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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tropane alkaloid
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Accession:CHEBI:37332 term browser browse the term
Synonyms:related_synonym: tropane alkaloids
 alt_id: CHEBI:27154;   CHEBI:27155

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(S)-atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Hyoscyamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,584,189...12,628,489
Ensembl chr17:12,584,132...12,628,488 		JBrowse link
Anatoxin a term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 multiple interactions ISO anatoxin a inhibits the reaction [iodo-alpha-bungarotoxin binds to CHRNA7 protein] CTD PMID:19448648 NCBI chr 7:63,098,692...63,212,526
Ensembl chr 7:63,098,692...63,212,569 		JBrowse link
atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions
decreases activity		 ISO Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein		 CTD PMID:24014644 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616 		JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 2:31,688,244...31,807,093
Ensembl chr 2:31,688,376...31,804,227 		JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP		 Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]		 CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 PMID:21787676 PMID:22783142 PMID:23047022 PMID:24881594 PMID:26751814 PMID:31794810 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466 		JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance EXP ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr16:35,154,494...35,305,743
Ensembl chr16:35,154,877...35,305,738 		JBrowse link
G Aqp5 aquaporin 5 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr15:99,591,028...99,594,829
Ensembl chr15:99,590,782...99,594,829 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898 		JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr 8:111,710,474...111,743,849
Ensembl chr 8:111,710,474...111,743,809 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX		 CTD PMID:17963125 PMID:22981459 NCBI chr 3:73,635,805...73,708,436
Ensembl chr 3:73,635,808...73,708,415 		JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions EXP BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr12:105,563,172...105,595,244
Ensembl chr12:105,563,226...105,595,237 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302 		JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit multiple interactions ISO Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr 1:154,390,806...154,884,785
Ensembl chr 1:154,390,731...154,884,501 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha affects activity ISO Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357 		JBrowse link
G Casp3 caspase 3 increases expression ISO Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689 		JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518 		JBrowse link
G Ccna1 cyclin A1 increases expression
multiple interactions		 ISO Atropine results in increased expression of CCNA1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA		 CTD PMID:17390078 NCBI chr 3:55,045,469...55,057,634
Ensembl chr 3:55,045,469...55,055,501 		JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr17:47,505,051...47,599,689
Ensembl chr17:47,505,051...47,599,691 		JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions		 ISO Atropine results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA		 CTD PMID:17390078 NCBI chr 7:38,097,984...38,107,490
Ensembl chr 7:38,097,984...38,107,534 		JBrowse link
G Ccne2 cyclin E2 multiple interactions
increases expression		 ISO [Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Atropine results in increased expression of CCNE2 mRNA		 CTD PMID:17390078 NCBI chr 4:11,190,433...11,204,779
Ensembl chr 4:11,191,351...11,204,779 		JBrowse link
G Cd40 CD40 antigen multiple interactions ISO Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948 		JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression		 ISO [Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Atropine results in increased expression of CDC20 mRNA		 CTD PMID:17390078 NCBI chr 4:118,432,901...118,437,343
Ensembl chr 4:118,432,901...118,437,352 		JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr11:98,907,709...98,923,942
Ensembl chr11:98,907,801...98,923,940 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression		 ISO [Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Atropine results in increased expression of CDK1 mRNA		 CTD PMID:17390078 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr 8:93,166,072...93,197,804
Ensembl chr 8:93,166,068...93,197,838 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions
decreases activity		 EXP
ISO		 Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]		 CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr19:8,664,005...8,683,606
Ensembl chr19:8,663,789...8,683,587 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 6:36,387,991...36,528,638
Ensembl chr 6:36,388,084...36,528,414 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac multiple interactions
decreases activity		 ISO Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein		 CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr13:9,875,486...10,361,062
Ensembl chr13:9,875,486...10,360,847 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding		 ISO [WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] CTD PMID:16709648 NCBI chr 2:91,922,189...91,929,835
Ensembl chr 2:91,927,249...91,928,688 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr 2:112,478,733...112,536,361
Ensembl chr 2:112,479,171...112,480,769 		JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions
affects binding		 ISO Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]		 CTD PMID:15733544 PMID:21791372 NCBI chr 2:181,022,311...181,043,579
Ensembl chr 2:181,018,380...181,043,546 		JBrowse link
G Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) affects binding
multiple interactions		 ISO Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]		 CTD PMID:15733544 PMID:21791372 NCBI chr 3:89,753,448...89,764,632
Ensembl chr 3:89,746,195...89,764,632 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
[Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein		 CTD PMID:12039681 PMID:12906840 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396 		JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507 		JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr11:70,000,592...70,010,109
Ensembl chr11:70,000,595...70,012,301 		JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984 		JBrowse link
G Egr2 early growth response 2 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr10:67,534,469...67,542,188
Ensembl chr10:67,535,475...67,542,188 		JBrowse link
G Ezr ezrin multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr17:6,738,131...6,782,780
Ensembl chr17:6,738,041...6,782,784 		JBrowse link
G F2 coagulation factor II multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414 		JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr13:95,601,780...95,618,466
Ensembl chr13:95,601,803...95,618,487 		JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions		 ISO Atropine results in increased expression of FOS protein
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]		 CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273 		JBrowse link
G Ghrl ghrelin multiple interactions ISO Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 6:113,716,119...113,719,911
Ensembl chr 6:113,716,119...113,719,880 		JBrowse link
G Glra1 glycine receptor, alpha 1 subunit multiple interactions ISO Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr11:55,514,239...55,608,198
Ensembl chr11:55,514,238...55,608,198 		JBrowse link
G Grm4 glutamate receptor, metabotropic 4 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr17:27,422,387...27,513,826
Ensembl chr17:27,422,387...27,521,403 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981 		JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222 		JBrowse link
G Junb jun B proto-oncogene multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr 8:84,976,909...84,978,748
Ensembl chr 8:84,974,484...84,978,718
Ensembl chr 8:84,974,484...84,978,718 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 2:55,411,798...55,598,145
Ensembl chr 2:55,435,970...55,598,145 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr 5:75,574,987...75,656,722
Ensembl chr 5:75,574,916...75,656,722 		JBrowse link
G Ltf lactotransferrin multiple interactions ISO Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 9:111,019,292...111,042,766
Ensembl chr 9:111,019,271...111,042,767 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions
increases expression		 ISO [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA		 CTD PMID:17390078 NCBI chr16:15,623,897...15,637,400
Ensembl chr16:15,623,897...15,637,400 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression
multiple interactions		 ISO Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA		 CTD PMID:17390078 NCBI chr 1:128,331,575...128,359,705
Ensembl chr 1:128,331,590...128,359,664 		JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr11:4,938,754...4,948,064
Ensembl chr11:4,938,754...4,948,064 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr11:59,541,569...59,566,955
Ensembl chr11:59,541,568...59,566,956 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254 		JBrowse link
G Notch4 notch 4 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr17:34,564,286...34,588,543
Ensembl chr17:34,564,268...34,588,503 		JBrowse link
G Nppa natriuretic peptide type A affects activity ISO Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079 		JBrowse link
G Oprl1 opioid receptor-like 1 multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 2:181,715,000...181,720,985
Ensembl chr 2:181,715,016...181,720,985 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314 		JBrowse link
G Pnoc prepronociceptin multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr14:65,400,673...65,425,564
Ensembl chr14:65,400,673...65,425,472 		JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr15:73,205,102...73,423,820
Ensembl chr15:73,205,102...73,423,280 		JBrowse link
G Pxn paxillin multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr 5:115,491,970...115,555,987
Ensembl chr 5:115,506,676...115,555,987 		JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr11:120,721,468...120,723,969
Ensembl chr11:120,721,470...120,723,969 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130 		JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions ISO Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr17:12,648,874...12,675,838
Ensembl chr17:12,648,869...12,675,829 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr17:12,584,189...12,628,489
Ensembl chr17:12,584,132...12,628,488 		JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 increases uptake
multiple interactions		 ISO SLC22A3 protein results in increased uptake of Atropine
Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]		 CTD PMID:16263091 NCBI chr17:12,419,972...12,507,704
Ensembl chr17:12,418,960...12,507,704 		JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 multiple interactions ISO Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr11:53,983,115...54,030,040
Ensembl chr11:53,983,123...54,028,090 		JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,343,400...61,378,842
Ensembl chr11:61,343,401...61,378,345 		JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,301,627...61,342,860
Ensembl chr11:61,301,631...61,342,860 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr11:117,966,079...117,970,336
Ensembl chr11:117,966,079...117,970,047 		JBrowse link
G Spn sialophorin increases response to substance EXP SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr 7:127,123,637...127,145,552
Ensembl chr 7:127,132,232...127,137,823 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007 		JBrowse link
G Trio triple functional domain (PTPRF interacting) multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr15:27,730,649...28,025,848
Ensembl chr15:27,730,651...28,025,848 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases response to substance EXP TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 1:14,872,644...14,918,862
Ensembl chr 1:14,872,648...14,918,862 		JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions ISO [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 3:102,777,398...102,789,082
Ensembl chr 3:102,775,465...102,782,718 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688 		JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,584,189...12,628,489
Ensembl chr17:12,584,132...12,628,488 		JBrowse link
cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase affects expression ISO Cocaine affects the expression of AACS mRNA CTD PMID:20187946 NCBI chr 5:125,475,873...125,517,405
Ensembl chr 5:125,475,814...125,517,410 		JBrowse link
G Aadac arylacetamide deacetylase decreases expression ISO Cocaine results in decreased expression of AADAC mRNA CTD PMID:17898221 NCBI chr 3:60,031,788...60,040,157
Ensembl chr 3:60,025,717...60,040,160 		JBrowse link
G Aanat arylalkylamine N-acetyltransferase affects response to substance EXP AANAT protein affects the susceptibility to Cocaine CTD PMID:12138020 NCBI chr11:116,591,721...116,597,680
Ensembl chr11:116,586,432...116,597,680 		JBrowse link
G Abat 4-aminobutyrate aminotransferase increases response to substance EXP ABAT mRNA results in increased susceptibility to Cocaine CTD PMID:10850552 NCBI chr16:8,513,429...8,621,568
Ensembl chr16:8,513,429...8,621,568 		JBrowse link
G Abca4 ATP-binding cassette, sub-family A (ABC1), member 4 decreases expression ISO Cocaine results in decreased expression of ABCA4 mRNA CTD PMID:27899881 NCBI chr 3:122,043,891...122,180,070
Ensembl chr 3:122,044,443...122,180,123 		JBrowse link
G Abca5 ATP-binding cassette, sub-family A (ABC1), member 5 multiple interactions EXP HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA] CTD PMID:17988634 NCBI chr11:110,269,369...110,337,723
Ensembl chr11:110,269,369...110,337,716 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 affects expression ISO Cocaine affects the expression of ABCC3 mRNA CTD PMID:20187946 NCBI chr11:94,343,295...94,393,017
Ensembl chr11:94,343,295...94,392,997 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 affects expression ISO Cocaine affects the expression of ABCC5 mRNA CTD PMID:20187946 NCBI chr16:20,331,303...20,426,428
Ensembl chr16:20,331,303...20,426,394 		JBrowse link
G Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 affects expression ISO Cocaine affects the expression of ABCC9 mRNA CTD PMID:20187946 NCBI chr 6:142,587,862...142,702,766
Ensembl chr 6:142,587,862...142,702,315 		JBrowse link
G Abcd4 ATP-binding cassette, sub-family D (ALD), member 4 affects expression ISO Cocaine affects the expression of ABCD4 mRNA CTD PMID:20187946 NCBI chr12:84,601,869...84,617,485
Ensembl chr12:84,601,464...84,617,413 		JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression EXP Cocaine results in decreased expression of ABHD1 mRNA CTD PMID:18355967 NCBI chr 5:30,950,066...30,955,095
Ensembl chr 5:30,950,066...30,955,091 		JBrowse link
G Abhd14a abhydrolase domain containing 14A affects expression ISO Cocaine affects the expression of ABHD14A mRNA CTD PMID:20187946 NCBI chr 9:106,440,051...106,451,203
Ensembl chr 9:106,440,051...106,447,678 		JBrowse link
G Abhd17a abhydrolase domain containing 17A affects expression ISO Cocaine affects the expression of ABHD17A mRNA CTD PMID:20187946 NCBI chr10:80,583,649...80,590,341
Ensembl chr10:80,583,654...80,590,341 		JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase affects expression EXP Cocaine affects the expression of ABL1 mRNA CTD PMID:15681117 NCBI chr 2:31,688,244...31,807,093
Ensembl chr 2:31,688,376...31,804,227 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression EXP Cocaine results in increased expression of ACAA1 mRNA CTD PMID:18355967 NCBI chr 9:119,148,043...119,157,093
Ensembl chr 9:119,148,023...119,157,093 		JBrowse link
G Acan aggrecan affects expression ISO Cocaine affects the expression of ACAN mRNA CTD PMID:20187946 NCBI chr 7:79,053,226...79,115,099
Ensembl chr 7:79,053,483...79,115,099 		JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 multiple interactions ISO ACE inhibits the reaction [Cocaine affects the abundance of Dinoprostone]; ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr11:105,967,948...105,989,964
Ensembl chr11:105,967,945...105,989,964 		JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects expression EXP Cocaine affects the expression of ACIN1 mRNA CTD PMID:15681117 NCBI chr14:54,642,161...54,686,965
Ensembl chr14:54,642,161...54,686,931 		JBrowse link
G Ackr2 atypical chemokine receptor 2 affects expression ISO Cocaine affects the expression of ACKR2 mRNA CTD PMID:20187946 NCBI chr 9:121,898,355...121,911,075
Ensembl chr 9:121,898,355...121,911,074 		JBrowse link
G Aco2 aconitase 2, mitochondrial increases expression EXP Cocaine results in increased expression of ACO2 protein modified form CTD PMID:24096156 NCBI chr15:81,872,463...81,915,137
Ensembl chr15:81,872,309...81,915,133 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression ISO Cocaine affects the expression of ACSL5 mRNA CTD PMID:20187946 NCBI chr19:55,251,861...55,296,628
Ensembl chr19:55,251,938...55,297,720 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression ISO Cocaine results in decreased expression of ACSS1 mRNA CTD PMID:27899881 NCBI chr 2:150,618,111...150,668,240
Ensembl chr 2:150,618,105...150,668,500 		JBrowse link
G Actg2 actin, gamma 2, smooth muscle, enteric decreases expression ISO Cocaine results in decreased expression of ACTG2 mRNA CTD PMID:20948987 NCBI chr 6:83,512,909...83,536,251
Ensembl chr 6:83,512,905...83,536,265 		JBrowse link
G Actn2 actinin alpha 2 increases expression ISO Cocaine results in increased expression of ACTN2 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr13:12,269,426...12,340,732
Ensembl chr13:12,269,426...12,340,760 		JBrowse link
G Acvr1c activin A receptor, type IC increases expression ISO Cocaine results in increased expression of ACVR1C mRNA CTD PMID:17898221 NCBI chr 2:58,267,453...58,357,896
Ensembl chr 2:58,267,453...58,357,895 		JBrowse link
G Acy3 aspartoacylase (aminoacylase) 3 affects expression ISO Cocaine affects the expression of ACY3 mRNA CTD PMID:20187946 NCBI chr19:3,986,570...3,990,007
Ensembl chr19:3,986,570...3,990,007 		JBrowse link
G Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) decreases expression ISO Cocaine results in decreased expression of ADAM19 mRNA CTD PMID:17898221 NCBI chr11:46,054,502...46,147,347
Ensembl chr11:46,055,992...46,147,343 		JBrowse link
G Adam1a a disintegrin and metallopeptidase domain 1a multiple interactions EXP HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA] CTD PMID:17988634 NCBI chr 5:121,518,604...121,521,695
Ensembl chr 5:121,518,576...121,545,482 		JBrowse link
G Adamts19 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 decreases expression ISO Cocaine results in decreased expression of ADAMTS19 mRNA CTD PMID:27899881 NCBI chr18:58,835,992...59,053,682
Ensembl chr18:58,836,667...59,054,060 		JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression ISO Cocaine results in decreased expression of ADAT2 mRNA CTD PMID:17898221 NCBI chr10:13,552,907...13,563,376
Ensembl chr10:13,552,894...13,563,376 		JBrowse link
G Adcy2 adenylate cyclase 2 affects expression ISO Cocaine affects the expression of ADCY2 mRNA CTD PMID:20187946 NCBI chr13:68,620,043...68,999,600
Ensembl chr13:68,620,043...68,999,541 		JBrowse link
G Adcy8 adenylate cyclase 8 affects expression ISO Cocaine affects the expression of ADCY8 mRNA CTD PMID:20187946 NCBI chr15:64,699,035...64,922,296
Ensembl chr15:64,697,084...64,922,296 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 multiple interactions
