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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ortho-fused tricyclic hydrocarbon
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Accession:CHEBI:37089 term browser browse the term
Synonyms:related_synonym: ortho-fused tricyclic hydrocarbons


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2-acetamidofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin increases expression ISO 2-Acetylaminofluorene results in increased expression of AAAS mRNA CTD PMID:21607683 NCBI chr 7:143,937,198...143,956,668
Ensembl chr 7:143,937,199...143,956,668
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases expression
multiple interactions
increases activity
ISO
EXP
2-Acetylaminofluorene results in decreased expression of ABCB1 mRNA
2-Acetylaminofluorene results in increased expression of ABCB1 mRNA; 2-Acetylaminofluorene results in increased expression of ABCB1A mRNA
lipopolysaccharide, E coli O55-B5 inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1A mRNA]
2-Acetylaminofluorene results in increased expression of ABCB1 mRNA; 2-Acetylaminofluorene results in increased expression of ABCB1 protein
Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]; Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 protein]
2-Acetylaminofluorene results in increased activity of ABCB1 protein
[2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA; [2-Acetylaminofluorene results in increased activity of RAC1 protein] which results in increased expression of ABCB1 mRNA; [RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]
CTD PMID:11170838, PMID:11960367, PMID:12387747, PMID:17303067, PMID:17669244, PMID:21784091, PMID:22213190 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of ABCB1B mRNA; 2-Acetylaminofluorene results in increased expression of ABCB1B protein
[2-Acetylaminofluorene results in increased abundance of Reactive Oxygen Species] which results in increased expression of ABCB1B mRNA; lipopolysaccharide, E coli O55-B5 inhibits the reaction [2-Acetylaminofluorene results in increased expression of ABCB1B mRNA]; RELA protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1B mRNA]
CTD PMID:11020383, PMID:11170838, PMID:12801967, PMID:17070881, PMID:22084566 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of ABCC1 mRNA CTD PMID:12801967, PMID:17669244 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO 2-Acetylaminofluorene results in increased expression of ABCC10 mRNA CTD PMID:12566991 NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of ABCC2 mRNA
2-Acetylaminofluorene results in increased expression of ABCC2 mRNA; 2-Acetylaminofluorene results in increased expression of ABCC2 protein
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]
CTD PMID:10691972, PMID:16381673, PMID:16426233 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of ABCC3 mRNA; 2-Acetylaminofluorene results in increased expression of ABCC3 protein CTD PMID:10691972, PMID:12801967 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression
increases activity
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of ABCG2 mRNA
2-Acetylaminofluorene results in increased activity of ABCG2 protein
2-Acetylaminofluorene results in increased expression of ABCG2 mRNA; 2-Acetylaminofluorene results in increased expression of ABCG2 protein
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCG2 mRNA]
CTD PMID:12819005, PMID:16381673, PMID:17538966, PMID:17669244, PMID:27475308 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of ACAA2 mRNA CTD PMID:14656948 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acot9 acyl-CoA thioesterase 9 increases expression EXP 2-Acetylaminofluorene results in increased expression of ACOT9 mRNA CTD PMID:21784091 NCBI chr  X:43,543,069...43,592,200
Ensembl chr  X:43,543,070...43,592,200
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of AEN mRNA CTD PMID:17070881, PMID:21607683, PMID:22584684 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Afp alpha-fetoprotein multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] affects the expression of AFP protein; [2-Acetylaminofluorene co-treated with Choline deficiency] results in increased expression of AFP protein
2-Acetylaminofluorene results in increased expression of AFP mRNA; 2-Acetylaminofluorene results in increased expression of AFP protein
CTD PMID:6187438, PMID:11350689, PMID:11813887, PMID:15133858, PMID:17538966 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO 2-Acetylaminofluorene results in increased expression of AHR mRNA CTD PMID:25224404 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak1 adenylate kinase 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of AK1 mRNA CTD PMID:17317680 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO 2-Acetylaminofluorene results in increased expression of AKR1B3 mRNA CTD PMID:17317680 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AKR1B10 mRNA
2-Acetylaminofluorene results in increased expression of AKR1B10 mRNA
CTD PMID:14656948, PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-Acetylaminofluorene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein; [2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA
2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein; Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:11960367, PMID:17303067 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Choline deficiency] results in increased expression of ALB protein
2-Acetylaminofluorene results in increased expression of ALB protein
CTD PMID:6187438, PMID:15133858 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-Acetylaminofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881, PMID:22584684 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression EXP 2-Acetylaminofluorene results in increased expression of ALDH1A3 mRNA CTD PMID:22584684 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 2-Acetylaminofluorene results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:240,584,233...240,601,843
Ensembl chr 1:240,562,423...240,601,744
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ALDH3A1 mRNA] CTD PMID:17317680 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein]; Tocotrienols affects the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein] CTD PMID:15548946, PMID:15554553 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anapc11 anaphase promoting complex subunit 11 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ANAPC11 mRNA CTD PMID:22584684 NCBI chr10:109,774,779...109,785,877
Ensembl chr10:109,774,878...109,785,877
JBrowse link
G Anxa3 annexin A3 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of ANXA3 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ANXA3 mRNA]
[Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of ANXA3 mRNA
CTD PMID:17317680, PMID:18071240 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa8 annexin A8 increases expression ISO 2-Acetylaminofluorene results in increased expression of ANXA8 mRNA CTD PMID:17317680 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of AOX1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AOX1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apod apolipoprotein D decreases expression ISO 2-Acetylaminofluorene results in decreased expression of APOD mRNA CTD PMID:20713471 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Aqp5 aquaporin 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of AQP5 mRNA CTD PMID:17187413 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Areg amphiregulin increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of AREG mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of AREG mRNA]
CTD PMID:17317680 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ASGR1 mRNA CTD PMID:17187413 NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-Acetylaminofluorene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of BAX mRNA]
2-Acetylaminofluorene results in increased expression of BAX mRNA
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein]
CTD PMID:11915028, PMID:17070881, PMID:17317680, PMID:19167416, PMID:21607683, PMID:22584684 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein]
2-Acetylaminofluorene results in increased expression of BCL2 mRNA
CTD PMID:11915028, PMID:19167416, PMID:22213190 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein]
2-Acetylaminofluorene results in increased expression of BCL2L1 mRNA
CTD PMID:11915028, PMID:21607683 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of BIRC5 mRNA CTD PMID:19167416, PMID:22213190 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression EXP 2-Acetylaminofluorene results in increased expression of BRCA1 mRNA CTD PMID:19167416 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of BTG2 mRNA CTD PMID:17070881, PMID:21607683 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of BZW1 mRNA CTD PMID:17317680 NCBI chr 9:65,279,675...65,293,471
Ensembl chr 9:65,279,675...65,291,651
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP 2-Acetylaminofluorene results in decreased expression of C4BPA mRNA CTD PMID:16510358 NCBI chr13:47,342,090...47,377,580
Ensembl chr13:47,342,079...47,377,703
JBrowse link
G C6 complement C6 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of C6 mRNA CTD PMID:22584684 NCBI chr 2:54,460,333...54,533,801
Ensembl chr 2:54,466,280...54,533,797
JBrowse link
G C7 complement C7 increases expression EXP 2-Acetylaminofluorene results in increased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,707,621...54,781,624
Ensembl chr 2:54,709,138...54,777,729
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CACNA2D1 mRNA CTD PMID:17187413 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CADM1 protein CTD PMID:17326163 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CAR2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAR2 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
EXP 2-Acetylaminofluorene inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of CASP3 protein]; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein] CTD PMID:12907702, PMID:23665045, PMID:26364502 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP7 protein] CTD PMID:23665045 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 increases activity
increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased activity of CASP9 protein
2-Acetylaminofluorene results in increased expression of CASP9 protein
Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]
CTD PMID:23665045, PMID:26364502 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of CAT protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of CAT protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein] CTD PMID:17761372, PMID:23665045, PMID:26364502 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cavin3 caveolae associated protein 3 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAVIN3 mRNA CTD PMID:14656948 NCBI chr 1:170,317,099...170,318,688
Ensembl chr 1:170,317,113...170,318,935
JBrowse link
