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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:epichlorohydrin
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Accession:CHEBI:37144 term browser browse the term
Definition:An epoxide that is 1,2-epoxypropene in which one of the methyl hydrogens is substituted by chlorine.
Synonyms:related_synonym: (RS)-3-chloro-1,2-epoxypropane;   (chloromethyl)ethylene oxide;   1-Chloro-2,3-epoxypropane;   2,3-epoxypropyl chloride;   2-(chloromethyl)oxirane;   Formula=C3H5ClO;   InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2;   InChIKey=BRLQWZUYTZBJKN-UHFFFAOYSA-N;   SMILES=ClCC1CO1;   alpha-epichlorohydrin;   chloromethyloxirane;   gamma-chloropropylene oxide
 alt_id: CHEBI:18720;   CHEBI:34737
 xref: Beilstein:79785;   CAS:106-89-8;   CAS:13403-37-7;   Gmelin:164180;   HMDB:HMDB0034232;   KEGG:C14449
 xref_mesh: MESH:D004811
 xref: PMID:17441735;   PMID:20547378;   PMID:8586023;   PPDB:1733;   Patent:US2011054197;   Reaxys:79785;   UM-BBD_compID:c0077;   Wikipedia:Epichlorohydrin



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epichlorohydrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO Epichlorohydrin results in increased expression of AMPD3 mRNA CTD PMID:24211530 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Epichlorohydrin results in increased expression of APAF1 mRNA CTD PMID:29792945 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Epichlorohydrin results in increased expression of BAK1 mRNA CTD PMID:29792945 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Epichlorohydrin results in increased expression of BAX mRNA CTD PMID:29792945 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Epichlorohydrin results in increased expression of BBC3 mRNA CTD PMID:29792945 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Epichlorohydrin results in increased expression of BCL2 mRNA CTD PMID:29792945 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l11 BCL2 like 11 decreases expression ISO Epichlorohydrin results in decreased expression of BCL2L11 mRNA CTD PMID:29792945 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression ISO Epichlorohydrin results in increased expression of BOK mRNA CTD PMID:29792945 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Casp2 caspase 2 decreases expression ISO Epichlorohydrin results in decreased expression of CASP2 mRNA CTD PMID:29792945 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp8 caspase 8 increases expression ISO Epichlorohydrin results in increased expression of CASP8 mRNA CTD PMID:29792945 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression ISO Epichlorohydrin results in increased expression of CASP9 mRNA CTD PMID:29792945 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 affects response to substance ISO CHST11 gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases expression ISO Epichlorohydrin results in decreased expression of DIABLO mRNA CTD PMID:29792945 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dner delta/notch-like EGF repeat containing affects response to substance ISO DNER gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 9:85,586,985...85,902,820
Ensembl chr 9:85,586,987...85,902,637
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Epichlorohydrin results in increased expression of FTH1 mRNA CTD PMID:24211530 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Epichlorohydrin results in increased expression of FTL mRNA CTD PMID:24211530 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Epichlorohydrin results in increased expression of GCLM mRNA CTD PMID:24211530 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Epichlorohydrin CTD PMID:15091291 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Epichlorohydrin results in increased expression of HMOX1 mRNA CTD PMID:24211530 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Kcp kielin cysteine rich BMP regulator affects response to substance ISO KCP gene SNP affects the susceptibility to Epichlorohydrin CTD PMID:25622337 NCBI chr 4:58,082,856...58,118,170
Ensembl chr 4:58,082,857...58,109,768
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Epichlorohydrin results in increased expression of MYC mRNA CTD PMID:24211530 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Epichlorohydrin results in increased expression of NQO1 mRNA CTD PMID:24211530 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Sel1l3 SEL1L family member 3 increases expression ISO Epichlorohydrin results in increased expression of SEL1L3 mRNA CTD PMID:24211530 NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Epichlorohydrin results in increased expression of SLC7A11 mRNA CTD PMID:24211530 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Epichlorohydrin results in increased expression of SQSTM1 mRNA CTD PMID:24211530 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression ISO Epichlorohydrin results in decreased expression of SYNE2 mRNA CTD PMID:24211530 NCBI chr 6:94,537,088...94,848,085 JBrowse link
G Tank TRAF family member-associated NFKB activator increases expression ISO Epichlorohydrin results in increased expression of TANK mRNA CTD PMID:29792945 NCBI chr 3:46,114,253...46,190,270
Ensembl chr 3:46,114,274...46,190,264
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO Epichlorohydrin results in decreased expression of TNFRSF10A mRNA CTD PMID:22723965 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Epichlorohydrin results in increased expression of TNFRSF9 mRNA CTD PMID:22723965 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO Epichlorohydrin results in decreased expression of TNNT2 mRNA CTD PMID:24211530 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Epichlorohydrin results in increased expression of TXNRD1 mRNA CTD PMID:24211530 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      molecular entity 19799
        main group molecular entity 19698
          gas molecular entity 17919
            oxirane 9768
              epoxide 9767
                epichlorohydrin 31
                  (R)-epichlorohydrin 0
                  (S)-epichlorohydrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteromonocyclic compound 17120
                                    saturated organic heteromonocyclic parent 9797
                                      oxirane 9768
                                        epoxide 9767
                                          1,2-epoxypropane 860
                                            epichlorohydrin 31
                                              (R)-epichlorohydrin 0
                                              (S)-epichlorohydrin 0
paths to the root