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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:galactan
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Accession:CHEBI:37165 term browser browse the term
Definition:Polysaccharides composed of galactose residues.
Synonyms:related_synonym: Formula=(C12H20O11)n;   galactans
 alt_id: CHEBI:24134;   CHEBI:5249
 xref: KEGG:C05796;   KEGG:G10534;   PMID:8154046



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carrageenan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO Carrageenan results in increased phosphorylation of AKT1 protein
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein]
CTD PMID:26418808 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Anxa1 annexin A1 affects response to substance
multiple interactions
ISO ANXA1 protein affects the susceptibility to Carrageenan
ANXA1 protein affects the susceptibility to [Dexamethasone co-treated with Carrageenan]
CTD PMID:12475898 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Apcs amyloid P component, serum increases expression EXP Carrageenan results in increased expression of APCS protein CTD PMID:22330755 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO
EXP
fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein]
procyanidin B2 inhibits the reaction [Carrageenan results in decreased activity of CAT protein]
CTD PMID:26418808 PMID:28844677 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of CCL2 protein] CTD PMID:12444156 PMID:20383154 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
ISO 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of CCL3 protein] CTD PMID:12444156 PMID:20383154 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions
ISO
EXP
Carrageenan results in increased expression of CCL5 protein
isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]
CTD PMID:12444156 PMID:14654164 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cma1 chymase 1 multiple interactions
increases expression
EXP adelmidrol inhibits the reaction [Carrageenan results in increased expression of CMA1 protein] CTD PMID:18429935 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases secretion
increases expression
EXP
ISO
IMMLG5521 inhibits the reaction [Carrageenan results in increased secretion of CXCL2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:12444156 PMID:14654164 PMID:21549112 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Carrageenan results in increased expression of CXCL1 protein CTD PMID:12444156 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO Carrageenan results in increased expression of EGR1 protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Carrageenan results in increased expression of EGR1 protein]; EGR1 protein inhibits the reaction [Carrageenan results in decreased expression of and affects the localization of TJP1 protein]; NFKBIA protein inhibits the reaction [Carrageenan results in increased expression of EGR1 protein]
CTD PMID:22561171 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one inhibits the reaction [Carrageenan results in increased expression of FOS protein]; Flurbiprofen inhibits the reaction [Carrageenan results in increased expression of FOS protein]; Flurbiprofen promotes the reaction [Urethane inhibits the reaction [Carrageenan results in increased expression of FOS protein]]; Urethane inhibits the reaction [Carrageenan results in increased expression of FOS protein]; Urethane inhibits the reaction [Flurbiprofen inhibits the reaction [Carrageenan results in increased expression of FOS protein]] CTD PMID:1327382 PMID:11164833 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gal galanin and GMAP prepropeptide decreases response to substance ISO GAL protein results in decreased susceptibility to Carrageenan CTD PMID:17999197 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gpr132 G protein-coupled receptor 132 increases expression ISO Carrageenan results in increased expression of GPR132 mRNA CTD PMID:19602228 NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168
JBrowse link
G Gpr4 G protein-coupled receptor 4 increases expression ISO Carrageenan results in increased expression of GPR4 mRNA CTD PMID:19602228 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
JBrowse link
G Gpr65 G-protein coupled receptor 65 increases expression ISO Carrageenan results in increased expression of GPR65 mRNA CTD PMID:19602228 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
EXP procyanidin B2 inhibits the reaction [Carrageenan results in decreased expression of HMOX1 protein] CTD PMID:28844677 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP Carrageenan results in increased expression of HSPA1A protein CTD PMID:15860553
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
EXP
ISO
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of ICAM1 mRNA]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of ICAM1 mRNA]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]; rosiglitazone inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]
IL1R1 protein promotes the reaction [Carrageenan results in increased expression of ICAM1 protein]; PEGylated soluble tumor necrosis factor receptor I inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of ICAM1 protein]
Carrageenan results in increased expression of ICAM1 mRNA; Carrageenan results in increased expression of ICAM1 protein
CTD PMID:11181422 PMID:14709329 PMID:15380531 PMID:22330755 PMID:27803785 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 increases secretion
multiple interactions
increases expression
EXP
ISO
Carrageenan results in increased secretion of IL10 protein
indole-3-guanylhydrazone hydrochloride promotes the reaction [Carrageenan results in increased secretion of IL10 protein]; Indomethacin promotes the reaction [Carrageenan results in increased secretion of IL10 protein]
Indomethacin inhibits the reaction [Carrageenan results in increased expression of IL10 mRNA]; procyanidin B2 inhibits the reaction [Carrageenan results in increased secretion of IL10 protein]; Thioctic Acid promotes the reaction [Carrageenan results in increased expression of IL10 mRNA]
CTD PMID:11181422 PMID:19735303 PMID:28844677 PMID:29499192 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression
ISO Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]; Dexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Dexamethasone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]; Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]; Naloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]] CTD PMID:12182845 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases secretion
increases expression