G Cblc Cbl proto-oncogene C increases expression EXP 2-Acetylaminofluorene results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:80,699,321...80,716,146
Ensembl chr 1:80,699,323...80,716,146
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of CBR1 mRNA CTD PMID:21607683 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cck cholecystokinin decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CCK mRNA CTD PMID:22584684 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression EXP 2-Acetylaminofluorene affects the expression of CCL2 mRNA; 2-Acetylaminofluorene affects the expression of CCL2 protein CTD PMID:25051504 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP 2-Acetylaminofluorene results in increased expression of CCL7 protein CTD PMID:25051504 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of CCN2 mRNA; 2-Acetylaminofluorene results in increased expression of CCN2 protein
Iloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CCN2 mRNA]
CTD PMID:15940639 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CCNA2 protein CTD PMID:15158336 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
EXP 2-Acetylaminofluorene results in decreased expression of CCNB1 protein
2-Acetylaminofluorene results in increased expression of CCNB1 mRNA
CTD PMID:15158336, PMID:22584684 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of CCNB2 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CCNB2 mRNA]
CTD PMID:17317680, PMID:19167416, PMID:22584684 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA]
2-Acetylaminofluorene results in increased expression of CCND1 mRNA
CTD PMID:14633663, PMID:22584684 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 multiple interactions
decreases activity
EXP 2-Acetylaminofluorene inhibits the reaction [CDK2 protein binds to CCNE1 protein]; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA]
2-Acetylaminofluorene results in decreased activity of CCNE1 protein
CTD PMID:10708481, PMID:14633663 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccng1 cyclin G1 decreases expression
increases expression
EXP
ISO
2-Acetylaminofluorene results in decreased expression of CCNG1 mRNA
2-Acetylaminofluorene results in increased expression of CCNG1 mRNA
CTD PMID:17070881, PMID:17317680, PMID:19167416, PMID:21607683, PMID:22584684 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd276 Cd276 molecule increases expression EXP 2-Acetylaminofluorene results in increased expression of CD276 mRNA CTD PMID:17070881, PMID:21784091 NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP
IEP
2-Acetylaminofluorene results in increased expression of CD44 mRNA
2-Fluorenylacetamide increases CD44 mRNA in liver, and protein in liver and serum
CTD PMID:17187413, PMID:22584684, PMID:31966914 RGD:25823185 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDC37 mRNA; [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDC37 protein CTD PMID:16317707 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDCA3 mRNA CTD PMID:22584684 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdh13 cadherin 13 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDH13 mRNA CTD PMID:21784091 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh22 cadherin 22 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDH22 mRNA CTD PMID:17187413 NCBI chr 3:161,574,993...161,971,102
Ensembl chr 3:161,575,631...161,917,285
JBrowse link
G Cdh3 cadherin 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDH3 mRNA CTD PMID:17187413 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDK1 mRNA CTD PMID:19167416, PMID:22584684 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
EXP 2-Acetylaminofluorene inhibits the reaction [CDK2 protein binds to CCNE1 protein]; 2-Acetylaminofluorene results in decreased localization of and results in decreased phosphorylation of and results in decreased activity of CDK2 protein
2-Acetylaminofluorene results in decreased activity of CDK2 protein
CTD PMID:10708481, PMID:15158336 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases activity EXP 2-Acetylaminofluorene results in increased activity of CDK4 protein CTD PMID:15158336 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
EXP
ISO
2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of CDKN1A protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA]; pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]
2-Acetylaminofluorene results in increased expression of CDKN1A mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CDKN1A mRNA]
2-Acetylaminofluorene results in increased expression of CDKN1A mRNA; 2-Acetylaminofluorene results in increased expression of CDKN1A protein
CTD PMID:10708481, PMID:11003613, PMID:14633663, PMID:17070881, PMID:17317680, PMID:17582756, PMID:19167416, PMID:21607683, PMID:22213190, PMID:22584684 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP 2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]; Pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]] CTD PMID:17582756 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
increases expression
increases methylation
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA; [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A protein
2-Acetylaminofluorene results in increased expression of CDKN2A mRNA
2-Acetylaminofluorene results in increased methylation of CDKN2A gene; 2-Acetylaminofluorene results in increased methylation of CDKN2A promoter
CTD PMID:16317707, PMID:18204080, PMID:19167416, PMID:20188851, PMID:22213190 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of CDKN2B mRNA CTD PMID:17317680, PMID:22213190 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression EXP 2-Acetylaminofluorene results in increased expression of CDKN2C mRNA CTD PMID:22584684 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of CDKN3 mRNA CTD PMID:22213190, PMID:22584684 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CEBPA protein CTD PMID:20188851, PMID:21785164 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression
EXP 2-Acetylaminofluorene inhibits the reaction [CEBPB protein binds to HAMP promoter]
2-Acetylaminofluorene results in decreased expression of CEBPB protein
CTD PMID:21785164 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces3a carboxylesterase 3a increases expression ISO 2-Acetylaminofluorene results in increased expression of CES3 mRNA CTD PMID:20713471 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of CKMT1 mRNA CTD PMID:17317680 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Cldn4 claudin 4 increases expression EXP 2-Acetylaminofluorene results in increased expression of CLDN4 mRNA CTD PMID:17187413 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn7 claudin 7 increases expression EXP 2-Acetylaminofluorene results in increased expression of CLDN7 mRNA CTD PMID:17187413 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Clu clusterin multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CLU mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CLU mRNA CTD PMID:14656948, PMID:16158176 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase increases expression EXP 2-Acetylaminofluorene results in increased expression of CMAS protein CTD PMID:6331524 NCBI chr 4:176,994,129...177,012,445
Ensembl chr 4:176,994,129...177,012,444
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of COL17A1 mRNA] CTD PMID:17317680 NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705
JBrowse link
G Commd3 COMM domain containing 3 increases expression ISO 2-Acetylaminofluorene results in increased expression of COMMD3 mRNA CTD PMID:17317680 NCBI chr17:85,356,042...85,359,835
Ensembl chr17:85,356,042...85,359,833
JBrowse link
G Coq6 coenzyme Q6 monooxygenase multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of COQ6 mRNA CTD PMID:16158176 NCBI chr 6:108,076,393...108,087,782
Ensembl chr 6:108,076,306...108,087,696
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] affects the expression of CPS1 protein CTD PMID:11813887 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Crebbp CREB binding protein decreases expression EXP 2-Acetylaminofluorene results in decreased expression of CREBBP mRNA CTD PMID:22213190 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-Acetylaminofluorene results in increased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CRYL1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CRYL1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Csta cystatin A affects expression ISO 2-Acetylaminofluorene affects the expression of CSTA mRNA CTD PMID:27825931 NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of CX3CL1 mRNA CTD PMID:17187413 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 affects expression EXP 2-Acetylaminofluorene affects the expression of CXCL1 protein CTD PMID:25051504 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 affects expression EXP 2-Acetylaminofluorene affects the expression of CXCL10 protein CTD PMID:25051504 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCL12 protein
2-Acetylaminofluorene results in increased expression of CXCL12 mRNA; 2-Acetylaminofluorene results in increased expression of CXCL12 protein
CTD PMID:12626097, PMID:15579440 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects expression EXP 2-Acetylaminofluorene affects the expression of CXCL2 protein CTD PMID:25051504 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of CXCR4 mRNA
[2-Acetylaminofluorene co-treated with Carbon Tetrachloride] results in increased expression of CXCR4 protein
CTD PMID:12626097, PMID:15579440 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydrolysis
multiple interactions
increases expression
ISO
EXP
CYP1A1 results in increased hydrolysis of 2-Acetylaminofluorene
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP1A1 mRNA]
2-Acetylaminofluorene analog results in increased expression of CYP1A1 protein; 2-Acetylaminofluorene results in increased expression of CYP1A1 mRNA; 2-Acetylaminofluorene results in increased expression of CYP1A1 protein
CTD PMID:2334931, PMID:10445401, PMID:11888708, PMID:15916741, PMID:20713471, PMID:25224404 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression
decreases expression
multiple interactions
increases hydrolysis
increases activity
ISO
EXP
CYP1A2 protein affects the metabolism of 2-Acetylaminofluorene
2-Acetylaminofluorene results in increased expression of CYP1A2 protein
2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA
2-Acetylaminofluorene analog results in decreased expression of CYP1A2 protein; 2-Acetylaminofluorene results in decreased expression of CYP1A2 protein
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA]
CYP1A2 results in increased hydrolysis of 2-Acetylaminofluorene
CYP1A2 protein results in increased activity of 2-Acetylaminofluorene
CTD PMID:2334931, PMID:2655891, PMID:15450435, PMID:15916741, PMID:16381673, PMID:28245158 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA]
CTD PMID:17317680, PMID:20713471 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of CYP2A22 mRNA CTD PMID:21607683 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression
