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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tropane alkaloid
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Accession:CHEBI:37332 term browser browse the term
Synonyms:related_synonym: tropane alkaloids
 alt_id: CHEBI:27154;   CHEBI:27155


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(S)-atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Hyoscyamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
Anatoxin a term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO anatoxin a inhibits the reaction [iodo-alpha-bungarotoxin binds to CHRNA7 protein] CTD PMID:19448648 NCBI chr15:32,030,462...32,173,018
Ensembl chr15:31,923,438...32,173,018
JBrowse link
atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
EXP Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 2:168,915,468...169,031,396
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions EXP [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 9:130,713,881...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions EXP
ISO
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 PMID:21787676 PMID:22783142 PMID:23047022 PMID:24881594 PMID:26751814 PMID:31794810 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ADCY5 adenylate cyclase 5 increases response to substance ISO ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
JBrowse link
G AQP5 aquaporin 5 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr12:49,961,855...49,965,682
Ensembl chr12:49,961,872...49,965,682
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member multiple interactions EXP Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053
JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO
EXP
[Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX
CTD PMID:17963125 PMID:22981459 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BDKRB2 bradykinin receptor B2 multiple interactions ISO BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BMP6 bone morphogenetic protein 6 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E multiple interactions ISO Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr 1:181,317,712...181,808,084
Ensembl chr 1:181,317,690...181,808,084
JBrowse link
G CALCA calcitonin related polypeptide alpha affects activity ISO Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,354
Ensembl chr11:14,966,668...14,972,354
JBrowse link
G CASP3 caspase 3 increases expression ISO Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCNA1 cyclin A1 increases expression
multiple interactions
EXP Atropine results in increased expression of CCNA1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
CTD PMID:17390078 NCBI chr13:36,430,488...36,442,870
Ensembl chr13:36,431,520...36,442,870
JBrowse link
G CCND3 cyclin D3 multiple interactions EXP [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCNE1 cyclin E1 increases expression
multiple interactions
EXP Atropine results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA
CTD PMID:17390078 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CCNE2 cyclin E2 multiple interactions
increases expression
EXP [Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Atropine results in increased expression of CCNE2 mRNA
CTD PMID:17390078 NCBI chr 8:94,880,224...94,896,671
Ensembl chr 8:94,879,770...94,896,678
JBrowse link
G CD40 CD40 molecule multiple interactions EXP Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CDC20 cell division cycle 20 multiple interactions
increases expression
EXP [Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Atropine results in increased expression of CDC20 mRNA
CTD PMID:17390078 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
JBrowse link
G CDC6 cell division cycle 6 multiple interactions EXP [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr17:40,287,878...40,304,657
Ensembl chr17:40,287,879...40,304,657
JBrowse link
G CDK1 cyclin dependent kinase 1 multiple interactions
increases expression
EXP [Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Atropine results in increased expression of CDK1 mRNA
CTD PMID:17390078 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CES1 carboxylesterase 1 multiple interactions EXP Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr16:55,802,851...55,833,127
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 multiple interactions
decreases activity
ISO
EXP
Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]
CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr11:62,908,675...62,921,861
Ensembl chr11:62,908,679...62,921,807
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions EXP Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,669...137,020,255
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 multiple interactions
decreases activity
EXP Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein
CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr 1:239,386,565...239,915,450
Ensembl chr 1:239,386,565...239,915,452
JBrowse link
G CHRM4 cholinergic receptor muscarinic 4 multiple interactions
affects binding
EXP [WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] CTD PMID:16709648 NCBI chr11:46,383,789...46,391,776
Ensembl chr11:46,385,098...46,386,608
JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 multiple interactions EXP Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr15:33,968,497...34,067,458
Ensembl chr15:33,968,497...34,067,458
Ensembl chr15:33,968,497...34,067,458
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions
affects binding
EXP
ISO
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:15733544 PMID:21791372 NCBI chr20:63,343,223...63,375,471
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
EXP
ISO
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRH corticotropin releasing hormone multiple interactions ISO
EXP
Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
[Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein
CTD PMID:12039681 PMID:12906840 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G DVL2 dishevelled segment polarity protein 2 multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr17:7,225,341...7,234,544
Ensembl chr17:7,225,342...7,234,517
JBrowse link
G EDN1 endothelin 1 multiple interactions EXP EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EGR2 early growth response 2 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,919,900
JBrowse link
G EZR ezrin multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr 6:158,765,744...158,819,368
Ensembl chr 6:158,765,741...158,819,368
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F2R coagulation factor II thrombin receptor multiple interactions ISO [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Atropine results in increased expression of FOS protein
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G GHRL ghrelin and obestatin prepropeptide multiple interactions ISO Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
JBrowse link
G GLRA1 glycine receptor alpha 1 multiple interactions EXP Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr 5:151,822,513...151,924,851
Ensembl chr 5:151,822,513...151,924,842
Ensembl chr 5:151,822,513...151,924,842
JBrowse link
G GRM4 glutamate metabotropic receptor 4 multiple interactions EXP Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 6:34,018,643...34,155,622
Ensembl chr 6:34,018,643...34,155,622
Ensembl chr 6:34,018,643...34,155,622
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions ISO [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 multiple interactions EXP Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,918...54,740,715
JBrowse link
G LTF lactotransferrin multiple interactions EXP Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr10:48,306,673...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MCM4 minichromosome maintenance complex component 4 multiple interactions
increases expression
EXP [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA
CTD PMID:17390078 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160
JBrowse link
G MCM6 minichromosome maintenance complex component 6 increases expression
multiple interactions
EXP Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA
CTD PMID:17390078 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443
JBrowse link
G NEFH neurofilament heavy affects expression ISO Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 increases expression EXP Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr 1:247,416,163...247,448,823
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOTCH4 notch receptor 4 multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067
JBrowse link
G NPPA natriuretic peptide A affects activity ISO Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr20:64,080,082...64,100,643
Ensembl chr20:64,080,082...64,100,643
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions EXP Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PNOC prepronociceptin multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 8:28,316,979...28,343,355
Ensembl chr 8:28,316,986...28,343,355
JBrowse link
G POMC proopiomelanocortin multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216
JBrowse link
G PXN paxillin multiple interactions EXP Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr12:120,210,447...120,265,737
Ensembl chr12:120,210,439...120,265,771
JBrowse link
G RAC3 Rac family small GTPase 3 multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr17:82,031,678...82,034,204
Ensembl chr17:82,031,678...82,034,204
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RHOA ras homolog family member A multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,145...49,412,998
Ensembl chr 3:49,359,145...49,412,998
JBrowse link
G SLC22A1 solute carrier family 22 member 1 multiple interactions EXP Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr 6:160,121,808...160,160,590
Ensembl chr 6:160,121,815...160,158,718
JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
G SLC22A3 solute carrier family 22 member 3 increases uptake
multiple interactions
EXP SLC22A3 protein results in increased uptake of Atropine
Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]
CTD PMID:16263091 NCBI chr 6:160,348,378...160,454,982
Ensembl chr 6:160,348,378...160,452,577
JBrowse link
G SLC22A4 solute carrier family 22 member 4 multiple interactions EXP Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr 5:132,294,384...132,344,199
Ensembl chr 5:132,294,394...132,344,190
JBrowse link
G SLC47A1 solute carrier family 47 member 1 multiple interactions EXP Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034
JBrowse link
G SLC47A2 solute carrier family 47 member 2 multiple interactions EXP Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr17:19,678,313...19,719,598
Ensembl chr17:19,678,288...19,718,979
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G SPN sialophorin increases response to substance ISO SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876
JBrowse link
G TAT tyrosine aminotransferase multiple interactions ISO [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRIO trio Rho guanine nucleotide exchange factor multiple interactions EXP Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr 5:14,143,342...14,510,204
Ensembl chr 5:14,143,342...14,532,128
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 decreases response to substance ISO TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 8:72,021,250...72,094,885
Ensembl chr 8:72,019,917...72,075,584
JBrowse link
G TSHB thyroid stimulating hormone subunit beta multiple interactions ISO [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 1:115,029,826...115,035,935
Ensembl chr 1:115,029,826...115,034,302
Ensembl chr 1:115,029,826...115,034,302
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase affects expression ISO Cocaine affects the expression of AACS mRNA CTD PMID:20187946 NCBI chr12:125,065,435...125,143,327
Ensembl chr12:125,065,434...125,143,333
JBrowse link
G AADAC arylacetamide deacetylase decreases expression ISO Cocaine results in decreased expression of AADAC mRNA CTD PMID:17898221 NCBI chr 3:151,814,008...151,828,488
Ensembl chr 3:151,814,073...151,828,488
JBrowse link
G AANAT aralkylamine N-acetyltransferase affects response to substance ISO AANAT protein affects the susceptibility to Cocaine CTD PMID:12138020 NCBI chr17:76,453,351...76,470,797
Ensembl chr17:76,453,351...76,470,117
JBrowse link
G ABAT 4-aminobutyrate aminotransferase increases response to substance ISO ABAT mRNA results in increased susceptibility to Cocaine CTD PMID:10850552 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575
JBrowse link
G ABCA4 ATP binding cassette subfamily A member 4 decreases expression ISO Cocaine results in decreased expression of ABCA4 mRNA CTD PMID:27899881 NCBI chr 1:93,992,834...94,121,148
Ensembl chr 1:93,992,834...94,121,148
JBrowse link
G ABCA5 ATP binding cassette subfamily A member 5 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA] CTD PMID:17988634 NCBI chr17:69,244,311...69,327,133
Ensembl chr17:69,244,311...69,327,244
JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 affects expression ISO Cocaine affects the expression of ABCC3 mRNA CTD PMID:20187946 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 affects expression ISO Cocaine affects the expression of ABCC5 mRNA CTD PMID:20187946 NCBI chr 3:183,919,934...184,018,010
Ensembl chr 3:183,919,934...184,017,939
JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 affects expression ISO Cocaine affects the expression of ABCC9 mRNA CTD PMID:20187946 NCBI chr12:21,797,389...21,941,863
Ensembl chr12:21,797,401...21,942,529
JBrowse link
G ABCD4 ATP binding cassette subfamily D member 4 affects expression ISO Cocaine affects the expression of ABCD4 mRNA CTD PMID:20187946 NCBI chr14:74,285,269...74,303,062
Ensembl chr14:74,285,269...74,303,055
JBrowse link
G ABHD1 abhydrolase domain containing 1 decreases expression ISO Cocaine results in decreased expression of ABHD1 mRNA CTD PMID:18355967 NCBI chr 2:27,123,780...27,131,114
Ensembl chr 2:27,123,789...27,130,812
JBrowse link
G ABHD14A abhydrolase domain containing 14A affects expression ISO Cocaine affects the expression of ABHD14A mRNA CTD PMID:20187946 NCBI chr 3:51,975,064...51,981,196
Ensembl chr 3:51,971,426...51,981,199
JBrowse link
G ABHD17A abhydrolase domain containing 17A, depalmitoylase affects expression ISO Cocaine affects the expression of ABHD17A mRNA CTD PMID:20187946 NCBI chr19:1,876,810...1,885,519
Ensembl chr19:1,876,810...1,885,496
Ensembl chr19:1,876,810...1,885,496
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase affects expression ISO Cocaine affects the expression of ABL1 mRNA CTD PMID:15681117 NCBI chr 9:130,713,881...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 increases expression ISO Cocaine results in increased expression of ACAA1 mRNA CTD PMID:18355967 NCBI chr 3:38,122,710...38,137,127
Ensembl chr 3:38,103,129...38,137,242
JBrowse link
G ACAN aggrecan affects expression ISO Cocaine affects the expression of ACAN mRNA CTD PMID:20187946 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,354
Ensembl chr15:88,803,436...88,875,354
Ensembl chr15:88,803,436...88,875,354
JBrowse link
G ACE angiotensin I converting enzyme multiple interactions EXP ACE inhibits the reaction [Cocaine affects the abundance of Dinoprostone]; ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACIN1 apoptotic chromatin condensation inducer 1 affects expression ISO Cocaine affects the expression of ACIN1 mRNA CTD PMID:15681117 NCBI chr14:23,058,564...23,095,614
Ensembl chr14:23,058,564...23,095,614
JBrowse link
G ACKR2 atypical chemokine receptor 2 affects expression ISO Cocaine affects the expression of ACKR2 mRNA CTD PMID:20187946 NCBI chr 3:42,809,445...42,867,286
Ensembl chr 3:42,804,752...42,887,974
JBrowse link
G ACO2 aconitase 2 increases expression ISO Cocaine results in increased expression of ACO2 protein modified form CTD PMID:24096156 NCBI chr22:41,468,756...41,528,979
Ensembl chr22:41,469,117...41,528,989
Ensembl chr22:41,469,117...41,528,989
JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 affects expression ISO Cocaine affects the expression of ACSL5 mRNA CTD PMID:20187946 NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,018...112,428,380
JBrowse link
G ACSS1 acyl-CoA synthetase short chain family member 1 decreases expression ISO Cocaine results in decreased expression of ACSS1 mRNA CTD PMID:27899881 NCBI chr20:25,006,232...25,058,143
Ensembl chr20:25,006,230...25,058,980
JBrowse link
G ACTG2 actin gamma 2, smooth muscle decreases expression EXP Cocaine results in decreased expression of ACTG2 mRNA CTD PMID:20948987 NCBI chr 2:73,893,008...73,919,865
Ensembl chr 2:73,892,314...73,919,865
JBrowse link
G ACTN2 actinin alpha 2 increases expression EXP Cocaine results in increased expression of ACTN2 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 1:236,686,499...236,764,631
Ensembl chr 1:236,664,141...236,764,631
JBrowse link
G ACVR1C activin A receptor type 1C increases expression ISO Cocaine results in increased expression of ACVR1C mRNA CTD PMID:17898221 NCBI chr 2:157,526,767...157,628,864
Ensembl chr 2:157,526,767...157,628,864
JBrowse link
G ACY3 aminoacylase 3 affects expression ISO Cocaine affects the expression of ACY3 mRNA CTD PMID:20187946 NCBI chr11:67,642,551...67,650,829
Ensembl chr11:67,642,555...67,650,730
JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 decreases expression ISO Cocaine results in decreased expression of ADAM19 mRNA CTD PMID:17898221 NCBI chr 5:157,477,304...157,575,775
Ensembl chr 5:157,395,534...157,575,775
JBrowse link
G ADAM1A ADAM metallopeptidase domain 1A (pseudogene) multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA] CTD PMID:17988634 NCBI chr12:111,899,063...111,901,902
Ensembl chr12:111,899,263...111,901,391
JBrowse link
G ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif 19 decreases expression ISO Cocaine results in decreased expression of ADAMTS19 mRNA CTD PMID:27899881 NCBI chr 5:129,460,281...129,738,683
Ensembl chr 5:129,460,281...129,738,683
JBrowse link
G ADAT2 adenosine deaminase tRNA specific 2 decreases expression ISO Cocaine results in decreased expression of ADAT2 mRNA CTD PMID:17898221 NCBI chr 6:143,422,832...143,450,750
Ensembl chr 6:143,422,832...143,450,695
JBrowse link
G ADCY2 adenylate cyclase 2 affects expression ISO Cocaine affects the expression of ADCY2 mRNA CTD PMID:20187946 NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081
JBrowse link
G ADCY8 adenylate cyclase 8 affects expression ISO Cocaine affects the expression of ADCY8 mRNA CTD PMID:20187946 NCBI chr 8:130,780,300...131,041,604
Ensembl chr 8:130,780,301...131,040,909
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 multiple interactions
increases expression
ISO ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA] CTD PMID:29673861 NCBI chr18:904,384...912,172
Ensembl chr18:904,871...912,172
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I multiple interactions
increases expression
ISO alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA] CTD PMID:29673861 NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,479
Ensembl chr 7:31,052,308...31,111,479
JBrowse link
G ADGRA1 adhesion G protein-coupled receptor A1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA CTD PMID:18355967 NCBI chr10:133,087,924...133,131,675
