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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nitrogen mustard
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Accession:CHEBI:37598 term browser browse the term
Definition:Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Synonyms:related_synonym: nitrogen mustard compound;   nitrogen mustard compounds;   nitrogen mustards
 alt_id: MESH:D009588
 xref_mesh: MESH:D009588
 xref: Wikipedia:Nitrogen_mustard


show annotations for term's descendants           Sort by:
nitrogen mustard term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression 		ISO caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in decreased expression of AHR protein] CTD PMID:17204746 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Alb albumin increases alkylation ISO Nitrogen Mustard Compounds results in increased alkylation of ALB protein CTD PMID:18269793 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression
multiple interactions 		ISO Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA
Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA] 		CTD PMID:10344722 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763 		JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions
increases expression
decreases expression 		ISO Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA2 mRNA]
Nitrogen Mustard Compounds results in increased expression of BRCA2 mRNA 		CTD PMID:10344722 PMID:27342729 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194 		JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions 		ISO Nitrogen Mustard Compounds results in decreased expression of CDH2 mRNA; Nitrogen Mustard Compounds results in decreased expression of CDH2 protein
Plant Extracts inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of CDH2 mRNA]; Plant Extracts inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of CDH2 protein] 		CTD PMID:18572855 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Dhfr dihydrofolate reductase decreases response to substance ISO DHFR protein polymorphism results in decreased susceptibility to Nitrogen Mustard Compounds CTD PMID:12872145 NCBI chr 2:25,320,895...25,346,004 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO Nitrogen Mustard Compounds results in decreased expression of ERBB2 mRNA CTD PMID:16417271 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Fancd2 FA complementation group D2 increases expression ISO Nitrogen Mustard Compounds results in increased expression of FANCD2 mRNA; Nitrogen Mustard Compounds results in increased expression of FANCD2 protein CTD PMID:27342729 NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases response to substance EXP GSTA3 protein results in decreased susceptibility to Nitrogen Mustard Compounds CTD PMID:9414483 PMID:12872145 NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression 		ISO MGMT protein affects the reaction [Nitrogen Mustard Compounds results in increased expression of H2AX protein]; Nitrogen Mustard Compounds results in decreased expression of and results in increased phosphorylation of H2AX protein
Nitrogen Mustard Compounds results in increased expression of H2AX mRNA; Nitrogen Mustard Compounds results in increased expression of H2AX protein 		CTD PMID:27342729 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects response to substance ISO IGF1R protein affects the susceptibility to Nitrogen Mustard Compounds CTD PMID:15499378 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions
decreases expression 		ISO MGMT protein affects the reaction [Nitrogen Mustard Compounds results in increased expression of H2AX protein]; MGMT protein affects the reaction [Nitrogen Mustard Compounds results in increased expression of SPRTN protein]
Nitrogen Mustard Compounds results in decreased expression of MGMT mRNA 		CTD PMID:27342729 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions 		ISO Nitrogen Mustard Compounds results in increased expression of NFE2L2 protein
caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in increased expression of NFE2L2 protein] 		CTD PMID:17204746 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation ISO Nitrogen Mustard Compounds results in increased degradation of NFKBIA protein CTD PMID:17204746 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 multiple interactions
increases phosphorylation 		ISO caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of RPS6KA2 protein] CTD PMID:17204746 NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338 		JBrowse link
G Sprtn SprT-like N-terminal domain multiple interactions
increases expression 		ISO MGMT protein affects the reaction [Nitrogen Mustard Compounds results in increased expression of SPRTN protein]
Nitrogen Mustard Compounds results in increased expression of SPRTN mRNA; Nitrogen Mustard Compounds results in increased expression of SPRTN protein 		CTD PMID:27342729 NCBI chr19:52,857,612...52,864,864
Ensembl chr19:69,754,980...69,762,237 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases phosphorylation 		ISO caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of TP53 protein] CTD PMID:17204746 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vim vimentin decreases expression ISO Nitrogen Mustard Compounds results in decreased expression of VIM mRNA; Nitrogen Mustard Compounds results in decreased expression of VIM protein CTD PMID:17192600 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Nitrogen Mustard Compounds CTD PMID:10717383 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
4-hydroperoxycyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO perfosfamide results in increased expression of ABL1 mRNA CTD PMID:19429390 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846 		JBrowse link
G Actb actin, beta decreases expression ISO perfosfamide results in decreased expression of ACTB mRNA CTD PMID:19429390 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Agt angiotensinogen decreases response to substance ISO AGT protein results in decreased susceptibility to perfosfamide CTD PMID:11034089 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
increases response to substance 		ISO Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of AIFM1 protein]; perfosfamide results in increased expression of and results in increased localization of AIFM1 protein
AIFM1 results in increased susceptibility to perfosfamide 		CTD PMID:18034189 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 affects response to substance ISO AKR1B10 protein affects the susceptibility to perfosfamide CTD PMID:18473730 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases response to substance ISO ALDH1A1 protein results in decreased susceptibility to perfosfamide CTD PMID:8662658 PMID:16614850 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases response to substance ISO ALDH1A2 protein results in decreased susceptibility to perfosfamide CTD PMID:22079344 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects response to substance ISO ALDH1B1 protein affects the susceptibility to perfosfamide CTD PMID:18473730 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases response to substance ISO ALDH2 protein results in decreased susceptibility to perfosfamide CTD PMID:22079344 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases response to substance ISO ALDH3A1 protein results in decreased susceptibility to perfosfamide CTD PMID:16614850 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression EXP perfosfamide results in decreased expression of APEX1 mRNA CTD PMID:11754170 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects folding
increases expression 		ISO Acetylcysteine inhibits the reaction [perfosfamide affects the folding of BAX protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of BAX]; perfosfamide results in increased expression of and results in increased localization of BAX
perfosfamide results in increased expression of BAX protein 		CTD PMID:16488414 PMID:18034189 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO perfosfamide results in increased expression of BBC3 mRNA CTD PMID:17068108 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression ISO perfosfamide results in decreased expression of BMPR1B mRNA CTD PMID:19429390 NCBI chr 2:233,211,525...233,544,344
Ensembl chr 2:233,211,525...233,544,311 		JBrowse link
G C1d C1D nuclear receptor corepressor increases expression ISO perfosfamide results in increased expression of C1D mRNA CTD PMID:19429390 NCBI chr14:95,862,550...95,874,796
Ensembl chr14:95,861,978...95,874,796 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions 		ISO perfosfamide results in increased activity of CASP3
perfosfamide promotes the reaction [TNF results in increased activity of CASP3 protein] 		CTD PMID:16488414 PMID:17434952 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 increases activity ISO perfosfamide results in increased activity of CASP9 protein CTD PMID:16488414 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO perfosfamide results in increased expression of CDKN1A
perfosfamide results in increased expression of CDKN1A mRNA; perfosfamide results in increased expression of CDKN1A protein 		CTD PMID:17068108 PMID:18034189 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO perfosfamide results in decreased expression of CXCL9 mRNA CTD PMID:19429390 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO perfosfamide results in increased expression of E2F1 mRNA CTD PMID:19429390 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563 		JBrowse link
G Egr1 early growth response 1 decreases expression ISO perfosfamide results in decreased expression of EGR1 mRNA CTD PMID:19429390 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Endog endonuclease G increases response to substance
multiple interactions 		ISO ENDOG results in increased susceptibility to perfosfamide
Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of ENDOG protein]; perfosfamide results in increased expression of and results in increased localization of ENDOG protein 		CTD PMID:18034189 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573 		JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO perfosfamide results in increased expression of EPAS1 protein CTD PMID:23251655 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729 		JBrowse link
G Epha6 Eph receptor A6 decreases expression ISO perfosfamide results in decreased expression of EPHA6 mRNA CTD PMID:19429390 NCBI chr11:39,757,501...40,708,901
Ensembl chr11:53,226,954...54,166,987 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO perfosfamide results in decreased expression of EYA1 mRNA CTD PMID:19429390 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614 		JBrowse link
G Faslg Fas ligand increases expression ISO perfosfamide results in increased expression of FASLG mRNA; perfosfamide results in increased expression of FASLG protein CTD PMID:14760101 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Foxf1 forkhead box F1 affects expression ISO perfosfamide affects the expression of FOXF1 mRNA CTD PMID:19429390 NCBI chr19:66,062,635...66,066,427
Ensembl chr19:66,062,369...66,066,428 		JBrowse link
G Gjc1 gap junction protein, gamma 1 increases expression ISO perfosfamide results in increased expression of GJC1 mRNA CTD PMID:19429390 NCBI chr10:87,758,192...87,785,443
Ensembl chr10:88,249,489...88,285,853 		JBrowse link
G Gli2 GLI family zinc finger 2 decreases expression ISO perfosfamide results in decreased expression of GLI2 mRNA CTD PMID:19429390 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO perfosfamide results in increased expression of HES1 mRNA CTD PMID:19429390 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO perfosfamide results in increased expression of HIF1A mRNA; perfosfamide results in increased expression of HIF1A protein CTD PMID:19429390 PMID:23251655 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hoxa11 homeobox A11 decreases expression ISO perfosfamide results in decreased expression of HOXA11 mRNA CTD PMID:19429390 NCBI chr 4:82,673,139...82,676,801
Ensembl chr 4:82,673,140...82,676,844 		JBrowse link
G Hoxa13 homeo box A13 increases expression ISO perfosfamide results in increased expression of HOXA13 mRNA CTD PMID:19429390 NCBI chr 4:82,689,566...82,691,701
Ensembl chr 4:82,689,566...82,691,701 		JBrowse link
G Hoxd10 homeo box D10 increases expression ISO perfosfamide results in increased expression of HOXD10 mRNA CTD PMID:19429390 NCBI chr 3:80,001,947...80,005,156
Ensembl chr 3:80,001,689...80,005,156 		JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression ISO perfosfamide results in decreased expression of HRAS mRNA CTD PMID:19429390 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Kl Klotho decreases expression ISO perfosfamide results in decreased expression of KL mRNA CTD PMID:19429390 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015 		JBrowse link
G Lig3 DNA ligase 3 decreases expression EXP perfosfamide results in decreased expression of LIG3 mRNA CTD PMID:11754170 NCBI chr10:68,215,371...68,238,705
Ensembl chr10:68,215,407...68,238,704 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO perfosfamide results in increased expression of MDM2 CTD PMID:18034189 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression EXP perfosfamide results in decreased expression of MGMT mRNA CTD PMID:11754170 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482 		JBrowse link
G Mlh1 mutL homolog 1 decreases expression EXP perfosfamide results in decreased expression of MLH1 mRNA CTD PMID:11754170 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase decreases expression EXP perfosfamide results in decreased expression of MPG mRNA CTD PMID:11754170 NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease decreases expression EXP perfosfamide results in decreased expression of MRE11A mRNA CTD PMID:11754170 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904 		JBrowse link
G Myo1b myosin Ib increases expression ISO perfosfamide results in increased expression of MYO1B mRNA CTD PMID:19429390 NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328 		JBrowse link
G Myog myogenin increases expression ISO perfosfamide results in increased expression of MYOG mRNA CTD PMID:19429390 NCBI chr13:48,297,476...48,300,065
Ensembl chr13:48,297,235...48,300,065 		JBrowse link
G Ndn necdin, MAGE family member increases expression ISO perfosfamide results in increased expression of NDN mRNA CTD PMID:19429390 NCBI chr 1:125,261,059...125,262,658
Ensembl chr 1:125,260,997...125,262,785 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO perfosfamide results in decreased expression of ODC1 mRNA CTD PMID:19429390 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 decreases expression ISO perfosfamide results in decreased expression of PEA15 mRNA CTD PMID:19429390 NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO perfosfamide results in increased expression of PMAIP1 mRNA CTD PMID:17068108 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component decreases expression EXP perfosfamide results in decreased expression of PMS1 mRNA CTD PMID:11754170 NCBI chr 9:55,721,393...55,832,225
Ensembl chr 9:55,745,374...55,832,221 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component decreases expression EXP perfosfamide results in decreased expression of PMS2 mRNA CTD PMID:11754170 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Polb DNA polymerase beta decreases expression EXP perfosfamide results in decreased expression of POLB mRNA CTD PMID:11754170 NCBI chr16:76,081,903...76,105,174
Ensembl chr16:76,081,864...76,108,180 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit decreases expression ISO perfosfamide results in decreased expression of POLD1 mRNA CTD PMID:19429390 NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982 		JBrowse link
G Rad21 RAD21 cohesin complex component decreases expression ISO perfosfamide results in decreased expression of RAD21 mRNA CTD PMID:19429390 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657 		JBrowse link
G Rad50 RAD50 double strand break repair protein decreases expression EXP perfosfamide results in decreased expression of RAD50 mRNA CTD PMID:11754170 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rad51 RAD51 recombinase decreases expression EXP perfosfamide results in decreased expression of RAD51 mRNA CTD PMID:11754170 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Sdf4 stromal cell derived factor 4 decreases expression ISO perfosfamide results in decreased expression of SDF4 mRNA CTD PMID:19429390 NCBI chr 5:171,868,591...171,885,827
Ensembl chr 5:171,868,563...171,888,884 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression ISO perfosfamide results in decreased expression of SFRP2 mRNA CTD PMID:19429390 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Slc30a4 solute carrier family 30 member 4 decreases expression ISO perfosfamide results in decreased expression of SLC30A4 mRNA CTD PMID:19429390 NCBI chr 3:130,206,852...130,228,888
Ensembl chr 3:130,206,852...130,228,888 		JBrowse link
G Smad1 SMAD family member 1 decreases expression ISO perfosfamide results in decreased expression of SMAD1 mRNA CTD PMID:19429390 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member affects response to substance ISO TAP1 protein affects the susceptibility to perfosfamide CTD PMID:18473730 NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810 		JBrowse link
G Tcf12 transcription factor 12 increases expression ISO perfosfamide results in increased expression of TCF12 mRNA CTD PMID:19429390 NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:81,373,321...81,679,922 		JBrowse link
G Terc telomerase RNA component decreases expression ISO perfosfamide results in decreased expression of TERC mRNA CTD PMID:24571982 NCBI chr 2:114,744,148...114,744,535 JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO perfosfamide results in decreased expression of TERT mRNA CTD PMID:24571982 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO perfosfamide promotes the reaction [TNF results in increased activity of CASP3 protein] CTD PMID:16488414 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		ISO Acetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53]
perfosfamide results in increased expression of and results in increased phosphorylation of and results in increased activity of TRP53 protein 		CTD PMID:17068108 PMID:18034189 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Trim27 tripartite motif-containing 27 decreases expression ISO perfosfamide results in decreased expression of TRIM27 mRNA CTD PMID:19429390 NCBI chr17:48,233,999...48,246,348
Ensembl chr17:48,234,002...48,246,348 		JBrowse link
G Ttf1 transcription termination factor 1 decreases expression ISO perfosfamide results in decreased expression of TTF1 mRNA CTD PMID:19429390 NCBI chr 3:32,782,544...32,807,202
Ensembl chr 3:32,782,308...32,807,201 		JBrowse link
G Ubb ubiquitin B decreases expression ISO perfosfamide results in decreased expression of UBB mRNA CTD PMID:19429390 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,727,701...47,750,335 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO perfosfamide results in increased expression of VEGFA mRNA CTD PMID:19429390 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin decreases expression ISO perfosfamide results in decreased expression of VIM mRNA CTD PMID:19429390 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Wnt11 Wnt family member 11 increases expression ISO perfosfamide results in increased expression of WNT11 mRNA CTD PMID:19429390 NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression EXP perfosfamide results in decreased expression of XRCC1 mRNA CTD PMID:11754170 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 decreases expression EXP perfosfamide results in decreased expression of XRCC5 mRNA CTD PMID:11754170 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta decreases expression ISO perfosfamide results in decreased expression of YWHAZ mRNA CTD PMID:19429390 NCBI chr 7:69,826,404...69,848,702
Ensembl chr 7:69,826,404...69,849,007 		JBrowse link
4-hydroxycyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of ALOX5 mRNA CTD PMID:25833159 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126 		JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of BDKRB2 mRNA CTD PMID:25833159 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G Cd40 CD40 molecule multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of CD40 mRNA CTD PMID:25833159 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases chemical synthesis ISO CYP2B6 protein results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:24819615 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:30500380 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:30500380 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of IL1R1 mRNA CTD PMID:25833159 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of IL2RG mRNA CTD PMID:25833159 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:70,435,343...70,439,161 		JBrowse link
G Klk15 kallikrein-related peptidase 15 multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of KLK15 mRNA CTD PMID:25833159 NCBI chr 1:94,699,422...94,706,626
Ensembl chr 1:103,834,215...103,843,321 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of MAPK14 mRNA CTD PMID:25833159 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
Aldophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions
increases oxidation 		ISO [ALDH1A1 protein co-treated with NAD] results in increased oxidation of aldophosphamide
ALDH1A1 results in increased oxidation of aldophosphamide 		CTD PMID:8662658 PMID:10856427 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO [ALDH3A1 protein co-treated with NAD] results in increased oxidation of aldophosphamide; [ALDH3A1 protein co-treated with NADP] results in increased oxidation of aldophosphamide CTD PMID:10856427 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151 		JBrowse link
chlorambucil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Chlorambucil results in increased expression of ABCB1 protein CTD PMID:15239124 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects export
multiple interactions
increases response to substance
decreases response to substance 		ISO ABCC1 protein affects the export of Chlorambucil analog
buthionine sulfoximine ethyl ester promotes the reaction [ABCC1 protein results in increased susceptibility to Chlorambucil]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Chlorambucil] 		CTD PMID:10900222 PMID:11115505 PMID:12504668 PMID:14569069 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions 		ISO ABCC2 protein affects the export of Chlorambucil analog
ABCC2 protein promotes the reaction [GSTA1 protein results in decreased susceptibility to Chlorambucil] 		CTD PMID:14569069 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO Chlorambucil results in decreased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO Chlorambucil results in decreased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Asf1a anti-silencing function 1A histone chaperone decreases expression ISO Chlorambucil results in decreased expression of ASF1A mRNA CTD PMID:26198647 NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639 		JBrowse link
G Aurka aurora kinase A increases expression ISO Chlorambucil results in increased expression of AURKA protein CTD PMID:22025197 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Chlorambucil results in decreased expression of AURKB protein CTD PMID:22025197 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Chlorambucil results in increased expression of BAX protein CTD PMID:11699414 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Chlorambucil results in increased expression of BBC3 mRNA CTD PMID:17476690 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO Chlorambucil results in decreased expression of BCL2 mRNA; Chlorambucil results in decreased expression of BCL2 protein
IL4 protein inhibits the reaction [Chlorambucil results in decreased expression of BCL2 protein] 		CTD PMID:8822937 PMID:11699414 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bik BCL2-interacting killer increases expression ISO Chlorambucil results in increased expression of BIK mRNA CTD PMID:26198647 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance ISO BIRC2 protein results in decreased susceptibility to Chlorambucil CTD PMID:10815900 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects expression
decreases expression 		ISO Chlorambucil affects the expression of BIRC5 mRNA
Chlorambucil results in decreased expression of BIRC5 protein 		CTD PMID:17476690 PMID:22025197 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bmp5 bone morphogenetic protein 5 increases mutagenesis ISO Chlorambucil results in increased mutagenesis of BMP5 gene CTD PMID:10517996 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189 		JBrowse link
G Casp3 caspase 3 increases activity ISO Chlorambucil results in increased activity of CASP3 protein CTD PMID:11675354 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 increases activity ISO Chlorambucil results in increased activity of CASP8 protein CTD PMID:11675354 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Chlorambucil promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] CTD PMID:36416909 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cd59b CD59b molecule decreases lipidation EXP Chlorambucil results in decreased lipidation of CD59 protein CTD PMID:27931811 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Cda cytidine deaminase decreases response to substance ISO CDA protein results in decreased susceptibility to Chlorambucil CTD PMID:10830723 NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO Chlorambucil analog results in increased phosphorylation of and results in decreased activity of CDK1 protein CTD PMID:16861886 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Chlorambucil results in increased expression of CDKN1A protein CTD PMID:16039525 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Dhfr dihydrofolate reductase decreases response to substance ISO DHFR protein polymorphism results in decreased susceptibility to Chlorambucil CTD PMID:12872145 NCBI chr 2:25,320,895...25,346,004 JBrowse link
G Ednrb endothelin receptor type B increases mutagenesis ISO Chlorambucil results in increased mutagenesis of EDNRB gene CTD PMID:10517996 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Fancc FA complementation group C increases response to substance ISO FANCC protein results in increased susceptibility to Chlorambucil CTD PMID:16243825 NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096 		JBrowse link
G Fancg FA complementation group G increases response to substance ISO FANCG protein results in increased susceptibility to Chlorambucil CTD PMID:16243825 NCBI chr 5:62,027,494...62,037,202
Ensembl chr 5:62,027,500...62,035,787 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Chlorambucil results in increased expression of FAS mRNA CTD PMID:11675354 PMID:17476690 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Fbxo30 F-box protein 30 decreases expression ISO Chlorambucil results in decreased expression of FBXO30 mRNA CTD PMID:26198647 NCBI chr 1:7,475,636...7,491,719
Ensembl chr 1:7,475,575...7,493,199 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Chlorambucil CTD PMID:10900222 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Chlorambucil CTD PMID:10900222 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity
decreases response to substance
multiple interactions 		ISO Chlorambucil analog results in decreased activity of GSTA1 protein
GSTA1 protein results in decreased susceptibility to Chlorambucil
ABCC2 protein promotes the reaction [GSTA1 protein results in decreased susceptibility to Chlorambucil]; GSTA1 protein affects the metabolism of [Chlorambucil co-treated with Glutathione] 		CTD PMID:11115505 PMID:14569069 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases response to substance EXP GSTA3 protein results in decreased susceptibility to Chlorambucil CTD PMID:8044793 PMID:8860835 PMID:10830723 PMID:12872145 NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases response to substance EXP GSTA5 protein results in decreased susceptibility to Chlorambucil CTD PMID:12076520 NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases response to substance ISO GSTM1 protein results in decreased susceptibility to Chlorambucil CTD PMID:15044619 PMID:20067466 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects binding
increases metabolic processing
decreases response to substance
affects response to substance
multiple interactions 		ISO Chlorambucil binds to GSTP1 protein
GSTP1 protein results in increased metabolism of Chlorambucil
GSTP1 protein results in decreased susceptibility to Chlorambucil
GSTP1 gene affects the susceptibility to Chlorambucil
GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Chlorambucil] 		CTD PMID:10900222 PMID:11071881 PMID:18511072 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Chlorambucil analog results in increased phosphorylation of H2AX protein; Chlorambucil results in increased phosphorylation of H2AX protein CTD PMID:16861886 PMID:32482060 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein]; IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53]; IL4 protein inhibits the reaction [Chlorambucil results in decreased expression of BCL2 protein] CTD PMID:8822937 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil; Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil] CTD PMID:19608619 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Chlorambucil results in increased expression of LIF mRNA CTD PMID:26198647 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Chlorambucil results in increased expression of MDM2 mRNA CTD PMID:17476690 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
affects expression
increases expression 		ISO [Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein; IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of MYC protein]
Chlorambucil affects the expression of MYC mRNA
Chlorambucil results in increased expression of MYC protein 		CTD PMID:8822937 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myo5a myosin VA increases mutagenesis ISO Chlorambucil results in increased mutagenesis of MYO5A gene CTD PMID:10517996 NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects response to substance
increases response to substance 		ISO [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil; Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil]
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Chlorambucil
Buthionine Sulfoximine affects the reaction [[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Chlorambucil]; Buthionine Sulfoximine inhibits the reaction [NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Chlorambucil]]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Chlorambucil]
NFE2L2 gene mutant form results in increased susceptibility to Chlorambucil 		CTD PMID:19303893 PMID:19608619 PMID:20932822 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression ISO Chlorambucil affects the expression of PDK4 mRNA CTD PMID:32870474 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis
multiple interactions 		EXP Chlorambucil results in increased mutagenesis of PIGA
Chlorambucil results in increased mutagenesis of and results in decreased activity of PIGA protein 		CTD PMID:22923490 PMID:27931811 NCBI chr  X:33,672,832...33,687,747
Ensembl chr  X:33,674,923...33,687,636 		JBrowse link
G Rad51 RAD51 recombinase increases expression ISO Chlorambucil results in increased expression of RAD51 protein CTD PMID:10473103 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G RT1-Ha RT1 class II, locus Ha affects expression ISO Chlorambucil affects the expression of HLA-DPA1 mRNA CTD PMID:25811541 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141 		JBrowse link
G Sfn stratifin increases expression ISO Chlorambucil results in increased expression of SFN mRNA CTD PMID:18092340 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b affects expression ISO Chlorambucil affects the expression of TNFRSF10A mRNA CTD PMID:14614459 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
multiple interactions 		ISO Chlorambucil results in increased expression of TP53; Chlorambucil results in increased expression of TP53 protein
Chlorambucil affects the activity of TP53 protein
[Theophylline co-treated with Chlorambucil] results in increased expression of TP53; IL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53] 		CTD PMID:8822937 PMID:18092340 PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP Chlorambucil results in decreased activity of TXNRD1 protein CTD PMID:16085187 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 increases mutagenesis ISO Chlorambucil results in increased mutagenesis of TYRP1 gene CTD PMID:10517996 NCBI chr 5:100,327,111...100,345,657
Ensembl chr 5:100,327,125...100,345,657 		JBrowse link
cyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
increases expression 		ISO
EXP 		[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]
Cyclophosphamide results in decreased expression of ABCB1 mRNA; Cyclophosphamide results in decreased expression of ABCB1A mRNA 		CTD PMID:12576456 PMID:20041327 PMID:20623750 PMID:30563925 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases response to substance 		ISO ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
ABCC1 protein results in decreased susceptibility to Cyclophosphamide 		CTD PMID:11778547 PMID:12576456 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase increases expression ISO Cyclophosphamide results in increased expression of ABHD3 mRNA CTD PMID:21527772 NCBI chr18:1,996,010...2,051,311
Ensembl chr18:1,993,525...2,075,492 		JBrowse link
G Abi2 abl-interactor 2 decreases expression EXP Cyclophosphamide results in decreased expression of ABI2 mRNA CTD PMID:27466211 NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597 		JBrowse link
G Ace angiotensin I converting enzyme decreases expression EXP Cyclophosphamide results in decreased expression of ACE mRNA CTD PMID:27281708 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Cyclophosphamide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity
increases expression 		EXP coenzyme Q10 inhibits the reaction [Cyclophosphamide results in increased activity of ACHE protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of ACHE protein] CTD PMID:37419146 PMID:39209270 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression EXP Cyclophosphamide results in increased expression of ACKR3 mRNA CTD PMID:20032115 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214 		JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression ISO Cyclophosphamide results in increased expression of ACOD1 mRNA CTD PMID:15331540 NCBI chr15:86,286,531...86,295,803
Ensembl chr15:86,286,579...86,295,687 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of ACSL4 protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of ACSL4 protein] 		CTD PMID:37690746 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:110,739,648...110,803,261 		JBrowse link
G Actb actin, beta decreases expression
affects expression 		ISO
EXP 		Cyclophosphamide results in decreased expression of ACTB mRNA
Cyclophosphamide affects the expression of ACTB mRNA 		CTD PMID:10859244 PMID:12167460 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Adam24 ADAM metallopeptidase domain 24 decreases expression EXP Cyclophosphamide results in decreased expression of ADAM24 mRNA CTD PMID:27281708 NCBI chr16:51,578,278...51,584,265
Ensembl chr16:58,281,748...58,287,735 		JBrowse link
G Adam4 a disintegrin and metalloprotease domain 4 decreases expression EXP Cyclophosphamide results in decreased expression of ADAM4 mRNA CTD PMID:27281708 NCBI chr 6:101,123,284...101,125,730 JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression EXP Cyclophosphamide results in increased expression of ADAMTS9 mRNA CTD PMID:27281708 NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 affects expression
increases expression 		EXP Cyclophosphamide affects the expression of ADCYAP1 mRNA
Cyclophosphamide results in increased expression of ADCYAP1 protein 		CTD PMID:9776515 PMID:10754506 PMID:18563302 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression EXP Cyclophosphamide affects the expression of ADCYAP1R1 mRNA CTD PMID:18563302 NCBI chr 4:85,924,171...85,972,973
Ensembl chr 4:85,924,100...85,972,973 		JBrowse link
G Adm adrenomedullin affects response to substance ISO ADM protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Afp alpha-fetoprotein affects expression ISO Cyclophosphamide affects the expression of AFP protein CTD PMID:6177358 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649 		JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression EXP [doxorubicin cotreated with cyclophosphamide] increased expression of Ager protein in prefrontal cortex and hippocampus RGD PMID:36708885 RGD:597621662 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agl amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase affects response to substance ISO AGL protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:207,389,949...207,445,959
Ensembl chr 2:207,389,949...207,445,724 		JBrowse link
G Akap8 A-kinase anchoring protein 8 increases expression EXP Cyclophosphamide results in increased expression of AKAP8 mRNA CTD PMID:27281708 NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900 		JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 decreases expression
affects expression 		EXP Cyclophosphamide results in decreased expression of AKR1C14 mRNA
Cyclophosphamide affects the expression of AKR1C14 mRNA 		CTD PMID:18246545 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:71,066,200...71,083,157 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression 		EXP Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of AKT1 protein] CTD PMID:19996110 PMID:25446862 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO Cyclophosphamide results in increased expression of ALCAM mRNA CTD PMID:21041162 NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects response to substance
increases expression
decreases response to substance 		ISO ALDH1A1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of ALDH1A1 mRNA
ALDH1A1 protein results in decreased susceptibility to Cyclophosphamide 		CTD PMID:12513786 PMID:17403535 PMID:18854779 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO Cyclophosphamide results in increased expression of ALDH2 mRNA CTD PMID:17403535 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Cyclophosphamide CTD PMID:18854779 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein decreases expression ISO Cyclophosphamide results in decreased expression of ALOX5AP mRNA CTD PMID:17403535 NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038 		JBrowse link
G Alyref Aly/REF export factor decreases expression ISO Cyclophosphamide results in decreased expression of ALYREF mRNA CTD PMID:21041162 NCBI chr10:105,871,424...105,875,076
Ensembl chr10:106,369,750...106,373,395 		JBrowse link
G Amfr autocrine motility factor receptor multiple interactions ISO AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:11,002,451...11,038,182
Ensembl chr19:11,002,101...11,038,364 		JBrowse link
G Amh anti-Mullerian hormone decreases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide results in decreased expression of AMH protein
Donepezil inhibits the reaction [Cyclophosphamide results in decreased expression of AMH protein]; Gly(14)-Humanin inhibits the reaction [Cyclophosphamide results in decreased expression of AMH protein]; Mots-C peptide, mouse inhibits the reaction [Cyclophosphamide results in decreased expression of AMH protein]
Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of AMH protein]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of AMH protein] 		CTD PMID:32456565 PMID:36154502 PMID:38825044 PMID:39079574 PMID:39952379 NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:9,557,451...9,559,867 		JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Cyclophosphamide results in increased expression of ANGPT1 mRNA CTD PMID:17403535 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression EXP Cyclophosphamide results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr10:79,282,075...79,295,322
Ensembl chr10:56,415,260...56,416,345
Ensembl chr10:56,415,260...56,416,345 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of APAF1 mRNA CTD PMID:29445054 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP Cyclophosphamide results in increased expression of APEX1 mRNA; Cyclophosphamide results in increased expression of APEX1 protein CTD PMID:11599041 PMID:15928459 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Apob apolipoprotein B decreases expression EXP Cyclophosphamide results in decreased expression of APOB mRNA CTD PMID:18246545 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoe apolipoprotein E decreases expression
increases expression 		ISO Cyclophosphamide results in decreased expression of APOE mRNA
Cyclophosphamide results in increased expression of APOE mRNA 		CTD PMID:15331540 PMID:21041162 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Apoh apolipoprotein H increases expression EXP Cyclophosphamide results in increased expression of APOH protein CTD PMID:15928459 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127 		JBrowse link
G Arg1 arginase 1 increases expression
decreases expression
affects expression 		ISO
EXP 		Cyclophosphamide results in increased expression of ARG1 mRNA
Cyclophosphamide results in decreased expression of ARG1 mRNA
Cyclophosphamide affects the expression of ARG1 mRNA 		CTD PMID:18246545 PMID:21068404 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Cyclophosphamide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Cyclophosphamide results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 2:148,889,405...149,000,538
Ensembl chr 2:148,889,423...149,000,538 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ASNS mRNA CTD PMID:24356939 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP Cyclophosphamide results in increased expression of ASS1 protein CTD PMID:15928459 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627 		JBrowse link
G Atf2 activating transcription factor 2 increases expression EXP Cyclophosphamide results in increased expression of ATF2 mRNA CTD PMID:11599041 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745 		JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO Cyclophosphamide results in decreased expression of ATF5 mRNA CTD PMID:17403535 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:104,432,094...104,436,183 		JBrowse link
G Atg3 autophagy related 3 decreases expression ISO Cyclophosphamide results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr11:55,624,914...55,653,249
Ensembl chr11:69,121,952...69,159,280 		JBrowse link
G Atg5 autophagy related 5 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of ATG5 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein] 		CTD PMID:32151603 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821 		JBrowse link
G Atg7 autophagy related 7 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of ATG7 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein] 		CTD PMID:32151603 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319 		JBrowse link
G Aurkb aurora kinase B increases expression EXP Cyclophosphamide results in increased expression of AURKB mRNA CTD PMID:11599041 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cyclophosphamide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009 		JBrowse link
G B3galnt2 beta-1,3-N-acetylgalactosaminyltransferase 2 increases expression ISO Cyclophosphamide results in increased expression of B3GALNT2 mRNA CTD PMID:21527772 NCBI chr17:56,030,409...56,072,952
Ensembl chr17:56,030,409...56,072,952 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide results in increased expression of BAD mRNA
Cyclophosphamide results in increased expression of BAD protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAD protein] 		CTD PMID:11599041 PMID:29753871 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bag1 BAG cochaperone 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BAG1 mRNA CTD PMID:16322899 NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide results in increased expression of BAX mRNA; Cyclophosphamide results in increased expression of BAX protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; Mots-C peptide, mouse inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of BAX mRNA]
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; coenzyme Q10 inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein] 		CTD PMID:25446862 PMID:29753871 PMID:30506662 PMID:32197949 PMID:36154502 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of BBC3 mRNA
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA] 		CTD PMID:32197949 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 multiple interactions ISO BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:68,627,739...68,661,232
Ensembl chr 8:68,627,656...68,661,358 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity 		ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein
Cyclophosphamide results in decreased activity of BCHE protein 		CTD PMID:4672170 PMID:4959505 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression 		ISO
EXP 		[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of BCL2 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of BCL2 protein; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BCL2 mRNA; [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]; Cyclophosphamide promotes the reaction [SGI-1027 results in decreased expression of BCL2 protein]; PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Valproic Acid inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Cyclophosphamide results in increased expression of BCL2 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Mots-C peptide, mouse inhibits the reaction [Cyclophosphamide results in increased expression of BCL2 protein]
Cyclophosphamide results in decreased expression of BCL2 mRNA; Cyclophosphamide results in decreased expression of BCL2 protein
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; herbacetin inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Cyclophosphamide results in increased expression of BCL2 mRNA 		CTD PMID:11723234 PMID:14503796 PMID:15582267 PMID:16322899 PMID:21182165 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression 		EXP
ISO 		Cyclophosphamide results in increased expression of BCL2L1 mRNA
Cyclophosphamide results in decreased expression of BCL2L1 mRNA 		CTD PMID:11599041 PMID:33737021 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of BCL2L11 mRNA
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA] 		CTD PMID:32197949 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO Cyclophosphamide results in increased expression of BCL2L2 mRNA CTD PMID:21041162 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379 		JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Cyclophosphamide results in decreased expression of BCL6 mRNA
Cyclophosphamide metabolite results in decreased expression of BCL6 mRNA 		CTD PMID:21041162 PMID:24356939 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 affects response to substance ISO BDH1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636 		JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression EXP Cyclophosphamide results in increased expression of BDKRB1 mRNA CTD PMID:10498854 PMID:15576455 NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973 		JBrowse link
G Bdkrb2 bradykinin receptor B2 affects expression EXP Cyclophosphamide affects the expression of BDKRB2 mRNA CTD PMID:15576455 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
decreases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of BDNF mRNA; Cyclophosphamide results in increased expression of BDNF protein
