CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: quinizarin
Accession: CHEBI:37487
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Definition: A dihydroxyanthraquinone having the two hydroxy substituents at the 1- and 4-positions; formally derived from anthraquinone by replacement of two hydrogen atoms by hydroxy groups
Synonyms: exact_synonym: 1,4-dihydroxyanthracene-9,10-dione
related_synonym: 1,4-Dihydroxyanthrachinon; 1,4-dihydroxy-9,10-anthraquinone; 1,4-dihydroxyanthra-9,10-quinone; 1,4-dihydroxyanthraquinone; Chinizarin; Formula=C14H8O4; InChI=1S/C14H8O4/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6,15-16H; InChIKey=GUEIZVNYDFNHJU-UHFFFAOYSA-N; SMILES=Oc1ccc(O)c2C(=O)c3ccccc3C(=O)c12; quinizarine
xref: Beilstein:1914036; CAS:81-64-1; Gmelin:5759
xref_mesh: MESH:C034890
xref: PMID:1650428; PMID:24434150; PMID:25956560; PMID:26178874; PMID:26695300; Reaxys:1914036; Wikipedia:1\,4-Dihydroxyanthraquinone
G
Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
1,4-dihydroxyanthraquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD
PMID:19269596
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Alb
albumin
affects binding
ISO
1,4-dihydroxyanthraquinone binds to ALB protein
CTD
PMID:16404478
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Esr1
estrogen receptor 1
multiple interactions
ISO
1,4-dihydroxyanthraquinone binds to and results in increased activity of ESR1 protein
CTD
PMID:20707409
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases glucuronidation
ISO
UGT1A1 protein results in increased glucuronidation of 1,4-dihydroxyanthraquinone
CTD
PMID:14557274
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
increases glucuronidation
ISO
UGT1A9 protein results in increased glucuronidation of 1,4-dihydroxyanthraquinone
CTD
PMID:14557274
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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