multiple interactions
ISO
EXP
Carrageenan results in increased secretion of IL1B protein
Carrageenan results in increased expression of IL1B protein
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; indole-3-guanylhydrazone hydrochloride inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]; Indomethacin inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; budlein A inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; IMMLG5521 inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]; N-(2-hydroxybenzoyl)tyramine inhibits the reaction [Carrageenan results in increased expression of IL1B protein]
CTD PMID:11181422 PMID:16368644 PMID:17320857 PMID:20383154 PMID:21549112 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions
increases response to substance
ISO IL1R1 protein promotes the reaction [Carrageenan results in increased expression of ICAM1 protein]; IL1R1 protein promotes the reaction [Carrageenan results in increased expression of SELP protein]; IL1R1 protein promotes the reaction [Carrageenan results in increased expression of TNF protein]; IL1R1 protein promotes the reaction [Carrageenan results in increased expression of TNFRSF8 protein]; IL1R1 protein promotes the reaction [Carrageenan results in increased expression of TNFSF8 protein]
IL1R1 protein results in increased susceptibility to Carrageenan
CTD PMID:15380531 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
ISO
EXP
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of IL6 protein]
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Diclofenac inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; procyanidin B2 inhibits the reaction [Carrageenan results in increased secretion of IL6 protein]; Thiazolidines analog inhibits the reaction [Carrageenan results in increased expression of IL6 protein]
CTD PMID:11181422 PMID:20383154 PMID:22330755 PMID:23774260 PMID:24412305 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Klk7 kallikrein-related peptidase 7 increases expression
multiple interactions
EXP Carrageenan results in increased expression of KLK3 protein
procyanidin B2 inhibits the reaction [Carrageenan results in increased expression of KLK3 protein]
CTD PMID:28844677 NCBI chr 1:94,267,170...94,271,332
Ensembl chr 1:94,266,605...94,271,332
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Carrageenan results in increased phosphorylation of MAPK1 protein
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein]
CTD PMID:26418808 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein] CTD PMID:26418808 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
EXP Carrageenan results in increased expression of MMP9 protein
adelmidrol inhibits the reaction [Carrageenan results in increased expression of MMP9 protein]
CTD PMID:18429935 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression
EXP adelmidrol inhibits the reaction [Carrageenan results in increased activity of MPO protein]; arvelexin analog inhibits the reaction [Carrageenan results in increased expression of MPO protein]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased activity of MPO protein]; Diclofenac inhibits the reaction [Carrageenan results in increased activity of MPO protein]; Ibuprofen inhibits the reaction [Carrageenan results in increased expression of MPO protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Carrageenan results in increased activity of MPO protein]; N-(2-hydroxybenzoyl)tyramine inhibits the reaction [Carrageenan results in increased activity of MPO protein]; Thiazolidines analog inhibits the reaction [Carrageenan results in increased activity of MPO protein] CTD PMID:9890637 PMID:15860553 PMID:18429935 PMID:23872256 PMID:24412305 More... NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [Methylnitrosourea co-treated with Carrageenan] results in increased expression of MT1 protein CTD PMID:15928667 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
EXP Carrageenan affects the localization of NFE2L2 protein
procyanidin B2 inhibits the reaction [Carrageenan affects the localization of NFE2L2 protein]
CTD PMID:28844677 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO NFKBIA protein inhibits the reaction [Carrageenan results in increased expression of EGR1 protein] CTD PMID:22561171 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor increases expression
multiple interactions
EXP Carrageenan results in increased expression of NGF protein
Dexamethasone inhibits the reaction [Carrageenan results in increased expression of NGF protein]
CTD PMID:10653021 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
increases activity
EXP
ISO
adelmidrol inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NOS2 protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]
fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]
Carrageenan results in increased activity of NOS2 protein
Carrageenan results in increased expression of NOS2 mRNA; Carrageenan results in increased expression of NOS2 protein
CTD PMID:7542281 PMID:9890637 PMID:15860553 PMID:18429935 PMID:22330755 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
EXP Carrageenan results in decreased expression of NQO1 protein
procyanidin B2 inhibits the reaction [Carrageenan results in decreased expression of NQO1 protein]
CTD PMID:28844677 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Oprm1 opioid receptor, mu 1 decreases expression ISO Carrageenan results in decreased expression of OPRM1 protein CTD PMID:30763598 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions EXP [(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Carrageenan CTD PMID:16982702 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression
multiple interactions
EXP Carrageenan results in increased expression of PECAM1 protein
adelmidrol inhibits the reaction [Carrageenan results in increased expression of PECAM1 protein]
CTD PMID:18429935 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Ptges prostaglandin E synthase multiple interactions
increases expression
EXP arvelexin analog inhibits the reaction [Carrageenan results in increased expression of PTGES protein] CTD PMID:17258197 PMID:25451575 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions
increases activity
EXP 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid inhibits the reaction [[Carrageenan results in increased activity of PTGES2 protein] which results in increased chemical synthesis of Dinoprostone]; [Carrageenan results in increased activity of PTGES2 protein] which results in increased chemical synthesis of Dinoprostone CTD PMID:19934399 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP
ISO
