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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkenyl phosphate
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Accession:CHEBI:37494 term browser browse the term
Synonyms:related_synonym: alkenyl phosphates



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dichlorvos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions
decreases expression
decreases activity
decreases response to substance
increases acylation
increases phosphorylation
EXP
ISO
[Carbaryl co-treated with Dichlorvos] results in decreased activity of ACHE protein; [crotoxyphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Dichlorvos results in increased phosphorylation of ACHE protein] inhibits the reaction [thioflavin T binds to ACHE protein]; [malaoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Mevinphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Paraoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Parathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Phosphamidon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Physostigmine co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Trichlorfon co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
Dichlorvos results in decreased expression of ACHE protein
1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [Dichlorvos co-treated with Monocrotophos] results in increased activity of ACHE protein; [Monocrotophos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [sodium arsenite co-treated with Dichlorvos co-treated with Monocrotophos] results in decreased activity of ACHE protein; [sodium arsenite co-treated with Dichlorvos] results in decreased activity of ACHE protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
ACHE protein results in decreased susceptibility to Dichlorvos
Dichlorvos results in increased acylation of ACHE protein
Dichlorvos metabolite results in decreased activity of ACHE protein; Dichlorvos results in decreased activity of ACHE protein
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Dichlorvos binds to and results in decreased activity of ACHE protein; Dichlorvos promotes the reaction [malaoxon results in decreased activity of ACHE protein]; Gallamine Triethiodide affects the reaction [Dichlorvos results in increased acylation of ACHE protein]; Gallamine Triethiodide promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Propidium promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tubocurarine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]
CTD PMID:119426 PMID:235931 PMID:473212 PMID:475593 PMID:597376 More... NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects localization
multiple interactions
ISO Dichlorvos affects the localization of AIFM1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos affects the localization of AIFM1 protein]
CTD PMID:24231740 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 increases expression ISO Dichlorvos results in increased expression of AKR7A3 mRNA CTD PMID:21813463 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770
JBrowse link
G ALB albumin affects binding EXP Dichlorvos binds to ALB protein CTD PMID:15525694 PMID:17188226 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases expression ISO Dichlorvos results in increased expression of ALDH1A1 mRNA CTD PMID:21813463 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ANXA2 annexin A2 increases expression ISO Dichlorvos results in increased expression of ANXA2 mRNA CTD PMID:21813463 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G APEH acylaminoacyl-peptide hydrolase decreases activity EXP
ISO
Dichlorvos results in decreased activity of APEH protein CTD PMID:15888665 PMID:19379766 NCBI chr 3:49,673,117...49,683,971
Ensembl chr 3:49,674,014...49,683,971
JBrowse link
G APP amyloid beta precursor protein increases secretion EXP
ISO
Dichlorvos results in increased secretion of APP protein alternative form
Dichlorvos results in increased secretion of APP protein modified form
CTD PMID:7605915 PMID:8624119 PMID:11526466 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G AR androgen receptor multiple interactions EXP Dichlorvos promotes the reaction [Metribolone results in increased activity of AR protein] CTD PMID:17219378 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ATM ATM serine/threonine kinase multiple interactions
increases expression
ISO TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ATM mRNA]
Dichlorvos results in increased expression of ATM mRNA; Dichlorvos results in increased expression of ATM protein
CTD PMID:24369695 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression ISO Dichlorvos results in increased expression of BAX protein CTD PMID:22817663 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCHE butyrylcholinesterase multiple interactions
decreases expression
decreases activity
EXP
ISO
[Dichlorvos results in decreased activity of BCHE protein] which results in increased susceptibility to Succinylcholine; Dichlorvos binds to and results in decreased activity of BCHE protein; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]
Dichlorvos results in decreased expression of BCHE protein
diacetylmonoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein]
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of BCHE protein]; Dichlorvos binds to and results in decreased activity of BCHE protein
CTD PMID:235931 PMID:423703 PMID:1276991 PMID:4631366 PMID:7150809 More... NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression ISO Dichlorvos results in increased expression of BTG2 mRNA CTD PMID:21813463 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G CASP1 caspase 1 increases expression ISO Dichlorvos results in increased expression of CASP1 mRNA CTD PMID:23053939 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 increases activity