increases expression
EXP 2-Acetylaminofluorene analog results in decreased expression of CYP2B1 protein; 2-Acetylaminofluorene results in decreased expression of CYP2B1 protein
2-Acetylaminofluorene results in increased expression of CYP2B1 protein
CTD PMID:10445401, PMID:15916741 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 decreases expression EXP 2-Acetylaminofluorene analog results in decreased expression of CYP2B2 protein; 2-Acetylaminofluorene results in decreased expression of CYP2B2 protein CTD PMID:15916741 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 increases expression EXP 2-Acetylaminofluorene results in increased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein]
2-Acetylaminofluorene analog results in increased expression of CYP2E1 protein; 2-Acetylaminofluorene results in increased expression of CYP2E1 protein
CTD PMID:14656948, PMID:15916741, PMID:16158176, PMID:17393424, PMID:23665045 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of CYP3A2 protein CTD PMID:10445401 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA; 2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 protein
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP3A23-3A1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP3A23-3A1 mRNA; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA]; Trabectedin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA]
CTD PMID:12504080, PMID:14656948, PMID:16158176 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:14,559,806...14,574,345
Ensembl chr 7:14,529,482...14,574,361
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP7A1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dap death-associated protein multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of DAP mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of DAP mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO 2-Acetylaminofluorene results in increased expression of DDIT4L mRNA CTD PMID:21607683 NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of DDR1 mRNA CTD PMID:17187413 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Des desmin increases expression EXP 2-Acetylaminofluorene results in increased expression of DES mRNA CTD PMID:17187413 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) decreases activity EXP 2-Acetylaminofluorene results in decreased activity of DHODH protein CTD PMID:6331524 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of DLK1 mRNA; 2-Acetylaminofluorene results in increased expression of DLK1 protein CTD PMID:15567716, PMID:17187413, PMID:17538966 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of DMP1 mRNA CTD PMID:17317680 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression
increases expression
EXP 2-Acetylaminofluorene results in decreased expression of E2F1 protein
2-Acetylaminofluorene results in increased expression of E2F1 mRNA
CTD PMID:15158336, PMID:19167416, PMID:22213190 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f3 E2F transcription factor 3 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of E2F3 protein CTD PMID:15158336, PMID:19167416 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G E2f4 E2F transcription factor 4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of E2F4 protein CTD PMID:15158336 NCBI chr19:37,252,828...37,260,239
Ensembl chr19:37,252,843...37,260,239
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO 2-Acetylaminofluorene results in increased expression of EDA2R mRNA CTD PMID:21607683 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Egf epidermal growth factor decreases localization
multiple interactions
EXP 2-Acetylaminofluorene results in decreased localization of EGF protein
2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein]
CTD PMID:10900465 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
EXP 2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein]
2-Acetylaminofluorene results in decreased expression of EGFR mRNA
CTD PMID:10900465, PMID:22213190 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of EGR1 mRNA CTD PMID:19167416 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of EI24 mRNA] CTD PMID:17317680 NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959
JBrowse link
G Emp2 epithelial membrane protein 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of EMP2 mRNA CTD PMID:21607683 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of ENC1 mRNA CTD PMID:21607683 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eno1 enolase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of ENO1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of ENO1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 2-Acetylaminofluorene results in increased expression of EPCAM mRNA CTD PMID:17070881, PMID:17187413 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Epha1 Eph receptor A1 increases expression ISO 2-Acetylaminofluorene results in increased expression of EPHA1 mRNA CTD PMID:17317680 NCBI chr 4:71,749,100...71,763,681
Ensembl chr 4:71,749,242...71,763,679
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881, PMID:17317680, PMID:21607683 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of ERBB2 protein CTD PMID:11350689 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ESR1 mRNA CTD PMID:19167416 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO 2-Acetylaminofluorene results in increased expression of EXOC4 mRNA CTD PMID:21607683 NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994
JBrowse link
G Fam110a family with sequence similarity 110, member A increases expression ISO 2-Acetylaminofluorene results in increased expression of FAM110A mRNA CTD PMID:21607683 NCBI chr 3:147,476,580...147,487,170
Ensembl chr 3:147,476,580...147,487,170
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of FAS mRNA CTD PMID:17070881, PMID:22584684 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbxw9 F-box and WD repeat domain containing 9 increases expression ISO 2-Acetylaminofluorene results in increased expression of FBXW9 mRNA CTD PMID:21607683 NCBI chr19:26,173,771...26,180,675
Ensembl chr19:26,173,771...26,180,675
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:15,697,292...16,862,873 JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 affects expression EXP 2-Acetylaminofluorene affects the expression of FLT3 mRNA CTD PMID:18031378 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570
JBrowse link
G Fn1 fibronectin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of FN1 mRNA CTD PMID:15940639 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of FOS protein; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of FOS protein] CTD PMID:17696247 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of FTH1 protein CTD PMID:21785164 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of G6PC protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of G6PC protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of G6PC protein] CTD PMID:15554553 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gaa glucosidase, alpha, acid increases expression ISO 2-Acetylaminofluorene results in increased expression of GAA mRNA CTD PMID:17317680 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of GAS2L3 mRNA CTD PMID:20713471 NCBI chr 7:29,963,129...29,996,021
Ensembl chr 7:29,959,597...29,986,163
JBrowse link
G Gcgr glucagon receptor multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCGR mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GCGR mRNA CTD PMID:14656948, PMID:16158176 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of GCLC mRNA
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLC mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GCLC mRNA
CTD PMID:14656948, PMID:16158176, PMID:16426233 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLM mRNA CTD PMID:16158176 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO 2-Acetylaminofluorene results in increased expression of GDF15 mRNA CTD PMID:21607683 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of GGT1 mRNA
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GGT1 protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GGT1 protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GGT1 protein]
CTD PMID:15554553, PMID:17187413 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of GJA1 mRNA; 2-Acetylaminofluorene results in increased expression of GJA1 protein CTD PMID:15133858, PMID:17187413 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of GJB1 mRNA CTD PMID:2559087 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of GJB2 mRNA CTD PMID:22213190 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO 2-Acetylaminofluorene results in increased expression of GLRX3 mRNA CTD PMID:17317680 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gpc3 glypican 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of GPC3 mRNA CTD PMID:17187413 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GPX2 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of GRIA3 mRNA CTD PMID:17070881, PMID:21607683 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of GRINA mRNA CTD PMID:21607683 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
decreases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSR mRNA; Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of GSR protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein] CTD PMID:16158176, PMID:23665045, PMID:26364502 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression ISO 2-Acetylaminofluorene results in increased expression of GSS mRNA CTD PMID:17317680 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of GSTA1 mRNA; 2-Acetylaminofluorene results in increased expression of GSTA2 mRNA
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTA2 mRNA
CTD PMID:14656948, PMID:16158176, PMID:17317680 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO 2-Acetylaminofluorene results in increased expression of GSTA1 mRNA; 2-Acetylaminofluorene results in increased expression of GSTA2 mRNA CTD PMID:17317680 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GSTP1 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GSTP1 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 protein; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GSTP1 protein]; herbal compound 861 inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 mRNA]; herbal compound 861 inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 mRNA]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of GSTP1 protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of GSTP1 protein]
2-Acetylaminofluorene results in increased expression of GSTP1 mRNA; 2-Acetylaminofluorene results in increased expression of GSTP1 protein
CTD PMID:12497209, PMID:12781041, PMID:12907702, PMID:15554553, PMID:17393424, PMID:18271918, PMID:21785164, PMID:22213190 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of GTSE1 mRNA CTD PMID:21607683 NCBI chr 7:126,736,416...126,753,221
Ensembl chr 7:126,736,732...126,753,220
JBrowse link