Ensembl chr10:133,070,929...133,131,675
JBrowse link
G ADGRE1 adhesion G protein-coupled receptor E1 affects expression ISO Cocaine affects the expression of ADGRE1 mRNA CTD PMID:20187946 NCBI chr19:6,887,549...6,940,450
Ensembl chr19:6,887,566...6,940,459
JBrowse link
G ADGRF1 adhesion G protein-coupled receptor F1 decreases expression ISO Cocaine results in decreased expression of ADGRF1 mRNA CTD PMID:17898221 NCBI chr 6:46,997,708...47,042,350
Ensembl chr 6:46,997,708...47,042,350
JBrowse link
G ADGRL1 adhesion G protein-coupled receptor L1 affects expression ISO Cocaine affects the expression of ADGRL1 mRNA CTD PMID:20187946 NCBI chr19:14,147,737...14,206,245
Ensembl chr19:14,147,743...14,206,187
JBrowse link
G ADGRL3 adhesion G protein-coupled receptor L3 affects expression ISO Cocaine affects the expression of ADGRL3 mRNA CTD PMID:20187946 NCBI chr 4:61,200,326...62,078,335
Ensembl chr 4:61,201,258...62,078,335
JBrowse link
G ADORA1 adenosine A1 receptor affects expression
affects response to substance
ISO Cocaine affects the expression of ADORA1 mRNA; Cocaine affects the expression of ADORA1 protein
ADORA1 affects the susceptibility to Cocaine
CTD PMID:12358776 PMID:19092996 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADORA2A adenosine A2a receptor increases response to substance ISO ADORA2A results in increased susceptibility to Cocaine CTD PMID:16123743 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G ADORA2B adenosine A2b receptor affects expression ISO Cocaine affects the expression of ADORA2B mRNA CTD PMID:20187946 NCBI chr17:15,927,782...15,975,746
Ensembl chr17:15,944,917...15,975,746
JBrowse link
G ADRA1B adrenoceptor alpha 1B increases response to substance ISO ADRA1B gene results in increased susceptibility to Cocaine CTD PMID:14556232 NCBI chr 5:159,916,482...159,989,205
Ensembl chr 5:159,865,080...159,973,012
JBrowse link
G ADRB1 adrenoceptor beta 1 multiple interactions
affects expression
ISO Betaxolol affects the reaction [Cocaine affects the expression of ADRB1 protein]; Betaxolol inhibits the reaction [Cocaine affects the expression of ADRB1 protein] CTD PMID:17513029 PMID:18596687 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G AFF4 AF4/FMR2 family member 4 increases expression ISO Cocaine results in increased expression of AFF4 mRNA CTD PMID:17898221 NCBI chr 5:132,875,381...132,963,655
Ensembl chr 5:132,875,395...132,963,634
JBrowse link
G AFMID arylformamidase increases expression ISO Cocaine results in increased expression of AFMID mRNA CTD PMID:17898221 NCBI chr17:78,185,102...78,207,702
Ensembl chr17:78,187,317...78,207,701
JBrowse link
G AFP alpha fetoprotein increases expression ISO Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 affects expression ISO Cocaine affects the expression of AGAP2 mRNA CTD PMID:20187946 NCBI chr12:57,723,761...57,742,201
Ensembl chr12:57,723,761...57,742,157
JBrowse link
G AGO2 argonaute RISC catalytic component 2 multiple interactions
affects response to substance
ISO AGO2 protein affects the reaction [Cocaine results in increased expression of MIR130A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR136 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR137 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR138-1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR148B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR154 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR181A1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR186 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR301B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR324 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR337 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR369 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376C mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR380 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR384 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR467B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR488 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR500 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR544 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR665 mRNA]
AGO2 protein affects the susceptibility to Cocaine
CTD PMID:20643829 NCBI chr 8:140,520,156...140,642,406
Ensembl chr 8:140,520,156...140,635,633
JBrowse link
G AIF1L allograft inflammatory factor 1 like decreases expression EXP Cocaine results in decreased expression of AIF1L mRNA CTD PMID:15009677 NCBI chr 9:131,096,531...131,123,144
Ensembl chr 9:131,096,476...131,123,152
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of AIFM1 mRNA
Cocaine results in increased expression of AIFM1 mRNA
CTD PMID:15681117 PMID:18000554 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G AIFM2 apoptosis inducing factor mitochondria associated 2 affects expression ISO Cocaine affects the expression of AIFM2 mRNA CTD PMID:15681117 NCBI chr10:70,112,271...70,132,825
Ensembl chr10:70,098,223...70,132,934
JBrowse link
G AK1 adenylate kinase 1 decreases expression EXP Cocaine results in decreased expression of AK1 mRNA CTD PMID:15009677 NCBI chr 9:127,866,480...127,885,542
Ensembl chr 9:127,866,486...127,877,675
JBrowse link
G AK3 adenylate kinase 3 affects expression ISO Cocaine affects the expression of AK3 mRNA CTD PMID:20187946 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
JBrowse link
G AKR1D1 aldo-keto reductase family 1 member D1 affects expression ISO Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 NCBI chr 7:138,076,459...138,118,305
Ensembl chr 7:138,002,324...138,118,305
JBrowse link
G AKR1E2 aldo-keto reductase family 1 member E2 affects expression ISO Cocaine affects the expression of AKR1E1 mRNA CTD PMID:20187946 NCBI chr10:4,824,554...4,908,421
Ensembl chr10:4,786,629...4,848,062
JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 affects expression ISO Cocaine affects the expression of AKR7A3 mRNA CTD PMID:20187946 NCBI chr 1:19,274,229...19,289,362
Ensembl chr 1:19,282,573...19,288,770
JBrowse link
G AKT1 AKT serine/threonine kinase 1 affects expression
multiple interactions
increases phosphorylation
ISO Cocaine affects the expression of AKT1 mRNA
[Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein
Cocaine results in increased phosphorylation of AKT1 protein
Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]
CTD PMID:18702665 PMID:20187946 PMID:25933444 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALCAM activated leukocyte cell adhesion molecule increases expression ISO Cocaine results in increased expression of ALCAM mRNA CTD PMID:17898221 NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member multiple interactions ISO [[CVT-10216 results in decreased activity of ALDH2 protein] which results in increased abundance of Tetrahydropapaveroline] inhibits the reaction [Cocaine results in increased abundance of and results in increased secretion of Dopamine]; [ALDH2 protein affects the abundance of Tetrahydropapaveroline] which affects the susceptibility to Cocaine; ALDH2 protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:20729865 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G AMBRA1 autophagy and beclin 1 regulator 1 decreases expression ISO Cocaine results in decreased expression of AMBRA1 mRNA CTD PMID:17898221 NCBI chr11:46,396,412...46,594,055
Ensembl chr11:46,396,414...46,594,125
JBrowse link
G AMH anti-Mullerian hormone increases expression ISO Cocaine results in increased expression of AMH mRNA CTD PMID:17898221 NCBI chr19:2,249,323...2,252,073
Ensembl chr19:2,249,309...2,252,073
JBrowse link
G AMIGO1 adhesion molecule with Ig like domain 1 affects expression ISO Cocaine affects the expression of AMIGO1 mRNA CTD PMID:20187946 NCBI chr 1:109,504,178...109,509,742
Ensembl chr 1:109,504,178...109,509,738
JBrowse link
G AMIGO3 adhesion molecule with Ig like domain 3 affects expression ISO Cocaine affects the expression of AMIGO3 mRNA CTD PMID:20187946 NCBI chr 3:49,716,829...49,719,684
Ensembl chr 3:49,716,829...49,719,684
JBrowse link
G AMN1 antagonist of mitotic exit network 1 homolog decreases expression ISO Cocaine results in decreased expression of AMN1 mRNA CTD PMID:17898221 NCBI chr12:31,671,137...31,729,174
Ensembl chr12:31,671,142...31,729,121
JBrowse link
G ANKRD54 ankyrin repeat domain 54 affects expression ISO Cocaine affects the expression of ANKRD54 mRNA CTD PMID:20187946 NCBI chr22:37,830,853...37,849,341
Ensembl chr22:37,830,855...37,849,327
JBrowse link
G ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Cocaine results in decreased expression of ANKS1B mRNA CTD PMID:17898221 NCBI chr12:98,729,904...99,984,936
Ensembl chr12:98,726,457...99,984,654
JBrowse link
G ANXA7 annexin A7 affects expression ISO Cocaine affects the expression of ANXA7 mRNA CTD PMID:20187946 NCBI chr10:73,375,101...73,414,058
Ensembl chr10:73,375,101...73,414,076
JBrowse link
G AP1AR adaptor related protein complex 1 associated regulatory protein increases expression ISO Cocaine results in increased expression of AP1AR mRNA CTD PMID:17898221 NCBI chr 4:112,231,787...112,273,110
Ensembl chr 4:112,231,740...112,273,110
JBrowse link
G AP2B1 adaptor related protein complex 2 subunit beta 1 affects expression ISO Cocaine affects the expression of AP2B1 mRNA CTD PMID:20187946 NCBI chr17:35,587,265...35,726,413
Ensembl chr17:35,578,046...35,726,413
JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 increases expression ISO Cocaine results in increased expression of AP2M1 protein CTD PMID:25100957 NCBI chr 3:184,174,855...184,184,091
Ensembl chr 3:184,174,689...184,184,091
JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 decreases expression EXP Cocaine results in decreased expression of AP2S1 mRNA CTD PMID:15009677 NCBI chr19:46,838,167...46,850,846
Ensembl chr19:46,838,136...46,850,992
Ensembl chr19:46,838,136...46,850,992
JBrowse link
G AP5M1 adaptor related protein complex 5 subunit mu 1 affects expression ISO Cocaine affects the expression of AP5M1 mRNA CTD PMID:20187946 NCBI chr14:57,268,915...57,298,742
Ensembl chr14:57,268,924...57,298,742
JBrowse link
G APCS amyloid P component, serum increases expression EXP Cocaine results in increased expression of APCS protein CTD PMID:12714198 NCBI chr 1:159,587,826...159,588,865
Ensembl chr 1:159,587,826...159,588,865
JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit affects expression ISO Cocaine affects the expression of APH1A mRNA CTD PMID:20187946 NCBI chr 1:150,265,404...150,282,179
Ensembl chr 1:150,265,399...150,269,580
JBrowse link
G APLNR apelin receptor increases expression ISO Cocaine results in increased expression of APLNR mRNA CTD PMID:17898221 NCBI chr11:57,233,591...57,237,430
Ensembl chr11:57,233,577...57,237,235
Ensembl chr11:57,233,577...57,237,235
JBrowse link
G APOL2 apolipoprotein L2 increases expression EXP Cocaine results in increased expression of APOL2 mRNA CTD PMID:17205118 NCBI chr22:36,226,209...36,239,954
Ensembl chr22:36,226,209...36,239,954
JBrowse link
G APOLD1 apolipoprotein L domain containing 1 affects expression ISO Cocaine affects the expression of APOLD1 mRNA CTD PMID:20187946 NCBI chr12:12,725,917...12,791,466
Ensembl chr12:12,725,917...12,829,975
JBrowse link
G APOO apolipoprotein O increases expression ISO Cocaine results in increased expression of APOO protein CTD PMID:25100957 NCBI chr  X:23,833,348...23,907,938
Ensembl chr  X:23,833,353...23,907,938
JBrowse link
G APP amyloid beta precursor protein decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of APP mRNA
Cocaine results in increased expression of APP mRNA
CTD PMID:15009677 PMID:16710320 PMID:17898221 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 increases expression ISO Cocaine results in increased expression of APPL1 mRNA CTD PMID:17898221 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105
JBrowse link
G ARC activity regulated cytoskeleton associated protein affects expression
increases expression
multiple interactions
ISO Cocaine affects the expression of ARC mRNA
Cocaine results in increased expression of ARC mRNA; Cocaine results in increased expression of ARC protein
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]
CTD PMID:7722525 PMID:12117546 PMID:15254092 PMID:17851536 PMID:18311559 PMID:18361437 PMID:20187946 PMID:24810662 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G ARF4 ADP ribosylation factor 4 decreases expression ISO Cocaine results in decreased expression of ARF4 protein CTD PMID:25100957 NCBI chr 3:57,571,363...57,597,344
Ensembl chr 3:57,571,363...57,598,220
JBrowse link
G ARHGAP1 Rho GTPase activating protein 1 increases expression ISO Cocaine results in increased expression of ARHGAP1 protein CTD PMID:25100957 NCBI chr11:46,677,077...46,700,660
Ensembl chr11:46,677,080...46,700,619
JBrowse link
G ARHGAP29 Rho GTPase activating protein 29 decreases expression EXP Cocaine results in decreased expression of ARHGAP29 mRNA CTD PMID:12629581 NCBI chr 1:94,168,905...94,275,068
Ensembl chr 1:94,148,988...94,275,068
JBrowse link
G ARHGAP30 Rho GTPase activating protein 30 increases expression ISO Cocaine results in increased expression of ARHGAP30 mRNA CTD PMID:17898221 NCBI chr 1:161,046,942...161,069,971
Ensembl chr 1:161,046,946...161,069,970
JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 decreases expression ISO Cocaine results in decreased expression of ARHGAP44 protein CTD PMID:25100957 NCBI chr17:12,789,498...12,991,644
Ensembl chr17:12,789,498...12,991,643
JBrowse link
G ARHGAP5 Rho GTPase activating protein 5 increases expression ISO Cocaine results in increased expression of ARHGAP5 mRNA CTD PMID:17898221 NCBI chr14:32,072,588...32,159,728
Ensembl chr14:32,076,114...32,159,728
JBrowse link
G ARHGAP9 Rho GTPase activating protein 9 decreases expression ISO Cocaine results in decreased expression of ARHGAP9 mRNA CTD PMID:17898221 NCBI chr12:57,472,262...57,488,824
Ensembl chr12:57,472,264...57,488,814
JBrowse link
G ARHGEF1 Rho guanine nucleotide exchange factor 1 affects expression ISO Cocaine affects the expression of ARHGEF1 mRNA CTD PMID:20187946 NCBI chr19:41,883,184...41,907,452
Ensembl chr19:41,883,173...41,930,150
JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 affects expression ISO Cocaine affects the expression of ARHGEF7 mRNA CTD PMID:20187946 NCBI chr13:111,114,619...111,305,734
Ensembl chr13:111,114,559...111,305,737
JBrowse link
G ARMCX6 armadillo repeat containing X-linked 6 affects expression ISO Cocaine affects the expression of ARMCX6 mRNA CTD PMID:20187946 NCBI chr  X:101,615,120...101,618,000
Ensembl chr  X:101,615,118...101,618,001
JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like decreases expression ISO Cocaine results in decreased expression of ARNTL mRNA CTD PMID:15994025 NCBI chr11:13,276,552...13,387,268
Ensembl chr11:13,276,652...13,387,266
JBrowse link
G ARPC1A actin related protein 2/3 complex subunit 1A increases expression ISO Cocaine results in increased expression of ARPC1A protein CTD PMID:25100957 NCBI chr 7:99,325,898...99,366,262
Ensembl chr 7:99,325,898...99,366,262
JBrowse link
G ARPP19 cAMP regulated phosphoprotein 19 multiple interactions ISO Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP19 protein] CTD PMID:11268215 NCBI chr15:52,547,045...52,569,446
Ensembl chr15:52,547,045...52,569,883
JBrowse link
G ARPP21 cAMP regulated phosphoprotein 21 multiple interactions ISO Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP21 protein] CTD PMID:11268215 NCBI chr 3:35,638,853...35,798,933
Ensembl chr 3:35,638,945...35,794,496
JBrowse link
G ART5 ADP-ribosyltransferase 5 increases expression ISO Cocaine results in increased expression of ART5 mRNA CTD PMID:17898221 NCBI chr11:3,638,503...3,642,392
Ensembl chr11:3,638,512...3,642,316
JBrowse link
G AS3MT arsenite methyltransferase affects expression ISO Cocaine affects the expression of AS3MT mRNA CTD PMID:20187946 NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899
JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression ISO Cocaine results in decreased expression of ASAP1 mRNA CTD PMID:17898221 NCBI chr 8:130,052,104...130,443,848
Ensembl chr 8:130,052,104...130,443,674
JBrowse link
G ATAD1 ATPase family AAA domain containing 1 increases expression ISO Cocaine results in increased expression of ATAD1 mRNA CTD PMID:17898221 NCBI chr10:87,751,512...87,841,359
Ensembl chr10:87,751,512...87,841,343
JBrowse link
G ATAD5 ATPase family AAA domain containing 5 decreases expression ISO Cocaine results in decreased expression of ATAD5 mRNA CTD PMID:17898221 NCBI chr17:30,830,830...30,895,869
Ensembl chr17:30,831,966...30,895,869
JBrowse link
G ATE1 arginyltransferase 1 increases expression ISO Cocaine results in increased expression of ATE1 mRNA CTD PMID:17898221 NCBI chr10:121,740,424...121,928,801
Ensembl chr10:121,740,421...121,928,801
Ensembl chr10:121,740,421...121,928,801
JBrowse link
G ATF3 activating transcription factor 3 increases expression
decreases expression
ISO Cocaine results in increased expression of ATF3 mRNA
Cocaine results in decreased expression of ATF3 mRNA
CTD PMID:23644055 PMID:27899881 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF4 activating transcription factor 4 increases expression ISO Cocaine results in increased expression of ATF4; Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214 PMID:23644055 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
JBrowse link
G ATF6 activating transcription factor 6 affects expression ISO Cocaine affects the expression of ATF6 mRNA CTD PMID:23644055 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,320...161,964,070
JBrowse link
G ATF7 activating transcription factor 7 affects expression ISO Cocaine affects the expression of ATF7 mRNA CTD PMID:15681117 NCBI chr12:53,507,856...53,626,382
Ensembl chr12:53,507,856...53,626,410
JBrowse link
G ATG2B autophagy related 2B affects expression ISO Cocaine affects the expression of ATG2B mRNA CTD PMID:20187946 NCBI chr14:96,279,195...96,363,341
Ensembl chr14:96,279,195...96,363,341
JBrowse link
G ATG4B autophagy related 4B cysteine peptidase affects expression ISO Cocaine affects the expression of ATG4B mRNA CTD PMID:20187946 NCBI chr 2:241,637,659...241,673,857
Ensembl chr 2:241,637,213...241,673,857
JBrowse link
G ATM ATM serine/threonine kinase multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
JBrowse link
G ATP10A ATPase phospholipid transporting 10A (putative) decreases expression ISO Cocaine results in decreased expression of ATP10A mRNA CTD PMID:17898221 PMID:27899881 NCBI chr15:25,672,241...25,865,144
Ensembl chr15:25,677,271...25,865,184
Ensembl chr15:25,677,271...25,865,184
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 affects expression ISO Cocaine affects the expression of ATP1A1 mRNA CTD PMID:18355967 NCBI chr 1:116,372,986...116,410,259
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 increases expression
affects expression
ISO Cocaine results in increased expression of ATP1A3 mRNA
Cocaine affects the expression of ATP1A3 mRNA
CTD PMID:16076954 PMID:20187946 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Cocaine results in increased expression of ATP1B2 mRNA CTD PMID:16076954 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP1B3 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]