increases expression		 EXP ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA] CTD PMID:29673861 NCBI chr17:93,198,245...93,206,541
Ensembl chr17:93,199,017...93,206,537 		JBrowse link
G Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 multiple interactions
increases expression		 EXP alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA] CTD PMID:29673861 NCBI chr 6:55,451,501...55,501,455
Ensembl chr 6:55,451,978...55,501,451 		JBrowse link
G Adgra1 adhesion G protein-coupled receptor A1 multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA CTD PMID:18355967 NCBI chr 7:139,834,097...139,878,088
Ensembl chr 7:139,834,174...139,878,088 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 affects expression ISO Cocaine affects the expression of ADGRE1 mRNA CTD PMID:20187946 NCBI chr17:57,358,581...57,483,529
Ensembl chr17:57,358,691...57,483,527 		JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO Cocaine results in decreased expression of ADGRF1 mRNA CTD PMID:17898221 NCBI chr17:43,270,283...43,325,876
Ensembl chr17:43,270,329...43,324,737 		JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression ISO Cocaine affects the expression of ADGRL1 mRNA CTD PMID:20187946 NCBI chr 8:83,900,098...83,941,954
Ensembl chr 8:83,900,105...83,941,954 		JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 affects expression ISO Cocaine affects the expression of ADGRL3 mRNA CTD PMID:20187946 NCBI chr 5:81,019,085...81,827,825
Ensembl chr 5:81,020,138...81,825,133 		JBrowse link
G Adora1 adenosine A1 receptor affects expression
affects response to substance		 ISO
EXP		 Cocaine affects the expression of ADORA1 mRNA; Cocaine affects the expression of ADORA1 protein
ADORA1 affects the susceptibility to Cocaine		 CTD PMID:12358776 PMID:19092996 NCBI chr 1:134,199,215...134,235,457
Ensembl chr 1:134,199,223...134,235,431 		JBrowse link
G Adora2a adenosine A2a receptor increases response to substance EXP ADORA2A results in increased susceptibility to Cocaine CTD PMID:16123743 NCBI chr10:75,316,877...75,334,792
Ensembl chr10:75,316,877...75,334,784 		JBrowse link
G Adora2b adenosine A2b receptor affects expression ISO Cocaine affects the expression of ADORA2B mRNA CTD PMID:20187946 NCBI chr11:62,248,984...62,266,452
Ensembl chr11:62,248,984...62,266,453 		JBrowse link
G Adra1b adrenergic receptor, alpha 1b increases response to substance EXP ADRA1B gene results in increased susceptibility to Cocaine CTD PMID:14556232 NCBI chr11:43,774,605...43,901,250
Ensembl chr11:43,774,606...43,901,210 		JBrowse link
G Adrb1 adrenergic receptor, beta 1 multiple interactions
affects expression		 ISO Betaxolol affects the reaction [Cocaine affects the expression of ADRB1 protein]; Betaxolol inhibits the reaction [Cocaine affects the expression of ADRB1 protein] CTD PMID:17513029 PMID:18596687 NCBI chr19:56,722,117...56,725,150
Ensembl chr19:56,722,199...56,733,113 		JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression ISO Cocaine results in increased expression of AFF4 mRNA CTD PMID:17898221 NCBI chr11:53,350,640...53,421,830
Ensembl chr11:53,350,833...53,421,830 		JBrowse link
G Afmid arylformamidase increases expression ISO Cocaine results in increased expression of AFMID mRNA CTD PMID:17898221 NCBI chr11:117,825,503...117,839,908
Ensembl chr11:117,825,924...117,839,908 		JBrowse link
G Afp alpha fetoprotein increases expression ISO Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 NCBI chr 5:90,490,714...90,508,907
Ensembl chr 5:90,490,737...90,508,907 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 affects expression ISO Cocaine affects the expression of AGAP2 mRNA CTD PMID:20187946 NCBI chr10:127,075,269...127,093,170
Ensembl chr10:127,075,284...127,093,169 		JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 multiple interactions
affects response to substance		 EXP AGO2 protein affects the reaction [Cocaine results in increased expression of MIR130A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR136 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR137 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR138-1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR148B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR154 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR181A1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR186 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR301B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR324 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR337 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR369 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376C mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR380 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR384 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR467B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR488 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR500 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR544 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR665 mRNA]
AGO2 protein affects the susceptibility to Cocaine		 CTD PMID:20643829 NCBI chr15:73,101,625...73,184,947
Ensembl chr15:73,095,844...73,184,935 		JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Cocaine results in decreased expression of AIF1L mRNA CTD PMID:15009677 NCBI chr 2:31,950,303...31,973,442
Ensembl chr 2:31,950,139...31,973,442 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 affects expression
increases expression		 EXP
ISO		 Cocaine affects the expression of AIFM1 mRNA
Cocaine results in increased expression of AIFM1 mRNA		 CTD PMID:15681117 PMID:18000554 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563 		JBrowse link
G Aifm2 apoptosis-inducing factor, mitochondrion-associated 2 affects expression EXP Cocaine affects the expression of AIFM2 mRNA CTD PMID:15681117 NCBI chr10:61,715,263...61,739,260
Ensembl chr10:61,715,263...61,739,260 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Cocaine results in decreased expression of AK1 mRNA CTD PMID:15009677 NCBI chr 2:32,621,758...32,635,058
Ensembl chr 2:32,621,758...32,635,058 		JBrowse link
G Ak3 adenylate kinase 3 affects expression ISO Cocaine affects the expression of AK3 mRNA CTD PMID:20187946 NCBI chr19:28,995,053...29,048,080
Ensembl chr19:29,020,833...29,047,961 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression ISO Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 NCBI chr 6:37,529,978...37,574,921
Ensembl chr 6:37,530,173...37,568,815 		JBrowse link
G Akr1e1 aldo-keto reductase family 1, member E1 affects expression ISO Cocaine affects the expression of AKR1E1 mRNA CTD PMID:20187946 NCBI chr13:4,591,123...4,609,164
Ensembl chr13:4,590,750...4,609,174 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 affects expression
multiple interactions
increases phosphorylation		 ISO
EXP		 Cocaine affects the expression of AKT1 mRNA
[Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein
Cocaine results in increased phosphorylation of AKT1 protein
Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]		 CTD PMID:18702665 PMID:20187946 PMID:25933444 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO Cocaine results in increased expression of ALCAM mRNA CTD PMID:17898221 NCBI chr16:52,248,996...52,453,081
Ensembl chr16:52,248,996...52,454,074 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial multiple interactions ISO [[CVT-10216 results in decreased activity of ALDH2 protein] which results in increased abundance of Tetrahydropapaveroline] inhibits the reaction [Cocaine results in increased abundance of and results in increased secretion of Dopamine]; [ALDH2 protein affects the abundance of Tetrahydropapaveroline] which affects the susceptibility to Cocaine; ALDH2 protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:20729865 NCBI chr 5:121,566,027...121,593,824
Ensembl chr 5:121,566,027...121,593,824 		JBrowse link
G Ambra1 autophagy/beclin 1 regulator 1 decreases expression ISO Cocaine results in decreased expression of AMBRA1 mRNA CTD PMID:17898221 NCBI chr 2:91,730,138...91,918,849
Ensembl chr 2:91,730,134...91,918,849 		JBrowse link
G Amh anti-Mullerian hormone increases expression ISO Cocaine results in increased expression of AMH mRNA CTD PMID:17898221 NCBI chr10:80,805,240...80,807,679
Ensembl chr10:80,805,243...80,807,648 		JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 affects expression ISO Cocaine affects the expression of AMIGO1 mRNA CTD PMID:20187946 NCBI chr 3:108,186,289...108,192,286
Ensembl chr 3:108,186,335...108,192,286 		JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression ISO Cocaine affects the expression of AMIGO3 mRNA CTD PMID:20187946 NCBI chr 9:108,053,159...108,055,701
Ensembl chr 9:108,053,159...108,055,701 		JBrowse link
G Amn1 antagonist of mitotic exit network 1 decreases expression ISO Cocaine results in decreased expression of AMN1 mRNA CTD PMID:17898221 NCBI chr 6:149,157,261...149,188,712
Ensembl chr 6:149,157,147...149,188,712 		JBrowse link
G Ankrd54 ankyrin repeat domain 54 affects expression ISO Cocaine affects the expression of ANKRD54 mRNA CTD PMID:20187946 NCBI chr15:79,053,094...79,062,927
Ensembl chr15:79,053,094...79,062,893 		JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Cocaine results in decreased expression of ANKS1B mRNA CTD PMID:17898221 NCBI chr10:89,872,915...90,973,300
Ensembl chr10:89,873,509...90,973,300 		JBrowse link
G Anxa7 annexin A7 affects expression ISO Cocaine affects the expression of ANXA7 mRNA CTD PMID:20187946 NCBI chr14:20,455,261...20,480,133
Ensembl chr14:20,455,260...20,480,133 		JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression ISO Cocaine results in increased expression of AP1AR mRNA CTD PMID:17898221 NCBI chr 3:127,807,007...127,837,523
Ensembl chr 3:127,807,007...127,837,523 		JBrowse link
G Ap2b1 adaptor-related protein complex 2, beta 1 subunit affects expression ISO Cocaine affects the expression of AP2B1 mRNA CTD PMID:20187946 NCBI chr11:83,298,719...83,405,035
Ensembl chr11:83,299,024...83,405,035 		JBrowse link
G Ap2m1 adaptor-related protein complex 2, mu 1 subunit increases expression ISO Cocaine results in increased expression of AP2M1 protein CTD PMID:25100957 NCBI chr16:20,535,480...20,544,909
Ensembl chr16:20,535,478...20,544,909 		JBrowse link
G Ap2s1 adaptor-related protein complex 2, sigma 1 subunit decreases expression ISO Cocaine results in decreased expression of AP2S1 mRNA CTD PMID:15009677 NCBI chr 7:16,738,444...16,749,290
Ensembl chr 7:16,738,410...16,749,294 		JBrowse link
G Ap5m1 adaptor-related protein complex 5, mu 1 subunit affects expression ISO Cocaine affects the expression of AP5M1 mRNA CTD PMID:20187946 NCBI chr14:49,066,408...49,094,114
Ensembl chr14:49,066,097...49,094,234 		JBrowse link
G Apcs serum amyloid P-component increases expression ISO Cocaine results in increased expression of APCS protein CTD PMID:12714198 NCBI chr 1:172,893,961...172,895,054
Ensembl chr 1:172,893,961...172,895,041 		JBrowse link
G Aph1a aph1 homolog A, gamma secretase subunit affects expression ISO Cocaine affects the expression of APH1A mRNA CTD PMID:20187946 NCBI chr 3:95,893,921...95,898,592
Ensembl chr 3:95,893,969...95,898,288 		JBrowse link
G Aplnr apelin receptor increases expression ISO Cocaine results in increased expression of APLNR mRNA CTD PMID:17898221 NCBI chr 2:85,136,360...85,139,923
Ensembl chr 2:85,136,225...85,139,923 		JBrowse link
G Apol11a apolipoprotein L 11a decreases expression ISO Cocaine results in decreased expression of APOL11A mRNA CTD PMID:27899881 NCBI chr15:77,508,129...77,517,874
Ensembl chr15:77,508,271...77,518,051 		JBrowse link
G Apol8 apolipoprotein L 8 increases expression ISO Cocaine results in increased expression of APOL2 mRNA CTD PMID:17205118 NCBI chr15:77,745,109...77,757,062
Ensembl chr15:77,747,798...77,757,003 		JBrowse link
G Apold1 apolipoprotein L domain containing 1 affects expression ISO Cocaine affects the expression of APOLD1 mRNA CTD PMID:20187946 NCBI chr 6:134,982,001...134,986,836
Ensembl chr 6:134,981,718...134,986,836 		JBrowse link
G Apoo apolipoprotein O increases expression ISO Cocaine results in increased expression of APOO protein CTD PMID:25100957 NCBI chr  X:94,367,010...94,417,093
Ensembl chr  X:94,367,117...94,417,093 		JBrowse link
G App amyloid beta (A4) precursor protein decreases expression
increases expression		 ISO Cocaine results in decreased expression of APP mRNA
Cocaine results in increased expression of APP mRNA		 CTD PMID:15009677 PMID:16710320 PMID:17898221 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 increases expression ISO Cocaine results in increased expression of APPL1 mRNA CTD PMID:17898221 NCBI chr14:26,918,986...26,970,611
Ensembl chr14:26,918,988...26,971,232 		JBrowse link
G Arc activity regulated cytoskeletal-associated protein affects expression
increases expression
multiple interactions		 ISO Cocaine affects the expression of ARC mRNA
Cocaine results in increased expression of ARC mRNA; Cocaine results in increased expression of ARC protein
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]		 CTD PMID:7722525 PMID:12117546 PMID:15254092 PMID:17851536 PMID:18311559 PMID:18361437 PMID:20187946 PMID:24810662 NCBI chr15:74,669,081...74,672,570
Ensembl chr15:74,669,083...74,672,570 		JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression ISO Cocaine results in decreased expression of ARF4 protein CTD PMID:25100957 NCBI chr14:26,638,134...26,656,842
Ensembl chr14:26,638,074...26,665,084 		JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression ISO Cocaine results in increased expression of ARHGAP1 protein CTD PMID:25100957 NCBI chr 2:91,650,118...91,672,325
Ensembl chr 2:91,649,860...91,672,326 		JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Cocaine results in decreased expression of ARHGAP29 mRNA CTD PMID:12629581 NCBI chr 3:121,953,113...122,016,677
Ensembl chr 3:121,952,541...122,016,753 		JBrowse link
G Arhgap30 Rho GTPase activating protein 30 increases expression ISO Cocaine results in increased expression of ARHGAP30 mRNA CTD PMID:17898221 NCBI chr 1:171,388,960...171,410,240
Ensembl chr 1:171,388,954...171,410,298 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 decreases expression ISO Cocaine results in decreased expression of ARHGAP44 protein CTD PMID:25100957 NCBI chr11:65,002,039...65,162,972
Ensembl chr11:65,002,039...65,162,961 		JBrowse link
G Arhgap5 Rho GTPase activating protein 5 increases expression ISO Cocaine results in increased expression of ARHGAP5 mRNA CTD PMID:17898221 NCBI chr12:52,503,763...52,571,978
Ensembl chr12:52,503,972...52,571,975 		JBrowse link
G Arhgap9 Rho GTPase activating protein 9 decreases expression ISO Cocaine results in decreased expression of ARHGAP9 mRNA CTD PMID:17898221 NCBI chr10:127,321,913...127,329,947
Ensembl chr10:127,321,964...127,329,943 		JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 affects expression ISO Cocaine affects the expression of ARHGEF1 mRNA CTD PMID:20187946 NCBI chr 7:24,902,986...24,926,594
Ensembl chr 7:24,902,912...24,926,594 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor (GEF7) affects expression ISO Cocaine affects the expression of ARHGEF7 mRNA CTD PMID:20187946 NCBI chr 8:11,728,001...11,835,219
Ensembl chr 8:11,727,721...11,835,219 		JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 affects expression ISO Cocaine affects the expression of ARMCX6 mRNA CTD PMID:20187946 NCBI chr  X:134,748,455...134,756,666
Ensembl chr  X:134,748,461...134,751,417 		JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP Cocaine results in decreased expression of ARNTL mRNA CTD PMID:15994025 NCBI chr 7:113,178,471...113,314,126
Ensembl chr 7:113,207,465...113,314,126 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression ISO Cocaine results in increased expression of ARPC1A protein CTD PMID:25100957 NCBI chr 5:145,083,869...145,108,756
Ensembl chr 5:145,083,830...145,108,761 		JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions ISO Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP19 protein] CTD PMID:11268215 NCBI chr 9:75,037,614...75,060,313
Ensembl chr 9:75,037,614...75,060,313 		JBrowse link
G Arpp21 cyclic AMP-regulated phosphoprotein, 21 multiple interactions ISO Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP21 protein] CTD PMID:11268215 NCBI chr 9:112,065,091...112,236,288
Ensembl chr 9:112,065,091...112,235,938 		JBrowse link
G Art5 ADP-ribosyltransferase 5 increases expression ISO Cocaine results in increased expression of ART5 mRNA CTD PMID:17898221 NCBI chr 7:102,096,879...102,100,291
Ensembl chr 7:102,096,879...102,109,489 		JBrowse link
G As3mt arsenite methyltransferase affects expression ISO Cocaine affects the expression of AS3MT mRNA CTD PMID:20187946 NCBI chr19:46,707,157...46,741,099
Ensembl chr19:46,707,458...46,741,099 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain1 decreases expression ISO Cocaine results in decreased expression of ASAP1 mRNA CTD PMID:17898221 NCBI chr15:64,086,840...64,382,941
Ensembl chr15:64,086,857...64,382,919 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression ISO Cocaine results in increased expression of ATAD1 mRNA CTD PMID:17898221 NCBI chr19:32,672,558...32,739,787
Ensembl chr19:32,671,638...32,739,786 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression ISO Cocaine results in decreased expression of ATAD5 mRNA CTD PMID:17898221 NCBI chr11:80,089,379...80,135,797
Ensembl chr11:80,089,400...80,135,794 		JBrowse link
G Ate1 arginyltransferase 1 increases expression ISO Cocaine results in increased expression of ATE1 mRNA CTD PMID:17898221 NCBI chr 7:130,391,493...130,520,619
Ensembl chr 7:130,391,493...130,520,369 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
decreases expression		 ISO Cocaine results in increased expression of ATF3 mRNA
Cocaine results in decreased expression of ATF3 mRNA		 CTD PMID:23644055 PMID:27899881 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Cocaine results in increased expression of ATF4; Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214 PMID:23644055 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541 		JBrowse link
G Atf6 activating transcription factor 6 affects expression ISO Cocaine affects the expression of ATF6 mRNA CTD PMID:23644055 NCBI chr 1:170,704,457...170,868,585
Ensembl chr 1:170,704,674...170,867,771 		JBrowse link
G Atf7 activating transcription factor 7 affects expression EXP Cocaine affects the expression of ATF7 mRNA CTD PMID:15681117 NCBI chr15:102,525,946...102,625,464
Ensembl chr15:102,525,946...102,625,464 		JBrowse link
G Atg2b autophagy related 2B affects expression ISO Cocaine affects the expression of ATG2B mRNA CTD PMID:20187946 NCBI chr12:105,613,539...105,685,297
Ensembl chr12:105,616,136...105,685,211 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase affects expression ISO Cocaine affects the expression of ATG4B mRNA CTD PMID:20187946 NCBI chr 1:93,754,905...93,789,606
Ensembl chr 1:93,751,500...93,790,610 		JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
increases expression		 EXP EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740 		JBrowse link
G Atp10a ATPase, class V, type 10A decreases expression ISO Cocaine results in decreased expression of ATP10A mRNA CTD PMID:17898221 PMID:27899881 NCBI chr 7:58,656,142...58,830,244
Ensembl chr 7:58,656,166...58,829,420 		JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide affects expression EXP Cocaine affects the expression of ATP1A1 mRNA CTD PMID:18355967 NCBI chr 3:101,576,219...101,604,707
Ensembl chr 3:101,576,219...101,604,684 		JBrowse link
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide increases expression
affects expression		 ISO Cocaine results in increased expression of ATP1A3 mRNA
Cocaine affects the expression of ATP1A3 mRNA		 CTD PMID:16076954 PMID:20187946 NCBI chr 7:24,978,167...25,006,077
Ensembl chr 7:24,978,167...25,005,958 		JBrowse link
G Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide increases expression ISO Cocaine results in increased expression of ATP1B2 mRNA CTD PMID:16076954 NCBI chr11:69,599,728...69,605,978
