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Accession:CHEBI:3745 term browser browse the term
Definition:A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic.
Synonyms:exact_synonym: methyl 7-chloro-6,7,8-trideoxy-6-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)-1-thio-D-glycero-alpha-D-galacto-octopyranoside
 related_synonym: 7(S)-Chloro-7-deoxylincomycin;   7-CDL;   Cleocin (TN);   Formula=C18H33ClN2O5S;   InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9?,10-,11+,12?,13+,14-,15-,16-,18-/m1/s1;   InChIKey=KDLRVYVGXIQJDK-NOWPCOIGSA-N;   Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside;   SMILES=CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
 alt_id: CHEBI:47331
 xref: CAS:18323-44-9;   DrugBank:DB01190;   HMDB:HMDB0015321;   KEGG:C06914;   KEGG:C13684;   KEGG:D00277;   KEGG:D02132
 xref_mesh: MESH:D002981
 xref: PMID:11691576;   PMID:18695329;   PMID:24310902;   Reaxys:5624049;   Wikipedia:Clindamycin

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clindamycin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:6480464
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:6480464
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:6480464
clindamycin phosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        xenobiotic 18412
          clindamycin 4
            clindamycin phosphate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18475
                              organic divalent group 18468
                                organodiyl group 18468
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic acid 18034
                                        carboacyl group 17190
                                          univalent carboacyl group 17190
                                            carbamoyl group 16928
                                              carboxamide 16928
                                                monocarboxylic acid amide 14575
                                                  pyrrolidinecarboxamide 6
                                                    lincomycin 5
                                                      clindamycin 4
                                                        clindamycin phosphate 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.