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ONTOLOGY REPORT - ANNOTATIONS


Term:clomiphene
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Accession:CHEBI:3752 term browser browse the term
Definition:A tertiary amine that has formula C26H28ClNO.
Synonyms:related_synonym: 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine;   2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamine;   2-(p-(beta-chloro-alpha-phenylstyryl)phenoxy)triethylamine;   Formula=C26H28ClNO;   InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3;   InChIKey=GKIRPKYJQBWNGO-UHFFFAOYSA-N;   SMILES=CCN(CC)CCOc1ccc(cc1)C(c1ccccc1)=C(Cl)c1ccccc1;   clomifene;   clomifeno;   clomifenum
 xref: Beilstein:2302126 "Beilstein";   CAS:911-45-5 "ChemIDplus";   CAS:911-45-5 "KEGG COMPOUND";   CAS:911-45-5 "NIST Chemistry WebBook";   DrugBank:DB00882;   Drug_Central:700 "DrugCentral";   KEGG:C06917;   KEGG:D07726;   LINCS:LSM-2072
 xref_mesh: MESH:D002996
 xref: Patent:US2914563


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clomiphene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd2 abhydrolase domain containing 2 JBrowse link 1 140,998,240 141,087,405 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Ca12 carbonic anhydrase 12 JBrowse link 8 72,405,770 72,461,425 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccng2 cyclin G2 JBrowse link 14 16,267,572 16,276,068 RGD:6480464
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:6480464
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:6480464
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:6480464
G Egr3 early growth response 3 JBrowse link 15 51,756,683 51,762,080 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:6480464
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:6480464
G Id3 inhibitor of DNA binding 3, HLH protein JBrowse link 5 154,489,603 154,491,172 RGD:6480464
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6480464
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:6480464
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:6480464
G Mybl1 MYB proto-oncogene like 1 JBrowse link 5 9,279,756 9,315,112 RGD:6480464
G Nmrk1 nicotinamide riboside kinase 1 JBrowse link 1 234,721,992 234,749,452 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Olfm1 olfactomedin 1 JBrowse link 3 6,761,031 6,798,739 RGD:6480464
G Pdzk1 PDZ domain containing 1 JBrowse link 2 198,965,685 198,999,323 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 5 135,069,972 135,145,633 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Prss23 serine protease 23 JBrowse link 1 153,732,528 153,742,111 RGD:6480464
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:6480464
G Rbbp8 RB binding protein 8, endonuclease JBrowse link 18 3,134,630 3,227,702 RGD:6480464
G Rcl1 RNA terminal phosphate cyclase-like 1 JBrowse link 1 247,228,012 247,272,369 RGD:6480464
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:6480464
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:6480464
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 JBrowse link 5 9,046,889 9,094,740 RGD:6480464
G Shbg sex hormone binding globulin JBrowse link 10 56,219,861 56,237,354 RGD:6480464
G Siah2 siah E3 ubiquitin protein ligase 2 JBrowse link 2 148,874,151 148,891,900 RGD:6480464
G Smox spermine oxidase JBrowse link 3 124,068,796 124,103,726 RGD:6480464
G Ssbp2 single-stranded DNA binding protein 2 JBrowse link 2 20,416,795 20,707,838 RGD:6480464
G Svil supervillin JBrowse link 17 55,230,298 55,425,967 RGD:6480464
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:6480464
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:6480464
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            estrogen receptor modulator 3413
              clomiphene 47
                clomiphene citrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          tertiary amine 599
                                            clomiphene 47
                                              clomiphene citrate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.