CTD PMID:18355967 NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha affects expression EXP Cocaine affects the expression of ATP5F1A protein CTD PMID:19393250 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta decreases expression EXP Cocaine results in decreased expression of ATP5F1B protein CTD PMID:17075605 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G ATP5F1E ATP synthase F1 subunit epsilon affects expression ISO Cocaine affects the expression of ATP5F1E mRNA CTD PMID:20187946 NCBI chr20:59,025,475...59,032,335
Ensembl chr20:59,025,475...59,032,345
JBrowse link
G ATP5MC3 ATP synthase membrane subunit c locus 3 decreases expression
affects expression
EXP
ISO
Cocaine results in decreased expression of ATP5MC3 mRNA
Cocaine affects the expression of ATP5MC3 mRNA
CTD PMID:12629581 PMID:20187946 NCBI chr 2:175,176,258...175,181,710
Ensembl chr 2:175,176,258...175,184,607
Ensembl chr 2:175,176,258...175,184,607
JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b affects expression ISO Cocaine affects the expression of ATP5PB mRNA CTD PMID:20187946 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773
JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d affects expression ISO Cocaine affects the expression of ATP5H mRNA CTD PMID:12358776 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D affects expression ISO Cocaine affects the expression of ATP6V1D mRNA CTD PMID:20187946 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP8B2 ATPase phospholipid transporting 8B2 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP8B2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]
CTD PMID:18355967 NCBI chr 1:154,325,525...154,351,304
Ensembl chr 1:154,325,553...154,351,304
Ensembl chr 1:154,325,553...154,351,304
JBrowse link
G ATP9B ATPase phospholipid transporting 9B (putative) affects response to substance EXP ATP9B gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr18:79,069,285...79,378,391
Ensembl chr18:79,069,285...79,378,287
JBrowse link
G ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA CTD PMID:18355967 NCBI chr 1:46,632,737...46,668,443
Ensembl chr 1:46,632,737...46,673,867
JBrowse link
G ATRX ATRX chromatin remodeler increases expression ISO Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 NCBI chr  X:77,504,880...77,786,235
Ensembl chr  X:77,504,880...77,786,233
Ensembl chr  X:77,504,880...77,786,233
JBrowse link
G ATXN1 ataxin 1 affects expression ISO Cocaine affects the expression of ATXN1 mRNA CTD PMID:20187946 NCBI chr 6:16,299,112...16,761,490
Ensembl chr 6:16,299,112...16,761,491
JBrowse link
G ATXN3 ataxin 3 decreases expression EXP Cocaine results in decreased expression of ATXN3 mRNA CTD PMID:12629581 NCBI chr14:92,058,552...92,106,582
Ensembl chr14:92,044,496...92,106,621
JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO Cocaine results in decreased expression of AZGP1 mRNA CTD PMID:17898221 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042
JBrowse link
G BAALC BAALC binder of MAP3K1 and KLF4 decreases expression ISO Cocaine results in decreased expression of BAALC mRNA CTD PMID:18355967 NCBI chr 8:103,140,725...103,230,305
Ensembl chr 8:103,140,713...103,230,305
JBrowse link
G BACH1 BTB domain and CNC homolog 1 increases expression ISO Cocaine results in increased expression of BACH1 mRNA CTD PMID:17898221 NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751
JBrowse link
G BACH2 BTB domain and CNC homolog 2 affects expression ISO Cocaine affects the expression of BACH2 mRNA CTD PMID:15681117 NCBI chr 6:89,926,528...90,296,843
Ensembl chr 6:89,926,528...90,296,908
JBrowse link
G BAD BCL2 associated agonist of cell death affects expression ISO Cocaine affects the expression of BAD mRNA CTD PMID:15681117 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAG1 BAG cochaperone 1 affects expression ISO Cocaine affects the expression of BAG1 mRNA CTD PMID:15681117 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720
JBrowse link
G BAG3 BAG cochaperone 3 affects expression
increases expression
ISO Cocaine affects the expression of BAG3 mRNA
Cocaine results in increased expression of BAG3 mRNA
CTD PMID:15681117 PMID:27899881 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,370...119,677,819
Ensembl chr10:119,651,370...119,677,819
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor affects expression ISO Cocaine affects the expression of BAMBI mRNA CTD PMID:20187946 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BASP1 brain abundant membrane attached signal protein 1 affects expression ISO Cocaine affects the expression of BASP1 mRNA CTD PMID:20187946 NCBI chr 5:17,216,823...17,276,834
Ensembl chr 5:17,065,598...17,276,843
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
increases activity
affects expression
EXP
ISO
Cocaine results in increased expression of BAX mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]
Cocaine results in increased activity of BAX protein
Cocaine affects the expression of BAX mRNA
CTD PMID:11392460 PMID:15681117 PMID:15685203 PMID:17084983 PMID:17635674 PMID:18974856 PMID:20948987 PMID:29673861 PMID:30393195 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BAZ1B bromodomain adjacent to zinc finger domain 1B increases expression
multiple interactions
ISO Cocaine results in increased expression of BAZ1B mRNA
[SMARCA5 protein co-treated with BAZ1B protein] results in increased susceptibility to Cocaine; Cocaine promotes the reaction [BAZ1B protein binds to SPHKAP gene]; Cocaine results in increased expression of and affects the activity of BAZ1B protein
CTD PMID:27053203 NCBI chr 7:73,440,406...73,522,293
Ensembl chr 7:73,440,406...73,522,293
JBrowse link
G BAZ2B bromodomain adjacent to zinc finger domain 2B increases expression ISO Cocaine results in increased expression of BAZ2B mRNA CTD PMID:17898221 NCBI chr 2:159,315,312...159,712,442
Ensembl chr 2:159,318,979...159,616,569
Ensembl chr 2:159,318,979...159,616,569
JBrowse link
G BCAP31 B cell receptor associated protein 31 affects expression ISO Cocaine affects the expression of BCAP31 mRNA CTD PMID:20187946 NCBI chr  X:153,700,492...153,724,746
Ensembl chr  X:153,700,492...153,724,565
JBrowse link
G BCAT1 branched chain amino acid transaminase 1 affects expression ISO Cocaine affects the expression of BCAT1 mRNA CTD PMID:20187946 NCBI chr12:24,810,024...24,949,101
Ensembl chr12:24,810,024...24,949,101
JBrowse link
G BCHE butyrylcholinesterase affects metabolic processing
multiple interactions
increases hydrolysis
increases metabolic processing
decreases response to substance
affects hydrolysis
decreases metabolic processing
affects degradation
EXP
ISO
BCHE protein affects the metabolism of Cocaine
[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of Benzoic Acid; [BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl ester
[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of Benzoic Acid; [BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl ester
BCHE protein mutant form results in increased metabolism of Cocaine; BCHE protein results in increased metabolism of Cocaine
BCHE protein mutant form results in decreased susceptibility to Cocaine
BCHE protein modified form results in increased hydrolysis of Cocaine; BCHE protein mutant form results in increased hydrolysis of Cocaine
BCHE protein affects the hydrolysis of Cocaine
BCHE protein mutant form results in decreased metabolism of Cocaine
BCHE protein mutant form affects the degradation of Cocaine
CTD PMID:572161 PMID:16275916 PMID:17989928 PMID:18514178 PMID:18514640 PMID:19067679 PMID:20060817 PMID:20219449 PMID:20971807 PMID:22917637 PMID:22960160 PMID:24582612 PMID:25814464 PMID:27154495 PMID:30080993 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL2 BCL2 apoptosis regulator affects expression
multiple interactions
decreases expression
increases phosphorylation
increases expression
ISO Cocaine affects the expression of BCL2 mRNA
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]
Cocaine results in increased phosphorylation of BCL2 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
Cocaine results in decreased expression of BCL2 mRNA; Cocaine results in decreased expression of BCL2 protein
Cocaine results in increased expression of BCL2 protein
CTD PMID:11392460 PMID:15365088 PMID:15681117 PMID:15685203 PMID:17084983 PMID:18974856 PMID:19183502 PMID:19879923 PMID:29673861 PMID:30393195 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 increases expression
decreases expression
multiple interactions
ISO Cocaine results in increased expression of BCL2L1 mRNA; Cocaine results in increased expression of BCL2L1 mRNA alternative form
Cocaine results in decreased expression of BCL2L1 protein
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]
CTD PMID:16076954 PMID:29673861 PMID:30393195 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL2L11 BCL2 like 11 increases expression ISO Cocaine results in increased expression of BCL2L11 mRNA CTD PMID:16076954 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,445
JBrowse link
G BDNF brain derived neurotrophic factor decreases response to substance
increases expression
decreases activity
affects expression
multiple interactions
decreases expression
increases response to substance
EXP
ISO
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of BDNF mRNA
Cocaine results in decreased activity of BDNF protein
Cocaine results in increased expression of BDNF protein
Cocaine affects the expression of BDNF exon; Cocaine affects the expression of BDNF mRNA; Cocaine affects the expression of BDNF protein
BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]; Cocaine affects the activity of and affects the expression of BDNF protein; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]; Cocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine; BDNF results in decreased susceptibility to Cocaine
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; (+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; Cocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Cocaine results in decreased expression of BDNF mRNA; Cocaine results in decreased expression of BDNF protein
BDNF results in increased susceptibility to Cocaine
CTD PMID:12099907 PMID:14973246 PMID:16423334 PMID:17194538 PMID:17618281 PMID:18311559 PMID:18355967 PMID:19321768 PMID:20554863 PMID:20711185 PMID:20810894 PMID:20826313 PMID:24358339 PMID:26558777 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BEGAIN brain enriched guanylate kinase associated affects expression ISO Cocaine affects the expression of BEGAIN mRNA CTD PMID:20187946 NCBI chr14:100,537,147...100,587,417
Ensembl chr14:100,537,147...100,587,413
JBrowse link
G BHLHE22 basic helix-loop-helix family member e22 increases expression ISO Cocaine results in increased expression of BHLHE22 mRNA CTD PMID:17898221 NCBI chr 8:64,580,365...64,583,627
Ensembl chr 8:64,580,365...64,583,627
JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 affects expression ISO Cocaine affects the expression of BHLHE40 mRNA CTD PMID:20187946 NCBI chr 3:4,979,420...4,985,323
Ensembl chr 3:4,979,437...4,985,323
JBrowse link
G BID BH3 interacting domain death agonist affects expression ISO Cocaine affects the expression of BID mRNA CTD PMID:15681117 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
JBrowse link
G BIK BCL2 interacting killer affects expression ISO Cocaine affects the expression of BIK mRNA CTD PMID:15681117 NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,750...43,129,712
JBrowse link
G BMP2K BMP2 inducible kinase affects expression ISO Cocaine affects the expression of BMP2K mRNA CTD PMID:20187946 NCBI chr 4:78,776,350...78,916,365
Ensembl chr 4:78,776,342...78,916,372
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 increases expression ISO Cocaine results in increased expression of BMPR2 mRNA CTD PMID:17898221 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G BNIP2 BCL2 interacting protein 2 affects expression ISO Cocaine affects the expression of BNIP2 mRNA CTD PMID:15681117 NCBI chr15:59,659,146...59,689,320
Ensembl chr15:59,659,146...59,689,534
JBrowse link
G BNIP3 BCL2 interacting protein 3 affects expression ISO Cocaine affects the expression of BNIP3 mRNA CTD PMID:15681117 NCBI chr10:131,967,683...131,982,013
Ensembl chr10:131,966,455...131,982,013
JBrowse link
G BNIP3L BCL2 interacting protein 3 like affects expression ISO Cocaine affects the expression of BNIP3L mRNA CTD PMID:15681117 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636
JBrowse link
G BRD4 bromodomain containing 4 multiple interactions
increases expression
ISO (+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]
Cocaine results in increased expression of BRD4 protein
CTD PMID:26558777 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545
JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin affects expression ISO Cocaine affects the expression of BSCL2 mRNA CTD PMID:20187946 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,690,275...62,709,845
JBrowse link
G BST1 bone marrow stromal cell antigen 1 affects expression ISO Cocaine affects the expression of BST1 mRNA CTD PMID:20187946 NCBI chr 4:15,701,866...15,774,178
Ensembl chr 4:15,703,065...15,738,313
JBrowse link
G BTBD9 BTB domain containing 9 increases expression ISO Cocaine results in increased expression of BTBD9 mRNA CTD PMID:17898221 NCBI chr 6:38,168,451...38,640,541
Ensembl chr 6:38,168,451...38,640,148
JBrowse link
G BTG2 BTG anti-proliferation factor 2 affects expression ISO Cocaine affects the expression of BTG2 mRNA CTD PMID:20187946 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G BTK Bruton tyrosine kinase decreases expression ISO Cocaine results in decreased expression of BTK mRNA CTD PMID:17898221 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,447...101,390,796
JBrowse link
G C11orf96 chromosome 11 open reading frame 96 increases expression ISO Cocaine results in increased expression of RGD1564664 mRNA CTD PMID:27899881 NCBI chr11:43,942,637...43,943,878
Ensembl chr11:43,925,342...43,943,878
JBrowse link
G C1QBP complement C1q binding protein decreases expression ISO Cocaine results in decreased expression of C1QBP protein CTD PMID:25100957 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830
JBrowse link
G C1QTNF1 C1q and TNF related 1 affects expression ISO Cocaine affects the expression of C1QTNF1 mRNA CTD PMID:20187946 NCBI chr17:79,022,934...79,049,788
Ensembl chr17:79,022,814...79,049,788
JBrowse link
G C1QTNF4 C1q and TNF related 4 decreases expression ISO Cocaine results in decreased expression of C1QTNF4 mRNA CTD PMID:17898221 NCBI chr11:47,589,664...47,596,336
Ensembl chr11:47,589,667...47,594,411
JBrowse link
G C2CD3 C2 domain containing 3 centriole elongation regulator decreases expression ISO Cocaine results in decreased expression of C2CD3 mRNA CTD PMID:17898221 NCBI chr11:74,012,578...74,171,210
Ensembl chr11:74,012,714...74,171,210
Ensembl chr11:74,012,714...74,171,210
JBrowse link
G C2CD4D C2 calcium dependent domain containing 4D decreases expression ISO Cocaine results in decreased expression of C2CD4D mRNA CTD PMID:27899881 NCBI chr 1:151,837,818...151,840,557
Ensembl chr 1:151,837,819...151,840,557
JBrowse link
G CA4 carbonic anhydrase 4 decreases expression ISO Cocaine results in decreased expression of CAR4 mRNA CTD PMID:17898221 NCBI chr17:60,149,942...60,179,021
Ensembl chr17:60,149,942...60,170,899
JBrowse link
G CAB39L calcium binding protein 39 like multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA CTD PMID:18355967 NCBI chr13:49,308,650...49,444,851
Ensembl chr13:49,308,650...49,444,064
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D affects response to substance EXP CACNA1D polymorphism affects the susceptibility to Cocaine CTD PMID:28194001 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 affects expression ISO Cocaine affects the expression of CACNB3 mRNA CTD PMID:20187946 NCBI chr12:48,814,432...48,828,941
Ensembl chr12:48,813,794...48,828,941
JBrowse link
G CALD1 caldesmon 1 affects expression ISO Cocaine affects the expression of CALD1 mRNA CTD PMID:20187946 NCBI chr 7:134,779,629...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CALM1 calmodulin 1 decreases expression EXP Cocaine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 decreases expression EXP Cocaine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,083...47,176,921
JBrowse link
G CALR calreticulin decreases expression
multiple interactions
affects expression
ISO Cocaine results in decreased expression of CALR mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]
Cocaine affects the expression of CALR mRNA
CTD PMID:18355967 PMID:20187946 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CALY calcyon neuron specific vesicular protein increases expression ISO Cocaine results in increased expression of CALY mRNA CTD PMID:20171207 NCBI chr10:133,324,072...133,336,896
Ensembl chr10:133,324,072...133,336,935
JBrowse link
G CAMK1G calcium/calmodulin dependent protein kinase IG multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA CTD PMID:18355967 NCBI chr 1:209,583,714...209,613,939
Ensembl chr 1:209,583,714...209,613,939
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha affects response to substance
multiple interactions
increases expression
ISO CAMK2A affects the susceptibility to Cocaine
Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]
Cocaine results in increased expression of CAMK2A protein
7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
CTD PMID:14725635 PMID:17609678 PMID:19217379 PMID:28194001 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,291
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta decreases expression
affects expression
EXP
ISO
Cocaine results in decreased expression of CAMK2B mRNA
Cocaine affects the expression of CAMK2B mRNA
CTD PMID:17205118 PMID:20187946 NCBI chr 7:44,217,154...44,326,167
Ensembl chr 7:44,217,150...44,334,577
JBrowse link
G CAMK4 calcium/calmodulin dependent protein kinase IV increases response to substance
decreases response to substance
EXP
ISO
CAMK4 promoter SNP results in increased susceptibility to Cocaine
CAMK4 protein results in decreased susceptibility to Cocaine
CTD PMID:19001277 NCBI chr 5:111,223,583...111,498,503
Ensembl chr 5:111,223,653...111,494,886
JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 affects expression ISO Cocaine affects the expression of CAP2 mRNA CTD PMID:20187946 NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,505...17,557,790
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta decreases expression EXP Cocaine results in decreased expression of CAPZB mRNA CTD PMID:12629581 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G CARD11 caspase recruitment domain family member 11 decreases expression ISO Cocaine results in decreased expression of CARD11 mRNA CTD PMID:27899881 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,141...3,043,945
Ensembl chr 7:2,906,141...3,043,945
JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 affects expression ISO Cocaine affects the expression of CARM1 mRNA CTD PMID:20187946 NCBI chr19:10,871,553...10,923,078
Ensembl chr19:10,871,513...10,923,070
Ensembl chr19:10,871,513...10,923,070
JBrowse link
G CARNMT1 carnosine N-methyltransferase 1 affects expression ISO Cocaine affects the expression of CARNMT1 mRNA CTD PMID:20187946 NCBI chr 9:74,980,790...75,028,456
Ensembl chr 9:74,980,790...75,028,423
JBrowse link
G CARTPT CART prepropeptide increases expression
affects expression
EXP
ISO
Cocaine results in increased expression of CARTPT mRNA