G H2ax H2A.X variant histone increases expression EXP 2-Acetylaminofluorene results in increased expression of H2AX protein CTD PMID:26338220 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of HADHA mRNA CTD PMID:16158176 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
EXP 2-Acetylaminofluorene inhibits the reaction [CEBPB protein binds to HAMP promoter]
2-Acetylaminofluorene results in decreased expression of HAMP mRNA
CTD PMID:21785164 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hebp2 heme binding protein 2 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of HEBP2 mRNA] CTD PMID:17317680 NCBI chr 1:13,713,152...13,719,970
Ensembl chr 1:13,714,440...13,719,829
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of HMGCR mRNA; beta-ionone promotes the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of HMGCR mRNA] CTD PMID:20435455 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of HMOX1 mRNA CTD PMID:22584684 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP 2-Acetylaminofluorene results in increased expression of HRAS protein CTD PMID:11350689 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197
Ensembl chr13:2,412,363...2,431,197
JBrowse link
G Ica1 islet cell autoantigen 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of ICA1 mRNA CTD PMID:21784091 NCBI chr 4:34,635,509...34,780,187
Ensembl chr 4:34,635,506...34,780,193
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO 2-Acetylaminofluorene results in increased expression of ID1 mRNA CTD PMID:15120964 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ifna1 interferon, alpha 1 multiple interactions EXP IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA]; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA]; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA] CTD PMID:14633663 NCBI chr 5:106,951,822...106,952,908
Ensembl chr 5:106,952,082...106,952,792
JBrowse link
G Ifna2 interferon alpha 2 multiple interactions EXP IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein]; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TGFB1 protein]; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD2 protein]; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein] CTD PMID:11915028, PMID:15368444 NCBI chr 5:107,416,117...107,416,695
Ensembl chr 5:107,416,117...107,416,695
JBrowse link
G Ifng interferon gamma multiple interactions EXP 2-Acetylaminofluorene inhibits the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein] CTD PMID:14736494 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of IGF2 mRNA CTD PMID:22213190 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO 2-Acetylaminofluorene results in decreased expression of IGFALS mRNA CTD PMID:21607683 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases activity ISO 2-Acetylaminofluorene results in increased activity of IKBKB protein CTD PMID:11960367 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 affects expression EXP 2-Acetylaminofluorene affects the expression of IL10 protein CTD PMID:25051504 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B increases expression EXP 2-Acetylaminofluorene results in increased expression of IL12B protein CTD PMID:25051504 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects expression
increases expression
ISO
EXP
2-Acetylaminofluorene inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
2-Acetylaminofluorene affects the expression of IL1B mRNA
2-Acetylaminofluorene results in increased expression of IL1B protein
CTD PMID:14670622, PMID:25051504 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 2-Acetylaminofluorene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il33 interleukin 33 increases expression ISO 2-Acetylaminofluorene results in increased expression of IL33 mRNA CTD PMID:17317680 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il5 interleukin 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of IL5 protein CTD PMID:25051504 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of IL6 protein CTD PMID:25051504 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb4 integrin subunit beta 4 increases expression ISO 2-Acetylaminofluorene results in increased expression of ITGB4 mRNA CTD PMID:17317680 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of JUN protein; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of JUN protein] CTD PMID:17696247 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kdm6a lysine demethylase 6A decreases expression EXP 2-Acetylaminofluorene results in decreased expression of KDM6A mRNA CTD PMID:22213190 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Kif11 kinesin family member 11 increases expression EXP 2-Acetylaminofluorene results in increased expression of KIF11 mRNA CTD PMID:22584684 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression EXP 2-Acetylaminofluorene results in increased expression of KIT protein CTD PMID:15133858 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Krt15 keratin 15 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of KRT15 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT15 mRNA]
CTD PMID:17317680 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt19 keratin 19 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of KRT19 mRNA; 2-Acetylaminofluorene results in increased expression of KRT19 protein
[Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of KRT19 protein
CTD PMID:15133858, PMID:17187413, PMID:17661067 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt20 keratin 20 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of KRT20 mRNA CTD PMID:17317680 NCBI chr10:87,342,514...87,351,045
Ensembl chr10:87,342,619...87,351,045
JBrowse link
G Krt23 keratin 23 multiple interactions
increases expression
ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT23 mRNA] CTD PMID:17317680 NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
JBrowse link
G Krt4 keratin 4 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of KRT4 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT4 mRNA]
CTD PMID:17317680 NCBI chr 7:143,517,562...143,523,522
Ensembl chr 7:143,518,010...143,523,503
JBrowse link
G Krt8 keratin 8 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of KRT8 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of KRT8 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lep leptin increases expression EXP 2-Acetylaminofluorene results in increased expression of LEP protein CTD PMID:25051504 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lig4 DNA ligase 4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of LIG4 mRNA CTD PMID:19167416 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G LOC100910526 sulfotransferase 1C2-like decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SULT1C2 mRNA CTD PMID:21607683 NCBI chr 9:4,820,678...4,834,271
Ensembl chr 9:4,807,717...4,834,335
JBrowse link
G LOC102550598 small proline-rich protein 2I-like increases expression ISO 2-Acetylaminofluorene results in increased expression of SPRR2G mRNA CTD PMID:17317680 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO 2-Acetylaminofluorene results in increased expression of LY6D mRNA CTD PMID:17317680 NCBI chr 7:115,993,304...115,994,812
Ensembl chr 7:115,993,301...115,994,783
JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression ISO 2-Acetylaminofluorene results in increased expression of LY6E mRNA CTD PMID:21607683 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of LYPD3 mRNA] CTD PMID:17317680 NCBI chr 1:81,499,856...81,504,306
Ensembl chr 1:81,499,821...81,504,318
JBrowse link
G Lzic leucine zipper and CTNNBIP1 domain containing increases expression ISO 2-Acetylaminofluorene results in increased expression of LZIC mRNA CTD PMID:21607683 NCBI chr 5:166,430,305...166,443,485
Ensembl chr 5:166,430,400...166,442,284
JBrowse link
G Mal mal, T-cell differentiation protein increases expression ISO 2-Acetylaminofluorene results in increased expression of MAL mRNA CTD PMID:17317680 NCBI chr 3:120,209,647...120,233,655
Ensembl chr 3:120,209,647...120,233,655
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP 2-Acetylaminofluorene affects the phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17546627 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mat1a methionine adenosyltransferase 1A affects acetylation
decreases expression
affects methylation
EXP 2-Acetylaminofluorene affects the acetylation of MAT1A exon; 2-Acetylaminofluorene affects the acetylation of MAT1A promoter
2-Acetylaminofluorene results in decreased expression of MAT1A mRNA
2-Acetylaminofluorene affects the methylation of MAT1A exon; 2-Acetylaminofluorene affects the methylation of MAT1A promoter
CTD PMID:22213190 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Matn2 matrilin 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of MATN2 mRNA; 2-Acetylaminofluorene results in increased expression of MATN2 protein CTD PMID:17513098 NCBI chr 7:72,985,832...73,210,093
Ensembl chr 7:72,985,495...73,207,695
JBrowse link
G Mbl2 mannose binding lectin 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of MBL2 mRNA CTD PMID:21607683 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein
2-Acetylaminofluorene results in increased expression of MDM2 mRNA; 2-Acetylaminofluorene results in increased expression of MDM2 protein
CTD PMID:11003613, PMID:19167416, PMID:21607683, PMID:22213190, PMID:22584684 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
decreases expression
EXP 2-Acetylaminofluorene results in increased expression of MGMT mRNA
2-Acetylaminofluorene results in decreased expression of MGMT mRNA
CTD PMID:17070881, PMID:22213190 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of MGST2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MGST2 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mir106b microRNA 106b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR106B mRNA CTD PMID:19167416 NCBI chr12:19,307,752...19,307,833
Ensembl chr12:19,307,752...19,307,833
JBrowse link
G Mir125b1 microRNA 125b-1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR125B-1 mRNA CTD PMID:19167416 NCBI chr 8:45,798,260...45,798,346
Ensembl chr 8:45,798,260...45,798,346
JBrowse link
G Mir130b microRNA 130b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR130B mRNA CTD PMID:19167416 NCBI chr11:88,129,773...88,129,854
Ensembl chr11:88,129,773...88,129,854
JBrowse link
G Mir132 microRNA 132 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR132 mRNA CTD PMID:19167416 NCBI chr10:62,014,995...62,015,095
Ensembl chr10:62,014,995...62,015,095
JBrowse link
G Mir146b microRNA 146b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR146B mRNA CTD PMID:19167416 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir155 microRNA 155 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR155 mRNA CTD PMID:19167416 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir17 microRNA 17 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR17; 2-Acetylaminofluorene results in increased expression of MIR17 mRNA CTD PMID:19167416, PMID:20188851 NCBI chr15:100,179,879...100,179,962
