6480464
G Shoc2 SHOC2 leucine-rich repeat scaffold protein JBrowse link 1 274,700,621 274,751,195 RGD:6480464
G Slc4a5 solute carrier family 4 member 5 JBrowse link 4 114,918,488 115,002,290 RGD:6480464
G Slitrk6 SLIT and NTRK-like family, member 6 JBrowse link 15 95,507,632 95,514,259 RGD:6480464
G Slk STE20-like kinase JBrowse link 1 267,359,761 267,415,735 RGD:6480464
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:6480464
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:6480464
G Stag2 stromal antigen 2 JBrowse link X 128,493,603 128,624,418 RGD:6480464
G Steap2 STEAP2 metalloreductase JBrowse link 4 25,506,604 25,527,088 RGD:6480464
G Stxbp4 syntaxin binding protein 4 JBrowse link 10 78,005,745 78,168,641 RGD:6480464
G Tbc1d15 TBC1 domain family, member 15 JBrowse link 7 58,164,190 58,219,804 RGD:6480464
G Tbc1d8b TBC1 domain family member 8B JBrowse link X 110,894,831 110,983,269 RGD:6480464
G Tceal7 transcription elongation factor A like 7 JBrowse link X 106,774,954 106,777,072 RGD:6480464
G Tex9 testis expressed 9 JBrowse link 8 79,083,449 79,119,621 RGD:6480464
G Thap2 THAP domain containing 2 JBrowse link 7 58,350,744 58,365,812 RGD:6480464
G Tmed5 transmembrane p24 trafficking protein 5 JBrowse link 14 2,613,318 2,624,773 RGD:6480464
G Tmem106b transmembrane protein 106B JBrowse link 4 39,517,679 39,534,491 RGD:6480464
G Tmf1 TATA element modulatory factor 1 JBrowse link 4 129,521,986 129,546,024 RGD:6480464
G Trip11 thyroid hormone receptor interactor 11 JBrowse link 6 125,741,520 125,812,926 RGD:6480464
G Tut7 terminal uridylyl transferase 7 JBrowse link 17 5,225,854 5,279,674 RGD:6480464
G Ube2w ubiquitin-conjugating enzyme E2W JBrowse link 5 29,798,845 29,812,777 RGD:6480464
G Ublcp1 ubiquitin-like domain containing CTD phosphatase 1 JBrowse link 10 30,103,607 30,118,945 RGD:6480464
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay JBrowse link X 123,713,327 123,731,431 RGD:6480464
G Utrn utrophin JBrowse link 1 6,451,809 6,970,040 RGD:6480464
G Vcpip1 valosin containing protein interacting protein 1 JBrowse link 5 9,231,180 9,257,821 RGD:6480464
G Vps13a vacuolar protein sorting 13 homolog A JBrowse link 1 235,352,513 235,813,597 RGD:6480464
G Vps13c vacuolar protein sorting 13 homolog C JBrowse link 8 73,682,814 73,843,290 RGD:6480464
G Vps37a VPS37A subunit of ESCRT-I JBrowse link 16 54,860,811 54,899,410 RGD:6480464
G Wdr17 WD repeat domain 17 JBrowse link 16 39,810,285 39,938,953 RGD:6480464
G Zbtb1 zinc finger and BTB domain containing 1 JBrowse link 6 99,401,775 99,425,739 RGD:6480464
G Zbtb10 zinc finger and BTB domain containing 10 JBrowse link 2 94,692,939 94,730,976 RGD:6480464
G Zfp280c zinc finger protein 280C JBrowse link X 135,371,696 135,434,204 RGD:6480464
G Zfp280d zinc finger protein 280D JBrowse link 8 78,858,561 78,949,447 RGD:6480464
G Zfp292 zinc finger protein 292 JBrowse link 5 50,282,084 50,362,344 RGD:6480464
G Zfp300 zinc finger protein 300 JBrowse link X 893,915 912,840 RGD:6480464
G Zfp40 zinc finger protein 40 JBrowse link 1 62,555,186 62,577,750 RGD:6480464
G Zfp449 zinc finger protein 449 JBrowse link X 73,390,885 73,413,939 RGD:6480464
G Zfp638 zinc finger protein 638 JBrowse link 4 115,555,185 115,690,272 RGD:6480464
G Zfp644 zinc finger protein 644 JBrowse link 14 4,125,368 4,200,332 RGD:6480464
G Zfyve16 zinc finger FYVE-type containing 16 JBrowse link 2 22,060,879 22,105,822 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19614
    role 19557
      application 19155
        refrigerant 16861
          ammonia 16562
            organic amino compound 16561
              tertiary amino compound 8526
                clorgyline 155
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    p-block element atom 19489
                      carbon group element atom 19362
                        carbon atom 19354
                          organic molecular entity 19354
                            organic molecule 19272
                              organic cyclic compound 19061
                                carbocyclic compound 17475
                                  benzenoid aromatic compound 16965
                                    benzenes 16649
                                      chlorobenzenes 12529
                                        dichlorobenzene 9559
                                          clorgyline 155
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.