Cocaine affects the expression of CARTPT mRNA
CTD PMID:15009677 PMID:17851536 PMID:20187946 NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048
JBrowse link
G CASP2 caspase 2 increases activity
increases expression
ISO Cocaine results in increased activity of CASP2 protein
Cocaine results in increased expression of CASP2 mRNA
CTD PMID:16076954 PMID:16638611 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
JBrowse link
G CASP3 caspase 3 increases expression
increases cleavage
multiple interactions
increases activity
affects expression
EXP
ISO
Cocaine results in increased expression of CASP3 protein
Cocaine results in increased cleavage of CASP3 protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]
Cocaine results in increased activity of CASP3 protein
Cocaine affects the expression of CASP3 protein
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Cocaine results in increased cleavage of and results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP3 protein]
Cocaine affects the expression of CASP3 mRNA
CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:14741756 PMID:15365088 PMID:15681117 PMID:16179556 PMID:16638611 PMID:16686379 PMID:17084983 PMID:17635674 PMID:18974856 PMID:19183502 PMID:20600547 PMID:29673861 PMID:30393195 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP4 caspase 4 affects expression
decreases expression
ISO
EXP
Cocaine affects the expression of CASP4 mRNA
Cocaine results in decreased expression of CASP4 mRNA
CTD PMID:12629581 PMID:15681117 NCBI chr11:104,942,866...104,968,596
Ensembl chr11:104,942,866...104,969,366
JBrowse link
G CASP8 caspase 8 affects expression
increases activity
ISO Cocaine affects the expression of CASP8 mRNA
Cocaine results in increased activity of CASP8 protein
CTD PMID:11392460 PMID:15681117 PMID:18974856 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 affects expression
increases activity
multiple interactions
increases expression
ISO
EXP
Cocaine affects the expression of CASP9 mRNA
Cocaine results in increased activity of CASP9 protein
SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP9 protein]
Cocaine affects the expression of CASP9 protein
Cocaine results in increased expression of CASP9 protein
CTD PMID:10604926 PMID:11392460 PMID:12639677 PMID:15365088 PMID:15681117 PMID:16179556 PMID:16638611 PMID:16686379 PMID:17084983 PMID:17635674 PMID:18974856 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 affects expression ISO Cocaine affects the expression of CASTOR1 mRNA CTD PMID:20187946 NCBI chr22:30,285,117...30,289,505
Ensembl chr22:30,285,117...30,289,627
Ensembl chr22:30,285,117...30,289,627
JBrowse link
G CAT catalase decreases activity
increases activity
increases expression
ISO Cocaine results in decreased activity of CAT protein
Cocaine results in increased activity of CAT protein
Cocaine results in increased expression of CAT protein
CTD PMID:14576513 PMID:16085363 PMID:29475069 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CATSPER2 cation channel sperm associated 2 increases expression ISO Cocaine results in increased expression of CATSPER2 mRNA CTD PMID:17898221 NCBI chr15:43,628,503...43,648,884
Ensembl chr15:43,628,503...43,668,118
JBrowse link
G CBLN1 cerebellin 1 precursor multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA CTD PMID:18355967 NCBI chr16:49,277,917...49,281,838
Ensembl chr16:49,277,917...49,281,838
JBrowse link
G CCDC127 coiled-coil domain containing 127 increases expression ISO Cocaine results in increased expression of CCDC127 mRNA CTD PMID:17898221 NCBI chr 5:196,868...218,153
Ensembl chr 5:196,868...218,153
JBrowse link
G CCDC174 coiled-coil domain containing 174 affects expression ISO Cocaine affects the expression of CCDC174 mRNA CTD PMID:20187946 NCBI chr 3:14,651,762...14,672,659
Ensembl chr 3:14,651,746...14,672,659
JBrowse link
G CCDC73 coiled-coil domain containing 73 decreases expression ISO Cocaine results in decreased expression of CCDC73 mRNA CTD PMID:17898221 NCBI chr11:32,602,721...32,794,662
Ensembl chr11:32,602,246...32,794,658
JBrowse link
G CCDC88A coiled-coil domain containing 88A increases expression ISO Cocaine results in increased expression of CCDC88A mRNA CTD PMID:17898221 NCBI chr 2:55,287,817...55,419,856
Ensembl chr 2:55,287,842...55,419,895
JBrowse link
G CCDC93 coiled-coil domain containing 93 increases expression ISO Cocaine results in increased expression of CCDC93 mRNA CTD PMID:17898221 NCBI chr 2:117,915,481...118,014,163
Ensembl chr 2:117,915,478...118,014,133
JBrowse link
G CCKBR cholecystokinin B receptor decreases expression
increases response to substance
EXP
ISO
Cocaine results in decreased expression of CCKBR mRNA
CCKBR protein results in increased susceptibility to Cocaine
CTD PMID:11403953 PMID:18000554 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases secretion
increases expression
multiple interactions
EXP
ISO
Cocaine results in increased secretion of CCL2 protein
Cocaine results in increased expression of CCL2 protein
Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]
CTD PMID:10065903 PMID:20354174 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL3 C-C motif chemokine ligand 3 increases secretion EXP Cocaine results in increased secretion of CCL3 protein CTD PMID:10065903 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCN2 cellular communication network factor 2 decreases expression EXP Cocaine results in decreased expression of CCN2 mRNA; Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCN3 cellular communication network factor 3 increases expression ISO Cocaine results in increased expression of CCN3 mRNA CTD PMID:17898221 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434
JBrowse link
G CCNA2 cyclin A2 decreases expression EXP
ISO
Cocaine results in decreased expression of CCNA2 mRNA CTD PMID:18593214 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCND1 cyclin D1 affects expression ISO Cocaine affects the expression of CCND1 mRNA CTD PMID:20187946 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND3 cyclin D3 affects expression ISO Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCNL1 cyclin L1 increases expression ISO Cocaine results in increased expression of CCNL1 mRNA CTD PMID:16076954 NCBI chr 3:157,143,121...157,160,180
Ensembl chr 3:157,146,508...157,160,760
JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases response to substance
affects expression
ISO CCR2 results in increased susceptibility to Cocaine
Cocaine affects the expression of CCR2 mRNA
CTD PMID:20187946 PMID:20354174 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,744...46,360,940
Ensembl chr 3:46,353,744...46,360,940
JBrowse link
G CCR5 C-C motif chemokine receptor 5 increases expression EXP Cocaine results in increased expression of CCR5 protein CTD PMID:16204638 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CCSER1 coiled-coil serine rich protein 1 affects response to substance EXP CCSER1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 4:90,127,394...91,605,295
Ensembl chr 4:90,127,535...91,601,913
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 affects expression ISO Cocaine affects the expression of CCT2 mRNA CTD PMID:20187946 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
JBrowse link
G CCZ1 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated decreases expression EXP Cocaine results in decreased expression of CCZ1 mRNA CTD PMID:12629581 NCBI chr 7:5,898,733...5,926,550
Ensembl chr 7:5,898,725...5,926,550
JBrowse link
G CD180 CD180 molecule decreases expression ISO Cocaine results in decreased expression of CD180 mRNA CTD PMID:27899881 NCBI chr 5:67,179,613...67,196,799
Ensembl chr 5:67,179,613...67,196,799
JBrowse link
G CD276 CD276 molecule affects expression ISO Cocaine affects the expression of CD276 mRNA CTD PMID:20187946 NCBI chr15:73,683,966...73,714,518
Ensembl chr15:73,683,966...73,714,514
JBrowse link
G CD4 CD4 molecule multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA CTD PMID:18355967 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799
JBrowse link
G CD44 CD44 molecule (Indian blood group) decreases expression EXP Cocaine results in decreased expression of CD44 mRNA CTD PMID:18000554 NCBI chr11:35,139,168...35,232,402
Ensembl chr11:35,138,882...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD47 CD47 molecule affects expression ISO Cocaine affects the expression of CD47 mRNA CTD PMID:20187946 NCBI chr 3:108,043,091...108,094,200
Ensembl chr 3:108,043,091...108,091,862
JBrowse link
G CD74 CD74 molecule affects expression ISO Cocaine affects the expression of CD74 mRNA CTD PMID:20187946 NCBI chr 5:150,400,041...150,412,936
Ensembl chr 5:150,400,041...150,412,929
JBrowse link
G CD81 CD81 molecule increases response to substance
increases expression
affects response to substance
EXP
ISO
CD81 protein results in increased susceptibility to Cocaine
Cocaine results in increased expression of CD81 mRNA
CD81 protein affects the susceptibility to Cocaine
CTD PMID:11178868 PMID:12113778 PMID:15715673 NCBI chr11:2,376,180...2,397,402
Ensembl chr11:2,376,177...2,397,419
Ensembl chr11:2,376,177...2,397,419
JBrowse link
G CD93 CD93 molecule decreases expression ISO Cocaine results in decreased expression of CD93 mRNA CTD PMID:17898221 NCBI chr20:23,076,554...23,086,830
Ensembl chr20:23,079,360...23,086,324
JBrowse link
G CDC14B cell division cycle 14B decreases expression ISO Cocaine results in decreased expression of CDC14B mRNA CTD PMID:17898221 NCBI chr 9:96,492,743...96,619,843
Ensembl chr 9:96,490,241...96,619,843
JBrowse link
G CDC25A cell division cycle 25A increases expression ISO Cocaine results in increased expression of CDC25A mRNA CTD PMID:17898221 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
JBrowse link
G CDH1 cadherin 1 decreases expression EXP Cocaine results in decreased expression of CDH1 mRNA CTD PMID:12629581 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,541
JBrowse link
G CDH16 cadherin 16 affects expression ISO Cocaine affects the expression of CDH16 mRNA CTD PMID:20187946 NCBI chr16:66,908,122...66,918,885
Ensembl chr16:66,908,122...66,918,917
JBrowse link
G CDH17 cadherin 17 decreases expression EXP Cocaine results in decreased expression of CDH17 mRNA CTD PMID:12629581 NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
JBrowse link
G CDK18 cyclin dependent kinase 18 affects expression ISO Cocaine affects the expression of CDK18 mRNA CTD PMID:20187946 NCBI chr 1:205,504,593...205,532,793
Ensembl chr 1:205,504,595...205,532,793
Ensembl chr 1:205,504,595...205,532,793
JBrowse link
G CDK4 cyclin dependent kinase 4 affects expression ISO Cocaine affects the expression of CDK4 mRNA CTD PMID:18355967 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDK5 cyclin dependent kinase 5 affects expression
increases expression
decreases expression
ISO Cocaine affects the expression of CDK5 mRNA; Cocaine affects the expression of CDK5 protein
Cocaine results in increased expression of CDK5 mRNA; Cocaine results in increased expression of CDK5 protein
Cocaine results in decreased expression of CDK5 protein
CTD PMID:11268215 PMID:12787079 PMID:16263094 PMID:17339080 PMID:17680995 PMID:20187946 NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897
JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 multiple interactions
increases expression
decreases expression
ISO CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK3 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
Cocaine results in increased expression of CDK5R1 mRNA; Cocaine results in increased expression of CDK5R1 protein
Cocaine results in decreased expression of CDK5R1 protein
CTD PMID:11268215 PMID:15665076 PMID:16263094 NCBI chr17:32,485,028...32,491,256
Ensembl chr17:32,486,993...32,491,253
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CEACAM4 CEA cell adhesion molecule 4 affects expression ISO Cocaine affects the expression of CEACAM3 mRNA CTD PMID:20187946 NCBI chr19:41,616,986...41,627,087
Ensembl chr19:41,618,971...41,627,074
JBrowse link
G CEL carboxyl ester lipase increases expression ISO Cocaine results in increased expression of CEL mRNA CTD PMID:27899881 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,978...133,071,863
Ensembl chr 9:133,061,978...133,071,863
JBrowse link
G CES1 carboxylesterase 1 multiple interactions
increases hydrolysis
affects binding
EXP CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol]; Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin]
CES1 protein results in increased hydrolysis of Cocaine
Cocaine binds to CES1 protein
CTD PMID:8930175 PMID:9311626 PMID:12679808 PMID:12773168 PMID:25445008 NCBI chr16:55,802,851...55,833,127
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G CES2 carboxylesterase 2 multiple interactions
decreases expression
increases hydrolysis
EXP Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of Heroin]
Cocaine results in decreased expression of CES2 mRNA
CES2 protein results in increased hydrolysis of Cocaine
CTD PMID:8930175 PMID:9169443 PMID:12629581 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096
JBrowse link
G CFH complement factor H decreases expression ISO Cocaine results in decreased expression of CFH mRNA CTD PMID:17898221 NCBI chr 1:196,652,033...196,747,504
Ensembl chr 1:196,652,043...196,747,504
Ensembl chr 1:196,652,043...196,747,504
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator affects expression ISO Cocaine affects the expression of CFLAR mRNA CTD PMID:15681117 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CHFR checkpoint with forkhead and ring finger domains affects expression ISO Cocaine affects the expression of CHFR mRNA CTD PMID:20187946 NCBI chr12:132,832,356...132,887,618
Ensembl chr12:132,822,187...132,956,304
JBrowse link
G CHN1 chimerin 1 affects expression ISO Cocaine affects the expression of CHN1 mRNA CTD PMID:20187946 NCBI chr 2:174,798,809...175,005,381
Ensembl chr 2:174,799,313...175,005,381
Ensembl chr 2:174,799,313...175,005,381
JBrowse link
G CHRM4 cholinergic receptor muscarinic 4 affects expression ISO Cocaine affects the expression of CHRM4 mRNA CTD PMID:20187946 NCBI chr11:46,383,789...46,391,776
Ensembl chr11:46,385,098...46,386,608
JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 decreases response to substance ISO CHRM5 mutant form results in decreased susceptibility to Cocaine CTD PMID:20393457 NCBI chr15:33,968,497...34,067,458
Ensembl chr15:33,968,497...34,067,458
Ensembl chr15:33,968,497...34,067,458
JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr20:63,343,223...63,375,471
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit decreases response to substance EXP CHRNA5 gene polymorphism results in decreased susceptibility to Cocaine CTD PMID:18519132 NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269
JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit multiple interactions
increases response to substance
ISO Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CHRNB2 protein results in increased susceptibility to Cocaine
CTD PMID:10336510 PMID:11282258 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit increases expression ISO Cocaine results in increased expression of CHRNE mRNA CTD PMID:27899881 NCBI chr17:4,897,771...4,905,019
Ensembl chr17:4,897,771...4,934,438
JBrowse link
G CHTF8 chromosome transmission fidelity factor 8 decreases expression ISO Cocaine results in decreased expression of CHTF8 mRNA CTD PMID:17898221 NCBI chr16:69,118,010...69,132,588
Ensembl chr16:69,118,010...69,132,578
Ensembl chr16:69,118,010...69,132,578
JBrowse link
G CHURC1 churchill domain containing 1 decreases expression EXP Cocaine results in decreased expression of CHURC1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr14:64,914,455...64,935,368
Ensembl chr14:64,914,361...64,944,591
JBrowse link
G CIAO1 cytosolic iron-sulfur assembly component 1 affects expression ISO Cocaine affects the expression of CIAO1 mRNA CTD PMID:20187946 NCBI chr 2:96,266,159...96,274,173
Ensembl chr 2:96,266,159...96,274,173
JBrowse link
G CIDEA cell death inducing DFFA like effector a affects expression ISO Cocaine affects the expression of CIDEA mRNA CTD PMID:15681117 NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
JBrowse link
G CIDEB cell death inducing DFFA like effector b affects expression ISO Cocaine affects the expression of CIDEB mRNA CTD PMID:15681117 NCBI chr14:24,305,096...24,311,435
Ensembl chr14:24,305,096...24,311,430
JBrowse link
G CISD1 CDGSH iron sulfur domain 1 increases expression ISO Cocaine results in increased expression of CISD1 protein CTD PMID:25100957 NCBI chr10:58,269,162...58,289,586
Ensembl chr10:58,269,162...58,289,586
JBrowse link
G CISD2 CDGSH iron sulfur domain 2 increases expression ISO Cocaine results in increased expression of CISD2 mRNA CTD PMID:17898221 NCBI chr 4:102,868,992...102,892,807
Ensembl chr 4:102,868,974...102,892,807
JBrowse link
G CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 decreases expression ISO Cocaine results in decreased expression of CITED4 mRNA CTD PMID:27899881 NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363
JBrowse link
G CKB creatine kinase B multiple interactions EXP Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr14:103,519,667...103,522,833
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CKM creatine kinase, M-type multiple interactions EXP Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875
JBrowse link
G CKMT1B creatine kinase, mitochondrial 1B affects expression ISO Cocaine affects the expression of CKMT1 mRNA CTD PMID:20187946 NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901
JBrowse link
G CLCN7 chloride voltage-gated channel 7 affects expression ISO Cocaine affects the expression of CLCN7 mRNA CTD PMID:20187946 NCBI chr16:1,444,935...1,475,028
Ensembl chr16:1,444,934...1,475,084
JBrowse link
G CLDN11 claudin 11 decreases expression EXP Cocaine results in decreased expression of CLDN11 mRNA CTD PMID:18357522 NCBI chr 3:170,418,868...170,434,691
Ensembl chr 3:170,418,865...170,454,733
Ensembl chr 3:170,418,865...170,454,733
JBrowse link
G CLEC4F C-type lectin domain family 4 member F affects expression ISO Cocaine affects the expression of CLEC4F mRNA CTD PMID:20187946 NCBI chr 2:70,808,643...70,825,235
Ensembl chr 2:70,808,643...70,820,599
JBrowse link
G CLIC1 chloride intracellular channel 1 decreases expression EXP Cocaine results in decreased expression of CLIC1 mRNA CTD PMID:18000554 NCBI chr 6:31,730,581...31,737,318
Ensembl chr 6:31,730,581...31,739,763
JBrowse link
G CLIP1 CAP-Gly domain containing linker protein 1 increases expression EXP Cocaine results in increased expression of CLIP1 mRNA CTD PMID:18000554 NCBI chr12:122,271,432...122,422,956
Ensembl chr12:122,271,432...122,422,632
JBrowse link
G CLK1 CDC like kinase 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of CLK1 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]
CTD PMID:18355967 NCBI chr 2:200,853,009...200,864,658
Ensembl chr 2:200,853,009...200,864,744
JBrowse link
G CLK4 CDC like kinase 4 increases expression ISO Cocaine results in increased expression of CLK4 mRNA CTD PMID:20056891 NCBI chr 5:178,602,664...178,627,050
Ensembl chr 5:178,602,664...178,630,615
JBrowse link
G CLOCK clock circadian regulator increases expression ISO Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 NCBI chr 4:55,427,903...55,547,138
Ensembl chr 4:55,427,903...55,546,909
JBrowse link