Ensembl chr15:100,179,879...100,179,962
JBrowse link
G Mir181b2 microRNA 181b-2 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR181B-2 mRNA CTD PMID:19167416 NCBI chr 3:23,151,455...23,151,542
Ensembl chr 3:23,151,455...23,151,542
JBrowse link
G Mir181c microRNA 181c decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR181C mRNA CTD PMID:19167416 NCBI chr19:25,290,211...25,290,316
Ensembl chr19:25,290,211...25,290,316
JBrowse link
G Mir185 microRNA 185 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR185 mRNA CTD PMID:19167416 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir18a microRNA 18a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR18A; 2-Acetylaminofluorene results in increased expression of MIR18A mRNA CTD PMID:19167416, PMID:20188851 NCBI chr15:100,180,015...100,180,110
Ensembl chr15:100,180,015...100,180,110
JBrowse link
G Mir200a microRNA 200a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR200A mRNA CTD PMID:19167416, PMID:22584684 NCBI chr 5:173,489,366...173,489,454 JBrowse link
G Mir200b microRNA 200b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR200B mRNA CTD PMID:19167416, PMID:22584684 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir200c microRNA 200c increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR200C mRNA CTD PMID:19167416 NCBI chr 4:157,236,786...157,236,854 JBrowse link
G Mir202 microRNA 202 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR202 mRNA CTD PMID:19167416 NCBI chr 1:212,295,630...212,295,701
Ensembl chr 1:212,295,630...212,295,701
JBrowse link
G Mir204 microRNA 204 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR204 mRNA CTD PMID:19167416 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir205 microRNA 205 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR205 mRNA CTD PMID:19167416 NCBI chr13:112,233,283...112,233,390
Ensembl chr13:112,233,283...112,233,390
JBrowse link
G Mir20a microRNA 20a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR20A; 2-Acetylaminofluorene results in increased expression of MIR20A mRNA CTD PMID:19167416, PMID:20188851 NCBI chr15:100,180,334...100,180,418
Ensembl chr15:100,180,334...100,180,418
JBrowse link
G Mir21 microRNA 21 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR21 mRNA CTD PMID:19167416 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir22 microRNA 22 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR22 mRNA CTD PMID:22213190 NCBI chr10:62,299,592...62,299,686
Ensembl chr10:62,299,592...62,299,686
JBrowse link
G Mir221 microRNA 221 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR221 mRNA CTD PMID:19167416 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir31 microRNA 31 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR31; 2-Acetylaminofluorene results in increased expression of MIR31 mRNA CTD PMID:19167416, PMID:20188851 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mir34a microRNA 34a increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR34A mRNA CTD PMID:19167416, PMID:22584684 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir3545 microRNA 3545 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR203 mRNA CTD PMID:22584684 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Mir410 microRNA 410 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR410 mRNA CTD PMID:19167416 NCBI chr 6:133,893,997...133,894,072
Ensembl chr 6:133,893,993...133,894,073
JBrowse link
G Mir429 microRNA 429 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR429 mRNA CTD PMID:19167416, PMID:22584684 NCBI chr 5:173,488,331...173,488,415
Ensembl chr 5:173,488,331...173,488,415
JBrowse link
G Mir490 microRNA 490 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR490 mRNA CTD PMID:19167416 NCBI chr 4:63,342,943...63,343,026
Ensembl chr 4:63,342,943...63,343,026
JBrowse link
G Mir93 microRNA 93 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR93; 2-Acetylaminofluorene results in increased expression of MIR93 mRNA CTD PMID:19167416, PMID:20188851 NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
JBrowse link
G Mir96 microRNA 96 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIR96 mRNA CTD PMID:19167416 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mir99a microRNA 99a decreases expression EXP 2-Acetylaminofluorene results in decreased expression of MIR99A mRNA CTD PMID:19167416, PMID:22584684 NCBI chr11:16,052,153...16,052,233
Ensembl chr11:16,052,153...16,052,233
JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP 2-Acetylaminofluorene results in increased expression of MIRLET7B mRNA CTD PMID:19167416 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression EXP 2-Acetylaminofluorene results in increased expression of MIRLET7C-1 mRNA CTD PMID:19167416 NCBI chr11:16,052,873...16,052,966
Ensembl chr11:16,052,868...16,052,975
JBrowse link
G Mirlet7i microRNA let-7i increases expression EXP 2-Acetylaminofluorene results in increased expression of MIRLET7I mRNA CTD PMID:19167416 NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MKI67 protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MKI67 protein]; Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]
2-Acetylaminofluorene results in increased expression of MKI67 mRNA
CTD PMID:15565650, PMID:17317680, PMID:17393424, PMID:23665045, PMID:26338220 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of MMP2 mRNA CTD PMID:18678246 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression EXP 2-Acetylaminofluorene results in increased expression of MMP9 mRNA CTD PMID:18678246 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
EXP Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein] CTD PMID:15565650 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mthfr methylenetetrahydrofolate reductase decreases expression
decreases methylation
EXP 2-Acetylaminofluorene results in decreased expression of MTHFR mRNA
2-Acetylaminofluorene results in decreased methylation of MTHFR promoter
CTD PMID:22213190 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression EXP 2-Acetylaminofluorene results in increased expression of MUC1 mRNA CTD PMID:17187413 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of MYBL1 mRNA CTD PMID:21607683 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases mutagenesis
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of MYC protein; Drugs, Chinese Herbal inhibits the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of MYC protein]
2-Acetylaminofluorene results in increased mutagenesis of MYC gene
2-Acetylaminofluorene results in increased expression of MYC protein
CTD PMID:11350689, PMID:17696247, PMID:19167416, PMID:20188851 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of NAMPT mRNA CTD PMID:22584684 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nat1 N-acetyltransferase 1 increases activity ISO NAT1 protein results in increased activity of 2-Acetylaminofluorene CTD PMID:15450435 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 increases activity ISO NAT2 protein results in increased activity of 2-Acetylaminofluorene CTD PMID:15450435 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Nek6 NIMA-related kinase 6 increases expression EXP 2-Acetylaminofluorene results in increased expression of NEK6 mRNA CTD PMID:22584684 NCBI chr 3:22,811,927...22,888,598
Ensembl chr 3:22,811,927...22,888,598
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
increases activity
ISO 2-Acetylaminofluorene results in increased expression of NFE2L2 mRNA
2-Acetylaminofluorene results in increased activity of NFE2L2 protein
CTD PMID:21607683, PMID:30114225 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases localization
ISO [RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]
2-Acetylaminofluorene results in increased localization of NFKB1 protein
Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased localization of NFKB1 protein]
CTD PMID:11960367, PMID:17303067 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein; Acetylcysteine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein]; S-Adenosylmethionine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein] CTD PMID:18404532 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions
increases degradation
EXP [2-Acetylaminofluorene results in increased abundance of Reactive Oxygen Species] which results in increased degradation of NFKBIB protein
2-Acetylaminofluorene results in increased degradation of NFKBIB protein
CTD PMID:11020383 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO 2-Acetylaminofluorene results in increased expression of TNFRSF10B mRNA CTD PMID:21607683 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Ninj1 ninjurin 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of NINJ1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NINJ1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NOS2 protein; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein] CTD PMID:23665045, PMID:26364502 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of NOS3 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of NOS3 mRNA]
CTD PMID:17317680 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of NOTCH1 mRNA CTD PMID:21607683 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit increases expression ISO 2-Acetylaminofluorene results in increased expression of NPRL2 mRNA CTD PMID:17317680 NCBI chr 8:116,297,950...116,301,123
Ensembl chr 8:116,297,950...116,301,122
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of NQO1 mRNA CTD PMID:21607683, PMID:22213190 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of NR1I2 mRNA
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23-3A1 mRNA]
NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCG2 mRNA]; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA]; NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A11 mRNA]
CTD PMID:12504080, PMID:16381673 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nudcd2 NudC domain containing 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of NUDCD2 mRNA CTD PMID:21607683 NCBI chr10:25,890,943...25,896,432
Ensembl chr10:25,890,943...25,896,432
JBrowse link
G Nudt7 nudix hydrolase 7 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of NUDT7 mRNA CTD PMID:21607683 NCBI chr19:46,455,745...46,470,070
Ensembl chr19:46,455,761...46,482,050
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 2-Acetylaminofluorene results in decreased expression of NUPR1 mRNA CTD PMID:17070881, PMID:22584684 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of NUSAP1 mRNA CTD PMID:22584684 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Ociad2 OCIA domain containing 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of OCIAD2 mRNA CTD PMID:17317680 NCBI chr14:37,432,999...37,449,425
Ensembl chr14:37,435,654...37,444,775
JBrowse link
G Olfm1 olfactomedin 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of OLFM1 mRNA CTD PMID:20713471 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Olr37 olfactory receptor 37 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:164,755,094...164,756,059 JBrowse link
