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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:epichlorohydrin
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Accession:CHEBI:37144 term browser browse the term
Definition:An epoxide that is 1,2-epoxypropene in which one of the methyl hydrogens is substituted by chlorine.
Synonyms:related_synonym: (RS)-3-chloro-1,2-epoxypropane;   (chloromethyl)ethylene oxide;   1-Chloro-2,3-epoxypropane;   2,3-epoxypropyl chloride;   2-(chloromethyl)oxirane;   Formula=C3H5ClO;   InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2;   InChIKey=BRLQWZUYTZBJKN-UHFFFAOYSA-N;   SMILES=ClCC1CO1;   alpha-epichlorohydrin;   chloromethyloxirane;   gamma-chloropropylene oxide
 alt_id: CHEBI:18720;   CHEBI:34737
 xref: Beilstein:79785;   CAS:106-89-8;   CAS:13403-37-7;   Gmelin:164180;   HMDB:HMDB0034232;   KEGG:C14449
 xref_mesh: MESH:D004811
 xref: PMID:17441735;   PMID:20547378;   PMID:8586023;   PPDB:1733;   Patent:US2011054197;   Reaxys:79785;   UM-BBD_compID:c0077;   Wikipedia:Epichlorohydrin



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epichlorohydrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMPD3 adenosine monophosphate deaminase 3 increases expression EXP Epichlorohydrin results in increased expression of AMPD3 mRNA CTD PMID:24211530 NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression EXP Epichlorohydrin results in increased expression of APAF1 mRNA CTD PMID:29792945 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases expression EXP Epichlorohydrin results in increased expression of BAK1 mRNA CTD PMID:29792945 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP Epichlorohydrin results in increased expression of BAX mRNA CTD PMID:29792945 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 increases expression EXP Epichlorohydrin results in increased expression of BBC3 mRNA CTD PMID:29792945 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression EXP Epichlorohydrin results in increased expression of BCL2 mRNA CTD PMID:29792945 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L11 BCL2 like 11 decreases expression EXP Epichlorohydrin results in decreased expression of BCL2L11 mRNA CTD PMID:29792945 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
JBrowse link
G BOK BCL2 family apoptosis regulator BOK increases expression EXP Epichlorohydrin results in increased expression of BOK mRNA CTD PMID:29792945 NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,424...241,574,131
JBrowse link
G CASP2 caspase 2 decreases expression EXP Epichlorohydrin results in decreased expression of CASP2 mRNA CTD PMID:29792945 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
JBrowse link
G CASP8 caspase 8 increases expression EXP Epichlorohydrin results in increased expression of CASP8 mRNA CTD PMID:29792945 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 increases expression EXP Epichlorohydrin results in increased expression of CASP9 mRNA CTD PMID:29792945 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CHST11 carbohydrate sulfotransferase 11 affects response to substance EXP CHST11 gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr12:104,456,948...104,762,014
Ensembl chr12:104,455,295...104,762,014
JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein decreases expression EXP Epichlorohydrin results in decreased expression of DIABLO mRNA CTD PMID:29792945 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
JBrowse link
G DNER delta/notch like EGF repeat containing affects response to substance EXP DNER gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 2:229,357,629...229,714,555
Ensembl chr 2:229,357,629...229,714,555
JBrowse link
G FTH1 ferritin heavy chain 1 increases expression EXP Epichlorohydrin results in increased expression of FTH1 mRNA CTD PMID:24211530 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
JBrowse link
G FTL ferritin light chain increases expression EXP Epichlorohydrin results in increased expression of FTL mRNA CTD PMID:24211530 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Epichlorohydrin results in increased expression of GCLM mRNA CTD PMID:24211530 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GSTM1 glutathione S-transferase mu 1 affects response to substance EXP GSTM1 gene polymorphism affects the susceptibility to Epichlorohydrin CTD PMID:15091291 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Epichlorohydrin results in increased expression of HMOX1 mRNA CTD PMID:24211530 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G KCP kielin cysteine rich BMP regulator affects response to substance EXP KCP gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 7:128,876,865...128,910,709
Ensembl chr 7:128,862,042...128,910,719
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Epichlorohydrin results in increased expression of MYC mRNA CTD PMID:24211530 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Epichlorohydrin results in increased expression of NQO1 mRNA CTD PMID:24211530 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G SEL1L3 SEL1L family member 3 increases expression EXP Epichlorohydrin results in increased expression of SEL1L3 mRNA CTD PMID:24211530 NCBI chr 4:25,713,964...25,863,566
Ensembl chr 4:25,747,433...25,863,760
JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP Epichlorohydrin results in increased expression of SLC7A11 mRNA CTD PMID:24211530 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SQSTM1 sequestosome 1 increases expression EXP Epichlorohydrin results in increased expression of SQSTM1 mRNA CTD PMID:24211530 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SYNE2 spectrin repeat containing nuclear envelope protein 2 decreases expression EXP Epichlorohydrin results in decreased expression of SYNE2 mRNA CTD PMID:24211530 NCBI chr14:63,761,596...64,226,449
Ensembl chr14:63,761,899...64,226,433
JBrowse link
G TANK TRAF family member associated NFKB activator increases expression EXP Epichlorohydrin results in increased expression of TANK mRNA CTD PMID:29792945 NCBI chr 2:161,136,963...161,236,230
Ensembl chr 2:161,136,908...161,236,230
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a decreases expression EXP Epichlorohydrin results in decreased expression of TNFRSF10A mRNA CTD PMID:22723965 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b increases expression EXP Epichlorohydrin results in increased expression of TNFRSF10B mRNA CTD PMID:22723965 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 increases expression EXP Epichlorohydrin results in increased expression of TNFRSF9 mRNA CTD PMID:22723965 NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
JBrowse link
G TNNT2 troponin T2, cardiac type decreases expression EXP Epichlorohydrin results in decreased expression of TNNT2 mRNA CTD PMID:24211530 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TRIM16L tripartite motif containing 16 like (pseudogene) increases expression EXP Epichlorohydrin results in increased expression of TRIM16L mRNA CTD PMID:24211530 NCBI chr17:18,697,998...18,736,112
Ensembl chr17:18,722,237...18,735,460
Ensembl chr17:18,722,237...18,735,460
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP Epichlorohydrin results in increased expression of TXNRD1 mRNA CTD PMID:24211530 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    chemical entity 26019
      molecular entity 25997
        main group molecular entity 25840
          gas molecular entity 20747
            oxirane 11476
              epoxide 11475
                epichlorohydrin 33
                  (R)-epichlorohydrin 0
                  (S)-epichlorohydrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            organic molecule 25228
                              organic cyclic compound 24279
                                organic heterocyclic compound 22322
                                  organic heteromonocyclic compound 19239
                                    saturated organic heteromonocyclic parent 11497
                                      oxirane 11476
                                        epoxide 11475
                                          1,2-epoxypropane 1157
                                            epichlorohydrin 33
                                              (R)-epichlorohydrin 0
                                              (S)-epichlorohydrin 0
paths to the root