increases cleavage
increases expression
decreases expression
multiple interactions
EXP
ISO
Dichlorvos results in increased activity of CASP3 protein
Dichlorvos results in increased cleavage of CASP3 protein
Dichlorvos results in increased expression of CASP3 mRNA
Dichlorvos results in decreased expression of CASP3 mRNA
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Dichlorvos results in increased cleavage of and results in increased activity of CASP3 protein; mitoquinone inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased cleavage of CASP3 protein]
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]
CTD PMID:16973328 PMID:17681413 PMID:17850875 PMID:19815060 PMID:21784090 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity
ISO [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein] CTD PMID:16973328 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
increases activity
decreases activity
ISO [Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of CAT protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of CAT protein; [Phorate co-treated with acephate co-treated with Dichlorvos co-treated with Dimethoate] results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; coenzyme Q10 inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
Dichlorvos results in increased activity of CAT protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
CTD PMID:1587340 PMID:20302853 PMID:22034174 PMID:22224058 PMID:22751200 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CDC25A cell division cycle 25A multiple interactions
increases expression
ISO TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A protein]
Dichlorvos results in increased expression of CDC25A mRNA; Dichlorvos results in increased expression of CDC25A protein
CTD PMID:24369695 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions
ISO Dichlorvos results in increased expression of CDKN1A mRNA; Dichlorvos results in increased expression of CDKN1A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A protein]
CTD PMID:21813463 PMID:24369695 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CES2 carboxylesterase 2 increases expression ISO Dichlorvos results in increased expression of CES2 mRNA CTD PMID:21813463 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096
JBrowse link
G CHAT choline O-acetyltransferase increases activity ISO Dichlorvos results in increased activity of CHAT protein CTD PMID:17722737 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
JBrowse link
G CHEK2 checkpoint kinase 2 multiple interactions
increases expression
ISO TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 protein]
Dichlorvos results in increased expression of CHEK2 mRNA; Dichlorvos results in increased expression of CHEK2 protein
CTD PMID:24369695 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 decreases expression ISO Dichlorvos results in decreased expression of CHRM1 protein CTD PMID:19100812 NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 decreases expression ISO Dichlorvos results in decreased expression of CHRM2 protein CTD PMID:19100812 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 decreases expression ISO Dichlorvos results in decreased expression of CHRM3 protein CTD PMID:19100812 NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions
decreases activity
ISO Dichlorvos inhibits the reaction [CP 55244 binds to CNR1 protein]
Dichlorvos results in decreased activity of CNR1 protein
CTD PMID:12243867 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CREB1 cAMP responsive element binding protein 1 decreases phosphorylation ISO Dichlorvos results in decreased phosphorylation of CREB1 protein CTD PMID:19100812 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CYBB cytochrome b-245 beta chain increases expression ISO Dichlorvos results in increased expression of CYBB mRNA; Dichlorvos results in increased expression of CYBB protein CTD PMID:21964614 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461
JBrowse link
G CYCS cytochrome c, somatic affects localization
multiple interactions
ISO Dichlorvos affects the localization of CYCS protein
mitoquinone inhibits the reaction [Dichlorvos affects the localization of CYCS protein]
CTD PMID:17850875 PMID:21784090 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G DBH dopamine beta-hydroxylase increases activity
multiple interactions
ISO Dichlorvos results in increased activity of DBH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of DBH protein]
CTD PMID:12186780 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DLG2 discs large MAGUK scaffold protein 2 affects response to substance EXP DLG2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:25622337 NCBI chr11:83,455,012...85,628,373
Ensembl chr11:83,455,012...85,627,922
JBrowse link
G DRD2 dopamine receptor D2 decreases activity
multiple interactions
ISO Dichlorvos results in decreased activity of DRD2 protein
Nimodipine inhibits the reaction [Dichlorvos results in decreased activity of DRD2 protein]
CTD PMID:12186780 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G ESR1 estrogen receptor 1 decreases activity EXP Dichlorvos results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G FAS Fas cell surface death receptor decreases expression ISO Dichlorvos results in decreased expression of FAS protein CTD PMID:15369847 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASLG Fas ligand decreases expression ISO Dichlorvos results in decreased expression of FASL protein CTD PMID:15369847 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta decreases expression ISO Dichlorvos results in decreased expression of GABRD mRNA CTD PMID:19146868 NCBI chr 1:2,019,345...2,030,758
