CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: epichlorohydrin
Accession: CHEBI:37144
browse the term
Definition: An epoxide that is 1,2-epoxypropene in which one of the methyl hydrogens is substituted by chlorine.
Synonyms: related_synonym: (RS)-3-chloro-1,2-epoxypropane; (chloromethyl)ethylene oxide; 1-Chloro-2,3-epoxypropane; 2,3-epoxypropyl chloride; 2-(chloromethyl)oxirane; Formula=C3H5ClO; InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2; InChIKey=BRLQWZUYTZBJKN-UHFFFAOYSA-N; SMILES=ClCC1CO1; alpha-epichlorohydrin; chloromethyloxirane; gamma-chloropropylene oxide
alt_id: CHEBI:18720; CHEBI:34737
xref: Beilstein:79785; CAS:106-89-8; CAS:13403-37-7; Gmelin:164180; HMDB:HMDB0034232; KEGG:C14449
xref_mesh: MESH:D004811
xref: PMID:17441735; PMID:20547378; PMID:8586023; PPDB:1733; Patent:US2011054197; Reaxys:79785; UM-BBD_compID:c0077; Wikipedia:Epichlorohydrin
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AMPD3
adenosine monophosphate deaminase 3
increases expression
EXP
Epichlorohydrin results in increased expression of AMPD3 mRNA
CTD
PMID:24211530
NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579
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APAF1
apoptotic peptidase activating factor 1
increases expression
EXP
Epichlorohydrin results in increased expression of APAF1 mRNA
CTD
PMID:29792945
NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
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BAK1
BCL2 antagonist/killer 1
increases expression
EXP
Epichlorohydrin results in increased expression of BAK1 mRNA
CTD
PMID:29792945
NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
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BAX
BCL2 associated X, apoptosis regulator
increases expression
EXP
Epichlorohydrin results in increased expression of BAX mRNA
CTD
PMID:29792945
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BBC3
BCL2 binding component 3
increases expression
EXP
Epichlorohydrin results in increased expression of BBC3 mRNA
CTD
PMID:29792945
NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
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BCL2
BCL2 apoptosis regulator
increases expression
EXP
Epichlorohydrin results in increased expression of BCL2 mRNA
CTD
PMID:29792945
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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BCL2L11
BCL2 like 11
decreases expression
EXP
Epichlorohydrin results in decreased expression of BCL2L11 mRNA
CTD
PMID:29792945
NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
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BOK
BCL2 family apoptosis regulator BOK
increases expression
EXP
Epichlorohydrin results in increased expression of BOK mRNA
CTD
PMID:29792945
NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,424...241,574,131
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CASP2
caspase 2
decreases expression
EXP
Epichlorohydrin results in decreased expression of CASP2 mRNA
CTD
PMID:29792945
NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
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CASP8
caspase 8
increases expression
EXP
Epichlorohydrin results in increased expression of CASP8 mRNA
CTD
PMID:29792945
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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CASP9
caspase 9
increases expression
EXP
Epichlorohydrin results in increased expression of CASP9 mRNA
CTD
PMID:29792945
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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CHST11
carbohydrate sulfotransferase 11
affects response to substance
EXP
CHST11 gene SNP affects the susceptibility to Epichlorohydrin
CTD
PMID:25622337
NCBI chr12:104,456,948...104,762,014
Ensembl chr12:104,455,295...104,762,014
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DIABLO
diablo IAP-binding mitochondrial protein
decreases expression
EXP
Epichlorohydrin results in decreased expression of DIABLO mRNA
CTD
PMID:29792945
NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
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DNER
delta/notch like EGF repeat containing
affects response to substance
EXP
DNER gene SNP affects the susceptibility to Epichlorohydrin
CTD
PMID:25622337
NCBI chr 2:229,357,629...229,714,555
Ensembl chr 2:229,357,629...229,714,555
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FTH1
ferritin heavy chain 1
increases expression
EXP
Epichlorohydrin results in increased expression of FTH1 mRNA
CTD
PMID:24211530
NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
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FTL
ferritin light chain
