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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cinoxacin
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Accession:CHEBI:3716 term browser browse the term
Definition:A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.
Synonyms:exact_synonym: 1-ethyl-4-oxo-1,4-dihydro[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
 related_synonym: 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid;   5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid;   Formula=C12H10N2O5;   InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17);   InChIKey=VDUWPHTZYNWKRN-UHFFFAOYSA-N;   SMILES=CCn1nc(C(O)=O)c(=O)c2cc3OCOc3cc12;   cinoxacine;   cinoxacino;   cinoxacinum
 alt_id: CHEBI:314701
 xref: Beilstein:1084304;   CAS:28657-80-9;   DrugBank:DB00827;   Drug_Central:657;   HMDB:HMDB0014965;   KEGG:D00872;   LINCS:LSM-6552
 xref_mesh: MESH:D002937
 xref: PMID:12204384;   PMID:16295658;   PMID:29438107;   PMID:3005575;   PMID:3147004;   PMID:6226270;   Patent:DE2005104;   Patent:US3669965;   Patent:US6441167;   VSDB:1881;   Wikipedia:Cinoxacin


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cinoxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-Ha RT1 class II, locus Ha affects expression ISO Cinoxacin affects the expression of HLA-DPA1 mRNA CTD PMID:25811541 NCBI chr20:4,760,631...4,770,662 JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        pharmaceutical 19319
          drug 19319
            antiinfective agent 14114
              cinoxacin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        oxo carboxylic acid 6291
                                          cinoxacin 1
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