Ensembl chr11:69,599,736...69,605,942 		JBrowse link
G Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide increases expression
multiple interactions		 EXP Cocaine results in increased expression of ATP1B3 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]		 CTD PMID:18355967 NCBI chr 9:96,332,655...96,364,431
Ensembl chr 9:96,332,655...96,364,442 		JBrowse link
G Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 affects expression ISO Cocaine affects the expression of ATP5F1A protein CTD PMID:19393250 NCBI chr18:77,773,768...77,782,869
Ensembl chr18:77,773,729...77,782,869 		JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit decreases expression ISO Cocaine results in decreased expression of ATP5F1B protein CTD PMID:17075605 NCBI chr10:128,083,307...128,090,388
Ensembl chr10:128,083,273...128,090,391 		JBrowse link
G Atp5e ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit affects expression ISO Cocaine affects the expression of ATP5F1E mRNA CTD PMID:20187946 NCBI chr 2:174,461,075...174,464,101
Ensembl chr 2:174,461,072...174,464,105 		JBrowse link
G Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) decreases expression
affects expression		 ISO Cocaine results in decreased expression of ATP5MC3 mRNA
Cocaine affects the expression of ATP5MC3 mRNA		 CTD PMID:12629581 PMID:20187946 NCBI chr 2:73,908,447...73,912,464
Ensembl chr 2:73,908,447...73,911,326 		JBrowse link
G Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D affects expression ISO Cocaine affects the expression of ATP5H mRNA CTD PMID:12358776 NCBI chr11:115,415,691...115,419,919
Ensembl chr11:115,415,689...115,419,962 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b affects expression ISO Cocaine affects the expression of ATP5PB mRNA CTD PMID:20187946 NCBI chr 3:105,942,698...105,959,263
Ensembl chr 3:105,942,698...105,960,099 		JBrowse link
G Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D affects expression ISO Cocaine affects the expression of ATP6V1D mRNA CTD PMID:20187946 NCBI chr12:78,842,982...78,862,008
Ensembl chr12:78,840,725...78,861,638 		JBrowse link
G Atp8b2 ATPase, class I, type 8B, member 2 increases expression
multiple interactions		 EXP Cocaine results in increased expression of ATP8B2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]		 CTD PMID:18355967 NCBI chr 3:89,939,481...89,963,338
Ensembl chr 3:89,939,481...89,963,508 		JBrowse link
G Atp9b ATPase, class II, type 9B affects response to substance ISO ATP9B gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr18:80,734,141...80,934,081
Ensembl chr18:80,734,141...80,934,060 		JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA CTD PMID:18355967 NCBI chr 4:115,784,828...115,811,923
Ensembl chr 4:115,784,812...115,822,655 		JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 NCBI chr  X:105,797,615...105,929,372
Ensembl chr  X:105,797,615...105,929,403 		JBrowse link
G Atxn1 ataxin 1 affects expression ISO Cocaine affects the expression of ATXN1 mRNA CTD PMID:20187946 NCBI chr13:45,549,755...45,964,991
Ensembl chr13:45,549,755...45,965,008 		JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Cocaine results in decreased expression of ATXN3 mRNA CTD PMID:12629581 NCBI chr12:101,918,901...101,959,121
Ensembl chr12:101,918,901...101,958,246 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc decreases expression ISO Cocaine results in decreased expression of AZGP1 mRNA CTD PMID:17898221 NCBI chr 5:137,981,521...137,990,233
Ensembl chr 5:137,981,520...137,990,233 		JBrowse link
G Baalc brain and acute leukemia, cytoplasmic decreases expression EXP Cocaine results in decreased expression of BAALC mRNA CTD PMID:18355967 NCBI chr15:38,933,909...38,951,264
Ensembl chr15:38,933,144...38,952,912 		JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 increases expression ISO Cocaine results in increased expression of BACH1 mRNA CTD PMID:17898221 NCBI chr16:87,698,954...87,733,346
Ensembl chr16:87,698,945...87,733,346 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 affects expression EXP Cocaine affects the expression of BACH2 mRNA CTD PMID:15681117 NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Bad BCL2-associated agonist of cell death affects expression EXP Cocaine affects the expression of BAD mRNA CTD PMID:15681117 NCBI chr19:6,941,861...6,951,905
Ensembl chr19:6,941,861...6,951,899 		JBrowse link
G Bag1 BCL2-associated athanogene 1 affects expression EXP Cocaine affects the expression of BAG1 mRNA CTD PMID:15681117 NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294 		JBrowse link
G Bag3 BCL2-associated athanogene 3 affects expression
increases expression		 EXP
ISO		 Cocaine affects the expression of BAG3 mRNA
Cocaine results in increased expression of BAG3 mRNA		 CTD PMID:15681117 PMID:27899881 NCBI chr 7:128,523,583...128,546,981
Ensembl chr 7:128,523,616...128,546,981 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression ISO Cocaine affects the expression of BAMBI mRNA CTD PMID:20187946 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 affects expression ISO Cocaine affects the expression of BASP1 mRNA CTD PMID:20187946 NCBI chr15:25,363,277...25,413,764
Ensembl chr15:25,363,277...25,413,764 		JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
increases activity
affects expression		 ISO
EXP		 Cocaine results in increased expression of BAX mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]
Cocaine results in increased activity of BAX protein
Cocaine affects the expression of BAX mRNA		 CTD PMID:11392460 PMID:15681117 PMID:15685203 PMID:17084983 PMID:17635674 PMID:18974856 PMID:20948987 PMID:29673861 PMID:30393195 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions
increases expression		 EXP [SMARCA5 protein co-treated with BAZ1B protein] results in increased susceptibility to Cocaine; Cocaine promotes the reaction [BAZ1B protein binds to SPHKAP gene]; Cocaine results in increased expression of and affects the activity of BAZ1B protein
Cocaine results in increased expression of BAZ1B mRNA		 CTD PMID:27053203 NCBI chr 5:135,187,323...135,246,131
Ensembl chr 5:135,187,264...135,246,129 		JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression ISO Cocaine results in increased expression of BAZ2B mRNA CTD PMID:17898221 NCBI chr 2:59,899,363...60,209,913
Ensembl chr 2:59,899,363...60,209,839 		JBrowse link
G Bcap31 B cell receptor associated protein 31 affects expression ISO Cocaine affects the expression of BCAP31 mRNA CTD PMID:20187946 NCBI chr  X:73,686,178...73,717,815
Ensembl chr  X:73,686,178...73,716,175 		JBrowse link
G Bcat1 branched chain aminotransferase 1, cytosolic affects expression ISO Cocaine affects the expression of BCAT1 mRNA CTD PMID:20187946 NCBI chr 6:144,993,835...145,076,157
Ensembl chr 6:144,993,835...145,076,184 		JBrowse link
G Bche butyrylcholinesterase affects metabolic processing
multiple interactions
increases hydrolysis
increases metabolic processing
decreases response to substance
affects hydrolysis
decreases metabolic processing
affects degradation		 ISO
EXP		 BCHE protein affects the metabolism of Cocaine
[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of Benzoic Acid; [BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl ester
[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of Benzoic Acid; [BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl ester
BCHE protein mutant form results in increased metabolism of Cocaine; BCHE protein results in increased metabolism of Cocaine
BCHE protein mutant form results in decreased susceptibility to Cocaine
BCHE protein modified form results in increased hydrolysis of Cocaine; BCHE protein mutant form results in increased hydrolysis of Cocaine
BCHE protein affects the hydrolysis of Cocaine
BCHE protein mutant form results in decreased metabolism of Cocaine
BCHE protein mutant form affects the degradation of Cocaine		 CTD PMID:572161 PMID:16275916 PMID:17989928 PMID:18514178 PMID:18514640 PMID:19067679 PMID:20060817 PMID:20219449 PMID:20971807 PMID:22917637 PMID:22960160 PMID:24582612 PMID:25814464 PMID:27154495 PMID:30080993 NCBI chr 3:73,635,805...73,708,436
Ensembl chr 3:73,635,808...73,708,415 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 affects expression
multiple interactions
decreases expression
increases phosphorylation
increases expression		 EXP
ISO		 Cocaine affects the expression of BCL2 mRNA
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]
Cocaine results in increased phosphorylation of BCL2 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
Cocaine results in decreased expression of BCL2 mRNA; Cocaine results in decreased expression of BCL2 protein
Cocaine results in increased expression of BCL2 protein		 CTD PMID:11392460 PMID:15365088 PMID:15681117 PMID:15685203 PMID:17084983 PMID:18974856 PMID:19183502 PMID:19879923 PMID:29673861 PMID:30393195 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274 		JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Cocaine results in increased expression of BCL2L1 mRNA; Cocaine results in increased expression of BCL2L1 mRNA alternative form
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]		 CTD PMID:16076954 PMID:29673861 PMID:30393195 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728 		JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) increases expression ISO Cocaine results in increased expression of BCL2L11 mRNA CTD PMID:16076954 NCBI chr 2:128,126,038...128,162,547
Ensembl chr 2:128,126,038...128,162,547 		JBrowse link
G Bdnf brain derived neurotrophic factor decreases response to substance
increases expression
decreases activity
affects expression
multiple interactions
decreases expression
increases response to substance		 ISO
EXP		 BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of BDNF mRNA
Cocaine results in decreased activity of BDNF protein
Cocaine results in increased expression of BDNF protein
Cocaine affects the expression of BDNF exon; Cocaine affects the expression of BDNF mRNA; Cocaine affects the expression of BDNF protein
BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]; Cocaine affects the activity of and affects the expression of BDNF protein; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]; Cocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine; BDNF results in decreased susceptibility to Cocaine
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; (+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; Cocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Cocaine results in decreased expression of BDNF mRNA; Cocaine results in decreased expression of BDNF protein
BDNF results in increased susceptibility to Cocaine		 CTD PMID:12099907 PMID:14973246 PMID:16423334 PMID:17194538 PMID:17618281 PMID:18311559 PMID:18355967 PMID:19321768 PMID:20554863 PMID:20711185 PMID:20810894 PMID:20826313 PMID:24358339 PMID:26558777 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007 		JBrowse link
G Begain brain-enriched guanylate kinase-associated affects expression ISO Cocaine affects the expression of BEGAIN mRNA CTD PMID:20187946 NCBI chr12:109,032,181...109,068,242
Ensembl chr12:109,032,187...109,068,217 		JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 increases expression ISO Cocaine results in increased expression of BHLHE22 mRNA CTD PMID:17898221 NCBI chr 3:18,054,325...18,057,514
Ensembl chr 3:18,054,174...18,057,517 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO Cocaine affects the expression of BHLHE40 mRNA CTD PMID:20187946 NCBI chr 6:108,660,629...108,666,925
Ensembl chr 6:108,660,629...108,666,925 		JBrowse link
G Bid BH3 interacting domain death agonist affects expression EXP Cocaine affects the expression of BID mRNA CTD PMID:15681117 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853 		JBrowse link
G Bik BCL2-interacting killer affects expression EXP Cocaine affects the expression of BIK mRNA CTD PMID:15681117 NCBI chr15:83,526,790...83,544,635
Ensembl chr15:83,526,862...83,544,634 		JBrowse link
G Bmp2k BMP2 inducible kinase affects expression ISO Cocaine affects the expression of BMP2K mRNA CTD PMID:20187946 NCBI chr 5:96,997,672...97,091,048
Ensembl chr 5:96,997,689...97,091,867 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) increases expression ISO Cocaine results in increased expression of BMPR2 mRNA CTD PMID:17898221 NCBI chr 1:59,764,279...59,878,081
Ensembl chr 1:59,763,400...59,879,014 		JBrowse link
G Bnip2 BCL2/adenovirus E1B interacting protein 2 affects expression EXP Cocaine affects the expression of BNIP2 mRNA CTD PMID:15681117 NCBI chr 9:69,989,438...70,011,659
Ensembl chr 9:69,989,466...70,008,317 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 affects expression EXP Cocaine affects the expression of BNIP3 mRNA CTD PMID:15681117 NCBI chr 7:138,890,836...138,909,506
Ensembl chr 7:138,890,836...138,909,519 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like affects expression EXP Cocaine affects the expression of BNIP3L mRNA CTD PMID:15681117 NCBI chr14:66,985,238...67,008,877
Ensembl chr14:66,985,239...67,008,877 		JBrowse link
G Brd4 bromodomain containing 4 multiple interactions
increases expression		 EXP
ISO		 (+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]
Cocaine results in increased expression of BRD4 protein		 CTD PMID:26558777 NCBI chr17:32,196,272...32,284,743
Ensembl chr17:32,196,274...32,284,722 		JBrowse link
G Bscl2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) affects expression ISO Cocaine affects the expression of BSCL2 mRNA CTD PMID:20187946 NCBI chr19:8,837,467...8,848,683
Ensembl chr19:8,837,467...8,848,683 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 affects expression ISO Cocaine affects the expression of BST1 mRNA CTD PMID:20187946 NCBI chr 5:43,818,880...43,843,468
Ensembl chr 5:43,818,885...43,843,986 		JBrowse link
G Btbd9 BTB (POZ) domain containing 9 increases expression ISO Cocaine results in increased expression of BTBD9 mRNA CTD PMID:17898221 NCBI chr17:30,215,524...30,582,621
Ensembl chr17:30,215,524...30,576,488 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression ISO Cocaine affects the expression of BTG2 mRNA CTD PMID:20187946 NCBI chr 1:134,074,865...134,079,155
Ensembl chr 1:134,075,170...134,079,120 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase decreases expression ISO Cocaine results in decreased expression of BTK mRNA CTD PMID:17898221 NCBI chr  X:134,542,334...134,583,628
Ensembl chr  X:134,542,336...134,583,570 		JBrowse link
G C1qbp complement component 1, q subcomponent binding protein decreases expression ISO Cocaine results in decreased expression of C1QBP protein CTD PMID:25100957 NCBI chr11:70,977,846...70,983,026
Ensembl chr11:70,977,836...70,983,026 		JBrowse link
G C1qtnf1 C1q and tumor necrosis factor related protein 1 affects expression ISO Cocaine affects the expression of C1QTNF1 mRNA CTD PMID:20187946 NCBI chr11:118,428,457...118,451,782
Ensembl chr11:118,428,203...118,449,963 		JBrowse link
G C1qtnf4 C1q and tumor necrosis factor related protein 4 decreases expression ISO Cocaine results in decreased expression of C1QTNF4 mRNA CTD PMID:17898221 NCBI chr 2:90,882,788...90,890,526
Ensembl chr 2:90,885,860...90,890,525 		JBrowse link
G C2cd3 C2 calcium-dependent domain containing 3 decreases expression ISO Cocaine results in decreased expression of C2CD3 mRNA CTD PMID:17898221 NCBI chr 7:100,372,229...100,470,159
Ensembl chr 7:100,372,233...100,470,152 		JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression ISO Cocaine results in decreased expression of C2CD4D mRNA CTD PMID:27899881 NCBI chr 3:94,362,444...94,364,567
Ensembl chr 3:94,362,438...94,364,566 		JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA CTD PMID:18355967 NCBI chr14:59,440,934...59,548,904
Ensembl chr14:59,440,972...59,585,764 		JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit affects response to substance ISO CACNA1D polymorphism affects the susceptibility to Cocaine CTD PMID:28194001 NCBI chr14:30,039,941...30,491,156
Ensembl chr14:30,039,939...30,491,455 		JBrowse link
G Cacnb3 calcium channel, voltage-dependent, beta 3 subunit affects expression ISO Cocaine affects the expression of CACNB3 mRNA CTD PMID:20187946 NCBI chr15:98,628,436...98,644,536
Ensembl chr15:98,630,840...98,644,529 		JBrowse link
G Cald1 caldesmon 1 affects expression ISO Cocaine affects the expression of CALD1 mRNA CTD PMID:20187946 NCBI chr 6:34,598,495...34,775,469
Ensembl chr 6:34,598,500...34,775,473 		JBrowse link
G Calm1 calmodulin 1 decreases expression ISO Cocaine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr12:100,199,435...100,209,824
Ensembl chr12:100,199,435...100,209,814 		JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Cocaine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr17:87,433,401...87,446,935
Ensembl chr12:100,199,435...100,209,814
Ensembl chr17:100,199,435...100,209,814 		JBrowse link
G Calr calreticulin decreases expression
multiple interactions
affects expression		 EXP
ISO		 Cocaine results in decreased expression of CALR mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]
Cocaine affects the expression of CALR mRNA		 CTD PMID:18355967 PMID:20187946 NCBI chr 8:84,842,088...84,846,931
Ensembl chr 8:84,841,850...84,846,934 		JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression ISO Cocaine results in increased expression of CALY mRNA CTD PMID:20171207 NCBI chr 7:140,069,880...140,082,571
Ensembl chr 7:140,069,880...140,082,548 		JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase I gamma multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA CTD PMID:18355967 NCBI chr 1:193,346,346...193,370,355
Ensembl chr 1:193,346,346...193,370,298 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha affects response to substance
multiple interactions
increases expression		 EXP
ISO		 CAMK2A affects the susceptibility to Cocaine
Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]
Cocaine results in increased expression of CAMK2A protein
7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]		 CTD PMID:14725635 PMID:17609678 PMID:19217379 PMID:28194001 NCBI chr18:60,925,307...60,988,152
Ensembl chr18:60,925,618...60,988,152 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II, beta decreases expression
affects expression		 ISO Cocaine results in decreased expression of CAMK2B mRNA
Cocaine affects the expression of CAMK2B mRNA		 CTD PMID:17205118 PMID:20187946 NCBI chr11:5,969,629...6,066,357
Ensembl chr11:5,969,644...6,066,362 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases response to substance
decreases response to substance		 ISO
EXP		 CAMK4 promoter SNP results in increased susceptibility to Cocaine
CAMK4 protein results in decreased susceptibility to Cocaine		 CTD PMID:19001277 NCBI chr18:32,934,941...33,195,767
Ensembl chr18:32,934,931...33,191,228 		JBrowse link
G Cap2 CAP, adenylate cyclase-associated protein, 2 (yeast) affects expression ISO Cocaine affects the expression of CAP2 mRNA CTD PMID:20187946 NCBI chr13:46,501,903...46,650,281
Ensembl chr13:46,501,848...46,650,281 		JBrowse link
G Capzb capping protein (actin filament) muscle Z-line, beta decreases expression ISO Cocaine results in decreased expression of CAPZB mRNA CTD PMID:12629581 NCBI chr 4:139,192,899...139,291,820
Ensembl chr 4:139,192,899...139,291,818 		JBrowse link
G Car4 carbonic anhydrase 4 decreases expression ISO Cocaine results in decreased expression of CAR4 mRNA CTD PMID:17898221 NCBI chr11:84,957,754...84,966,054
Ensembl chr11:84,957,786...84,966,044 		JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO Cocaine results in decreased expression of CARD11 mRNA CTD PMID:27899881 NCBI chr 5:140,872,999...141,000,596
Ensembl chr 5:140,872,990...141,000,582 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 affects expression ISO Cocaine affects the expression of CARM1 mRNA CTD PMID:20187946 NCBI chr 9:21,546,894...21,589,467
Ensembl chr 9:21,546,894...21,592,623 		JBrowse link
G Carnmt1 carnosine N-methyltransferase 1 affects expression ISO Cocaine affects the expression of CARNMT1 mRNA CTD PMID:20187946 NCBI chr19:18,670,759...18,707,201
