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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tropane alkaloid
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Accession:CHEBI:37332 term browser browse the term
Synonyms:related_synonym: tropane alkaloids
 alt_id: CHEBI:27154;   CHEBI:27155


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atropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] CTD PMID:16915560 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
G SCT secretin multiple interactions EXP Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] CTD PMID:3562434
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with Atropine] inhibits the reaction [VX results in decreased activity of ACHE protein] CTD PMID:16915560 NCBI chr 6:8,874,747...8,879,926
Ensembl chr 6:8,873,584...8,879,702
JBrowse link
G SCT secretin multiple interactions EXP Atropine inhibits the reaction [SCT protein results in increased abundance of Bicarbonates] CTD PMID:3562434

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 226
    role 226
      biological role 226
        biochemical role 187
          metabolite 180
            alkaloid 14
              tropane alkaloid 2
                (2S)-3-hydroxy-2-phenylpropanoic acid [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                (2S)-3-hydroxy-2-phenylpropanoic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                (2S)-3-hydroxy-2-phenylpropanoic acid [(5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                (6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-one 0
                1-(1-adamantyl)-3-[8-[[1-(2-furanylmethyl)-5-tetrazolyl]methyl]-8-azabicyclo[3.2.1]octan-3-yl]urea 0
                18-demethylgardfloramine 0
                18-demethylgardneramine 0
                19(E)-11-Methoxy-9,18-didemethoxygardneramine 0
                19(E)-18-Demethoxygardfloramine-N(4)-oxide 0
                19(E)-18-demethoxygardfloramine 0
                19(E)-18-demethoxygardneramine 0
                19(E)-9,18-Didemethoxygardneramine 0
                2-(4-bromophenyl)propanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester 0
                2-hydroxy-2-phenylacetic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                2-hydroxy-2-phenylacetic acid [(5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                2-hydroxy-2-phenylacetic acid [(5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                3-hydroxy-2-phenylpropanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester 0
                3-hydroxy-2-phenylpropanoic acid (8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl) ester 0
                3-hydroxy-2-phenylpropanoic acid [(1R,5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                3-hydroxy-2-phenylpropanoic acid [(5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                3-hydroxy-2-phenylpropanoic acid [(5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                3beta,6beta-Dihydroxynortropane 0
                4,4-difluoro-N-[(1S)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]-1-cyclohexanecarboxamide 0
                9-Demethoxy-18-demethylgardneramine 0
                Acetylpseudotropine 0
                Anatoxin a 0
                Brugine 0
                Calystegine C1 0
                Gardfloramine-N(4)-oxide 0
                Knightinol 0
                Littorine 0
                Meteloidine 0
                Nor-psi-tropine 0
                O-hydroxy(phenyl)phosphinoyl ecgonine methyl ester 0
                Physoperuvine 0
                Pseudoecgonine 0
                Schizanthine N 0
                Schizanthine O 0
                Schizanthine P 0
                Scopoline 0
                Tigloidine 0
                Valeroidine 0
                [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate 0
                [(1S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate 0
                atropine oxyde 0
                butylscopolamine + 0
                cocaine 0
                cocaine(1+) + 0
                ecgonine + 0
                ecgonine benzoate 0
                ecgonine methyl ester + 0
                ecgonone methyl ester 0
                gardfloramine 0
                gardneramine 0
                gardneramine-N(4)-oxide 0
                ipratropium + 0
                itasetron 0
                methylatropine 0
                pseudotropine + 0
                scopolamine + 0
                tematropium methylsulfate 0
                tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate + 2
                tropane + 0
                tropanyl 3,5-dimethylbenzoate 0
                tropine + 2
                tropinone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 226
    subatomic particle 226
      composite particle 226
        hadron 226
          baryon 226
            nucleon 226
              atomic nucleus 226
                atom 226
                  main group element atom 219
                    p-block element atom 219
                      carbon group element atom 208
                        carbon atom 207
                          organic molecular entity 207
                            organic molecule 201
                              organic cyclic compound 185
                                organic heterocyclic compound 143
                                  organic heteropolycyclic compound 64
                                    organic heterobicyclic compound 26
                                      azabicycloalkane 2
                                        tropane alkaloid 2
                                          (2S)-3-hydroxy-2-phenylpropanoic acid [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                          (2S)-3-hydroxy-2-phenylpropanoic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                          (2S)-3-hydroxy-2-phenylpropanoic acid [(5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                          (6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-one 0
                                          1-(1-adamantyl)-3-[8-[[1-(2-furanylmethyl)-5-tetrazolyl]methyl]-8-azabicyclo[3.2.1]octan-3-yl]urea 0
                                          18-demethylgardfloramine 0
                                          18-demethylgardneramine 0
                                          19(E)-11-Methoxy-9,18-didemethoxygardneramine 0
                                          19(E)-18-Demethoxygardfloramine-N(4)-oxide 0
                                          19(E)-18-demethoxygardfloramine 0
                                          19(E)-18-demethoxygardneramine 0
                                          19(E)-9,18-Didemethoxygardneramine 0
                                          2-(4-bromophenyl)propanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester 0
                                          2-hydroxy-2-phenylacetic acid [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                          2-hydroxy-2-phenylacetic acid [(5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                                          2-hydroxy-2-phenylacetic acid [(5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester 0
                                          3-hydroxy-2-phenylpropanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester 0
                                          3-hydroxy-2-phenylpropanoic acid (8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl) ester 0
                                          3-hydroxy-2-phenylpropanoic acid [(1R,5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                                          3-hydroxy-2-phenylpropanoic acid [(5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                                          3-hydroxy-2-phenylpropanoic acid [(5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester 0
                                          3beta,6beta-Dihydroxynortropane 0
                                          4,4-difluoro-N-[(1S)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]-1-cyclohexanecarboxamide 0
                                          9-Demethoxy-18-demethylgardneramine 0
                                          Acetylpseudotropine 0
                                          Anatoxin a 0
                                          Brugine 0
                                          Calystegine C1 0
                                          Gardfloramine-N(4)-oxide 0
                                          Knightinol 0
                                          Littorine 0
                                          Meteloidine 0
                                          Nor-psi-tropine 0
                                          O-hydroxy(phenyl)phosphinoyl ecgonine methyl ester 0
                                          Physoperuvine 0
                                          Pseudoecgonine 0
                                          Schizanthine N 0
                                          Schizanthine O 0
                                          Schizanthine P 0
                                          Scopoline 0
                                          Tigloidine 0
                                          Valeroidine 0
                                          [(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate 0
                                          [(1S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate 0
                                          atropine oxyde 0
                                          butylscopolamine + 0
                                          cocaine 0
                                          cocaine(1+) + 0
                                          ecgonine + 0
                                          ecgonine benzoate 0
                                          ecgonine methyl ester + 0
                                          ecgonone methyl ester 0
                                          gardfloramine 0
                                          gardneramine 0
                                          gardneramine-N(4)-oxide 0
                                          ipratropium + 0
                                          itasetron 0
                                          methylatropine 0
                                          pseudotropine + 0
                                          scopolamine + 0
                                          tematropium methylsulfate 0
                                          tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate + 2
                                          tropane + 0
                                          tropanyl 3,5-dimethylbenzoate 0
                                          tropine + 2
                                          tropinone 0
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