Ensembl chr 1:2,019,329...2,030,758
JBrowse link
G GCK glucokinase decreases activity
increases expression
ISO Dichlorvos results in decreased activity of GCK protein
Dichlorvos results in increased expression of GCK mRNA
CTD PMID:16153661 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
JBrowse link
G GNLY granulysin decreases expression EXP Dichlorvos results in decreased expression of GNLY mRNA; Dichlorvos results in decreased expression of GNLY protein CTD PMID:16002202 NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852
JBrowse link
G GSR glutathione-disulfide reductase decreases expression
increases activity
decreases activity
multiple interactions
ISO Dichlorvos results in decreased expression of GSR protein
Dichlorvos results in increased activity of GSR protein
Dichlorvos results in decreased activity of GSR protein
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of GSR protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of GSR protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of GSR protein]; Plant Extracts inhibits the reaction [Dichlorvos results in decreased activity of GSR protein]; sodium arsenite inhibits the reaction [Dichlorvos results in increased activity of GSR protein]
CTD PMID:18539328 PMID:20302853 PMID:22224058 PMID:22751200 PMID:25895260 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GYS2 glycogen synthase 2 increases activity ISO Dichlorvos results in increased activity of GYS2 protein CTD PMID:222008 NCBI chr12:21,532,577...21,604,847
Ensembl chr12:21,536,107...21,604,847
JBrowse link
G GZMA granzyme A decreases expression EXP Dichlorvos results in decreased expression of GZMA mRNA; Dichlorvos results in decreased expression of GZMA protein CTD PMID:16002202 NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
JBrowse link
G GZMB granzyme B decreases expression EXP Dichlorvos results in decreased expression of GZMB protein CTD PMID:18063463 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
JBrowse link
G GZMK granzyme K decreases expression EXP Dichlorvos results in decreased expression of GZMK protein CTD PMID:18063463 NCBI chr 5:55,024,256...55,034,570
Ensembl chr 5:55,024,256...55,034,570
JBrowse link
G HDC histidine decarboxylase increases activity ISO Dichlorvos results in increased activity of HDC protein CTD PMID:119426 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G HK1 hexokinase 1 decreases activity ISO Dichlorvos results in decreased activity of HK1 protein CTD PMID:10544956 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884
JBrowse link
G HMOX1 heme oxygenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of HMOX1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]
CTD PMID:26814074 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IFNG interferon gamma decreases expression ISO Dichlorvos results in decreased expression of IFNG protein CTD PMID:19145326 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL1B interleukin 1 beta increases expression
increases secretion
ISO Dichlorvos results in increased expression of IL1B mRNA; Dichlorvos results in increased expression of IL1B protein
Dichlorvos results in increased secretion of IL1B protein
CTD PMID:21964614 PMID:22817663 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 decreases response to substance ISO Dichlorvos results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL6 interleukin 6 increases expression ISO Dichlorvos results in increased expression of IL6 mRNA; Dichlorvos results in increased expression of IL6 protein CTD PMID:21964614 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGAM integrin subunit alpha M increases expression
multiple interactions
ISO Dichlorvos results in increased expression of ITGAM mRNA; Dichlorvos results in increased expression of ITGAM protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ITGAM protein]
CTD PMID:21964614 PMID:22817663 PMID:24369695 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G LCAT lecithin-cholesterol acyltransferase decreases activity
multiple interactions
EXP Dichlorvos results in decreased activity of LCAT protein
Dichlorvos inhibits the reaction [[LCAT protein results in increased metabolism of Lecithins] which results in increased chemical synthesis of Cholesterol Esters]
CTD PMID:4847537 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LPL lipoprotein lipase decreases activity ISO Dichlorvos results in decreased activity of LPL protein CTD PMID:3196159 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G MAOA monoamine oxidase A decreases activity ISO Dichlorvos results in decreased activity of MAOA protein CTD PMID:12018584 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MAOB monoamine oxidase B decreases activity ISO Dichlorvos results in decreased activity of MAOB protein CTD PMID:12018584 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G MAP2 microtubule associated protein 2 multiple interactions
increases phosphorylation
ISO Nimodipine inhibits the reaction [Dichlorvos results in increased phosphorylation of MAP2 protein] CTD PMID:11282359 PMID:16635102 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,118
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase increases expression ISO Dichlorvos results in increased expression of MGMT mRNA CTD PMID:21813463 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G NCEH1 neutral cholesterol ester hydrolase 1 affects expression
decreases activity
ISO Dichlorvos affects the expression of NCEH1 protein modified form