Cyclophosphamide results in decreased expression of BDNF protein
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of BDNF protein]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of BDNF protein] 		CTD PMID:10683293 PMID:32615180 PMID:39209270 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
decreases expression 		ISO BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Cyclophosphamide results in increased expression of BECN1 protein
asperuloside promotes the reaction [Cyclophosphamide results in increased expression of BECN1 protein]; CSF2 protein promotes the reaction [Cyclophosphamide results in increased expression of BECN1 protein]; dorsomorphin inhibits the reaction [asperuloside promotes the reaction [Cyclophosphamide results in increased expression of BECN1 protein]]; dorsomorphin inhibits the reaction [Cyclophosphamide results in increased expression of BECN1 protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein] 		CTD PMID:16896004 PMID:32151603 PMID:38348709 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Bik BCL2-interacting killer decreases expression ISO Cyclophosphamide results in decreased expression of BIK mRNA CTD PMID:17403535 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of BIRC3 mRNA CTD PMID:24356939 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Blvrb biliverdin reductase B decreases expression EXP Cyclophosphamide results in decreased expression of BLVRB protein CTD PMID:9006340 NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225 		JBrowse link
G Bpi bactericidal/permeability-increasing protein decreases expression ISO Cyclophosphamide results in decreased expression of BPI mRNA CTD PMID:17403535 NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:167,329,530...167,356,396 		JBrowse link
G Brpf1 bromodomain and PHD finger containing, 1 increases expression EXP Cyclophosphamide results in increased expression of BRPF1 mRNA CTD PMID:27281708 NCBI chr 4:148,011,977...148,028,431
Ensembl chr 4:148,011,931...148,028,424 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Cyclophosphamide results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:215,160,764...215,172,540
Ensembl chr 1:215,160,957...215,172,536 		JBrowse link
G Bsg basigin decreases expression ISO Cyclophosphamide results in decreased expression of BSG mRNA CTD PMID:15331540 NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of BTG1 mRNA CTD PMID:21041162 NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Cyclophosphamide results in increased expression of BTG2 mRNA CTD PMID:29445054 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 multiple interactions ISO BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:30,517,072...30,533,082 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BUB3 mRNA CTD PMID:16322899 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:195,758,105...195,791,028 		JBrowse link
G C1qa complement C1q A chain increases expression ISO Cyclophosphamide results in increased expression of C1QA mRNA CTD PMID:21041162 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732 		JBrowse link
G C3 complement C3 increases expression ISO Cyclophosphamide results in increased expression of C3 mRNA CTD PMID:21041162 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465 		JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP Cyclophosphamide results in decreased expression of CA3 protein CTD PMID:15928459 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Cabp1 calcium binding protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of CABP1 mRNA CTD PMID:11906922 NCBI chr12:47,045,914...47,109,614
Ensembl chr12:47,085,292...47,109,611 		JBrowse link
G Cabp2 calcium binding protein 2 decreases expression EXP Cyclophosphamide results in decreased expression of CABP2 mRNA CTD PMID:11906922 NCBI chr 1:201,374,649...201,380,469
Ensembl chr 1:210,804,096...210,809,940 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of CACNA1H protein
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein 		CTD PMID:29129814 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of CALCA protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of CALCA protein] 		CTD PMID:32615180 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Calr calreticulin increases expression
decreases expression 		EXP Cyclophosphamide results in increased expression of CALR mRNA; Cyclophosphamide results in increased expression of CALR protein
Cyclophosphamide results in decreased expression of CALR mRNA 		CTD PMID:11599041 PMID:11906922 PMID:15928459 PMID:18246545 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236 		JBrowse link
G Canx calnexin decreases expression EXP Cyclophosphamide results in decreased expression of CANX mRNA CTD PMID:11906922 NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857 		JBrowse link
G Capn2 calpain 2 increases expression ISO Cyclophosphamide results in increased expression of CAPN2 mRNA CTD PMID:21041162 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression
increases expression 		ISO Cyclophosphamide results in decreased expression of CA2 mRNA
Cyclophosphamide results in increased expression of CAR2 mRNA 		CTD PMID:15331540 PMID:17403535 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Car7 carbonic anhydrase 7 decreases expression EXP Cyclophosphamide results in decreased expression of CAR7 mRNA CTD PMID:27281708 NCBI chr19:429,063...438,478
Ensembl chr19:435,522...452,384 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CARS1 mRNA CTD PMID:24356939 NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407 		JBrowse link
G Casp1 caspase 1 decreases expression
increases expression
multiple interactions 		ISO
EXP 		Cyclophosphamide results in decreased expression of CASP1 mRNA
Cyclophosphamide results in increased expression of CASP1 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CASP1 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CASP1 protein]
Cyclophosphamide results in increased expression of CASP1 mRNA 		CTD PMID:17403535 PMID:21041162 PMID:35762198 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp12 caspase 12 increases cleavage EXP Cyclophosphamide results in increased cleavage of CASP12 protein CTD PMID:38740238 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
decreases response to substance 		ISO
EXP 		[Bortezomib co-treated with oblimersen co-treated with Cyclophosphamide] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Cyclophosphamide promotes the reaction [SGI-1027 results in increased cleavage of CASP3 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP3 protein; PAX5 protein affects the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; SGI-1027 promotes the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; Valproic Acid inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]
Cyclophosphamide results in increased expression of CASP3 mRNA; Cyclophosphamide results in increased expression of CASP3 protein
Berberine inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; coenzyme Q10 inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; Cyclophosphamide results in increased expression of and results in increased activity of CASP3 protein; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 mRNA]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of and results in increased activity of CASP3 protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]
Donepezil inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; levocabastine inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of CASP3 mRNA]
CASP3 protein alternative form results in decreased susceptibility to Cyclophosphamide 		CTD PMID:11723234 PMID:14503796 PMID:16675587 PMID:17020986 PMID:17898787 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp4 caspase 4 increases cleavage
multiple interactions 		EXP Cyclophosphamide results in increased cleavage of CASP4 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein] 		CTD PMID:32197949 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance 		ISO [Methotrexate results in increased expression of CASP8 protein] which results in increased susceptibility to Cyclophosphamide metabolite; Cyclophosphamide metabolite results in increased expression of and results in increased cleavage of CASP8 protein; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP8 protein
CASP8 protein results in increased susceptibility to Cyclophosphamide metabolite 		CTD PMID:17898787 PMID:22010212 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity 		ISO
EXP 		BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP9 protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP9 protein]
Cyclophosphamide results in increased expression of CASP9 mRNA; Cyclophosphamide results in increased expression of CASP9 protein 		CTD PMID:11723234 PMID:17898787 PMID:30506662 PMID:39952379 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases expression
decreases activity
affects activity
multiple interactions 		EXP
ISO 		Cyclophosphamide results in decreased expression of CAT protein
Cyclophosphamide results in decreased activity of CAT protein
Cyclophosphamide results in decreased expression of CAT mRNA; Cyclophosphamide results in decreased expression of CAT protein
Cyclophosphamide affects the activity of CAT protein
Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]; cinnamic acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Eicosapentaenoic Acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; levocabastine inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CAT mRNA]
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; crocin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; herbacetin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; naringin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; pimagedine inhibits the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein] 		CTD PMID:16076520 PMID:19107871 PMID:20052769 PMID:20957680 PMID:21772021 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccin calicin increases expression ISO Cyclophosphamide results in increased expression of CCIN protein CTD PMID:17475930 NCBI chr 5:63,002,427...63,004,314
Ensembl chr 5:63,000,138...63,010,123 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
increases expression 		EXP
ISO 		Cyclophosphamide results in decreased expression of CCL2 protein
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]
naringin inhibits the reaction [Cyclophosphamide results in increased expression of CCL2 mRNA] 		CTD PMID:18848347 PMID:21068404 PMID:33992719 PMID:36416909 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 decreases expression ISO Cyclophosphamide results in decreased expression of CCL25 mRNA CTD PMID:21041162 NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of CCL3 protein
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] 		CTD PMID:21880982 PMID:36416909 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Cyclophosphamide results in increased expression of CCL7 mRNA CTD PMID:15331540 PMID:21041162 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947 		JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of CCN1 mRNA; Cyclophosphamide results in decreased expression of CCN1 protein
Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN1 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN1 protein] 		CTD PMID:36154502 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of CCN2 mRNA; Cyclophosphamide results in decreased expression of CCN2 protein
Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN2 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN2 protein] 		CTD PMID:36154502 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Cyclophosphamide results in decreased expression of CCNA2 mRNA CTD PMID:21041162 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Cyclophosphamide results in decreased expression of CCND1 protein CTD PMID:33737021 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Cyclophosphamide results in increased expression of CCND2 mRNA CTD PMID:21041162 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Cyclophosphamide results in decreased expression of CCND3 mRNA CTD PMID:21041162 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Cyclophosphamide results in increased expression of CCR5 mRNA CTD PMID:15331540 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 decreases expression ISO Cyclophosphamide results in decreased expression of CCR8 mRNA CTD PMID:17403535 NCBI chr 8:128,703,966...128,705,926
Ensembl chr 8:128,702,349...128,705,955 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 decreases expression ISO Cyclophosphamide results in decreased expression of CCR9 mRNA CTD PMID:21041162 NCBI chr 8:132,273,581...132,287,651
Ensembl chr 8:132,273,544...132,287,883 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 decreases expression EXP Cyclophosphamide results in decreased expression of CCT3 mRNA CTD PMID:11906922 NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression EXP Cyclophosphamide results in decreased expression of CCT5 mRNA CTD PMID:11906922 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression EXP Cyclophosphamide results in decreased expression of CCT7 mRNA CTD PMID:11906922 NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Cyclophosphamide results in increased expression of CD14 mRNA CTD PMID:15331540 PMID:21041162 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd151 CD151 molecule (Raph blood group) increases expression ISO Cyclophosphamide results in increased expression of CD151 mRNA CTD PMID:21041162 NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:205,994,738...205,998,784 		JBrowse link
G Cd2 Cd2 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD2 mRNA CTD PMID:21041162 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:191,399,510...191,413,665 		JBrowse link
G Cd27 CD27 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD27 mRNA CTD PMID:21041162 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823 		JBrowse link
G Cd28 Cd28 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD28 mRNA CTD PMID:21041162 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192 		JBrowse link
G Cd38 CD38 molecule increases expression ISO Cyclophosphamide results in increased expression of CD38 mRNA CTD PMID:21041162 NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505 		JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex decreases expression ISO Cyclophosphamide results in decreased expression of CD3D mRNA CTD PMID:21041162 NCBI chr 8:54,184,573...54,190,112
Ensembl chr 8:54,175,155...54,196,722 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex decreases expression ISO Cyclophosphamide results in decreased expression of CD3E mRNA CTD PMID:21041162 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:54,200,617...54,211,876 		JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex decreases expression ISO Cyclophosphamide results in decreased expression of CD3G mRNA CTD PMID:21041162 NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918 		JBrowse link
G Cd4 Cd4 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD4 mRNA CTD PMID:21041162 NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461 		JBrowse link
G Cd40 CD40 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD40 mRNA CTD PMID:21041162 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd5 Cd5 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD5 mRNA CTD PMID:21041162 NCBI chr 1:216,790,245...216,811,209
Ensembl chr 1:216,790,245...216,811,209 		JBrowse link
G Cd6 Cd6 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD6 mRNA CTD PMID:21041162 NCBI chr 1:216,867,767...216,906,642
Ensembl chr 1:216,867,771...216,879,432 		JBrowse link
G Cd69 Cd69 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD69 mRNA
Cyclophosphamide metabolite results in decreased expression of CD69 mRNA 		CTD PMID:21041162 PMID:24356939 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Cd74 CD74 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD74 mRNA CTD PMID:15331540 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Cd79b CD79b molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD79B mRNA CTD PMID:15331540 NCBI chr10:91,739,134...91,742,312
Ensembl chr10:91,739,137...91,742,405 		JBrowse link
G Cd83 CD83 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD83 mRNA CTD PMID:15331540 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047 		JBrowse link
G Cd84 CD84 molecule increases expression ISO Cyclophosphamide metabolite results in increased expression of CD84 mRNA CTD PMID:24356939 NCBI chr13:86,859,979...86,899,984
Ensembl chr13:86,859,990...86,894,318 		JBrowse link
G Cd8a CD8 subunit alpha decreases expression ISO Cyclophosphamide results in decreased expression of CD8A mRNA CTD PMID:21041162 NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:104,900,833...104,928,358 		JBrowse link
G Cd8b CD8 subunit beta decreases expression ISO Cyclophosphamide results in decreased expression of CD8B1 mRNA CTD PMID:21041162 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:104,870,893...104,886,868 		JBrowse link
G Cdc20 cell division cycle 20 increases expression EXP Cyclophosphamide results in increased expression of CDC20 mRNA CTD PMID:11599041 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799 		JBrowse link
G Cdh1 cadherin 1 affects expression EXP Cyclophosphamide affects the expression of CDH1 mRNA CTD PMID:10859244 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdh2 cadherin 2 affects expression EXP Cyclophosphamide affects the expression of CDH2 mRNA CTD PMID:10859244 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cdh3 cadherin 3 affects expression EXP Cyclophosphamide affects the expression of CDH3 mRNA CTD PMID:10859244 NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Cyclophosphamide results in decreased expression of CDK2 mRNA CTD PMID:21041162 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Cyclophosphamide results in increased expression of CDKN1A mRNA CTD PMID:15331540 PMID:21527772 PMID:29445054 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CDKN1B mRNA CTD PMID:16322899 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Cyclophosphamide results in increased expression of CDKN1C mRNA CTD PMID:21041162 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression ISO Cyclophosphamide results in decreased expression of CDKN2D mRNA CTD PMID:21041162 NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CEBPB mRNA CTD PMID:24356939 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Cyclophosphamide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019 		JBrowse link
G Cfb complement factor B increases expression ISO Cyclophosphamide results in increased expression of CFB mRNA CTD PMID:21041162 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740 		JBrowse link
G Cfi complement factor I affects response to substance ISO CFI protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CHAC1 mRNA; Cyclophosphamide results in decreased expression of CHAC1 mRNA CTD PMID:23824090 PMID:24356939 NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361 		JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 increases expression EXP Cyclophosphamide results in increased expression of CHAMP1 mRNA CTD PMID:27281708 NCBI chr16:75,733,958...75,744,931
Ensembl chr16:82,434,823...82,458,984 		JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 decreases expression EXP Cyclophosphamide results in decreased expression of CHD5 mRNA CTD PMID:27281708 NCBI chr 5:168,130,851...168,181,705
Ensembl chr 5:168,130,575...168,179,441 		JBrowse link
G Chga chromogranin A decreases expression ISO Cyclophosphamide results in decreased expression of CHGA mRNA CTD PMID:15331540 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 increases expression EXP Cyclophosphamide results in increased expression of CHRM5 protein CTD PMID:16125470 NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:119,735,975...119,792,166 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression
decreases expression 		EXP Cyclophosphamide affects the expression of CITED2 mRNA
Cyclophosphamide results in decreased expression of CITED2 mRNA 		CTD PMID:18246545 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions
increases expression 		EXP Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CKM protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CKM protein] CTD PMID:35762198 NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719 		JBrowse link
G Cldn1 claudin 1 multiple interactions
decreases expression 		ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein] CTD PMID:32151603 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529 		JBrowse link
G Cldn4 claudin 4 multiple interactions
decreases expression 		EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958 		JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO Cyclophosphamide results in increased expression of CLIC4 mRNA CTD PMID:15331540 NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of CLIP1 mRNA CTD PMID:27281708 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:38,571,834...38,678,779 		JBrowse link
G Coch cochlin affects response to substance ISO COCH protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:74,766,485...74,780,504
Ensembl chr 6:74,766,419...74,780,502 		JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO Cyclophosphamide results in increased expression of COMT mRNA CTD PMID:21041162 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO Cyclophosphamide results in decreased expression of COX7A2 mRNA CTD PMID:17403535 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:55,514,261...55,514,512
Ensembl chr 8:55,514,261...55,514,512 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO Cyclophosphamide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:175,707,312...175,728,385 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of CREB1 protein modified form CTD PMID:18299998 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crem cAMP responsive element modulator decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of CREM mRNA; Cyclophosphamide results in decreased expression of CREM protein
Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM mRNA]; Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM protein] 		CTD PMID:17624719 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crh corticotropin releasing hormone increases expression EXP
ISO 		Cyclophosphamide results in increased expression of CRH mRNA; Cyclophosphamide results in increased expression of CRH protein CTD PMID:15276878 PMID:16614059 PMID:17335920 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 increases expression EXP Cyclophosphamide results in increased expression of CRHR2 protein CTD PMID:16614059 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:85,554,268...85,596,318 		JBrowse link
G Crp C-reactive protein multiple interactions
increases secretion 		EXP allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of CRP protein] CTD PMID:31779506 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO [Cyclophosphamide co-treated with Sizofiran] results in increased expression of CSF1 mRNA CTD PMID:10052129 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468 		JBrowse link
G Csf2 colony stimulating factor 2 affects activity
decreases expression
multiple interactions
increases expression 		ISO
EXP 		CSF2 protein affects the activity of Cyclophosphamide
Cyclophosphamide results in decreased expression of CSF2 protein
asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of CSF2 protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in decreased expression of EPO protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in decreased expression of KIT protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in decreased expression of THPO protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]; CSF2 protein promotes the reaction [Cyclophosphamide results in increased expression of BECN1 protein]; CSF2 protein promotes the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein]; CSF2 protein promotes the reaction [Cyclophosphamide results in increased phosphorylation of PRKAA1 protein]; dorsomorphin inhibits the reaction [asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of CSF2 protein]]
Cyclophosphamide results in increased expression of CSF2 protein 		CTD PMID:8349185 PMID:18848347 PMID:38348709 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csk C-terminal Src kinase decreases expression ISO Cyclophosphamide results in decreased expression of CSK mRNA CTD PMID:21041162 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:66,925,651...66,930,274 		JBrowse link
G Cst7 cystatin F decreases expression ISO Cyclophosphamide results in decreased expression of CST7 mRNA CTD PMID:17403535 NCBI chr 3:159,857,221...159,865,987
Ensembl chr 3:159,857,052...159,866,919 		JBrowse link
G Csta cystatin A decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CSTA mRNA CTD PMID:24356939 NCBI chr11:78,125,813...78,136,818
Ensembl chr11:78,125,800...78,136,822 		JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Cyclophosphamide results in increased expression of CTH protein CTD PMID:29129814 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression 		EXP coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of CTNNB1 protein] CTD PMID:39209270 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CTNNBIP1 mRNA CTD PMID:16322899 NCBI chr 5:165,245,019...165,293,994
Ensembl chr 5:165,245,098...165,293,991 		JBrowse link
G Ctnnd2 catenin delta 2 multiple interactions ISO CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:82,879,469...83,727,409
Ensembl chr 2:82,879,469...83,727,409 		JBrowse link
G Ctsd cathepsin D multiple interactions
increases activity 		ISO
EXP 		[Cyclophosphamide co-treated with Mecamylamine] results in increased expression of CTSD mRNA
Cyclophosphamide results in increased activity of CTSD protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein] 		CTD PMID:18433785 PMID:25451569 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ctsh cathepsin H increases expression ISO Cyclophosphamide results in increased expression of CTSH mRNA CTD PMID:17403535 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181 		JBrowse link
G Ctsl cathepsin L increases expression
decreases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of CTSL mRNA
Cyclophosphamide results in decreased expression of CTSL mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of CTSL mRNA] 		CTD PMID:17403535 PMID:30760223 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Cyclophosphamide results in increased expression of CX3CL1 protein CTD PMID:16651033 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression EXP Cyclophosphamide results in increased expression of CX3CR1 protein CTD PMID:16651033 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Cyclophosphamide results in increased expression of CXCL1 protein CTD PMID:18848347 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 affects expression
increases expression
increases response to substance 		ISO Cyclophosphamide affects the expression of CXCL10 mRNA
Cyclophosphamide results in increased expression of CXCL10 protein
CXCL10 protein results in increased susceptibility to Cyclophosphamide 		CTD PMID:18957084 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Cyclophosphamide results in increased expression of CXCL11 protein CTD PMID:18957084 NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 affects expression
increases expression 		ISO
EXP 		Cyclophosphamide affects the expression of CXCL12 mRNA
Cyclophosphamide results in increased expression of CXCL12 mRNA; Cyclophosphamide results in increased expression of CXCL12 protein 		CTD PMID:12624490 PMID:16337237 PMID:19066630 PMID:20032115 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Cyclophosphamide co-treated with Dexamethasone] inhibits the reaction [Paraquat results in increased expression of CXCL2 mRNA] CTD PMID:36031164 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
affects expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of CXCL1 mRNA; Cyclophosphamide results in increased expression of CXCL1 protein
Cyclophosphamide affects the expression of CXCL3 mRNA
VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of CXCL1 protein] 		CTD PMID:15331540 PMID:18483878 PMID:18957084 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO Cyclophosphamide results in increased expression of CXCL5 mRNA CTD PMID:15331540 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 affects expression
decreases expression
increases expression 		ISO Cyclophosphamide affects the expression of CXCL9 mRNA
Cyclophosphamide results in decreased expression of CXCL9 protein
Cyclophosphamide results in increased expression of CXCL9 mRNA; Cyclophosphamide results in increased expression of CXCL9 protein 		CTD PMID:15331540 PMID:18957084 PMID:21041162 PMID:21880982 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression
increases expression
affects localization 		EXP
ISO 		Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein]
Cyclophosphamide results in decreased expression of CXCR4 mRNA
Cyclophosphamide results in increased expression of CXCR4 mRNA; Cyclophosphamide results in increased expression of CXCR4 protein
Cyclophosphamide affects the localization of CXCR4 protein 		CTD PMID:19066630 PMID:20032115 PMID:21041162 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 increases expression ISO Cyclophosphamide results in increased expression of CXCR6 mRNA CTD PMID:21041162 NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:132,306,600...132,322,498 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide results in decreased expression of CYP11A1 mRNA
Flavonoids inhibits the reaction [Cyclophosphamide results in decreased expression of CYP11A1 mRNA]; Flavonoids inhibits the reaction [Cyclophosphamide results in decreased expression of CYP11A1 protein]
Cyclophosphamide results in decreased expression of CYP11A1 mRNA; Cyclophosphamide results in decreased expression of CYP11A1 protein
[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of CYP11A1 mRNA] 		CTD PMID:38211767 PMID:39239657 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of CYP17A1 mRNA; Cyclophosphamide results in decreased expression of CYP17A1 protein
Flavonoids inhibits the reaction [Cyclophosphamide results in decreased expression of CYP17A1 protein] 		CTD PMID:39239657 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Cyclophosphamide results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Cyclophosphamide results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO Cyclophosphamide results in decreased expression of CYP1B1 mRNA CTD PMID:12167460 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO Cyclophosphamide results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases response to substance
affects metabolic processing
increases activity
increases hydroxylation
increases expression
increases metabolic processing 		EXP Cyclophosphamide results in increased expression of and results in increased activity of CYP2B1 protein; Metyrapone inhibits the reaction [CYP2B1 results in increased susceptibility to Cyclophosphamide]
CYP2B1 protein results in increased susceptibility to Cyclophosphamide; CYP2B1 results in increased susceptibility to Cyclophosphamide
CYP2B1 protein affects the metabolism of Cyclophosphamide
CYP2B1 results in increased activity of Cyclophosphamide
CYP2B1 protein mutant form results in increased hydroxylation of Cyclophosphamide; CYP2B1 protein results in increased hydroxylation of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2B1 mRNA; Cyclophosphamide results in increased expression of CYP2B1 protein
CYP2B1 protein results in increased metabolism of Cyclophosphamide; CYP2B1 results in increased metabolism of Cyclophosphamide 		CTD PMID:2272335 PMID:7834628 PMID:8640822 PMID:9592392 PMID:10415877 More... NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Cyclophosphamide results in increased expression of CYP2B2 mRNA; Cyclophosphamide results in increased expression of CYP2B2 protein CTD PMID:16019949 PMID:17634551 NCBI chr 1:90,722,243...90,736,272 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
increases metabolic processing
increases activity
increases response to substance
increases hydroxylation
affects hydroxylation 		ISO
EXP 		[Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CYP2B6 mRNA; Cyclophosphamide results in decreased expression of and results in decreased activity of CYP2B6 protein; CYP2B6 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide; CYP2B6 protein results in increased metabolism of and results in increased susceptibility to Cyclophosphamide; POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
Cyclophosphamide results in increased expression of CYP2B10 mRNA
CYP2B6 protein results in increased metabolism of Cyclophosphamide
CYP2B6 protein results in increased activity of Cyclophosphamide
CYP2B6 protein results in increased susceptibility to Cyclophosphamide; CYP2B6 results in increased susceptibility to Cyclophosphamide
CYP2B6 protein results in increased hydroxylation of Cyclophosphamide
CYP2B6 intron polymorphism affects the hydroxylation of Cyclophosphamide; CYP2B6 promoter polymorphism affects the hydroxylation of Cyclophosphamide 		CTD PMID:9766669 PMID:10919648 PMID:11389073 PMID:11723234 PMID:12498089 More... NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression
increases activity
increases response to substance
multiple interactions
increases metabolic processing 		EXP
ISO 		Cyclophosphamide results in increased expression of CYP2C11 mRNA
CYP2C18 results in increased activity of Cyclophosphamide
CYP2C18 results in increased susceptibility to Cyclophosphamide
POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]
CYP2C11 results in increased metabolism of Cyclophosphamide 		CTD PMID:9241661 PMID:9766669 PMID:16019949 PMID:20566340 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases metabolic processing
increases expression
increases response to substance
increases hydroxylation
increases activity
multiple interactions
decreases metabolic processing 		EXP
ISO 		CYP2C6 results in increased metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2C29 mRNA
CYP2C19 protein results in increased susceptibility to Cyclophosphamide
CYP2C19 protein results in increased hydroxylation of Cyclophosphamide
CYP2C19 results in increased activity of Cyclophosphamide
CYP2C19 protein results in increased metabolism of Cyclophosphamide
[CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide; [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein; CYP2C19 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide
CYP2C19 gene polymorphism results in decreased metabolism of Cyclophosphamide 		CTD PMID:9241661 PMID:15248218 PMID:16116487 PMID:20566340 PMID:24819615 More... NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases activity ISO CYP2C8 results in increased activity of Cyclophosphamide CTD PMID:9241661
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of Cyclophosphamide CTD PMID:11377097 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing
increases expression 		EXP CYP2E1 results in increased metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2E1 protein 		CTD PMID:20566340 PMID:38740238 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases response to substance
increases hydroxylation
affects metabolic processing
affects response to substance
increases metabolic processing
multiple interactions 		EXP
ISO 		Cyclophosphamide results in increased expression of CYP3A2 mRNA; Cyclophosphamide results in increased expression of CYP3A2 protein
Cyclophosphamide results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased susceptibility to Cyclophosphamide
CYP3A4 protein results in increased hydroxylation of Cyclophosphamide
CYP3A4 protein affects the metabolism of Cyclophosphamide
CYP3A4 gene polymorphism affects the susceptibility to Cyclophosphamide
CYP3A4 protein results in increased metabolism of Cyclophosphamide
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [CYP3A4 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide; [CYP3A4 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein; CYP3A4 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]; CYP3A4 protein results in increased metabolism of and results in increased susceptibility to Cyclophosphamide 		CTD PMID:11377097 PMID:16019949 PMID:16087946 PMID:17041008 PMID:18839173 More... NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
decreases expression 		EXP Cyclophosphamide affects the expression of CYP3A23-3A1 mRNA
Cyclophosphamide results in decreased expression of CYP3A23-3A1 mRNA 		CTD PMID:18246545 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
increases expression
multiple interactions
affects response to substance 		ISO CYP3A5 protein affects the metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP3A13 mRNA
CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
CYP3A5 gene polymorphism affects the susceptibility to Cyclophosphamide 		CTD PMID:16087946 PMID:24819615 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Dcn decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 increases expression EXP Cyclophosphamide results in increased expression of DDB1 mRNA CTD PMID:11056294 NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression
multiple interactions
decreases expression 		EXP
ISO 		Cyclophosphamide affects the expression of DDIT3 mRNA
Cyclophosphamide results in increased expression of DDIT3 mRNA; Cyclophosphamide results in increased expression of DDIT3 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]
Cyclophosphamide metabolite results in decreased expression of DDIT3 mRNA 		CTD PMID:18246545 PMID:24356939 PMID:32197949 PMID:38740238 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects response to substance ISO DDIT4 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037 		JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression EXP Cyclophosphamide results in decreased expression of DEAF1 mRNA CTD PMID:27281708 NCBI chr 1:205,831,428...205,865,106
Ensembl chr 1:205,831,336...205,865,106 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein increases expression ISO Cyclophosphamide results in increased expression of DLC1 mRNA CTD PMID:17403535 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 affects expression
increases expression 		EXP
ISO 		Cyclophosphamide affects the expression of DNAJB1 mRNA
Cyclophosphamide metabolite results in increased expression of DNAJB1 mRNA 		CTD PMID:18246545 PMID:24356939 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Cyclophosphamide metabolite results in increased expression of DNAJB4 mRNA CTD PMID:24356939 NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO Cyclophosphamide results in increased expression of DNAJB6 protein CTD PMID:17475930 NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:6,128,070...6,232,005 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression
increases expression
decreases methylation 		ISO Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]; SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of DNMT1 protein]
Cyclophosphamide results in increased expression of DNMT1 protein
Cyclophosphamide results in decreased methylation of DNMT1 protein 		CTD PMID:22007908 PMID:34658283 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of DNMT3B protein
SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of DNMT3B protein] 		CTD PMID:34658283 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313 		JBrowse link
G Dntt DNA nucleotidylexotransferase decreases expression ISO Cyclophosphamide results in decreased expression of DNTT mRNA CTD PMID:21041162 NCBI chr 1:249,805,802...249,837,685
Ensembl chr 1:249,805,802...249,837,684 		JBrowse link
G Dpf3 double PHD fingers 3 decreases expression EXP Cyclophosphamide results in decreased expression of DPF3 mRNA CTD PMID:27281708 NCBI chr 6:102,841,403...103,125,558
Ensembl chr 6:108,577,183...108,856,798 		JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Cyclophosphamide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:203,311,694...203,328,523 		JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Cyclophosphamide binds to DRD1 protein CTD PMID:11180191 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Drd2 dopamine receptor D2 affects binding ISO Cyclophosphamide binds to DRD2 protein CTD PMID:11180191 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Dusp10 dual specificity phosphatase 10 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of DUSP10 mRNA CTD PMID:24356939 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp2 dual specificity phosphatase 2 decreases expression ISO Cyclophosphamide results in decreased expression of DUSP2 mRNA CTD PMID:21041162 NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809 		JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 increases expression ISO Cyclophosphamide results in increased expression of DZIP1 mRNA CTD PMID:17403535 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:102,363,392...102,417,085 		JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions ISO E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725 		JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO Cyclophosphamide results in increased expression of EDA2R mRNA CTD PMID:21527772 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:66,236,111...66,280,663 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Cyclophosphamide results in increased expression of EDN1 protein CTD PMID:17562616 PMID:18548196 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Cyclophosphamide results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression EXP Cyclophosphamide results in decreased expression of EEF2 mRNA CTD PMID:18246545 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Cyclophosphamide results in increased expression of EGR1 mRNA
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein
Cyclophosphamide results in increased expression of EGR1 protein
Cyclophosphamide results in decreased expression of EGR1 mRNA 		CTD PMID:7498375 PMID:9776515 PMID:21041162 PMID:21527772 PMID:29129814 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Egr2 early growth response 2 decreases expression ISO Cyclophosphamide results in decreased expression of EGR2 mRNA CTD PMID:21041162 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748 		JBrowse link
G Egr4 early growth response 4 decreases expression EXP Cyclophosphamide results in decreased expression of EGR4 mRNA CTD PMID:27281708 NCBI chr 4:119,605,358...119,607,817
Ensembl chr 4:119,605,357...119,608,368 		JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF1AX mRNA CTD PMID:16322899 NCBI chr  X:39,307,320...39,322,023
Ensembl chr  X:39,307,137...39,322,021 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
multiple interactions 		EXP Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein] 		CTD PMID:32197949 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF4EBP1 mRNA CTD PMID:16322899 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 affects response to substance ISO ELOVL2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Cyclophosphamide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365 		JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Cyclophosphamide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 1:105,525,086...105,528,370
Ensembl chr 1:105,525,088...105,528,265 		JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 decreases expression ISO Cyclophosphamide results in decreased expression of EPB41L2 mRNA CTD PMID:17403535 NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:21,682,335...21,857,105 		JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression
increases expression 		EXP Cyclophosphamide affects the expression of EPHX1 mRNA
Cyclophosphamide results in increased expression of EPHX1 mRNA 		CTD PMID:18246545 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981 		JBrowse link
G Epo erythropoietin multiple interactions
decreases expression
increases response to substance 		EXP
ISO 		angelicae sinensis extract inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]; Astragali compound inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]
asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of EPO protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in decreased expression of EPO protein]; dorsomorphin inhibits the reaction [asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of EPO protein]]
EPO protein results in increased susceptibility to Cyclophosphamide 		CTD PMID:11245434 PMID:19627214 PMID:38348709 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression EXP Cyclophosphamide results in increased expression of ERAP1 mRNA CTD PMID:27281708 NCBI chr 2:5,666,337...5,705,256
Ensembl chr 2:5,666,436...5,740,056 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO ERBB2 affects the susceptibility to [Doxorubicin co-treated with Cyclophosphamide co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; ERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin] CTD PMID:9816327 PMID:15834928 PMID:15940066 PMID:16446318 PMID:16682728 More... NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit affects expression EXP Cyclophosphamide affects the expression of ERCC1 mRNA CTD PMID:11906922 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit affects expression
increases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide affects the expression of ERCC2 mRNA
Cyclophosphamide results in increased expression of ERCC2 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of ERCC2 mRNA] 		CTD PMID:11906922 PMID:30760223 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102 		JBrowse link
G Erg ETS transcription factor ERG increases expression ISO Cyclophosphamide results in increased expression of ERG mRNA CTD PMID:17403535 NCBI chr11:48,148,149...48,370,472
Ensembl chr11:48,148,153...48,370,688 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation
multiple interactions 		EXP Cyclophosphamide results in increased phosphorylation of ERN1 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein] 		CTD PMID:32197949 PMID:38740238 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR1 mRNA CTD PMID:16322899 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR2 mRNA CTD PMID:16322899 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Esrra estrogen related receptor, alpha decreases expression
increases expression 		EXP Cyclophosphamide results in decreased expression of ESRRA mRNA
Cyclophosphamide results in increased expression of ESRRA mRNA 		CTD PMID:27281708 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811 		JBrowse link
G Evi2a ecotropic viral integration site 2A decreases expression ISO Cyclophosphamide metabolite results in decreased expression of EVI2A mRNA CTD PMID:24356939 NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression EXP Cyclophosphamide results in increased expression of F2RL1 protein CTD PMID:15643279 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954 		JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP Cyclophosphamide results in increased expression of F2RL2 protein CTD PMID:15643279 NCBI chr 2:28,706,766...28,711,808
Ensembl chr 2:28,706,501...28,712,473 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 increases expression EXP Cyclophosphamide results in increased expression of F2RL3 protein CTD PMID:15643279 NCBI chr16:17,151,516...17,153,509
Ensembl chr16:17,151,516...17,153,823 		JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO Cyclophosphamide results in decreased expression of F3 mRNA CTD PMID:17403535 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fam107b family with sequence similarity 107, member B decreases expression ISO Cyclophosphamide metabolite results in decreased expression of FAM107B mRNA CTD PMID:24356939 NCBI chr17:74,478,608...74,685,027
Ensembl chr17:79,387,795...79,594,288 		JBrowse link
G Fam234b family with sequence similarity 234, member B multiple interactions ISO FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:168,048,313...168,124,017