G Osm oncostatin M increases expression EXP 2-Acetylaminofluorene results in increased expression of OSM mRNA CTD PMID:15743783, PMID:18678246 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Osmr oncostatin M receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of OSMR mRNA CTD PMID:15743783 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
JBrowse link
G Padi2 peptidyl arginine deiminase 2 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PADI2 mRNA] CTD PMID:17317680 NCBI chr 5:159,428,479...159,471,113
Ensembl chr 5:159,428,515...159,471,144
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PCK1 mRNA CTD PMID:16510358 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PCNA protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PCNA protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein] CTD PMID:16352317, PMID:17393424, PMID:19167416, PMID:23665045, PMID:26364502 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PDIA3 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PDIA3 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of PECAM1 mRNA CTD PMID:17187413 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Perp p53 apoptosis effector related to PMP22 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PERP mRNA] CTD PMID:17317680 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of PHLDA3 mRNA CTD PMID:17070881, PMID:21607683, PMID:22584684 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of PHYH mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of PHYH mRNA CTD PMID:14656948, PMID:16158176 NCBI chr17:77,287,580...77,304,482
Ensembl chr17:77,287,188...77,304,530
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis EXP 2-Acetylaminofluorene results in increased mutagenesis of PIGA CTD PMID:22923490 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PKD1 mRNA CTD PMID:22584684 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP 2-Acetylaminofluorene results in increased expression of PKM mRNA; 2-Acetylaminofluorene results in increased expression of PKM protein CTD PMID:17538966 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Pkp1 plakophilin 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of PKP1 mRNA CTD PMID:17317680 NCBI chr13:52,705,174...52,753,089
Ensembl chr13:52,705,174...52,752,997
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of PLK2 mRNA CTD PMID:21607683 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of PMAIP1 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PMAIP1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PMAIP1 mRNA]
CTD PMID:17317680, PMID:19167416 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Polk DNA polymerase kappa increases expression ISO 2-Acetylaminofluorene results in increased expression of POLK mRNA CTD PMID:21607683 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP 2-Acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of PRC1 mRNA CTD PMID:19167416 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prkch protein kinase C, eta multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PRKCH mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PRKCH mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 6:96,479,243...96,677,368
Ensembl chr 6:96,479,430...96,676,225
JBrowse link
G Prom1 prominin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of PROM1 mRNA CTD PMID:17187413 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Prox1 prospero homeobox 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PROX1 mRNA CTD PMID:22213190 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 increases expression
multiple interactions
EXP 2-Acetylaminofluorene results in increased expression of PSMD10 protein
RB1 protein affects the reaction [2-Acetylaminofluorene results in increased expression of PSMD10 protein]
CTD PMID:16448463 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of PSRC1 mRNA CTD PMID:21607683 NCBI chr 2:211,176,437...211,181,078
Ensembl chr 2:211,176,556...211,181,123
JBrowse link
G Pten phosphatase and tensin homolog decreases expression EXP 2-Acetylaminofluorene results in decreased expression of PTEN protein CTD PMID:19167416 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PTGR1 mRNA CTD PMID:16158176 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PTGS2 protein; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein] CTD PMID:23665045, PMID:26364502 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptn pleiotrophin increases expression EXP 2-Acetylaminofluorene results in increased expression of PTN mRNA CTD PMID:12057922 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 increases expression ISO 2-Acetylaminofluorene results in increased expression of PTP4A3 mRNA CTD PMID:17317680 NCBI chr 7:114,969,699...115,002,902
Ensembl chr 7:114,997,103...115,002,902
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression EXP 2-Acetylaminofluorene results in increased expression of PTPRC mRNA CTD PMID:17187413 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression EXP 2-Acetylaminofluorene results in increased expression of PTTG1 mRNA CTD PMID:19167416 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Pvt1 Pvt1 oncogene increases expression ISO 2-Acetylaminofluorene results in increased expression of PVT1 mRNA CTD PMID:21607683 NCBI chr 7:102,648,394...102,871,316 JBrowse link
G Rac1 Rac family small GTPase 1 increases activity
multiple interactions
ISO 2-Acetylaminofluorene results in increased activity of RAC1 protein
[2-Acetylaminofluorene results in increased activity of RAC1 protein] which results in increased expression of ABCB1 mRNA
CTD PMID:11960367 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rassf1 Ras association domain family member 1 increases methylation EXP 2-Acetylaminofluorene results in increased methylation of RASSF1 promoter CTD PMID:20188851 NCBI chr 8:116,307,149...116,318,289
Ensembl chr 8:116,307,141...116,318,289
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects phosphorylation
multiple interactions
EXP 2-Acetylaminofluorene affects the phosphorylation of RB1 protein
2-Acetylaminofluorene results in increased expression of and results in increased phosphorylation of RB1 protein; RB1 protein affects the reaction [2-Acetylaminofluorene results in increased expression of PSMD10 protein]
CTD PMID:15158336, PMID:16448463 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbx1 ring-box 1 increases expression ISO 2-Acetylaminofluorene results in increased expression of RBX1 mRNA CTD PMID:17317680 NCBI chr 7:122,700,849...122,710,907
Ensembl chr 7:122,700,854...122,709,935
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
increases expression
multiple interactions
increases localization
ISO
EXP
2-Acetylaminofluorene results in increased activity of RELA protein
2-Acetylaminofluorene results in increased expression of RELA protein
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; RELA protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1B mRNA]
2-Acetylaminofluorene results in increased localization of RELA protein
[RELA protein binds to NFKB1 protein] affects the reaction [2-Acetylaminofluorene results in increased expression of ABCB1 mRNA]
2-Acetylaminofluorene inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased localization of RELA protein]
CTD PMID:11020383, PMID:11960367, PMID:14670622, PMID:17303067, PMID:26364502 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rgn regucalcin multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of RGN mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of RGN mRNA CTD PMID:14656948, PMID:16158176 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of RGS2 mRNA CTD PMID:22584684 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of RHBDF2 mRNA CTD PMID:21607683 NCBI chr10:105,573,759...105,600,885
Ensembl chr10:105,573,752...105,600,913
JBrowse link
G Rhob ras homolog family member B increases expression EXP 2-Acetylaminofluorene results in increased expression of RHOB mRNA CTD PMID:22584684 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 2-Acetylaminofluorene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:51,465,148...51,485,562
Ensembl chr15:51,465,148...51,485,692
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of RIPK1 mRNA CTD PMID:22584684 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 increases expression ISO 2-Acetylaminofluorene results in increased expression of RIPK3 mRNA CTD PMID:17317680 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
G Ripk4 receptor-interacting serine-threonine kinase 4 increases expression ISO 2-Acetylaminofluorene results in increased expression of RIPK4 mRNA CTD PMID:21607683 NCBI chr11:38,251,991...38,274,234
Ensembl chr11:38,251,955...38,274,217
JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression EXP 2-Acetylaminofluorene results in increased expression of ROS1 mRNA CTD PMID:17187413 NCBI chr20:33,100,190...33,323,544
Ensembl chr20:33,100,191...33,323,367
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of RPLP0 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of RPLP0 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr12:46,791,528...46,794,797
Ensembl chr12:46,791,528...46,794,797
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog multiple interactions
increases expression
decreases expression
ISO
EXP
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of RPRM mRNA]
2-Acetylaminofluorene results in increased expression of RPRM mRNA
2-Acetylaminofluorene results in decreased expression of RPRM mRNA
CTD PMID:17317680, PMID:19167416, PMID:22584684 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO 2-Acetylaminofluorene results in increased expression of RPS27L mRNA CTD PMID:17317680 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression ISO 2-Acetylaminofluorene results in increased expression of RRM1 mRNA CTD PMID:17317680 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO 2-Acetylaminofluorene results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of RSAD2 mRNA CTD PMID:20713471 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO 2-Acetylaminofluorene results in increased expression of S100A11 mRNA CTD PMID:17317680 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G S100a14 S100 calcium binding protein A14 increases expression ISO 2-Acetylaminofluorene results in increased expression of S100A14 mRNA CTD PMID:17317680 NCBI chr 2:189,913,433...189,919,947 JBrowse link
G Scarb2 scavenger receptor class B, member 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of SCARB2 mRNA CTD PMID:17317680 NCBI chr14:17,064,173...17,115,620
Ensembl chr14:17,064,353...17,115,963
JBrowse link
G Scpep1 serine carboxypeptidase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of SCPEP1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of SCPEP1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr10:76,230,371...76,263,866
Ensembl chr10:76,230,373...76,263,866
JBrowse link
G Sctr secretin receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of SCTR mRNA CTD PMID:17187413 NCBI chr13:36,039,241...36,090,515
