The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A monocarboxylic acid that is (E)-penta-2,4-dienoic acid substituted by a 1,3-benzodioxol-5-yl group at position 5. It has been isolated from black pepper (Piper nigrum).
Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]; NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein] piperine results in increased expression of ABCB1 mRNA; piperine results in increased expression of ABCB1 protein piperine analog results in decreased expression of ABCB1 protein
piperine inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [piperine inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]]
piperine results in increased expression of BAX protein [piperine analog co-treated with Paclitaxel] results in increased expression of BAX protein; piperine inhibits the reaction [Curcumin results in decreased expression of BAX protein]
piperine results in decreased expression of BCL2 protein [piperine analog co-treated with Paclitaxel] results in decreased expression of BCL2 protein; [piperine co-treated with Curcumin] results in decreased expression of BCL2 protein
piperine inhibits the reaction [Cadmium results in increased activity of CASP3 protein] piperine results in increased cleavage of CASP3 protein [piperine analog co-treated with Paclitaxel] results in increased cleavage of CASP3 protein; piperine inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]
[piperine co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]]; NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein] piperine results in increased expression of CYP3A4 mRNA; piperine results in increased expression of CYP3A4 protein
piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein] piperine results in decreased localization of FOS protein piperine results in decreased expression of FOS mRNA
piperine inhibits the reaction [beryllium nitrate results in increased activity of GPT protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [piperine inhibits the reaction [beryllium nitrate results in increased activity of GPT protein]]
[Curcumin co-treated with piperine] results in increased expression of HMOX1 mRNA; [Curcumin co-treated with piperine] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [[Curcumin co-treated with piperine] results in increased expression of HMOX1 protein] [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in increased expression of HMOX1 protein]
[Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; tin protoporphyrin IX inhibits the reaction [[Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]
piperine inhibits the reaction [IL2 protein results in increased expression of CCNB1 protein]; piperine inhibits the reaction [IL2 protein results in increased expression of CCND2 protein]; piperine inhibits the reaction [IL2 protein results in increased expression of CDC25C protein]; piperine inhibits the reaction [IL2 protein results in increased expression of CDK1 protein]; piperine inhibits the reaction [IL2 protein results in increased expression of CDK4 protein]; piperine inhibits the reaction [IL2 protein results in increased expression of CDK6 protein]; piperine inhibits the reaction [IL2 protein results in increased phosphorylation of AKT1 protein]; piperine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [IL2 protein results in increased phosphorylation of STAT3 protein]; piperine inhibits the reaction [IL2 protein results in increased phosphorylation of STAT5A protein]; piperine inhibits the reaction [IL2 protein results in increased phosphorylation of STAT5B protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] piperine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] piperine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein] piperine results in decreased expression of MMP9 protein
Ketoconazole inhibits the reaction [piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
[piperine co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]; piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein] piperine binds to NR1I2 protein piperine results in increased activity of NR1I2 protein piperine results in increased expression of NR1I2 protein
piperine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein] piperine results in decreased localization of RELA protein piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]
[piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of SLC9A3 protein]
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