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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:epichlorohydrin
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Accession:CHEBI:37144 term browser browse the term
Definition:An epoxide that is 1,2-epoxypropene in which one of the methyl hydrogens is substituted by chlorine.
Synonyms:related_synonym: (RS)-3-chloro-1,2-epoxypropane;   (chloromethyl)ethylene oxide;   1-Chloro-2,3-epoxypropane;   2,3-epoxypropyl chloride;   2-(chloromethyl)oxirane;   Formula=C3H5ClO;   InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2;   InChIKey=BRLQWZUYTZBJKN-UHFFFAOYSA-N;   SMILES=ClCC1CO1;   alpha-epichlorohydrin;   chloromethyloxirane;   gamma-chloropropylene oxide
 alt_id: CHEBI:18720;   CHEBI:34737
 xref: Beilstein:79785;   CAS:106-89-8;   CAS:13403-37-7;   Gmelin:164180;   HMDB:HMDB0034232;   KEGG:C14449
 xref_mesh: MESH:D004811
 xref: PMID:17441735;   PMID:20547378;   PMID:8586023;   PPDB:1733;   Patent:US2011054197;   Reaxys:79785;   UM-BBD_compID:c0077;   Wikipedia:Epichlorohydrin


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epichlorohydrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO Epichlorohydrin results in increased expression of AMPD3 mRNA CTD PMID:24211530 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Epichlorohydrin results in increased expression of APAF1 mRNA CTD PMID:29792945 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Epichlorohydrin results in increased expression of BAK1 mRNA CTD PMID:29792945 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Epichlorohydrin results in increased expression of BAX mRNA CTD PMID:29792945 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Epichlorohydrin results in increased expression of BBC3 mRNA CTD PMID:29792945 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Epichlorohydrin results in increased expression of BCL2 mRNA CTD PMID:29792945 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l11 BCL2 like 11 decreases expression ISO Epichlorohydrin results in decreased expression of BCL2L11 mRNA CTD PMID:29792945 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression ISO Epichlorohydrin results in increased expression of BOK mRNA CTD PMID:29792945 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Casp2 caspase 2 decreases expression ISO Epichlorohydrin results in decreased expression of CASP2 mRNA CTD PMID:29792945 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp8 caspase 8 increases expression ISO Epichlorohydrin results in increased expression of CASP8 mRNA CTD PMID:29792945 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression ISO Epichlorohydrin results in increased expression of CASP9 mRNA CTD PMID:29792945 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 affects response to substance ISO CHST11 gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases expression ISO Epichlorohydrin results in decreased expression of DIABLO mRNA CTD PMID:29792945 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dner delta/notch-like EGF repeat containing affects response to substance ISO DNER gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 9:91,965,866...92,291,172
Ensembl chr 9:91,965,866...92,291,220
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Epichlorohydrin results in increased expression of FTH1 mRNA CTD PMID:24211530 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Epichlorohydrin results in increased expression of FTL mRNA CTD PMID:24211530 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Epichlorohydrin results in increased expression of GCLM mRNA CTD PMID:24211530 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Epichlorohydrin CTD PMID:15091291 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Epichlorohydrin results in increased expression of HMOX1 mRNA CTD PMID:24211530 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Kcp kielin cysteine rich BMP regulator affects response to substance ISO KCP gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 4:56,750,782...56,796,878
Ensembl chr 4:56,760,220...56,786,754
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Epichlorohydrin results in increased expression of MYC mRNA CTD PMID:24211530 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Epichlorohydrin results in increased expression of NQO1 mRNA CTD PMID:24211530 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Sel1l3 SEL1L family member 3 increases expression ISO Epichlorohydrin results in increased expression of SEL1L3 mRNA CTD PMID:24211530 NCBI chr14:60,122,968...60,229,565
Ensembl chr14:60,123,169...60,229,734
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Epichlorohydrin results in increased expression of SLC7A11 mRNA CTD PMID:24211530 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Epichlorohydrin results in increased expression of SQSTM1 mRNA CTD PMID:24211530 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression ISO Epichlorohydrin results in decreased expression of SYNE2 mRNA CTD PMID:24211530 NCBI chr 6:98,884,269...99,153,551 JBrowse link
G Tank TRAF family member-associated NFKB activator increases expression ISO Epichlorohydrin results in increased expression of TANK mRNA CTD PMID:29792945 NCBI chr 3:47,439,007...47,515,706
Ensembl chr 3:47,439,076...47,515,700
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO Epichlorohydrin results in decreased expression of TNFRSF10A mRNA CTD PMID:22723965 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Epichlorohydrin results in increased expression of TNFRSF9 mRNA CTD PMID:22723965 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO Epichlorohydrin results in decreased expression of TNNT2 mRNA CTD PMID:24211530 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Epichlorohydrin results in increased expression of TXNRD1 mRNA CTD PMID:24211530 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19771
        main group molecular entity 19665
          gas molecular entity 17756
            oxirane 9523
              epoxide 9522
                epichlorohydrin 31
                  (R)-epichlorohydrin 0
                  (S)-epichlorohydrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic molecule 19505
                              organic cyclic compound 19332
                                organic heterocyclic compound 18519
                                  organic heteromonocyclic compound 16987
                                    saturated organic heteromonocyclic parent 9543
                                      oxirane 9523
                                        epoxide 9522
                                          1,2-epoxypropane 826
                                            epichlorohydrin 31
                                              (R)-epichlorohydrin 0
                                              (S)-epichlorohydrin 0
paths to the root