Ensembl chr 4:169,779,737...169,828,678 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
decreases expression
increases expression 		ISO
EXP 		[Cyclophosphamide co-treated with cacalol] results in decreased expression of FAS protein; [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FAS
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of FAS mRNA]
Cyclophosphamide metabolite results in decreased expression of FAS mRNA
Cyclophosphamide results in increased expression of FAS mRNA; Cyclophosphamide results in increased expression of FAS protein 		CTD PMID:10393266 PMID:16166447 PMID:20665104 PMID:24356939 PMID:25446862 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions ISO [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FASLG CTD PMID:16166447 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion increases expression EXP Cyclophosphamide results in increased expression of FAU mRNA CTD PMID:11599041 NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:212,779,473...212,781,026
Ensembl chr 1:212,779,473...212,781,026 		JBrowse link
G Fbxo40 F-box protein 40 increases expression EXP Cyclophosphamide results in increased expression of FBXO40 mRNA CTD PMID:27281708 NCBI chr11:63,794,452...63,812,697
Ensembl chr11:77,300,013...77,318,086 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 increases expression ISO Cyclophosphamide results in increased expression of FBXW7 mRNA CTD PMID:29445054 NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:172,447,738...172,609,591 		JBrowse link
G Fcer1g Fc epsilon receptor Ig increases expression ISO Cyclophosphamide results in increased expression of FCER1G mRNA CTD PMID:21041162 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859 		JBrowse link
G Fcgr2a Fc gamma receptor 2A increases expression ISO Cyclophosphamide results in increased expression of FCGR3 mRNA CTD PMID:21041162 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394 		JBrowse link
G Fcgrt Fc gamma receptor and transporter increases expression ISO Cyclophosphamide results in increased expression of FCGRT mRNA CTD PMID:21041162 NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:104,710,909...104,720,532 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Cyclophosphamide results in increased expression of FHL1 mRNA CTD PMID:23558518 NCBI chr  X:139,592,794...139,652,290
Ensembl chr  X:139,592,604...139,652,282 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects response to substance ISO FKBP1B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:33,551,583...33,570,055
Ensembl chr 6:33,558,517...33,568,129 		JBrowse link
G Fkbpl FKBP prolyl isomerase like increases expression ISO Cyclophosphamide results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr20:4,104,457...4,105,927
Ensembl chr20:4,104,019...4,105,615 		JBrowse link
G Flnc filamin C increases expression ISO Cyclophosphamide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,999,547...59,027,240 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand affects expression ISO Cyclophosphamide affects the expression of FLT3L mRNA CTD PMID:12624490 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B affects response to substance ISO FNDC3B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO
EXP 		Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]
Cyclophosphamide results in increased expression of FOS protein
alfuzosin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein] 		CTD PMID:7498375 PMID:8801120 PMID:8808730 PMID:9776515 PMID:10749792 More... NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Foxp3 forkhead box P3 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of FOXP3 mRNA; Cyclophosphamide results in decreased expression of FOXP3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein] 		CTD PMID:15591121 PMID:32151603 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Foxp4 forkhead box P4 decreases expression EXP Cyclophosphamide results in decreased expression of FOXP4 mRNA CTD PMID:27281708 NCBI chr 9:20,556,270...20,612,967
Ensembl chr 9:20,556,270...20,612,967 		JBrowse link
G Fpr2 formyl peptide receptor 2 increases expression ISO Cyclophosphamide results in increased expression of FPR2 mRNA CTD PMID:15331540 NCBI chr 1:67,449,637...67,458,272
Ensembl chr 1:67,449,637...67,458,272 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO Cyclophosphamide results in increased expression of FSCN1 mRNA CTD PMID:17403535 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression
multiple interactions
decreases secretion 		ISO
EXP 		Cyclophosphamide results in increased expression of FSHB protein
Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of FSHB protein]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of FSHB protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein] 		CTD PMID:6788612 PMID:25446862 PMID:32197949 PMID:32456565 PMID:36154502 More... NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions
decreases expression 		ISO coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of FSHR mRNA] CTD PMID:31557371 NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Cyclophosphamide results in increased expression of FTH1 protein CTD PMID:32129080 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Cyclophosphamide results in increased expression of FTL1 protein CTD PMID:32129080 NCBI chr 1:105,072,858...105,074,705
Ensembl chr  X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Cyclophosphamide results in increased expression of FYN mRNA CTD PMID:17403535 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of G3BP1 mRNA CTD PMID:21041162 NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931 		JBrowse link
G G6pc2 glucose-6-phosphatase catalytic subunit 2 decreases expression ISO Cyclophosphamide results in decreased expression of G6PC2 mRNA CTD PMID:15331540 NCBI chr 3:74,404,976...74,413,391 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
affects expression 		EXP
ISO 		Cyclophosphamide results in increased expression of GADD45A mRNA
Cyclophosphamide affects the expression of GADD45A mRNA 		CTD PMID:18246545 PMID:29445054 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression
increases expression 		EXP
ISO 		Cyclophosphamide affects the expression of GAL mRNA; Cyclophosphamide affects the expression of GAL protein
Cyclophosphamide results in increased expression of GAL mRNA 		CTD PMID:16491427 PMID:17335920 PMID:18563302 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Galc galactosylceramidase affects response to substance ISO GALC protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:123,182,636...123,252,024
Ensembl chr 6:123,182,643...123,245,578 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase multiple interactions ISO GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083 		JBrowse link
G Gap43 growth associated protein 43 increases expression EXP Cyclophosphamide results in increased expression of GAP43 protein CTD PMID:9486479 PMID:10536274 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Gas2 growth arrest-specific 2 increases expression ISO Cyclophosphamide results in increased expression of GAS2 protein CTD PMID:17475930 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:110,717,312...110,718,541 		JBrowse link
G Gata3 GATA binding protein 3 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of GATA3 mRNA; Cyclophosphamide results in decreased expression of GATA3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein] 		CTD PMID:21041162 PMID:32151603 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of GBP1 mRNA CTD PMID:21621594 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802 		JBrowse link
G Gbp4 guanylate binding protein 4 increases expression ISO Cyclophosphamide results in increased expression of GBP3 mRNA CTD PMID:15331540 NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:233,978,486...233,992,120 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression 		ISO Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]
Cyclophosphamide results in decreased expression of GCLC mRNA; Cyclophosphamide results in decreased expression of GCLC protein 		CTD PMID:27633142 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of GCLM mRNA
TRPM2 protein affects the reaction [Cyclophosphamide results in decreased expression of GCLM mRNA] 		CTD PMID:39952379 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gdf9 growth differentiation factor 9 multiple interactions
decreases expression 		ISO Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GDF9 mRNA] CTD PMID:37863343 NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797 		JBrowse link
G Gdnf glial cell derived neurotrophic factor increases expression EXP Cyclophosphamide results in increased expression of GDNF mRNA CTD PMID:10683293 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Cyclophosphamide results in increased expression of GEM mRNA CTD PMID:21041162 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:30,011,592...30,022,542 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO Cyclophosphamide results in decreased expression of GFI1 mRNA CTD PMID:21041162 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,187,286...2,196,730 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501 		JBrowse link
G Gimap4 GTPase, IMAP family member 4 decreases expression EXP Cyclophosphamide results in decreased expression of GIMAP4 mRNA CTD PMID:27466211 NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:78,967,297...78,974,202 		JBrowse link
G Gja1 gap junction protein, alpha 1 affects expression
decreases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide affects the expression of GJA1 mRNA
Cyclophosphamide results in decreased expression of GJA1 mRNA
Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GJA1 mRNA] 		CTD PMID:10859244 PMID:37863343 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gja4 gap junction protein, alpha 4 multiple interactions
decreases expression 		ISO Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GJA4 mRNA] CTD PMID:37863343 NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216 		JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression ISO Cyclophosphamide results in decreased expression of GJB1 mRNA CTD PMID:21621594 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:70,541,862...70,549,843 		JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression EXP Cyclophosphamide results in decreased expression of GLIS1 mRNA CTD PMID:27281708 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:127,451,293...127,640,928 		JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression ISO Cyclophosphamide results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr10:61,077,535...61,095,876 JBrowse link
G Glrb glycine receptor, beta increases expression ISO Cyclophosphamide results in increased expression of GLRB mRNA CTD PMID:17403535 NCBI chr 2:168,432,736...168,505,614
Ensembl chr 2:168,432,736...168,505,614 		JBrowse link
G Gls glutaminase increases expression
affects response to substance 		ISO Cyclophosphamide results in increased expression of GLS mRNA
GLS protein affects the susceptibility to Cyclophosphamide 		CTD PMID:16217747 PMID:21527772 NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861 		JBrowse link
G Gng12 G protein subunit gamma 12 increases expression ISO Cyclophosphamide results in increased expression of GNG12 mRNA CTD PMID:17403535 NCBI chr 4:97,340,830...97,464,422
Ensembl chr 4:97,340,472...97,464,476 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases secretion
multiple interactions 		ISO Cyclophosphamide results in decreased secretion of GNRH1 protein
Flavonoids inhibits the reaction [Cyclophosphamide results in decreased secretion of GNRH1 protein] 		CTD PMID:39239657 NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977
Ensembl chr15:46,148,301...46,148,977 		JBrowse link
G Gpatch8 G patch domain containing 8 increases expression EXP Cyclophosphamide results in increased expression of GPATCH8 mRNA CTD PMID:27281708 NCBI chr10:87,432,020...87,512,594
Ensembl chr10:87,932,174...88,012,523 		JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO Cyclophosphamide results in increased expression of GPR137B mRNA CTD PMID:21527772 NCBI chr17:92,987,792...93,026,003
Ensembl chr17:92,942,559...93,025,911 		JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of GPR18 mRNA CTD PMID:24356939 NCBI chr15:105,404,062...105,407,812
Ensembl chr15:105,404,077...105,408,836 		JBrowse link
G Gpr20 G protein-coupled receptor 20 increases expression ISO Cyclophosphamide results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:107,490,713...107,500,966 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
affects activity
increases activity
multiple interactions 		EXP
ISO 		Cyclophosphamide results in increased expression of GPT protein
Cyclophosphamide affects the activity of GPT protein
Cyclophosphamide results in increased activity of GPT protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]
naringin affects the reaction [Cyclophosphamide affects the activity of GPT protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Cyclophosphamide results in increased expression of GPT protein] 		CTD PMID:25753322 PMID:25779342 PMID:29753871 PMID:30506662 PMID:33992719 More... NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of GPT2 mRNA CTD PMID:24356939 NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
decreases activity
multiple interactions 		ISO
EXP 		Cyclophosphamide results in decreased expression of GPX1 mRNA
Cyclophosphamide results in decreased activity of GPX1 protein
Quercetin inhibits the reaction [Cyclophosphamide results in decreased activity of GPX1 protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of GPX1 mRNA] 		CTD PMID:23542512 PMID:35906875 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Cyclophosphamide results in increased expression of GPX3 mRNA CTD PMID:21041162 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions
decreases expression 		ISO Cyclophosphamide results in increased expression of GPX4 protein
Cyclophosphamide promotes the reaction [Antimony results in decreased expression of and results in increased degradation of GPX4 protein]
Cyclophosphamide results in decreased expression of GPX4 protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in decreased expression of GPX4 protein] 		CTD PMID:17475930 PMID:37690746 PMID:38097005 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions 		EXP Cyclophosphamide results in decreased phosphorylation of GSK3B protein
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased phosphorylation of GSK3B protein] 		CTD PMID:39209270 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity 		ISO
EXP 		[[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein; Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
herbacetin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; naringin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein] 		CTD PMID:12114195 PMID:21772021 PMID:23542512 PMID:25446862 PMID:25753322 More... NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions
decreases expression 		ISO
EXP 		GSTA1 protein affects the metabolism of [Cyclophosphamide metabolite co-treated with Glutathione]
Cyclophosphamide results in decreased expression of GSTA1 protein 		CTD PMID:12516103 PMID:15928459 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]; GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946 PMID:28744217 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Cyclophosphamide results in decreased expression of GSTM2 mRNA CTD PMID:11906922 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
affects response to substance
increases expression 		ISO
EXP 		GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]
GSTP1 protein results in decreased susceptibility to Cyclophosphamide
GSTP1 protein affects the susceptibility to Cyclophosphamide
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
Cyclophosphamide results in increased expression of GSTP1 mRNA; Cyclophosphamide results in increased expression of GSTP1 protein 		CTD PMID:10954901 PMID:12791655 PMID:16141653 PMID:16242832 PMID:19696094 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Gtf2b general transcription factor IIB increases expression EXP Cyclophosphamide results in increased expression of GTF2B mRNA CTD PMID:27281708 NCBI chr 2:234,427,734...234,446,043
Ensembl chr 2:234,427,637...234,446,049 		JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of GTF3C1 mRNA CTD PMID:16322899 NCBI chr 1:189,634,645...189,700,848
Ensembl chr 1:189,634,645...189,700,995 		JBrowse link
G Gusb glucuronidase, beta decreases expression
increases activity
multiple interactions 		EXP Cyclophosphamide results in decreased expression of GUSB protein
Cyclophosphamide results in increased activity of GUSB protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein] 		CTD PMID:17686619 PMID:25451569 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G Gzma granzyme A decreases expression ISO Cyclophosphamide results in decreased expression of GZMA mRNA CTD PMID:21041162 NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696 		JBrowse link
G Gzmb granzyme B increases expression ISO Cyclophosphamide results in increased expression of GZMB mRNA CTD PMID:15331540 NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
increases expression
multiple interactions 		ISO
EXP 		Cyclophosphamide results in increased phosphorylation of H2AX protein
Cyclophosphamide results in increased expression of H2AX protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of H2AX protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of H2AX protein] 		CTD PMID:32482060 PMID:33211169 PMID:34510228 PMID:37690746 PMID:39952379 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO Cyclophosphamide results in increased expression of HAMP mRNA CTD PMID:32129080 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Has2 hyaluronan synthase 2 multiple interactions
decreases expression 		ISO Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of HAS2 mRNA] CTD PMID:37863343 NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of HAVCR1 protein
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of HAVCR1 protein] 		CTD PMID:36198566 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
decreases expression 		EXP O-1602 compound inhibits the reaction [Cyclophosphamide results in decreased expression of HBEGF protein] CTD PMID:32615180 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hcrt hypocretin neuropeptide precursor affects localization
decreases expression 		EXP Cyclophosphamide affects the localization of HCRT protein
Cyclophosphamide results in decreased expression of HCRT mRNA 		CTD PMID:17881193 PMID:19666069 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:86,189,775...86,191,524 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of HES1 protein
SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of HES1 protein]; Valproic Acid inhibits the reaction [Cyclophosphamide results in decreased expression of HES1 protein] 		CTD PMID:34658283 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 multiple interactions ISO PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of HES5 protein] CTD PMID:34658283 NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Cyclophosphamide results in increased expression of HIF1A mRNA CTD PMID:15331540 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hinfp histone H4 transcription factor decreases expression EXP Cyclophosphamide results in decreased expression of HINFP mRNA CTD PMID:27281708 NCBI chr 8:53,525,576...53,541,101
Ensembl chr 8:53,527,236...53,540,555 		JBrowse link
G Hm13 histocompatibility minor 13 decreases expression ISO Cyclophosphamide results in decreased expression of H13 mRNA CTD PMID:15331540 NCBI chr 3:141,145,792...141,183,557
Ensembl chr 3:161,606,052...161,644,805 		JBrowse link
G Hmgb1 high mobility group box 1 increases expression EXP [doxorubicin cotreated with cyclophosphamide] increased expression of Hmgb1 protein in prefrontal cortex and hippocampus RGD PMID:36708885 RGD:597621662 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP Cyclophosphamide results in decreased expression of HMGCS2 protein CTD PMID:15928459 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Hmox1 heme oxygenase 1 affects expression
multiple interactions
decreases expression
increases expression 		EXP
ISO 		Cyclophosphamide affects the expression of HMOX1 mRNA
TRPM2 protein affects the reaction [Cyclophosphamide results in decreased expression of HMOX1 mRNA]
Cyclophosphamide results in decreased expression of HMOX1 mRNA; Cyclophosphamide results in decreased expression of HMOX1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 mRNA]; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Hemin inhibits the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]
Cyclophosphamide results in increased expression of HMOX1 mRNA; Cyclophosphamide results in increased expression of HMOX1 protein 		CTD PMID:11906922 PMID:17979934 PMID:18206168 PMID:18246545 PMID:19952508 More... NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hmox2 heme oxygenase 2 decreases expression EXP Cyclophosphamide results in decreased expression of HMOX2 mRNA CTD PMID:11906922 NCBI chr10:11,303,512...11,337,640
Ensembl chr10:11,303,512...11,318,800 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K increases expression ISO
EXP 		Cyclophosphamide results in increased expression of HNRNPK protein
Cyclophosphamide results in increased expression of HNRNPK mRNA 		CTD PMID:11599041 PMID:17475930 NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565 		JBrowse link
G Hoxa1 homeobox A1 affects response to substance ISO HOXA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:82,586,505...82,589,209
Ensembl chr 4:82,586,505...82,589,209 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO
EXP 		Cyclophosphamide results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 PMID:23677247 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSP90AA1 mRNA CTD PMID:11906922 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSP90AB1 mRNA CTD PMID:11906922 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression
increases expression 		EXP Cyclophosphamide results in decreased expression of HSP90B1 mRNA
Cyclophosphamide results in increased expression of HSP90B1 mRNA 		CTD PMID:11599041 PMID:11906922 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression
increases expression 		EXP
ISO 		Cyclophosphamide affects the expression of HSPA1A mRNA
Cyclophosphamide results in increased expression of HSPA1A mRNA; Cyclophosphamide results in increased expression of HSPA1A protein 		CTD PMID:8917683 PMID:18246545 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression
increases expression
decreases expression 		EXP
ISO 		Cyclophosphamide affects the expression of HSPA1B mRNA
Cyclophosphamide metabolite results in increased expression of HSPA1B mRNA
Cyclophosphamide results in decreased expression of HSPA1B mRNA 		CTD PMID:16141653 PMID:18246545 PMID:24356939 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects response to substance
increases expression 		ISO
EXP 		HSPA2 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of HSPA2 mRNA; Cyclophosphamide results in increased expression of HSPA2 protein 		CTD PMID:11599041 PMID:15928459 PMID:16217747 NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
increases expression 		EXP
ISO 		Cyclophosphamide results in decreased expression of HSPA5 mRNA
Cyclophosphamide results in increased expression of HSPA5 protein
Cyclophosphamide metabolite results in increased expression of HSPA5 mRNA 		CTD PMID:11906922 PMID:24356939 PMID:38740238 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects response to substance ISO HSPA8 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression EXP Cyclophosphamide results in decreased expression of HSPA9 mRNA CTD PMID:11906922 NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression
increases expression 		EXP Cyclophosphamide results in decreased expression of HSPB1 mRNA
Cyclophosphamide results in increased expression of HSPB1 mRNA 		CTD PMID:11599041 PMID:11906922 PMID:18246545 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSPD1 mRNA CTD PMID:11906922 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSPE1 mRNA CTD PMID:11906922 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of HSPH1 mRNA CTD PMID:24356939 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO Cyclophosphamide metabolite results in decreased expression of HYLS1 mRNA CTD PMID:24356939 NCBI chr 8:42,170,505...42,179,573
Ensembl chr 8:42,168,546...42,179,725 		JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression EXP Cyclophosphamide results in decreased expression of HYOU1 mRNA CTD PMID:11906922 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997 		JBrowse link
G Ica1 islet cell autoantigen 1 affects response to substance ISO ICA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:11751995 NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:37,622,759...37,770,569 		JBrowse link
G Icam1 intercellular adhesion molecule 1 affects response to substance
multiple interactions 		ISO ICAM1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of ICAM1 mRNA] 		CTD PMID:11591119 PMID:36031164 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ID2 mRNA CTD PMID:24356939 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of IDI1 mRNA CTD PMID:24356939 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of IDO1 protein
Cyclophosphamide results in increased expression of and results in increased activity of IDO1 protein; Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of IDO1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of and results in increased activity of IDO1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IDO1 protein] 		CTD PMID:34748891 PMID:35906875 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of IER3 mRNA CTD PMID:24356939 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Ier5 immediate early response 5 increases expression ISO Cyclophosphamide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:69,820,451...69,822,543 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Cyclophosphamide results in increased expression of IFIT2 mRNA CTD PMID:15331540 NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798 		JBrowse link
G Ifna1 interferon, alpha 1 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of IFNA1 mRNA
naringin inhibits the reaction [Cyclophosphamide results in increased expression of IFNA1 mRNA] 		CTD PMID:33992719 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Ifng interferon gamma affects expression
multiple interactions
decreases secretion
increases expression
decreases expression 		ISO
EXP 		Cyclophosphamide affects the expression of IFNG mRNA
Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IFNG protein]
[Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA
Cyclophosphamide results in decreased secretion of IFNG protein
Cyclophosphamide results in increased expression of IFNG mRNA
Cyclophosphamide results in decreased expression of IFNG mRNA; Cyclophosphamide results in decreased expression of IFNG protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG protein]; IFNG protein inhibits the reaction [Cyclophosphamide results in increased abundance of Nitric Oxide]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein] 		CTD PMID:10607705 PMID:11006010 PMID:11014644 PMID:15331540 PMID:18848347 More... NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifngr1 interferon gamma receptor 1 decreases expression ISO Cyclophosphamide results in decreased expression of IFNGR1 mRNA CTD PMID:21041162 NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of IFRD1 mRNA CTD PMID:24356939 NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of IGF1 protein CTD PMID:39079574 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 affects response to substance ISO IGF2BP3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 affects response to substance
decreases expression 		ISO
EXP 		IGFBP3 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of IGFBP3 protein
Cyclophosphamide results in decreased expression of IGFBP3 mRNA 		CTD PMID:16141653 PMID:16217747 PMID:39079574 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Cyclophosphamide results in decreased expression of IGFBP5 mRNA CTD PMID:15331540 PMID:20849824 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 multiple interactions
decreases expression 		ISO ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IGHG1 protein] CTD PMID:37853057
G Igkc immunoglobulin kappa constant decreases expression ISO Cyclophosphamide results in decreased expression of IGKC mRNA CTD PMID:15331540
G Il10 interleukin 10 decreases expression
multiple interactions
increases expression 		ISO
EXP 		Cyclophosphamide results in decreased expression of IL10 mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL10 protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; Berberine inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]
Cyclophosphamide results in increased expression of IL10 mRNA 		CTD PMID:11014644 PMID:11948286 PMID:18848347 PMID:21068404 PMID:25451569 More... NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12a interleukin 12A multiple interactions
decreases expression 		ISO [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL12A protein] CTD PMID:29228376 PMID:37853057 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B affects expression
decreases expression
multiple interactions
increases expression 		ISO Cyclophosphamide affects the expression of IL12B mRNA
Cyclophosphamide results in decreased expression of IL12B protein
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]
[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL12B protein]
Cyclophosphamide results in increased expression of IL12B mRNA 		CTD PMID:15331540 PMID:18957084 PMID:22842586 PMID:29228376 PMID:36416909 More... NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 increases expression ISO Cyclophosphamide results in increased expression of IL13RA1 mRNA CTD PMID:21041162 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il15 interleukin 15 multiple interactions
decreases secretion 		ISO (4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein] CTD PMID:23395935 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases expression ISO Cyclophosphamide results in increased expression of IL15RA mRNA CTD PMID:21041162 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149 		JBrowse link
G Il16 interleukin 16 decreases expression ISO Cyclophosphamide results in decreased expression of IL16 mRNA CTD PMID:21041162 NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023 		JBrowse link
G Il17a interleukin 17A decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of IL17A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein] 		CTD PMID:21880982 PMID:32151603 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 increases expression EXP Cyclophosphamide results in increased expression of IL18 protein CTD PMID:18848347 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
affects response to substance 		ISO
EXP 		Cyclophosphamide results in increased expression of IL1A mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein
Cyclophosphamide results in increased expression of IL1A protein
IL1A promoter polymorphism affects the susceptibility to Cyclophosphamide 		CTD PMID:15331540 PMID:16636934 PMID:18848347 PMID:31651976 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta increases expression
increases expression
increases secretion
decreases expression
increases response to substance
multiple interactions 		ISO
EXP 		Cyclophosphamide results in increased expression of IL1B mRNA; Cyclophosphamide results in increased expression of IL1B protein
[doxorubicin cotreated with cyclophosphamide] increased expression of Il1b protein in prefrontal cortex and hippocampus
Cyclophosphamide results in increased secretion of IL1B protein
Cyclophosphamide results in decreased expression of IL1B protein
IL1B protein results in increased susceptibility to Cyclophosphamide
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1B protein; [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL1B protein; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; levocabastine inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of IL1B protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; naringin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein] 		CTD
RGD		 PMID:8634684 PMID:11948286 PMID:15331540 PMID:18206168 PMID:18483878 More... RGD:597621662 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of IL1R1 mRNA
naringin inhibits the reaction [Cyclophosphamide results in increased expression of IL1R1 mRNA] 		CTD PMID:33992719 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO Cyclophosphamide results in increased expression of IL1RN mRNA CTD PMID:15331540 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il2 interleukin 2 increases expression
decreases expression
decreases secretion
multiple interactions 		ISO
EXP 		Cyclophosphamide results in increased expression of IL2 mRNA
Cyclophosphamide results in decreased expression of IL2 mRNA
Cyclophosphamide results in decreased secretion of IL2 protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]
Cyclophosphamide results in decreased expression of IL2 protein 		CTD PMID:11006010 PMID:11948286 PMID:18848347 PMID:23395935 PMID:32151603 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il21 interleukin 21 multiple interactions
decreases expression 		ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein] CTD PMID:32151603 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il23a interleukin 23 subunit alpha decreases secretion
decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased secretion of IL23A protein
Cyclophosphamide results in decreased expression of IL23A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL23A protein] 		CTD PMID:23395935 PMID:32151603 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il3 interleukin 3 multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL3 protein CTD PMID:31651976 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
increases expression 		ISO
EXP 		Cyclophosphamide results in decreased expression of IL4 mRNA; Cyclophosphamide results in decreased expression of IL4 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]
Cyclophosphamide results in increased expression of IL4 mRNA; Cyclophosphamide results in increased expression of IL4 protein 		CTD PMID:11006010 PMID:11014644 PMID:11948286 PMID:18848347 PMID:22842586 More... NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 increases expression ISO
EXP 		Cyclophosphamide results in increased expression of IL5 mRNA; Cyclophosphamide results in increased expression of IL5 protein CTD PMID:11006010 PMID:18848347 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
decreases secretion 		ISO
EXP 		[Cyclophosphamide co-treated with Dexamethasone] inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]; [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL6 protein; Donepezil inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL6 protein]; levocabastine inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 mRNA]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 protein]
Cyclophosphamide results in increased secretion of IL6 protein
Cyclophosphamide results in increased expression of IL6 mRNA; Cyclophosphamide results in increased expression of IL6 protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of IL6 protein]; Berberine inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Silymarin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein] 		CTD PMID:10052129 PMID:11948286 PMID:17010015 PMID:18848347 PMID:20126887 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ILF3 mRNA CTD PMID:16322899 NCBI chr 8:28,198,454...28,236,634
Ensembl chr 8:28,198,543...28,236,612 		JBrowse link
G Irag2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression ISO Cyclophosphamide results in decreased expression of IRAG2 mRNA CTD PMID:21041162 NCBI chr 4:179,819,526...179,874,408
Ensembl chr 4:179,820,188...179,874,406 		JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression ISO Cyclophosphamide results in decreased expression of IREB2 protein CTD PMID:32129080 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of IRS1 mRNA CTD PMID:16322899 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Cyclophosphamide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656 		JBrowse link
G Isl2 ISL LIM homeobox 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ISL2 mRNA CTD PMID:24356939 NCBI chr 8:64,819,879...64,824,864
Ensembl chr 8:64,819,879...64,824,864 		JBrowse link
G Itk IL2-inducible T-cell kinase decreases expression ISO Cyclophosphamide results in decreased expression of ITK mRNA CTD PMID:21041162 NCBI chr10:31,254,667...31,316,004
Ensembl chr10:31,254,667...31,316,004 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 multiple interactions
decreases expression 		ISO PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of JAG1 protein]; SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of JAG1 protein]; Valproic Acid inhibits the reaction [Cyclophosphamide results in decreased expression of JAG1 protein] CTD PMID:34658283 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO Cyclophosphamide results in decreased expression of JCHAIN mRNA CTD PMID:15331540 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,822,976...19,838,307 		JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 decreases expression ISO Cyclophosphamide results in decreased expression of KBTBD11 mRNA CTD PMID:17403535 NCBI chr16:74,618,291...74,638,010
Ensembl chr16:81,313,093...81,340,390 		JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 decreases expression ISO Cyclophosphamide results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:139,560,366...139,612,102 		JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions
increases expression 		ISO Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in increased expression of KDM1A protein 		CTD PMID:22007908 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:154,065,543...154,121,775 		JBrowse link
G Kdm2a lysine demethylase 2A increases expression EXP Cyclophosphamide results in increased expression of KDM2A mRNA CTD PMID:27281708 NCBI chr 1:211,041,859...211,125,749
Ensembl chr 1:211,041,885...211,084,479 		JBrowse link
G Kdm4b lysine demethylase 4B multiple interactions ISO KDM4B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:1,245,885...1,324,384
Ensembl chr 9:1,245,899...1,324,384 		JBrowse link
G Kdr kinase insert domain receptor decreases expression
increases expression 		EXP Cyclophosphamide results in decreased expression of KDR mRNA; Cyclophosphamide results in decreased expression of KDR protein
Cyclophosphamide results in increased expression of KDR mRNA 		CTD PMID:18632792 PMID:19701751 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
decreases expression 		EXP Quercetin inhibits the reaction [Cyclophosphamide results in decreased expression of KEAP1 mRNA] CTD PMID:37419146 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Kif21b kinesin family member 21B decreases expression ISO Cyclophosphamide metabolite results in decreased expression of KIF21B mRNA CTD PMID:24356939 NCBI chr13:50,127,842...50,177,822
Ensembl chr13:50,127,842...50,177,822 		JBrowse link
G Kif3a kinesin family member 3a multiple interactions ISO KIF3A mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:38,226,388...38,263,062
Ensembl chr10:38,226,741...38,260,516 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of KIT protein
[dorsomorphin co-treated with Cyclophosphamide] results in decreased expression of KIT protein; asperuloside inhibits the reaction [[dorsomorphin co-treated with Cyclophosphamide] results in decreased expression of KIT protein]; asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of KIT protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in decreased expression of KIT protein] 		CTD PMID:38348709 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Kitlg KIT ligand affects expression
increases expression
multiple interactions 		ISO Cyclophosphamide affects the expression of KITL mRNA
Cyclophosphamide results in increased expression of KITL mRNA
[Cyclophosphamide co-treated with Sizofiran] results in increased expression of KITL mRNA 		CTD PMID:10052129 PMID:12624490 PMID:12662436 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793 		JBrowse link
G Klf13 KLF transcription factor 13 decreases expression ISO Cyclophosphamide results in decreased expression of KLF13 mRNA CTD PMID:21041162 NCBI chr 1:117,505,857...117,536,626
Ensembl chr 1:126,916,781...126,961,056 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression ISO Cyclophosphamide results in increased expression of KLF2 mRNA CTD PMID:21041162 NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768 		JBrowse link
G Klf4 KLF transcription factor 4 decreases response to substance ISO KLF4 results in decreased susceptibility to Cyclophosphamide CTD PMID:21833590 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Klf5 KLF transcription factor 5 affects response to substance ISO KLF5 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262 		JBrowse link
G Krcc1 lysine-rich coiled-coil 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of KRCC1 mRNA CTD PMID:24356939 NCBI chr 4:104,819,958...104,832,987
Ensembl chr 4:104,819,190...104,855,484 		JBrowse link
G Krt8 keratin 8 decreases expression ISO Cyclophosphamide results in decreased expression of KRT8 mRNA CTD PMID:21621594 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403 		JBrowse link
G Krt80 keratin 80 increases expression ISO Cyclophosphamide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:134,341,956...134,364,211 		JBrowse link
G Lama5 laminin subunit alpha 5 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of LAMA5 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of LAMA5 mRNA] 		CTD PMID:30760223 NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173 		JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Cyclophosphamide results in increased expression of LAMC2 mRNA CTD PMID:21527772 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102 		JBrowse link
G Lasp1 LIM and SH3 protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of LASP1 mRNA CTD PMID:27281708 NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988 		JBrowse link
G Lat linker for activation of T cells decreases expression ISO Cyclophosphamide results in decreased expression of LAT mRNA CTD PMID:21041162 NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:190,367,109...190,372,153 		JBrowse link
G Lats1 large tumor suppressor kinase 1 multiple interactions EXP Cyclophosphamide results in decreased expression of and results in increased phosphorylation of LATS1 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of and results in increased phosphorylation of LATS1 protein] CTD PMID:36154502 NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:3,980,544...4,014,029 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO Cyclophosphamide results in decreased expression of LCK mRNA CTD PMID:21041162 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267 		JBrowse link
G Lcn2 lipocalin 2 increases expression
multiple interactions 		ISO
EXP 		Cyclophosphamide results in increased expression of LCN2 mRNA
herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of LCN2 protein]
Cyclophosphamide results in increased expression of LCN2 mRNA; Cyclophosphamide results in increased expression of LCN2 protein
[Cyclophosphamide co-treated with Mecamylamine] results in increased expression of LCN2 mRNA 		CTD PMID:15331540 PMID:18433785 PMID:20623750 PMID:36198566 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Ldhb lactate dehydrogenase B affects response to substance ISO LDHB protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of LEF1 mRNA CTD PMID:21041162 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Lgals1 galectin 1 increases expression ISO Cyclophosphamide results in increased expression of LGALS1 mRNA CTD PMID:17403535 NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800 		JBrowse link
G Lgals7 galectin 7 increases expression ISO Cyclophosphamide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:93,273,836...93,279,528 		JBrowse link
G Lhb luteinizing hormone subunit beta decreases secretion
increases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide results in decreased secretion of LHB protein
Cyclophosphamide results in increased expression of LHB protein
Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of LHB protein]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of LHB protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein] 		CTD PMID:25446862 PMID:32197949 PMID:32456565 PMID:36154502 PMID:39952379 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lhx2 LIM homeobox 2 decreases expression EXP Cyclophosphamide results in decreased expression of LHX2 mRNA CTD PMID:27281708 NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645 		JBrowse link
G Limd1 LIM domain containing 1 increases expression EXP Cyclophosphamide results in increased expression of LIMD1 mRNA CTD PMID:27281708 NCBI chr 8:131,998,262...132,045,924
Ensembl chr 8:131,999,770...132,045,922 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Cyclophosphamide results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875 		JBrowse link
G Lmnb1 lamin B1 multiple interactions ISO [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of LMNB1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of LMNB1 protein CTD PMID:15582267 NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283 		JBrowse link
G Lonrf2 LON peptidase N-terminal domain and ring finger 2 increases expression EXP Cyclophosphamide results in increased expression of LONRF2 mRNA CTD PMID:27281708 NCBI chr 9:41,033,125...41,070,551
Ensembl chr 9:48,530,549...48,570,807 		JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 decreases expression ISO Cyclophosphamide results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr11:70,132,919...70,168,526
Ensembl chr11:83,648,772...83,673,878 		JBrowse link
G Ltbr lymphotoxin beta receptor increases expression ISO Cyclophosphamide results in increased expression of LTBR mRNA CTD PMID:21041162 NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296 		JBrowse link
G Ltf lactotransferrin decreases expression ISO Cyclophosphamide results in decreased expression of LTF mRNA CTD PMID:21621594 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:119,878,344...119,901,189 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression ISO Cyclophosphamide results in increased expression of LY6A mRNA CTD PMID:15331540 PMID:21041162 NCBI chr 7:107,177,191...107,189,436 JBrowse link
G Maged1 MAGE family member D1 affects response to substance ISO MAGED1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr  X:63,416,464...63,423,167
Ensembl chr  X:63,416,466...63,423,112 		JBrowse link
G Man2b2 mannosidase, alpha, class 2B, member 2 decreases expression EXP Cyclophosphamide results in decreased expression of MAN2B2 mRNA CTD PMID:27281708 NCBI chr14:73,969,079...73,994,089
Ensembl chr14:78,193,725...78,227,724 		JBrowse link
G Maoa monoamine oxidase A increases expression ISO Cyclophosphamide results in increased expression of MAOA mRNA CTD PMID:17403535 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation 		ISO asperuloside promotes the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein]; CSF2 protein promotes the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein]; dorsomorphin inhibits the reaction [asperuloside promotes the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein]]; dorsomorphin inhibits the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein] CTD PMID:38348709 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 affects expression EXP Cyclophosphamide affects the expression of MAP3K12 mRNA CTD PMID:18246545 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:135,508,790...135,515,137 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