G CLTB clathrin light chain B decreases expression EXP Cocaine results in decreased expression of CLTB mRNA CTD PMID:12629581 PMID:15009677 NCBI chr 5:176,392,455...176,416,569
Ensembl chr 5:176,392,455...176,416,569
Ensembl chr 5:176,392,455...176,416,569
JBrowse link
G CLYBL citramalyl-CoA lyase increases expression ISO Cocaine results in increased expression of CLYBL protein CTD PMID:25100957 NCBI chr13:99,606,664...99,909,444
Ensembl chr13:99,606,669...99,897,134
JBrowse link
G CNBD2 cyclic nucleotide binding domain containing 2 increases expression ISO Cocaine results in increased expression of CNBD2 mRNA CTD PMID:17898221 NCBI chr20:35,954,561...36,030,700
Ensembl chr20:35,954,564...36,030,700
JBrowse link
G CNKSR2 connector enhancer of kinase suppressor of Ras 2 increases expression EXP Cocaine results in increased expression of CNKSR2 mRNA CTD PMID:15009677 NCBI chr  X:21,374,418...21,654,689
Ensembl chr  X:21,372,801...21,654,695
JBrowse link
G CNR1 cannabinoid receptor 1 affects response to substance
increases activity
decreases response to substance
multiple interactions
EXP
ISO
CNR1 gene polymorphism affects the susceptibility to Cocaine; CNR1 gene SNP affects the susceptibility to Cocaine; CNR1 polymorphism affects the susceptibility to Cocaine
Cocaine results in increased activity of CNR1 protein
CNR1 mutant form results in decreased susceptibility to Cocaine
CNR1 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:9106242 PMID:16314880 PMID:17596442 PMID:19052543 PMID:20554863 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,359
JBrowse link
G CNR2 cannabinoid receptor 2 increases expression ISO Cocaine results in increased expression of CNR2 mRNA CTD PMID:18286196 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G COBLL1 cordon-bleu WH2 repeat protein like 1 increases expression ISO Cocaine results in increased expression of COBLL1 mRNA CTD PMID:27506785 NCBI chr 2:164,657,931...164,842,076
Ensembl chr 2:164,653,624...164,843,679
JBrowse link
G COIL coilin affects expression ISO Cocaine affects the expression of COIL mRNA CTD PMID:20187946 NCBI chr17:56,938,199...56,961,050
Ensembl chr17:56,938,199...56,961,050
JBrowse link
G COL15A1 collagen type XV alpha 1 chain affects expression ISO Cocaine affects the expression of COL15A1 mRNA CTD PMID:20187946 NCBI chr 9:98,943,392...99,070,787
Ensembl chr 9:98,943,179...99,070,792
JBrowse link
G COL1A1 collagen type I alpha 1 chain increases expression ISO Cocaine results in increased expression of COL1A1 mRNA CTD PMID:9455993 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G COL21A1 collagen type XXI alpha 1 chain affects response to substance EXP COL21A1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 6:56,056,590...56,394,128
Ensembl chr 6:56,056,590...56,394,094
JBrowse link
G COL3A1 collagen type III alpha 1 chain increases expression ISO Cocaine results in increased expression of COL3A1 mRNA CTD PMID:9455993 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COQ6 coenzyme Q6, monooxygenase affects expression ISO Cocaine affects the expression of COQ6 mRNA CTD PMID:20187946 NCBI chr14:73,949,926...73,963,670
Ensembl chr14:73,949,926...73,963,670
JBrowse link
G CORO7 coronin 7 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA CTD PMID:18355967 NCBI chr16:4,354,542...4,416,596
Ensembl chr16:4,354,542...4,425,705
JBrowse link
G COX20 cytochrome c oxidase assembly factor COX20 decreases expression ISO Cocaine results in decreased expression of COX20 mRNA CTD PMID:17898221 NCBI chr 1:244,835,306...244,845,063
Ensembl chr 1:244,835,616...244,845,057
JBrowse link
G COX5A cytochrome c oxidase subunit 5A affects expression ISO Cocaine affects the expression of COX5A mRNA CTD PMID:20187946 NCBI chr15:74,919,791...74,938,073
Ensembl chr15:74,919,791...74,938,083
JBrowse link
G COX6A1 cytochrome c oxidase subunit 6A1 affects expression
increases expression
ISO Cocaine affects the expression of COX6A1 mRNA
Cocaine results in increased expression of COX6A1 protein
CTD PMID:20187946 PMID:25100957 NCBI chr12:120,438,113...120,440,730
Ensembl chr12:120,438,090...120,440,737
JBrowse link
G COX6C cytochrome c oxidase subunit 6C decreases expression EXP Cocaine results in decreased expression of COX6C mRNA CTD PMID:12629581 NCBI chr 8:99,877,865...99,893,707
Ensembl chr 8:99,873,200...99,893,707
JBrowse link
G COX7B cytochrome c oxidase subunit 7B affects expression ISO Cocaine affects the expression of COX7B mRNA CTD PMID:20187946 NCBI chr  X:77,899,468...77,907,376
Ensembl chr  X:77,899,440...77,907,376
JBrowse link
G COX8A cytochrome c oxidase subunit 8A affects expression ISO Cocaine affects the expression of COX8A mRNA CTD PMID:20187946 NCBI chr11:63,974,620...63,976,543
Ensembl chr11:63,974,620...63,976,543
JBrowse link
G CPLX1 complexin 1 affects expression ISO Cocaine affects the expression of CPLX1 mRNA CTD PMID:20187946 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129
JBrowse link
G CPNE8 copine 8 increases expression ISO Cocaine results in increased expression of CPNE8 mRNA CTD PMID:17898221 NCBI chr12:38,652,200...38,906,269
Ensembl chr12:38,646,822...38,907,430
JBrowse link
G CREB1 cAMP responsive element binding protein 1 affects expression
increases phosphorylation
multiple interactions
affects phosphorylation
increases expression
ISO Cocaine affects the expression of CREB1 mRNA
Cocaine results in increased phosphorylation of CREB1 protein
CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of CREB1 protein]; RPS6KA3 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
Cocaine affects the phosphorylation of CREB1 protein
Betaxolol affects the reaction [Cocaine affects the phosphorylation of CREB1 protein]; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of CREB1 protein; U 0126 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
CTD PMID:12595601 PMID:15470197 PMID:15665076 PMID:16219028 PMID:16339038 PMID:16710312 PMID:18596687 PMID:20187946 PMID:20810894 PMID:24358339 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CREBBP CREB binding protein increases expression ISO Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CREBRF CREB3 regulatory factor increases expression ISO Cocaine results in increased expression of CREBRF mRNA CTD PMID:17898221 NCBI chr 5:173,056,349...173,139,284
Ensembl chr 5:173,056,352...173,139,284
JBrowse link
G CREM cAMP responsive element modulator affects expression
increases expression
ISO Cocaine affects the expression of CREM mRNA
Cocaine results in increased expression of CREM mRNA
CTD PMID:18355967 PMID:27899881 NCBI chr10:35,126,830...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CRH corticotropin releasing hormone multiple interactions
affects expression
ISO Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA]; Cocaine affects the reaction [CRH protein affects the secretion of Excitatory Amino Acid Agents]; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
Cocaine affects the expression of CRH mRNA; Cocaine affects the expression of CRH protein
CTD PMID:7796157 PMID:11597771 PMID:12782395 PMID:15930388 PMID:18596687 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CRHBP corticotropin releasing hormone binding protein increases expression ISO Cocaine results in increased expression of CRHBP mRNA CTD PMID:27899881 NCBI chr 5:76,952,855...76,981,143
Ensembl chr 5:76,953,045...76,981,158
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 increases expression ISO Cocaine results in increased expression of CRHR1 protein CTD PMID:17079348 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G CRIP2 cysteine rich protein 2 affects expression ISO Cocaine affects the expression of CRIP2 mRNA CTD PMID:20187946 NCBI chr14:105,472,945...105,480,170
Ensembl chr14:105,472,962...105,480,170
Ensembl chr14:105,472,962...105,480,170
JBrowse link
G CRISPLD1 cysteine rich secretory protein LCCL domain containing 1 decreases expression ISO Cocaine results in decreased expression of CRISPLD1 mRNA CTD PMID:27899881 NCBI chr 8:74,984,505...75,034,558
Ensembl chr 8:74,984,505...75,034,558
JBrowse link
G CRP C-reactive protein increases expression EXP Cocaine results in increased expression of CRP protein CTD PMID:11988210 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CRTAC1 cartilage acidic protein 1 affects expression ISO Cocaine affects the expression of CRTAC1 mRNA CTD PMID:20187946 NCBI chr10:97,854,711...98,030,621
Ensembl chr10:97,865,000...98,030,828
JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 multiple interactions ISO [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein CTD PMID:20613834 NCBI chr19:18,683,621...18,782,333
Ensembl chr19:18,683,678...18,782,333
JBrowse link
G CRY1 cryptochrome circadian regulator 1 decreases expression ISO Cocaine results in decreased expression of CRY1 mRNA CTD PMID:15994025 NCBI chr12:106,991,364...107,093,872
Ensembl chr12:106,991,364...107,093,549
JBrowse link
G CRY2 cryptochrome circadian regulator 2 decreases expression ISO Cocaine results in decreased expression of CRY2 mRNA CTD PMID:15994025 NCBI chr11:45,847,118...45,883,244
Ensembl chr11:45,847,118...45,883,248
JBrowse link
G CRYAB crystallin alpha B decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of CRYAB mRNA
Cocaine results in increased expression of CRYAB mRNA
CTD PMID:15009677 PMID:27899881 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CRYBB2 crystallin beta B2 decreases expression EXP Cocaine results in decreased expression of CRYBB2 mRNA CTD PMID:15009677 NCBI chr22:25,211,660...25,231,869
Ensembl chr22:25,212,564...25,231,870
JBrowse link
G CSAD cysteine sulfinic acid decarboxylase affects expression
decreases expression
ISO Cocaine affects the expression of CSAD mRNA
Cocaine results in decreased expression of CSAD protein
CTD PMID:20187946 PMID:25100957 NCBI chr12:53,157,663...53,181,663
Ensembl chr12:53,157,663...53,180,909
Ensembl chr12:53,157,663...53,180,909
JBrowse link
G CSF2RA colony stimulating factor 2 receptor subunit alpha decreases expression ISO Cocaine results in decreased expression of CSF2RA mRNA CTD PMID:17898221 NCBI chr  X:1,268,814...1,325,218
NCBI chr  Y:1,268,814...1,325,218
Ensembl chr  X:1,268,800...1,310,381
JBrowse link
G CSN3 casein kappa affects expression ISO Cocaine affects the expression of CSN3 mRNA CTD PMID:20187946 NCBI chr 4:70,238,381...70,251,432
Ensembl chr 4:70,242,588...70,251,428
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 decreases expression ISO Cocaine results in decreased expression of CSNK2A1 mRNA CTD PMID:12117546 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835
JBrowse link
G CSPG5 chondroitin sulfate proteoglycan 5 affects expression ISO Cocaine affects the expression of CSPG5 mRNA; Cocaine affects the expression of CSPG5 protein CTD PMID:12358776 NCBI chr 3:47,562,238...47,580,240
Ensembl chr 3:47,562,238...47,580,792
JBrowse link
G CSRP2 cysteine and glycine rich protein 2 decreases expression EXP Cocaine results in decreased expression of CSRP2 mRNA CTD PMID:18000554 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 affects expression ISO Cocaine affects the expression of CTDNEP1 mRNA CTD PMID:20187946 NCBI chr17:7,243,591...7,251,978
Ensembl chr17:7,243,591...7,252,491
JBrowse link
G CTNNB1 catenin beta 1 affects expression
multiple interactions
ISO Cocaine affects the expression of CTNNB1 mRNA
Cocaine deficiency promotes the reaction [SMARCA4 protein binds to CTNNB1 promoter]
CTD PMID:20187946 PMID:27422367 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTNNBIP1 catenin beta interacting protein 1 decreases expression EXP Cocaine results in decreased expression of CTNNBIP1 mRNA CTD PMID:18000554 NCBI chr 1:9,848,276...9,910,322
Ensembl chr 1:9,848,276...9,910,336
JBrowse link
G CTNND2 catenin delta 2 decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of CTNND2 mRNA
Cocaine results in increased expression of CTNND2 mRNA
CTD PMID:12629581 PMID:16076954 NCBI chr 5:10,971,836...11,904,446
Ensembl chr 5:10,971,836...11,904,446
JBrowse link
G CTRL chymotrypsin like affects expression
increases expression
ISO Cocaine affects the expression of CTRL mRNA
Cocaine results in increased expression of CTRL mRNA
CTD PMID:20187946 PMID:27899881 NCBI chr16:67,929,574...67,931,862
Ensembl chr16:67,927,640...67,932,365
JBrowse link
G CTSB cathepsin B affects expression
multiple interactions
increases expression
ISO Cocaine affects the expression of CTSB mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]
CTD PMID:15681117 PMID:18355967 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,448
Ensembl chr 8:11,842,524...11,869,448
JBrowse link
G CTSD cathepsin D affects expression
increases expression
ISO Cocaine affects the expression of CTSD mRNA
Cocaine results in increased expression of CTSD protein
CTD PMID:15681117 PMID:25100957 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CUEDC1 CUE domain containing 1 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA] CTD PMID:17988634 NCBI chr17:57,861,243...57,955,412
Ensembl chr17:57,861,243...57,955,412
JBrowse link
G CUL4B cullin 4B increases expression EXP Cocaine results in increased expression of CUL4B mRNA CTD PMID:15009677 NCBI chr  X:120,523,858...120,575,532
Ensembl chr  X:120,524,612...120,575,794
Ensembl chr  X:120,524,612...120,575,794
Ensembl chr  X:120,524,612...120,575,794
JBrowse link
G CWF19L2 CWF19 like cell cycle control factor 2 increases expression ISO Cocaine results in increased expression of CWF19L2 mRNA CTD PMID:17898221 NCBI chr11:107,326,345...107,457,846
Ensembl chr11:107,326,345...107,457,844
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 increases expression ISO Cocaine results in increased expression of CX3CL1 mRNA CTD PMID:16076954 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases secretion EXP Cocaine results in increased secretion of CXCL10 protein CTD PMID:10065903 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases secretion EXP Cocaine results in increased secretion of CXCL8 protein CTD PMID:10065903 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 decreases expression ISO Cocaine results in decreased expression of CXCL9 mRNA CTD PMID:17898221 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression EXP Cocaine results in increased expression of CXCR4 protein CTD PMID:16204638 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G CXXC5 CXXC finger protein 5 affects expression ISO Cocaine affects the expression of CXXC5 mRNA CTD PMID:20187946 NCBI chr 5:139,647,299...139,683,882
Ensembl chr 5:139,647,299...139,683,882
JBrowse link
G CYBA cytochrome b-245 alpha chain increases expression ISO Cocaine results in increased expression of CYBA protein CTD PMID:18952886 NCBI chr16:88,643,289...88,651,079
Ensembl chr16:88,643,289...88,651,054
JBrowse link
G CYBB cytochrome b-245 beta chain increases expression
increases response to substance
ISO Cocaine results in increased expression of CYBB protein
CYBB results in increased susceptibility to Cocaine
CTD PMID:18952886 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,059...37,813,461
JBrowse link
G CYC1 cytochrome c1 decreases expression EXP Cocaine results in decreased expression of CYC1 mRNA CTD PMID:12629581 NCBI chr 8:144,095,076...144,097,525
Ensembl chr 8:144,095,039...144,097,525
JBrowse link
G CYCS cytochrome c, somatic affects expression
multiple interactions
ISO Cocaine affects the expression of CYCS mRNA
Minocycline inhibits the reaction [Cocaine results in increased secretion of CYCS protein]
CTD PMID:15681117 PMID:21424555 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYGB cytoglobin decreases expression ISO Cocaine results in decreased expression of CYGB protein CTD PMID:25100957 NCBI chr17:76,527,356...76,557,692
Ensembl chr17:76,527,356...76,551,175
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 decreases expression ISO Cocaine results in decreased expression of CYP19A1 mRNA CTD PMID:27899881 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression
ISO Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein] CTD PMID:11856816 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 affects expression ISO Cocaine affects the expression of CYP26A1 mRNA CTD PMID:20187946 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 decreases response to substance ISO CYP26B1 protein results in decreased susceptibility to Cocaine CTD PMID:27899881 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,148,038
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 decreases expression EXP Cocaine results in decreased expression of CYP2C8 mRNA; Cocaine results in decreased expression of CYP2C8 protein CTD PMID:16188404 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 decreases expression EXP Cocaine results in decreased expression of CYP2C9 mRNA; Cocaine results in decreased expression of CYP2C9 protein CTD PMID:16188404 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 increases expression
multiple interactions
ISO Cocaine results in increased expression of CYP2J2 protein
Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]
CTD PMID:11856816 NCBI chr 1:59,893,308...59,926,773
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 decreases expression EXP Cocaine results in decreased expression of CYP51 mRNA CTD PMID:12629581 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,112,153...92,134,803
JBrowse link
G DAB2IP DAB2 interacting protein decreases expression ISO Cocaine results in decreased expression of DAB2IP mRNA CTD PMID:17898221 NCBI chr 9:121,566,883...121,785,530
Ensembl chr 9:121,567,057...121,785,530
JBrowse link
G DAZAP1 DAZ associated protein 1 affects expression ISO Cocaine affects the expression of DAZAP1 mRNA CTD PMID:20187946 NCBI chr19:1,407,586...1,435,684
Ensembl chr19:1,407,569...1,435,687
JBrowse link
G DBH dopamine beta-hydroxylase increases response to substance
decreases response to substance
EXP
ISO
DBH gene polymorphism results in increased susceptibility to Cocaine
DBH gene mutant form results in decreased susceptibility to Cocaine
CTD PMID:10673769 PMID:12555232 PMID:18083142 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DBN1 drebrin 1 multiple interactions ISO Cocaine deficiency promotes the reaction [SMARCA4 protein binds to DBN1 promoter] CTD PMID:27422367 NCBI chr 5:177,456,610...177,480,368
Ensembl chr 5:177,456,608...177,474,401
JBrowse link
G DCAF8 DDB1 and CUL4 associated factor 8 affects expression ISO Cocaine affects the expression of DCAF8 mRNA CTD PMID:20187946 NCBI chr 1:160,215,720...160,262,549
Ensembl chr 1:160,215,715...160,262,549
Ensembl chr 1:160,215,715...160,262,549
JBrowse link
G DDIT3 DNA damage inducible transcript 3 affects expression
increases expression
ISO Cocaine affects the expression of DDIT3 mRNA
Cocaine results in increased expression of DDIT3 mRNA
CTD PMID:15681117 PMID:20187946 PMID:23644055 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 decreases expression ISO Cocaine results in decreased expression of DDR2 mRNA CTD PMID:17898221 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405
JBrowse link
G DDX41 DEAD-box helicase 41 decreases expression EXP Cocaine results in decreased expression of DDX41 mRNA CTD PMID:18000554 NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961
JBrowse link
G DDX50 DExD-box helicase 50 affects expression ISO Cocaine affects the expression of DDX50 mRNA CTD PMID:20187946 NCBI chr10:68,898,817...68,956,312
Ensembl chr10:68,901,286...68,946,847
JBrowse link