Ensembl chr13:36,039,283...36,090,530
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-Acetylaminofluorene results in increased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Serpinb5 serpin family B member 5 increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of SERPINB5 mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of SERPINB5 mRNA]
CTD PMID:17317680 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SERPINF1 mRNA CTD PMID:21607683 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sesn2 sestrin 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of SESN2 mRNA CTD PMID:21607683 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sfn stratifin increases expression EXP 2-Acetylaminofluorene results in increased expression of SFN mRNA CTD PMID:19167416, PMID:22213190 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sirt1 sirtuin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of SIRT1 protein CTD PMID:19167416 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc15a5 solute carrier family 15, member 5 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SLC15A5 mRNA CTD PMID:21607683 NCBI chr 4:171,970,620...172,063,391
Ensembl chr 4:171,970,620...172,063,391
JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of SLC25A4 mRNA] CTD PMID:17317680 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc2a8 solute carrier family 2 member 8 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SLC2A8 mRNA] CTD PMID:17317680 NCBI chr 3:12,020,227...12,029,920
Ensembl chr 3:12,020,229...12,029,877
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of SLC40A1 mRNA CTD PMID:21785164 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of SLCO1A4 mRNA CTD PMID:16158176 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of SLCO1B2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of SLCO1B2 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Smad2 SMAD family member 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD2 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD2 protein] CTD PMID:15368444 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein] CTD PMID:15368444 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SMAD4 mRNA CTD PMID:22213190 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smo smoothened, frizzled class receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of SMO mRNA CTD PMID:17187413 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Sncg synuclein, gamma increases expression EXP 2-Acetylaminofluorene results in increased expression of SNCG mRNA CTD PMID:22213190 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Sntg2 syntrophin, gamma 2 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of SNTG2 mRNA CTD PMID:21607683 NCBI chr 6:49,123,084...49,324,530
Ensembl chr 6:49,123,084...49,324,450
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of SOCS1 mRNA CTD PMID:22213190 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of SOD1 protein CTD PMID:17761372 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of and results in increased activity of SOD2 protein; O-(Chloroacetylcarbamoyl)fumagillol inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of and results in increased activity of SOD2 protein] CTD PMID:17761372 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox4 SRY-box transcription factor 4 increases expression EXP 2-Acetylaminofluorene results in increased expression of SOX4 mRNA CTD PMID:22584684 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO 2-Acetylaminofluorene results in increased expression of SPRR1A mRNA CTD PMID:17317680 NCBI chr 2:192,669,143...192,671,059
Ensembl chr 2:192,669,143...192,671,059
JBrowse link
G Sprr2f small proline rich protein 2F increases expression
multiple interactions
ISO 2-Acetylaminofluorene results in increased expression of SPRR2F mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SPRR2F mRNA]
CTD PMID:17317680 NCBI chr 2:192,604,978...192,605,208 JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 increases expression ISO 2-Acetylaminofluorene results in increased expression of SPTLC2 mRNA CTD PMID:17317680 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sst somatostatin increases expression EXP 2-Acetylaminofluorene results in increased expression of SST protein CTD PMID:16534498 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO 2-Acetylaminofluorene results in decreased expression of ST3GAL3 mRNA CTD PMID:21607683 NCBI chr 5:136,765,309...136,965,642
Ensembl chr 5:136,766,208...136,965,191
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 increases expression EXP 2-Acetylaminofluorene results in increased expression of ST3GAL5 protein CTD PMID:6331524 NCBI chr 4:99,937,499...99,999,905
Ensembl chr 4:99,937,558...99,999,902
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein; Dexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein] CTD PMID:12957465 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Steap3 STEAP3 metalloreductase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of STEAP3 mRNA CTD PMID:22584684 NCBI chr13:36,257,220...36,274,144
Ensembl chr13:36,257,112...36,290,531
JBrowse link
G Stmn1 stathmin 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of STMN1 mRNA CTD PMID:22584684 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Sulf2 sulfatase 2 increases expression EXP
ISO
2-Acetylaminofluorene results in increased expression of SULF2 mRNA CTD PMID:17070881, PMID:21607683 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of SULT1E1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Taldo1 transaldolase 1 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TALDO1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TALDO1 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tceal9 transcription elongation factor A like 9 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TCEAL9 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TCEAL9 mRNA CTD PMID:14656948, PMID:16158176 NCBI chr  X:106,791,333...106,794,667
Ensembl chr  X:106,791,333...106,794,657
JBrowse link
G Tes testin LIM domain protein increases expression EXP 2-Acetylaminofluorene results in increased expression of TES mRNA CTD PMID:21784091 NCBI chr 4:44,321,883...44,360,407
Ensembl chr 4:44,321,883...44,360,405
JBrowse link
G Tf transferrin decreases expression EXP 2-Acetylaminofluorene results in decreased expression of TF mRNA CTD PMID:16510358 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TFF1 mRNA] CTD PMID:17317680 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tff3 trefoil factor 3 increases expression EXP 2-Acetylaminofluorene results in increased expression of TFF3 mRNA CTD PMID:22213190 NCBI chr20:9,850,800...9,855,481
Ensembl chr20:9,850,803...9,855,481
JBrowse link
G Tfrc transferrin receptor increases expression EXP 2-Acetylaminofluorene results in increased expression of TFRC mRNA CTD PMID:21785164 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TGFB1 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TGFB1 protein]
2-Acetylaminofluorene results in increased expression of TGFB1 mRNA
CTD PMID:15368444, PMID:15940639 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thrb thyroid hormone receptor beta increases activity ISO 2-Acetylaminofluorene results in increased activity of THRB protein CTD PMID:31077750 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Thy1 Thy-1 cell surface antigen increases expression EXP 2-Acetylaminofluorene results in increased expression of THY1 protein CTD PMID:17576600 NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 2-Acetylaminofluorene results in increased expression of TIMP1 mRNA CTD PMID:18678246 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tkt transketolase multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TKT mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TKT mRNA CTD PMID:14656948, PMID:16158176 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tmem134 transmembrane protein 134 increases expression ISO 2-Acetylaminofluorene results in increased expression of TMEM134 mRNA CTD PMID:17317680 NCBI chr 1:219,374,005...219,383,365
Ensembl chr 1:219,374,060...219,379,557
JBrowse link
G Tmem184c transmembrane protein 184C increases expression EXP 2-Acetylaminofluorene results in increased expression of TMEM184C mRNA CTD PMID:21784091 NCBI chr19:34,041,128...34,057,165
Ensembl chr19:34,041,219...34,057,159
JBrowse link
G Tmem43 transmembrane protein 43 increases expression ISO 2-Acetylaminofluorene results in increased expression of TMEM43 mRNA CTD PMID:21607683 NCBI chr 4:123,118,468...123,133,610
Ensembl chr 4:123,118,468...123,133,609
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TNF protein; Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of TNF protein] CTD PMID:18271918, PMID:23665045, PMID:25051504 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP 2-Acetylaminofluorene results in increased expression of TOP2A mRNA CTD PMID:22584684 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
increases response to substance
multiple interactions
EXP
ISO
2-Acetylaminofluorene results in increased expression of TP53 protein
2-Acetylaminofluorene results in increased expression of TRP53 protein
2-Acetylaminofluorene results in decreased expression of TP53 protein
TRP53 protein modified form results in increased susceptibility to 2-Acetylaminofluorene
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of BAX mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CCNB2 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CDKN1A mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of EI24 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PERP mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of PMAIP1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of RPRM mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of SERPINB5 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of ZMAT3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of CYP4F15 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of MEG3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of SLC25A4 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of TTR mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ALDH3A1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of ANXA3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of AREG mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of COL17A1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of HEBP2 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT15 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT23 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of KRT4 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of LYPD3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of NOS3 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PADI2 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PMAIP1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SLC2A8 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of SPRR2F mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TFF1 mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TSHB mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TUBA1C mRNA]; TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of UBE2C mRNA]