Ensembl chr19:18,670,764...18,707,200 		JBrowse link
G Cartpt CART prepropeptide increases expression
affects expression		 ISO Cocaine results in increased expression of CARTPT mRNA
Cocaine affects the expression of CARTPT mRNA		 CTD PMID:15009677 PMID:17851536 PMID:20187946 NCBI chr13:99,898,483...99,910,179
Ensembl chr13:99,898,489...99,901,091 		JBrowse link
G Casp2 caspase 2 increases activity
increases expression		 ISO Cocaine results in increased activity of CASP2 protein
Cocaine results in increased expression of CASP2 mRNA		 CTD PMID:16076954 PMID:16638611 NCBI chr 6:42,264,902...42,282,508
Ensembl chr 6:42,264,985...42,282,508 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases cleavage
increases activity
affects expression		 ISO
EXP		 Cocaine results in increased expression of CASP3 protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]
Cocaine results in increased activity of CASP3 protein
Cocaine affects the expression of CASP3 protein
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Cocaine results in increased cleavage of and results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP3 protein]
Cocaine affects the expression of CASP3 mRNA		 CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:14741756 PMID:15365088 PMID:15681117 PMID:16179556 PMID:16638611 PMID:16686379 PMID:17084983 PMID:17635674 PMID:18974856 PMID:19183502 PMID:20600547 PMID:29673861 PMID:30393195 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase affects expression
decreases expression		 EXP
ISO		 Cocaine affects the expression of CASP4 mRNA
Cocaine results in decreased expression of CASP4 mRNA		 CTD PMID:12629581 PMID:15681117 NCBI chr 9:5,308,849...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Casp8 caspase 8 affects expression
increases activity		 EXP
ISO		 Cocaine affects the expression of CASP8 mRNA
Cocaine results in increased activity of CASP8 protein		 CTD PMID:11392460 PMID:15681117 PMID:18974856 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503 		JBrowse link
G Casp9 caspase 9 affects expression
increases activity
multiple interactions
increases expression		 EXP
ISO		 Cocaine affects the expression of CASP9 mRNA
Cocaine results in increased activity of CASP9 protein
SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP9 protein]
Cocaine affects the expression of CASP9 protein
Cocaine results in increased expression of CASP9 protein		 CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:15365088 PMID:15681117 PMID:16179556 PMID:16638611 PMID:16686379 PMID:17084983 PMID:17635674 PMID:18974856 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976 		JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 affects expression ISO Cocaine affects the expression of CASTOR1 mRNA CTD PMID:20187946 NCBI chr11:4,218,166...4,222,409
Ensembl chr11:4,218,225...4,222,409 		JBrowse link
G Cat catalase decreases activity
increases activity
increases expression		 EXP
ISO		 Cocaine results in decreased activity of CAT protein
Cocaine results in increased activity of CAT protein
Cocaine results in increased expression of CAT protein		 CTD PMID:14576513 PMID:16085363 PMID:29475069 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160 		JBrowse link
G Catsper2 cation channel, sperm associated 2 increases expression ISO Cocaine results in increased expression of CATSPER2 mRNA CTD PMID:17898221 NCBI chr 2:121,391,633...121,414,598
Ensembl chr 2:121,392,631...121,413,792 		JBrowse link
G Cbln1 cerebellin 1 precursor protein multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA CTD PMID:18355967 NCBI chr 8:87,468,853...87,472,592
Ensembl chr 8:87,468,405...87,472,609 		JBrowse link
G Ccdc127 coiled-coil domain containing 127 increases expression ISO Cocaine results in increased expression of CCDC127 mRNA CTD PMID:17898221 NCBI chr13:74,350,317...74,365,783
Ensembl chr13:74,350,309...74,365,783 		JBrowse link
G Ccdc174 coiled-coil domain containing 174 affects expression ISO Cocaine affects the expression of CCDC174 mRNA CTD PMID:20187946 NCBI chr 6:91,843,154...91,899,849
Ensembl chr 6:91,878,053...91,899,843 		JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression ISO Cocaine results in increased expression of CCDC88A mRNA CTD PMID:17898221 NCBI chr11:29,373,405...29,510,808
Ensembl chr11:29,373,658...29,510,808 		JBrowse link
G Ccdc93 coiled-coil domain containing 93 increases expression ISO Cocaine results in increased expression of CCDC93 mRNA CTD PMID:17898221 NCBI chr 1:121,431,067...121,506,460
Ensembl chr 1:121,431,049...121,506,460 		JBrowse link
G Cckbr cholecystokinin B receptor decreases expression
increases response to substance		 ISO
EXP		 Cocaine results in decreased expression of CCKBR mRNA
CCKBR protein results in increased susceptibility to Cocaine		 CTD PMID:11403953 PMID:18000554 NCBI chr 7:105,425,676...105,436,339
Ensembl chr 7:105,425,731...105,470,898 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases secretion
increases expression
multiple interactions		 ISO
EXP		 Cocaine results in increased secretion of CCL2 protein
Cocaine results in increased expression of CCL2 protein
Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]		 CTD PMID:10065903 PMID:20354174 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453 		JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 increases secretion ISO Cocaine results in increased secretion of CCL3 protein CTD PMID:10065903 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Cocaine results in decreased expression of CCN2 mRNA; Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 NCBI chr10:24,595,442...24,598,683
Ensembl chr10:24,595,442...24,598,683 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Cocaine results in increased expression of CCN3 mRNA CTD PMID:17898221 NCBI chr15:54,745,910...54,753,762
Ensembl chr15:54,745,702...54,754,039 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Cocaine results in decreased expression of CCNA2 mRNA CTD PMID:18593214 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150 		JBrowse link
G Ccnd1 cyclin D1 affects expression ISO Cocaine affects the expression of CCND1 mRNA CTD PMID:20187946 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925 		JBrowse link
G Ccnd3 cyclin D3 affects expression ISO Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 NCBI chr17:47,505,051...47,599,689
Ensembl chr17:47,505,051...47,599,691 		JBrowse link
G Ccnl1 cyclin L1 increases expression ISO Cocaine results in increased expression of CCNL1 mRNA CTD PMID:16076954 NCBI chr 3:65,945,908...65,962,029
Ensembl chr 3:65,946,151...65,958,249 		JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 increases response to substance
affects expression		 EXP
ISO		 CCR2 results in increased susceptibility to Cocaine
Cocaine affects the expression of CCR2 mRNA		 CTD PMID:20187946 PMID:20354174 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557 		JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 increases expression ISO Cocaine results in increased expression of CCR5 protein CTD PMID:16204638 NCBI chr 9:124,121,543...124,127,183
Ensembl chr 9:124,121,543...124,147,699 		JBrowse link
G Ccser1 coiled-coil serine rich 1 affects response to substance ISO CCSER1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 6:61,179,960...62,382,863
Ensembl chr 6:61,180,324...62,382,865 		JBrowse link
G Cct2 chaperonin containing Tcp1, subunit 2 (beta) affects expression ISO Cocaine affects the expression of CCT2 mRNA CTD PMID:20187946 NCBI chr10:117,050,997...117,063,852
Ensembl chr10:117,051,001...117,063,814 		JBrowse link
G Ccz1 CCZ1 vacuolar protein trafficking and biogenesis associated decreases expression ISO Cocaine results in decreased expression of CCZ1 mRNA CTD PMID:12629581 NCBI chr 5:143,987,909...144,014,883
Ensembl chr 5:143,987,909...144,014,877 		JBrowse link
G Cd180 CD180 antigen decreases expression ISO Cocaine results in decreased expression of CD180 mRNA CTD PMID:27899881 NCBI chr13:102,693,547...102,706,631
Ensembl chr13:102,693,558...102,739,629 		JBrowse link
G Cd276 CD276 antigen affects expression ISO Cocaine affects the expression of CD276 mRNA CTD PMID:20187946 NCBI chr 9:58,524,300...58,555,033
Ensembl chr 9:58,524,298...58,555,437 		JBrowse link
G Cd4 CD4 antigen multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA CTD PMID:18355967 NCBI chr 6:124,864,693...124,888,247
Ensembl chr 6:124,864,692...124,888,221 		JBrowse link
G Cd44 CD44 antigen decreases expression ISO Cocaine results in decreased expression of CD44 mRNA CTD PMID:18000554 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665 		JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) affects expression ISO Cocaine affects the expression of CD47 mRNA CTD PMID:20187946 NCBI chr16:49,851,328...49,912,503
Ensembl chr16:49,800,533...49,915,010 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) affects expression ISO Cocaine affects the expression of CD74 mRNA CTD PMID:20187946 NCBI chr18:60,803,849...60,812,652
Ensembl chr18:60,803,848...60,812,652 		JBrowse link
G Cd81 CD81 antigen increases response to substance
increases expression
affects response to substance		 ISO
EXP		 CD81 protein results in increased susceptibility to Cocaine
Cocaine results in increased expression of CD81 mRNA
CD81 protein affects the susceptibility to Cocaine		 CTD PMID:11178868 PMID:12113778 PMID:15715673 NCBI chr 7:143,052,750...143,067,930
Ensembl chr 7:143,052,739...143,067,934 		JBrowse link
G Cd93 CD93 antigen decreases expression ISO Cocaine results in decreased expression of CD93 mRNA CTD PMID:17898221 NCBI chr 2:148,436,651...148,443,535
Ensembl chr 2:148,436,640...148,443,563 		JBrowse link
G Cdc14b CDC14 cell division cycle 14B decreases expression ISO Cocaine results in decreased expression of CDC14B mRNA CTD PMID:17898221 NCBI chr13:64,192,545...64,274,988
Ensembl chr13:64,189,268...64,275,290 		JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO Cocaine results in increased expression of CDC25A mRNA CTD PMID:17898221 NCBI chr 9:109,875,518...109,893,895
Ensembl chr 9:109,875,579...109,893,895 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Cocaine results in decreased expression of CDH1 mRNA CTD PMID:12629581 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246 		JBrowse link
G Cdh16 cadherin 16 affects expression ISO Cocaine affects the expression of CDH16 mRNA CTD PMID:20187946 NCBI chr 8:104,601,915...104,624,396
Ensembl chr 8:104,601,911...104,624,396 		JBrowse link
G Cdh17 cadherin 17 decreases expression ISO Cocaine results in decreased expression of CDH17 mRNA CTD PMID:12629581 NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895 		JBrowse link
G Cdk18 cyclin-dependent kinase 18 affects expression ISO Cocaine affects the expression of CDK18 mRNA CTD PMID:20187946 NCBI chr 1:132,113,547...132,139,698
Ensembl chr 1:132,112,237...132,139,684 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression EXP Cocaine affects the expression of CDK4 mRNA CTD PMID:18355967 NCBI chr10:127,063,535...127,067,288
Ensembl chr10:127,063,534...127,067,920 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 affects expression
increases expression
decreases expression		 ISO Cocaine affects the expression of CDK5 mRNA; Cocaine affects the expression of CDK5 protein
Cocaine results in increased expression of CDK5 mRNA; Cocaine results in increased expression of CDK5 protein
Cocaine results in decreased expression of CDK5 protein		 CTD PMID:11268215 PMID:12787079 PMID:16263094 PMID:17339080 PMID:17680995 PMID:20187946 NCBI chr 5:24,407,597...24,423,587
Ensembl chr 5:24,418,241...24,423,530 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) multiple interactions
increases expression
decreases expression		 EXP
ISO		 CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK3 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
Cocaine results in increased expression of CDK5R1 mRNA; Cocaine results in increased expression of CDK5R1 protein
Cocaine results in decreased expression of CDK5R1 protein		 CTD PMID:11268215 PMID:15665076 PMID:16263094 NCBI chr11:80,477,023...80,481,184
Ensembl chr11:80,477,023...80,481,184 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) increases expression ISO Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727 		JBrowse link
G Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 affects expression ISO Cocaine affects the expression of CEACAM3 mRNA CTD PMID:20187946 NCBI chr 7:24,777,167...24,784,656
Ensembl chr 7:24,777,206...24,784,657 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Cocaine results in increased expression of CEL mRNA CTD PMID:27899881 NCBI chr 2:28,555,819...28,563,403
Ensembl chr 2:28,555,795...28,563,403 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
affects binding		 ISO CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol]; Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin]
CES1 protein results in increased hydrolysis of Cocaine
Cocaine binds to CES1 protein		 CTD PMID:8930175 PMID:9311626 PMID:12679808 PMID:12773168 PMID:25445008 NCBI chr 8:93,166,072...93,197,804
Ensembl chr 8:93,166,068...93,197,838 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
decreases expression
increases hydrolysis		 ISO Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of Heroin]
Cocaine results in decreased expression of CES2 mRNA
CES2 protein results in increased hydrolysis of Cocaine		 CTD PMID:8930175 PMID:9169443 PMID:12629581 NCBI chr 8:105,000,830...105,020,410
Ensembl chr 8:105,000,853...105,021,178 		JBrowse link
G Cfh complement component factor h decreases expression ISO Cocaine results in decreased expression of CFH mRNA CTD PMID:17898221 NCBI chr 1:140,085,855...140,183,411
Ensembl chr 1:140,084,708...140,183,764 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression EXP Cocaine affects the expression of CFLAR mRNA CTD PMID:15681117 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains affects expression ISO Cocaine affects the expression of CHFR mRNA CTD PMID:20187946 NCBI chr 5:110,135,755...110,171,973
Ensembl chr 5:110,135,842...110,171,972 		JBrowse link
G Chn1 chimerin 1 affects expression ISO Cocaine affects the expression of CHN1 mRNA CTD PMID:20187946 NCBI chr 2:73,610,660...73,775,367
Ensembl chr 2:73,610,660...73,775,346 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects expression ISO Cocaine affects the expression of CHRM4 mRNA CTD PMID:20187946 NCBI chr 2:91,922,189...91,929,835
Ensembl chr 2:91,927,249...91,928,688 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 decreases response to substance ISO CHRM5 mutant form results in decreased susceptibility to Cocaine CTD PMID:20393457 NCBI chr 2:112,478,733...112,536,361
Ensembl chr 2:112,479,171...112,480,769 		JBrowse link
G Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 multiple interactions ISO Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 9:55,010,117...55,026,562
Ensembl chr 9:55,010,111...55,026,562 		JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions ISO Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 2:181,022,311...181,043,579
Ensembl chr 2:181,018,380...181,043,546 		JBrowse link
G Chrna5 cholinergic receptor, nicotinic, alpha polypeptide 5 decreases response to substance ISO CHRNA5 gene polymorphism results in decreased susceptibility to Cocaine CTD PMID:18519132 NCBI chr 9:54,980,827...55,011,420
Ensembl chr 9:54,980,880...55,007,779 		JBrowse link
G Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) multiple interactions
increases response to substance		 ISO
EXP		 Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CHRNB2 protein results in increased susceptibility to Cocaine		 CTD PMID:10336510 PMID:11282258 NCBI chr 3:89,753,448...89,764,632
Ensembl chr 3:89,746,195...89,764,632 		JBrowse link
G Chrne cholinergic receptor, nicotinic, epsilon polypeptide increases expression ISO Cocaine results in increased expression of CHRNE mRNA CTD PMID:27899881 NCBI chr11:70,614,883...70,619,213
Ensembl chr11:70,614,883...70,619,216 		JBrowse link
G Chtf8 CTF8, chromosome transmission fidelity factor 8 decreases expression ISO Cocaine results in decreased expression of CHTF8 mRNA CTD PMID:17898221 NCBI chr 8:106,883,863...106,893,593
Ensembl chr 8:106,883,863...106,893,601
Ensembl chr 8:106,883,863...106,893,601 		JBrowse link
G Churc1 churchill domain containing 1 decreases expression ISO Cocaine results in decreased expression of CHURC1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr12:76,765,538...76,783,180
Ensembl chr12:76,765,538...76,783,180 		JBrowse link
G Ciao1 cytosolic iron-sulfur protein assembly 1 affects expression ISO Cocaine affects the expression of CIAO1 mRNA CTD PMID:20187946 NCBI chr 2:127,240,938...127,247,816
Ensembl chr 2:127,240,938...127,247,816 		JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A affects expression EXP Cocaine affects the expression of CIDEA mRNA CTD PMID:15681117 NCBI chr18:67,343,564...67,367,794
Ensembl chr18:67,343,604...67,367,785 		JBrowse link
G Cideb cell death-inducing DNA fragmentation factor, alpha subunit-like effector B affects expression EXP Cocaine affects the expression of CIDEB mRNA CTD PMID:15681117 NCBI chr14:55,754,052...55,758,424
Ensembl chr14:55,754,050...55,758,458 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression ISO Cocaine results in increased expression of CISD1 protein CTD PMID:25100957 NCBI chr10:71,330,494...71,344,849
Ensembl chr10:71,330,480...71,344,954 		JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression ISO Cocaine results in increased expression of CISD2 mRNA CTD PMID:17898221 NCBI chr 3:135,406,412...135,424,039
Ensembl chr 3:135,406,412...135,423,925 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO Cocaine results in decreased expression of CITED4 mRNA CTD PMID:27899881 NCBI chr 4:120,666,563...120,667,820
Ensembl chr 4:120,666,572...120,667,820 		JBrowse link
G Ckb creatine kinase, brain multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr12:111,669,355...111,672,338
Ensembl chr12:111,669,361...111,672,338 		JBrowse link
G Ckm creatine kinase, muscle multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 7:19,411,094...19,421,583
Ensembl chr 7:19,404,776...19,422,841 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1, ubiquitous affects expression ISO Cocaine affects the expression of CKMT1 mRNA CTD PMID:20187946 NCBI chr 2:121,357,773...121,363,737
Ensembl chr 2:121,357,714...121,363,737 		JBrowse link
G Clcn7 chloride channel, voltage-sensitive 7 affects expression ISO Cocaine affects the expression of CLCN7 mRNA CTD PMID:20187946 NCBI chr17:25,133,378...25,162,103
Ensembl chr17:25,133,391...25,162,104 		JBrowse link
G Cldn11 claudin 11 decreases expression ISO Cocaine results in decreased expression of CLDN11 mRNA CTD PMID:18357522 NCBI chr 3:31,149,920...31,164,326
Ensembl chr 3:31,149,920...31,164,324 		JBrowse link
G Clec4f C-type lectin domain family 4, member f affects expression ISO Cocaine affects the expression of CLEC4F mRNA CTD PMID:20187946 NCBI chr 6:83,644,542...83,656,116
Ensembl chr 6:83,644,542...83,656,187 		JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Cocaine results in decreased expression of CLIC1 mRNA CTD PMID:18000554 NCBI chr17:35,050,243...35,058,719
Ensembl chr17:35,049,966...35,058,749 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Cocaine results in increased expression of CLIP1 mRNA CTD PMID:18000554 NCBI chr 5:123,577,794...123,684,606
Ensembl chr 5:123,577,795...123,684,618 		JBrowse link
G Clk1 CDC-like kinase 1 increases expression
multiple interactions		 EXP Cocaine results in increased expression of CLK1 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]		 CTD PMID:18355967 NCBI chr 1:58,411,988...58,424,088
Ensembl chr 1:58,410,189...58,424,066 		JBrowse link
G Clk4 CDC like kinase 4 increases expression EXP Cocaine results in increased expression of CLK4 mRNA CTD PMID:20056891 NCBI chr11:51,263,114...51,281,770
Ensembl chr11:51,261,730...51,281,766 		JBrowse link