G DDX6 DEAD-box helicase 6 increases expression ISO Cocaine results in increased expression of DDX6 mRNA CTD PMID:17898221 NCBI chr11:118,747,763...118,791,696
Ensembl chr11:118,747,763...118,791,164
JBrowse link
G DEAF1 DEAF1 transcription factor decreases expression EXP Cocaine results in decreased expression of DEAF1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr11:644,220...707,083
Ensembl chr11:644,233...706,715
JBrowse link
G DHH desert hedgehog signaling molecule affects expression ISO Cocaine affects the expression of DHH mRNA CTD PMID:20187946 NCBI chr12:49,086,656...49,094,801
Ensembl chr12:49,086,656...49,094,801
JBrowse link
G DHX30 DExH-box helicase 30 affects expression ISO Cocaine affects the expression of DHX30 mRNA CTD PMID:20187946 NCBI chr 3:47,802,990...47,850,193
Ensembl chr 3:47,802,909...47,850,195
JBrowse link
G DIPK1B divergent protein kinase domain 1B affects expression ISO Cocaine affects the expression of DIPK1B mRNA CTD PMID:20187946 NCBI chr 9:136,712,572...136,724,742
Ensembl chr 9:136,712,572...136,724,742
JBrowse link
G DLG2 discs large MAGUK scaffold protein 2 increases expression ISO Cocaine results in increased expression of DLG2 protein CTD PMID:25100957 NCBI chr11:83,455,009...85,628,535
Ensembl chr11:83,455,012...85,627,922
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 affects expression
increases expression
multiple interactions
decreases response to substance
decreases expression
ISO Cocaine affects the expression of DLG4 mRNA; Cocaine affects the expression of DLG4 protein
Cocaine results in increased expression of DLG4 protein
ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]
DLG4 protein results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of DLG4 mRNA
CTD PMID:14980210 PMID:19629758 PMID:20187946 PMID:20534846 PMID:20600170 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,189,890...7,219,841
Ensembl chr17:7,189,890...7,219,841
Ensembl chr17:7,189,890...7,219,841
JBrowse link
G DLK2 delta like non-canonical Notch ligand 2 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DLK2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]
CTD PMID:18355967 NCBI chr 6:43,450,352...43,456,632
Ensembl chr 6:43,450,352...43,456,632
JBrowse link
G DNAH8 dynein axonemal heavy chain 8 affects response to substance EXP DNAH8 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 6:38,715,311...39,030,798
Ensembl chr 6:38,715,311...39,030,792
JBrowse link
G DNM1 dynamin 1 affects expression ISO Cocaine affects the expression of DNM1 mRNA CTD PMID:20187946 NCBI chr 9:128,203,379...128,255,244
Ensembl chr 9:128,191,655...128,255,248
JBrowse link
G DNM1L dynamin 1 like multiple interactions
increases phosphorylation
ISO [Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]
Cocaine results in increased phosphorylation of DNM1L protein
CTD PMID:30158054 PMID:31494168 NCBI chr12:32,679,296...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G DNM2 dynamin 2 affects expression ISO Cocaine affects the expression of DNM2 mRNA CTD PMID:20187946 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,079...10,833,488
JBrowse link
G DNM3 dynamin 3 affects expression ISO Cocaine affects the expression of DNM3 mRNA CTD PMID:20187946 NCBI chr 1:171,841,495...172,418,466
Ensembl chr 1:171,841,498...172,418,466
JBrowse link
G DNMBP dynamin binding protein decreases expression ISO Cocaine results in decreased expression of DNMBP mRNA CTD PMID:17898221 NCBI chr10:99,875,571...100,009,948
Ensembl chr10:99,875,577...100,009,947
JBrowse link
G DNMT3B DNA methyltransferase 3 beta decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DNMT3B mRNA; Cocaine results in decreased expression of DNMT3B protein
Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA]; Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein]
CTD PMID:22438930 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,356
JBrowse link
G DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression EXP Cocaine results in decreased expression of DNPH1 mRNA CTD PMID:15009677 PMID:16710320 NCBI chr 6:43,225,629...43,229,481
Ensembl chr 6:43,225,629...43,229,484
Ensembl chr 6:43,225,629...43,229,484
JBrowse link
G DPF2 double PHD fingers 2 increases expression EXP Cocaine results in increased expression of DPF2 mRNA CTD PMID:18000554 NCBI chr11:65,333,840...65,354,262
Ensembl chr11:65,333,852...65,354,262
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 multiple interactions ISO [Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of DPYSL2 protein CTD PMID:19457111 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G DPYSL3 dihydropyrimidinase like 3 affects expression ISO Cocaine affects the expression of DPYSL3 mRNA CTD PMID:20187946 NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068
JBrowse link
G DRD1 dopamine receptor D1 multiple interactions
decreases expression
affects response to substance
affects expression
increases response to substance
decreases response to substance
EXP
ISO
1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein]; Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
Cocaine results in decreased expression of DRD1 protein
DRD1 protein affects the susceptibility to Cocaine
Cocaine affects the expression of DRD1 protein
DRD1 results in increased susceptibility to Cocaine
DRD1 gene mutant form results in decreased susceptibility to Cocaine
Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of PDYN protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of SYT7 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
[anhydroecgonine methyl ester co-treated with Cocaine] results in decreased expression of DRD1 protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]
CTD PMID:2213551 PMID:8001143 PMID:11421588 PMID:11602327 PMID:15049517 PMID:15056714 PMID:16674926 PMID:17161392 PMID:20435100 PMID:20456009 PMID:20956312 PMID:27129946 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 decreases expression
affects response to substance
increases activity
increases expression
multiple interactions
affects expression
decreases response to substance
increases response to substance
EXP
ISO
Cocaine results in decreased expression of DRD2 mRNA; Cocaine results in decreased expression of DRD2 protein
DRD2 protein affects the susceptibility to Cocaine
Cocaine results in increased activity of DRD2 protein
Cocaine results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein
Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]; Methadone affects the reaction [Cocaine affects the expression of DRD2 mRNA]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]
Cocaine affects the expression of DRD2; Cocaine affects the expression of DRD2 mRNA; Cocaine affects the expression of DRD2 protein
DRD2 protein results in decreased susceptibility to Cocaine
PDYN protein affects the reaction [Cocaine affects the expression of DRD2 protein]
DRD2 results in increased susceptibility to Cocaine
DRD2 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the reaction [Raclopride binds to DRD2]
CTD PMID:2213551 PMID:9892293 PMID:11126397 PMID:11602327 PMID:11790512 PMID:11923462 PMID:12892653 PMID:15010698 PMID:15042275 PMID:15049517 PMID:17161392 PMID:17532787 PMID:17544385 PMID:17671965 PMID:18000554 PMID:18305460 PMID:18990547 PMID:19046384 PMID:19723785 PMID:20435100 PMID:20729865 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 decreases expression
decreases response to substance
increases expression
increases activity
affects expression
affects activity
multiple interactions
affects response to substance
EXP
ISO
Cocaine results in decreased expression of DRD3 protein
DRD3 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of DRD3 mRNA
Cocaine results in increased activity of DRD3 protein
Cocaine affects the expression of DRD3 protein
Cocaine affects the activity of DRD3 protein
DRD3 protein results in decreased susceptibility to Cocaine
7-hydroxy-2-N,N-dipropylaminotetralin inhibits the reaction [Cocaine affects the activity of DRD3 protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]
DRD3 affects the susceptibility to Cocaine
[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine; [3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol co-treated with Cocaine] affects the localization of DRD3 protein; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of PDYN protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of SYT7 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; DRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of PDYN protein]; SB 277011 inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine]
CTD PMID:10523822 PMID:10943692 PMID:11120399 PMID:12099907 PMID:15056714 PMID:15100700 PMID:16026479 PMID:18566292 PMID:19046384 PMID:19217379 PMID:19723785 PMID:20435100 PMID:20456009 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DRD4 dopamine receptor D4 increases response to substance
affects expression
EXP
ISO
DRD4 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD4 mRNA
CTD PMID:17671965 PMID:20187946 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G DRD5 dopamine receptor D5 affects expression ISO Cocaine affects the expression of DRD5 mRNA CTD PMID:20187946 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009
JBrowse link
G DRP2 dystrophin related protein 2 affects expression EXP Cocaine affects the expression of DRP2 protein CTD PMID:19393250 NCBI chr  X:101,219,786...101,264,502
Ensembl chr  X:101,219,769...101,264,497
JBrowse link
G DSP desmoplakin increases expression EXP Cocaine results in increased expression of DSP protein CTD PMID:17075605 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,617...7,586,714
JBrowse link
G DUSP1 dual specificity phosphatase 1 affects expression
increases phosphorylation
ISO Cocaine affects the expression of DUSP1 mRNA
Cocaine results in increased phosphorylation of DUSP1 protein
CTD PMID:18822274 PMID:20187946 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP5 dual specificity phosphatase 5 affects expression
increases expression
ISO Cocaine affects the expression of CPG21 mRNA
Cocaine results in increased expression of DUSP5 mRNA
CTD PMID:20187946 PMID:27899881 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
JBrowse link
G DUSP8 dual specificity phosphatase 8 multiple interactions
increases expression
ISO 5,7-Dihydroxytryptamine inhibits the reaction [Cocaine results in increased expression of DUSP8 mRNA] CTD PMID:9813294 NCBI chr11:1,554,051...1,572,839
Ensembl chr11:1,554,051...1,572,271
JBrowse link
G DVL1 dishevelled segment polarity protein 1 affects expression ISO Cocaine affects the expression of DVL1 mRNA CTD PMID:20187946 NCBI chr 1:1,335,278...1,349,418
Ensembl chr 1:1,335,276...1,349,418
JBrowse link
G DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 decreases expression EXP Cocaine results in decreased expression of DYNC1I1 mRNA CTD PMID:12629581 NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322
JBrowse link
G DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 increases expression ISO Cocaine results in increased expression of DYNC1LI2 protein CTD PMID:25100957 NCBI chr16:66,720,893...66,751,609
Ensembl chr16:66,720,893...66,751,609
JBrowse link
G DYNLL1 dynein light chain LC8-type 1 affects expression ISO Cocaine affects the expression of DYNLL1 mRNA CTD PMID:20187946 NCBI chr12:120,469,842...120,498,493
Ensembl chr12:120,469,850...120,498,493
JBrowse link
G ECI2 enoyl-CoA delta isomerase 2 affects expression ISO Cocaine affects the expression of PECI mRNA CTD PMID:20187946 NCBI chr 6:4,115,693...4,135,591
Ensembl chr 6:4,115,689...4,135,597
Ensembl chr 6:4,115,689...4,135,597
JBrowse link
G EDN1 endothelin 1 increases expression ISO
EXP
Cocaine results in increased expression of EDN1 protein CTD PMID:9714087 PMID:11948058 PMID:17420087 PMID:18813882 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDNRA endothelin receptor type A increases expression EXP
ISO
Cocaine results in increased expression of EDNRA protein CTD PMID:17420087 PMID:18813882 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G EDNRB endothelin receptor type B affects expression ISO Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 affects expression ISO Cocaine affects the expression of EEF1A1 mRNA CTD PMID:20187946 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,515,750...73,523,797
Ensembl chr 6:73,515,750...73,523,797
JBrowse link
G EEF1A2 eukaryotic translation elongation factor 1 alpha 2 affects expression ISO Cocaine affects the expression of EEF1A2 mRNA CTD PMID:20187946 NCBI chr20:63,488,014...63,499,083
Ensembl chr20:63,488,013...63,499,239
Ensembl chr20:63,488,013...63,499,239
JBrowse link
G EEF1G eukaryotic translation elongation factor 1 gamma decreases expression EXP Cocaine results in decreased expression of EEF1G mRNA CTD PMID:15009677 NCBI chr11:62,559,596...62,573,891
Ensembl chr11:62,559,596...62,574,086
JBrowse link
G EFCAB3 EF-hand calcium binding domain 3 affects expression
decreases expression
ISO Cocaine affects the expression of EFCAB3 mRNA
Cocaine results in decreased expression of EFCAB3 mRNA
CTD PMID:17898221 PMID:20187946 NCBI chr17:62,370,218...62,416,480
Ensembl chr17:62,343,941...62,416,480
Ensembl chr17:62,343,941...62,416,480
JBrowse link
G EFNA1 ephrin A1 affects expression ISO Cocaine affects the expression of EFNA1 mRNA CTD PMID:15691709 NCBI chr 1:155,127,876...155,134,899
Ensembl chr 1:155,127,876...155,134,899
JBrowse link
G EFNA2 ephrin A2 affects expression ISO Cocaine affects the expression of EFNA2 mRNA CTD PMID:15691709 NCBI chr19:1,282,817...1,301,431
Ensembl chr19:1,285,873...1,301,431
JBrowse link
G EFNA3 ephrin A3 affects expression ISO Cocaine affects the expression of EFNA3 mRNA CTD PMID:15691709 NCBI chr 1:155,078,837...155,087,538
Ensembl chr 1:155,078,837...155,087,538
JBrowse link
G EFNA4 ephrin A4 affects expression ISO Cocaine affects the expression of EFNA4 mRNA CTD PMID:15691709 NCBI chr 1:155,063,740...155,069,553
Ensembl chr 1:155,063,737...155,069,553
JBrowse link
G EFNA5 ephrin A5 increases expression ISO Cocaine results in increased expression of EFNA5 mRNA CTD PMID:15691709 NCBI chr 5:107,376,889...107,670,937
Ensembl chr 5:107,376,889...107,670,937
JBrowse link
G EFNB1 ephrin B1 increases expression ISO Cocaine results in increased expression of EFNB1 mRNA CTD PMID:15691709 PMID:17898221 NCBI chr  X:68,829,021...68,842,160
Ensembl chr  X:68,829,021...68,842,160
JBrowse link
G EFNB2 ephrin B2 increases expression ISO Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662
JBrowse link
G EFNB3 ephrin B3 increases expression ISO Cocaine results in increased expression of EFNB3 mRNA CTD PMID:15691709 NCBI chr17:7,705,202...7,711,372
Ensembl chr17:7,705,202...7,711,372
JBrowse link
G EFTUD2 elongation factor Tu GTP binding domain containing 2 affects expression ISO Cocaine affects the expression of EFTUD2 mRNA CTD PMID:20187946 NCBI chr17:44,849,948...44,899,445
Ensembl chr17:44,849,948...44,899,445
JBrowse link
G EGFR epidermal growth factor receptor decreases expression EXP Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 affects expression
increases expression
multiple interactions
increases response to substance
ISO Cocaine affects the expression of EGR1 mRNA
Cocaine results in increased expression of EGR1 protein
NPPC protein inhibits the reaction [Cocaine results in increased expression of EGR1 mRNA]
Cocaine results in increased expression of EGR1 mRNA; Cocaine results in increased expression of EGR1 protein
EGR1 results in increased susceptibility to Cocaine
[Cocaine co-treated with Caffeine] results in increased expression of EGR1 mRNA; Cocaine promotes the reaction [Caffeine results in increased expression of EGR1 mRNA]
CTD PMID:1347779 PMID:7905595 PMID:9890435 PMID:10971643 PMID:11860464 PMID:16339038 PMID:16459018 PMID:16738229 PMID:17851536 PMID:18311559 PMID:18355967 PMID:20187946 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EGR2 early growth response 2 increases expression
affects expression
ISO Cocaine results in increased expression of EGR2 mRNA
Cocaine affects the expression of EGR2 mRNA
CTD PMID:20056891 PMID:20187946 PMID:27899881 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,919,900
JBrowse link
G EGR3 early growth response 3 affects expression
multiple interactions
increases expression
ISO Cocaine affects the expression of EGR3 mRNA
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to EGR3 promoter]
Cocaine results in increased expression of EGR3 mRNA
CTD PMID:16459018 PMID:20187946 PMID:30158054 NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
JBrowse link
G EGR4 early growth response 4 increases expression ISO Cocaine results in increased expression of EGR4 mRNA CTD PMID:27899881 NCBI chr 2:73,290,929...73,293,548
Ensembl chr 2:73,290,929...73,293,701
JBrowse link
G EHD2 EH domain containing 2 decreases expression ISO Cocaine results in decreased expression of EHD2 mRNA CTD PMID:17898221 NCBI chr19:47,713,422...47,743,134
Ensembl chr19:47,713,422...47,743,134
JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 decreases expression ISO Cocaine results in decreased expression of EHMT1 mRNA CTD PMID:20056891 NCBI chr 9:137,619,001...137,836,127
Ensembl chr 9:137,618,992...137,870,016
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 multiple interactions
decreases response to substance
decreases expression
ISO Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TGFBR1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TNFRSF25 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of USP9X mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of WNK3 mRNA]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]
EHMT2 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of EHMT2 mRNA; Cocaine results in decreased expression of EHMT2 protein
CTD PMID:20056891 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,687
JBrowse link
G EIF1AX eukaryotic translation initiation factor 1A X-linked increases expression ISO Cocaine results in increased expression of EIF1AY mRNA CTD PMID:17898221 NCBI chr  X:20,124,525...20,141,838
Ensembl chr  X:20,124,525...20,141,838
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
ISO Cocaine results in increased expression of EIF2AK3 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]
CTD PMID:17303341 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,151...67,386,516
Ensembl chr14:67,360,151...67,386,516
JBrowse link
G EIF3A eukaryotic translation initiation factor 3 subunit A increases expression ISO Cocaine results in increased expression of EIF3A mRNA CTD PMID:17898221 NCBI chr10:119,033,670...119,080,817
Ensembl chr10:119,033,670...119,080,823
JBrowse link
G EIF3B eukaryotic translation initiation factor 3 subunit B affects expression ISO Cocaine affects the expression of EIF3B mRNA CTD PMID:20187946 NCBI chr 7:2,354,086...2,380,745
Ensembl chr 7:2,354,086...2,380,745
JBrowse link
G EIF3C eukaryotic translation initiation factor 3 subunit C increases expression ISO Cocaine results in increased expression of EIF3C mRNA CTD PMID:17898221 NCBI chr16:28,688,558...28,735,730
Ensembl chr16:28,688,558...28,735,730
Ensembl chr16:28,688,558...28,735,730
JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E affects expression ISO Cocaine affects the expression of EIF3E mRNA CTD PMID:20187946 NCBI chr 8:108,201,216...108,248,734
Ensembl chr 8:108,201,216...108,435,333
Ensembl chr 8:108,201,216...108,435,333
JBrowse link