Dichlorvos results in decreased activity of NCEH1 protein
CTD PMID:6245657 PMID:16978018 NCBI chr 3:172,630,249...172,711,067
Ensembl chr 3:172,630,249...172,711,218
JBrowse link
G NEFH neurofilament heavy chain affects expression ISO Dichlorvos affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
JBrowse link
G NEFL neurofilament light chain decreases expression ISO Dichlorvos results in decreased expression of NEFL mRNA CTD PMID:19146868 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases activity
decreases expression
multiple interactions
EXP
ISO
Dichlorvos results in increased activity of NFE2L2 protein
Dichlorvos results in decreased expression of NFE2L2 mRNA; Dichlorvos results in decreased expression of NFE2L2 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]
CTD PMID:20143881 PMID:25891459 PMID:26814074 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions
ISO Dichlorvos results in increased expression of NOS2 mRNA; Dichlorvos results in increased expression of NOS2 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 protein]
CTD PMID:22817663 PMID:24369695 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of NQO1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]
CTD PMID:26814074 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases activity
increases cleavage
multiple interactions
ISO Dichlorvos results in increased activity of PARP1 protein
Dichlorvos results in increased cleavage of PARP1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in increased activity of PARP1 protein]
CTD PMID:24231740 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PNPLA6 patatin like phospholipase domain containing 6 decreases activity ISO
EXP
Dichlorvos results in decreased activity of PNPLA6 protein CTD PMID:7713347 PMID:9268605 PMID:9586870 PMID:10776595 PMID:11282359 More... NCBI chr19:7,534,164...7,561,767
Ensembl chr19:7,534,004...7,561,764
JBrowse link
G POMC proopiomelanocortin multiple interactions
increases secretion
ISO Dichlorvos inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones]
Dichlorvos results in increased secretion of POMC protein modified form
CTD PMID:2993719 PMID:6245657 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PON1 paraoxonase 1 multiple interactions
decreases activity
decreases expression
decreases response to substance
ISO 1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)but-2-ene inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]
Dichlorvos results in decreased expression of PON1 mRNA; Dichlorvos results in decreased expression of PON1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 protein]
PON1 protein results in decreased susceptibility to Dichlorvos
CTD PMID:20412842 PMID:25891459 PMID:26814074 PMID:29098328 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PRF1 perforin 1 decreases expression EXP Dichlorvos results in decreased expression of PRF1 mRNA; Dichlorvos results in decreased expression of PRF1 protein CTD PMID:16002202 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit increases expression
multiple interactions
ISO Dichlorvos results in increased expression of PRKDC mRNA; Dichlorvos results in increased expression of PRKDC protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of PRKDC mRNA]
CTD PMID:24369695 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178
JBrowse link
G PYGB glycogen phosphorylase B increases activity ISO Dichlorvos results in increased activity of PYGB protein CTD PMID:10544956 NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012
JBrowse link
G PYGL glycogen phosphorylase L increases activity ISO Dichlorvos results in increased activity of PYGL protein CTD PMID:222008 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
JBrowse link
G SNCA synuclein alpha multiple interactions
affects localization
ISO coenzyme Q10 inhibits the reaction [Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]]; Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]
Dichlorvos affects the localization of SNCA protein
CTD PMID:21073741 PMID:21843543 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
decreases activity
ISO [mitoquinone results in increased expression of SOD2 protein] which results in decreased susceptibility to Dichlorvos; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of SOD2 protein] CTD PMID:17850875 PMID:21784090 PMID:24231740 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member increases expression ISO Dichlorvos results in increased expression of TAP1 mRNA CTD PMID:21813463 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
JBrowse link
G TAT tyrosine aminotransferase multiple interactions
increases expression
ISO [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
G TF transferrin affects binding EXP
ISO
Dichlorvos binds to TF protein
Dichlorvos binds to TRF protein
CTD PMID:18930948 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TH tyrosine hydroxylase increases activity
multiple interactions
ISO Dichlorvos results in increased activity of TH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein]
CTD PMID:12186780 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G TNF tumor necrosis factor increases expression
increases secretion
ISO Dichlorvos results in increased expression of TNF mRNA; Dichlorvos results in increased expression of TNF protein
Dichlorvos results in increased secretion of TNF protein
CTD PMID:21964614 PMID:22817663 PMID:23053939 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 decreases expression
multiple interactions
increases expression
ISO Dichlorvos results in decreased expression of TP53 mRNA
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 protein]
Dichlorvos results in increased expression of TP53 mRNA; Dichlorvos results in increased expression of TP53 protein