G Clock circadian locomotor output cycles kaput increases expression EXP Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 NCBI chr 5:76,209,868...76,305,603
Ensembl chr 5:76,209,868...76,304,792 		JBrowse link
G Cltb clathrin, light polypeptide (Lcb) decreases expression ISO Cocaine results in decreased expression of CLTB mRNA CTD PMID:12629581 PMID:15009677 NCBI chr13:54,592,386...54,611,373
Ensembl chr13:54,592,401...54,611,344 		JBrowse link
G Clybl citrate lyase beta like increases expression ISO Cocaine results in increased expression of CLYBL protein CTD PMID:25100957 NCBI chr14:122,170,994...122,402,234
Ensembl chr14:122,181,704...122,402,234 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression ISO Cocaine results in increased expression of CNBD2 mRNA CTD PMID:17898221 NCBI chr 2:156,311,946...156,375,638
Ensembl chr 2:156,312,299...156,375,638 		JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 increases expression ISO Cocaine results in increased expression of CNKSR2 mRNA CTD PMID:15009677 NCBI chr  X:157,821,430...158,044,458
Ensembl chr  X:157,821,436...158,043,294 		JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) affects response to substance
increases activity
decreases response to substance
multiple interactions		 ISO
EXP		 CNR1 gene polymorphism affects the susceptibility to Cocaine; CNR1 gene SNP affects the susceptibility to Cocaine; CNR1 polymorphism affects the susceptibility to Cocaine
Cocaine results in increased activity of CNR1 protein
CNR1 mutant form results in decreased susceptibility to Cocaine
CNR1 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:9106242 PMID:16314880 PMID:17596442 PMID:19052543 PMID:20554863 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) increases expression EXP Cocaine results in increased expression of CNR2 mRNA CTD PMID:18286196 NCBI chr 4:135,895,189...135,920,219
Ensembl chr 4:135,895,394...135,920,207 		JBrowse link
G Cobll1 Cobl-like 1 increases expression EXP Cocaine results in increased expression of COBLL1 mRNA CTD PMID:27506785 NCBI chr 2:65,088,339...65,239,398
Ensembl chr 2:65,088,339...65,239,403 		JBrowse link
G Coil coilin affects expression ISO Cocaine affects the expression of COIL mRNA CTD PMID:20187946 NCBI chr11:88,973,935...88,991,613
Ensembl chr11:88,970,252...88,991,613 		JBrowse link
G Col15a1 collagen, type XV, alpha 1 affects expression ISO Cocaine affects the expression of COL15A1 mRNA CTD PMID:20187946 NCBI chr 4:47,207,655...47,313,167
Ensembl chr 4:47,208,161...47,313,167 		JBrowse link
G Col1a1 collagen, type I, alpha 1 increases expression ISO Cocaine results in increased expression of COL1A1 mRNA CTD PMID:9455993 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042 		JBrowse link
G Col3a1 collagen, type III, alpha 1 increases expression ISO Cocaine results in increased expression of COL3A1 mRNA CTD PMID:9455993 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706 		JBrowse link
G Coq6 coenzyme Q6 monooxygenase affects expression ISO Cocaine affects the expression of COQ6 mRNA CTD PMID:20187946 NCBI chr12:84,361,756...84,373,796
Ensembl chr12:84,361,657...84,373,796 		JBrowse link
G Coro7 coronin 7 multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA CTD PMID:18355967 NCBI chr16:4,626,884...4,679,720
Ensembl chr16:4,626,133...4,679,777 		JBrowse link
G Cox20 cytochrome c oxidase assembly protein 20 decreases expression ISO Cocaine results in decreased expression of COX20 mRNA CTD PMID:17898221 NCBI chr 1:178,318,095...178,322,693
Ensembl chr 1:178,319,130...178,322,693 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects expression ISO Cocaine affects the expression of COX5A mRNA CTD PMID:20187946 NCBI chr 9:57,517,328...57,532,427
Ensembl chr 9:57,521,274...57,532,426 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 affects expression
increases expression		 ISO Cocaine affects the expression of COX6A1 mRNA
Cocaine results in increased expression of COX6A1 protein		 CTD PMID:20187946 PMID:25100957 NCBI chr 5:115,345,652...115,348,958
Ensembl chr 5:115,345,642...115,348,981 		JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression ISO Cocaine results in decreased expression of COX6C mRNA CTD PMID:12629581 NCBI chr15:35,931,976...35,938,246
Ensembl chr15:35,925,886...35,938,246 		JBrowse link
G Cox7b cytochrome c oxidase subunit 7B affects expression ISO Cocaine affects the expression of COX7B mRNA CTD PMID:20187946 NCBI chr  X:106,015,700...106,022,450
Ensembl chr  X:106,015,700...106,022,450 		JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression ISO Cocaine affects the expression of COX8A mRNA CTD PMID:20187946 NCBI chr19:7,215,158...7,217,616
Ensembl chr19:7,215,153...7,217,616 		JBrowse link
G Cplx1 complexin 1 affects expression ISO Cocaine affects the expression of CPLX1 mRNA CTD PMID:20187946 NCBI chr 5:108,518,554...108,550,027
Ensembl chr 5:108,518,554...108,550,024 		JBrowse link
G Cpne8 copine VIII increases expression ISO Cocaine results in increased expression of CPNE8 mRNA CTD PMID:17898221 NCBI chr15:90,487,481...90,679,388
Ensembl chr15:90,487,482...90,679,432 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
increases phosphorylation
multiple interactions
affects phosphorylation
increases expression		 ISO
EXP		 Cocaine affects the expression of CREB1 mRNA
Cocaine results in increased phosphorylation of CREB1 protein
CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of CREB1 protein]; RPS6KA3 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
Cocaine affects the phosphorylation of CREB1 protein
Betaxolol affects the reaction [Cocaine affects the phosphorylation of CREB1 protein]; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of CREB1 protein; U 0126 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]		 CTD PMID:12595601 PMID:15470197 PMID:15665076 PMID:16219028 PMID:16339038 PMID:16710312 PMID:18596687 PMID:20187946 PMID:20810894 PMID:24358339 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548 		JBrowse link
G Crebbp CREB binding protein increases expression ISO Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 NCBI chr16:4,081,334...4,213,957
Ensembl chr16:4,081,328...4,213,997 		JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Cocaine results in increased expression of CREBRF mRNA CTD PMID:17898221 NCBI chr17:26,715,594...26,776,637
Ensembl chr17:26,715,650...26,776,635 		JBrowse link
G Crem cAMP responsive element modulator affects expression
increases expression		 EXP
ISO		 Cocaine affects the expression of CREM mRNA
Cocaine results in increased expression of CREM mRNA		 CTD PMID:18355967 PMID:27899881 NCBI chr18:3,266,354...3,337,773
Ensembl chr18:3,266,048...3,337,748 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
affects expression		 ISO Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA]; Cocaine affects the reaction [CRH protein affects the secretion of Excitatory Amino Acid Agents]; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
Cocaine affects the expression of CRH mRNA; Cocaine affects the expression of CRH protein		 CTD PMID:7796157 PMID:11597771 PMID:12782395 PMID:15930388 PMID:18596687 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein increases expression ISO Cocaine results in increased expression of CRHBP mRNA CTD PMID:27899881 NCBI chr13:95,431,376...95,444,831
Ensembl chr13:95,431,371...95,444,924 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression ISO Cocaine results in increased expression of CRHR1 protein CTD PMID:17079348 NCBI chr11:104,130,463...104,175,523
Ensembl chr11:104,132,855...104,175,523 		JBrowse link
G Crip2 cysteine rich protein 2 affects expression ISO Cocaine affects the expression of CRIP2 mRNA CTD PMID:20187946 NCBI chr12:113,140,236...113,145,506
Ensembl chr12:113,140,236...113,145,506 		JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 decreases expression ISO Cocaine results in decreased expression of CRISPLD1 mRNA CTD PMID:27899881 NCBI chr 1:17,727,029...17,767,235
Ensembl chr 1:17,727,045...17,766,344 		JBrowse link
G Crp C-reactive protein, pentraxin-related increases expression ISO Cocaine results in increased expression of CRP protein CTD PMID:11988210 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031 		JBrowse link
G Crtac1 cartilage acidic protein 1 affects expression ISO Cocaine affects the expression of CRTAC1 mRNA CTD PMID:20187946 NCBI chr19:42,283,035...42,432,966
Ensembl chr19:42,268,287...42,431,785 		JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 multiple interactions ISO [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein CTD PMID:20613834 NCBI chr 8:70,382,352...70,439,702
Ensembl chr 8:70,382,355...70,439,579 		JBrowse link
G Cry1 cryptochrome 1 (photolyase-like) decreases expression EXP Cocaine results in decreased expression of CRY1 mRNA CTD PMID:15994025 NCBI chr10:85,131,700...85,185,054
Ensembl chr10:85,131,700...85,185,064 		JBrowse link
G Cry2 cryptochrome 2 (photolyase-like) decreases expression EXP Cocaine results in decreased expression of CRY2 mRNA CTD PMID:15994025 NCBI chr 2:92,403,646...92,434,085
Ensembl chr 2:92,403,646...92,434,043 		JBrowse link
G Cryab crystallin, alpha B decreases expression
increases expression		 ISO Cocaine results in decreased expression of CRYAB mRNA
Cocaine results in increased expression of CRYAB mRNA		 CTD PMID:15009677 PMID:27899881 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636 		JBrowse link
G Crybb2 crystallin, beta B2 decreases expression ISO Cocaine results in decreased expression of CRYBB2 mRNA CTD PMID:15009677 NCBI chr 5:113,058,258...113,070,117
Ensembl chr 5:113,058,258...113,070,117 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase affects expression
decreases expression		 ISO Cocaine affects the expression of CSAD mRNA
Cocaine results in decreased expression of CSAD protein		 CTD PMID:20187946 PMID:25100957 NCBI chr15:102,176,997...102,205,052
Ensembl chr15:102,176,999...102,204,724 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) decreases expression ISO Cocaine results in decreased expression of CSF2RA mRNA CTD PMID:17898221 NCBI chr19:61,217,191...61,228,461
Ensembl chr19:61,223,957...61,228,429 		JBrowse link
G Csn3 casein kappa affects expression ISO Cocaine affects the expression of CSN3 mRNA CTD PMID:20187946 NCBI chr 5:87,925,579...87,932,550
Ensembl chr 5:87,925,579...87,932,665 		JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide decreases expression ISO Cocaine results in decreased expression of CSNK2A1 mRNA CTD PMID:12117546 NCBI chr 2:152,226,535...152,281,856
Ensembl chr 2:152,226,839...152,281,852 		JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 affects expression ISO Cocaine affects the expression of CSPG5 mRNA; Cocaine affects the expression of CSPG5 protein CTD PMID:12358776 NCBI chr 9:110,243,783...110,262,576
Ensembl chr 9:110,243,783...110,262,576 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO Cocaine results in decreased expression of CSRP2 mRNA CTD PMID:18000554 NCBI chr10:110,920,176...110,939,514
Ensembl chr10:110,919,789...110,939,622 		JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 affects expression ISO Cocaine affects the expression of CTDNEP1 mRNA CTD PMID:20187946 NCBI chr11:69,981,168...69,990,601
Ensembl chr11:69,981,156...69,990,601 		JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 affects expression
multiple interactions		 ISO Cocaine affects the expression of CTNNB1 mRNA
Cocaine deficiency promotes the reaction [SMARCA4 protein binds to CTNNB1 promoter]		 CTD PMID:20187946 PMID:27422367 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507 		JBrowse link
G Ctnnbip1 catenin beta interacting protein 1 decreases expression ISO Cocaine results in decreased expression of CTNNBIP1 mRNA CTD PMID:18000554 NCBI chr 4:149,518,241...149,566,437
Ensembl chr 4:149,518,236...149,566,437 		JBrowse link
G Ctnnd2 catenin (cadherin associated protein), delta 2 decreases expression
increases expression		 ISO Cocaine results in decreased expression of CTNND2 mRNA
Cocaine results in increased expression of CTNND2 mRNA		 CTD PMID:12629581 PMID:16076954 NCBI chr15:30,172,534...31,029,344
Ensembl chr15:30,172,593...31,029,341 		JBrowse link
G Ctrl chymotrypsin-like affects expression
increases expression		 ISO Cocaine affects the expression of CTRL mRNA
Cocaine results in increased expression of CTRL mRNA		 CTD PMID:20187946 PMID:27899881 NCBI chr 8:105,931,994...105,933,862
Ensembl chr 8:105,932,003...105,933,862 		JBrowse link
G Ctsb cathepsin B affects expression
multiple interactions
increases expression		 EXP Cocaine affects the expression of CTSB mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]		 CTD PMID:15681117 PMID:18355967 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923 		JBrowse link
G Ctsd cathepsin D affects expression
increases expression		 EXP
ISO		 Cocaine affects the expression of CTSD mRNA
Cocaine results in increased expression of CTSD protein		 CTD PMID:15681117 PMID:25100957 NCBI chr 7:142,375,910...142,387,827
Ensembl chr 7:142,375,911...142,388,038 		JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions EXP HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA] CTD PMID:17988634 NCBI chr11:88,099,146...88,194,140
Ensembl chr11:88,098,058...88,194,140 		JBrowse link
G Cul4b cullin 4B increases expression ISO Cocaine results in increased expression of CUL4B mRNA CTD PMID:15009677 NCBI chr  X:38,531,616...38,576,196
Ensembl chr  X:38,533,274...38,576,196 		JBrowse link
G Cwf19l2 CWF19-like 2, cell cycle control (S. pombe) increases expression ISO Cocaine results in increased expression of CWF19L2 mRNA CTD PMID:17898221 NCBI chr 9:3,403,592...3,479,236
Ensembl chr 9:3,403,592...3,479,236 		JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 increases expression ISO Cocaine results in increased expression of CX3CL1 mRNA CTD PMID:16076954 NCBI chr 8:94,772,180...94,782,427
Ensembl chr 8:94,772,009...94,782,427 		JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 increases secretion ISO Cocaine results in increased secretion of CXCL10 protein CTD PMID:10065903 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889 		JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases secretion ISO Cocaine results in increased secretion of CXCL8 protein CTD PMID:10065903 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067 		JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 decreases expression ISO Cocaine results in decreased expression of CXCL9 mRNA CTD PMID:17898221 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079 		JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 increases expression ISO Cocaine results in increased expression of CXCR4 protein CTD PMID:16204638 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293 		JBrowse link
G Cxxc5 CXXC finger 5 affects expression ISO Cocaine affects the expression of CXXC5 mRNA CTD PMID:20187946 NCBI chr18:35,829,379...35,861,693
Ensembl chr18:35,829,397...35,861,688 		JBrowse link
G Cyba cytochrome b-245, alpha polypeptide increases expression EXP Cocaine results in increased expression of CYBA protein CTD PMID:18952886 NCBI chr 8:122,424,771...122,432,940
Ensembl chr 8:122,424,776...122,432,930 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide increases expression
increases response to substance		 EXP Cocaine results in increased expression of CYBB protein
CYBB results in increased susceptibility to Cocaine		 CTD PMID:18952886 NCBI chr  X:9,435,252...9,487,766
Ensembl chr  X:9,435,252...9,487,771 		JBrowse link
G Cyc1 cytochrome c-1 decreases expression ISO Cocaine results in decreased expression of CYC1 mRNA CTD PMID:12629581 NCBI chr15:76,343,513...76,346,260
Ensembl chr15:76,343,523...76,346,260 		JBrowse link
G Cycs cytochrome c, somatic affects expression
multiple interactions		 EXP
ISO		 Cocaine affects the expression of CYCS mRNA
Minocycline inhibits the reaction [Cocaine results in increased secretion of CYCS protein]		 CTD PMID:15681117 PMID:21424555 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538 		JBrowse link
G Cygb cytoglobin decreases expression ISO Cocaine results in decreased expression of CYGB protein CTD PMID:25100957 NCBI chr11:116,645,595...116,654,504
Ensembl chr11:116,645,595...116,654,313 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO Cocaine results in decreased expression of CYP19A1 mRNA CTD PMID:27899881 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 EXP Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein] CTD PMID:11856816 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression ISO Cocaine affects the expression of CYP26A1 mRNA CTD PMID:20187946 NCBI chr19:37,697,738...37,701,536
Ensembl chr19:37,697,798...37,701,536 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases response to substance ISO CYP26B1 protein results in decreased susceptibility to Cocaine CTD PMID:27899881 NCBI chr 6:84,571,414...84,593,908
Ensembl chr 6:84,571,414...84,593,908 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 decreases expression ISO Cocaine results in decreased expression of CYP2C8 mRNA; Cocaine results in decreased expression of CYP2C8 protein CTD PMID:16188404 NCBI chr19:39,287,044...39,330,713
Ensembl chr19:39,269,405...39,330,713 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases expression ISO Cocaine results in decreased expression of CYP2C9 mRNA; Cocaine results in decreased expression of CYP2C9 protein CTD PMID:16188404 NCBI chr19:39,061,006...39,093,948
Ensembl chr19:39,061,015...39,093,944 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 decreases expression ISO Cocaine results in decreased expression of CYP2C9 mRNA; Cocaine results in decreased expression of CYP2C9 protein CTD PMID:16188404 NCBI chr19:39,113,898...39,186,756
Ensembl chr19:39,113,898...39,187,072 		JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 increases expression
multiple interactions		 EXP Cocaine results in increased expression of CYP2J2 protein
Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]		 CTD PMID:11856816 NCBI chr 4:96,568,424...96,592,523
Ensembl chr 4:96,568,429...96,591,578 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Cocaine results in decreased expression of CYP51 mRNA CTD PMID:12629581 NCBI chr 5:4,080,674...4,104,697
Ensembl chr 5:4,081,145...4,104,746 		JBrowse link
G Dab2ip disabled 2 interacting protein decreases expression ISO Cocaine results in decreased expression of DAB2IP mRNA CTD PMID:17898221 NCBI chr 2:35,558,446...35,730,994
Ensembl chr 2:35,558,266...35,730,994 		JBrowse link
G Dazap1 DAZ associated protein 1 affects expression ISO Cocaine affects the expression of DAZAP1 mRNA CTD PMID:20187946 NCBI chr10:80,261,362...80,288,408
Ensembl chr10:80,261,486...80,288,408 		JBrowse link
G Dbh dopamine beta hydroxylase increases response to substance
decreases response to substance		 ISO
EXP		 DBH gene polymorphism results in increased susceptibility to Cocaine
DBH gene mutant form results in decreased susceptibility to Cocaine		 CTD PMID:10673769 PMID:12555232 PMID:18083142 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200 		JBrowse link
G Dbn1 drebrin 1 multiple interactions ISO Cocaine deficiency promotes the reaction [SMARCA4 protein binds to DBN1 promoter] CTD PMID:27422367 NCBI chr13:55,473,428...55,488,126
Ensembl chr13:55,473,429...55,488,111 		JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression ISO Cocaine affects the expression of DCAF8 mRNA CTD PMID:20187946 NCBI chr 1:172,148,015...172,196,393
Ensembl chr 1:172,148,084...172,197,005 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression		 EXP
ISO		 Cocaine affects the expression of DDIT3 mRNA
Cocaine results in increased expression of DDIT3 mRNA		 CTD PMID:15681117 PMID:20187946 PMID:23644055 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288 		JBrowse link
G Ddr2 discoidin domain receptor family, member 2 decreases expression ISO Cocaine results in decreased expression of DDR2 mRNA CTD PMID:17898221 NCBI chr 1:169,972,307...170,110,836
Ensembl chr 1:169,972,307...170,110,762 		JBrowse link
G Ddx41 DEAD box helicase 41 decreases expression ISO Cocaine results in decreased expression of DDX41 mRNA CTD PMID:18000554 NCBI chr13:55,530,410...55,536,658