G EIF4B eukaryotic translation initiation factor 4B multiple interactions
increases expression
ISO FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA] CTD PMID:18355967 NCBI chr12:53,006,456...53,042,215
Ensembl chr12:53,006,282...53,042,215
Ensembl chr12:53,006,282...53,042,215
JBrowse link
G EIF5A eukaryotic translation initiation factor 5A decreases expression
affects expression
increases expression
EXP
ISO
Cocaine results in decreased expression of EIF5A mRNA
Cocaine affects the expression of EIF5A mRNA
Cocaine results in increased expression of EIF5A mRNA
CTD PMID:15009677 PMID:16710320 PMID:20187946 NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463
JBrowse link
G EIF5B eukaryotic translation initiation factor 5B increases expression ISO Cocaine results in increased expression of EIF5B mRNA CTD PMID:17898221 NCBI chr 2:99,337,389...99,401,326
Ensembl chr 2:99,337,371...99,401,326
JBrowse link
G ELANE elastase, neutrophil expressed multiple interactions EXP [Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein] CTD PMID:18438818 NCBI chr19:850,997...856,250
Ensembl chr19:851,014...856,247
JBrowse link
G ELMO1 engulfment and cell motility 1 multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA] CTD PMID:20056891 NCBI chr 7:36,852,906...37,449,326
Ensembl chr 7:36,854,361...37,449,249
JBrowse link
G EMC9 ER membrane protein complex subunit 9 affects expression ISO Cocaine affects the expression of EMC9 mRNA CTD PMID:20187946 NCBI chr14:24,138,959...24,142,602
Ensembl chr14:24,138,959...24,141,591
JBrowse link
G ENAH ENAH actin regulator increases expression ISO Cocaine results in increased expression of ENAH mRNA CTD PMID:17898221 NCBI chr 1:225,486,829...225,660,046
Ensembl chr 1:225,486,835...225,653,142
JBrowse link
G ENC1 ectodermal-neural cortex 1 increases expression ISO Cocaine results in increased expression of ENC1 mRNA CTD PMID:17898221 NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
JBrowse link
G ENHO energy homeostasis associated decreases expression EXP Cocaine results in decreased expression of ENHO mRNA CTD PMID:16710320 NCBI chr 9:34,521,043...34,522,990
Ensembl chr 9:34,521,043...34,522,990
JBrowse link
G ENO2 enolase 2 decreases expression
increases expression
EXP Cocaine results in decreased expression of ENO2 mRNA
Cocaine results in increased expression of ENO2 protein
CTD PMID:12629581 PMID:17075605 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
JBrowse link
G ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 increases expression EXP Cocaine results in increased expression of ENPP5 mRNA CTD PMID:15009677 NCBI chr 6:46,159,182...46,171,006
Ensembl chr 6:46,159,185...46,170,980
JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression ISO Cocaine results in decreased expression of ENTPD2 protein CTD PMID:25100957 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061
JBrowse link
G ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA CTD PMID:18355967 NCBI chr 3:40,387,182...40,428,744
Ensembl chr 3:40,387,184...40,428,744
JBrowse link
G EPHA1 EPH receptor A1 affects expression ISO Cocaine affects the expression of EPHA1 mRNA CTD PMID:15691709 NCBI chr 7:143,390,813...143,408,865
Ensembl chr 7:143,390,289...143,408,856
JBrowse link
G EPHA2 EPH receptor A2 affects expression ISO Cocaine affects the expression of EPHA2 mRNA CTD PMID:15691709 NCBI chr 1:16,124,337...16,156,104
Ensembl chr 1:16,124,337...16,156,069
JBrowse link
G EPHA3 EPH receptor A3 affects expression ISO Cocaine affects the expression of EPHA3 mRNA CTD PMID:15691709 NCBI chr 3:89,107,621...89,482,134
Ensembl chr 3:89,107,621...89,482,134
JBrowse link
G EPHA4 EPH receptor A4 affects expression
increases expression
ISO Cocaine affects the expression of EPHA4 mRNA
Cocaine results in increased expression of EPHA4 mRNA
CTD PMID:15691709 PMID:17898221 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202
JBrowse link
G EPHA5 EPH receptor A5 affects expression ISO Cocaine affects the expression of EPHA5 mRNA CTD PMID:15691709 NCBI chr 4:65,319,567...65,670,489
Ensembl chr 4:65,319,563...65,670,495
JBrowse link
G EPHA7 EPH receptor A7 affects expression ISO Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 NCBI chr 6:93,240,020...93,419,584
Ensembl chr 6:93,240,020...93,419,559
JBrowse link
G EPHA8 EPH receptor A8 affects expression ISO Cocaine affects the expression of EPHA8 mRNA CTD PMID:15691709 NCBI chr 1:22,563,489...22,603,595
Ensembl chr 1:22,563,489...22,603,595
JBrowse link
G EPHB1 EPH receptor B1 increases expression ISO Cocaine results in increased expression of EPHB1 protein
Cocaine results in increased expression of EPHB1 mRNA
CTD PMID:11146119 PMID:15691709 NCBI chr 3:134,595,264...135,260,467
Ensembl chr 3:134,597,801...135,260,467
JBrowse link
G EPHB2 EPH receptor B2 increases expression ISO Cocaine results in increased expression of EPHB2 mRNA CTD PMID:15691709 NCBI chr 1:22,710,770...22,921,500
Ensembl chr 1:22,710,839...22,921,500
JBrowse link
G EPHB3 EPH receptor B3 affects expression ISO Cocaine affects the expression of EPHB3 mRNA CTD PMID:15691709 NCBI chr 3:184,561,785...184,582,408
Ensembl chr 3:184,561,785...184,582,408
JBrowse link
G EPHB4 EPH receptor B4 decreases expression
affects expression
EXP
ISO
Cocaine results in decreased expression of EPHB4 mRNA
Cocaine affects the expression of EPHB4 mRNA
CTD PMID:15691709 PMID:18000554 NCBI chr 7:100,802,565...100,827,523
Ensembl chr 7:100,802,565...100,827,523
JBrowse link
G EPHB6 EPH receptor B6 affects expression ISO Cocaine affects the expression of EPHB6 mRNA CTD PMID:15691709 NCBI chr 7:142,854,639...142,871,093
Ensembl chr 7:142,855,061...142,871,094
JBrowse link
G ERBIN erbb2 interacting protein multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA] CTD PMID:17988634 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,926,475...66,082,549
Ensembl chr 5:65,926,475...66,082,549
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
ISO 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,142...64,130,819
JBrowse link
G ESS2 ess-2 splicing factor homolog decreases expression ISO Cocaine results in decreased expression of ESS2 mRNA CTD PMID:17898221 NCBI chr22:19,130,279...19,144,726
Ensembl chr22:19,130,279...19,144,684
JBrowse link
G ETF1 eukaryotic translation termination factor 1 affects expression ISO Cocaine affects the expression of ETF1 mRNA CTD PMID:20187946 NCBI chr 5:138,506,095...138,543,236
Ensembl chr 5:138,506,095...138,543,236
JBrowse link
G ETFA electron transfer flavoprotein subunit alpha affects expression ISO Cocaine affects the expression of ETFA mRNA CTD PMID:20187946 NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,215,353...76,311,472
JBrowse link
G EXOC2 exocyst complex component 2 increases expression ISO Cocaine results in increased expression of EXOC2 protein CTD PMID:25100957 NCBI chr 6:485,154...693,141
Ensembl chr 6:485,154...693,139
JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 increases expression EXP Cocaine results in increased expression of EYA1 mRNA CTD PMID:15009677 NCBI chr 8:71,197,433...71,548,104
Ensembl chr 8:71,197,433...71,592,025
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 affects expression ISO Cocaine affects the expression of EYA2 mRNA CTD PMID:20187946 NCBI chr20:46,894,843...47,188,844
Ensembl chr20:46,894,624...47,188,844
JBrowse link
G EZR ezrin decreases expression EXP Cocaine results in decreased expression of EZR mRNA CTD PMID:20948987 NCBI chr 6:158,765,744...158,819,368
Ensembl chr 6:158,765,741...158,819,368
JBrowse link
G FADD Fas associated via death domain affects expression
multiple interactions
decreases expression
ISO Cocaine affects the expression of FADD mRNA
Raclopride affects the reaction [Cocaine affects the expression of FADD protein]
Cocaine results in decreased expression of FADD protein modified form
CTD PMID:18580876 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,163...70,207,390
Ensembl chr11:70,203,163...70,207,390
JBrowse link
G FAHD1 fumarylacetoacetate hydrolase domain containing 1 increases expression ISO Cocaine results in increased expression of FAHD1 protein CTD PMID:25100957 NCBI chr16:1,827,224...1,840,207
Ensembl chr16:1,826,941...1,840,207
JBrowse link
G FAHD2A fumarylacetoacetate hydrolase domain containing 2A affects expression EXP Cocaine affects the expression of FAHD2A protein CTD PMID:19393250 NCBI chr 2:95,402,672...95,416,702
Ensembl chr 2:95,402,708...95,416,616
JBrowse link
G FAIM Fas apoptotic inhibitory molecule affects expression ISO Cocaine affects the expression of FAIM mRNA CTD PMID:15681117 NCBI chr 3:138,608,099...138,633,376
Ensembl chr 3:138,608,606...138,633,376
JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 increases expression ISO Cocaine results in increased expression of FAIM2 mRNA CTD PMID:16076954 NCBI chr12:49,866,896...49,903,900
Ensembl chr12:49,866,896...49,904,217
JBrowse link
G FAM153A family with sequence similarity 153 member A increases expression EXP Cocaine results in increased expression of FAM153A mRNA CTD PMID:16710320 NCBI chr 5:177,694,247...177,783,518
Ensembl chr 5:177,707,981...177,783,398
JBrowse link
G FAM155A family with sequence similarity 155 member A increases expression ISO Cocaine results in increased expression of FAM155A mRNA CTD PMID:17898221 NCBI chr13:107,163,510...107,867,496
Ensembl chr13:107,163,510...107,867,496
JBrowse link
G FAM184B family with sequence similarity 184 member B decreases expression ISO Cocaine results in decreased expression of FAM184B mRNA CTD PMID:27899881 NCBI chr 4:17,629,306...17,781,621
Ensembl chr 4:17,629,306...17,781,621
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase affects expression ISO Cocaine affects the expression of FAM20C mRNA CTD PMID:20187946 NCBI chr 7:192,571...260,772
Ensembl chr 7:192,571...260,772
JBrowse link
G FAM78B family with sequence similarity 78 member B decreases expression ISO Cocaine results in decreased expression of FAM78B mRNA CTD PMID:17898221 NCBI chr 1:166,055,918...166,167,001
Ensembl chr 1:166,057,426...166,167,001
Ensembl chr 1:166,057,426...166,167,001
JBrowse link
G FAS Fas cell surface death receptor increases expression EXP Cocaine results in increased expression of FAS mRNA CTD PMID:16710320 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FBXL3 F-box and leucine rich repeat protein 3 increases expression ISO Cocaine results in increased expression of FBXL3 mRNA CTD PMID:17898221 NCBI chr13:76,992,597...77,027,164
Ensembl chr13:76,992,598...77,027,195
JBrowse link
G FBXO46 F-box protein 46 affects expression ISO Cocaine affects the expression of FBXO46 mRNA CTD PMID:20187946 NCBI chr19:45,710,629...45,733,177
Ensembl chr19:45,710,629...45,730,896
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb decreases expression ISO Cocaine results in decreased expression of FCGR2B mRNA CTD PMID:27899881 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,147...161,678,654
JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 increases expression EXP Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,304
JBrowse link
G FEV FEV transcription factor, ETS family member decreases expression ISO Cocaine results in decreased expression of FEV mRNA CTD PMID:17898221 NCBI chr 2:218,981,087...218,985,184
Ensembl chr 2:218,981,087...218,985,184
Ensembl chr 2:218,981,087...218,985,184
JBrowse link
G FGD5 FYVE, RhoGEF and PH domain containing 5 increases expression ISO Cocaine results in increased expression of FGD5 mRNA CTD PMID:17898221 NCBI chr 3:14,818,962...14,934,571
Ensembl chr 3:14,810,853...14,934,571
JBrowse link
G FGF12 fibroblast growth factor 12 affects expression ISO Cocaine affects the expression of FGF12 mRNA CTD PMID:20187946 NCBI chr 3:192,139,390...192,727,541
Ensembl chr 3:192,139,395...192,767,764
JBrowse link
G FGF2 fibroblast growth factor 2 decreases expression EXP Cocaine results in decreased expression of FGF2 mRNA CTD PMID:12629581 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 increases expression ISO Cocaine results in increased expression of FGFR1 mRNA CTD PMID:16076954 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FH fumarate hydratase affects expression EXP Cocaine affects the expression of FH1 protein CTD PMID:19393250 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,603...241,519,761
Ensembl chr 1:241,497,603...241,519,761
JBrowse link
G FIS1 fission, mitochondrial 1 increases expression ISO Cocaine results in increased expression of FIS1 mRNA CTD PMID:31494168 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B affects expression ISO Cocaine affects the expression of FKBP1B mRNA CTD PMID:20187946 NCBI chr 2:24,033,205...24,067,743
Ensembl chr 2:24,049,701...24,063,681
JBrowse link
G FKBPL FKBP prolyl isomerase like affects expression ISO Cocaine affects the expression of FKBPL mRNA CTD PMID:20187946 NCBI chr 6:32,128,707...32,130,288
Ensembl chr 6:32,128,707...32,130,288
JBrowse link
G FLRT3 fibronectin leucine rich transmembrane protein 3 increases expression EXP Cocaine results in increased expression of FLRT3 mRNA CTD PMID:18000554 NCBI chr20:14,322,985...14,337,847
Ensembl chr20:14,322,985...14,337,614
JBrowse link
G FLYWCH1 FLYWCH-type zinc finger 1 decreases expression ISO Cocaine results in decreased expression of FLYWCH1 mRNA CTD PMID:17898221 NCBI chr16:2,911,873...2,951,208
Ensembl chr16:2,911,931...2,951,208
Ensembl chr16:2,911,931...2,951,208
JBrowse link
G FMR1 FMRP translational regulator 1 decreases expression ISO Cocaine results in decreased expression of FMR1 mRNA CTD PMID:24810662 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,951...147,951,125
Ensembl chr  X:147,911,951...147,951,125
JBrowse link
G FNDC1 fibronectin type III domain containing 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA CTD PMID:18355967 NCBI chr 6:159,169,400...159,272,108
Ensembl chr 6:159,169,400...159,272,108
JBrowse link
G FNDC5 fibronectin type III domain containing 5 affects expression ISO Cocaine affects the expression of FNDC5 mRNA CTD PMID:20187946 NCBI chr 1:32,862,268...32,872,484
Ensembl chr 1:32,862,268...32,872,482
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects expression
increases phosphorylation
decreases response to substance
increases activity
decreases expression
EXP
ISO
[Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]
Cocaine results in increased expression of FOS mRNA; Cocaine results in increased expression of FOS protein
Cocaine affects the expression of FOS mRNA; Cocaine affects the expression of FOS protein
Cocaine results in increased phosphorylation of FOS protein
[Morphine co-treated with Cocaine] affects the expression of FOS; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Alcohols promotes the reaction [Cocaine results in increased expression of FOS protein]; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; Chloral Hydrate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Cocaine promotes the reaction [Cocaine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [Ethanol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; ecopipam inhibits the reaction [Cocaine results in increased expression of FOS protein]; Ethanol promotes the reaction [Cocaine results in increased expression of FOS protein]; Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; Urethane inhibits the reaction [Cocaine results in increased expression of FOS protein]; volinanserin inhibits the reaction [Cocaine results in increased expression of FOS protein]
FOS protein mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased activity of FOS protein
Cocaine results in decreased expression of FOS protein
[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of PDYN protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of SYT7 protein; [Cocaine co-treated with Caffeine] results in increased expression of FOS mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of NEXN mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PBX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PER1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PINX1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PKNOX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PLPP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PRKCZ mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SYT9 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of THRA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of LARGE1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of NRIP3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SATB2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SORCS3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of TENM4 mRNA; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [Caffeine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of MAPK11 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NCALD mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NPTXR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NRN1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of PRKCA mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SATB1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SEZ6L mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KCNT1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LIN7B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of MEPCE mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NIT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NOS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PBX3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PPP1R7 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PRPF18 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PTPRV mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SBSN mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYNE1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of TSPOAP1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ZFPM1 mRNA]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOS protein]; N-methyl-3-(bis(4'-fluorophenyl)methoxy)tropane inhibits the reaction [Cocaine results in increased expression of FOS protein]; NTRK2 protein affects the reaction [Cocaine affects the expression of FOS protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in increased expression of FOS protein]; RPS6KA3 affects the reaction [Cocaine results in increased phosphorylation of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased activity of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS protein]
CTD PMID:1498673 PMID:2118661 PMID:7905595 PMID:10415707 PMID:10521585 PMID:10632609 PMID:10814832 PMID:10904129 PMID:10943692 PMID:10971643 PMID:11160452 PMID:11172061 PMID:11403691 PMID:11421588 PMID:11716816 PMID:11739600 PMID:11860464 PMID:11882344 PMID:12112414 PMID:12122080 PMID:12128156 PMID:12379259 PMID:12419516 PMID:12581847 PMID:12670717 PMID:12699766 PMID:12786985 PMID:12821175 PMID:14644470 PMID:14741756 PMID:15056714 PMID:15219685 PMID:15254092 PMID:15295023 PMID:15665076 PMID:15814102 PMID:16179556 PMID:16263220 PMID:16300424 PMID:16339038 PMID:16395306 PMID:16459018 PMID:16710312 PMID:16930414 PMID:16962079 PMID:17276011 PMID:17596442 PMID:17851536 PMID:18164822 PMID:18311559 PMID:18355967 PMID:18396266 PMID:18479823 PMID:18822274 PMID:18991842 PMID:19169671 PMID:19606084 PMID:19620976 PMID:20187946 PMID:20633205 PMID:20947769 PMID:25933444 PMID:27899881 PMID:31059705 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