CTD PMID:23053939 PMID:24369695 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TUBB tubulin beta class I increases phosphorylation ISO Dichlorvos results in increased phosphorylation of TUBB protein CTD PMID:11282359 PMID:16635102 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538
JBrowse link
G UGP2 UDP-glucose pyrophosphorylase 2 decreases activity ISO Dichlorvos results in decreased activity of UGP2 protein CTD PMID:222008 NCBI chr 2:63,840,969...63,891,560
Ensembl chr 2:63,840,952...63,891,562
JBrowse link
G XAB2 XPA binding protein 2 affects response to substance EXP XAB2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:22102698 NCBI chr19:7,619,525...7,629,545
Ensembl chr19:7,619,525...7,629,545
JBrowse link
monocrotophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 increases expression ISO Monocrotophos results in increased expression of ABCA1 mRNA CTD PMID:32267039 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ACACA acetyl-CoA carboxylase alpha increases expression
increases activity
ISO Monocrotophos results in increased expression of ACACA mRNA
Monocrotophos results in increased activity of ACACA protein
CTD PMID:32267039 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions
decreases expression
decreases activity
EXP
ISO
asoxime chloride inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]
Monocrotophos results in decreased expression of ACHE mRNA
[Dichlorvos co-treated with Monocrotophos] results in increased activity of ACHE protein; [Monocrotophos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [sodium arsenite co-treated with Dichlorvos co-treated with Monocrotophos] results in decreased activity of ACHE protein
CTD PMID:8783813 PMID:15679473 PMID:15793557 PMID:20026515 PMID:20728503 More... NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing decreases expression ISO Monocrotophos results in decreased expression of ADIPOQ protein CTD PMID:32267039 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G AHR aryl hydrocarbon receptor affects expression
increases expression
multiple interactions
EXP Monocrotophos affects the expression of AHR protein
Monocrotophos results in increased expression of AHR mRNA
[Monocrotophos co-treated with Cimetidine] results in increased expression of AHR protein; [Rifampin co-treated with Monocrotophos] results in decreased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of AHR protein
CTD PMID:22733800 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 decreases expression
multiple interactions
EXP Monocrotophos results in decreased expression of AIFM1 protein
Monocrotophos promotes the reaction [AIFM1 protein binds to NFE2L2 protein]
CTD PMID:33078895 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression
multiple interactions
EXP Monocrotophos results in increased expression of APEX1 mRNA
Monocrotophos results in increased expression of and affects the localization of APEX1 protein
CTD PMID:28887667 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO Monocrotophos results in increased expression of and affects the localization of BAX protein; resveratrol inhibits the reaction [Monocrotophos results in increased expression of BAX mRNA]; resveratrol inhibits the reaction [Monocrotophos results in increased expression of BAX protein]
Monocrotophos results in increased expression of BAX mRNA; Monocrotophos results in increased expression of BAX protein
CTD PMID:20957986 PMID:21445290 PMID:23833438 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 increases expression ISO Monocrotophos results in increased expression of BBC3 mRNA CTD PMID:20957986 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions
decreases expression
ISO Monocrotophos results in increased expression of BCL2 mRNA; Monocrotophos results in increased expression of BCL2 protein
resveratrol inhibits the reaction [Monocrotophos results in decreased expression of BCL2 mRNA]; resveratrol inhibits the reaction [Monocrotophos results in decreased expression of BCL2 protein]
Monocrotophos results in decreased expression of BCL2 mRNA; Monocrotophos results in decreased expression of BCL2 protein
CTD PMID:20957986 PMID:21445290 PMID:23833438 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L2 BCL2 like 2 decreases expression ISO Monocrotophos results in decreased expression of BCL2L2 mRNA; Monocrotophos results in decreased expression of BCL2L2 protein CTD PMID:20957986 PMID:21445290 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions
ISO Monocrotophos results in increased expression of CASP3 mRNA; Monocrotophos results in increased expression of CASP3 protein; Monocrotophos results in increased expression of CASP3 protein modified form
resveratrol inhibits the reaction [Monocrotophos results in increased expression of CASP3 mRNA]; resveratrol inhibits the reaction [Monocrotophos results in increased expression of CASP3 protein]
CTD PMID:20957986 PMID:21445290 PMID:23833438 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 increases expression ISO Monocrotophos results in increased expression of CASP9 mRNA; Monocrotophos results in increased expression of CASP9 protein; Monocrotophos results in increased expression of CASP9 protein modified form CTD PMID:20957986 PMID:21445290 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases activity ISO Monocrotophos results in decreased activity of CAT protein CTD PMID:22751200 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO Monocrotophos results in increased expression of CDKN1A mRNA; Monocrotophos results in increased expression of CDKN1A protein CTD PMID:20957986 PMID:21445290 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO Monocrotophos results in increased expression of and affects the localization of CYCS protein CTD PMID:20957986 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression
multiple interactions
increases activity
ISO
EXP
Monocrotophos results in increased expression of CYP1A1 protein
[Monocrotophos co-treated with Cimetidine] results in increased expression of CYP1A1 protein; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP1A1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 protein
Monocrotophos results in increased expression of CYP1A1 mRNA; Monocrotophos results in increased expression of CYP1A1 protein
Monocrotophos results in increased activity of CYP1A1 protein
CTD PMID:21445290 PMID:22733800 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression ISO Monocrotophos results in increased expression of CYP1A2 protein CTD PMID:21445290 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions
increases expression
increases activity
EXP [Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2B6 protein; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP2B6 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 protein
Monocrotophos results in increased expression of CYP2B6 mRNA; Monocrotophos results in increased expression of CYP2B6 protein
Monocrotophos results in increased activity of CYP2B6 protein
CTD PMID:22733800 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases expression
multiple interactions
increases activity
ISO
EXP
Monocrotophos results in increased expression of CYP2E1 protein
[Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein
Monocrotophos results in increased expression of CYP2E1 mRNA; Monocrotophos results in increased expression of CYP2E1 protein
Monocrotophos results in increased activity of CYP2E1 protein
CTD PMID:21445290 PMID:22733800 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases activity
multiple interactions
increases expression
EXP Monocrotophos results in increased activity of CYP3A4 protein
[Monocrotophos co-treated with Cimetidine] results in increased expression of CYP3A4 protein; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP3A4 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP3A4 protein
Monocrotophos results in increased expression of CYP3A4 mRNA; Monocrotophos results in increased expression of CYP3A4 protein
CTD PMID:22733800 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO Monocrotophos results in increased expression of CYP7A1 mRNA CTD PMID:32267039 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G FASN fatty acid synthase increases expression
increases activity
ISO Monocrotophos results in increased expression of FASN mRNA
Monocrotophos results in increased activity of FASN protein
CTD PMID:32267039 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Monocrotophos results in increased expression of FOS protein CTD PMID:20957986 PMID:21445290 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase affects activity
increases activity
multiple interactions
ISO Monocrotophos affects the activity of G6PD protein
Monocrotophos results in increased activity of G6PD protein
[Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein
CTD PMID:24248738 PMID:32267039 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GCK glucokinase increases activity ISO Monocrotophos results in increased activity of GCK protein CTD PMID:32267039 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
JBrowse link
G GSR glutathione-disulfide reductase decreases activity
multiple interactions
affects activity
ISO Monocrotophos results in decreased activity of GSR protein
[Monocrotophos co-treated with quinalphos] affects the activity of GSR protein
Monocrotophos affects the activity of GSR protein
CTD PMID:22751200 PMID:24248738 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression
multiple interactions
ISO
EXP
Monocrotophos results in increased expression of GSTP1 mRNA; Monocrotophos results in increased expression of GSTP1 protein
[Monocrotophos co-treated with Cimetidine] results in increased expression of GSTP1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 protein
CTD PMID:21445290 PMID:22733800 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Monocrotophos results in increased expression of HMGCR mRNA CTD PMID:32267039 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G IL2 interleukin 2 decreases response to substance ISO Monocrotophos results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Monocrotophos results in increased expression of JUN protein
Monocrotophos results in increased expression of and results in increased phosphorylation of JUN protein
CTD PMID:20957986 PMID:21445290 PMID:28887667 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G LDLR low density lipoprotein receptor increases expression ISO Monocrotophos results in increased expression of LDLR mRNA CTD PMID:32267039 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,462...11,133,820
JBrowse link
G LIG3 DNA ligase 3 increases expression EXP Monocrotophos results in increased expression of LIG3 mRNA CTD PMID:28887667 NCBI chr17:34,980,512...35,010,872
Ensembl chr17:34,980,512...35,009,743
JBrowse link
G LPIN1 lipin 1 increases activity ISO Monocrotophos results in increased activity of LPIN1 protein CTD PMID:32267039 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
JBrowse link