increases expression 		ISO
EXP 		Cyclophosphamide results in increased phosphorylation of MAPK1 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Cyclophosphamide results in increased expression of MAPK1 mRNA; Cyclophosphamide results in increased expression of MAPK1 protein modified form 		CTD PMID:11599041 PMID:15733095 PMID:17110531 PMID:17409261 PMID:19638304 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases expression
decreases expression
affects expression 		ISO
EXP 		[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA
Cyclophosphamide results in increased expression of MAPK14 protein
chrysin inhibits the reaction [Cyclophosphamide results in increased expression of MAPK14 protein]
Cyclophosphamide results in decreased expression of MAPK14 mRNA
Cyclophosphamide affects the expression of MAPK14 mRNA 		CTD PMID:16322899 PMID:18246545 PMID:37263553 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
multiple interactions
increases phosphorylation 		EXP
ISO 		Cyclophosphamide results in increased expression of MAPK3 protein modified form
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Cyclophosphamide results in increased phosphorylation of MAPK3 protein 		CTD PMID:15733095 PMID:17110531 PMID:17409261 PMID:19638304 PMID:19696094 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK7 protein CTD PMID:17110531 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions 		ISO
EXP 		Cyclophosphamide results in increased phosphorylation of MAPK8 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]; Mesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]] 		CTD PMID:19696094 PMID:19996110 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:19996110 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 decreases expression EXP Cyclophosphamide results in decreased expression of MARCHF7 mRNA CTD PMID:27281708 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:65,090,310...65,128,864 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression ISO Cyclophosphamide results in increased expression of MARCKS mRNA CTD PMID:17403535 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Cyclophosphamide results in decreased expression of MCM5 mRNA CTD PMID:21041162 NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758 		JBrowse link
G Mdfic MyoD family inhibitor domain containing decreases expression ISO Cyclophosphamide results in decreased expression of MDFIC mRNA CTD PMID:17403535 NCBI chr 4:44,938,301...45,018,157
Ensembl chr 4:44,938,480...45,018,156 		JBrowse link
G Med13l mediator complex subunit 13L multiple interactions ISO MED13L mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:43,468,556...43,665,819
Ensembl chr12:43,468,556...43,665,819 		JBrowse link
G Melk maternal embryonic leucine zipper kinase multiple interactions ISO MELK mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247 		JBrowse link
G Metrn meteorin, glial cell differentiation regulator multiple interactions ISO METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:15,321,200...15,323,218
Ensembl chr10:15,321,200...15,323,642 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression ISO Cyclophosphamide results in decreased expression of MFGE8 mRNA CTD PMID:15331540 NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression
decreases response to substance 		ISO Cyclophosphamide results in decreased expression of MGMT mRNA
MGMT protein results in decreased susceptibility to Cyclophosphamide 		CTD PMID:15741301 PMID:17403535 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression EXP Cyclophosphamide results in decreased expression of MGST1 mRNA CTD PMID:11906922 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875 		JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions EXP Cyclophosphamide affects the localization of and affects the expression of MIF protein; Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein] CTD PMID:19066630 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression
increases expression
multiple interactions 		ISO
EXP 		Cyclophosphamide results in decreased expression of MKI67 protein
Cyclophosphamide results in increased expression of MKI67 protein
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of MKI67 protein]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of MKI67 protein] 		CTD PMID:33737021 PMID:36154502 PMID:39209270 PMID:39952379 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mlh1 mutL homolog 1 decreases expression EXP Cyclophosphamide results in decreased expression of MLH1 mRNA CTD PMID:11906922 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor decreases response to substance ISO MLLT11 protein results in decreased susceptibility to Cyclophosphamide CTD PMID:31587870 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:185,484,793...185,493,961 		JBrowse link
G Mmel1 membrane metallo-endopeptidase-like 1 increases expression EXP Cyclophosphamide results in increased expression of MMEL1 mRNA CTD PMID:27281708 NCBI chr 5:170,713,602...170,744,058
Ensembl chr 5:170,713,627...170,744,058 		JBrowse link
G Mmp11 matrix metallopeptidase 11 decreases expression EXP Cyclophosphamide results in decreased expression of MMP11 mRNA CTD PMID:27281708 NCBI chr20:12,730,284...12,739,067
Ensembl chr20:12,730,277...12,739,290 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Cyclophosphamide results in increased expression of MMP3 mRNA CTD PMID:15331540 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp8 matrix metallopeptidase 8 increases expression EXP Cyclophosphamide results in increased expression of MMP8 mRNA CTD PMID:27281708 NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen increases expression ISO Cyclophosphamide results in increased expression of IFI204 mRNA CTD PMID:21041162 NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 affects response to substance ISO MPC2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:80,261,143...80,280,668
Ensembl chr13:80,259,727...80,280,668 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase affects expression EXP Cyclophosphamide affects the expression of MPG mRNA CTD PMID:11906922 NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity 		EXP
ISO 		Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Hemin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]
fosaprepitant inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] 		CTD PMID:10749792 PMID:17979934 PMID:18710439 PMID:25451569 PMID:34748891 More... NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression ISO Cyclophosphamide results in increased expression of MR1 mRNA CTD PMID:21527772 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502 		JBrowse link
G Ms4a3 membrane spanning 4-domains A3 decreases expression ISO Cyclophosphamide results in decreased expression of MS4A3 mRNA CTD PMID:17403535 NCBI chr 1:208,462,300...208,480,129
Ensembl chr 1:217,887,105...217,904,907 		JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Cyclophosphamide results in decreased expression of MSH2 mRNA CTD PMID:11056294 PMID:11906922 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Msh3 mutS homolog 3 decreases expression EXP Cyclophosphamide results in decreased expression of MSH3 mRNA CTD PMID:11906922 NCBI chr 2:25,179,400...25,320,857
Ensembl chr 2:25,179,400...25,321,102 		JBrowse link
G Mss51 MSS51 mitochondrial translational activator increases expression EXP Cyclophosphamide results in increased expression of MSS51 mRNA CTD PMID:27281708 NCBI chr15:3,805,240...3,819,385
Ensembl chr15:3,855,478...3,868,611 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Cyclophosphamide metabolite results in decreased expression of MTHFD2 mRNA CTD PMID:24356939 NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation 		ISO asperuloside inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]; asperuloside inhibits the reaction [dorsomorphin promotes the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]]; CSF2 protein inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]; dorsomorphin promotes the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein] CTD PMID:38348709 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases expression EXP Cyclophosphamide results in decreased expression of MTR mRNA CTD PMID:27281708 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541 		JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO Cyclophosphamide results in increased expression of MUC13 mRNA CTD PMID:15331540 NCBI chr11:66,957,208...66,980,264
Ensembl chr11:80,465,737...80,485,474 		JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO Cyclophosphamide results in decreased expression of MX2 mRNA CTD PMID:17403535 NCBI chr11:50,375,101...50,399,373
Ensembl chr11:50,375,191...50,402,478 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein affects response to substance ISO MXI1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:262,328,875...262,389,036 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [fosaprepitant co-treated with Cyclophosphamide] results in decreased expression of MYD88 protein CTD PMID:39378958 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Myh10 myosin heavy chain 10 affects response to substance ISO MYH10 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of NAIP mRNA CTD PMID:16322899 NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:33,241,521...33,276,859 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Cyclophosphamide results in increased expression of NAMPT mRNA CTD PMID:21041162 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of NANOS1 mRNA CTD PMID:24356939 NCBI chr 1:269,883,713...269,887,611
Ensembl chr 1:269,883,536...269,895,417 		JBrowse link
G Nasp nuclear autoantigenic sperm protein increases expression EXP Cyclophosphamide results in increased expression of NASP mRNA CTD PMID:16141653 NCBI chr 5:135,294,599...135,319,992
Ensembl chr 5:135,294,032...135,319,591 		JBrowse link
G Ncoa7 nuclear receptor coactivator 7 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of NCOA7 mRNA CTD PMID:24356939 NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:28,675,426...28,835,886 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Cyclophosphamide results in decreased expression of NDUFS2 mRNA CTD PMID:15331540 NCBI chr13:86,186,867...86,203,914
Ensembl chr13:86,186,870...86,203,608 		JBrowse link
G Neto2 neuropilin and tolloid like 2 increases expression ISO Cyclophosphamide results in increased expression of NETO2 mRNA CTD PMID:21527772 NCBI chr19:37,517,518...37,588,961
Ensembl chr19:37,517,587...37,591,413 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 decreases expression ISO Cyclophosphamide results in decreased expression of NFATC3 mRNA CTD PMID:21041162 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
increases response to substance
increases expression 		EXP
ISO 		[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; [Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 mRNA]; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of NFE2L2 mRNA]
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
NFE2L2 gene mutant form results in increased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of NFE2L2 mRNA; Cyclophosphamide results in increased expression of NFE2L2 protein
Cyclophosphamide results in decreased expression of NFE2L2 mRNA; Cyclophosphamide results in decreased expression of NFE2L2 protein 		CTD PMID:20038455 PMID:20433640 PMID:27633142 PMID:32129080 PMID:32456565 More... NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfe2l3 NFE2 like bZIP transcription factor 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of NFE2L3 mRNA CTD PMID:24356939 NCBI chr 4:81,837,404...81,865,258
Ensembl chr 4:81,837,404...81,865,532 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions 		ISO Cyclophosphamide results in increased phosphorylation of NFKBIA protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of NFKBIA protein] 		CTD PMID:30506662 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Cyclophosphamide results in increased expression of NFKBIZ mRNA CTD PMID:15331540 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
decreases expression 		ISO
EXP 		3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]; VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]
NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]
Cyclophosphamide results in increased expression of NGF mRNA; Cyclophosphamide results in increased expression of NGF protein
Cyclophosphamide results in decreased expression of NGF protein 		CTD PMID:10683293 PMID:16879691 PMID:18299998 PMID:18632792 PMID:19996110 More... NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Ngfr nerve growth factor receptor increases expression EXP Cyclophosphamide results in increased expression of NGFR mRNA; Cyclophosphamide results in increased expression of NGFR protein CTD PMID:8817519 PMID:18189308 PMID:18842820 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305 		JBrowse link
G Nid1 nidogen 1 affects response to substance ISO NID1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr17:93,069,013...93,142,416
Ensembl chr17:93,069,278...93,142,386 		JBrowse link
G Nkain1 Sodium/potassium transporting ATPase interacting 1 multiple interactions ISO NKAIN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:142,747,702...142,792,665
Ensembl chr 5:148,031,338...148,076,834 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression 		EXP
ISO 		Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]
Donepezil inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]; levocabastine inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] 		CTD PMID:35762198 PMID:38278497 PMID:38825044 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression EXP Cyclophosphamide results in increased expression of NME1 mRNA CTD PMID:11599041 NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310 		JBrowse link
G Nos1 nitric oxide synthase 1 increases expression
multiple interactions
decreases expression 		EXP Cyclophosphamide results in increased expression of NOS1 protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in decreased expression of NOS1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of NOS1 protein] 		CTD PMID:31779506 PMID:35906875 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
increases expression
increases activity 		EXP
ISO 		allyl sulfide inhibits the reaction [Cyclophosphamide results in decreased expression of NOS2 protein]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; ginkgolide B inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; pimagedine inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Cyclophosphamide results in increased expression of NOS2 mRNA; Cyclophosphamide results in increased expression of NOS2 protein 		CTD PMID:9006340 PMID:10607705 PMID:11046124 PMID:15821589 PMID:16879691 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 decreases activity
decreases expression
multiple interactions
increases expression 		EXP Cyclophosphamide results in decreased activity of NOS3 protein
Cyclophosphamide results in decreased expression of NOS3 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in decreased expression of NOS3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in decreased expression of NOS3 protein]
Cyclophosphamide results in increased expression of NOS3 protein 		CTD PMID:9006340 PMID:16125470 PMID:35762198 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Notch1 notch receptor 1 multiple interactions
decreases expression 		ISO PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of NOTCH1 protein]; SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of NOTCH1 protein]; Valproic Acid inhibits the reaction [Cyclophosphamide results in decreased expression of NOTCH1 protein] CTD PMID:34658283 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613 		JBrowse link
G Nppb natriuretic peptide B increases expression ISO Cyclophosphamide results in increased expression of NPPB protein CTD PMID:17562616 PMID:18548196 PMID:18999883 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit decreases expression ISO Cyclophosphamide results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 8:117,094,443...117,097,639
Ensembl chr 8:117,094,441...117,097,637 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
increases expression 		EXP
ISO 		Cyclophosphamide results in decreased expression of NQO1 mRNA; Cyclophosphamide results in decreased expression of NQO1 protein
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in decreased expression of NQO1 mRNA]
Cyclophosphamide results in increased expression of NQO1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein] 		CTD PMID:11906922 PMID:20038455 PMID:20433640 PMID:21041162 PMID:27633142 More... NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP Cyclophosphamide results in decreased expression of NR1H4 mRNA CTD PMID:28391356 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions 		ISO Cyclophosphamide results in increased activity of NR1I2 protein
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Cyclophosphamide binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein] 		CTD PMID:17041008 PMID:18839173 PMID:20041327 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 increases expression EXP Cyclophosphamide results in increased expression of NR2C2 mRNA CTD PMID:27281708 NCBI chr 4:124,610,216...124,666,813
Ensembl chr 4:126,168,085...126,223,942 		JBrowse link
G Nrap nebulin-related anchoring protein increases expression EXP Cyclophosphamide results in increased expression of NRAP mRNA CTD PMID:27281708 NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:265,355,327...265,432,950 		JBrowse link
G Nrdc nardilysin convertase decreases expression EXP Cyclophosphamide results in decreased expression of NRDC mRNA CTD PMID:27281708 NCBI chr 5:128,983,395...129,047,578
Ensembl chr 5:128,984,446...129,050,141 		JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Cyclophosphamide results in increased expression of NRG1 mRNA CTD PMID:21527772 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Nrp1 neuropilin 1 decreases expression
increases expression 		ISO
EXP 		Cyclophosphamide results in decreased expression of NRP1 mRNA
Cyclophosphamide results in increased expression of NRP1 mRNA 		CTD PMID:15331540 PMID:18632792 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Nrp2 neuropilin 2 increases expression EXP Cyclophosphamide results in increased expression of NRP2 mRNA CTD PMID:18632792 NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO Cyclophosphamide results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr 1:255,712,797...255,838,285
Ensembl chr 1:255,713,909...255,838,403 		JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Cyclophosphamide results in increased expression of NTF3 mRNA CTD PMID:10683293 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Ntf4 neurotrophin 4 increases expression EXP Cyclophosphamide results in increased expression of NTF4 mRNA CTD PMID:10683293 NCBI chr 1:105,030,035...105,032,866
Ensembl chr 1:105,029,764...105,034,038 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK1 protein CTD PMID:12412144 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK2 protein CTD PMID:12412144 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628 		JBrowse link
G Nup42 nucleoporin 42 increases expression EXP Cyclophosphamide results in increased expression of NUP42 mRNA CTD PMID:27281708 NCBI chr 4:11,877,957...11,894,991
Ensembl chr 4:11,877,957...11,894,991 		JBrowse link
G Ocln occludin decreases expression
increases expression
multiple interactions 		ISO
EXP 		Cyclophosphamide results in decreased expression of OCLN protein
Cyclophosphamide results in increased expression of OCLN protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of OCLN protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of OCLN protein] 		CTD PMID:32151603 PMID:32615180 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP Cyclophosphamide results in increased expression of ODC1 mRNA CTD PMID:11599041 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Cyclophosphamide results in decreased expression of OGG1 protein CTD PMID:27032448 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604 		JBrowse link
G Opn3 opsin 3 affects response to substance ISO OPN3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:90,121,560...90,152,076
Ensembl chr13:90,121,560...90,152,076 		JBrowse link
G Osm oncostatin M affects expression ISO Cyclophosphamide affects the expression of OSM mRNA CTD PMID:12624490 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G P2rx3 purinergic receptor P2X 3 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of P2RX3 protein
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein] 		CTD PMID:23666265 NCBI chr 3:90,487,506...90,531,315
Ensembl chr 3:90,487,506...90,531,794 		JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases expression ISO Cyclophosphamide results in decreased expression of P2RY2 mRNA CTD PMID:17403535 NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:164,759,213...164,781,852 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr 2:53,255,916...53,282,965
Ensembl chr 2:53,237,924...53,282,966 		JBrowse link
G Pakap paralemmin A kinase anchor protein increases expression ISO Cyclophosphamide results in increased expression of PALM2AKAP2 mRNA CTD PMID:17403535 NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656 		JBrowse link
G Pard3 par-3 family cell polarity regulator decreases expression ISO Cyclophosphamide results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
increases cleavage
decreases expression 		ISO
EXP 		[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein
Cyclophosphamide results in increased expression of PARP1 protein
chrysin inhibits the reaction [Cyclophosphamide results in increased expression of PARP1 protein]
Cyclophosphamide results in increased expression of PARP1 mRNA; Cyclophosphamide results in increased expression of PARP1 protein
Cyclophosphamide results in increased cleavage of PARP1 protein
Cyclophosphamide results in decreased expression of PARP1 mRNA 		CTD PMID:11599041 PMID:11723234 PMID:11906922 PMID:15582267 PMID:17898787 More... NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pax5 paired box 5 increases expression
multiple interactions
decreases methylation 		ISO Cyclophosphamide results in increased expression of PAX5 protein
Cyclophosphamide promotes the reaction [SGI-1027 results in increased expression of PAX5 protein]; PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of HES5 protein]; PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of JAG1 protein]; PAX5 protein affects the reaction [Cyclophosphamide results in decreased expression of NOTCH1 protein]; PAX5 protein affects the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; SGI-1027 promotes the reaction [Cyclophosphamide results in decreased methylation of PAX5 gene]; SGI-1027 promotes the reaction [Cyclophosphamide results in increased expression of PAX5 protein] 		CTD PMID:34658283 NCBI chr 5:63,554,784...63,741,380
Ensembl chr 5:63,560,722...63,739,987 		JBrowse link
G Pcna proliferating cell nuclear antigen affects expression
multiple interactions
decreases expression
increases expression 		EXP
ISO 		Cyclophosphamide affects the expression of PCNA mRNA
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of PCNA mRNA]
Cyclophosphamide results in decreased expression of PCNA protein
Cyclophosphamide results in increased expression of PCNA mRNA 		CTD PMID:11056294 PMID:18246545 PMID:19701751 PMID:21041162 PMID:31557371 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 decreases expression ISO Cyclophosphamide results in decreased expression of PCSK2 mRNA CTD PMID:15331540 NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Cyclophosphamide results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP Cyclophosphamide results in decreased expression of PDIA3 mRNA CTD PMID:11906922 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP Cyclophosphamide results in increased expression of PDIA4 mRNA CTD PMID:11599041 NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP Cyclophosphamide results in increased expression of PEBP1 protein CTD PMID:15928459 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of PELI1 mRNA CTD PMID:24356939 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466 		JBrowse link
G Per1 period circadian regulator 1 multiple interactions
decreases expression 		ISO 5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of PER1 mRNA] CTD PMID:30760223 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 increases expression ISO Cyclophosphamide results in increased expression of PHLDA2 mRNA CTD PMID:17403535 NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis EXP Cyclophosphamide results in increased mutagenesis of PIGA CTD PMID:22923490 NCBI chr  X:33,672,832...33,687,747
Ensembl chr  X:33,674,923...33,687,636 		JBrowse link
G Pigr polymeric immunoglobulin receptor increases expression ISO Cyclophosphamide results in increased expression of PIGR mRNA CTD PMID:15331540 NCBI chr13:44,851,001...44,879,143
Ensembl chr13:44,851,182...44,879,141 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression ISO Cyclophosphamide results in increased expression of PLA2G4A mRNA CTD PMID:21041162 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Cyclophosphamide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD1 mRNA CTD PMID:16322899 NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD3 mRNA CTD PMID:16322899 NCBI chr12:25,313,070...25,323,631
Ensembl chr12:25,313,072...25,323,631 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component increases expression EXP Cyclophosphamide results in increased expression of PMS1 mRNA CTD PMID:11056294 NCBI chr 9:55,721,393...55,832,225
Ensembl chr 9:55,745,374...55,832,221 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component decreases expression EXP Cyclophosphamide results in decreased expression of PMS2 mRNA CTD PMID:11056294 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Polm DNA polymerase mu increases expression ISO Cyclophosphamide results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr14:84,921,039...84,930,649
Ensembl chr14:84,921,045...84,930,622 		JBrowse link
G Pomc proopiomelanocortin increases expression EXP Cyclophosphamide results in increased expression of POMC protein CTD PMID:15276878 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Pon1 paraoxonase 1 increases activity EXP Cyclophosphamide results in increased activity of PON1 protein CTD PMID:17874068 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
increases expression 		ISO
EXP 		POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
Cyclophosphamide results in increased expression of POR mRNA 		CTD PMID:9766669 PMID:10919648 PMID:11599041 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Postn periostin decreases expression ISO Cyclophosphamide results in decreased expression of POSTN mRNA CTD PMID:15331540 NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of PPARA protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of PPARA protein] 		CTD PMID:29753871 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
increases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of PPARG mRNA
Cyclophosphamide results in increased expression of PPARG mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of PPARG mRNA] 		CTD PMID:25446862 PMID:27281708 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Prdm13 PR/SET domain 13 affects expression EXP Cyclophosphamide affects the expression of PRDM13 mRNA CTD PMID:27281708 NCBI chr 5:40,017,607...40,029,658
Ensembl chr 5:40,017,607...40,038,207 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions 		ISO Cyclophosphamide results in increased phosphorylation of PRKAA1 protein
asperuloside promotes the reaction [Cyclophosphamide results in increased phosphorylation of PRKAA1 protein]; CSF2 protein promotes the reaction [Cyclophosphamide results in increased phosphorylation of PRKAA1 protein] 		CTD PMID:38348709 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkcg protein kinase C, gamma decreases expression EXP Cyclophosphamide results in decreased expression of PRKCG mRNA CTD PMID:27281708 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Prlr prolactin receptor decreases expression ISO Cyclophosphamide results in decreased expression of PRLR mRNA CTD PMID:15331540 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882 		JBrowse link
G Procr protein C receptor increases expression ISO Cyclophosphamide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989 		JBrowse link
G Prss3 serine protease 3 affects response to substance ISO PRSS3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:71,169,749...71,173,223
Ensembl chr 4:71,169,749...71,173,223 		JBrowse link
G Prtn3 proteinase 3 decreases expression ISO Cyclophosphamide results in decreased expression of PRTN3 mRNA CTD PMID:17403535 NCBI chr 7:10,472,750...10,482,037
Ensembl chr 7:10,472,755...10,482,474 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression ISO Cyclophosphamide results in increased expression of PSMA5 protein CTD PMID:17475930 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:198,584,505...198,607,867 		JBrowse link
G Ptcra pre T-cell antigen receptor alpha decreases expression ISO Cyclophosphamide results in decreased expression of PTCRA mRNA CTD PMID:21041162 NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:21,716,522...21,726,751 		JBrowse link
G Ptger1 prostaglandin E receptor 1 decreases expression EXP Cyclophosphamide results in decreased expression of PTGER1 protein CTD PMID:20346049 NCBI chr19:41,374,983...41,379,593
Ensembl chr19:41,374,471...41,378,284 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions
increases expression 		EXP Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGER4 protein] CTD PMID:18514386 PMID:20346049 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Ptges3 prostaglandin E synthase 3 increases expression EXP Cyclophosphamide results in increased expression of PTGES3 mRNA CTD PMID:11599041 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO Cyclophosphamide results in increased expression of PTGS1 mRNA CTD PMID:21041162 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects response to substance
multiple interactions
increases expression 		ISO
EXP 		PTGS2 protein affects the susceptibility to Cyclophosphamide
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
Cyclophosphamide results in increased expression of PTGS2 mRNA; Cyclophosphamide results in increased expression of PTGS2 protein
Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; Silymarin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein] 		CTD PMID:12388444 PMID:15331540 PMID:16217747 PMID:17537839 PMID:18514386 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression ISO Cyclophosphamide results in increased expression of PTP4A1 mRNA CTD PMID:15331540 NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C decreases expression ISO Cyclophosphamide results in decreased expression of PTPRC mRNA CTD PMID:21041162 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Pura purine rich element binding protein A increases expression EXP Cyclophosphamide results in increased expression of PURA mRNA CTD PMID:11599041 NCBI chr18:28,159,103...28,179,539
Ensembl chr18:28,125,126...28,211,111 		JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression EXP Cyclophosphamide results in increased expression of RAD50 mRNA CTD PMID:11056294 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rad51 RAD51 recombinase decreases expression
increases expression 		ISO
EXP 		Cyclophosphamide results in decreased expression of RAD51 mRNA
Cyclophosphamide results in increased expression of RAD51 mRNA 		CTD PMID:11599041 PMID:21041162 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Rad54l RAD54 like decreases expression EXP Cyclophosphamide results in decreased expression of RAD54L mRNA CTD PMID:11056294 NCBI chr 5:134,812,158...134,841,821
Ensembl chr 5:134,811,532...134,841,425 		JBrowse link
G Rag1 recombination activating 1 decreases expression ISO Cyclophosphamide results in decreased expression of RAG1 mRNA CTD PMID:21041162 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:108,371,978...108,383,261 		JBrowse link
G Ramp1 receptor activity modifying protein 1 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of RAMP1 mRNA
RAMP1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] 		CTD PMID:16896004 PMID:17403535 NCBI chr 9:99,213,031...99,263,696 JBrowse link
G Rapsn receptor-associated protein of the synapse increases expression EXP Cyclophosphamide results in increased expression of RAPSN mRNA CTD PMID:27281708 NCBI chr 3:97,470,891...97,480,196
Ensembl chr 3:97,470,881...97,480,196 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression EXP Cyclophosphamide results in increased expression of RARA mRNA CTD PMID:16141653 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression EXP Cyclophosphamide results in decreased expression of RARG mRNA CTD PMID:27281708 NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Cyclophosphamide results in increased expression of RBPMS mRNA CTD PMID:17403535 NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 decreases expression EXP Cyclophosphamide results in decreased expression of RC3H1 mRNA CTD PMID:27281708 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 decreases expression EXP Cyclophosphamide results in decreased expression of RC3H2 mRNA CTD PMID:27281708 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:41,531,617...41,589,715 		JBrowse link
G Reg3b regenerating family member 3 beta increases expression ISO
EXP 		Cyclophosphamide results in increased expression of REG3A mRNA; Cyclophosphamide results in increased expression of REG3B mRNA
Cyclophosphamide results in increased expression of REG3B protein 		CTD PMID:15331540 PMID:18295254 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Reg3g regenerating family member 3 gamma increases expression ISO
EXP 		Cyclophosphamide results in increased expression of REG3G mRNA
Cyclophosphamide results in increased expression of REG3G protein 		CTD PMID:15331540 PMID:18295254 NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
increases expression
increases phosphorylation
increases activity
multiple interactions 		EXP
ISO 		Cyclophosphamide results in increased expression of RELA mRNA; Cyclophosphamide results in increased expression of RELA protein; Cyclophosphamide results in increased expression of RELA protein modified form
[doxorubicin cotreated with cyclophosphamide] increased expression of Rela protein in prefrontal cortex and hippocampus
Cyclophosphamide results in increased phosphorylation of RELA protein
Cyclophosphamide results in increased activity of RELA protein
Cyclophosphamide results in increased localization of and results in increased activity of RELA protein; Dexamethasone inhibits the reaction [Cyclophosphamide results in increased localization of and results in increased activity of RELA protein]; Donepezil inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein modified form]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of RELA mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein] 		CTD
RGD		 PMID:19303104 PMID:20433640 PMID:22099998 PMID:25451569 PMID:30506662 More... RGD:597621662 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rev1 REV1, DNA directed polymerase decreases response to substance ISO REV1 protein results in decreased susceptibility to Cyclophosphamide CTD PMID:21068378 NCBI chr 9:47,773,907...47,847,554
Ensembl chr 9:47,773,907...47,847,332 		JBrowse link
G Ring1 ring finger protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of RING1 mRNA CTD PMID:27281708 NCBI chr20:4,832,013...4,835,516
Ensembl chr20:4,831,993...4,835,513 		JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO Cyclophosphamide results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr11:47,118,147...47,126,244
Ensembl chr11:47,118,147...47,131,954 		JBrowse link
G Rnase2 ribonuclease A family member 2 decreases expression ISO Cyclophosphamide results in decreased expression of RNASE2 mRNA CTD PMID:17403535 NCBI chr15:24,449,618...24,450,427
Ensembl chr15:26,923,134...26,923,955 		JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Cyclophosphamide results in increased expression of RND1 mRNA CTD PMID:23558518 NCBI chr 7:131,700,321...131,707,392
Ensembl chr 7:131,700,321...131,707,392 		JBrowse link
G Rnf138l1 ring finger protein 138 like 1 increases expression EXP Cyclophosphamide results in increased expression of RNF138L1 mRNA CTD PMID:27281708 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:34,371,016...34,372,596 		JBrowse link
G Rnf180 ring finger protein 180 increases expression EXP Cyclophosphamide results in increased expression of RNF180 mRNA CTD PMID:27281708 NCBI chr 2:38,064,026...38,244,854
Ensembl chr 2:38,064,031...38,265,358 		JBrowse link
G Rnf216 ring finger protein 216 decreases expression EXP Cyclophosphamide results in decreased expression of RNF216 mRNA CTD PMID:27281708 NCBI chr12:16,568,327...16,689,868
Ensembl chr12:16,568,347...16,690,989 		JBrowse link
G Rnf44 ring finger protein 44 increases expression EXP Cyclophosphamide results in increased expression of RNF44 mRNA CTD PMID:27281708 NCBI chr17:9,919,982...9,934,376
Ensembl chr17:9,930,375...9,939,478 		JBrowse link
G Rnf5 ring finger protein 5 increases expression EXP Cyclophosphamide results in increased expression of RNF5 mRNA CTD PMID:27281708 NCBI chr20:4,145,539...4,147,985
Ensembl chr20:4,150,138...4,152,591 		JBrowse link
G Rorc RAR-related orphan receptor C decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of RORC protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of RORC protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of RORC protein] 		CTD PMID:32151603 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
G Rpa1 replication protein A1 decreases expression EXP Cyclophosphamide results in decreased expression of RPA1 mRNA CTD PMID:11906922 NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279 		JBrowse link
G Rpa2 replication protein A2 decreases expression EXP Cyclophosphamide results in decreased expression of RPA2 mRNA CTD PMID:11906922 NCBI chr 5:150,260,668...150,271,329
Ensembl chr 5:150,260,723...150,271,546 		JBrowse link
G Rps3 ribosomal protein S3 decreases expression EXP Cyclophosphamide results in decreased expression of RPS3 mRNA CTD PMID:11906922 NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 affects response to substance ISO RPS6KA2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338 		JBrowse link
G Rraga Ras-related GTP binding A decreases expression ISO Cyclophosphamide results in decreased expression of RRAGA mRNA CTD PMID:17403535 NCBI chr 5:106,159,335...106,160,930
Ensembl chr 5:106,158,853...106,160,504 		JBrowse link
G Rras2 RAS related 2 increases expression ISO Cyclophosphamide results in increased expression of RRAS2 mRNA CTD PMID:17403535 NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 decreases expression ISO Cyclophosphamide results in decreased expression of RRM1 mRNA CTD PMID:21041162 NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:166,235,900...166,260,944 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Cyclophosphamide metabolite results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Cyclophosphamide results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr20:3,407,880...3,484,130 JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 increases expression ISO Cyclophosphamide results in increased expression of RTEL1 protein CTD PMID:17475930 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Runx3 RUNX family transcription factor 3 decreases expression ISO Cyclophosphamide results in decreased expression of RUNX3 mRNA CTD PMID:20849824 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835 		JBrowse link
G S100a1 S100 calcium binding protein A1 multiple interactions
increases expression 		ISO TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of S100A1 protein] CTD PMID:39952379 NCBI chr 2:178,291,503...178,296,346
Ensembl chr 2:178,291,503...178,296,346 		JBrowse link
G S100b S100 calcium binding protein B increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of S100B protein
TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of S100B protein] 		CTD PMID:39952379 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081 		JBrowse link
G Sall1 spalt-like transcription factor 1 affects response to substance ISO SALL1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr19:34,179,316...34,196,278
Ensembl chr19:34,181,078...34,196,278 		JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO Cyclophosphamide results in decreased expression of SATB1 mRNA CTD PMID:21041162 NCBI chr 9:4,916,958...5,010,359
Ensembl chr 9:4,917,215...4,989,925 		JBrowse link
G Scg3 secretogranin III decreases expression ISO Cyclophosphamide results in decreased expression of SCG3 mRNA CTD PMID:15331540 NCBI chr 8:76,399,777...76,442,015
Ensembl chr 8:85,280,253...85,361,874 		JBrowse link
G Scrt1 scratch family transcriptional repressor 1 increases expression EXP Cyclophosphamide results in increased expression of SCRT1 mRNA CTD PMID:27281708 NCBI chr 7:110,121,640...110,125,290
Ensembl chr 7:110,121,640...110,125,290 		JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 multiple interactions ISO SCUBE2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:173,264,862...173,341,323
Ensembl chr 1:173,264,865...173,334,372 		JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component decreases expression EXP Cyclophosphamide results in decreased expression of SEC23A mRNA CTD PMID:27281708 NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:82,394,863...82,440,904 		JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP Cyclophosphamide results in increased expression of SERPINE1 mRNA CTD PMID:23558518 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sesn2 sestrin 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SESN2 mRNA CTD PMID:24356939 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255 		JBrowse link
G Sfn stratifin increases expression ISO Cyclophosphamide results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Sgce sarcoglycan, epsilon affects response to substance ISO SGCE protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:32,771,477...32,842,238
Ensembl chr 4:33,737,814...33,808,908 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SGK1 mRNA CTD PMID:24356939 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231 		JBrowse link
G Sharpin SHANK-associated RH domain interactor decreases expression EXP Cyclophosphamide results in decreased expression of SHARPIN mRNA CTD PMID:27281708 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:109,950,345...109,955,552 		JBrowse link
G Sirt3 sirtuin 3 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of SIRT3 mRNA
Carnitine inhibits the reaction [Cyclophosphamide results in increased expression of SIRT3 mRNA] 		CTD PMID:37863343 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076 		JBrowse link
G Sirt5 sirtuin 5 increases expression EXP Cyclophosphamide results in increased expression of SIRT5 mRNA CTD PMID:27281708 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,515,985...21,537,442 		JBrowse link
G Sit1 signaling threshold regulating transmembrane adaptor 1 decreases expression ISO Cyclophosphamide results in decreased expression of SIT1 mRNA CTD PMID:21041162 NCBI chr 5:62,536,003...62,538,230
Ensembl chr 5:62,536,009...62,537,911 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of SLC18A3 protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of SLC18A3 protein] 		CTD PMID:32615180 NCBI chr16:7,719,953...7,722,814 JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases expression
multiple interactions 		EXP Cyclophosphamide results in increased expression of SLC22A3 protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of SLC22A3 protein] 		CTD PMID:32615180 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions
decreases expression 		EXP Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 protein]
Cyclophosphamide results in decreased expression of SLC22A5 mRNA; Cyclophosphamide results in decreased expression of SLC22A5 protein 		CTD PMID:22701146 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression ISO Cyclophosphamide results in decreased expression of SLC2A2 mRNA CTD PMID:15331540 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467 		JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Cyclophosphamide results in increased expression of SLC2A6 mRNA CTD PMID:21527772 NCBI chr 3:30,746,472...30,753,287
Ensembl chr 3:30,745,995...30,753,287 		JBrowse link
G Slc39a13 solute carrier family 39 member 13 increases expression EXP Cyclophosphamide results in increased expression of SLC39A13 mRNA CTD PMID:27281708 NCBI chr 3:97,495,229...97,504,279
Ensembl chr 3:97,495,229...97,505,052 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression EXP Cyclophosphamide results in increased expression of SLC39A14 mRNA CTD PMID:27281708 NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229 		JBrowse link
G Slc39a5 solute carrier family 39 member 5 increases expression EXP Cyclophosphamide results in increased expression of SLC39A5 mRNA; Cyclophosphamide results in increased expression of SLC39A5 protein CTD PMID:27281708 NCBI chr 7:1,409,360...1,415,407
Ensembl chr 7:1,409,360...1,414,784 		JBrowse link
G Slc39a6 solute carrier family 39 member 6 increases expression EXP Cyclophosphamide results in increased expression of SLC39A6 mRNA CTD PMID:27281708 NCBI chr18:16,139,621...16,160,163
Ensembl chr18:16,135,008...16,160,163 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SLC3A2 mRNA CTD PMID:24356939 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of SLC40A1 protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in decreased expression of SLC40A1 protein] 		CTD PMID:32129080 PMID:37690746 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460 		JBrowse link
G Slc43a1 solute carrier family 43 member 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SLC43A1 mRNA CTD PMID:24356939 NCBI chr 3:90,327,250...90,353,438
Ensembl chr 3:90,327,149...90,353,438 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 affects expression
multiple interactions
decreases expression 		ISO Cyclophosphamide affects the expression of SLC7A11 mRNA
Dexrazoxane inhibits the reaction [Cyclophosphamide results in decreased expression of SLC7A11 protein]
Cyclophosphamide metabolite results in decreased expression of SLC7A11 mRNA 		CTD PMID:23824090 PMID:24356939 PMID:37690746 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Slfn4 schlafen family member 4 increases expression ISO Cyclophosphamide results in increased expression of SLFN4 mRNA CTD PMID:15331540 NCBI chr10:67,994,601...68,018,141 JBrowse link
G Slit1 slit guidance ligand 1 decreases expression ISO Cyclophosphamide results in decreased expression of SLIT1 mRNA CTD PMID:20849824 NCBI chr 1:250,358,917...250,507,476
Ensembl chr 1:250,358,919...250,507,476 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Cyclophosphamide results in decreased expression of SLPI mRNA CTD PMID:15331540 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822 		JBrowse link
G Snx10 sorting nexin 10 increases expression ISO Cyclophosphamide results in increased expression of SNX10 mRNA CTD PMID:15331540 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:81,943,287...82,007,651 		JBrowse link
G Soat1 sterol O-acyltransferase 1 affects response to substance ISO SOAT1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:71,105,178...71,147,776
Ensembl chr13:71,105,178...71,147,672 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Cyclophosphamide results in decreased expression of SOCS1 mRNA CTD PMID:21041162 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 increases expression EXP Cyclophosphamide results in increased expression of SOCS7 mRNA CTD PMID:11599041 NCBI chr10:82,848,525...82,885,201
Ensembl chr10:82,848,612...82,885,201 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