Ensembl chr13:55,530,410...55,536,658 		JBrowse link
G Ddx50 DExD box helicase 50 affects expression ISO Cocaine affects the expression of DDX50 mRNA CTD PMID:20187946 NCBI chr10:62,615,792...62,658,764
Ensembl chr10:62,615,895...62,651,218 		JBrowse link
G Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 increases expression ISO Cocaine results in increased expression of DDX6 mRNA CTD PMID:17898221 NCBI chr 9:44,602,983...44,640,731
Ensembl chr 9:44,604,892...44,640,731 		JBrowse link
G Deaf1 DEAF1, transcription factor decreases expression ISO Cocaine results in decreased expression of DEAF1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 7:141,297,176...141,338,869
Ensembl chr 7:141,297,180...141,327,690 		JBrowse link
G Dhh desert hedgehog affects expression ISO Cocaine affects the expression of DHH mRNA CTD PMID:20187946 NCBI chr15:98,881,615...98,898,562
Ensembl chr15:98,891,152...98,898,540 		JBrowse link
G Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 affects expression ISO Cocaine affects the expression of DHX30 mRNA CTD PMID:20187946 NCBI chr 9:110,084,319...110,117,616
Ensembl chr 9:110,084,320...110,117,830 		JBrowse link
G Dipk1b divergent protein kinase domain 1B affects expression ISO Cocaine affects the expression of DIPK1B mRNA CTD PMID:20187946 NCBI chr 2:26,628,457...26,636,497
Ensembl chr 2:26,628,457...26,636,497 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Cocaine results in increased expression of DLG2 protein CTD PMID:25100957 NCBI chr 7:90,476,188...92,449,246
Ensembl chr 7:90,476,672...92,449,247 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression
increases expression
multiple interactions
decreases response to substance
decreases expression		 ISO
EXP		 Cocaine affects the expression of DLG4 mRNA; Cocaine affects the expression of DLG4 protein
Cocaine results in increased expression of DLG4 protein
ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]
DLG4 protein results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of DLG4 mRNA		 CTD PMID:14980210 PMID:19629758 PMID:20187946 PMID:20534846 PMID:20600170 NCBI chr11:70,017,203...70,045,535
Ensembl chr11:70,016,942...70,047,522 		JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 decreases expression
multiple interactions		 EXP Cocaine results in decreased expression of DLK2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]		 CTD PMID:18355967 NCBI chr17:46,297,256...46,303,271
Ensembl chr17:46,297,421...46,303,271 		JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 affects response to substance ISO DNAH8 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr17:30,626,935...30,875,762
Ensembl chr17:30,624,354...30,877,365 		JBrowse link
G Dnm1 dynamin 1 affects expression ISO Cocaine affects the expression of DNM1 mRNA CTD PMID:20187946 NCBI chr 2:32,308,471...32,353,349
Ensembl chr 2:32,308,471...32,353,338 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases phosphorylation		 ISO
EXP		 [Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]
Cocaine results in increased phosphorylation of DNM1L protein		 CTD PMID:30158054 PMID:31494168 NCBI chr16:16,312,228...16,359,038
Ensembl chr16:16,312,230...16,358,959 		JBrowse link
G Dnm2 dynamin 2 affects expression ISO Cocaine affects the expression of DNM2 mRNA CTD PMID:20187946 NCBI chr 9:21,424,908...21,507,759
Ensembl chr 9:21,424,908...21,507,759 		JBrowse link
G Dnm3 dynamin 3 affects expression ISO Cocaine affects the expression of DNM3 mRNA CTD PMID:20187946 NCBI chr 1:161,982,450...162,478,321
Ensembl chr 1:161,982,453...162,478,034 		JBrowse link
G Dnmbp dynamin binding protein decreases expression ISO Cocaine results in decreased expression of DNMBP mRNA CTD PMID:17898221 NCBI chr19:43,846,815...43,940,232
Ensembl chr19:43,846,821...43,940,191 		JBrowse link
G Dnmt3b DNA methyltransferase 3B decreases expression
multiple interactions		 EXP Cocaine results in decreased expression of DNMT3B mRNA; Cocaine results in decreased expression of DNMT3B protein
Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA]; Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein]		 CTD PMID:22438930 NCBI chr 2:153,649,411...153,687,730
Ensembl chr 2:153,649,450...153,687,730 		JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO Cocaine results in decreased expression of DNPH1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr17:46,496,789...46,499,618
Ensembl chr17:46,496,711...46,499,624 		JBrowse link
G Dpf2 D4, zinc and double PHD fingers family 2 increases expression ISO Cocaine results in increased expression of DPF2 mRNA CTD PMID:18000554 NCBI chr19:5,896,516...5,912,871
Ensembl chr19:5,896,516...5,913,010 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions ISO [Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of DPYSL2 protein CTD PMID:19457111 NCBI chr14:66,802,864...66,911,041
Ensembl chr14:66,802,864...66,868,688 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression ISO Cocaine affects the expression of DPYSL3 mRNA CTD PMID:20187946 NCBI chr18:43,320,979...43,438,286
Ensembl chr18:43,320,984...43,438,286 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
decreases expression
affects response to substance
affects expression
increases response to substance
decreases response to substance		 ISO
EXP		 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein]; Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
Cocaine results in decreased expression of DRD1 protein
DRD1 protein affects the susceptibility to Cocaine
Cocaine affects the expression of DRD1 protein
DRD1 results in increased susceptibility to Cocaine
Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of PDYN protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of SYT7 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
DRD1 gene mutant form results in decreased susceptibility to Cocaine
[anhydroecgonine methyl ester co-treated with Cocaine] results in decreased expression of DRD1 protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]		 CTD PMID:2213551 PMID:8001143 PMID:11421588 PMID:11602327 PMID:15049517 PMID:15056714 PMID:16674926 PMID:17161392 PMID:20435100 PMID:20456009 PMID:20956312 PMID:27129946 NCBI chr13:54,051,183...54,055,658
Ensembl chr13:54,051,183...54,055,705 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression
affects response to substance
increases activity
increases expression
multiple interactions
affects expression
decreases response to substance
increases response to substance		 ISO
EXP		 Cocaine results in decreased expression of DRD2 mRNA; Cocaine results in decreased expression of DRD2 protein
DRD2 protein affects the susceptibility to Cocaine
Cocaine results in increased activity of DRD2 protein
Cocaine results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein
Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]; Methadone affects the reaction [Cocaine affects the expression of DRD2 mRNA]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]
Cocaine affects the expression of DRD2; Cocaine affects the expression of DRD2 mRNA; Cocaine affects the expression of DRD2 protein
DRD2 protein results in decreased susceptibility to Cocaine
PDYN protein affects the reaction [Cocaine affects the expression of DRD2 protein]
DRD2 results in increased susceptibility to Cocaine
DRD2 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the reaction [Raclopride binds to DRD2]		 CTD PMID:2213551 PMID:9892293 PMID:11126397 PMID:11602327 PMID:11790512 PMID:11923462 PMID:12892653 PMID:15010698 PMID:15042275 PMID:15049517 PMID:17161392 PMID:17532787 PMID:17544385 PMID:17671965 PMID:18000554 PMID:18305460 PMID:18990547 PMID:19046384 PMID:19723785 PMID:20435100 PMID:20729865 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177 		JBrowse link
G Drd3 dopamine receptor D3 decreases expression
decreases response to substance
increases expression
increases activity
affects expression
affects activity
multiple interactions
affects response to substance		 ISO
EXP		 Cocaine results in decreased expression of DRD3 protein
DRD3 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of DRD3 mRNA
Cocaine results in increased activity of DRD3 protein
Cocaine affects the expression of DRD3 protein
Cocaine affects the activity of DRD3 protein
DRD3 protein results in decreased susceptibility to Cocaine
7-hydroxy-2-N,N-dipropylaminotetralin inhibits the reaction [Cocaine affects the activity of DRD3 protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]
DRD3 affects the susceptibility to Cocaine
[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine; [3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol co-treated with Cocaine] affects the localization of DRD3 protein; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of PDYN protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of SYT7 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; DRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of PDYN protein]; SB 277011 inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine]		 CTD PMID:10523822 PMID:10943692 PMID:11120399 PMID:12099907 PMID:15056714 PMID:15100700 PMID:16026479 PMID:18566292 PMID:19046384 PMID:19217379 PMID:19723785 PMID:20435100 PMID:20456009 NCBI chr16:43,754,015...43,825,982
Ensembl chr16:43,754,026...43,822,932 		JBrowse link
G Drd4 dopamine receptor D4 increases response to substance
affects expression		 ISO DRD4 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD4 mRNA		 CTD PMID:17671965 PMID:20187946 NCBI chr 7:141,291,974...141,296,464
Ensembl chr 7:141,292,006...141,296,464 		JBrowse link
G Drd5 dopamine receptor D5 affects expression ISO Cocaine affects the expression of DRD5 mRNA CTD PMID:20187946 NCBI chr 5:38,319,509...38,322,523
Ensembl chr 5:38,319,367...38,322,518 		JBrowse link
G Drp2 dystrophin related protein 2 affects expression ISO Cocaine affects the expression of DRP2 protein CTD PMID:19393250 NCBI chr  X:134,404,124...134,456,574
Ensembl chr  X:134,404,551...134,456,573 		JBrowse link
G Dsp desmoplakin increases expression ISO Cocaine results in increased expression of DSP protein CTD PMID:17075605 NCBI chr13:38,151,294...38,198,577
Ensembl chr13:38,151,294...38,198,577 		JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
increases phosphorylation		 ISO Cocaine affects the expression of DUSP1 mRNA
Cocaine results in increased phosphorylation of DUSP1 protein		 CTD PMID:18822274 PMID:20187946 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128 		JBrowse link
G Dusp5 dual specificity phosphatase 5 affects expression
increases expression		 ISO Cocaine affects the expression of CPG21 mRNA
Cocaine results in increased expression of DUSP5 mRNA		 CTD PMID:20187946 PMID:27899881 NCBI chr19:53,529,145...53,541,809
Ensembl chr19:53,529,109...53,542,431 		JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions
increases expression		 ISO 5,7-Dihydroxytryptamine inhibits the reaction [Cocaine results in increased expression of DUSP8 mRNA] CTD PMID:9813294 NCBI chr 7:142,079,487...142,095,907
Ensembl chr 7:142,079,490...142,095,843 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 affects expression ISO Cocaine affects the expression of DVL1 mRNA CTD PMID:20187946 NCBI chr 4:155,847,402...155,859,303
Ensembl chr 4:155,847,402...155,859,303 		JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Cocaine results in decreased expression of DYNC1I1 mRNA CTD PMID:12629581 NCBI chr 6:5,725,600...6,028,039
Ensembl chr 6:5,725,639...6,028,039 		JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases expression ISO Cocaine results in increased expression of DYNC1LI2 protein CTD PMID:25100957 NCBI chr 8:104,417,674...104,443,050
Ensembl chr 8:104,417,680...104,443,047 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 affects expression ISO Cocaine affects the expression of DYNLL1 mRNA CTD PMID:20187946 NCBI chr 5:115,297,110...115,300,990
Ensembl chr 5:115,297,110...115,300,999 		JBrowse link
G Eci2 enoyl-Coenzyme A delta isomerase 2 affects expression ISO Cocaine affects the expression of PECI mRNA CTD PMID:20187946 NCBI chr13:34,977,748...35,027,115
Ensembl chr13:34,977,748...35,027,096 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Cocaine results in increased expression of EDN1 protein CTD PMID:9714087 PMID:11948058 PMID:17420087 PMID:18813882 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990 		JBrowse link
G Ednra endothelin receptor type A increases expression ISO Cocaine results in increased expression of EDNRA protein CTD PMID:17420087 PMID:18813882 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464 		JBrowse link
G Ednrb endothelin receptor type B affects expression ISO Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 NCBI chr14:103,814,615...103,844,508
Ensembl chr14:103,814,625...103,844,402 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression ISO Cocaine affects the expression of EEF1A1 mRNA CTD PMID:20187946 NCBI chr 9:78,478,453...78,481,724
Ensembl chr 9:78,478,449...78,489,151 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 affects expression ISO Cocaine affects the expression of EEF1A2 mRNA CTD PMID:20187946 NCBI chr 2:181,141,758...181,157,015
Ensembl chr 2:181,147,653...181,157,014 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma decreases expression ISO Cocaine results in decreased expression of EEF1G mRNA CTD PMID:15009677 NCBI chr19:8,967,041...8,978,180
Ensembl chr19:8,967,041...8,978,479 		JBrowse link
G Efcab3 EF-hand calcium binding domain 3 affects expression
decreases expression		 ISO Cocaine affects the expression of EFCAB3 mRNA
Cocaine results in decreased expression of EFCAB3 mRNA		 CTD PMID:17898221 PMID:20187946 NCBI chr11:105,008,985...105,117,537
Ensembl chr11:105,063,592...105,117,537 		JBrowse link
G Efna1 ephrin A1 affects expression ISO Cocaine affects the expression of EFNA1 mRNA CTD PMID:15691709 NCBI chr 3:89,271,730...89,280,951
Ensembl chr 3:89,271,733...89,281,142 		JBrowse link
G Efna2 ephrin A2 affects expression ISO Cocaine affects the expression of EFNA2 mRNA CTD PMID:15691709 NCBI chr10:80,179,482...80,190,010
Ensembl chr10:80,179,482...80,190,010 		JBrowse link
G Efna3 ephrin A3 affects expression ISO Cocaine affects the expression of EFNA3 mRNA CTD PMID:15691709 NCBI chr 3:89,313,899...89,322,939
Ensembl chr 3:89,313,899...89,322,965 		JBrowse link
G Efna4 ephrin A4 affects expression ISO Cocaine affects the expression of EFNA4 mRNA CTD PMID:15691709 NCBI chr 3:89,333,393...89,338,028
Ensembl chr 3:89,333,390...89,338,028 		JBrowse link
G Efna5 ephrin A5 increases expression ISO Cocaine results in increased expression of EFNA5 mRNA CTD PMID:15691709 NCBI chr17:62,602,957...62,881,317
Ensembl chr17:62,604,184...62,881,317 		JBrowse link
G Efnb1 ephrin B1 increases expression ISO Cocaine results in increased expression of EFNB1 mRNA CTD PMID:15691709 PMID:17898221 NCBI chr  X:99,136,061...99,149,022
Ensembl chr  X:99,136,130...99,148,991 		JBrowse link
G Efnb2 ephrin B2 increases expression ISO Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 NCBI chr 8:8,617,235...8,661,242
Ensembl chr 8:8,617,434...8,661,242 		JBrowse link
G Efnb3 ephrin B3 increases expression ISO Cocaine results in increased expression of EFNB3 mRNA CTD PMID:15691709 NCBI chr11:69,554,092...69,561,150
Ensembl chr11:69,554,092...69,560,205 		JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 affects expression ISO Cocaine affects the expression of EFTUD2 mRNA CTD PMID:20187946 NCBI chr11:102,838,472...102,880,984
Ensembl chr11:102,838,473...102,880,985 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158 		JBrowse link
G Egr1 early growth response 1 affects expression
increases expression
multiple interactions
increases response to substance		 EXP
ISO		 Cocaine affects the expression of EGR1 mRNA
Cocaine results in increased expression of EGR1 protein
NPPC protein inhibits the reaction [Cocaine results in increased expression of EGR1 mRNA]
Cocaine results in increased expression of EGR1 mRNA; Cocaine results in increased expression of EGR1 protein
EGR1 results in increased susceptibility to Cocaine
[Cocaine co-treated with Caffeine] results in increased expression of EGR1 mRNA; Cocaine promotes the reaction [Caffeine results in increased expression of EGR1 mRNA]		 CTD PMID:1347779 PMID:7905595 PMID:9890435 PMID:10971643 PMID:11860464 PMID:16339038 PMID:16459018 PMID:16738229 PMID:17851536 PMID:18311559 PMID:18355967 PMID:20187946 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984 		JBrowse link
G Egr2 early growth response 2 increases expression
affects expression		 EXP
ISO		 Cocaine results in increased expression of EGR2 mRNA
Cocaine affects the expression of EGR2 mRNA		 CTD PMID:20056891 PMID:20187946 PMID:27899881 NCBI chr10:67,534,469...67,542,188
Ensembl chr10:67,535,475...67,542,188 		JBrowse link
G Egr3 early growth response 3 affects expression
multiple interactions
increases expression		 ISO Cocaine affects the expression of EGR3 mRNA
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to EGR3 promoter]
Cocaine results in increased expression of EGR3 mRNA		 CTD PMID:16459018 PMID:20187946 PMID:30158054 NCBI chr14:70,077,317...70,082,613
Ensembl chr14:70,077,203...70,082,614 		JBrowse link
G Egr4 early growth response 4 increases expression ISO Cocaine results in increased expression of EGR4 mRNA CTD PMID:27899881 NCBI chr 6:85,511,121...85,513,589
Ensembl chr 6:85,511,121...85,513,589 		JBrowse link
G Ehd2 EH-domain containing 2 decreases expression ISO Cocaine results in decreased expression of EHD2 mRNA CTD PMID:17898221 NCBI chr 7:15,946,963...15,967,535
Ensembl chr 7:15,946,958...15,967,567 		JBrowse link
G Ehmt1 euchromatic histone methyltransferase 1 decreases expression EXP Cocaine results in decreased expression of EHMT1 mRNA CTD PMID:20056891 NCBI chr 2:24,790,769...24,919,643
Ensembl chr 2:24,789,928...24,919,614 		JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 multiple interactions
decreases response to substance
decreases expression		 EXP Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TGFBR1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TNFRSF25 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of USP9X mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of WNK3 mRNA]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]
EHMT2 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of EHMT2 mRNA; Cocaine results in decreased expression of EHMT2 protein		 CTD PMID:20056891 NCBI chr17:34,898,463...34,914,073
Ensembl chr17:34,898,469...34,914,052 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression ISO Cocaine results in increased expression of EIF1A mRNA CTD PMID:17898221 NCBI chr18:46,597,704...46,610,225
Ensembl chr18:46,597,701...46,616,456 		JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked increases expression ISO Cocaine results in increased expression of EIF1AY mRNA CTD PMID:17898221 NCBI chr  X:159,372,178...159,389,621
Ensembl chr  X:159,372,178...159,389,928 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 ISO Cocaine results in increased expression of EIF2AK3 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]		 CTD PMID:17303341 NCBI chr 6:70,844,484...70,905,241
Ensembl chr 6:70,844,515...70,905,245 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation ISO Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 NCBI chr12:78,862,072...78,887,010
Ensembl chr12:78,861,819...78,887,010 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression ISO Cocaine results in increased expression of EIF3A mRNA CTD PMID:17898221 NCBI chr19:60,761,116...60,790,693
Ensembl chr19:60,761,117...60,790,658 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects expression ISO Cocaine affects the expression of EIF3B mRNA CTD PMID:20187946 NCBI chr 5:140,419,305...140,443,358
Ensembl chr 5:140,419,328...140,443,360 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression ISO Cocaine results in increased expression of EIF3C mRNA CTD PMID:17898221 NCBI chr 7:126,546,911...126,566,366