G LPL lipoprotein lipase increases expression ISO Monocrotophos results in increased expression of LPL mRNA CTD PMID:32267039 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G MAOA monoamine oxidase A decreases activity ISO Monocrotophos results in decreased activity of MAOA protein CTD PMID:12018584 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MAOB monoamine oxidase B decreases activity ISO Monocrotophos results in decreased activity of MAOB protein CTD PMID:12018584 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Monocrotophos results in decreased expression of MCL1 mRNA; Monocrotophos results in decreased expression of MCL1 protein CTD PMID:20957986 PMID:21445290 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP Monocrotophos results in increased expression of NFE2L2 protein
Monocrotophos promotes the reaction [AIFM1 protein binds to NFE2L2 protein]
CTD PMID:28887667 PMID:33078895 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 affects expression
multiple interactions
EXP Monocrotophos affects the expression of NR1I2 protein
[Monocrotophos co-treated with Cimetidine] results in increased expression of NR1I2 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein
CTD PMID:22733800 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions
increases expression
decreases expression
EXP [Monocrotophos co-treated with Cimetidine] results in increased expression of NR1I3 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 protein
Monocrotophos results in increased expression of NR1I3 mRNA; Monocrotophos results in increased expression of NR1I3 protein
Monocrotophos results in decreased expression of NR1I3 protein
CTD PMID:22733800 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase decreases expression EXP Monocrotophos results in decreased expression of OGG1 mRNA CTD PMID:28887667 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases expression EXP Monocrotophos results in increased expression of PARP1 mRNA; Monocrotophos results in increased expression of PARP1 protein CTD PMID:28887667 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression ISO Monocrotophos results in decreased expression of PPARA mRNA CTD PMID:32267039 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression ISO Monocrotophos results in increased expression of PPARG mRNA CTD PMID:32267039 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G SCARB1 scavenger receptor class B member 1 increases expression ISO Monocrotophos results in increased expression of SCARB1 mRNA CTD PMID:32267039 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression ISO Monocrotophos results in increased expression of SREBF1 mRNA CTD PMID:32267039 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 increases expression ISO Monocrotophos results in increased expression of SREBF2 mRNA CTD PMID:32267039 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,079...41,907,307
JBrowse link
G TH tyrosine hydroxylase multiple interactions
increases activity
ISO Mifepristone inhibits the reaction [Monocrotophos results in increased activity of TH protein] CTD PMID:22305719 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G TNF tumor necrosis factor increases expression ISO Monocrotophos results in increased expression of TNF protein CTD PMID:32267039 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 increases expression ISO Monocrotophos results in increased expression of TP53 mRNA; Monocrotophos results in increased expression of TP53 protein; Monocrotophos results in increased expression of TRP53 mRNA; Monocrotophos results in increased expression of TRP53 protein CTD PMID:20957986 PMID:21445290 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
tetrachlorvinphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) decreases activity EXP Tetrachlorvinphos metabolite results in decreased activity of ACHE protein CTD PMID:30625376 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G AR androgen receptor multiple interactions EXP Tetrachlorvinphos inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Tetrachlorvinphos binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP Tetrachlorvinphos binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP
ISO
Tetrachlorvinphos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 PMID:33049310 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP
ISO
Tetrachlorvinphos binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25336
    role 25263
      application 24495
        solvent 18151
          phosphoric acid 9003
            phosphoric acid derivative 8701
              organic phosphate 8700
                alkenyl phosphate 117
                  dichlorvos 84
                  monocrotophos 51
                  tetrachlorvinphos 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 25336
    subatomic particle 25302
      composite particle 25302
        hadron 25302
          baryon 25302
            nucleon 25302
              atomic nucleus 25302
                atom 25302
                  main group element atom 25195
                    p-block element atom 25195
                      chalcogen 24191
                        oxygen atom 24086
                          oxygen molecular entity 24086
                            hydroxides 23290
                              oxoacid 22259
                                pnictogen oxoacid 11518
                                  phosphorus oxoacid 10172
                                    phosphoric acids 9003
                                      phosphoric acid 9003
                                        phosphoric acid derivative 8701
                                          phosphate 8701
                                            organic phosphate 8700
                                              alkenyl phosphate 117
                                                dichlorvos 84
                                                monocrotophos 51
                                                tetrachlorvinphos 6
paths to the root