multiple interactions
decreases activity 		ISO
EXP 		Cyclophosphamide results in decreased expression of SOD1 mRNA
allyl sulfide inhibits the reaction [Cyclophosphamide results in decreased activity of SOD1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in decreased activity of SOD1 protein]
[Doxorubicin co-treated with Cyclophosphamide] results in increased expression of SOD1 protein; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of SOD1 mRNA] 		CTD PMID:23542512 PMID:29228376 PMID:31779506 PMID:35906875 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
affects response to substance
decreases expression 		ISO
EXP 		Cyclophosphamide results in increased expression of SOD2 mRNA
SOD2 polymorphism affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of SOD2 mRNA 		CTD PMID:11599041 PMID:11906922 PMID:15331540 PMID:20309628 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sord sorbitol dehydrogenase decreases activity
multiple interactions 		EXP Cyclophosphamide results in decreased activity of SORD protein
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of SORD protein] 		CTD PMID:25446862 NCBI chr 3:129,638,282...129,669,727
Ensembl chr 3:129,638,302...129,686,100 		JBrowse link
G Sp2 Sp2 transcription factor decreases expression EXP Cyclophosphamide results in decreased expression of SP2 mRNA CTD PMID:27281708 NCBI chr10:82,437,024...82,467,583
Ensembl chr10:82,437,029...82,467,651 		JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression
increases expression 		ISO Cyclophosphamide results in decreased expression of SPARC mRNA
Cyclophosphamide results in increased expression of SPARC mRNA 		CTD PMID:15331540 PMID:17403535 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects response to substance
increases expression
affects expression 		ISO
EXP 		SPP1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of SPP1 mRNA
Cyclophosphamide affects the expression of SPP1 mRNA 		CTD PMID:16217747 PMID:20623750 PMID:23558518 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Srek1ip1 SREK1-interacting protein 1 increases expression EXP Cyclophosphamide results in increased expression of SREK1IP1 mRNA CTD PMID:27281708 NCBI chr 2:35,975,978...35,999,636
Ensembl chr 2:37,709,768...37,733,383
Ensembl chr 7:37,709,768...37,733,383 		JBrowse link
G Srm spermidine synthase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of SRM mRNA CTD PMID:16322899 NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705 		JBrowse link
G Ssrp1 structure specific recognition protein 1 increases expression EXP Cyclophosphamide results in increased expression of SSRP1 mRNA CTD PMID:11599041 NCBI chr 3:90,531,024...90,541,132
Ensembl chr 3:90,530,829...90,541,129 		JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression EXP Cyclophosphamide results in increased expression of ST13 mRNA CTD PMID:11599041 NCBI chr 7:114,769,758...114,805,877
Ensembl chr 7:114,769,759...114,805,941 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ST14 mRNA CTD PMID:16322899 NCBI chr 8:37,798,994...37,839,881
Ensembl chr 8:37,798,995...37,855,652 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression 		EXP
ISO 		[Rutin co-treated with Chitosan] inhibits the reaction [Cyclophosphamide results in decreased expression of STAR mRNA]
Cyclophosphamide results in decreased expression of STAR mRNA; Cyclophosphamide results in decreased expression of STAR protein
Flavonoids inhibits the reaction [Cyclophosphamide results in decreased expression of STAR mRNA]; Flavonoids inhibits the reaction [Cyclophosphamide results in decreased expression of STAR protein] 		CTD PMID:38211767 PMID:39239657 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Cyclophosphamide results in increased expression of STAT1 mRNA CTD PMID:21041162 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
decreases expression
multiple interactions
decreases phosphorylation 		EXP
ISO 		Cyclophosphamide results in increased phosphorylation of STAT3 protein
Cyclophosphamide results in decreased expression of STAT3 mRNA
ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of STAT3 mRNA]
chrysin inhibits the reaction [Cyclophosphamide results in increased phosphorylation of STAT3 protein]
Cyclophosphamide results in decreased phosphorylation of STAT3 protein 		CTD PMID:19625377 PMID:21880982 PMID:37263553 PMID:37853057 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases expression ISO Cyclophosphamide results in decreased expression of STAT5B mRNA CTD PMID:21041162 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO
EXP 		Cyclophosphamide results in decreased expression of STIP1 mRNA CTD PMID:11906922 PMID:15331540 NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654 		JBrowse link
G Stk39 serine threonine kinase 39 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of STK39 mRNA CTD PMID:16322899 NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:73,321,522...73,586,740 		JBrowse link
G Stk4 serine/threonine kinase 4 decreases expression ISO Cyclophosphamide results in decreased expression of STK4 mRNA CTD PMID:21041162 NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:173,165,083...173,247,134 		JBrowse link
G Stmn3 stathmin 3 increases expression ISO Cyclophosphamide results in increased expression of STMN3 mRNA CTD PMID:21527772 NCBI chr 3:188,794,358...188,802,494
Ensembl chr 3:188,794,358...188,802,873 		JBrowse link
G Stom stomatin increases expression ISO Cyclophosphamide results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:39,042,503...39,064,818 		JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression EXP Cyclophosphamide results in decreased expression of SUN1 mRNA CTD PMID:27281708 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:20,490,861...20,555,240 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression
increases secretion
affects expression 		EXP
ISO 		Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased secretion of TAC1 protein]
Cyclophosphamide results in increased expression of TAC1 protein
Cyclophosphamide affects the expression of TAC1 mRNA 		CTD PMID:11312054 PMID:18184328 PMID:18563302 PMID:22842586 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions
increases expression
decreases response to substance 		ISO
EXP 		[alpha-amyrin co-treated with beta-amyrin] inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]
TACR1 gene mutant form results in decreased susceptibility to Cyclophosphamide 		CTD PMID:10854767 PMID:18210232 PMID:23666265 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492 		JBrowse link
G Tafa5 TAFA chemokine like family member 5 increases expression ISO Cyclophosphamide results in increased expression of TAFA5 mRNA CTD PMID:21621594 NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:120,493,060...120,714,718 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO Cyclophosphamide results in increased expression of TAP1 mRNA CTD PMID:21527772 NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810 		JBrowse link
G Tat tyrosine aminotransferase affects expression
decreases expression 		EXP Cyclophosphamide affects the expression of TAT mRNA
Cyclophosphamide results in decreased expression of TAT mRNA 		CTD PMID:18246545 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482 		JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions
decreases expression 		ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TBX21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TBX21 protein] CTD PMID:32151603 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
G Tcf7 transcription factor 7 decreases expression ISO Cyclophosphamide results in decreased expression of TCF7 mRNA CTD PMID:21041162 NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,924,363...36,954,279 		JBrowse link
G Tcp1 t-complex 1 decreases expression
increases expression 		EXP Cyclophosphamide results in decreased expression of TCP1 mRNA
Cyclophosphamide results in increased expression of TCP1 mRNA 		CTD PMID:11599041 PMID:11906922 NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase increases activity
multiple interactions 		EXP Cyclophosphamide results in increased activity of TDO2 protein
Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of TDO2 protein] 		CTD PMID:35906875 NCBI chr 2:169,567,656...169,585,586
Ensembl chr 2:169,567,654...169,585,586 		JBrowse link
G Tex30 testis expressed 30 decreases expression ISO Cyclophosphamide results in decreased expression of TEX30 mRNA CTD PMID:17403535 NCBI chr 9:53,735,512...53,744,672
Ensembl chr 9:53,735,512...53,741,042 		JBrowse link
G Tfrc transferrin receptor decreases expression ISO Cyclophosphamide results in decreased expression of TFRC protein CTD PMID:32129080 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
increases secretion
multiple interactions
affects expression 		ISO
EXP 		Cyclophosphamide results in increased expression of TGFB1 mRNA
Cyclophosphamide results in increased expression of TGFB1 mRNA; Cyclophosphamide results in increased expression of TGFB1 protein
Cyclophosphamide results in increased secretion of TGFB1 protein
Cyclophosphamide results in increased expression of and results in increased activity of TGFB1 protein; naringin inhibits the reaction [Cyclophosphamide results in increased expression of TGFB1 mRNA]
Cyclophosphamide affects the expression of TGFB1 mRNA
DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa] 		CTD PMID:9509296 PMID:12624490 PMID:19691848 PMID:21068404 PMID:23926183 More... NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Cyclophosphamide results in increased expression of TGFB2 mRNA CTD PMID:23558518 PMID:23926183 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
increases expression
decreases expression 		ISO
EXP 		Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TGFB3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TGFB3 protein]
Cyclophosphamide results in increased expression of TGFB3 mRNA; Cyclophosphamide results in increased expression of TGFB3 protein 		CTD PMID:23926183 PMID:32151603 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Cyclophosphamide results in increased expression of TGFBR1 mRNA; Cyclophosphamide results in increased expression of TGFBR1 protein CTD PMID:23926183 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO
EXP 		Cyclophosphamide results in increased expression of TGFBR2 mRNA
Cyclophosphamide results in increased expression of TGFBR2 mRNA; Cyclophosphamide results in increased expression of TGFBR2 protein 		CTD PMID:21041162 PMID:23926183 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 increases expression EXP Cyclophosphamide results in increased expression of TGFBR3 mRNA; Cyclophosphamide results in increased expression of TGFBR3 protein CTD PMID:23926183 NCBI chr14:2,634,294...2,810,269
Ensembl chr14:2,634,188...2,810,271 		JBrowse link
G Thbs1 thrombospondin 1 increases expression
multiple interactions 		EXP
ISO 		Cyclophosphamide results in increased expression of THBS1 protein
Cyclophosphamide results in increased expression of THBS1 mRNA
axitinib inhibits the reaction [Cyclophosphamide results in increased expression of THBS1 protein] 		CTD PMID:15331540 PMID:18202011 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Thnsl2 threonine synthase-like 2 multiple interactions ISO THNSL2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:104,670,925...104,691,959 		JBrowse link
G Thpo thrombopoietin decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of THPO protein
asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of THPO protein]; CSF2 protein inhibits the reaction [Cyclophosphamide results in decreased expression of THPO protein]; dorsomorphin inhibits the reaction [asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of THPO protein]] 		CTD PMID:38348709 Ensembl chr11:93,686,834...93,693,320 JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression ISO Cyclophosphamide results in decreased expression of THY1 mRNA CTD PMID:21041162 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Cyclophosphamide results in increased expression of TIMP1 mRNA CTD PMID:23558518 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression 		EXP
ISO 		Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein] 		CTD PMID:25451569 PMID:32151603 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tk1 thymidine kinase 1 increases mutagenesis ISO Cyclophosphamide metabolite results in increased mutagenesis of TK1 gene CTD PMID:32087850 NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,533,449...103,556,228 		JBrowse link
G Tlr2 toll-like receptor 2 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of TLR2 mRNA
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TLR2 mRNA] 		CTD PMID:32151603 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
decreases expression 		ISO Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]; Donepezil inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein]; fosaprepitant inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR4 mRNA]; levocabastine inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein] CTD PMID:32151603 PMID:36031164 PMID:38278497 PMID:38825044 PMID:39378958 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tlr6 toll-like receptor 6 decreases expression
multiple interactions 		ISO Cyclophosphamide results in decreased expression of TLR6 mRNA
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR6 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TLR6 mRNA] 		CTD PMID:32151603 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,698,751...43,740,462 		JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
increases expression 		ISO Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TLR9 mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of TLR9 protein] CTD PMID:29753871 PMID:36031164 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO Cyclophosphamide results in increased expression of TM4SF1 mRNA CTD PMID:17403535 NCBI chr 2:143,606,980...143,616,176
Ensembl chr 2:143,603,271...143,616,176 		JBrowse link
G Tm6sf1 transmembrane 6 superfamily member 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TM6SF1 mRNA CTD PMID:24356939 NCBI chr 1:145,209,052...145,237,725
Ensembl chr 1:145,209,585...145,237,715 		JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 decreases expression ISO Cyclophosphamide results in decreased expression of TMED3 mRNA CTD PMID:15331540 NCBI chr 8:99,121,361...99,129,653
Ensembl chr 8:99,121,361...99,129,215 		JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 affects response to substance
decreases expression 		ISO
EXP 		TMEFF1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of TMEFF1 mRNA 		CTD PMID:16217747 PMID:27466211 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:67,706,269...67,792,021 		JBrowse link
G Tmem267 transmembrane protein 267 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TMEM267 mRNA CTD PMID:24356939 NCBI chr 2:53,309,857...53,321,466
Ensembl chr 2:53,313,021...53,320,835 		JBrowse link
G Tnf tumor necrosis factor affects expression
increases secretion
multiple interactions
decreases expression
increases expression
decreases response to substance
increases response to substance 		ISO
EXP 		Cyclophosphamide affects the expression of TNF mRNA
Cyclophosphamide results in increased secretion of TNF protein
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]
Cyclophosphamide results in decreased expression of TNF mRNA; Cyclophosphamide results in decreased expression of TNF protein
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of TNF protein; [Cyclophosphamide co-treated with Methylprednisolone] inhibits the reaction [Paraquat results in increased expression of TNF protein]; Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Donepezil inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of TNF mRNA]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of TNF protein]; levocabastine inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Cyclophosphamide results in increased expression of TNF mRNA; Cyclophosphamide results in increased expression of TNF protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of TNF protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Berberine inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of TNF mRNA]; crocin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; herbacetin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Cyclophosphamide affects the expression of TNF protein
TNF protein results in decreased susceptibility to Cyclophosphamide
TNF protein results in increased susceptibility to Cyclophosphamide 		CTD PMID:8634684 PMID:11948286 PMID:12797522 PMID:18206168 PMID:18710439 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Cyclophosphamide results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO Cyclophosphamide results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 5:170,768,413...170,776,749
Ensembl chr 5:170,768,416...170,776,046 		JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 decreases expression ISO Cyclophosphamide results in decreased expression of TNFRSF18 mRNA CTD PMID:15591121 NCBI chr 5:171,901,734...171,904,578
Ensembl chr 5:171,901,717...171,904,576 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of TNFRSF19 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of TNFRSF19 mRNA] 		CTD PMID:30760223 NCBI chr15:39,268,305...39,334,566
Ensembl chr15:39,268,305...39,356,438 		JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Cyclophosphamide results in increased expression of TNFSF9 mRNA CTD PMID:21527772 NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression
multiple interactions 		ISO
EXP 		Cyclophosphamide results in increased expression of TNNI3 protein
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein]; levocabastine inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein]
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein] 		CTD PMID:17562616 PMID:18548196 PMID:35762198 PMID:38278497 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
increases expression 		ISO
EXP 		TOP2A protein affects the susceptibility to [Cyclophosphamide co-treated with Epirubicin co-treated with Fluorouracil]; TOP2A protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
Cyclophosphamide results in increased expression of TOP2A mRNA 		CTD PMID:11599041 PMID:16682728 PMID:18465341 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases activity
increases expression
increases mutagenesis
affects response to substance 		EXP
ISO 		astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein]; chlorophyllin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]; Curcumin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of TP53 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of TP53 mRNA]
Cyclophosphamide results in increased expression of and results in increased phosphorylation of TRP53 protein; TRPM2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of TRP53 protein]
Cyclophosphamide metabolite results in increased activity of TP53 protein
TP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Cyclophosphamide metabolite]
Cyclophosphamide results in increased expression of TP53 mRNA; Cyclophosphamide results in increased expression of TP53 protein
TRP53 affects the susceptibility to Cyclophosphamide
TP53 protein affects the susceptibility to Cyclophosphamide 		CTD PMID:9610789 PMID:10766175 PMID:15182437 PMID:19227835 PMID:20038455 More... NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpd52 tumor protein D52 decreases expression ISO Cyclophosphamide results in decreased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241 		JBrowse link
G Tpm1 tropomyosin 1 affects response to substance
increases expression 		ISO
EXP 		TPM1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of TPM1 protein 		CTD PMID:15928459 PMID:16217747 NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression EXP Cyclophosphamide results in increased expression of TRAF2 protein CTD PMID:38740238 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TRIB3 mRNA CTD PMID:24356939 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802 		JBrowse link
G Trim32 tripartite motif-containing 32 increases expression EXP Cyclophosphamide results in increased expression of TRIM32 mRNA CTD PMID:27281708 NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:84,014,803...84,042,748 		JBrowse link
G Trim58 tripartite motif-containing 58 increases expression EXP Cyclophosphamide results in increased expression of TRIM58 mRNA CTD PMID:27281708 NCBI chr10:43,022,933...43,038,984
Ensembl chr10:43,523,372...43,535,784 		JBrowse link
G Triml1 tripartite motif family-like 1 decreases expression EXP Cyclophosphamide results in decreased expression of TRIML1 mRNA CTD PMID:27281708 NCBI chr16:48,994,968...49,005,343
Ensembl chr16:55,729,691...55,737,769 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions EXP [2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide binds to and results in decreased activity of TRPA1 protein] which results in decreased susceptibility to Cyclophosphamide CTD PMID:23523557 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of TRPM2 mRNA
TRPM2 protein affects the reaction [Cyclophosphamide results in decreased expression of GCLM mRNA]; TRPM2 protein affects the reaction [Cyclophosphamide results in decreased expression of HMOX1 mRNA]; TRPM2 protein affects the reaction [Cyclophosphamide results in decreased expression of NQO1 mRNA]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of CASP3 mRNA]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of H2AX protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of S100A1 protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased expression of S100B protein]; TRPM2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of TRP53 protein] 		CTD PMID:39952379 NCBI chr20:10,703,190...10,752,795
Ensembl chr20:10,704,482...10,752,802 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 decreases expression EXP Cyclophosphamide results in decreased expression of TRPV1 mRNA alternative form CTD PMID:18797299 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO Cyclophosphamide results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 9:84,158,871...84,174,041
Ensembl chr 9:84,158,280...84,162,584 		JBrowse link
G Tubb2b tubulin, beta 2B class IIb decreases expression ISO Cyclophosphamide results in decreased expression of TUBB2B mRNA CTD PMID:21041162 NCBI chr17:30,953,086...30,956,133
Ensembl chr17:30,952,923...30,955,990 		JBrowse link
G Tug1 taurine up-regulated 1 decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of TUG1 mRNA
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of TUG1 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of TUG1 mRNA] 		CTD PMID:32197949 NCBI chr14:82,743,501...82,750,534
Ensembl chr14:82,746,113...82,750,534 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions
decreases expression 		ISO ganoderic acid A inhibits the reaction [Cyclophosphamide results in decreased expression of TXN protein] CTD PMID:30506662 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of TXNIP protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of TXNIP protein] 		CTD PMID:30506662 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity ISO Cyclophosphamide results in decreased activity of TXNRD1 protein CTD PMID:19168513 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of TYMP protein; [Epirubicin co-treated with Cyclophosphamide] results in increased expression of TYMP protein CTD PMID:15150550 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp increases expression ISO Cyclophosphamide results in increased expression of TYROBP mRNA CTD PMID:21041162 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
G Ubd ubiquitin D increases expression ISO Cyclophosphamide results in increased expression of UBD mRNA CTD PMID:15331540 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,390,600...1,413,965 		JBrowse link
G Ubr7 ubiquitin protein ligase E3 component n-recognin 7 increases expression EXP Cyclophosphamide results in increased expression of UBR7 mRNA CTD PMID:27281708 NCBI chr 6:121,898,613...121,918,480
Ensembl chr 6:127,663,447...127,694,390 		JBrowse link
G Ucp1 uncoupling protein 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of UCP1 mRNA CTD PMID:24356939 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420 		JBrowse link
G Umod uromodulin decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of UMOD protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in decreased expression of UMOD protein] 		CTD PMID:32615180 NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:183,247,674...183,261,030 		JBrowse link
G Ung uracil-DNA glycosylase decreases expression EXP Cyclophosphamide results in decreased expression of UNG mRNA CTD PMID:11056294 NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257 		JBrowse link
G Upk1a uroplakin 1A decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of UPK1A mRNA
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK1A mRNA] 		CTD PMID:19654953 PMID:20186394 NCBI chr 1:94,987,110...94,998,083
Ensembl chr 1:94,987,108...94,997,787 		JBrowse link
G Upk1b uroplakin 1B decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of UPK1B mRNA
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK1B mRNA] 		CTD PMID:19654953 PMID:20186394 NCBI chr11:61,953,687...61,991,029
Ensembl chr11:75,459,200...75,496,579 		JBrowse link
G Upk2 uroplakin 2 decreases expression
increases export
multiple interactions 		EXP
ISO 		Cyclophosphamide results in decreased expression of UPK2 mRNA; Cyclophosphamide results in decreased expression of UPK2 protein
Cyclophosphamide results in increased export of UPK2 protein
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 mRNA]; Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 protein]; S-allylcysteine inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 mRNA]; S-allylcysteine inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 protein] 		CTD PMID:19654953 PMID:20186394 PMID:26424769 PMID:27234646 NCBI chr 8:53,675,994...53,677,986
Ensembl chr 8:53,675,994...53,677,986 		JBrowse link
G Upk3a uroplakin 3A decreases expression
multiple interactions 		EXP Cyclophosphamide results in decreased expression of UPK3A mRNA; Cyclophosphamide results in decreased expression of UPK3A protein
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK3A mRNA]; Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK3A protein] 		CTD PMID:19654953 PMID:20186394 NCBI chr 7:116,128,981...116,139,950
Ensembl chr 7:118,014,108...118,019,870 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Cyclophosphamide results in increased expression of USP36 mRNA CTD PMID:20849824 NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,995,970...104,023,450 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 decreases expression EXP Cyclophosphamide results in decreased expression of USP44 mRNA CTD PMID:27281708 NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:30,251,205...30,297,906 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 increases expression
multiple interactions 		ISO Cyclophosphamide results in increased expression of USP5 protein
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein 		CTD PMID:29129814 NCBI chr 4:159,305,927...159,321,345
Ensembl chr 4:159,305,938...159,320,956 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO Cyclophosphamide results in increased expression of VCAM1 mRNA CTD PMID:15331540 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vcp valosin-containing protein increases expression EXP Cyclophosphamide results in increased expression of VCP protein CTD PMID:15928459 NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387 		JBrowse link
G Vdr vitamin D receptor increases expression EXP Cyclophosphamide results in increased expression of VDR mRNA CTD PMID:27281708 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
affects expression
increases expression 		ISO
EXP 		Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]
Cyclophosphamide metabolite results in decreased expression of VEGFA mRNA
Cyclophosphamide affects the expression of VEGFA protein
Cyclophosphamide results in increased expression of VEGFA mRNA 		CTD PMID:18632792 PMID:24356939 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin affects expression EXP Cyclophosphamide affects the expression of VIM mRNA CTD PMID:10859244 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vip vasoactive intestinal peptide multiple interactions
affects response to substance
affects expression 		ISO
EXP 		VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of CXCL1 protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
VIP affects the susceptibility to Cyclophosphamide
Cyclophosphamide affects the expression of VIP mRNA 		CTD PMID:18299998 PMID:18483878 PMID:18563302 NCBI chr 1:44,470,232...44,478,561
Ensembl chr 1:44,470,462...44,478,558 		JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 increases expression EXP Cyclophosphamide results in increased expression of VIPR1 mRNA CTD PMID:18563302 NCBI chr 8:130,181,219...130,217,098
Ensembl chr 8:130,187,731...130,217,096 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 affects expression EXP Cyclophosphamide affects the expression of VIPR2 mRNA CTD PMID:18563302 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:143,144,523...143,213,609 		JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO Cyclophosphamide metabolite results in decreased expression of VLDLR mRNA CTD PMID:24356939 NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:234,240,121...234,272,154 		JBrowse link
G Was WASP actin nucleation promoting factor decreases expression ISO Cyclophosphamide results in decreased expression of WAS mRNA CTD PMID:21041162 NCBI chr  X:17,077,057...17,085,802
Ensembl chr  X:17,073,314...17,085,802 		JBrowse link
G Wnt3a Wnt family member 3A multiple interactions
decreases expression 		EXP coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of WNT3A protein] CTD PMID:39209270 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919 		JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of XAF1 mRNA CTD PMID:24356939 NCBI chr10:57,415,935...57,428,348
Ensembl chr10:57,415,658...57,428,349 		JBrowse link
G Xbp1 X-box binding protein 1 increases expression EXP Cyclophosphamide results in increased expression of XBP1 protein alternative form CTD PMID:38740238 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions 		EXP Cyclophosphamide results in increased activity of XDH protein
Rutin inhibits the reaction [Cyclophosphamide results in increased activity of XDH protein] 		CTD PMID:25753322 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
G Xist X inactive specific transcript increases expression ISO Cyclophosphamide results in increased expression of XIST mRNA CTD PMID:15331540 NCBI chr  X:72,540,753...72,558,266 JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor affects expression
increases expression 		EXP
ISO 		Cyclophosphamide affects the expression of XPC mRNA
Cyclophosphamide results in increased expression of XPC mRNA 		CTD PMID:11056294 PMID:29445054 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression EXP Cyclophosphamide results in decreased expression of XRCC1 mRNA CTD PMID:11056294 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 decreases expression ISO Cyclophosphamide results in decreased expression of XRCC6 mRNA CTD PMID:21041162 NCBI chr 7:115,423,026...115,443,884
Ensembl chr 7:115,422,662...115,443,884 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions EXP Cyclophosphamide results in decreased expression of and results in increased phosphorylation of YAP1 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of and results in increased phosphorylation of YAP1 protein] CTD PMID:36154502 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437 		JBrowse link
G Ybx3 Y box binding protein 3 decreases expression EXP Cyclophosphamide results in decreased expression of YBX3 protein CTD PMID:15928459 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 decreases expression ISO Cyclophosphamide results in decreased expression of ZAP70 mRNA CTD PMID:21041162 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:46,485,598...46,509,062 		JBrowse link
G Zbtb33 zinc finger and BTB domain containing 33 increases expression EXP Cyclophosphamide results in increased expression of ZBTB33 mRNA CTD PMID:27281708 NCBI chr  X:116,963,337...116,970,547
Ensembl chr  X:121,828,952...121,839,399 		JBrowse link
G Zbtb41 zinc finger and BTB domain containing 41 increases expression EXP Cyclophosphamide results in increased expression of ZBTB41 mRNA CTD PMID:27281708 NCBI chr13:53,591,961...53,622,007
Ensembl chr13:53,592,797...53,617,780 		JBrowse link
G Zc3h12b zinc finger CCCH-type containing 12B decreases expression EXP Cyclophosphamide results in decreased expression of ZC3H12B mRNA CTD PMID:27281708 NCBI chr  X:60,615,616...60,849,278
Ensembl chr  X:64,625,161...64,858,633 		JBrowse link
G Zc3h15l1 zinc finger CCCH-type containing 15 like 1 increases expression EXP Cyclophosphamide results in increased expression of ZC3H15L1 mRNA CTD PMID:27281708 NCBI chr17:43,670,444...43,671,788
Ensembl chr17:48,366,221...48,367,501 		JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 decreases expression EXP Cyclophosphamide results in decreased expression of ZDHHC1 mRNA CTD PMID:27281708 NCBI chr19:50,260,445...50,285,634
Ensembl chr19:50,260,445...50,271,957 		JBrowse link
G Zfp142 zinc finger protein 142 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP142 mRNA CTD PMID:27281708 NCBI chr 9:76,141,053...76,164,784
Ensembl chr 9:83,591,318...83,613,896 		JBrowse link
G Zfp169 zinc finger protein 169 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP169 mRNA CTD PMID:27281708 NCBI chr17:16,139,204...16,167,242
Ensembl chr17:16,345,647...16,373,928 		JBrowse link
G Zfp219 zinc finger protein 219 increases expression EXP Cyclophosphamide results in increased expression of ZFP219 mRNA CTD PMID:27281708 NCBI chr15:24,695,831...24,710,039
Ensembl chr15:27,169,339...27,182,926 		JBrowse link
G Zfp24 zinc finger protein 24 increases expression EXP Cyclophosphamide results in increased expression of ZFP24 mRNA CTD PMID:27281708 NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,574,762...15,582,290 		JBrowse link
G Zfp263 zinc finger protein 263 increases expression EXP Cyclophosphamide results in increased expression of ZFP263 mRNA CTD PMID:27281708 NCBI chr10:12,270,785...12,280,982
Ensembl chr10:12,234,057...12,277,587 		JBrowse link
G Zfp280d zinc finger protein 280D increases expression EXP Cyclophosphamide results in increased expression of ZFP280D mRNA CTD PMID:27281708 NCBI chr 8:81,872,108...81,961,194
Ensembl chr 8:81,873,335...81,961,201 		JBrowse link
G Zfp318 zinc finger protein 318 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP318 mRNA CTD PMID:27281708 NCBI chr 9:14,562,958...14,601,557
Ensembl chr 9:22,060,916...22,099,551 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP36L1 mRNA CTD PMID:27281708 NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979 		JBrowse link
G Zfp385a zinc finger protein 385A decreases expression EXP Cyclophosphamide results in decreased expression of ZFP385A mRNA CTD PMID:27281708 NCBI chr 7:136,327,393...136,354,017
Ensembl chr 7:136,327,393...136,354,321 		JBrowse link
G Zfp385c zinc finger protein 385C increases expression EXP Cyclophosphamide results in increased expression of ZFP385C mRNA CTD PMID:27281708 NCBI chr10:85,562,003...85,618,100
Ensembl chr10:86,062,512...86,106,063 		JBrowse link
G Zfp385d zinc finger protein 385D decreases expression EXP Cyclophosphamide results in decreased expression of ZFP385D mRNA CTD PMID:27281708 NCBI chr15:5,040,182...5,849,975
Ensembl chr15:7,473,435...8,504,582 		JBrowse link
G Zfp40 zinc finger protein 40 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP40 mRNA CTD PMID:27281708 NCBI chr 1:62,962,456...62,985,007
Ensembl chr 1:71,636,452...71,658,827 		JBrowse link
G Zfp414 zinc finger protein 414 increases expression EXP Cyclophosphamide results in increased expression of ZFP414 mRNA CTD PMID:27281708 NCBI chr 7:14,420,232...14,422,939
Ensembl chr 7:15,122,401...15,125,755 		JBrowse link
G Zfp513 zinc finger protein 513 increases expression EXP Cyclophosphamide results in increased expression of ZFP513 mRNA CTD PMID:27281708 NCBI chr 6:30,894,153...30,897,414
Ensembl chr 6:30,894,079...30,897,413 		JBrowse link
G Zfp532 zinc finger protein 532 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP532 mRNA CTD PMID:27281708 NCBI chr18:59,080,082...59,203,672
Ensembl chr18:61,364,378...61,473,649 		JBrowse link
G Zfp622 zinc finger protein 622 increases expression EXP Cyclophosphamide results in increased expression of ZFP622 mRNA CTD PMID:27281708 NCBI chr 2:78,205,655...78,224,888
Ensembl chr 2:78,066,031...78,225,356 		JBrowse link
G Zfp652 zinc finger protein 652 increases expression EXP Cyclophosphamide results in increased expression of ZFP652 mRNA CTD PMID:27281708 NCBI chr10:81,123,326...81,203,153
Ensembl chr10:81,146,507...81,198,827 		JBrowse link
G Zfp655 zinc finger protein 655 decreases expression EXP Cyclophosphamide results in decreased expression of ZFP655 mRNA CTD PMID:27281708 NCBI chr12:9,349,985...9,375,449
Ensembl chr12:14,471,415...14,488,678 		JBrowse link
G Zfp827 zinc finger protein 827 increases expression EXP Cyclophosphamide results in increased expression of ZFP827 mRNA CTD PMID:27281708 NCBI chr19:45,624,849...45,791,739
Ensembl chr19:45,614,604...45,844,430 		JBrowse link
G Zfr zinc finger RNA binding protein decreases expression EXP Cyclophosphamide results in decreased expression of ZFR mRNA CTD PMID:27281708 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:62,864,338...62,929,133 		JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 decreases expression EXP Cyclophosphamide results in decreased expression of ZHX3 mRNA CTD PMID:27281708 NCBI chr 3:169,837,497...169,968,371
Ensembl chr 3:169,837,516...169,935,530 		JBrowse link
G Zic1 Zic family member 1 affects response to substance ISO ZIC1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 8:91,908,548...91,918,020
Ensembl chr 8:100,787,789...100,792,427 		JBrowse link
G Zzef1 zinc finger ZZ-type and EF-hand domain containing 1 increases expression EXP Cyclophosphamide results in increased expression of ZZEF1 mRNA CTD PMID:27281708 NCBI chr10:57,911,728...58,049,412
Ensembl chr10:57,911,728...58,049,412 		JBrowse link
ifosfamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions 		ISO Ifosfamide results in increased expression of ABCB1 protein
[Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein] 		CTD PMID:20041327 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Ifosfamide results in increased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526 		JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Ifosfamide results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:38,146,659...38,192,862
Ensembl chr12:38,159,904...38,192,860 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Ifosfamide results in decreased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563 		JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Ifosfamide results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:31,674,143...31,687,007 		JBrowse link
G Ache acetylcholinesterase increases activity
multiple interactions 		EXP Ifosfamide results in increased activity of ACHE protein
morin inhibits the reaction [Ifosfamide results in increased activity of ACHE protein] 		CTD PMID:31722249 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Ifosfamide results in decreased expression of ACSL1 mRNA CTD PMID:25596134 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023 		JBrowse link
G Agrn agrin increases expression ISO Ifosfamide results in increased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539 		JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO Ifosfamide affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO Ifosfamide results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Ifosfamide results in increased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Ifosfamide results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Ifosfamide results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211 		JBrowse link
G Als2cl ALS2 C-terminal like affects expression ISO Ifosfamide affects the expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:119,743,248...119,762,843 		JBrowse link
G Ankra2 ankyrin repeat family A member 2 decreases expression ISO Ifosfamide results in decreased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:31,347,090...31,364,394 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 affects expression ISO Ifosfamide affects the expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:81,349,429...81,440,054 		JBrowse link
G Arln allregulin decreases expression ISO Ifosfamide results in decreased expression of ARLN mRNA CTD PMID:25596134 NCBI chr 2:211,055,925...211,057,685
Ensembl chr 2:213,740,525...213,742,952 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ifosfamide results in increased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Atf4 activating transcription factor 4 affects activity ISO Ifosfamide affects the activity of ATF4 protein CTD PMID:25596134 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atosa atos homolog A decreases expression ISO Ifosfamide results in decreased expression of ATOSA mRNA CTD PMID:25596134 NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091 		JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Ifosfamide results in decreased expression of ATXN1 mRNA CTD PMID:25596134 NCBI chr17:18,943,397...19,354,751
Ensembl chr17:19,208,200...19,356,790 		JBrowse link
G Aurkb aurora kinase B increases expression ISO Ifosfamide results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Ifosfamide co-treated with Mesna] results in increased expression of AVP protein CTD PMID:2261371 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Ifosfamide results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009 		JBrowse link
G B2m beta-2 microglobulin increases expression ISO Ifosfamide results in increased expression of B2M protein CTD PMID:8625085 PMID:9261752 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Ifosfamide results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression ISO Ifosfamide results in decreased expression of BCAT1 mRNA CTD PMID:25596134 NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288 		JBrowse link
G Bche butyrylcholinesterase increases activity
multiple interactions 		EXP Ifosfamide results in increased activity of BCHE protein
morin inhibits the reaction [Ifosfamide results in increased activity of BCHE protein] 		CTD PMID:31722249 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression 		ISO
EXP 		BCL2 protein inhibits the reaction [Ifosfamide results in increased activity of CASP9 protein]
Carnitine inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; morin inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA] 		CTD PMID:11723234 PMID:23213347 PMID:31722249 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression 		EXP morin inhibits the reaction [Ifosfamide results in increased expression of BDNF mRNA] CTD PMID:31722249 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Ifosfamide results in decreased expression of BGLAP protein CTD PMID:1525342 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Ifosfamide results in increased expression of BHLHE40 mRNA CTD PMID:25596134 NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Ifosfamide results in decreased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Brd2 bromodomain containing 2 decreases expression ISO Ifosfamide results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Ifosfamide results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690 		JBrowse link
G C15h8orf58 similar to human chromosome 8 open reading frame 58 increases expression ISO Ifosfamide results in increased expression of C8ORF58 mRNA CTD PMID:25596134 NCBI chr15:45,228,615...45,235,274
Ensembl chr15:51,638,350...51,642,974 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Ifosfamide results in increased expression of CAMKK2 mRNA CTD PMID:25596134 NCBI chr12:39,451,828...39,505,719
Ensembl chr12:39,451,834...39,514,964 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression ISO Ifosfamide results in decreased expression of CARS1 mRNA CTD PMID:25596134 NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407 		JBrowse link
G Casp1 caspase 1 increases response to substance ISO CASP1 results in increased susceptibility to Ifosfamide CTD PMID:9491796 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression 		EXP Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Ifosfamide results in increased activity of CASP3 protein] CTD PMID:23213347 PMID:31722249 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression 		ISO
EXP 		BCL2 protein inhibits the reaction [Ifosfamide results in increased activity of CASP9 protein]
Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP9 mRNA] 		CTD PMID:11723234 PMID:23213347 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression 		EXP Carnitine inhibits the reaction [Ifosfamide results in decreased expression of CAT mRNA]; morin inhibits the reaction [Ifosfamide results in decreased activity of CAT protein] CTD PMID:23213347 PMID:31722249 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO Ifosfamide results in decreased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:156,045,138...156,061,403 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO Ifosfamide results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Ifosfamide results in decreased expression of CCNG2 mRNA CTD PMID:25596134 NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206 		JBrowse link
G Cda cytidine deaminase multiple interactions EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Ifosfamide CTD PMID:10811482 NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 affects expression ISO Ifosfamide affects the expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Ifosfamide results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO Ifosfamide results in increased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr 7:132,738,834...132,776,920
Ensembl chr 7:132,738,834...132,776,786 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO Ifosfamide results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:84,242,512...84,301,880 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 decreases expression ISO Ifosfamide results in decreased expression of CTDP1 mRNA CTD PMID:25596134 NCBI chr18:76,129,243...76,193,404
Ensembl chr18:76,129,243...76,190,578 		JBrowse link
G Cth cystathionine gamma-lyase affects expression ISO Ifosfamide affects the expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066 		JBrowse link
G Ctsc cathepsin C increases expression ISO Ifosfamide results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082 		JBrowse link
G Cttn cortactin increases expression ISO Ifosfamide results in increased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases response to substance
decreases expression 		ISO CYP1A1 protein results in increased susceptibility to Ifosfamide
Ifosfamide results in decreased expression of CYP1A1 mRNA 		CTD PMID:20507880 PMID:25596134 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Ifosfamide results in increased expression of CYP1A2 mRNA CTD PMID:25596134 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO Ifosfamide results in decreased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases response to substance
increases activity
increases metabolic processing
increases hydroxylation 		EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Ifosfamide; Metyrapone inhibits the reaction [CYP2B1 results in increased susceptibility to Ifosfamide]; Mitomycin affects the reaction [CYP2B1 results in increased susceptibility to Ifosfamide]
CYP2B1 results in increased activity of Ifosfamide
CYP2B1 protein results in increased metabolism of Ifosfamide; CYP2B1 results in increased metabolism of Ifosfamide