Ensembl chr 7:126,546,455...126,566,411 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3, subunit E affects expression ISO Cocaine affects the expression of EIF3E mRNA CTD PMID:20187946 NCBI chr15:43,250,040...43,282,736
Ensembl chr15:43,250,058...43,282,719 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B multiple interactions
increases expression		 EXP FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA] CTD PMID:18355967 NCBI chr15:102,073,773...102,097,173
Ensembl chr15:102,073,773...102,097,173 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression
affects expression
increases expression		 ISO Cocaine results in decreased expression of EIF5A mRNA
Cocaine affects the expression of EIF5A mRNA
Cocaine results in increased expression of EIF5A mRNA		 CTD PMID:15009677 PMID:16710320 PMID:20187946 NCBI chr11:69,916,712...69,921,958
Ensembl chr11:69,916,714...69,921,958 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression ISO Cocaine results in increased expression of EIF5B mRNA CTD PMID:17898221 NCBI chr 1:37,998,010...38,055,579
Ensembl chr 1:37,998,010...38,055,579 		JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein] CTD PMID:18438818 NCBI chr10:79,886,312...79,888,216
Ensembl chr10:79,886,247...79,888,215 		JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions
increases expression		 EXP EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA] CTD PMID:20056891 NCBI chr13:20,090,507...20,608,353
Ensembl chr13:20,090,596...20,608,353 		JBrowse link
G Emc9 ER membrane protein complex subunit 9 affects expression ISO Cocaine affects the expression of EMC9 mRNA CTD PMID:20187946 NCBI chr14:55,581,519...55,585,375
Ensembl chr14:55,581,516...55,585,302 		JBrowse link
G Enah ENAH actin regulator increases expression ISO Cocaine results in increased expression of ENAH mRNA CTD PMID:17898221 NCBI chr 1:181,896,384...182,027,556
Ensembl chr 1:181,896,384...182,019,990 		JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO Cocaine results in increased expression of ENC1 mRNA CTD PMID:17898221 NCBI chr13:97,241,105...97,253,040
Ensembl chr13:97,241,105...97,253,034 		JBrowse link
G Enho energy homeostasis associated decreases expression ISO Cocaine results in decreased expression of ENHO mRNA CTD PMID:16710320 NCBI chr 4:41,638,144...41,640,302
Ensembl chr 4:41,638,144...41,640,324 		JBrowse link
G Eno2 enolase 2, gamma neuronal decreases expression
increases expression		 ISO Cocaine results in decreased expression of ENO2 mRNA
Cocaine results in increased expression of ENO2 protein		 CTD PMID:12629581 PMID:17075605 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673 		JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase 5 increases expression ISO Cocaine results in increased expression of ENPP5 mRNA CTD PMID:15009677 NCBI chr17:44,078,802...44,086,567
Ensembl chr17:44,078,813...44,086,567 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression ISO Cocaine results in decreased expression of ENTPD2 protein CTD PMID:25100957 NCBI chr 2:25,395,874...25,401,323
Ensembl chr 2:25,395,874...25,401,321 		JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA CTD PMID:18355967 NCBI chr 9:120,539,818...120,568,327
Ensembl chr 9:120,539,818...120,568,327 		JBrowse link
G Epha1 Eph receptor A1 affects expression ISO Cocaine affects the expression of EPHA1 mRNA CTD PMID:15691709 NCBI chr 6:42,358,487...42,373,314
Ensembl chr 6:42,358,487...42,373,268 		JBrowse link
G Epha2 Eph receptor A2 affects expression ISO Cocaine affects the expression of EPHA2 mRNA CTD PMID:15691709 NCBI chr 4:141,301,221...141,329,384
Ensembl chr 4:141,301,240...141,329,384 		JBrowse link
G Epha3 Eph receptor A3 affects expression ISO Cocaine affects the expression of EPHA3 mRNA CTD PMID:15691709 NCBI chr16:63,543,532...63,864,175
Ensembl chr16:63,543,534...63,864,175 		JBrowse link
G Epha4 Eph receptor A4 affects expression
increases expression		 ISO Cocaine affects the expression of EPHA4 mRNA
Cocaine results in increased expression of EPHA4 mRNA		 CTD PMID:15691709 PMID:17898221 NCBI chr 1:77,367,182...77,515,107
Ensembl chr 1:77,367,185...77,515,088 		JBrowse link
G Epha5 Eph receptor A5 affects expression ISO Cocaine affects the expression of EPHA5 mRNA CTD PMID:15691709 NCBI chr 5:84,054,761...84,417,818
Ensembl chr 5:84,054,761...84,417,382 		JBrowse link
G Epha7 Eph receptor A7 affects expression ISO Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 NCBI chr 4:28,813,066...28,967,503
Ensembl chr 4:28,813,131...28,967,499 		JBrowse link
G Epha8 Eph receptor A8 affects expression ISO Cocaine affects the expression of EPHA8 mRNA CTD PMID:15691709 NCBI chr 4:136,929,419...136,956,859
Ensembl chr 4:136,929,419...136,956,816 		JBrowse link
G Ephb1 Eph receptor B1 increases expression EXP
ISO		 Cocaine results in increased expression of EPHB1 protein
Cocaine results in increased expression of EPHB1 mRNA		 CTD PMID:11146119 PMID:15691709 NCBI chr 9:101,922,128...102,354,693
Ensembl chr 9:101,922,128...102,354,693 		JBrowse link
G Ephb2 Eph receptor B2 increases expression ISO Cocaine results in increased expression of EPHB2 mRNA CTD PMID:15691709 NCBI chr 4:136,647,536...136,836,326
Ensembl chr 4:136,647,539...136,835,988 		JBrowse link
G Ephb3 Eph receptor B3 affects expression ISO Cocaine affects the expression of EPHB3 mRNA CTD PMID:15691709 NCBI chr16:21,204,620...21,223,309
Ensembl chr16:21,204,755...21,223,305 		JBrowse link
G Ephb4 Eph receptor B4 decreases expression
affects expression		 ISO Cocaine results in decreased expression of EPHB4 mRNA
Cocaine affects the expression of EPHB4 mRNA		 CTD PMID:15691709 PMID:18000554 NCBI chr 5:137,350,109...137,374,522
Ensembl chr 5:137,350,109...137,378,669 		JBrowse link
G Ephb6 Eph receptor B6 affects expression ISO Cocaine affects the expression of EPHB6 mRNA CTD PMID:15691709 NCBI chr 6:41,603,834...41,620,509
Ensembl chr 6:41,605,482...41,620,509 		JBrowse link
G Erbin Erbb2 interacting protein multiple interactions EXP HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA] CTD PMID:17988634 NCBI chr13:103,818,786...103,920,586
Ensembl chr13:103,818,787...103,920,514 		JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 multiple interactions
increases expression		 ISO 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852 		JBrowse link
G Ess2 ess-2 splicing factor decreases expression ISO Cocaine results in decreased expression of ESS2 mRNA CTD PMID:17898221 NCBI chr16:17,900,709...17,911,348
Ensembl chr16:17,900,709...17,911,348 		JBrowse link
G Etf1 eukaryotic translation termination factor 1 affects expression ISO Cocaine affects the expression of ETF1 mRNA CTD PMID:20187946 NCBI chr18:34,902,785...34,932,008
Ensembl chr18:34,902,785...34,932,007 		JBrowse link
G Etfa electron transferring flavoprotein, alpha polypeptide affects expression ISO Cocaine affects the expression of ETFA mRNA CTD PMID:20187946 NCBI chr 9:55,454,436...55,512,243
Ensembl chr 9:55,454,508...55,512,243 		JBrowse link
G Exoc2 exocyst complex component 2 increases expression ISO Cocaine results in increased expression of EXOC2 protein CTD PMID:25100957 NCBI chr13:30,789,516...30,974,096
Ensembl chr13:30,813,919...30,974,093 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 increases expression ISO Cocaine results in increased expression of EYA1 mRNA CTD PMID:15009677 NCBI chr 1:14,168,953...14,311,035
Ensembl chr 1:14,168,954...14,310,235 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 affects expression ISO Cocaine affects the expression of EYA2 mRNA CTD PMID:20187946 NCBI chr 2:165,595,028...165,771,727
Ensembl chr 2:165,595,032...165,771,727 		JBrowse link
G Ezr ezrin decreases expression ISO Cocaine results in decreased expression of EZR mRNA CTD PMID:20948987 NCBI chr17:6,738,131...6,782,780
Ensembl chr17:6,738,041...6,782,784 		JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain affects expression
multiple interactions
decreases expression		 ISO Cocaine affects the expression of FADD mRNA
Raclopride affects the reaction [Cocaine affects the expression of FADD protein]
Cocaine results in decreased expression of FADD protein modified form		 CTD PMID:18580876 NCBI chr 7:144,578,323...144,582,441
Ensembl chr 7:144,577,318...144,582,463 		JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 increases expression ISO Cocaine results in increased expression of FAHD1 protein CTD PMID:25100957 NCBI chr17:24,848,896...24,850,302
Ensembl chr17:24,848,892...24,850,364 		JBrowse link
G Fahd2a fumarylacetoacetate hydrolase domain containing 2A affects expression ISO Cocaine affects the expression of FAHD2A protein CTD PMID:19393250 NCBI chr 2:127,436,215...127,444,571
Ensembl chr 2:127,436,215...127,444,565 		JBrowse link
G Faim Fas apoptotic inhibitory molecule affects expression EXP Cocaine affects the expression of FAIM mRNA CTD PMID:15681117 NCBI chr 9:98,986,373...99,002,019
Ensembl chr 9:98,986,373...99,002,021 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO Cocaine results in increased expression of FAIM2 mRNA CTD PMID:16076954 NCBI chr15:99,497,005...99,534,880
Ensembl chr15:99,497,012...99,528,165 		JBrowse link
G Fam155a family with sequence similarity 155, member A increases expression ISO Cocaine results in increased expression of FAM155A mRNA CTD PMID:17898221 NCBI chr 8:9,206,006...9,773,329
Ensembl chr 8:9,205,902...9,771,161 		JBrowse link
G Fam184b family with sequence similarity 184, member B decreases expression ISO Cocaine results in decreased expression of FAM184B mRNA CTD PMID:27899881 NCBI chr 5:45,529,705...45,639,501
Ensembl chr 5:45,529,705...45,639,614 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression ISO Cocaine affects the expression of FAM20C mRNA CTD PMID:20187946 NCBI chr 5:138,755,081...138,810,063
Ensembl chr 5:138,754,514...138,810,077 		JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression ISO Cocaine results in decreased expression of FAM78B mRNA CTD PMID:17898221 NCBI chr 1:166,999,851...167,091,302
Ensembl chr 1:167,001,417...167,091,302 		JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression ISO Cocaine results in increased expression of FAS mRNA CTD PMID:16710320 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772 		JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression ISO Cocaine results in increased expression of FBXL3 mRNA CTD PMID:17898221 NCBI chr14:103,080,239...103,099,566
Ensembl chr14:103,080,239...103,099,566 		JBrowse link
G Fbxo46 F-box protein 46 affects expression ISO Cocaine affects the expression of FBXO46 mRNA CTD PMID:20187946 NCBI chr 7:19,119,859...19,138,261
Ensembl chr 7:19,119,859...19,140,172 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb decreases expression ISO Cocaine results in decreased expression of FCGR2B mRNA CTD PMID:27899881 NCBI chr 1:170,960,558...170,976,071
Ensembl chr 1:170,958,617...170,976,547 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr14:63,145,150...63,181,687
Ensembl chr14:63,145,150...63,179,578 		JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression ISO Cocaine results in decreased expression of FEV mRNA CTD PMID:17898221 NCBI chr 1:74,881,501...74,885,473
Ensembl chr 1:74,881,509...74,885,419 		JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression ISO Cocaine results in increased expression of FGD5 mRNA CTD PMID:17898221 NCBI chr 6:91,978,827...92,076,005
Ensembl chr 6:91,978,878...92,076,004 		JBrowse link
G Fgf12 fibroblast growth factor 12 affects expression ISO Cocaine affects the expression of FGF12 mRNA CTD PMID:20187946 NCBI chr16:28,157,783...28,753,243
Ensembl chr16:28,160,098...28,753,068 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Cocaine results in decreased expression of FGF2 mRNA CTD PMID:12629581 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 increases expression ISO Cocaine results in increased expression of FGFR1 mRNA CTD PMID:16076954 NCBI chr 8:25,518,759...25,575,718
Ensembl chr 8:25,513,654...25,575,718 		JBrowse link
G Fh1 fumarate hydratase 1 affects expression ISO Cocaine affects the expression of FH1 protein CTD PMID:19393250 NCBI chr 1:175,601,378...175,625,635
Ensembl chr 1:175,600,374...175,625,635 		JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Cocaine results in increased expression of FIS1 mRNA CTD PMID:31494168 NCBI chr 5:136,953,275...136,966,234
Ensembl chr 5:136,953,275...136,966,234 		JBrowse link
G Fkbp1b FK506 binding protein 1b affects expression ISO Cocaine affects the expression of FKBP1B mRNA CTD PMID:20187946 NCBI chr12:4,833,176...4,841,573
Ensembl chr12:4,833,174...4,841,591 		JBrowse link
G Fkbpl FK506 binding protein-like affects expression ISO Cocaine affects the expression of FKBPL mRNA CTD PMID:20187946 NCBI chr17:34,644,814...34,646,817
Ensembl chr17:34,644,764...34,646,324 		JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 increases expression ISO Cocaine results in increased expression of FLRT3 mRNA CTD PMID:18000554 NCBI chr 2:140,658,198...140,671,476
Ensembl chr 2:140,650,914...140,671,469 		JBrowse link
G Flywch1 FLYWCH-type zinc finger 1 decreases expression ISO Cocaine results in decreased expression of FLYWCH1 mRNA CTD PMID:17898221 NCBI chr17:23,752,795...23,774,530
Ensembl chr17:23,752,793...23,771,602 		JBrowse link
G Fmr1 FMRP translational regulator 1 decreases expression ISO Cocaine results in decreased expression of FMR1 mRNA CTD PMID:24810662 NCBI chr  X:68,678,536...68,717,963
Ensembl chr  X:68,678,541...68,717,963 		JBrowse link
G Fndc1 fibronectin type III domain containing 1 multiple interactions EXP [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA CTD PMID:18355967 NCBI chr17:7,738,569...7,827,340
Ensembl chr17:7,738,569...7,827,302 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression ISO Cocaine affects the expression of FNDC5 mRNA CTD PMID:20187946 NCBI chr 4:129,136,870...129,144,593
Ensembl chr 4:129,136,999...129,144,593 		JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
affects expression
increases phosphorylation
decreases response to substance
increases activity
decreases expression		 ISO
EXP		 [Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]
Cocaine results in increased expression of FOS mRNA; Cocaine results in increased expression of FOS protein
Cocaine affects the expression of FOS mRNA; Cocaine affects the expression of FOS protein
Cocaine results in increased phosphorylation of FOS protein
[Morphine co-treated with Cocaine] affects the expression of FOS; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Alcohols promotes the reaction [Cocaine results in increased expression of FOS protein]; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; Chloral Hydrate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Cocaine promotes the reaction [Cocaine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [Ethanol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; ecopipam inhibits the reaction [Cocaine results in increased expression of FOS protein]; Ethanol promotes the reaction [Cocaine results in increased expression of FOS protein]; Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; Urethane inhibits the reaction [Cocaine results in increased expression of FOS protein]; volinanserin inhibits the reaction [Cocaine results in increased expression of FOS protein]
FOS protein mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased activity of FOS protein
Cocaine results in decreased expression of FOS protein
[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of PDYN protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of SYT7 protein; [Cocaine co-treated with Caffeine] results in increased expression of FOS mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of NEXN mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PBX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PER1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PINX1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PKNOX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PLPP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PRKCZ mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SYT9 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of THRA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of LARGE1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of NRIP3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SATB2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SORCS3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of TENM4 mRNA; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [Caffeine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of MAPK11 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NCALD mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NPTXR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NRN1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of PRKCA mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SATB1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SEZ6L mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KCNT1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LIN7B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of MEPCE mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NIT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NOS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PBX3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PPP1R7 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PRPF18 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PTPRV mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SBSN mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYNE1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of TSPOAP1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ZFPM1 mRNA]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOS protein]; N-methyl-3-(bis(4'-fluorophenyl)methoxy)tropane inhibits the reaction [Cocaine results in increased expression of FOS protein]; NTRK2 protein affects the reaction [Cocaine affects the expression of FOS protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in increased expression of FOS protein]; RPS6KA3 affects the reaction [Cocaine results in increased phosphorylation of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased activity of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS protein]		 CTD PMID:1498673 PMID:2118661 PMID:7905595 PMID:10415707 PMID:10521585 PMID:10632609 PMID:10814832 PMID:10904129 PMID:10943692 PMID:10971643 PMID:11160452 PMID:11172061 PMID:11403691 PMID:11421588 PMID:11716816 PMID:11739600 PMID:11860464 PMID:11882344 PMID:12112414 PMID:12122080 PMID:12128156 PMID:12379259 PMID:12419516 PMID:12581847 PMID:12670717 PMID:12699766 PMID:12786985 PMID:12821175 PMID:14644470 PMID:14741756 PMID:15056714 PMID:15219685 PMID:15254092 PMID:15295023 PMID:15665076 PMID:15814102 PMID:16179556 PMID:16263220 PMID:16300424 PMID:16339038 PMID:16395306 PMID:16459018 PMID:16710312 PMID:16930414 PMID:16962079 PMID:17276011 PMID:17596442 PMID:17851536 PMID:18164822 PMID:18311559 PMID:18355967 PMID:18396266 PMID:18479823 PMID:18822274 PMID:18991842 PMID:19169671 PMID:19606084 PMID:19620976 PMID:20187946 PMID:20633205 PMID:20947769 PMID:25933444 PMID:27899881 PMID:31059705 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273 		JBrowse link
G Fosb FBJ osteosarcoma oncogene B increases expression
multiple interactions
affects expression		 ISO
EXP		 Cocaine results in increased expression of FOSB protein
DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
Cocaine results in increased expression of FOSB mRNA; Cocaine results in increased expression of FOSB protein; Cocaine results in increased expression of FOSB protein alternative form
Cocaine affects the expression of FOSB mRNA; Cocaine affects the expression of FOSB protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein; [JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine; Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; PPP1R1B gene mutant form inhibits the reaction [Cocaine results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]		 CTD PMID:10103106 PMID:11391778 PMID:11739600 PMID:12417638 PMID:15056714 PMID:15814102 PMID:15926929 PMID:16263220 PMID:16674926 PMID:16710312 PMID:17898221 PMID:18293355 PMID:18355967 PMID:18822274 PMID:20056891 PMID:20633205 PMID:27899881 NCBI chr 7:19,302,696...19,310,118