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; dragon's blood inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Ketorolac inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]; nimesulide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; resveratrol inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Thioctic Acid inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; triflusal inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
Carrageenan results in increased expression of PTGS2 mRNA; Carrageenan results in increased expression of PTGS2 protein
CTD PMID:10101034 PMID:14654164 PMID:15860553 PMID:17258197 PMID:18814970 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
increases localization
multiple interactions
ISO
EXP
Carrageenan results in increased phosphorylation of RELA protein
Carrageenan results in increased localization of RELA protein
IMMLG5521 inhibits the reaction [Carrageenan results in increased localization of RELA protein]
CTD PMID:21549112 PMID:22561171 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Selp selectin P increases expression
multiple interactions
EXP
ISO
Carrageenan results in increased expression of SELP protein
IL1R1 protein promotes the reaction [Carrageenan results in increased expression of SELP protein]; PEGylated soluble tumor necrosis factor receptor I inhibits the reaction [Carrageenan results in increased expression of SELP protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of SELP protein]
imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of SELP protein]
CTD PMID:11181422 PMID:15380531 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Sstr4 somatostatin receptor 4 decreases response to substance ISO SSTR4 results in decreased susceptibility to Carrageenan CTD PMID:19622729 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases secretion ISO Carrageenan results in increased secretion of TGFB1 protein CTD PMID:16368644 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [Carrageenan results in decreased expression of and affects the localization of TJP1 protein]; Carrageenan results in decreased expression of and affects the localization of TJP1 protein; EGR1 protein inhibits the reaction [Carrageenan results in decreased expression of and affects the localization of TJP1 protein] CTD PMID:22561171 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression
ISO
EXP
Carrageenan results in increased secretion of TNF protein
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; adelmidrol inhibits the reaction [Carrageenan results in increased expression of TNF protein]; budlein A inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of TNF protein]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of TNF protein]; IMMLG5521 inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; N-(2-hydroxybenzoyl)tyramine inhibits the reaction [Carrageenan results in increased expression of TNF protein]; procyanidin B2 inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Rutin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Thiazolidines analog inhibits the reaction [Carrageenan results in increased expression of TNF protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of TNF protein]; IL1R1 protein promotes the reaction [Carrageenan results in increased expression of TNF protein]; indole-3-guanylhydrazone hydrochloride inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; Indomethacin inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; PEGylated soluble tumor necrosis factor receptor I inhibits the reaction [Carrageenan results in increased expression of TNF protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of TNF protein]
CTD PMID:11181422 PMID:12444156 PMID:14654164 PMID:15380531 PMID:16368644 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions
increases expression
ISO IL1R1 protein promotes the reaction [Carrageenan results in increased expression of TNFRSF8 protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of TNFRSF8 protein] CTD PMID:15380531 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Tnfsf8 TNF superfamily member 8 increases expression
multiple interactions
increases response to substance
ISO Carrageenan results in increased expression of TNFSF8 protein
IL1R1 protein promotes the reaction [Carrageenan results in increased expression of TNFSF8 protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of ICAM1 protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of SELP protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of TNF protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of TNFRSF8 protein]; TNFSF8 protein promotes the reaction [Carrageenan results in increased expression of TNFSF8 protein]
TNFSF8 protein results in increased susceptibility to Carrageenan
CTD PMID:15380531 NCBI chr 5:77,253,881...77,277,078
Ensembl chr 5:77,251,373...77,277,421
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions
EXP Carrageenan results in increased expression of VCAM1 mRNA
Dexamethasone inhibits the reaction [Carrageenan results in increased expression of VCAM1 mRNA]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of VCAM1 mRNA]
CTD PMID:27803785 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      molecular entity 19799
        polyatomic entity 19721
          macromolecule 3518
            biomacromolecule 3243
              polysaccharide 3077
                homopolysaccharide 1376
                  galactan 50
                    (1->3)-beta-D-galactopyranan 0
                    (1->4)-beta-D-galactan 0
                    [(1->4)-alpha-D-galacturonosyl]n 0
                    [arabino-(1->6)-galacto]-(1->3)-beta-D-galactan 0
                    agarose + 0
                    arabinogalactan 0
                    carrageenan + 50
                    galactan derivative 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  carbohydrates and carbohydrate derivatives 12342
                                    carbohydrate 12342
                                      polysaccharide 3077
                                        homopolysaccharide 1376
                                          galactan 50
                                            (1->3)-beta-D-galactopyranan 0
                                            (1->4)-beta-D-galactan 0
                                            [(1->4)-alpha-D-galacturonosyl]n 0
                                            [arabino-(1->6)-galacto]-(1->3)-beta-D-galactan 0
                                            agarose + 0
                                            arabinogalactan 0
                                            carrageenan + 50
                                            galactan derivative 0
paths to the root