CYP2B1 protein mutant form results in increased hydroxylation of Ifosfamide 		CTD PMID:2272335 PMID:7834628 PMID:8640822 PMID:9592392 PMID:10415877 More... NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases response to substance
affects metabolic processing
multiple interactions 		ISO CYP2B6 results in increased susceptibility to Ifosfamide
CYP2B6 protein affects the metabolism of Ifosfamide
POR promotes the reaction [CYP2B6 results in increased susceptibility to Ifosfamide] 		CTD PMID:9766669 PMID:15875221 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases activity
increases metabolic processing
multiple interactions
increases response to substance 		ISO CYP2C18 results in increased activity of Ifosfamide
CYP2C18 results in increased metabolism of Ifosfamide
POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide] 		CTD PMID:9241661 PMID:9766669 PMID:15301741 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases response to substance
increases activity 		ISO CYP2C19 protein results in increased susceptibility to Ifosfamide
CYP2C19 results in increased activity of Ifosfamide 		CTD PMID:9241661 PMID:20507880 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases activity ISO CYP2C8 results in increased activity of Ifosfamide CTD PMID:9241661
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases response to substance ISO CYP2D6 protein results in increased susceptibility to Ifosfamide CTD PMID:20507880 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
affects hydroxylation
affects metabolic processing
increases response to substance
affects degradation
decreases ethylation 		ISO Ifosfamide results in increased expression of CYP3A4 mRNA
CYP3A4 protein affects the hydroxylation of Ifosfamide
CYP3A4 protein affects the metabolism of Ifosfamide
CYP3A4 protein results in increased susceptibility to Ifosfamide; CYP3A4 results in increased susceptibility to Ifosfamide
CYP3A4 protein affects the degradation of Ifosfamide
CYP3A4 gene mutant form results in decreased ethylation of Ifosfamide; CYP3A4 protein results in decreased ethylation of Ifosfamide 		CTD PMID:9766669 PMID:12136253 PMID:15821045 PMID:15875221 PMID:18839173 More... NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases hydroxylation EXP CYP3A23-3A1 protein results in increased hydroxylation of Ifosfamide CTD PMID:15919850 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
decreases ethylation 		ISO CYP3A5 protein affects the metabolism of Ifosfamide
CYP3A5 protein results in decreased ethylation of Ifosfamide 		CTD PMID:15821045 PMID:15875221 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Ifosfamide results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Ifosfamide results in increased expression of DDIT4 mRNA CTD PMID:25596134 NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037 		JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO Ifosfamide results in decreased expression of DDX17 mRNA CTD PMID:25596134 NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747 		JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO Ifosfamide results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,733,248...1,759,569 		JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO Ifosfamide results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:76,763,864...76,768,454
Ensembl chr 3:76,763,500...76,768,447 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 decreases expression ISO Ifosfamide results in decreased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:237,604,068...237,666,465 		JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 increases expression ISO Ifosfamide results in increased expression of DNAJB2 mRNA CTD PMID:25596134 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:84,179,695...84,187,942 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Ifosfamide results in increased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344 		JBrowse link
G Dnmbp dynamin binding protein increases expression ISO Ifosfamide results in increased expression of DNMBP mRNA CTD PMID:25596134 NCBI chr 1:252,685,406...252,778,642
Ensembl chr 1:252,685,406...252,778,688 		JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression ISO Ifosfamide results in increased expression of DPM3 mRNA CTD PMID:25596134 NCBI chr 2:174,676,532...174,677,047
Ensembl chr15:52,612,418...52,612,696 		JBrowse link
G Dusp22 dual specificity phosphatase 22 increases expression ISO Ifosfamide results in increased expression of DUSP22 mRNA CTD PMID:25596134 NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895 		JBrowse link
G Efna1 ephrin A1 decreases expression ISO Ifosfamide results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Ifosfamide results in increased expression of EIF1 mRNA CTD PMID:25596134 NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654
Ensembl chr10:25,895,968...25,896,654 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Ifosfamide results in decreased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:190,565,184...190,583,067 		JBrowse link
G Elf4 E74 like ETS transcription factor 4 increases expression ISO Ifosfamide results in increased expression of ELF4 mRNA CTD PMID:25596134 NCBI chr  X:127,587,401...127,639,063
Ensembl chr  X:132,468,539...132,478,689 		JBrowse link
G Elk4 ETS transcription factor ELK4 decreases expression ISO Ifosfamide results in decreased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199 		JBrowse link
G Eno2 enolase 2 increases expression ISO Ifosfamide results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220 		JBrowse link
G Enosf1 enolase superfamily member 1 decreases expression ISO Ifosfamide results in decreased expression of ENOSF1 mRNA CTD PMID:25596134 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Ep400 E1A binding protein p400 decreases expression ISO Ifosfamide results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:51,551,695...51,658,634 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Ifosfamide results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039 		JBrowse link
G Exoc7 exocyst complex component 7 increases expression ISO Ifosfamide results in increased expression of EXOC7 mRNA CTD PMID:25596134 NCBI chr10:102,019,805...102,039,333
Ensembl chr10:102,019,806...102,039,447 		JBrowse link
G Fabp3 fatty acid binding protein 3 decreases expression ISO Ifosfamide results in decreased expression of FABP3 mRNA CTD PMID:25596134 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881 		JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Ifosfamide results in decreased expression of FAM162A mRNA CTD PMID:25596134 NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560 		JBrowse link
G Fam210b family with sequence similarity 210, member B decreases expression ISO Ifosfamide results in decreased expression of FAM210B mRNA CTD PMID:25596134 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:181,536,673...181,546,834 		JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Ifosfamide results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr19:69,607,391...69,620,019
Ensembl chr19:69,607,391...69,620,019 		JBrowse link
G Faslg Fas ligand increases expression ISO Ifosfamide results in increased expression of FASL CTD PMID:16453328 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO Ifosfamide results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:64,476,034...64,492,063
Ensembl chr 8:64,475,957...64,492,062 		JBrowse link
G Fbxo30 F-box protein 30 decreases expression ISO Ifosfamide results in decreased expression of FBXO30 mRNA CTD PMID:25596134 NCBI chr 1:7,475,636...7,491,719
Ensembl chr 1:7,475,575...7,493,199 		JBrowse link
G Fech ferrochelatase decreases expression ISO Ifosfamide results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546 		JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 decreases expression ISO Ifosfamide results in decreased expression of FLVCR2 mRNA CTD PMID:25596134 NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:111,139,295...111,203,345 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		EXP morin inhibits the reaction [Ifosfamide results in increased expression of FOS protein] CTD PMID:31722249 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Ifosfamide results in increased expression of FOSL1 mRNA CTD PMID:25596134 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Ifosfamide results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Ifosfamide results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Ifosfamide results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions 		EXP Ifosfamide results in increased expression of GFAP protein
morin inhibits the reaction [Ifosfamide results in increased expression of GFAP protein] 		CTD PMID:31722249 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Ifosfamide results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr14:8,715,367...8,768,051 JBrowse link
G Gpr87 G protein-coupled receptor 87 decreases expression ISO Ifosfamide results in decreased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:145,589,630...145,608,094
Ensembl chr 2:145,589,569...145,604,442 		JBrowse link
G Gpr88 G-protein coupled receptor 88 increases expression ISO Ifosfamide results in increased expression of GPR88 mRNA CTD PMID:25596134 NCBI chr 2:206,876,373...206,885,034
Ensembl chr 2:206,868,585...206,884,945 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression 		EXP Carnitine inhibits the reaction [Ifosfamide results in decreased expression of GPX1 mRNA] CTD PMID:23213347 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx3 glutathione peroxidase 3 decreases activity ISO Ifosfamide results in decreased activity of GPX3 protein CTD PMID:9851889 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Ifosfamide results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance
increases response to substance 		ISO GSTP1 gene polymorphism affects the susceptibility to Ifosfamide
GSTP1 gene polymorphism results in increased susceptibility to Ifosfamide 		CTD PMID:12868187 PMID:16282887 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 decreases expression ISO Ifosfamide results in decreased expression of HERC3 mRNA CTD PMID:25596134 NCBI chr 4:89,282,374...89,372,656
Ensembl chr 4:89,282,445...89,372,652 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects activity ISO Ifosfamide affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Ifosfamide results in increased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of IARS1 mRNA CTD PMID:25596134 NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652 		JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Ifosfamide results in decreased expression of IDS mRNA CTD PMID:25596134 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:154,070,781...154,091,444 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 mRNA; [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 protein; [Ifosfamide co-treated with IFNB1] results in decreased expression of PLAUR protein; IFNB1 promotes the reaction [Ifosfamide results in decreased activity of MMP9 protein]; IFNB1 promotes the reaction [Ifosfamide results in decreased expression of VEGFA protein] CTD PMID:15659795 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression ISO Ifosfamide results in increased expression of IGF2R mRNA CTD PMID:25596134 NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:50,526,878...50,615,265 		JBrowse link
G Il19 interleukin 19 increases secretion ISO Ifosfamide results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714 		JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions 		EXP Ifosfamide results in increased secretion of IL1B protein
resveratrol inhibits the reaction [Ifosfamide results in increased secretion of IL1B protein] 		CTD PMID:17481685 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions 		EXP Ifosfamide results in increased secretion of IL6 protein
resveratrol inhibits the reaction [Ifosfamide results in increased secretion of IL6 protein] 		CTD PMID:17481685 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Ifosfamide results in increased expression of INKA2 mRNA CTD PMID:25596134 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:195,873,497...195,893,605 		JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO Ifosfamide results in increased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 decreases expression ISO Ifosfamide results in decreased expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr 4:163,371,125...163,384,676
Ensembl chr 4:163,338,702...163,384,367 		JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO Ifosfamide affects the expression of ITGB1 mRNA CTD PMID:25596134 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO Ifosfamide results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,688,535...2,861,443
Ensembl chr15:2,688,811...2,844,343 		JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO Ifosfamide results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Ifosfamide results in increased expression of KEAP1 mRNA CTD PMID:25596134 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Krt15 keratin 15 increases expression ISO Ifosfamide results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142 		JBrowse link
G Krt19 keratin 19 increases expression ISO Ifosfamide results in increased expression of KRT19 mRNA CTD PMID:25596134 NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Ifosfamide results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 decreases expression ISO Ifosfamide results in decreased expression of LMCD1 mRNA CTD PMID:25596134 NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO Ifosfamide results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:40,090,169...40,147,303 		JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Ifosfamide results in increased expression of MAFG mRNA CTD PMID:25596134 NCBI chr10:106,401,633...106,410,159 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
multiple interactions 		EXP Ifosfamide results in increased activity of MAPK8 protein
morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] 		CTD PMID:31722249 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Ifosfamide results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Ifosfamide results in decreased expression of ME1 mRNA CTD PMID:25596134 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases activity
affects expression 		ISO [Ifosfamide co-treated with IFNA2] affects the expression of MMP9 mRNA; [Ifosfamide co-treated with IFNA2] affects the expression of MMP9 protein; [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 mRNA; [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 protein; IFNA2 promotes the reaction [Ifosfamide results in decreased activity of MMP9 protein]; IFNB1 promotes the reaction [Ifosfamide results in decreased activity of MMP9 protein]
Ifosfamide affects the expression of MMP9 mRNA 		CTD PMID:15659795 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Ifosfamide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502 		JBrowse link
G Mt2 metallothionein 2 increases expression ISO Ifosfamide results in increased expression of MT2A mRNA CTD PMID:25596134 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709 		JBrowse link
G Mtdh metadherin decreases expression ISO Ifosfamide results in decreased expression of MTDH mRNA CTD PMID:25596134 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:67,192,393...67,249,584 		JBrowse link
G Mtfp1 mitochondrial fission process 1 increases expression ISO Ifosfamide results in increased expression of MTFP1 mRNA CTD PMID:25596134 NCBI chr14:83,192,013...83,195,853
Ensembl chr14:83,192,021...83,195,927 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Ifosfamide results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:262,328,875...262,389,036 		JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 increases expression ISO Ifosfamide results in increased expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:159,655,051...159,677,938
Ensembl chr 4:159,655,051...159,677,938 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO Ifosfamide results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,495,492...23,675,668 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects activity
decreases expression
multiple interactions 		ISO
EXP 		Ifosfamide affects the activity of NFE2L2 protein
Ifosfamide results in decreased expression of NFE2L2 protein
morin inhibits the reaction [Ifosfamide results in decreased expression of NFE2L2 protein] 		CTD PMID:25596134 PMID:31722249 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nin ninein decreases expression ISO Ifosfamide results in decreased expression of NIN mRNA CTD PMID:25596134 NCBI chr 6:94,261,382...94,363,679
Ensembl chr 6:94,263,206...94,363,610 		JBrowse link
G Nos1 nitric oxide synthase 1 increases activity
multiple interactions 		EXP Ifosfamide results in increased activity of NOS1 protein
morin inhibits the reaction [Ifosfamide results in increased activity of NOS1 protein] 		CTD PMID:31722249 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression 		EXP Carnitine inhibits the reaction [Ifosfamide results in increased expression of NOS2 mRNA] CTD PMID:23213347 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases expression ISO Ifosfamide results in increased expression of NPY1R mRNA CTD PMID:25596134 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Ifosfamide results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity 		ISO [Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Ifosfamide binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein] CTD PMID:18839173 PMID:20041327 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nrep neuronal regeneration related protein affects expression ISO Ifosfamide affects the expression of NREP mRNA CTD PMID:25596134 NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742 		JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO Ifosfamide results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:53,701,496...53,715,260
Ensembl chr19:70,593,274...70,613,197 		JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Ifosfamide results in decreased expression of NUAK1 mRNA CTD PMID:25596134 NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:21,217,681...21,289,354 		JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression ISO Ifosfamide results in decreased expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr19:64,380,336...64,409,165
Ensembl chr19:64,401,173...64,409,162 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO Ifosfamide results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,845,141...27,895,404 		JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO Ifosfamide results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:241,741,083...241,807,824 		JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO Ifosfamide results in decreased expression of PDE8A mRNA CTD PMID:25596134 NCBI chr 1:144,575,203...144,698,216
Ensembl chr 1:144,575,428...144,698,215 		JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Ifosfamide results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:78,777,436...78,892,370
Ensembl chr11:78,777,419...78,864,329 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO Ifosfamide results in decreased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO Ifosfamide results in increased expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO Ifosfamide results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621 		JBrowse link
G Pidd1 p53-induced death domain protein 1 decreases expression ISO Ifosfamide results in decreased expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:205,966,392...205,972,359
Ensembl chr 1:205,966,392...205,971,600 		JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression
multiple interactions 		ISO Ifosfamide affects the expression of PLAUR protein
[Ifosfamide co-treated with IFNA2] results in decreased expression of PLAUR protein; [Ifosfamide co-treated with IFNB1] results in decreased expression of PLAUR protein 		CTD PMID:15659795 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130 		JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 increases expression ISO Ifosfamide results in increased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:182,430,193...182,478,649
Ensembl chr 3:182,430,193...182,478,649 		JBrowse link
G Podxl podocalyxin-like decreases expression ISO Ifosfamide results in decreased expression of PODXL mRNA CTD PMID:25596134 NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO POR promotes the reaction [CYP2B6 results in increased susceptibility to Ifosfamide]; POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide] CTD PMID:9766669 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO Ifosfamide affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppfibp1 PPFIA binding protein 1 increases expression ISO Ifosfamide results in increased expression of PPFIBP1 mRNA CTD PMID:25596134 NCBI chr 4:181,538,249...181,682,079
Ensembl chr 4:181,539,450...181,682,076 		JBrowse link
G Ppig peptidylprolyl isomerase G decreases expression ISO Ifosfamide results in decreased expression of PPIG mRNA CTD PMID:25596134 NCBI chr 3:54,484,023...54,512,929
Ensembl chr 3:74,891,846...74,920,750 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D decreases expression ISO Ifosfamide results in decreased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO Ifosfamide results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012 		JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO Ifosfamide results in decreased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088 		JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 affects expression ISO Ifosfamide affects the expression of PRKAB1 mRNA CTD PMID:25596134 NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482 		JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 affects expression ISO Ifosfamide affects the expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:187,945,982...187,961,608 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Ifosfamide results in increased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693 		JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO Ifosfamide results in decreased expression of PSPC1 mRNA CTD PMID:25596134 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:34,967,477...35,026,828 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression 		EXP etoricoxib inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]; Indomethacin inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]; Pentoxifylline inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]; Thalidomide inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein] CTD PMID:17638016 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Ifosfamide results in increased expression of PYCR1 mRNA CTD PMID:25596134 NCBI chr10:106,416,056...106,420,982
Ensembl chr10:106,412,576...106,423,393 		JBrowse link
G Pygl glycogen phosphorylase L decreases expression ISO Ifosfamide results in decreased expression of PYGL mRNA CTD PMID:25596134 NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269 		JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO Ifosfamide results in increased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO Ifosfamide results in increased expression of RFFL mRNA CTD PMID:25596134 NCBI chr10:68,238,273...68,301,225
Ensembl chr10:68,238,273...68,321,902 		JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO Ifosfamide results in increased expression of RIT1 mRNA CTD PMID:25596134 NCBI chr 2:176,478,616...176,493,269
Ensembl chr 2:176,478,596...176,494,684 		JBrowse link
G Rlf RLF zinc finger increases expression ISO Ifosfamide results in increased expression of RLF mRNA CTD PMID:25596134 NCBI chr 5:139,996,782...140,052,419
Ensembl chr 5:139,996,782...140,052,419 		JBrowse link
G Rnf121 ring finger protein 121 decreases expression ISO Ifosfamide results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 1:156,377,368...156,439,936
Ensembl chr 1:165,789,360...165,858,884 		JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Ifosfamide results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:58,049,858...58,076,264 		JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Ifosfamide results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:76,443,658...76,448,593
Ensembl chr12:33,713,661...33,714,130
Ensembl chr 8:33,713,661...33,714,130 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases expression ISO Ifosfamide results in decreased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670 		JBrowse link
G Rrp12 ribosomal RNA processing 12 increases expression ISO Ifosfamide results in increased expression of RRP12 mRNA CTD PMID:25596134 NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:250,621,707...250,655,318 		JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 decreases expression ISO Ifosfamide results in decreased expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:38,500,709...38,520,715
Ensembl chr12:38,500,770...38,520,707 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 affects expression ISO Ifosfamide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:3,261,656...3,265,548 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Ifosfamide affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of SARS1 mRNA CTD PMID:25596134 NCBI chr 2:198,753,673...198,769,411
Ensembl chr 2:198,753,675...198,769,365 		JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO Ifosfamide results in increased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr 1:91,903,297...91,906,565
Ensembl chr 1:91,891,814...91,907,001 		JBrowse link
G Sesn1 sestrin 1 increases expression ISO Ifosfamide results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:46,876,918...46,970,010
Ensembl chr20:46,876,895...46,970,010 		JBrowse link
G Sfn stratifin increases expression ISO Ifosfamide results in increased expression of SFN mRNA CTD PMID:25596134 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO Ifosfamide results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:79,230,371...79,274,620 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 increases expression ISO Ifosfamide results in increased expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:145,063,857...145,081,873 		JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 decreases expression ISO Ifosfamide results in decreased expression of SIPA1L2 mRNA CTD PMID:25596134 NCBI chr19:70,287,134...70,437,810
Ensembl chr19:70,287,147...70,437,773 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor increases expression ISO Ifosfamide results in increased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr 6:137,526,416...137,530,790
Ensembl chr 6:137,526,031...137,530,790 		JBrowse link
G Slc12a8 solute carrier family 12, member 8 decreases expression ISO Ifosfamide results in decreased expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:80,622,000...80,771,674
Ensembl chr11:80,622,000...80,771,659 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO Ifosfamide results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 decreases expression EXP Ifosfamide results in decreased expression of SLC22A5 mRNA; Ifosfamide results in decreased expression of SLC22A5 protein CTD PMID:22701146 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression ISO Ifosfamide results in increased expression of SLC25A20 mRNA CTD PMID:25596134 NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Ifosfamide results in increased expression of SLC2A1 mRNA CTD PMID:25596134 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Ifosfamide results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO Ifosfamide results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Ifosfamide results in increased expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:66,843,808...66,872,412 		JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO Ifosfamide results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr11:44,336,818...44,409,127
Ensembl chr11:44,377,976...44,409,127 		JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Ifosfamide results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:165,642,851...165,654,225 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Ifosfamide results in increased expression of SQSTM1 mRNA CTD PMID:25596134 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 decreases expression ISO Ifosfamide results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr14:32,400,603...32,414,987
Ensembl chr14:32,400,603...32,415,117 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Ifosfamide results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765 		JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO Ifosfamide results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651 		JBrowse link
G Taldo1 transaldolase 1 increases expression ISO Ifosfamide results in increased expression of TALDO1 mRNA CTD PMID:25596134 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535 		JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO Ifosfamide results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 2:62,095,978...62,114,802
Ensembl chr 2:62,087,763...62,114,802 		JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression ISO Ifosfamide results in increased expression of TBXAS1 mRNA CTD PMID:25596134 NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969 		JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Ifosfamide results in decreased expression of TFAP2A mRNA CTD PMID:25596134 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219 		JBrowse link
G Thbs2 thrombospondin 2 decreases expression ISO Ifosfamide results in decreased expression of THBS2 mRNA CTD PMID:25596134 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Ifosfamide results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:161,613,306...161,632,229 		JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b decreases expression ISO Ifosfamide results in decreased expression of TIMM17B mRNA CTD PMID:25596134 NCBI chr  X:17,268,257...17,275,424
Ensembl chr  X:17,268,257...17,275,563 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO Ifosfamide results in increased expression of TLR4 mRNA CTD PMID:25596134 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tmem94 transmembrane protein 94 decreases expression ISO Ifosfamide results in decreased expression of TMEM94 mRNA CTD PMID:25596134 NCBI chr10:100,991,523...101,027,046
Ensembl chr10:101,490,481...101,525,975 		JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 decreases expression ISO Ifosfamide results in decreased expression of TMTC2 mRNA CTD PMID:25596134 NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:42,280,746...42,693,350 		JBrowse link
G Tnf tumor necrosis factor increases secretion
increases expression
multiple interactions 		EXP Ifosfamide results in increased secretion of TNF protein
Ifosfamide results in increased expression of TNF protein
morin inhibits the reaction [Ifosfamide results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Ifosfamide results in increased secretion of TNF protein] 		CTD PMID:17481685 PMID:31722249 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip8 TNF alpha induced protein 8 increases expression ISO Ifosfamide results in increased expression of TNFAIP8 mRNA CTD PMID:25596134 NCBI chr18:45,370,334...45,486,036
Ensembl chr18:45,370,406...45,486,036 		JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Ifosfamide results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339 		JBrowse link
G Top1 DNA topoisomerase I increases expression ISO Ifosfamide results in increased expression of TOP1 mRNA CTD PMID:25596134 NCBI chr 3:169,713,195...169,796,330
Ensembl chr 3:169,713,130...169,796,327 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO TOP2A results in decreased susceptibility to [Carboplatin co-treated with Etoposide co-treated with Ifosfamide] CTD PMID:11325482 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Tp53 tumor protein p53 affects activity
multiple interactions
increases expression 		ISO
EXP 		Ifosfamide affects the activity of TP53 protein
morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein] 		CTD PMID:25596134 PMID:31722249 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Ifosfamide results in increased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Ifosfamide results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression ISO Ifosfamide results in increased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:40,826,251...40,840,169
Ensembl chr12:40,825,851...40,841,320 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO Ifosfamide results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:46,928,273...46,930,766
Ensembl chr12:46,928,273...46,930,766 		JBrowse link
G Tspan12 tetraspanin 12 decreases expression ISO Ifosfamide results in decreased expression of TSPAN12 mRNA CTD PMID:25596134 NCBI chr 4:51,279,562...51,355,030
Ensembl chr 4:51,279,563...51,355,030 		JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Ifosfamide results in increased expression of TXN mRNA CTD PMID:25596134 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Ifosfamide results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 increases expression ISO Ifosfamide results in increased expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr20:10,983,322...11,005,060
Ensembl chr20:10,983,325...11,005,187 		JBrowse link
G Unkl unk like zinc finger increases expression ISO Ifosfamide results in increased expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,710,627...14,756,725
Ensembl chr10:14,710,563...14,756,724 		JBrowse link
G Usp3 ubiquitin specific peptidase 3 increases expression ISO Ifosfamide results in increased expression of USP3 mRNA CTD PMID:25596134 NCBI chr 8:75,973,278...76,049,151
Ensembl chr 8:75,974,615...76,049,153 		JBrowse link
G Vars1 valyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of VARS1 mRNA CTD PMID:25596134 NCBI chr20:3,810,427...3,825,193
Ensembl chr20:3,810,429...3,824,951 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression 		ISO IFNA2 promotes the reaction [Ifosfamide results in decreased expression of VEGFA protein]; IFNB1 promotes the reaction [Ifosfamide results in decreased expression of VEGFA protein] CTD PMID:15659795 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645 		JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO Ifosfamide results in decreased expression of WWC2 mRNA CTD PMID:25596134 NCBI chr16:44,258,372...44,421,815
Ensembl chr16:50,991,096...51,154,526 		JBrowse link
G Xbp1 X-box binding protein 1 affects activity ISO Ifosfamide affects the activity of XBP1 protein CTD PMID:25596134 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO Ifosfamide results in increased expression of XPC mRNA CTD PMID:25596134 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305 		JBrowse link
G Yeats2 YEATS domain containing 2 affects expression ISO Ifosfamide affects the expression of YEATS2 mRNA CTD PMID:25596134 NCBI chr11:94,247,538...94,333,652
Ensembl chr11:94,247,538...94,333,292 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO Ifosfamide results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:117,034,517...117,066,141
Ensembl chr 2:117,034,517...117,065,294 		JBrowse link
mechlorethamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression 		EXP Valproic Acid promotes the reaction [Mechlorethamine results in increased expression of AGTR1A mRNA] CTD PMID:28184907 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Mechlorethamine results in increased expression of AIFM1 mRNA CTD PMID:17107856 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO Mechlorethamine results in increased expression of AMPD3 mRNA CTD PMID:17107856 NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608 		JBrowse link
G Apcs amyloid P component, serum increases expression EXP Mechlorethamine results in increased expression of APCS mRNA CTD PMID:26273949 NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824 		JBrowse link
G Apoe apolipoprotein E multiple interactions
increases expression 		EXP Valproic Acid promotes the reaction [Mechlorethamine results in increased expression of APOE mRNA] CTD PMID:26273949 PMID:28184907 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Arg1 arginase 1 increases expression EXP Mechlorethamine results in increased expression of ARG1 protein CTD PMID:38513841 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Arl11 ARF like GTPase 11 multiple interactions
increases expression 		ISO NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of ARL11 protein] CTD PMID:35998709 NCBI chr15:39,659,404...39,661,651
Ensembl chr15:39,656,050...39,664,105 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO Mechlorethamine results in decreased expression of ATP1A2 mRNA CTD PMID:17107856 NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Mechlorethamine results in increased expression of BAK1 protein CTD PMID:22285227 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Mechlorethamine results in increased expression of and results in decreased localization of BAX protein; Mechlorethamine results in increased expression of and results in increased activity of BAX protein CTD PMID:16738803 PMID:22285227 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Mechlorethamine results in decreased expression of BCL2 protein CTD PMID:16738803 PMID:22285227 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Mechlorethamine results in decreased expression of CALM3 mRNA CTD PMID:17107856 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960 		JBrowse link
G Casp2 caspase 2 increases activity ISO Mechlorethamine results in increased activity of CASP2 protein CTD PMID:16738803 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions 		ISO Mechlorethamine results in increased activity of CASP3 protein
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein] 		CTD PMID:23649643 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions 		ISO Mechlorethamine results in increased activity of CASP9 protein
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein]; Mechlorethamine results in increased cleavage of and results in increased activity of CASP9 protein 		CTD PMID:16738803 PMID:22285227 PMID:23649643 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Mechlorethamine results in increased expression of CCL2 mRNA CTD PMID:26273949 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP Mechlorethamine results in increased expression of CCL5 mRNA CTD PMID:26273949 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP Mechlorethamine results in increased expression of CCN2 mRNA; Mechlorethamine results in increased expression of CCN2 protein CTD PMID:20883710 PMID:26273949 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
increases stability 		ISO Mechlorethamine results in decreased activity of [CCNA2 protein binds to CDK2 protein]; Mechlorethamine results in increased expression of and results in increased activity of [CDK2 protein binds to CCNA2 protein]; Pentoxifylline inhibits the reaction [Mechlorethamine results in increased activity of [CCNA2 protein binds to CDK2 protein]]
Mechlorethamine results in increased stability of CCNA2 protein 		CTD PMID:8463339 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb1 cyclin B1 decreases activity
multiple interactions 		ISO Mechlorethamine results in decreased activity of CCNB1 protein
Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]; Pentoxifylline inhibits the reaction [Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]] 		CTD PMID:8463339 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
increases expression 		EXP Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of CCR2 mRNA]
Mechlorethamine results in increased expression of CCR2 mRNA; Mechlorethamine results in increased expression of CCR2 protein 		CTD PMID:26273949 PMID:28184907 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression EXP Mechlorethamine results in increased expression of CCR5 mRNA CTD PMID:26273949 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd163 CD163 molecule increases expression
multiple interactions 		EXP
ISO 		Mechlorethamine results in increased expression of CD163 protein
NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of CD163 protein] 		CTD PMID:26273949 PMID:35998709 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146 		JBrowse link
G Cd68 Cd68 molecule increases expression EXP Mechlorethamine results in increased expression of CD68 protein CTD PMID:26273949 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases stability
decreases activity 		ISO Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]; Pentoxifylline inhibits the reaction [Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]]
Mechlorethamine results in increased stability of CDK1 protein modified form
Mechlorethamine results in decreased activity of CDK1 protein 		CTD PMID:8463339 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk2 cyclin dependent kinase 2 increases activity
multiple interactions 		ISO Mechlorethamine results in increased activity of CDK2 protein
Mechlorethamine results in decreased activity of [CCNA2 protein binds to CDK2 protein]; Mechlorethamine results in increased expression of and results in increased activity of [CDK2 protein binds to CCNA2 protein]; Pentoxifylline inhibits the reaction [Mechlorethamine results in increased activity of [CCNA2 protein binds to CDK2 protein]] 		CTD PMID:8463339 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cnr1 cannabinoid receptor 1 increases expression ISO Mechlorethamine results in increased expression of CNR1 protein CTD PMID:27125198 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Mechlorethamine results in increased expression of CNR2 protein CTD PMID:27125198 NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Mechlorethamine results in increased expression of CX3CL1 mRNA CTD PMID:26273949 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression
multiple interactions 		EXP Mechlorethamine results in increased expression of CX3CR1 mRNA; Mechlorethamine results in increased expression of CX3CR1 protein
Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of CX3CR1 mRNA] 		CTD PMID:26273949 PMID:28184907 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 affects response to substance ISO CXCR2 protein affects the susceptibility to Mechlorethamine CTD PMID:12753603 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Mechlorethamine results in increased expression of CXCR4 mRNA CTD PMID:17107856 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Mechlorethamine co-treated with Dimethyl Sulfoxide] results in increased phosphorylation of EIF4EBP1 protein; Mechlorethamine inhibits the reaction [Dimethyl Sulfoxide results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:36708981 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Ep300 E1A binding protein p300 increases expression EXP Mechlorethamine results in increased expression of EP300 protein CTD PMID:33971176 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO Mechlorethamine results in decreased expression of ERBB2 protein CTD PMID:17932452 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Faah fatty acid amide hydrolase increases expression ISO Mechlorethamine results in increased expression of FAAH protein CTD PMID:27125198 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Mechlorethamine results in increased expression of and affects the localization of FOS protein; Mechlorethamine results in increased phosphorylation of and results in increased expression of FOS protein
FOS protein affects the reaction [Mechlorethamine results in increased secretion of CXCL8 protein] 		CTD PMID:25891025 PMID:31639410 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO FOSB protein affects the reaction [Mechlorethamine results in increased secretion of CXCL8 protein]; FOSL1 protein affects the reaction [Mechlorethamine results in increased expression of and affects the localization of FOSB protein]; Mechlorethamine results in increased expression of and affects the localization of FOSB protein; U 0126 inhibits the reaction [Mechlorethamine results in increased expression of FOSB protein] CTD PMID:31639410 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO Mechlorethamine results in increased expression of FOSL1 protein
FOSL1 protein affects the reaction [Mechlorethamine results in increased expression of and affects the localization of FOSB protein]; FOSL1 protein affects the reaction [Mechlorethamine results in increased expression of CXCL8 mRNA]; FOSL1 protein affects the reaction [Mechlorethamine results in increased secretion of CXCL8 protein]; Mechlorethamine promotes the reaction [FOSL1 protein binds to JUN protein]; Mechlorethamine promotes the reaction [FOSL1 protein binds to JUNB protein]; Mechlorethamine promotes the reaction [FOSL1 protein binds to JUND protein]; Mechlorethamine results in increased expression of and affects the localization of FOSL1 protein; U 0126 inhibits the reaction [Mechlorethamine results in increased expression of FOSL1 protein] 		CTD PMID:31639410 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO Mechlorethamine results in increased expression of FOSL2 protein
FOSL2 protein affects the reaction [Mechlorethamine results in increased secretion of CXCL8 protein] 		CTD PMID:31639410 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406 		JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO Mechlorethamine results in increased expression of GDF9 mRNA CTD PMID:17107856 NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases response to substance
increases expression 		ISO GSTA2 protein results in decreased susceptibility to Mechlorethamine
Mechlorethamine results in increased expression of GSTA2 mRNA 		CTD PMID:15778998 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases response to substance EXP GSTA3 protein results in decreased susceptibility to Mechlorethamine CTD PMID:8044793 PMID:8860835 NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO
EXP 		Mechlorethamine results in increased expression of H2AX protein modified form CTD PMID:25891025 PMID:33971176 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions
increases expression 		EXP Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of HDAC2 protein] CTD PMID:28184907 PMID:33971176 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions 		EXP
ISO 		Mechlorethamine results in increased expression of HMOX1; Mechlorethamine results in increased expression of HMOX1 protein
NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of HMOX1]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of HMOX1 protein]
Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of HMOX1 protein]; Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of HMOX1 protein] 		CTD PMID:22981630 PMID:28184907 PMID:30060251 PMID:35998709 PMID:38513841 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions 		EXP Mechlorethamine results in increased expression of IL10 mRNA
Valproic Acid promotes the reaction [Mechlorethamine results in increased expression of IL10 mRNA] 		CTD PMID:26273949 PMID:28184907 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12a interleukin 12A increases expression EXP Mechlorethamine results in increased expression of IL12A mRNA CTD PMID:26273949 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B increases expression
multiple interactions 		EXP Mechlorethamine results in increased expression of IL12B mRNA
Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of IL12B mRNA] 		CTD PMID:28184907 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		ISO KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of IL1B mRNA] CTD PMID:34453837 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression 		ISO KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of IL33 mRNA] CTD PMID:34453837 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression 		ISO
EXP 		KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of IL6 mRNA]
Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of IL6 mRNA] 		CTD PMID:34453837 PMID:38513841 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itgam integrin subunit alpha M increases expression EXP Mechlorethamine results in increased expression of ITGAM protein CTD PMID:26273949 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 increases expression ISO Mechlorethamine results in increased expression of JAG1 mRNA CTD PMID:17107856 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation
multiple interactions
increases expression 		ISO Mechlorethamine results in increased phosphorylation of JUN protein
Mechlorethamine results in increased expression of and affects the localization of JUN protein
Mechlorethamine results in increased expression of JUN protein
Mechlorethamine promotes the reaction [FOSL1 protein binds to JUN protein]; U 0126 inhibits the reaction [Mechlorethamine results in increased expression of JUN protein] 		CTD PMID:25891025 PMID:31639410 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO Mechlorethamine promotes the reaction [FOSL1 protein binds to JUNB protein]; U 0126 inhibits the reaction [Mechlorethamine results in increased expression of JUNB protein]
Mechlorethamine results in increased expression of and affects the localization of JUNB protein 		CTD PMID:31639410 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO Mechlorethamine promotes the reaction [FOSL1 protein binds to JUND protein]; U 0126 inhibits the reaction [Mechlorethamine results in increased expression of JUND protein]
Mechlorethamine results in increased expression of and affects the localization of JUND protein 		CTD PMID:31639410 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects response to substance
multiple interactions 		ISO KIT gene mutant form affects the susceptibility to Mechlorethamine
KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of IL1B mRNA]; KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of IL33 mRNA]; KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of IL6 mRNA]; KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 mRNA]; KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of TNF mRNA] 		CTD PMID:34453837 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Lamc2 laminin subunit gamma 2 decreases expression
increases degradation 		ISO Mechlorethamine results in decreased expression of LAMC2 protein
Mechlorethamine results in increased degradation of LAMC2 protein 		CTD PMID:9504665 PMID:18095945 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions 		ISO Mechlorethamine results in increased phosphorylation of MAPK1 protein
Mechlorethamine results in increased phosphorylation of and affects the localization of MAPK1 protein 		CTD PMID:25891025 PMID:31639410 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions 		ISO Mechlorethamine results in increased phosphorylation of MAPK3 protein
Mechlorethamine results in increased phosphorylation of and affects the localization of MAPK3 protein 		CTD PMID:25891025 PMID:31639410 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Mechlorethamine results in increased phosphorylation of MAPK8 protein CTD PMID:25891025 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Mechlorethamine results in increased phosphorylation of MAPK9 protein CTD PMID:25891025 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mir106b microRNA 106b increases expression EXP Mechlorethamine results in increased expression of MIR106B mRNA CTD PMID:33971176 NCBI chr12:17,043,344...17,043,425 JBrowse link
G Mir125a microRNA 125a increases expression EXP Mechlorethamine results in increased expression of MIR125A mRNA CTD PMID:33971176 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759 		JBrowse link
G Mir125b1 microRNA 125b-1 increases expression EXP Mechlorethamine results in increased expression of MIR125B1 mRNA CTD PMID:33971176 NCBI chr 8:50,850,036...50,850,122
Ensembl chr 8:50,850,036...50,850,122 		JBrowse link
G Mir127 microRNA 127 increases expression EXP Mechlorethamine results in increased expression of MIR127 mRNA CTD PMID:33971176 NCBI chr 6:134,328,454...134,328,550
Ensembl chr 6:134,328,454...134,328,550 		JBrowse link
G Mir136 microRNA 136 increases expression EXP Mechlorethamine results in increased expression of MIR136 mRNA CTD PMID:33971176 NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:134,331,335...134,331,416 		JBrowse link
G Mir140 microRNA 140 increases expression EXP Mechlorethamine results in increased expression of MIR140 mRNA CTD PMID:33971176 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:52,375,293...52,375,391 		JBrowse link
G Mir141 microRNA 141 increases expression EXP Mechlorethamine results in increased expression of MIR141 mRNA CTD PMID:33971176 NCBI chr 4:159,209,525...159,209,618 JBrowse link
G Mir142 microRNA 142 increases expression EXP Mechlorethamine results in increased expression of MIR142 mRNA CTD PMID:33971176 NCBI chr10:73,055,104...73,055,190
Ensembl chr10:73,055,097...73,055,207 		JBrowse link
G Mir145 microRNA 145 increases expression EXP Mechlorethamine results in increased expression of MIR145 mRNA CTD PMID:33971176 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir146a microRNA 146a multiple interactions ISO [NR1H4 protein affects the susceptibility to Mechlorethamine] which affects the expression of MIR146 mRNA CTD PMID:35998709 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir146b microRNA 146b decreases expression EXP Mechlorethamine results in decreased expression of MIR146B mRNA CTD PMID:33971176 NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:255,144,860...255,144,947 		JBrowse link
G Mir148b microRNA 148b increases expression EXP Mechlorethamine results in increased expression of MIR148B mRNA CTD PMID:33971176 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:136,299,870...136,299,966 		JBrowse link
G Mir152 microRNA 152 increases expression EXP Mechlorethamine results in increased expression of MIR152 mRNA CTD PMID:33971176 NCBI chr10:82,329,383...82,329,467
Ensembl chr10:82,329,383...82,329,467 		JBrowse link
G Mir155 microRNA 155 increases expression ISO Mechlorethamine results in increased expression of MIR155 mRNA CTD PMID:35998709 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mir15a microRNA mir-15a increases expression EXP Mechlorethamine results in increased expression of MIR15A mRNA CTD PMID:33971176
G Mir15b microRNA 15b increases expression EXP Mechlorethamine results in increased expression of MIR15B mRNA CTD PMID:33971176 NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:155,555,178...155,555,275 		JBrowse link
G Mir16-2 microRNA 16-2 increases expression EXP Mechlorethamine results in increased expression of MIR16-2 mRNA CTD PMID:33971176 NCBI chr 2:155,555,327...155,555,421
Ensembl chr 2:155,555,327...155,555,421 		JBrowse link
G Mir17 microRNA 17 increases expression EXP Mechlorethamine results in increased expression of MIR17 mRNA CTD PMID:33971176 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:98,587,848...98,587,931 		JBrowse link
G Mir181a2 microRNA 181a-2 increases expression EXP Mechlorethamine results in increased expression of MIR181A2 mRNA CTD PMID:33971176 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:43,025,563...43,025,679 		JBrowse link
G Mir181b1 microRNA 181b-1 increases expression EXP Mechlorethamine results in increased expression of MIR181B1 mRNA CTD PMID:33971176 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:52,037,228...52,037,337 		JBrowse link
G Mir181c microRNA 181c increases expression EXP Mechlorethamine results in increased expression of MIR181C mRNA CTD PMID:33971176 NCBI chr19:40,888,291...40,888,396
Ensembl chr19:40,888,291...40,888,396 		JBrowse link
G Mir181d microRNA 181d increases expression EXP Mechlorethamine results in increased expression of MIR181D mRNA CTD PMID:33971176 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:40,888,474...40,888,556 		JBrowse link
G Mir182 microRNA 182 increases expression EXP Mechlorethamine results in increased expression of MIR182 mRNA CTD PMID:33971176 NCBI chr 4:59,752,246...59,752,307 JBrowse link
G Mir183 microRNA 183 increases expression EXP Mechlorethamine results in increased expression of MIR183 mRNA CTD PMID:33971176 NCBI chr 4:58,788,614...58,788,723 JBrowse link
G Mir186 microRNA 186 increases expression EXP Mechlorethamine results in increased expression of MIR186 mRNA CTD PMID:33971176 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:249,241,650...249,241,735 		JBrowse link
G Mir195 microRNA 195 increases expression EXP Mechlorethamine results in increased expression of MIR195 mRNA CTD PMID:33971176 NCBI chr10:55,450,495...55,450,581
Ensembl chr10:55,450,495...55,450,581 		JBrowse link
G Mir19a microRNA 19a increases expression EXP Mechlorethamine results in increased expression of MIR19A mRNA CTD PMID:33971176 NCBI chr15:98,588,131...98,588,212
Ensembl chr15:98,588,131...98,588,212 		JBrowse link
G Mir19b1 microRNA 19b-1 increases expression EXP Mechlorethamine results in increased expression of MIR19B1 mRNA CTD PMID:33971176 NCBI chr15:98,588,433...98,588,519
Ensembl chr15:98,588,433...98,588,519 		JBrowse link
G Mir200a microRNA 200a increases expression EXP Mechlorethamine results in increased expression of MIR200A mRNA CTD PMID:33971176 NCBI chr 5:171,930,717...171,930,805 JBrowse link
G Mir200c microRNA 200c increases expression EXP Mechlorethamine results in increased expression of MIR200C mRNA CTD PMID:33971176 NCBI chr 4:159,209,965...159,210,033 JBrowse link
G Mir203 microRNA 203 increases expression EXP Mechlorethamine results in increased expression of MIR203 mRNA CTD PMID:33971176 NCBI chr 6:137,020,691...137,020,805 JBrowse link
G Mir205 microRNA 205 increases expression EXP Mechlorethamine results in increased expression of MIR205 mRNA CTD PMID:33971176 NCBI chr13:107,564,535...107,564,642 JBrowse link
G Mir20a microRNA 20a increases expression EXP Mechlorethamine results in increased expression of MIR20A mRNA CTD PMID:33971176 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:98,588,303...98,588,387 		JBrowse link
G Mir20b microRNA 20b increases expression EXP Mechlorethamine results in increased expression of MIR20B mRNA CTD PMID:33971176 NCBI chr  X:137,343,197...137,343,268 JBrowse link
G Mir21 microRNA 21 increases expression EXP Mechlorethamine results in increased expression of MIR21 mRNA CTD PMID:33971176 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mir221 microRNA 221 increases expression EXP Mechlorethamine results in increased expression of MIR221 mRNA CTD PMID:33971176 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:6,023,182...6,023,290 		JBrowse link
G Mir222 microRNA 222 increases expression EXP Mechlorethamine results in increased expression of MIR222 mRNA CTD PMID:33971176 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:6,022,621...6,022,723 		JBrowse link
G Mir223 microRNA 223 multiple interactions ISO [NR1H4 protein affects the susceptibility to Mechlorethamine] which affects the expression of MIR223 mRNA CTD PMID:35998709 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:65,151,383...65,151,492 		JBrowse link
G Mir23b microRNA 23b increases expression EXP Mechlorethamine results in increased expression of MIR23B mRNA CTD PMID:33971176 NCBI chr17:1,819,386...1,819,482 JBrowse link
G Mir26a1 microRNA 26a-1 increases expression EXP Mechlorethamine results in increased expression of MIR26A1 mRNA CTD PMID:33971176 NCBI chr 8:127,633,048...127,633,137
Ensembl chr 8:127,633,048...127,633,137 		JBrowse link
G Mir27a microRNA 27a increases expression EXP Mechlorethamine results in increased expression of MIR27A mRNA CTD PMID:33971176 NCBI chr19:40,859,603...40,859,689 JBrowse link
G Mir27b microRNA 27b increases expression EXP Mechlorethamine results in increased expression of MIR27B mRNA CTD PMID:33971176 NCBI chr17:1,819,147...1,819,243 JBrowse link
G Mir291a microRNA 291a increases expression EXP Mechlorethamine results in increased expression of MIR291A mRNA CTD PMID:33971176 NCBI chr 1:65,964,350...65,964,431 JBrowse link
G Mir29a microRNA 29a increases expression EXP Mechlorethamine results in increased expression of MIR29A mRNA CTD PMID:33971176 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir30a microRNA 30a increases expression EXP Mechlorethamine results in increased expression of MIR30A mRNA CTD PMID:33971176 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011 		JBrowse link
G Mir30b microRNA 30b increases expression EXP Mechlorethamine results in increased expression of MIR30B mRNA CTD PMID:33971176 NCBI chr 7:102,021,543...102,021,629 JBrowse link
G Mir30c1 microRNA 30c-1 increases expression EXP Mechlorethamine results in increased expression of MIR30C1 mRNA CTD PMID:33971176 NCBI chr 5:139,634,455...139,634,543 JBrowse link
G Mir30d microRNA 30d increases expression EXP Mechlorethamine results in increased expression of MIR30D mRNA CTD PMID:33971176 NCBI chr 7:102,025,345...102,025,426 JBrowse link
G Mir30e microRNA 30e increases expression EXP Mechlorethamine results in increased expression of MIR30E mRNA CTD PMID:33971176 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:139,637,450...139,637,541 		JBrowse link
G Mir320a microRNA 320a increases expression EXP Mechlorethamine results in increased expression of MIR320A mRNA CTD PMID:33971176 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169 		JBrowse link
G Mir322 microRNA 322 increases expression EXP Mechlorethamine results in increased expression of MIR322 mRNA CTD PMID:33971176 NCBI chr  X:137,726,147...137,726,241 JBrowse link
G Mir325 microRNA 325 increases expression EXP Mechlorethamine results in increased expression of MIR325 mRNA CTD PMID:33971176 NCBI chr  X:70,457,918...70,458,015 JBrowse link
G Mir327 microRNA 327 increases expression EXP Mechlorethamine results in increased expression of MIR327 mRNA CTD PMID:33971176 NCBI chr20:13,161,640...13,161,733 JBrowse link
G Mir34c microRNA 34c increases expression EXP Mechlorethamine results in increased expression of MIR34C mRNA CTD PMID:33971176 NCBI chr 8:60,306,091...60,306,167 JBrowse link
G Mir351 microRNA 351 increases expression EXP Mechlorethamine results in increased expression of MIR351 mRNA CTD PMID:33971176 NCBI chr  X:137,725,116...137,725,196 JBrowse link
G Mir374b microRNA 374b increases expression EXP Mechlorethamine results in increased expression of MIR374B mRNA CTD PMID:33971176 NCBI chr  X:72,657,495...72,657,562 JBrowse link
G Mir381 microRNA 381 increases expression EXP Mechlorethamine results in increased expression of MIR381 mRNA CTD PMID:33971176 NCBI chr 6:134,562,381...134,562,441 JBrowse link
G Mir384 microRNA 384 increases expression EXP Mechlorethamine results in increased expression of MIR384 mRNA CTD PMID:33971176 NCBI chr  X:70,425,293...70,425,375 JBrowse link
G Mir410 microRNA 410 increases expression EXP Mechlorethamine results in increased expression of MIR410 mRNA CTD PMID:33971176 NCBI chr 6:134,579,763...134,579,838
Ensembl chr 6:134,579,759...134,579,839 		JBrowse link
G Mir429 microRNA 429 increases expression EXP Mechlorethamine results in increased expression of MIR429 mRNA CTD PMID:33971176 NCBI chr 5:171,929,682...171,929,766 JBrowse link
G Mir449a microRNA 449a increases expression EXP Mechlorethamine results in increased expression of MIR449A mRNA CTD PMID:33971176 NCBI chr 2:46,403,910...46,404,000
Ensembl chr 2:46,403,910...46,404,000 		JBrowse link
G Mir495 microRNA 495 increases expression EXP Mechlorethamine results in increased expression of MIR495 mRNA CTD PMID:33971176 NCBI chr 6:128,732,650...128,732,729
Ensembl chr 6:134,554,055...134,554,134 		JBrowse link
G Mir497 microRNA 497 increases expression EXP Mechlorethamine results in increased expression of MIR497 mRNA CTD PMID:33971176 NCBI chr10:55,450,171...55,450,239
Ensembl chr10:55,450,162...55,450,241 		JBrowse link
G Mir673 microRNA 673 increases expression EXP Mechlorethamine results in increased expression of MIR673 mRNA CTD PMID:33971176 NCBI chr 6:128,524,261...128,524,343
Ensembl chr 6:134,306,500...134,306,582 		JBrowse link
G Mir743b microRNA 743b increases expression EXP Mechlorethamine results in increased expression of MIR743B mRNA CTD PMID:33971176 NCBI chr  X:150,444,578...150,444,654 JBrowse link
G Mir878 microRNA 878 increases expression EXP Mechlorethamine results in increased expression of MIR878 mRNA CTD PMID:33971176 NCBI chr  X:145,432,857...145,432,933 JBrowse link
G Mir9-1 microRNA 9-1 increases expression EXP Mechlorethamine results in increased expression of MIR9-1 mRNA CTD PMID:33971176 NCBI chr 2:175,974,971...175,975,059 JBrowse link
G Mir93 microRNA 93 increases expression EXP Mechlorethamine results in increased expression of MIR93 mRNA CTD PMID:33971176 NCBI chr12:22,156,844...22,156,930 JBrowse link
G Mir98 microRNA 98 increases expression EXP Mechlorethamine results in increased expression of MIR98 mRNA CTD PMID:33971176 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:24,460,648...24,460,755 		JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP Mechlorethamine results in increased expression of MIRLET7B mRNA CTD PMID:33971176 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:118,684,038...118,684,122 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression EXP Mechlorethamine results in increased expression of MIRLET7C1 mRNA CTD PMID:33971176 NCBI chr11:29,688,112...29,688,205
Ensembl chr11:29,688,107...29,688,214 		JBrowse link
G Mirlet7i microRNA let-7i increases expression EXP Mechlorethamine results in increased expression of MIRLET7I mRNA CTD PMID:33971176 NCBI chr 7:58,642,485...58,642,569 JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression EXP Mechlorethamine results in increased expression of MMP10 mRNA CTD PMID:26273949 NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions 		ISO
EXP 		Mechlorethamine results in increased expression of MMP9; Mechlorethamine results in increased expression of MMP9 protein
Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of MMP9 mRNA]
Mechlorethamine results in increased expression of MMP9 mRNA; Mechlorethamine results in increased expression of MMP9 protein
MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of MMP9]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of MMP9 protein] 		CTD PMID:20883710 PMID:24631667 PMID:25891025 PMID:26273949 PMID:28184907 More... NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein decreases expression ISO Mechlorethamine results in decreased expression of MOBP mRNA CTD PMID:17107856 NCBI chr 8:128,747,117...128,777,238
Ensembl chr 8:128,747,232...128,777,936 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases response to substance 		ISO MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of MMP9]; MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of NOS2]; MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of PTGS2]
MPO protein results in increased susceptibility to Mechlorethamine 		CTD PMID:24631667 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression
multiple interactions 		EXP
ISO 		Mechlorethamine results in increased expression of MRC1 protein
SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of MRC1 protein] 		CTD PMID:26273949 PMID:30060251 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Msh2 mutS homolog 2 affects response to substance ISO MSH2 protein affects the susceptibility to Mechlorethamine CTD PMID:12185594 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Nckap1 NCK-associated protein 1 decreases expression ISO Mechlorethamine results in decreased expression of NCKAP1 mRNA CTD PMID:17107856 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797 		JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Mechlorethamine results in decreased expression of NDRG2 mRNA CTD PMID:17107856 NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects response to substance
decreases response to substance 		ISO NFE2L2 gene mutant form affects the susceptibility to Mechlorethamine
NFE2L2 protein results in decreased susceptibility to Mechlorethamine 		CTD PMID:20932822 PMID:26454883 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nmu neuromedin U increases expression ISO Mechlorethamine results in increased expression of NMU mRNA CTD PMID:17107856 NCBI chr14:32,198,789...32,226,397
Ensembl chr14:32,198,943...32,226,632 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions 		ISO
EXP 		Mechlorethamine results in increased expression of NOS2; Mechlorethamine results in increased expression of NOS2 protein
Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of NOS2 protein]; Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of NOS2 mRNA]
Mechlorethamine results in increased expression of NOS2 mRNA; Mechlorethamine results in increased expression of NOS2 protein
MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of NOS2]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of NOS2 protein] 		CTD PMID:20883710 PMID:24631667 PMID:25891025 PMID:26273949 PMID:28184907 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
affects response to substance 		ISO [NR1H4 protein affects the susceptibility to Mechlorethamine] which affects the expression of MIR146 mRNA; [NR1H4 protein affects the susceptibility to Mechlorethamine] which affects the expression of MIR223 mRNA; NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of ARL11 protein]; NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of CD163 protein]; NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of HMOX1]; NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of PTGS2 protein]; NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of STAT6 protein] CTD PMID:35998709 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
multiple interactions 		EXP Mechlorethamine results in increased expression of PCNA; Mechlorethamine results in increased expression of PCNA protein
Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of PCNA protein] 		CTD PMID:22981630 PMID:28184907 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Mechlorethamine results in increased expression of PDCD4 mRNA CTD PMID:17107856 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 increases expression ISO Mechlorethamine results in increased expression of PDPK1 protein modified form CTD PMID:25891025 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO Mechlorethamine results in decreased expression of PLP1 mRNA CTD PMID:17107856 NCBI chr  X:104,933,921...104,993,317
Ensembl chr  X:104,975,780...104,993,314 		JBrowse link
G Polr2j RNA polymerase II subunit J decreases expression ISO Mechlorethamine results in decreased expression of POLR2J mRNA CTD PMID:17107856 NCBI chr12:20,543,038...20,548,590
Ensembl chr12:26,179,649...26,185,201 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO Mechlorethamine results in increased expression of PPARA protein CTD PMID:27125198 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 increases expression ISO Mechlorethamine results in increased expression of PSMD11 mRNA CTD PMID:17107856 NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234 		JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 increases expression ISO Mechlorethamine results in increased expression of PSMD7 mRNA CTD PMID:17107856 NCBI chr19:35,494,317...35,501,605
Ensembl chr19:52,404,032...52,417,871 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions 		ISO
EXP 		Mechlorethamine results in increased expression of PTGS2; Mechlorethamine results in increased expression of PTGS2 mRNA; Mechlorethamine results in increased expression of PTGS2 protein
Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 protein]; Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 mRNA]
KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of PTGS2 mRNA]; MPO gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of PTGS2]; NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of PTGS2 protein] 		CTD PMID:20883710 PMID:24631667 PMID:25891025 PMID:26273949 PMID:28184907 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rad51 RAD51 recombinase increases expression ISO Mechlorethamine results in increased expression of RAD51 protein CTD PMID:25891025 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO Mechlorethamine affects the reaction [Dimethyl Sulfoxide affects the phosphorylation of RPS6 protein]
[Dimethyl Sulfoxide co-treated with Mechlorethamine] results in increased phosphorylation of RPS6 protein; Mechlorethamine inhibits the reaction [Dimethyl Sulfoxide results in increased phosphorylation of RPS6 protein] 		CTD PMID:36708981 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 increases expression ISO Mechlorethamine results in increased expression of RPTOR protein CTD PMID:36708981 NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413 		JBrowse link
G Sem1 SEM1 26S proteasome subunit increases expression ISO Mechlorethamine results in increased expression of SEM1 mRNA CTD PMID:17107856 NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:35,638,306...35,658,462 		JBrowse link
G Sftpd surfactant protein D increases expression
increases response to substance
multiple interactions 		ISO Mechlorethamine results in increased expression of SFTPD protein
SFTPD gene mutant form results in increased susceptibility to Mechlorethamine
SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of CHIL3 protein]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of HMOX1 protein]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of MMP9 protein]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of MRC1 protein]; SFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of NOS2 protein] 		CTD PMID:30060251 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,080,567...17,094,036 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Mechlorethamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Snora36c small nucleolar RNA, H/ACA box 36C increases expression EXP Mechlorethamine results in increased expression of SNORA36C mRNA CTD PMID:33971176 NCBI chr18:45,952,021...45,952,079
Ensembl chr18:48,150,366...48,150,424 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions 		EXP Mechlorethamine results in increased expression of SOD2; Mechlorethamine results in increased expression of SOD2 protein
Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of SOD2 protein] 		CTD PMID:22981630 PMID:28184907 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
increases expression 		ISO NR1H4 protein affects the reaction [Mechlorethamine results in increased expression of STAT6 protein] CTD PMID:35998709 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Stk11 serine/threonine kinase 11 increases expression ISO Mechlorethamine results in increased expression of STK11 mRNA CTD PMID:17107856 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Mechlorethamine results in increased expression of TGFB1 protein CTD PMID:38513841 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions 		ISO
EXP 		Mechlorethamine results in increased expression of TNF mRNA; Mechlorethamine results in increased expression of TNF protein
Acetylcysteine inhibits the reaction [Mechlorethamine results in increased expression of TNF protein]
KIT gene mutant form inhibits the reaction [Mechlorethamine results in increased expression of TNF mRNA] 		CTD PMID:25891025 PMID:26243812 PMID:26273949 PMID:34453837 PMID:38513841 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A decreases expression ISO Mechlorethamine results in decreased expression of TNFRSF12A mRNA CTD PMID:17107856 NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
affects binding
decreases activity
increases stability
increases alkylation
affects response to substance
increases expression 		ISO Mechlorethamine results in increased phosphorylation of and results in increased expression of TRP53 protein
Mechlorethamine binds to TP53 protein
Mechlorethamine results in increased expression of and affects the localization of TP53 protein; Mechlorethamine results in increased phosphorylation of and results in increased acetylation of TP53 protein
Mechlorethamine results in decreased activity of TP53 protein
Mechlorethamine results in increased stability of TP53 protein
Mechlorethamine results in increased alkylation of TP53 protein
TRP53 affects the susceptibility to Mechlorethamine; TRP53 protein affects the susceptibility to Mechlorethamine
Mechlorethamine results in increased expression of TP53 protein 		CTD PMID:12185594 PMID:16738803 PMID:23845566 PMID:25891025 PMID:35312310 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases response to substance ISO TRPA1 protein results in increased susceptibility to Mechlorethamine CTD PMID:36693442 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325 		JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO Mechlorethamine results in decreased activity of TXN protein CTD PMID:26451472 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO
EXP 		[NADP co-treated with Mechlorethamine] results in decreased activity of TXNRD1 protein
[NADP co-treated with Mechlorethamine] promotes the reaction [TXNRD1 protein binds to TXNRD1 protein]; [NADP co-treated with Mechlorethamine] results in decreased activity of and results in increased alkylation of TXNRD1 protein 		CTD PMID:24274902 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Txnrd2 thioredoxin reductase 2 decreases activity ISO Mechlorethamine results in decreased activity of TXNRD2 protein CTD PMID:24274902 NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K increases expression ISO Mechlorethamine results in increased expression of UBE2K mRNA CTD PMID:17107856 NCBI chr14:43,011,681...43,077,825
Ensembl chr14:43,011,681...43,072,462 		JBrowse link
melphalan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects export ISO ABCC1 protein affects the export of Melphalan analog CTD PMID:11115505 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abhd17c abhydrolase domain containing 17C, depalmitoylase decreases expression ISO Melphalan results in decreased expression of ABHD17C mRNA CTD PMID:22363485 NCBI chr 1:147,493,755...147,534,715
Ensembl chr 1:147,493,753...147,534,715 		JBrowse link
G Abraxas1 abraxas 1, BRCA1 A complex subunit decreases expression ISO Melphalan results in decreased expression of ABRAXAS1 mRNA CTD PMID:22363485 NCBI chr14:9,100,650...9,115,012
Ensembl chr14:9,100,671...9,115,011 		JBrowse link
G Abt1 activator of basal transcription 1 increases expression ISO Melphalan results in increased expression of ABT1 mRNA CTD PMID:22363485 NCBI chr17:42,127,173...42,129,281
Ensembl chr17:42,127,202...42,130,684 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Melphalan results in increased expression of ACKR3 mRNA CTD PMID:22363485 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214 		JBrowse link
G Acvr1c activin A receptor type 1C decreases expression ISO Melphalan results in decreased expression of ACVR1C mRNA CTD PMID:22363485 NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:63,227,559...63,301,205 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor decreases expression ISO Melphalan results in decreased expression of AHRR mRNA CTD PMID:22363485 NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866 		JBrowse link
G Alad aminolevulinate dehydratase decreases activity ISO Melphalan results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041 		JBrowse link
G Ammecr1l AMMECR1 like increases expression ISO Melphalan results in increased expression of AMMECR1L mRNA CTD PMID:22363485 NCBI chr18:23,386,114...23,411,177
Ensembl chr18:23,661,341...23,685,649 		JBrowse link
G Ankar ankyrin and armadillo repeat containing decreases expression ISO Melphalan results in decreased expression of ANKAR mRNA CTD PMID:22363485 NCBI chr 9:48,141,534...48,215,400
Ensembl chr 9:55,633,566...55,707,369 		JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO Melphalan results in increased expression of ANKRD10 mRNA CTD PMID:22363485 NCBI chr16:84,566,021...84,591,849
Ensembl chr16:84,568,506...84,591,846 		JBrowse link
G Ankrd28 ankyrin repeat domain 28 decreases expression ISO Melphalan results in decreased expression of ANKRD28 mRNA CTD PMID:22363485 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,924,882...7,056,593 		JBrowse link
G Ankrd34a ankyrin repeat domain 34A decreases expression ISO Melphalan results in decreased expression of ANKRD34A mRNA CTD PMID:22363485 NCBI chr 2:186,818,496...186,823,921
Ensembl chr 2:186,817,216...186,824,467 		JBrowse link
G Ar androgen receptor decreases expression ISO Melphalan results in decreased expression of AR mRNA CTD PMID:22363485 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Arhgap12 Rho GTPase activating protein 12 decreases expression ISO Melphalan results in decreased expression of ARHGAP12 mRNA CTD PMID:22363485 NCBI chr17:56,284,282...56,397,630
Ensembl chr17:56,284,286...56,397,563 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Melphalan results in decreased expression of ARHGAP18 mRNA CTD PMID:22363485 NCBI chr 1:20,222,948...20,456,827
Ensembl chr 1:20,222,954...20,456,670 		JBrowse link
G Arhgap20 Rho GTPase activating protein 20 decreases expression ISO Melphalan results in decreased expression of ARHGAP20 mRNA CTD PMID:22363485 NCBI chr 8:60,970,480...61,055,199
Ensembl chr 8:60,970,475...61,055,198 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO Melphalan results in decreased expression of ARHGAP24 mRNA CTD PMID:22363485 NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO Melphalan results in decreased expression of ARHGAP42 mRNA CTD PMID:22363485 NCBI chr 8:14,436,478...14,666,588
Ensembl chr 8:14,419,256...14,666,385 		JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Melphalan results in increased expression of ARID5A mRNA CTD PMID:22363485 NCBI chr 9:46,030,513...46,058,729
Ensembl chr 9:46,030,548...46,045,363 		JBrowse link
G Atg16l1 autophagy related 16-like 1 increases expression ISO Melphalan results in increased expression of ATG16L1 mRNA CTD PMID:22363485 NCBI chr 9:95,869,839...95,905,354
Ensembl chr 9:95,869,865...95,905,357 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Melphalan results in decreased expression of ATP2B1 mRNA CTD PMID:22363485 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904 		JBrowse link
G Aurka aurora kinase A increases expression ISO Melphalan results in increased expression of AURKA protein CTD PMID:22025197 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Melphalan results in decreased expression of AURKB protein CTD PMID:22025197 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 increases expression ISO Melphalan results in increased expression of B3GNT2 mRNA CTD PMID:22363485 NCBI chr14:101,009,682...101,034,507
Ensembl chr14:100,967,131...101,043,412 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Melphalan results in increased expression of B3GNT5 mRNA CTD PMID:22363485 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:94,645,480...94,660,514 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Melphalan results in increased expression of BAK1 protein CTD PMID:22285227 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Melphalan results in increased expression of and results in decreased localization of BAX protein CTD PMID:22285227 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein CTD PMID:4672170 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Melphalan results in decreased expression of BCL2 protein CTD PMID:22285227 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Melphalan results in increased expression of BCL2A1 mRNA CTD PMID:22363485 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890 		JBrowse link
G Bicc1 BicC family RNA binding protein 1 decreases expression ISO Melphalan results in decreased expression of BICC1 mRNA CTD PMID:22363485 NCBI chr20:17,448,745...17,685,887
Ensembl chr20:17,448,765...17,685,885 		JBrowse link
G Bicdl2 BICD family like cargo adaptor 2 increases expression ISO Melphalan results in increased expression of BICDL2 mRNA CTD PMID:22363485 NCBI chr10:13,196,205...13,204,642
Ensembl chr10:13,195,913...13,204,642 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects response to substance
decreases expression
multiple interactions 		ISO BIRC5 protein affects the susceptibility to Melphalan
Melphalan results in decreased expression of BIRC5 protein
Nocodazole affects the reaction [BIRC5 protein affects the susceptibility to Melphalan]; Paclitaxel affects the reaction [BIRC5 protein affects the susceptibility to Melphalan] 		CTD PMID:16373717 PMID:22025197 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bnc2 basonuclin zinc finger protein 2 decreases expression ISO Melphalan results in decreased expression of BNC2 mRNA CTD PMID:22363485 NCBI chr 5:98,679,071...99,016,044
Ensembl chr 5:103,724,934...104,125,428 		JBrowse link
G Btbd8 BTB domain containing 8 decreases expression ISO Melphalan results in decreased expression of BTBD8 mRNA CTD PMID:22363485 NCBI chr14:2,410,093...2,483,114
Ensembl chr14:2,410,093...2,479,202 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Melphalan results in increased expression of BTG2 mRNA CTD PMID:22363485 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690 		JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression ISO Melphalan results in decreased expression of CABLES1 mRNA CTD PMID:22363485 NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956 		JBrowse link
G Casp3 caspase 3 increases activity ISO Melphalan results in increased activity of CASP3 protein CTD PMID:16951922 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Melphalan results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:22285227 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases activity ISO Melphalan results in decreased activity of CAT protein CTD PMID:19162187 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO Melphalan results in decreased expression of CC2D2A mRNA CTD PMID:22363485 NCBI chr14:71,563,835...71,648,352
Ensembl chr14:71,563,835...71,648,331 		JBrowse link
G Ccdc110 coiled-coil domain containing 110 decreases expression ISO Melphalan results in decreased expression of CCDC110 mRNA CTD PMID:22363485 NCBI chr16:46,315,745...46,337,050
Ensembl chr16:53,047,965...53,069,777 		JBrowse link
G Ccdc171 coiled-coil domain containing 171 decreases expression ISO Melphalan results in decreased expression of CCDC171 mRNA CTD PMID:22363485 NCBI chr 5:97,919,965...98,403,853
Ensembl chr 5:102,965,911...103,533,290 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Melphalan results in increased expression of CCL20 mRNA CTD PMID:22363485 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccnj cyclin J increases expression ISO Melphalan results in increased expression of CCNJ mRNA CTD PMID:22363485 NCBI chr 1:249,608,991...249,626,798
Ensembl chr 1:249,608,969...249,626,794 		JBrowse link
G Cd34 CD34 molecule multiple interactions ISO [Melphalan co-treated with Prednisolone] results in decreased expression of CD34 protein CTD PMID:10618687 NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315 		JBrowse link
G Cd59b CD59b molecule decreases lipidation EXP Melphalan results in decreased lipidation of CD59 protein CTD PMID:27931811 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Cda cytidine deaminase decreases response to substance ISO CDA protein results in decreased susceptibility to Melphalan CTD PMID:10830723 NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541 		JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Melphalan results in decreased expression of CDC14B mRNA CTD PMID:22363485 NCBI chr17:850,272...938,972
Ensembl chr17:850,390...971,164 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Melphalan results in decreased expression of CDC42EP3 mRNA CTD PMID:22363485 NCBI chr 6:21,463,081...21,483,553
Ensembl chr 6:21,461,762...21,508,540 		JBrowse link
G Cfap206 cilia and flagella associated protein 206 decreases expression ISO Melphalan results in decreased expression of CFAP206 mRNA CTD PMID:22363485 NCBI chr 5:49,254,399...49,299,145
Ensembl chr 5:54,050,701...54,095,383 		JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK1 protein CTD PMID:26208482 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Melphalan results in increased phosphorylation of CHEK2 protein CTD PMID:26208482 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex affects phosphorylation ISO Melphalan affects the phosphorylation of CHUK protein CTD PMID:19934314 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator decreases expression ISO Melphalan results in decreased expression of CIITA mRNA CTD PMID:22363485 NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 increases expression ISO Melphalan results in increased expression of CITED4 mRNA CTD PMID:22363485 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:139,531,584...139,533,361 		JBrowse link
G Cnksr3 Cnksr family member 3 decreases expression ISO Melphalan results in decreased expression of CNKSR3 mRNA CTD PMID:22363485 NCBI chr 1:45,904,581...45,996,921
Ensembl chr 1:45,904,581...45,996,921 		JBrowse link
G Cpne8 copine 8 decreases expression ISO Melphalan results in decreased expression of CPNE8 mRNA CTD PMID:22363485 NCBI chr 7:123,494,864...123,669,060
Ensembl chr 7:123,494,865...123,669,060 		JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO Melphalan results in decreased expression of CREB5 mRNA CTD PMID:22363485 NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793 		JBrowse link
G Cul3 cullin 3 increases expression ISO Melphalan results in increased expression of CUL3 mRNA CTD PMID:22363485 NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:89,040,987...89,118,427 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Melphalan results in decreased expression of CXCL12 mRNA; Melphalan results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP 		Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP 		Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Melphalan results in increased expression of CYP27B1 mRNA CTD PMID:22363485 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570 		JBrowse link
G Cyria CYFIP related Rac1 interactor A decreases expression ISO Melphalan results in decreased expression of CYRIA mRNA CTD PMID:22363485 NCBI chr 6:40,774,165...40,883,005
Ensembl chr 6:40,774,171...40,881,860 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit increases expression ISO Melphalan results in increased expression of DBF4 mRNA CTD PMID:22363485 NCBI chr 4:26,631,491...26,656,080
Ensembl chr 4:26,631,514...26,656,562 		JBrowse link
G Dcn decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926 		JBrowse link
G Dennd4c DENN domain containing 4C decreases expression ISO Melphalan results in decreased expression of DENND4C mRNA CTD PMID:22363485 NCBI chr 5:106,316,942...106,421,484
Ensembl chr 5:106,318,281...106,415,489 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 decreases expression ISO Melphalan results in decreased expression of DLG3 mRNA CTD PMID:22363485 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:69,900,003...69,950,696 		JBrowse link
G Dst dystonin decreases expression ISO Melphalan results in decreased expression of DST mRNA CTD PMID:22363485 NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533 		JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Melphalan results in increased expression of DUSP2 mRNA CTD PMID:22363485 NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809 		JBrowse link
G Eaf1 ELL associated factor 1 increases expression ISO Melphalan results in increased expression of EAF1 mRNA CTD PMID:22363485 NCBI chr16:6,704,727...6,719,476
Ensembl chr16:6,704,727...6,719,476 		JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Melphalan results in decreased expression of EBF1 mRNA CTD PMID:22363485 NCBI chr10:29,597,221...29,990,571
Ensembl chr10:29,601,351...29,988,702 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Melphalan results in increased expression of EDN1 protein CTD PMID:18548196 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 decreases expression ISO Melphalan results in decreased expression of EEPD1 mRNA CTD PMID:22363485 NCBI chr 8:32,233,834...32,340,148
Ensembl chr 8:32,233,070...32,340,147 		JBrowse link
G Efna2 ephrin A2 increases expression ISO Melphalan results in increased expression of EFNA2 mRNA CTD PMID:22363485 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:10,167,091...10,177,719 		JBrowse link
G Efna5 ephrin A5 decreases expression ISO Melphalan results in decreased expression of EFNA5 mRNA CTD PMID:22363485 NCBI chr 9:109,763,786...110,042,396
Ensembl chr 9:109,767,252...110,042,348 		JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Melphalan results in decreased expression of EMX2 mRNA CTD PMID:22363485 NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671 		JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 decreases expression ISO Melphalan results in decreased expression of ENOX1 mRNA CTD PMID:22363485 NCBI chr15:52,517,833...53,079,752
Ensembl chr15:59,215,018...59,488,918 		JBrowse link
G Epha5 EPH receptor A5 decreases expression ISO Melphalan results in decreased expression of EPHA5 mRNA CTD PMID:22363485 NCBI chr14:24,007,400...24,374,854
Ensembl chr14:24,008,122...24,374,848 		JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO Melphalan results in decreased expression of EXOC6 mRNA CTD PMID:22363485 NCBI chr 1:244,727,084...244,870,263
Ensembl chr 1:244,711,981...244,870,396 		JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Melphalan results in increased expression of FABP5 mRNA CTD PMID:22363485 NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127 		JBrowse link
G Fam110b family with sequence similarity 110, member B decreases expression ISO Melphalan results in decreased expression of FAM110B mRNA CTD PMID:22363485 NCBI chr 5:23,587,093...23,727,188
Ensembl chr 5:23,586,867...23,799,583 		JBrowse link
G Fam90a1a family with sequence similarity 90 member A1A decreases expression ISO Melphalan results in decreased expression of FAM90A1 mRNA CTD PMID:22363485 NCBI chr16:76,801,218...76,808,469 JBrowse link
G Fancc FA complementation group C increases response to substance ISO FANCC protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096 		JBrowse link
G Fancg FA complementation group G increases response to substance ISO FANCG protein results in increased susceptibility to Melphalan CTD PMID:16243825 NCBI chr 5:62,027,494...62,037,202
Ensembl chr 5:62,027,500...62,035,787 		JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO Melphalan results in decreased expression of FAT4 mRNA CTD PMID:22363485 NCBI chr 2:123,855,289...123,984,716
Ensembl chr 2:123,855,289...123,984,716 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 decreases expression ISO Melphalan results in decreased expression of FGD4 mRNA CTD PMID:22363485 NCBI chr11:97,904,182...98,055,190
Ensembl chr11:97,904,182...98,055,190 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 decreases expression ISO Melphalan results in decreased expression of FGD6 mRNA CTD PMID:22363485 NCBI chr 7:30,484,600...30,599,898
Ensembl chr 7:30,484,600...30,595,806 		JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Melphalan results in decreased expression of FGF5 mRNA CTD PMID:22363485 NCBI chr14:11,627,906...11,650,243
Ensembl chr14:11,627,906...11,650,243 		JBrowse link
G Fign fidgetin, microtubule severing factor decreases expression ISO Melphalan results in decreased expression of FIGN mRNA CTD PMID:22363485 NCBI chr 3:48,637,510...48,760,772
Ensembl chr 3:69,045,050...69,169,988 		JBrowse link
G Fmn2 formin 2 decreases expression ISO Melphalan results in decreased expression of FMN2 mRNA CTD PMID:22363485 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:88,986,842...89,303,789 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Melphalan results in increased expression of FOSB mRNA CTD PMID:22363485 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Foxp2 forkhead box P2 decreases expression ISO Melphalan results in decreased expression of FOXP2 mRNA CTD PMID:22363485 NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:44,099,959...44,677,696 		JBrowse link
G Frmd4a FERM domain containing 4A decreases expression ISO Melphalan results in decreased expression of FRMD4A mRNA CTD PMID:22363485 NCBI chr17:78,577,062...79,167,924