increases expression
EXP
Epichlorohydrin results in increased expression of FTL mRNA
CTD
PMID:24211530
NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
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GCLM
glutamate-cysteine ligase modifier subunit
increases expression
EXP
Epichlorohydrin results in increased expression of GCLM mRNA
CTD
PMID:24211530
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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GSTM1
glutathione S-transferase mu 1
affects response to substance
EXP
GSTM1 gene polymorphism affects the susceptibility to Epichlorohydrin
CTD
PMID:15091291
NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
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HMOX1
heme oxygenase 1
increases expression
EXP
Epichlorohydrin results in increased expression of HMOX1 mRNA
CTD
PMID:24211530
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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KCP
kielin cysteine rich BMP regulator
affects response to substance
EXP
KCP gene SNP affects the susceptibility to Epichlorohydrin
CTD
PMID:25622337
NCBI chr 7:128,876,865...128,910,709
Ensembl chr 7:128,862,042...128,910,719
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MYC
MYC proto-oncogene, bHLH transcription factor
increases expression
EXP
Epichlorohydrin results in increased expression of MYC mRNA
CTD
PMID:24211530
NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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NQO1
NAD(P)H quinone dehydrogenase 1
increases expression
EXP
Epichlorohydrin results in increased expression of NQO1 mRNA
CTD
PMID:24211530
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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SEL1L3
SEL1L family member 3
increases expression
EXP
Epichlorohydrin results in increased expression of SEL1L3 mRNA
CTD
PMID:24211530
NCBI chr 4:25,713,964...25,863,566
Ensembl chr 4:25,747,433...25,863,760
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SLC7A11
solute carrier family 7 member 11
increases expression
EXP
Epichlorohydrin results in increased expression of SLC7A11 mRNA
CTD
PMID:24211530
NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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SQSTM1
sequestosome 1
increases expression
EXP
Epichlorohydrin results in increased expression of SQSTM1 mRNA
CTD
PMID:24211530
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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SYNE2
spectrin repeat containing nuclear envelope protein 2
decreases expression
EXP
Epichlorohydrin results in decreased expression of SYNE2 mRNA
CTD
PMID:24211530
NCBI chr14:63,761,596...64,226,449
Ensembl chr14:63,761,899...64,226,433
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TANK
TRAF family member associated NFKB activator
increases expression
EXP
Epichlorohydrin results in increased expression of TANK mRNA
CTD
PMID:29792945
NCBI chr 2:161,136,963...161,236,230
Ensembl chr 2:161,136,908...161,236,230
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TNFRSF10A
TNF receptor superfamily member 10a
decreases expression
EXP
Epichlorohydrin results in decreased expression of TNFRSF10A mRNA
CTD
PMID:22723965
NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
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TNFRSF10B
TNF receptor superfamily member 10b
increases expression
EXP
Epichlorohydrin results in increased expression of TNFRSF10B mRNA
CTD
PMID:22723965
NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
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TNFRSF9
TNF receptor superfamily member 9
increases expression
EXP
Epichlorohydrin results in increased expression of TNFRSF9 mRNA
CTD
PMID:22723965
NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
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TNNT2
troponin T2, cardiac type
decreases expression
EXP
Epichlorohydrin results in decreased expression of TNNT2 mRNA
CTD
PMID:24211530
NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
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TRIM16L
tripartite motif containing 16 like (pseudogene)
increases expression
EXP
Epichlorohydrin results in increased expression of TRIM16L mRNA
CTD
PMID:24211530
NCBI chr17:18,697,998...18,736,112
Ensembl chr17:18,722,237...18,735,460 Ensembl chr17:18,722,237...18,735,460
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TXNRD1
thioredoxin reductase 1
increases expression
EXP
Epichlorohydrin results in increased expression of TXNRD1 mRNA
CTD
PMID:24211530
NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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