Ensembl chr 7:19,302,696...19,310,051 		JBrowse link
G Fosl1 fos-like antigen 1 affects expression
decreases expression		 ISO Cocaine affects the expression of FOSL1 mRNA
Cocaine results in decreased expression of FOSL1 mRNA		 CTD PMID:12117546 PMID:12629581 NCBI chr19:5,447,698...5,455,938
Ensembl chr19:5,447,547...5,455,946 		JBrowse link
G Fosl2 fos-like antigen 2 multiple interactions
decreases expression		 ISO
EXP		 Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein]
Cocaine results in decreased expression of FOSL2 protein		 CTD PMID:15056714 PMID:15814102 NCBI chr 5:32,136,472...32,157,840
Ensembl chr 5:32,135,801...32,157,842 		JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Cocaine results in decreased expression of FOXC2 mRNA CTD PMID:17898221 NCBI chr 8:121,116,171...121,118,895
Ensembl chr 8:121,116,171...121,118,895 		JBrowse link
G Foxo1 forkhead box O1 decreases expression ISO Cocaine results in decreased expression of FOXO1 mRNA CTD PMID:17898221 NCBI chr 3:52,268,337...52,350,109
Ensembl chr 3:52,268,336...52,353,221 		JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression ISO Cocaine results in increased expression of FRAS1 mRNA CTD PMID:17898221 NCBI chr 5:96,373,777...96,784,733
Ensembl chr 5:96,373,955...96,784,728 		JBrowse link
G Frem2 Fras1 related extracellular matrix protein 2 decreases expression ISO Cocaine results in decreased expression of FREM2 mRNA CTD PMID:27899881 NCBI chr 3:53,513,938...53,658,593
Ensembl chr 3:53,513,938...53,657,355 		JBrowse link
G Frmd5 FERM domain containing 5 decreases expression ISO Cocaine results in decreased expression of FRMD5 mRNA CTD PMID:17898221 NCBI chr 2:121,545,529...121,807,087
Ensembl chr 2:121,545,529...121,807,087 		JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression ISO Cocaine affects the expression of FRS3 mRNA CTD PMID:20187946 NCBI chr17:47,687,607...47,704,286
Ensembl chr17:47,689,030...47,704,286 		JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 affects expression ISO Cocaine affects the expression of FUBP1 mRNA CTD PMID:20187946 NCBI chr 3:152,210,422...152,236,830
Ensembl chr 3:152,210,422...152,236,826 		JBrowse link
G Fut8 fucosyltransferase 8 affects expression ISO Cocaine affects the expression of FUT8 mRNA CTD PMID:20187946 NCBI chr12:77,237,430...77,475,998
Ensembl chr12:77,238,125...77,476,338 		JBrowse link
G Fzd6 frizzled class receptor 6 affects expression ISO Cocaine affects the expression of FZD6 mRNA CTD PMID:20187946 NCBI chr15:39,006,149...39,038,192
Ensembl chr15:39,006,034...39,038,188 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases expression ISO Cocaine results in increased expression of G6PD protein CTD PMID:25100957 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194 		JBrowse link
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor, 1 affects expression
increases expression
decreases expression		 ISO Cocaine affects the expression of GABBR1 mRNA
Cocaine results in increased expression of GABBR1 mRNA
Cocaine results in decreased expression of GABBR1 mRNA		 CTD PMID:11793422 PMID:16076954 PMID:20187946 NCBI chr17:37,045,966...37,074,305
Ensembl chr17:37,045,966...37,075,067 		JBrowse link
G Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 decreases phosphorylation ISO Cocaine results in decreased phosphorylation of GABBR2 protein CTD PMID:12716959 NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873 		JBrowse link
G Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 affects expression
multiple interactions		 ISO Cocaine affects the expression of GABRA1 protein
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]		 CTD PMID:20826313 PMID:23266428 PMID:32209479 NCBI chr11:42,130,939...42,183,066
Ensembl chr11:42,130,939...42,182,930 		JBrowse link
G Gabrb1 gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 increases expression ISO Cocaine results in increased expression of GABRB1 mRNA CTD PMID:17898221 NCBI chr 5:71,657,921...72,149,572
Ensembl chr 5:71,658,113...72,149,037 		JBrowse link
G Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 multiple interactions ISO 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]		 CTD PMID:23266428 PMID:32209479 NCBI chr11:42,419,515...42,632,591
Ensembl chr11:42,419,757...42,629,028 		JBrowse link
G Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 affects expression
multiple interactions		 ISO Cocaine affects the expression of GABRB3 mRNA
Cocaine affects the phosphorylation of and affects the expression of GABRB3 protein		 CTD PMID:20187946 PMID:20826313 NCBI chr 7:57,590,518...57,828,802
Ensembl chr 7:57,419,692...57,828,802 		JBrowse link
G Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 multiple interactions ISO 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]		 CTD PMID:23266428 PMID:32209479 NCBI chr11:41,910,190...42,000,857
Ensembl chr11:41,910,203...42,000,857 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression
increases expression		 ISO Cocaine results in decreased expression of GAD1 mRNA
Cocaine results in increased expression of GAD1 protein		 CTD PMID:12629581 PMID:15295023 PMID:18611417 NCBI chr 2:70,561,303...70,602,014
Ensembl chr 2:70,553,072...70,602,014 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:19099295 NCBI chr19:3,409,915...3,414,544
Ensembl chr19:3,409,915...3,414,544 		JBrowse link
G Galk1 galactokinase 1 affects expression ISO Cocaine affects the expression of GALK1 mRNA CTD PMID:20187946 NCBI chr11:116,008,357...116,012,719
Ensembl chr11:116,008,457...116,012,719 		JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression ISO Cocaine results in increased expression of GALNT1 mRNA CTD PMID:17898221 NCBI chr18:24,205,321...24,286,816
Ensembl chr18:24,205,344...24,286,818 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 affects expression ISO Cocaine affects the expression of GALNT16 mRNA CTD PMID:20187946 NCBI chr12:80,518,471...80,603,898
Ensembl chr12:80,518,277...80,630,972 		JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Cocaine results in decreased expression of GAP43 mRNA CTD PMID:12629581 NCBI chr16:42,248,552...42,340,651
Ensembl chr16:42,248,442...42,340,651 		JBrowse link
G Gas2 growth arrest specific 2 affects expression EXP Cocaine affects the expression of GAS2 mRNA CTD PMID:15681117 NCBI chr 7:51,861,791...51,995,005
Ensembl chr 7:51,862,015...51,994,975 		JBrowse link
G Gcc1 golgi coiled coil 1 increases expression ISO Cocaine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 6:28,416,603...28,421,724
Ensembl chr 6:28,416,091...28,428,390 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions		 EXP Cocaine results in increased expression of GCLC mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]		 CTD PMID:30393195 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit affects expression
increases expression
multiple interactions		 ISO
EXP		 Cocaine affects the expression of GCLM mRNA
Cocaine results in increased expression of GCLM mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]		 CTD PMID:20187946 PMID:30393195 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732 		JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 increases expression ISO Cocaine results in increased expression of GDAP1 protein CTD PMID:25100957 NCBI chr 1:17,145,373...17,164,271
Ensembl chr 1:17,145,362...17,164,271 		JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression ISO Cocaine results in decreased expression of GDAP1L1 protein CTD PMID:25100957 NCBI chr 2:163,438,420...163,455,324
Ensembl chr 2:163,438,476...163,455,324 		JBrowse link
G Gdnf glial cell line derived neurotrophic factor decreases expression ISO Cocaine results in decreased expression of GDNF mRNA CTD PMID:14622243 NCBI chr15:7,810,048...7,837,580
Ensembl chr15:7,810,846...7,837,575 		JBrowse link
G Gem GTP binding protein (gene overexpressed in skeletal muscle) increases expression ISO Cocaine results in increased expression of GEM mRNA CTD PMID:15009677 NCBI chr 4:11,704,447...11,714,993
Ensembl chr 4:11,704,457...11,714,752 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
affects expression		 ISO
EXP		 Cocaine results in increased expression of GFAP protein
Cocaine results in decreased expression of GFAP protein
Cocaine affects the expression of GFAP mRNA; Cocaine affects the expression of GFAP protein		 CTD PMID:11391778 PMID:11882367 PMID:12670315 PMID:15814102 PMID:20187946 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912 		JBrowse link
G Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 affects expression ISO Cocaine affects the expression of GFRA2 mRNA CTD PMID:12358776 NCBI chr14:70,890,107...70,979,840
Ensembl chr14:70,890,120...70,979,838 		JBrowse link
G Gh growth hormone multiple interactions ISO Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein]; Cocaine inhibits the reaction [Sodium Oxybate results in increased expression of GH1 protein]		 CTD PMID:9413023 PMID:10657535 PMID:15099682 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865 		JBrowse link
G Gid8 GID complex subunit 8 affects expression ISO Cocaine affects the expression of GID8 mRNA CTD PMID:20187946 NCBI chr 2:180,710,122...180,721,599
Ensembl chr 2:180,710,117...180,718,733 		JBrowse link
G Gimap1 GTPase, IMAP family member 1 affects expression ISO Cocaine affects the expression of GIMAP1 mRNA CTD PMID:20187946 NCBI chr 6:48,739,047...48,743,795
Ensembl chr 6:48,739,054...48,743,795 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 affects expression ISO Cocaine affects the expression of GIMAP5 mRNA CTD PMID:20187946 NCBI chr 6:48,746,197...48,754,200
Ensembl chr 6:48,746,197...48,754,210 		JBrowse link
G Gins3 GINS complex subunit 3 (Psf3 homolog) decreases expression ISO Cocaine results in decreased expression of GINS3 mRNA CTD PMID:27899881 NCBI chr 8:95,633,559...95,645,059
Ensembl chr 8:95,633,453...95,645,060 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects expression ISO Cocaine affects the expression of GIPC1 mRNA CTD PMID:20187946 NCBI chr 8:83,649,408...83,664,789
Ensembl chr 8:83,652,677...83,664,694 		JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression ISO Cocaine results in increased expression of GJA5 mRNA CTD PMID:27899881 NCBI chr 3:97,032,402...97,053,634
Ensembl chr 3:96,904,693...97,077,416 		JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression ISO Cocaine affects the expression of GJB1 mRNA; Cocaine affects the expression of GJB1 protein CTD PMID:10510198 NCBI chr  X:101,376,376...101,385,629
Ensembl chr  X:101,376,378...101,385,629 		JBrowse link
G Gjb2 gap junction protein, beta 2 decreases expression ISO Cocaine results in decreased expression of GJB2 mRNA CTD PMID:12629581 NCBI chr14:57,098,602...57,104,702
Ensembl chr14:57,098,600...57,104,702 		JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression ISO Cocaine results in decreased expression of GJB5 mRNA CTD PMID:27899881 NCBI chr 4:127,354,809...127,358,164
Ensembl chr 4:127,354,809...127,358,181 		JBrowse link
G Gjd2 gap junction protein, delta 2 affects expression ISO Cocaine affects the expression of GJD2 mRNA; Cocaine affects the expression of GJD2 protein CTD PMID:16138316 NCBI chr 2:114,009,601...114,014,378
Ensembl chr 2:114,009,601...114,013,619 		JBrowse link
G Gli2 GLI-Kruppel family member GLI2 decreases expression ISO Cocaine results in decreased expression of GLI2 mRNA CTD PMID:27899881 NCBI chr 1:118,834,061...119,054,405
Ensembl chr 1:118,834,132...119,053,619 		JBrowse link
G Glp2r glucagon-like peptide 2 receptor decreases expression ISO Cocaine results in decreased expression of GLP2R mRNA CTD PMID:17898221 NCBI chr11:67,664,156...67,771,184
Ensembl chr11:67,661,502...67,771,153 		JBrowse link
G Glra1 glycine receptor, alpha 1 subunit multiple interactions ISO Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]; Dronabinol inhibits the reaction [Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]] CTD PMID:32209479 NCBI chr11:55,514,239...55,608,198
Ensembl chr11:55,514,238...55,608,198 		JBrowse link
G Glrx3 glutaredoxin 3 affects expression ISO Cocaine affects the expression of GLRX3 mRNA CTD PMID:20187946 NCBI chr 7:137,437,573...137,469,631
Ensembl chr 7:137,437,614...137,468,594 		JBrowse link
G Gm13889 predicted gene 13889 increases expression ISO Cocaine results in increased expression of RGD1564664 mRNA CTD PMID:27899881 NCBI chr 2:93,955,810...93,957,100
Ensembl chr 2:93,955,810...93,957,201 		JBrowse link
G Gm38521 predicted gene, 38521 decreases expression ISO Cocaine results in decreased expression of CCDC73 mRNA CTD PMID:17898221 NCBI chr 2:105,017,121...105,020,725 JBrowse link
G Gm6614 predicted gene 6614 affects expression ISO Cocaine affects the expression of SLCO1A3 mRNA CTD PMID:20187946 NCBI chr 6:141,971,833...142,012,263
Ensembl chr 6:141,971,845...142,011,414 		JBrowse link
G Gnao1 guanine nucleotide binding protein, alpha O decreases expression
multiple interactions		 ISO Cocaine results in decreased expression of GNAO1 mRNA
[Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of GNAO1 protein alternative form		 CTD PMID:12629581 PMID:19457111 NCBI chr 8:93,810,153...93,969,388
Ensembl chr 8:93,809,966...93,969,388 		JBrowse link
G Gnat1 guanine nucleotide binding protein, alpha transducing 1 increases expression ISO Cocaine results in increased expression of GNAT1 mRNA CTD PMID:27899881 NCBI chr 9:107,674,437...107,679,634
Ensembl chr 9:107,674,474...107,679,712 		JBrowse link
G Gnb1 guanine nucleotide binding protein (G protein), beta 1 decreases expression
increases expression		 ISO Cocaine results in decreased expression of GNB1 mRNA
Cocaine results in increased expression of GNB1 mRNA		 CTD PMID:12629581 PMID:16076954 NCBI chr 4:155,491,300...155,559,269
Ensembl chr 4:155,491,361...155,559,269 		JBrowse link
G Gnb2 guanine nucleotide binding protein (G protein), beta 2 affects expression ISO Cocaine affects the expression of GNB2 mRNA CTD PMID:20187946 NCBI chr 5:137,528,127...137,533,449
Ensembl chr 5:137,528,127...137,533,510 		JBrowse link
G Gnb4 guanine nucleotide binding protein (G protein), beta 4 multiple interactions EXP HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA] CTD PMID:17988634 NCBI chr 3:32,578,587...32,616,673
Ensembl chr 3:32,580,332...32,616,585 		JBrowse link
G Gng12 guanine nucleotide binding protein (G protein), gamma 12 affects expression ISO Cocaine affects the expression of GNG12 mRNA CTD PMID:20187946 NCBI chr 6:66,896,397...67,021,361
Ensembl chr 6:66,896,397...67,021,350 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression
multiple interactions		 EXP Cocaine results in decreased expression of GNRH1 protein
GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]		 CTD PMID:31059705 NCBI chr14:67,745,181...67,749,440
Ensembl chr14:67,745,181...67,749,439 		JBrowse link
G Gp2 glycoprotein 2 (zymogen granule membrane) affects expression ISO Cocaine affects the expression of GP2 mRNA CTD PMID:20187946 NCBI chr 7:119,442,537...119,459,272
Ensembl chr 7:119,442,537...119,459,285 		JBrowse link
G Gpc5 glypican 5 increases expression
multiple interactions		 EXP Cocaine results in increased expression of GPC5 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]		 CTD PMID:18355967 NCBI chr14:115,092,201...116,525,192
Ensembl chr14:115,092,215...116,525,179 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression ISO Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 NCBI chr 5:139,423,150...139,427,800
Ensembl chr 5:139,423,151...139,427,800 		JBrowse link
G Gphn gephyrin increases phosphorylation
multiple interactions		 ISO Cocaine results in increased phosphorylation of GPHN protein
Win 55212-2 promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein]		 CTD PMID:32312805 NCBI chr12:78,217,325...78,684,772
Ensembl chr12:78,226,379...78,684,772 		JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO Cocaine results in decreased expression of GPM6A mRNA CTD PMID:12629581 NCBI chr 8:54,779,434...55,060,878
Ensembl chr 8:54,954,843...55,060,871 		JBrowse link
G Gpm6b glycoprotein m6b decreases expression ISO Cocaine results in decreased expression of GPM6B mRNA CTD PMID:12629581 NCBI chr  X:166,238,943...166,389,033
Ensembl chr  X:166,238,911...166,388,988 		JBrowse link
G Gpr157 G protein-coupled receptor 157 decreases expression ISO Cocaine results in decreased expression of GPR157 mRNA CTD PMID:27899881 NCBI chr 4:150,087,503...150,105,927
Ensembl chr 4:150,087,365...150,105,927 		JBrowse link
G Gpr3 G-protein coupled receptor 3 increases expression ISO Cocaine results in increased expression of GPR3 mRNA CTD PMID:27899881 NCBI chr 4:133,209,340...133,212,536
Ensembl chr 4:133,209,340...133,212,536 		JBrowse link
G Gpr88 G-protein coupled receptor 88 affects expression ISO Cocaine affects the expression of GPR88 mRNA CTD PMID:20187946 NCBI chr 3:116,249,654...116,253,540
Ensembl chr 3:116,249,654...116,253,503 		JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 affects expression ISO Cocaine affects the expression of GPRASP1 mRNA CTD PMID:20187946 NCBI chr  X:135,742,692...135,803,468
Ensembl chr  X:135,742,733...135,803,474 		JBrowse link
G Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) affects expression ISO Cocaine affects the expression of GPSM1 protein CTD PMID:15091342 NCBI chr 2:26,314,611...26,348,237
Ensembl chr 2:26,315,515...26,348,237 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions
increases activity		 EXP PRKCD protein affects the reaction [Cocaine results in increased activity of GPT protein]; rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein] CTD PMID:30393195 NCBI chr15:76,696,726...76,699,675
Ensembl chr15:76,695,716...76,699,686 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
affects response to substance		 EXP GPX1 protein affects the susceptibility to [Cocaine co-treated with prolinedithiocarbamate]; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; prolinedithiocarbamate promotes the reaction [Cocaine results in increased expression of GPX1 protein]
GPX1 protein affects the susceptibility to Cocaine		 CTD PMID:31059705 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343 		JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression ISO Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 NCBI chr11:115,644,045...115,708,597
Ensembl chr11:115,644,045...115,708,597 		JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
increases response to substance
increases expression
decreases phosphorylation
multiple interactions
affects expression		 EXP
ISO		 GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of GRIA1 mRNA; Cocaine results in decreased expression of GRIA1 protein
Cocaine results in increased phosphorylation of GRIA1 protein
GRIA1 protein affects the susceptibility to Cocaine
GRIA1 protein results in increased susceptibility to Cocaine
GRIA1 protein mutant form results in decreased susceptibility to Cocaine; GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of GRIA1 mRNA; Cocaine results in increased expression of GRIA1 protein
Cocaine results in decreased phosphorylation of GRIA1 protein
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIA1 protein; Cocaine results in increased phosphorylation of and results in increased transport of GRIA1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; roscovitine inhibits the reaction [Cocaine results in decreased phosphorylation of GRIA1 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]
Cocaine affects the expression of GRIA1 mRNA; Cocaine affects the expression of GRIA1 protein
Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein]; resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]		 CTD PMID:9886066 PMID:11268215 PMID:11801363 PMID:12511956 PMID:12787079 PMID:14684464 PMID:15140200 PMID:16473939 PMID:16794574 PMID:17680995 PMID:17898221 PMID:18278040 PMID:18430032 PMID:18701074<