affects expression
EXP
ISO
Cocaine results in increased expression of FOSB protein
DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
Cocaine results in increased expression of FOSB mRNA; Cocaine results in increased expression of FOSB protein; Cocaine results in increased expression of FOSB protein alternative form
Cocaine affects the expression of FOSB mRNA; Cocaine affects the expression of FOSB protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein; [JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine; Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; PPP1R1B gene mutant form inhibits the reaction [Cocaine results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]
CTD PMID:10103106 PMID:11391778 PMID:11739600 PMID:12417638 PMID:15056714 PMID:15814102 PMID:15926929 PMID:16263220 PMID:16674926 PMID:16710312 PMID:17898221 PMID:18293355 PMID:18355967 PMID:18822274 PMID:20056891 PMID:20633205 PMID:27899881 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit affects expression
decreases expression
ISO
EXP
Cocaine affects the expression of FOSL1 mRNA
Cocaine results in decreased expression of FOSL1 mRNA
CTD PMID:12117546 PMID:12629581 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit multiple interactions
decreases expression
EXP
ISO
Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein]
Cocaine results in decreased expression of FOSL2 protein
CTD PMID:15056714 PMID:15814102 NCBI chr 2:28,392,855...28,417,317
Ensembl chr 2:28,392,448...28,417,317
JBrowse link
G FOXC2 forkhead box C2 decreases expression ISO Cocaine results in decreased expression of FOXC2 mRNA CTD PMID:17898221 NCBI chr16:86,566,829...86,569,728
Ensembl chr16:86,566,829...86,569,728
JBrowse link
G FOXO1 forkhead box O1 decreases expression ISO Cocaine results in decreased expression of FOXO1 mRNA CTD PMID:17898221 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G FRAS1 Fraser extracellular matrix complex subunit 1 increases expression ISO Cocaine results in increased expression of FRAS1 mRNA CTD PMID:17898221 NCBI chr 4:78,057,323...78,544,269
Ensembl chr 4:78,057,323...78,544,269
JBrowse link
G FREM2 FRAS1 related extracellular matrix 2 decreases expression ISO Cocaine results in decreased expression of FREM2 mRNA CTD PMID:27899881 NCBI chr13:38,687,041...38,887,131
Ensembl chr13:38,687,077...38,887,131
JBrowse link
G FRMD5 FERM domain containing 5 decreases expression ISO Cocaine results in decreased expression of FRMD5 mRNA CTD PMID:17898221 NCBI chr15:43,870,764...44,195,271
Ensembl chr15:43,870,761...44,195,271
JBrowse link
G FRS3 fibroblast growth factor receptor substrate 3 affects expression ISO Cocaine affects the expression of FRS3 mRNA CTD PMID:20187946 NCBI chr 6:41,770,176...41,779,900
Ensembl chr 6:41,770,176...41,786,542
JBrowse link
G FUBP1 far upstream element binding protein 1 affects expression ISO Cocaine affects the expression of FUBP1 mRNA CTD PMID:20187946 NCBI chr 1:77,944,055...77,979,435
Ensembl chr 1:77,944,055...77,979,110
JBrowse link
G FUT8 fucosyltransferase 8 affects expression ISO Cocaine affects the expression of FUT8 mRNA CTD PMID:20187946 NCBI chr14:65,410,592...65,744,122
Ensembl chr14:65,410,592...65,744,121
JBrowse link
G FZD6 frizzled class receptor 6 affects expression ISO Cocaine affects the expression of FZD6 mRNA CTD PMID:20187946 NCBI chr 8:103,298,494...103,332,866
Ensembl chr 8:103,298,433...103,332,866
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases expression ISO Cocaine results in increased expression of G6PD protein CTD PMID:25100957 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 affects expression
increases expression
decreases expression
ISO Cocaine affects the expression of GABBR1 mRNA
Cocaine results in increased expression of GABBR1 mRNA
Cocaine results in decreased expression of GABBR1 mRNA
CTD PMID:11793422 PMID:16076954 PMID:20187946 NCBI chr 6:29,602,230...29,633,183
Ensembl chr 6:29,555,629...29,633,976
JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 decreases phosphorylation ISO Cocaine results in decreased phosphorylation of GABBR2 protein CTD PMID:12716959 NCBI chr 9:98,288,104...98,708,935
Ensembl chr 9:98,288,109...98,708,935
JBrowse link
G GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 affects expression
multiple interactions
ISO
EXP
Cocaine affects the expression of GABRA1 protein
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:20826313 PMID:23266428 PMID:32209479 NCBI chr 5:161,847,191...161,899,971
Ensembl chr 5:161,847,063...161,899,981
JBrowse link
G GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Cocaine results in increased expression of GABRB1 mRNA CTD PMID:17898221 NCBI chr 4:46,993,560...47,438,409
Ensembl chr 4:46,993,723...47,426,447
JBrowse link
G GABRB2 gamma-aminobutyric acid type A receptor subunit beta2 multiple interactions EXP
ISO
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD PMID:23266428 PMID:32209479 NCBI chr 5:161,288,436...161,548,404
Ensembl chr 5:161,288,429...161,549,044
JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 affects expression
multiple interactions
ISO Cocaine affects the expression of GABRB3 mRNA
Cocaine affects the phosphorylation of and affects the expression of GABRB3 protein
CTD PMID:20187946 PMID:20826313 NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,546...26,939,539
JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 multiple interactions EXP
ISO
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD PMID:23266428 PMID:32209479 NCBI chr 5:162,067,465...162,155,539
Ensembl chr 5:162,000,057...162,162,977
JBrowse link
G GAD1 glutamate decarboxylase 1 decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of GAD1 mRNA
Cocaine results in increased expression of GAD1 protein
CTD PMID:12629581 PMID:15295023 PMID:18611417 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
JBrowse link
G GAL galanin and GMAP prepropeptide multiple interactions ISO GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:19099295 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
JBrowse link
G GALK1 galactokinase 1 affects expression ISO Cocaine affects the expression of GALK1 mRNA CTD PMID:20187946 NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
JBrowse link
G GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression ISO Cocaine results in increased expression of GALNT1 mRNA CTD PMID:17898221 NCBI chr18:35,580,922...35,711,834
Ensembl chr18:35,581,117...35,711,834
JBrowse link
G GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 affects expression ISO Cocaine affects the expression of GALNT16 mRNA CTD PMID:20187946 NCBI chr14:69,259,546...69,379,904
Ensembl chr14:69,259,277...69,357,033
JBrowse link
G GAP43 growth associated protein 43 decreases expression EXP Cocaine results in decreased expression of GAP43 mRNA CTD PMID:12629581 NCBI chr 3:115,623,510...115,721,485
Ensembl chr 3:115,623,324...115,721,490
Ensembl chr 3:115,623,324...115,721,490
JBrowse link
G GAS2 growth arrest specific 2 affects expression ISO Cocaine affects the expression of GAS2 mRNA CTD PMID:15681117 NCBI chr11:22,627,758...22,885,930
Ensembl chr11:22,625,509...22,813,055
JBrowse link
G GCC1 GRIP and coiled-coil domain containing 1 increases expression EXP Cocaine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 7:127,580,628...127,585,596
Ensembl chr 7:127,580,628...127,593,611
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression
multiple interactions
ISO Cocaine results in increased expression of GCLC mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]
CTD PMID:30393195 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit affects expression
multiple interactions
increases expression
ISO Cocaine affects the expression of GCLM mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]
CTD PMID:20187946 PMID:30393195 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GDAP1 ganglioside induced differentiation associated protein 1 increases expression ISO Cocaine results in increased expression of GDAP1 protein CTD PMID:25100957 NCBI chr 8:74,350,403...74,488,872
Ensembl chr 8:74,320,613...74,518,007
Ensembl chr 8:74,320,613...74,518,007
JBrowse link
G GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 decreases expression ISO Cocaine results in decreased expression of GDAP1L1 protein CTD PMID:25100957 NCBI chr20:44,247,099...44,280,947
Ensembl chr20:44,247,099...44,280,947
Ensembl chr20:44,247,099...44,280,947
JBrowse link
G GDNF glial cell derived neurotrophic factor decreases expression ISO Cocaine results in decreased expression of GDNF mRNA CTD PMID:14622243 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle increases expression EXP Cocaine results in increased expression of GEM mRNA CTD PMID:15009677 NCBI chr 8:94,249,249...94,262,345
Ensembl chr 8:94,249,253...94,262,350
JBrowse link
G GFAP glial fibrillary acidic protein increases expression
decreases expression
affects expression
EXP
ISO
Cocaine results in increased expression of GFAP protein
Cocaine results in decreased expression of GFAP protein
Cocaine affects the expression of GFAP mRNA; Cocaine affects the expression of GFAP protein
CTD PMID:11391778 PMID:11882367 PMID:12670315 PMID:15814102 PMID:20187946 NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GFRA2 GDNF family receptor alpha 2 affects expression ISO Cocaine affects the expression of GFRA2 mRNA CTD PMID:12358776 NCBI chr 8:21,690,398...21,789,296
Ensembl chr 8:21,690,398...21,812,357
JBrowse link
G GH1 growth hormone 1 multiple interactions EXP
ISO
Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein]; Cocaine inhibits the reaction [Sodium Oxybate results in increased expression of GH1 protein]
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
CTD PMID:9413023 PMID:10657535 PMID:15099682 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GID8 GID complex subunit 8 homolog affects expression ISO Cocaine affects the expression of GID8 mRNA CTD PMID:20187946 NCBI chr20:62,938,147...62,948,475
Ensembl chr20:62,938,147...62,948,475
JBrowse link
G GIMAP1 GTPase, IMAP family member 1 affects expression ISO Cocaine affects the expression of GIMAP1 mRNA CTD PMID:20187946 NCBI chr 7:150,716,613...150,724,284
Ensembl chr 7:150,716,606...150,724,284
JBrowse link
G GIMAP5 GTPase, IMAP family member 5 affects expression ISO Cocaine affects the expression of GIMAP5 mRNA CTD PMID:20187946 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033
JBrowse link
G GINS3 GINS complex subunit 3 decreases expression ISO Cocaine results in decreased expression of GINS3 mRNA CTD PMID:27899881 NCBI chr16:58,392,471...58,406,147
Ensembl chr16:58,295,080...58,406,144
Ensembl chr16:58,295,080...58,406,144
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 affects expression ISO Cocaine affects the expression of GIPC1 mRNA CTD PMID:20187946 NCBI chr19:14,477,761...14,496,133
Ensembl chr19:14,477,760...14,496,149
JBrowse link
G GJA5 gap junction protein alpha 5 increases expression ISO Cocaine results in increased expression of GJA5 mRNA CTD PMID:27899881 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GJB1 gap junction protein beta 1 affects expression ISO Cocaine affects the expression of GJB1 mRNA; Cocaine affects the expression of GJB1 protein CTD PMID:10510198 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G GJB2 gap junction protein beta 2 decreases expression EXP Cocaine results in decreased expression of GJB2 mRNA CTD PMID:12629581 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938
JBrowse link
G GJB5 gap junction protein beta 5 decreases expression ISO Cocaine results in decreased expression of GJB5 mRNA CTD PMID:27899881 NCBI chr 1:34,754,777...34,758,513
Ensembl chr 1:34,755,047...34,758,512
JBrowse link
G GJD2 gap junction protein delta 2 affects expression ISO Cocaine affects the expression of GJD2 mRNA; Cocaine affects the expression of GJD2 protein CTD PMID:16138316 NCBI chr15:34,751,032...34,754,998
Ensembl chr15:34,751,032...34,754,998
JBrowse link
G GLI2 GLI family zinc finger 2 decreases expression ISO Cocaine results in decreased expression of GLI2 mRNA CTD PMID:27899881 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653
JBrowse link
G GLP2R glucagon like peptide 2 receptor decreases expression ISO Cocaine results in decreased expression of GLP2R mRNA CTD PMID:17898221 NCBI chr17:9,825,508...9,894,163
Ensembl chr17:9,822,206...9,892,099
JBrowse link
G GLRA1 glycine receptor alpha 1 multiple interactions ISO Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]; Dronabinol inhibits the reaction [Cocaine inhibits the reaction [Glycine results in increased activity of GLRA1 protein]] CTD PMID:32209479 NCBI chr 5:151,822,513...151,924,851
Ensembl chr 5:151,822,513...151,924,842
Ensembl chr 5:151,822,513...151,924,842
JBrowse link
G GLRX3 glutaredoxin 3 affects expression ISO Cocaine affects the expression of GLRX3 mRNA CTD PMID:20187946 NCBI chr10:130,136,391...130,182,877
Ensembl chr10:130,136,391...130,184,521
JBrowse link
G GNAO1 G protein subunit alpha o1 decreases expression
multiple interactions
EXP
ISO
Cocaine results in decreased expression of GNAO1 mRNA
[Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of GNAO1 protein alternative form
CTD PMID:12629581 PMID:19457111 NCBI chr16:56,191,489...56,357,444
Ensembl chr16:56,191,390...56,357,444
Ensembl chr16:56,191,390...56,357,444
JBrowse link
G GNAT1 G protein subunit alpha transducin 1 increases expression ISO Cocaine results in increased expression of GNAT1 mRNA CTD PMID:27899881 NCBI chr 3:50,191,610...50,197,696
Ensembl chr 3:50,191,610...50,197,696
JBrowse link
G GNB1 G protein subunit beta 1 decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of GNB1 mRNA
Cocaine results in increased expression of GNB1 mRNA
CTD PMID:12629581 PMID:16076954 NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,891,117
JBrowse link
G GNB2 G protein subunit beta 2 affects expression ISO Cocaine affects the expression of GNB2 mRNA CTD PMID:20187946 NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174
JBrowse link
G GNB4 G protein subunit beta 4 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA] CTD PMID:17988634 NCBI chr 3:179,396,088...179,451,470
Ensembl chr 3:179,396,088...179,451,476
JBrowse link
G GNG12 G protein subunit gamma 12 affects expression ISO Cocaine affects the expression of GNG12 mRNA CTD PMID:20187946 NCBI chr 1:67,701,475...67,833,467
Ensembl chr 1:67,701,475...67,833,467
JBrowse link
G GNRH1 gonadotropin releasing hormone 1 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of GNRH1 protein
GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]
CTD PMID:31059705 NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654
JBrowse link
G GP2 glycoprotein 2 affects expression ISO Cocaine affects the expression of GP2 mRNA CTD PMID:20187946 NCBI chr16:20,309,574...20,327,513
Ensembl chr16:20,309,572...20,327,808
Ensembl chr16:20,309,572...20,327,808
JBrowse link
G GPC5 glypican 5 increases expression
multiple interactions
ISO Cocaine results in increased expression of GPC5 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]
CTD PMID:18355967 NCBI chr13:91,398,621...92,867,237
Ensembl chr13:91,398,621...92,873,682
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 increases expression ISO Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
JBrowse link
G GPHN gephyrin increases phosphorylation
multiple interactions
ISO Cocaine results in increased phosphorylation of GPHN protein
Win 55212-2 promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein]
CTD PMID:32312805 NCBI chr14:66,507,934...67,181,805
Ensembl chr14:66,507,407...67,181,803
JBrowse link
G GPM6A glycoprotein M6A decreases expression EXP Cocaine results in decreased expression of GPM6A mRNA CTD PMID:12629581 NCBI chr 4:175,632,937...176,002,691
Ensembl chr 4:175,632,934...176,002,664
JBrowse link
G GPM6B glycoprotein M6B decreases expression EXP Cocaine results in decreased expression of GPM6B mRNA CTD PMID:12629581 NCBI chr  X:13,770,922...13,938,713
Ensembl chr  X:13,770,939...13,938,638
JBrowse link
G GPR157 G protein-coupled receptor 157 decreases expression ISO Cocaine results in decreased expression of GPR157 mRNA CTD PMID:27899881 NCBI chr 1:9,100,305...9,129,124
Ensembl chr 1:9,100,305...9,129,102
JBrowse link
G GPR3 G protein-coupled receptor 3 increases expression ISO Cocaine results in increased expression of GPR3 mRNA CTD PMID:27899881 NCBI chr 1:27,392,622...27,395,814
Ensembl chr 1:27,392,622...27,395,814
JBrowse link
G GPR88 G protein-coupled receptor 88 affects expression ISO Cocaine affects the expression of GPR88 mRNA CTD PMID:20187946 NCBI chr 1:100,538,139...100,542,021
Ensembl chr 1:100,538,139...100,542,021
JBrowse link
G GPRASP1 G protein-coupled receptor associated sorting protein 1 affects expression ISO Cocaine affects the expression of GPRASP1 mRNA CTD PMID:20187946 NCBI chr  X:102,651,483...102,659,083
Ensembl chr  X:102,651,092...102,659,083
JBrowse link
G GPSM1 G protein signaling modulator 1 affects expression ISO Cocaine affects the expression of GPSM1 protein CTD PMID:15091342 NCBI chr 9:136,327,539...136,359,605
Ensembl chr 9:136,327,476...136,359,605
JBrowse link
G GPT glutamic--pyruvic transaminase increases activity
multiple interactions
ISO Cocaine results in increased activity of GPT protein
PRKCD protein affects the reaction [Cocaine results in increased activity of GPT protein]; rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein]
CTD PMID:30393195 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX1 glutathione peroxidase 1 increases expression
multiple interactions
affects response to substance
ISO Cocaine results in increased expression of GPX1 protein
GPX1 protein affects the susceptibility to [Cocaine co-treated with prolinedithiocarbamate]; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; prolinedithiocarbamate promotes the reaction [Cocaine results in increased expression of GPX1 protein]
GPX1 protein affects the susceptibility to Cocaine
CTD PMID:31059705 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GRB2 growth factor receptor bound protein 2 increases expression ISO Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
increases response to substance
increases expression
decreases phosphorylation
multiple interactions
affects expression
ISO GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of GRIA1 mRNA; Cocaine results in decreased expression of GRIA1 protein
Cocaine results in increased phosphorylation of GRIA1 protein
GRIA1 protein affects the susceptibility to Cocaine
GRIA1 protein results in increased susceptibility to Cocaine
GRIA1 protein mutant form results in decreased susceptibility to Cocaine; GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of GRIA1 mRNA; Cocaine results in increased expression of GRIA1 protein
Cocaine results in decreased phosphorylation of GRIA1 protein
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIA1 protein; Cocaine results in increased phosphorylation of and results in increased transport of GRIA1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; roscovitine inhibits the reaction [Cocaine results in decreased phosphorylation of GRIA1 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]
Cocaine affects the expression of GRIA1 mRNA; Cocaine affects the expression of GRIA1 protein
Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein]; resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]
CTD PMID:9886066