Ensembl chr17:78,579,277...79,167,663 		JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO Melphalan results in decreased expression of FRMD4B mRNA CTD PMID:22363485 NCBI chr 4:131,452,361...131,778,734
Ensembl chr 4:131,452,365...131,640,287 		JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO Melphalan results in decreased expression of FRY mRNA CTD PMID:22363485 NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603 		JBrowse link
G Fut10 fucosyltransferase 10 decreases expression ISO Melphalan results in decreased expression of POFUT3 mRNA CTD PMID:22363485 NCBI chr16:60,868,761...60,958,762
Ensembl chr16:67,581,565...67,661,753 		JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression ISO Melphalan results in decreased expression of GAB1 mRNA CTD PMID:22363485 NCBI chr19:44,035,693...44,143,617
Ensembl chr19:44,035,063...44,143,617 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 decreases expression ISO Melphalan results in decreased expression of GAREM1 mRNA CTD PMID:22363485 NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,695,082...12,860,219 		JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO Melphalan results in decreased expression of GAS1 mRNA CTD PMID:22363485 NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657 		JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 decreases expression ISO Melphalan results in decreased expression of GCNT1 mRNA CTD PMID:22363485 NCBI chr 1:224,145,104...224,182,496
Ensembl chr 1:224,141,108...224,185,741 		JBrowse link
G Glb1 galactosidase, beta 1 increases expression ISO Melphalan results in increased expression of GLB1 protein CTD PMID:33491125 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326 		JBrowse link
G Gli3 GLI family zinc finger 3 decreases expression ISO Melphalan results in decreased expression of GLI3 mRNA CTD PMID:22363485 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression ISO Melphalan results in increased expression of GRIN2C mRNA CTD PMID:22363485 NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,987,513...101,005,409 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 decreases expression ISO Melphalan results in decreased expression of GRK5 mRNA CTD PMID:22363485 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases response to substance EXP GSTA3 protein results in decreased susceptibility to Melphalan CTD PMID:8860835 PMID:10215608 PMID:10830723 NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases response to substance EXP GSTA5 protein results in decreased susceptibility to Melphalan CTD PMID:12076520 NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases response to substance ISO GSTM1 protein results in decreased susceptibility to Melphalan CTD PMID:20067466 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]; Melphalan inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:12791655 PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Melphalan results in decreased susceptibility to Melphalan]] which results in increased expression of H2AX protein modified form CTD PMID:25351371 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression ISO Melphalan results in decreased expression of HECW2 mRNA CTD PMID:22363485 NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:62,859,645...63,074,758 		JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO Melphalan results in decreased expression of HGF mRNA CTD PMID:22363485 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO Melphalan results in decreased expression of HMGA2 mRNA CTD PMID:22363485 NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:57,765,675...57,880,341 		JBrowse link
G Hoxd1 homeo box D1 increases expression ISO Melphalan results in increased expression of HOXD1 mRNA CTD PMID:22363485 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:80,073,041...80,075,180 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Melphalan results in increased expression of ICAM1 protein CTD PMID:16025434 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO Melphalan results in increased expression of IER3 mRNA CTD PMID:22363485 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Ift70b intraflagellar transport 70B decreases expression ISO Melphalan results in decreased expression of IFT70B mRNA CTD PMID:22363485 NCBI chr 3:81,263,074...81,265,645 JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO Melphalan results in decreased expression of IKBKE mRNA CTD PMID:22363485 NCBI chr13:45,264,404...45,290,737
Ensembl chr13:45,264,412...45,289,396 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Melphalan results in decreased expression of IKZF2 mRNA CTD PMID:22363485 NCBI chr 9:78,495,670...78,640,896
Ensembl chr 9:78,492,275...78,640,463 		JBrowse link
G Il12a interleukin 12A increases expression ISO Melphalan results in increased expression of IL12A mRNA CTD PMID:22363485 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il16 interleukin 16 decreases expression ISO Melphalan results in decreased expression of IL16 mRNA CTD PMID:22363485 NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		ISO Melphalan results in increased expression of and results in increased secretion of IL1B protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL1B protein]
Melphalan results in increased expression of IL1B mRNA 		CTD PMID:21129433 PMID:22363485 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions 		ISO Melphalan results in increased expression of IL23A protein
TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein] 		CTD PMID:21129433 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Melphalan results in increased expression of and results in increased secretion of IL6 protein; TCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL6 protein] CTD PMID:21129433 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il7 interleukin 7 decreases expression ISO Melphalan results in decreased expression of IL7 mRNA CTD PMID:22363485 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO Melphalan results in decreased expression of IRF2 mRNA CTD PMID:22363485 NCBI chr16:52,171,855...52,283,620
Ensembl chr16:52,164,442...52,282,627 		JBrowse link
G Jade2 jade family PHD finger 2 decreases expression ISO Melphalan results in decreased expression of JADE2 mRNA CTD PMID:22363485 NCBI chr10:36,576,187...36,625,129
Ensembl chr10:36,576,187...36,623,532 		JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO Melphalan results in decreased expression of JAK2 mRNA CTD PMID:22363485 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 decreases expression ISO Melphalan results in decreased expression of JAKMIP3 mRNA CTD PMID:22363485 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:203,241,125...203,310,713 		JBrowse link
G Kalrn kalirin, RhoGEF kinase decreases expression ISO Melphalan results in decreased expression of KALRN mRNA CTD PMID:22363485 NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329 		JBrowse link
G Kbtbd3 kelch repeat and BTB domain containing 3 decreases expression ISO Melphalan results in decreased expression of KBTBD3 mRNA CTD PMID:22363485 NCBI chr 8:9,749,229...9,780,036
Ensembl chr 8:9,749,175...9,774,555 		JBrowse link
G Kitlg KIT ligand decreases expression ISO Melphalan results in decreased expression of KITLG mRNA CTD PMID:22363485 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793 		JBrowse link
G Klf12 KLF transcription factor 12 decreases expression ISO Melphalan results in decreased expression of KLF12 mRNA CTD PMID:22363485 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:83,045,463...83,670,640 		JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Melphalan results in increased expression of KLHL42 mRNA CTD PMID:22363485 NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:181,735,244...181,757,013 		JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO Melphalan results in decreased expression of LRIG3 mRNA CTD PMID:22363485 NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:63,701,778...63,752,261 		JBrowse link
G Lurap1 leucine rich adaptor protein 1 decreases expression ISO Melphalan results in decreased expression of LURAP1 mRNA CTD PMID:22363485 NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:134,855,224...134,865,459 		JBrowse link
G Lyst lysosomal trafficking regulator decreases expression ISO Melphalan results in decreased expression of LYST mRNA CTD PMID:22363485 NCBI chr17:93,225,509...93,427,650
Ensembl chr17:93,225,540...93,427,650 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:16025434 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Melphalan results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16025434 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Melphalan results in decreased expression of MBOAT1 mRNA CTD PMID:22363485 NCBI chr17:34,540,032...34,653,705
Ensembl chr17:34,540,041...34,653,698 		JBrowse link
G Meox2 mesenchyme homeobox 2 decreases expression ISO Melphalan results in decreased expression of MEOX2 mRNA CTD PMID:22363485 NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:59,583,785...59,644,700 		JBrowse link
G Mex3a mex-3 RNA binding family member A increases expression ISO Melphalan results in increased expression of MEX3A mRNA CTD PMID:22363485 NCBI chr 2:173,990,098...173,999,567
Ensembl chr 2:176,287,900...176,297,369 		JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression ISO Melphalan results in increased expression of MEX3B mRNA CTD PMID:22363485 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:146,264,318...146,268,543 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid increases expression ISO Melphalan results in increased expression of MFSD2A mRNA CTD PMID:22363485 NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases response to substance ISO MGST2 protein results in decreased susceptibility to Melphalan CTD PMID:15779864 NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Melphalan results in decreased expression of MITF mRNA CTD PMID:22363485 NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790 		JBrowse link
G Mllt3 MLLT3, super elongation complex subunit decreases expression ISO Melphalan results in decreased expression of MLLT3 mRNA CTD PMID:22363485 NCBI chr 5:107,305,008...107,561,352
Ensembl chr 5:107,284,766...107,561,352 		JBrowse link
G Mms22l MMS22-like, DNA repair protein decreases expression ISO Melphalan results in decreased expression of MMS22L mRNA CTD PMID:22363485 NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:42,994,359...43,110,369 		JBrowse link
G Mrtfb myocardin related transcription factor B decreases expression ISO Melphalan results in decreased expression of MRTFB mRNA CTD PMID:22363485 NCBI chr10:1,623,887...1,789,658
Ensembl chr10:1,623,940...1,789,658 		JBrowse link
G Mta3 metastasis associated 1 family, member 3 decreases expression ISO Melphalan results in decreased expression of MTA3 mRNA CTD PMID:22363485 NCBI chr 6:16,619,575...16,739,732
Ensembl chr 6:16,621,998...16,739,485 		JBrowse link
G Mtcl1 microtubule crosslinking factor 1 decreases expression ISO Melphalan results in decreased expression of MTCL1 mRNA CTD PMID:22363485 NCBI chr 9:113,722,138...113,888,413
Ensembl chr 9:113,753,000...113,888,098 		JBrowse link
G Myo1b myosin Ib decreases expression ISO Melphalan results in decreased expression of MYO1B mRNA CTD PMID:22363485 NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328 		JBrowse link
G Nebl nebulette increases expression ISO Melphalan results in increased expression of NEBL mRNA CTD PMID:22363485 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:85,022,963...85,374,172 		JBrowse link
G Nfia nuclear factor I/A decreases expression ISO Melphalan results in decreased expression of NFIA mRNA CTD PMID:22363485 NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395 		JBrowse link
G Nhs NHS actin remodeling regulator decreases expression ISO Melphalan results in decreased expression of NHS mRNA CTD PMID:22363485 NCBI chr  X:32,553,300...32,892,961
Ensembl chr  X:36,438,178...36,524,708 		JBrowse link
G Nkrf NFKB repressing factor increases expression ISO Melphalan results in increased expression of NKRF mRNA CTD PMID:22363485 NCBI chr  X:116,126,341...116,144,554
Ensembl chr  X:120,992,038...121,010,251 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO Melphalan results in increased expression of NOP56 mRNA CTD PMID:22363485 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959 		JBrowse link
G Nppb natriuretic peptide B increases expression ISO Melphalan results in increased expression of NPPB protein CTD PMID:18548196 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Melphalan results in increased expression of NR4A3 mRNA CTD PMID:22363485 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285 		JBrowse link
G Nrg2 neuregulin 2 decreases expression ISO Melphalan results in decreased expression of NRG2 mRNA CTD PMID:22363485 NCBI chr18:27,890,578...28,072,538
Ensembl chr18:27,890,578...28,072,538 		JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO Melphalan results in decreased expression of NRP1 mRNA CTD PMID:22363485 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Melphalan results in decreased expression of NUAK1 mRNA CTD PMID:22363485 NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:21,217,681...21,289,354 		JBrowse link
G Osbpl10 oxysterol binding protein-like 10 decreases expression ISO Melphalan results in decreased expression of OSBPL10 mRNA CTD PMID:22363485 NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:123,539,235...123,796,822 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO Melphalan results in decreased expression of PAG1 mRNA CTD PMID:22363485 NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:93,964,594...93,977,227 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Melphalan results in decreased expression of PDLIM5 mRNA CTD PMID:22363485 NCBI chr 2:233,625,478...233,793,582
Ensembl chr 2:233,628,503...233,793,528 		JBrowse link
G Phf21a PHD finger protein 21A decreases expression ISO Melphalan results in decreased expression of PHF21A mRNA CTD PMID:22363485 NCBI chr 3:98,600,933...98,791,132
Ensembl chr 3:98,613,844...98,787,350 		JBrowse link
G Phf3 PHD finger protein 3 decreases expression ISO Melphalan results in decreased expression of PHF3 mRNA CTD PMID:22363485 NCBI chr 9:40,559,929...40,632,096
Ensembl chr 9:40,559,929...40,632,056 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Melphalan results in increased expression of PHLDA1 mRNA CTD PMID:22363485 NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases expression ISO Melphalan results in decreased expression of PHLDB2 mRNA CTD PMID:22363485 NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis
multiple interactions 		EXP Melphalan results in increased mutagenesis of PIGA
Melphalan results in increased mutagenesis of and results in decreased activity of PIGA protein 		CTD PMID:22923490 PMID:27931811 NCBI chr  X:33,672,832...33,687,747
Ensembl chr  X:33,674,923...33,687,636 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO Melphalan results in decreased expression of PIK3R1 mRNA CTD PMID:22363485 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO Melphalan results in decreased expression of PIK3R3 mRNA CTD PMID:22363485 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762 		JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression ISO Melphalan results in decreased expression of PLCL2 mRNA CTD PMID:22363485 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,529,841...3,713,712 		JBrowse link
G Plekha2 pleckstrin homology domain containing A2 decreases expression ISO Melphalan results in decreased expression of PLEKHA2 mRNA CTD PMID:22363485 NCBI chr16:66,938,684...67,000,661
Ensembl chr16:73,641,344...73,703,087 		JBrowse link
G Plekha5 pleckstrin homology domain containing A5 decreases expression ISO Melphalan results in decreased expression of PLEKHA5 mRNA CTD PMID:22363485 NCBI chr 4:175,065,011...175,234,672
Ensembl chr 4:175,065,183...175,234,672 		JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Melphalan results in increased expression of PLK3 mRNA CTD PMID:22363485 NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:135,843,725...135,848,900 		JBrowse link
G Ppif peptidylprolyl isomerase F increases expression ISO Melphalan results in increased expression of PPIF mRNA CTD PMID:22363485 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954 		JBrowse link
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H decreases expression ISO Melphalan results in decreased expression of PPM1H mRNA CTD PMID:22363485 NCBI chr 7:60,224,087...60,484,947
Ensembl chr 7:60,223,745...60,488,140 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO Melphalan results in decreased expression of PPP2R2B mRNA CTD PMID:22363485 NCBI chr18:34,904,686...35,357,299
Ensembl chr18:34,904,686...35,356,977 		JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha decreases expression ISO Melphalan results in decreased expression of PPP2R5A mRNA CTD PMID:22363485 NCBI chr13:102,931,264...102,975,661
Ensembl chr13:105,462,371...105,506,767 		JBrowse link
G Prune2 prune homolog 2 with BCH domain decreases expression ISO Melphalan results in decreased expression of PRUNE2 mRNA CTD PMID:22363485 NCBI chr 1:223,779,617...224,130,058
Ensembl chr 1:223,969,102...224,051,592 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 decreases expression ISO Melphalan results in decreased expression of PSD3 mRNA CTD PMID:22363485 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:26,340,028...26,802,535 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Melphalan results in increased expression of PTGS2 mRNA CTD PMID:22363485 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression ISO Melphalan results in decreased expression of PTPRG mRNA CTD PMID:22363485 NCBI chr15:12,871,706...13,552,186
Ensembl chr15:15,302,133...15,982,668 		JBrowse link
G Pxk PX domain containing serine/threonine kinase like decreases expression ISO Melphalan results in decreased expression of PXK mRNA CTD PMID:22363485 NCBI chr15:19,190,085...19,258,711
Ensembl chr15:19,190,085...19,258,671 		JBrowse link
G Rad54b RAD54 homolog B decreases expression ISO Melphalan results in decreased expression of RAD54B mRNA CTD PMID:22363485 NCBI chr 5:29,829,465...29,901,967
Ensembl chr 5:29,855,304...29,901,964 		JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked decreases expression ISO Melphalan results in decreased expression of RADX mRNA CTD PMID:22363485 NCBI chr  X:107,877,835...107,965,476
Ensembl chr  X:107,877,920...107,965,476 		JBrowse link
G Ralgdsl1 ral guanine nucleotide dissociation stimulator like 1 decreases expression ISO Melphalan results in decreased expression of RGL1 mRNA CTD PMID:22363485 NCBI chr13:67,184,402...67,454,019
Ensembl chr13:67,184,402...67,454,019 		JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO Melphalan results in decreased expression of RARB mRNA CTD PMID:22363485 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO Melphalan results in increased expression of RASD1 mRNA CTD PMID:22363485 NCBI chr10:45,265,975...45,275,279
Ensembl chr10:45,265,979...45,267,710 		JBrowse link
G Rasl10a RAS-like, family 10, member A increases expression ISO Melphalan results in increased expression of RASL10A mRNA CTD PMID:22363485 NCBI chr14:79,955,093...79,956,471
Ensembl chr14:84,168,227...84,170,495 		JBrowse link
G Rasl11b RAS-like family 11 member B increases expression ISO Melphalan results in increased expression of RASL11B mRNA CTD PMID:22363485 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,368,726...34,373,250 		JBrowse link
G Rbm24 RNA binding motif protein 24 increases expression ISO Melphalan results in increased expression of RBM24 mRNA CTD PMID:22363485 NCBI chr17:18,481,893...18,494,440
Ensembl chr17:18,481,900...18,494,604 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit decreases expression ISO Melphalan results in decreased expression of REV3L mRNA CTD PMID:22363485 NCBI chr20:44,686,482...44,844,668
Ensembl chr20:44,686,940...44,844,668 		JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b decreases expression ISO Melphalan results in decreased expression of RGMB mRNA CTD PMID:22363485 NCBI chr 1:65,439,748...65,465,149
Ensembl chr 1:65,441,410...65,465,098 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Melphalan results in increased expression of RGS16 mRNA CTD PMID:22363485 NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Melphalan results in increased expression of RGS2 mRNA CTD PMID:22363485 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 decreases expression ISO Melphalan results in decreased expression of RIPOR2 mRNA CTD PMID:22363485 NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,751,771...40,975,337 		JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO Melphalan results in decreased expression of RNF128 mRNA CTD PMID:22363485 NCBI chr  X:107,968,973...108,087,037
Ensembl chr  X:107,972,348...108,087,288 		JBrowse link
G Rnf144b ring finger protein 144B decreases expression ISO Melphalan results in decreased expression of RNF144B mRNA CTD PMID:22363485 NCBI chr17:17,637,564...17,786,685
Ensembl chr17:17,639,079...17,769,037 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO Melphalan results in decreased expression of ROR1 mRNA CTD PMID:22363485 NCBI chr 5:119,859,744...120,203,573
Ensembl chr 5:119,859,970...120,205,801 		JBrowse link
G Rpl27a ribosomal protein L27A increases expression ISO Melphalan results in increased expression of RPL27A mRNA CTD PMID:22363485 NCBI chr 1:172,971,957...172,977,591 JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Melphalan results in increased expression of RRAD mRNA CTD PMID:22363485 NCBI chr19:360,581...363,874
Ensembl chr19:360,973...363,871 		JBrowse link
G Rspo2 R-spondin 2 decreases expression ISO Melphalan results in decreased expression of RSPO2 mRNA CTD PMID:22363485 NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:75,987,817...76,123,654 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 decreases expression ISO Melphalan results in decreased expression of RUNX1T1 mRNA CTD PMID:22363485 NCBI chr 5:31,984,946...32,136,878
Ensembl chr 5:31,984,855...32,132,855 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 decreases expression ISO Melphalan results in decreased expression of SCN8A mRNA CTD PMID:22363485 NCBI chr 7:133,860,901...134,034,809
Ensembl chr 7:133,861,227...134,030,026 		JBrowse link
G Sema6d semaphorin 6D decreases expression ISO Melphalan results in decreased expression of SEMA6D mRNA CTD PMID:22363485 NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:132,337,343...132,394,584 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Melphalan results in increased expression of SERPINB2 mRNA CTD PMID:22363485 NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Melphalan results in increased expression of SGK1 mRNA CTD PMID:22363485 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231 		JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO Melphalan results in decreased expression of SGMS1 mRNA CTD PMID:22363485 NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:239,409,991...239,505,774 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 decreases expression ISO Melphalan results in decreased expression of SHANK2 mRNA CTD PMID:22363485 NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:208,598,772...209,018,736 		JBrowse link
G Shroom3 shroom family member 3 decreases expression ISO Melphalan results in decreased expression of SHROOM3 mRNA CTD PMID:22363485 NCBI chr14:15,099,415...15,396,832
Ensembl chr14:15,383,769...15,680,462 		JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Melphalan results in increased expression of SIK1 mRNA CTD PMID:22363485 NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO Melphalan results in decreased expression of SLC14A1 mRNA CTD PMID:22363485 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:73,840,569...73,870,489 		JBrowse link
G Slc19a2 solute carrier family 19 member 2 increases expression ISO Melphalan results in increased expression of SLC19A2 mRNA CTD PMID:22363485 NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation 		ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Melphalan results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388 		JBrowse link
G Smad3 SMAD family member 3 decreases expression ISO Melphalan results in decreased expression of SMAD3 mRNA CTD PMID:22363485 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Snord22 small nucleolar RNA, C/D box 22 increases expression ISO Melphalan results in increased expression of SNORD22 mRNA CTD PMID:22363485 NCBI chr11:22,544,203...22,544,327
Ensembl chr11:22,544,203...22,544,327 		JBrowse link
G Sntb1 syntrophin, beta 1 decreases expression ISO Melphalan results in decreased expression of SNTB1 mRNA CTD PMID:22363485 NCBI chr 7:88,950,642...89,219,017
Ensembl chr 7:88,950,642...89,219,017 		JBrowse link
G Snx29 sorting nexin 29 decreases expression ISO Melphalan results in decreased expression of SNX29 mRNA CTD PMID:22363485 NCBI chr10:4,391,866...4,805,682
Ensembl chr10:4,394,544...4,813,772 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression ISO Melphalan results in decreased expression of SOCS5 mRNA CTD PMID:22363485 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
G Spata17 spermatogenesis associated 17 decreases expression ISO Melphalan results in decreased expression of SPATA17 mRNA CTD PMID:22363485 NCBI chr13:101,137,415...101,316,221
Ensembl chr13:101,137,415...101,316,376 		JBrowse link
G Spata7 spermatogenesis associated 7 decreases expression ISO Melphalan results in decreased expression of SPATA7 mRNA CTD PMID:22363485 NCBI chr 6:123,609,519...123,655,001
Ensembl chr 6:123,609,535...123,655,001 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 decreases expression ISO Melphalan results in decreased expression of SPRED1 mRNA CTD PMID:22363485 NCBI chr 3:124,437,230...124,504,358
Ensembl chr 3:124,437,230...124,504,358 		JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 increases expression ISO Melphalan results in increased expression of SPTY2D1 mRNA CTD PMID:22363485 NCBI chr 1:106,667,750...106,685,871
Ensembl chr 1:106,667,750...106,685,871 		JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 decreases expression ISO Melphalan results in decreased expression of SRGAP2 mRNA CTD PMID:22363485 NCBI chr13:45,298,192...45,519,330
Ensembl chr13:45,298,192...45,519,330 		JBrowse link
G Stac SH3 and cysteine rich domain decreases expression ISO Melphalan results in decreased expression of STAC mRNA CTD PMID:22363485 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:120,409,165...120,531,320 		JBrowse link
G Stambpl1 STAM binding protein-like 1 decreases expression ISO Melphalan results in decreased expression of STAMBPL1 mRNA CTD PMID:22363485 NCBI chr 1:241,095,695...241,158,225
Ensembl chr 1:241,113,239...241,158,225 		JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO Melphalan results in decreased expression of TACC2 mRNA CTD PMID:22363485 NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152 		JBrowse link
G Tbc1d12 TBC1 domain family, member 12 decreases expression ISO Melphalan results in decreased expression of TBC1D12 mRNA CTD PMID:22363485 NCBI chr 1:246,015,985...246,098,241
Ensembl chr 1:246,015,994...246,098,241 		JBrowse link
G Tbl1xr1 TBL1X/Y related 1 decreases expression ISO Melphalan results in decreased expression of TBL1XR1 mRNA CTD PMID:22363485 NCBI chr 2:106,718,811...106,857,989
Ensembl chr 2:106,730,665...106,857,989 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 decreases expression ISO Melphalan results in decreased expression of TET1 mRNA CTD PMID:22363485 NCBI chr20:25,766,806...25,839,598
Ensembl chr20:25,760,057...25,832,730 		JBrowse link
G Tex30 testis expressed 30 increases expression ISO Melphalan results in increased expression of TEX30 mRNA CTD PMID:22363485 NCBI chr 9:53,735,512...53,744,672
Ensembl chr 9:53,735,512...53,741,042 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Melphalan results in increased expression of TFPI2 mRNA CTD PMID:22363485 NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa] CTD PMID:9509296 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 decreases expression ISO Melphalan results in decreased expression of THSD4 mRNA CTD PMID:22363485 NCBI chr 8:60,384,636...60,984,419
Ensembl chr 8:69,284,646...69,917,342 		JBrowse link
G Tigd2 tigger transposable element derived 2 decreases expression ISO Melphalan results in decreased expression of TIGD2 mRNA CTD PMID:22363485 NCBI chr 4:89,744,516...89,747,608
Ensembl chr 4:89,744,510...89,747,940 		JBrowse link
G Tlnrd1 talin rod domain containing 1 increases expression ISO Melphalan results in increased expression of TLNRD1 mRNA CTD PMID:22363485 NCBI chr 1:137,864,340...137,866,359
Ensembl chr 1:147,178,456...147,283,303 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Melphalan results in decreased expression of TLR4 mRNA CTD PMID:22363485 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tmem131l transmembrane 131 like decreases expression ISO Melphalan results in decreased expression of TMEM131L mRNA CTD PMID:22363485 NCBI chr 2:171,555,673...171,689,774
Ensembl chr 2:171,555,673...171,689,733 		JBrowse link
G Tmem200a transmembrane protein 200A decreases expression ISO Melphalan results in decreased expression of TMEM200A mRNA CTD PMID:22363485 NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:21,141,432...21,426,175 		JBrowse link
G Tmem26 transmembrane protein 26 decreases expression ISO Melphalan results in decreased expression of TMEM26 mRNA CTD PMID:22363485 NCBI chr20:19,820,768...19,872,561
Ensembl chr20:19,821,991...19,871,041 		JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Melphalan results in increased expression of TMEM88 mRNA CTD PMID:22363485 NCBI chr10:54,617,554...54,619,309
Ensembl chr10:54,617,630...54,619,438 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Melphalan results in increased expression of TNF mRNA CTD PMID:16025434 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 decreases expression ISO Melphalan results in decreased expression of TNFRSF19 mRNA CTD PMID:22363485 NCBI chr15:39,268,305...39,334,566
Ensembl chr15:39,268,305...39,356,438 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Melphalan results in increased expression of TNNI3 protein CTD PMID:18548196 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B decreases expression ISO Melphalan results in decreased expression of TNRC6B mRNA CTD PMID:22363485 NCBI chr 7:114,132,574...114,350,010
Ensembl chr 7:114,132,573...114,342,973 		JBrowse link
G Tox thymocyte selection-associated high mobility group box decreases expression ISO Melphalan results in decreased expression of TOX mRNA CTD PMID:22363485 NCBI chr 5:24,672,487...24,968,754
Ensembl chr 5:24,672,487...24,968,754 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Melphalan affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Melphalan results in decreased expression of TP63 mRNA CTD PMID:22363485 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:88,343,651...88,554,177 		JBrowse link
G Trerf1 transcriptional regulating factor 1 decreases expression ISO Melphalan results in decreased expression of TRERF1 mRNA CTD PMID:22363485 NCBI chr 9:21,131,772...21,355,830
Ensembl chr 9:21,131,777...21,176,016 		JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Melphalan results in increased expression of TRIB1 mRNA CTD PMID:22363485 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:93,095,973...93,117,480 		JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit increases expression ISO Melphalan results in increased expression of TRMT10C mRNA CTD PMID:22363485 NCBI chr11:58,053,455...58,058,533
Ensembl chr11:58,033,201...58,059,062 		JBrowse link
G Tubg1 tubulin, gamma 1 increases expression ISO Melphalan results in increased expression of TUBG1 protein CTD PMID:22025197 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,552,499...86,559,730 		JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Melphalan results in increased expression of TUFT1 mRNA CTD PMID:22363485 NCBI chr 2:184,949,437...184,995,321
Ensembl chr 2:184,949,437...184,995,383 		JBrowse link
G Twnk twinkle mtDNA helicase increases expression ISO Melphalan results in increased expression of TWNK mRNA CTD PMID:22363485 NCBI chr 1:253,817,074...253,823,958
Ensembl chr 1:253,817,564...253,824,162 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP Melphalan results in decreased activity of TXNRD1 protein CTD PMID:16085187 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Ubap1l ubiquitin associated protein 1-like increases expression ISO Melphalan results in increased expression of UBAP1L mRNA CTD PMID:22363485 NCBI chr 8:74,772,794...74,792,753
Ensembl chr 8:74,781,395...74,792,716 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Melphalan results in increased expression of USP36 mRNA CTD PMID:22363485 NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,995,970...104,023,450 		JBrowse link
G Usp53 ubiquitin specific peptidase 53 decreases expression ISO Melphalan results in decreased expression of USP53 mRNA CTD PMID:22363485 NCBI chr 2:211,059,512...211,120,942
Ensembl chr 2:213,744,106...213,790,544 		JBrowse link
G Utp25 UTP25 small subunit processome component increases expression ISO Melphalan results in increased expression of UTP25 mRNA CTD PMID:22363485 NCBI chr13:104,630,390...104,651,681
Ensembl chr13:107,149,183...107,180,361 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [arsenic trioxide results in increased expression of VDAC1 protein] which results in increased susceptibility to Melphalan CTD PMID:22285227 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Yod1 YOD1 deubiquitinase increases expression ISO Melphalan results in increased expression of YOD1 mRNA CTD PMID:22363485 NCBI chr13:44,727,319...44,733,933 JBrowse link
G Ypel2 yippee-like 2 decreases expression ISO Melphalan results in decreased expression of YPEL2 mRNA CTD PMID:22363485 NCBI chr10:71,746,308...71,803,843
Ensembl chr10:72,243,591...72,301,124 		JBrowse link
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing increases expression ISO Melphalan results in increased expression of YRDC mRNA CTD PMID:22363485 NCBI chr 5:142,394,833...142,399,798
Ensembl chr 5:142,394,938...142,399,795 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression ISO Melphalan results in decreased expression of ZBTB20 mRNA CTD PMID:22363485 NCBI chr11:70,558,010...71,297,039
Ensembl chr11:70,580,930...70,736,237 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Melphalan results in increased expression of ZC3H12A mRNA CTD PMID:22363485 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985 		JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO Melphalan results in decreased expression of ZFHX4 mRNA CTD PMID:22363485 NCBI chr 2:98,131,996...98,321,070
Ensembl chr 2:98,131,996...98,315,469 		JBrowse link
G Zfp277 zinc finger protein 277 decreases expression ISO Melphalan results in decreased expression of ZNF277 mRNA CTD PMID:22363485 NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:63,110,609...63,239,831 		JBrowse link
G Zfp438 zinc finger protein 438 decreases expression ISO Melphalan results in decreased expression of ZNF438 mRNA CTD PMID:22363485 NCBI chr17:57,121,637...57,242,892
Ensembl chr17:57,121,302...57,245,607 		JBrowse link
G Zfp521 zinc finger protein 521 decreases expression ISO Melphalan results in decreased expression of ZNF521 mRNA CTD PMID:22363485 NCBI chr18:4,775,952...5,068,592
Ensembl chr18:5,056,236...5,343,054 		JBrowse link
G Zfp618 zinc finger protein 618 decreases expression ISO Melphalan results in decreased expression of ZNF618 mRNA CTD PMID:22363485 NCBI chr 5:76,398,514...76,564,837
Ensembl chr 5:81,413,814...81,575,549 		JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression ISO Melphalan results in decreased expression of ZSWIM5 mRNA CTD PMID:22363485 NCBI chr 5:130,346,733...130,463,791
Ensembl chr 5:135,582,724...135,700,390 		JBrowse link
phosphoramide mustard term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression EXP phosphoramide mustard results in decreased expression of ABCB1 protein CTD PMID:27888070 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Atm ATM serine/threonine kinase affects expression
increases expression 		EXP phosphoramide mustard affects the expression of ATM mRNA
phosphoramide mustard results in increased expression of ATM mRNA; phosphoramide mustard results in increased expression of ATM protein 		CTD PMID:25497287 PMID:26708502 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G B2m beta-2 microglobulin decreases expression EXP phosphoramide mustard results in decreased expression of B2M mRNA CTD PMID:27888070 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP phosphoramide mustard results in increased expression of BAX mRNA CTD PMID:26708502 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression EXP phosphoramide mustard results in increased expression of BBC3 mRNA CTD PMID:26708502 PMID:27888070 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP phosphoramide mustard results in decreased expression of BCL2 protein CTD PMID:26708502 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Becn1 beclin 1 increases expression EXP phosphoramide mustard results in increased expression of BECN1 mRNA; phosphoramide mustard results in increased expression of BECN1 protein CTD PMID:27888070 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Brca1 BRCA1, DNA repair associated affects expression
increases expression 		EXP phosphoramide mustard affects the expression of BRCA1 mRNA
phosphoramide mustard results in increased expression of BRCA1 mRNA; phosphoramide mustard results in increased expression of BRCA1 protein 		CTD PMID:25497287 PMID:26708502 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763 		JBrowse link
G Casp1 caspase 1 decreases expression EXP phosphoramide mustard results in decreased expression of CASP1 mRNA CTD PMID:27888070 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 increases expression EXP phosphoramide mustard results in increased expression of CASP3 protein CTD PMID:26708502 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP phosphoramide mustard results in increased expression of CDKN1A mRNA CTD PMID:26708502 PMID:27888070 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cftr CF transmembrane conductance regulator increases expression EXP phosphoramide mustard results in increased expression of CFTR mRNA CTD PMID:27888070 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Cycs cytochrome c, somatic increases expression EXP phosphoramide mustard results in increased expression of CYCS mRNA CTD PMID:26708502 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression EXP phosphoramide mustard results in increased expression of E2F1 mRNA CTD PMID:26708502 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563 		JBrowse link
G E2f7 E2F transcription factor 7 increases expression EXP phosphoramide mustard results in increased expression of E2F7 protein CTD PMID:26708502 NCBI chr 7:48,036,881...48,079,055
Ensembl chr 7:48,037,749...48,079,055 		JBrowse link
G Edn1 endothelin 1 increases expression EXP phosphoramide mustard results in increased expression of EDN1 mRNA CTD PMID:27888070 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP phosphoramide mustard results in increased expression of EPHX1 mRNA; phosphoramide mustard results in increased expression of EPHX1 protein CTD PMID:25070981 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981 		JBrowse link
G Exo1 exonuclease 1 increases expression EXP phosphoramide mustard results in increased expression of EXO1 mRNA CTD PMID:26708502 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861 		JBrowse link
G Fancc FA complementation group C increases expression EXP phosphoramide mustard results in increased expression of FANCC mRNA CTD PMID:26708502 NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP phosphoramide mustard results in increased expression of GADD45G mRNA CTD PMID:26708502 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP phosphoramide mustard results in increased expression of GSTP1 mRNA; phosphoramide mustard results in increased expression of GSTP1 protein CTD PMID:25070981 PMID:27888070 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression 		EXP
ISO 		phosphoramide mustard results in increased phosphorylation of and results in increased expression of H2AX protein
phosphoramide mustard results in increased expression of H2AX protein 		CTD PMID:21439308 PMID:25497287 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Il1b interleukin 1 beta decreases expression EXP phosphoramide mustard results in decreased expression of IL1B mRNA CTD PMID:27888070 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression EXP phosphoramide mustard results in increased expression of LAMP1 protein CTD PMID:27888070 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP phosphoramide mustard results in increased expression of MDM2 mRNA CTD PMID:26708502 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP phosphoramide mustard results in increased expression of MGMT mRNA CTD PMID:26708502 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP phosphoramide mustard results in increased expression of NQO1 mRNA CTD PMID:27888070 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 affects expression
increases expression 		EXP phosphoramide mustard affects the expression of PARP1 mRNA
phosphoramide mustard results in increased expression of PARP1 mRNA; phosphoramide mustard results in increased expression of PARP1 protein 		CTD PMID:25497287 PMID:26708502 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit increases expression EXP phosphoramide mustard results in increased expression of POLD3 mRNA CTD PMID:26708502 NCBI chr 1:163,830,217...163,870,015
Ensembl chr 1:163,830,437...163,869,202 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit affects expression
increases expression 		EXP phosphoramide mustard affects the expression of PRKDC mRNA; phosphoramide mustard affects the expression of PRKDC protein
phosphoramide mustard results in increased expression of PRKDC mRNA 		CTD PMID:25497287 PMID:26708502 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108 		JBrowse link
G Rad21 RAD21 cohesin complex component increases expression EXP phosphoramide mustard results in increased expression of RAD21 mRNA CTD PMID:26708502 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657 		JBrowse link
G Rad51 RAD51 recombinase affects expression
increases expression
decreases expression 		EXP phosphoramide mustard affects the expression of RAD51 mRNA; phosphoramide mustard affects the expression of RAD51 protein
phosphoramide mustard results in increased expression of RAD51 mRNA
phosphoramide mustard results in decreased expression of RAD51 protein 		CTD PMID:25497287 PMID:26708502 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Rpa1 replication protein A1 increases expression EXP phosphoramide mustard results in increased expression of RPA1 mRNA CTD PMID:26708502 NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279 		JBrowse link
G Terf1 telomeric repeat binding factor 1 increases expression EXP phosphoramide mustard results in increased expression of TERF1 mRNA CTD PMID:26708502 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression EXP phosphoramide mustard results in increased expression of TLR4 mRNA CTD PMID:27888070 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression EXP phosphoramide mustard results in increased expression of TNFRSF1A mRNA CTD PMID:27888070 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 increases expression EXP phosphoramide mustard results in increased expression of TOPBP1 mRNA CTD PMID:26708502 NCBI chr 8:112,766,791...112,815,203
Ensembl chr 8:112,766,508...112,810,540 		JBrowse link
G Tp73 tumor protein p73 increases expression EXP phosphoramide mustard results in increased expression of TP73 mRNA; phosphoramide mustard results in increased expression of TP73 protein CTD PMID:26708502 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP phosphoramide mustard results in increased expression of TXNRD1 mRNA CTD PMID:27888070 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Ung uracil-DNA glycosylase increases expression EXP phosphoramide mustard results in increased expression of UNG mRNA CTD PMID:26708502 NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 affects expression EXP phosphoramide mustard affects the expression of VDAC1 mRNA CTD PMID:26708502 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 increases expression EXP phosphoramide mustard results in increased expression of XRCC2 mRNA CTD PMID:26708502 NCBI chr 4:10,157,130...10,237,089
Ensembl chr 4:10,157,800...10,176,407 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 affects expression
increases expression 		EXP phosphoramide mustard affects the expression of XRCC6 mRNA; phosphoramide mustard affects the expression of XRCC6 protein
phosphoramide mustard results in increased expression of XRCC6 mRNA 		CTD PMID:25497287 PMID:26708502 NCBI chr 7:115,423,026...115,443,884
Ensembl chr 7:115,422,662...115,443,884 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        aetiopathogenetic role 19855
          genotoxin 17988
            mutagen 17881
              alkylating agent 14513
                nitrogen mustard 1420
                  2-(\{4-[bis(2-chloroethyl)amino]-2-methylphenyl\}diazenyl)benzoic acid 0
                  3,4-Dichloro-5-hydroxy-2H-pyrrol-2-one 0
                  3,4-dibromopyrrole-2,5-dione 0
                  4-Ketocyclophosphamide 0
                  4-hydroperoxycyclophosphamide 74
                  4-hydroxycyclophosphamide 10
                  5-[bis(2-chloroethyl)amino]uracil 0
                  Alcophosphamide 0
                  Aldophosphamide 2
                  Carboxyphosphamide 0
                  N-[[4-[bis(2-chloroethyl)amino]-2-methylphenyl]methylideneamino]-2-furancarboxamide 0
                  Nitrogen mustard N-oxide 0
                  Nitrogen mustard N-oxide hydrochloride 0
                  bis(2-chloroethyl)amine 0
                  chlorambucil 52
                  cyclophosphamide + 815
                  ifosfamides + 248
                  mechlorethamine + 175
                  melphalan 275
                  perfosfamide 0
                  phosphoramide mustard 43
                  quinacrine mustard + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      p-block molecular entity 20781
                        carbon group molecular entity 20715
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organonitrogen compound 19403
                                nitrogen mustard 1420
                                  2-(\{4-[bis(2-chloroethyl)amino]-2-methylphenyl\}diazenyl)benzoic acid 0
                                  3,4-Dichloro-5-hydroxy-2H-pyrrol-2-one 0
                                  3,4-dibromopyrrole-2,5-dione 0
                                  4-Ketocyclophosphamide 0
                                  4-hydroperoxycyclophosphamide 74
                                  4-hydroxycyclophosphamide 10
                                  5-[bis(2-chloroethyl)amino]uracil 0
                                  Alcophosphamide 0
                                  Aldophosphamide 2
                                  Carboxyphosphamide 0
                                  N-[[4-[bis(2-chloroethyl)amino]-2-methylphenyl]methylideneamino]-2-furancarboxamide 0
                                  Nitrogen mustard N-oxide 0
                                  Nitrogen mustard N-oxide hydrochloride 0
                                  bis(2-chloroethyl)amine 0
                                  chlorambucil 52
                                  cyclophosphamide + 815
                                  ifosfamides + 248
                                  mechlorethamine + 175
                                  melphalan 275
                                  perfosfamide 0
                                  phosphoramide mustard 43
                                  quinacrine mustard + 0
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