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of TP53 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of TP53 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein]; Vanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein]
CTD PMID:7728945, PMID:9667752, PMID:10708481, PMID:11003613, PMID:11915028, PMID:12888115, PMID:14633663, PMID:15565650, PMID:17317680, PMID:19167416, PMID:23665045 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 multiple interactions
increases expression
EXP
ISO
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of TRP53INP1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of TRP53INP1 mRNA
2-Acetylaminofluorene results in increased expression of TP53INP1 mRNA
2-Acetylaminofluorene results in increased expression of TRP53INP1 mRNA
CTD PMID:14656948, PMID:16158176, PMID:21607683, PMID:22584684 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tp73 tumor protein p73 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of TP73 mRNA CTD PMID:22213190 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions EXP [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TRPM2 mRNA CTD PMID:16158176 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15089088 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TSHB mRNA] CTD PMID:17317680 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Ttr transthyretin multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in decreased expression of TTR mRNA] CTD PMID:17317680 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tuba1c tubulin, alpha 1C multiple interactions ISO TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of TUBA1C mRNA] CTD PMID:17317680 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Tubb4b tubulin, beta 4B class IVb increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of TUBB4B mRNA CTD PMID:21607683, PMID:22584684 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP 2-Acetylaminofluorene results in increased expression of TUBB5 mRNA CTD PMID:22584684 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Tubb6 tubulin, beta 6 class V increases expression ISO 2-Acetylaminofluorene results in increased expression of TUBB6 mRNA CTD PMID:21607683 NCBI chr18:63,130,542...63,140,181
Ensembl chr18:63,130,542...63,140,181
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression
multiple interactions
ISO
EXP
2-Acetylaminofluorene results in increased expression of UBE2C mRNA
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of UBE2C mRNA]
CTD PMID:17317680, PMID:22584684 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2-Acetylaminofluorene analog CTD PMID:11375903 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO
EXP
2-Acetylaminofluorene results in increased expression of VCAM1 mRNA
2-Acetylaminofluorene results in increased expression of VCAM1 protein
CTD PMID:21607683, PMID:25051504 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
increases expression
EXP 2-Acetylaminofluorene results in decreased expression of VEGFA mRNA
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein]
CTD PMID:22213190, PMID:25051504, PMID:26364502 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP 2-Acetylaminofluorene results in increased expression of WEE1 mRNA CTD PMID:22584684 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Wwox WW domain-containing oxidoreductase decreases expression ISO 2-Acetylaminofluorene results in decreased expression of WWOX mRNA CTD PMID:21607683 NCBI chr19:46,761,353...47,695,247 JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions
EXP 2-Acetylaminofluorene results in increased activity of XDH protein
Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of XDH protein]
CTD PMID:23665045 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases response to substance ISO XPC protein results in decreased susceptibility to 2-Acetylaminofluorene CTD PMID:23153559 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ZEB1 protein CTD PMID:19167416 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 decreases expression EXP 2-Acetylaminofluorene results in decreased expression of ZEB2 protein CTD PMID:19167416 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
G Zmat3 zinc finger, matrin type 3 multiple interactions
increases expression
ISO
EXP
TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of ZMAT3 mRNA]
2-Acetylaminofluorene results in increased expression of ZMAT3 mRNA
CTD PMID:17070881, PMID:17317680, PMID:19167416, PMID:21607683, PMID:22584684 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link
2-nitrofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP 2-nitrofluorene results in increased expression of ABCB1A mRNA CTD PMID:22484513 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 2-nitrofluorene results in increased expression of ABCB1B mRNA CTD PMID:14600272, PMID:23052194 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP 2-nitrofluorene results in increased expression of ABCC3 mRNA CTD PMID:23052194 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Aco1 aconitase 1 increases expression EXP 2-nitrofluorene results in increased expression of ACO1 mRNA CTD PMID:15890375 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO 2-nitrofluorene binds to and results in increased activity of AHR protein CTD PMID:28186253 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP 2-nitrofluorene results in increased expression of AIF1 mRNA CTD PMID:14600272 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 2-nitrofluorene results in increased expression of AKR7A3 mRNA CTD PMID:14600272, PMID:22484513, PMID:23052194 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 2-nitrofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:14600272, PMID:22484513, PMID:23052194 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Anxa2 annexin A2 increases expression EXP 2-nitrofluorene results in increased expression of ANXA2 mRNA CTD PMID:14600272 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP 2-nitrofluorene results in increased expression of APEX1 mRNA CTD PMID:15890375 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B increases expression EXP 2-nitrofluorene results in increased expression of ARPC1B mRNA CTD PMID:14600272 NCBI chr12:11,252,300...11,265,849
Ensembl chr12:11,252,296...11,265,865
JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP 2-nitrofluorene results in increased expression of ATF3 mRNA CTD PMID:15890375 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 decreases expression EXP 2-nitrofluorene results in decreased expression of ATP5MC1 mRNA CTD PMID:14600272 NCBI chr10:83,895,941...83,898,640
Ensembl chr10:83,895,947...83,898,527
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 2-nitrofluorene results in increased expression of ATP6V1D mRNA CTD PMID:14600272, PMID:22484513, PMID:23052194 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 2-nitrofluorene results in increased expression of BAX mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513, PMID:23052194 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP 2-nitrofluorene results in decreased expression of BHMT mRNA CTD PMID:14600272 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP 2-nitrofluorene results in increased expression of BTG2 mRNA CTD PMID:14600272, PMID:15890375, PMID:23052194 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression EXP 2-nitrofluorene results in increased expression of CCDC86 mRNA CTD PMID:22484513 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Ccnb1 cyclin B1 increases expression EXP 2-nitrofluorene results in increased expression of CCNB1 mRNA CTD PMID:15890375 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP 2-nitrofluorene results in increased expression of CCND1 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 2-nitrofluorene results in increased expression of CCNG1 mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513, PMID:23052194 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP 2-nitrofluorene results in increased expression of CCT3 mRNA CTD PMID:15890375 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cd1d1 CD1d1 molecule decreases expression EXP 2-nitrofluorene results in decreased expression of CD1D1 mRNA CTD PMID:22484513 NCBI chr 2:186,330,298...186,333,805
Ensembl chr 2:186,330,298...186,333,805
JBrowse link
G Cd74 CD74 molecule increases expression EXP 2-nitrofluorene results in increased expression of CD74 mRNA CTD PMID:14600272 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP 2-nitrofluorene results in decreased expression of CDC20 mRNA CTD PMID:15890375 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP 2-nitrofluorene results in increased expression of CDK1 mRNA CTD PMID:15890375 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk16 cyclin-dependent kinase 16 increases expression EXP 2-nitrofluorene results in increased expression of CDK16 mRNA CTD PMID:15890375 NCBI chr  X:1,707,285...1,718,821
Ensembl chr  X:1,707,289...1,718,637
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP 2-nitrofluorene results in increased expression of CDK4 mRNA CTD PMID:15890375 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP 2-nitrofluorene results in increased expression of CDKN1A mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513, PMID:23052194 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP 2-nitrofluorene results in increased expression of CES2C mRNA CTD PMID:23052194 NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP 2-nitrofluorene results in increased expression of CES2 mRNA CTD PMID:14600272, PMID:22484513 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP 2-nitrofluorene results in increased expression of CGREF1 mRNA CTD PMID:14600272, PMID:15890375, PMID:23052194 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP 2-nitrofluorene results in increased expression of CGRRF1 mRNA CTD PMID:15890375 NCBI chr15:23,619,176...23,639,622
Ensembl chr15:23,619,123...23,639,628
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like increases expression EXP 2-nitrofluorene results in increased expression of CR1L mRNA CTD PMID:15890375, PMID:22484513 NCBI chr13:113,824,886...113,872,097
Ensembl chr13:113,824,892...113,872,097
JBrowse link
G Cryab crystallin, alpha B increases expression EXP 2-nitrofluorene results in increased expression of CRYAB mRNA CTD PMID:14600272 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cstb cystatin B increases expression EXP 2-nitrofluorene results in increased expression of CSTB mRNA CTD PMID:15890375 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctsd cathepsin D increases expression EXP 2-nitrofluorene results in increased expression of CTSD mRNA CTD PMID:15890375 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctss cathepsin S increases expression EXP 2-nitrofluorene results in increased expression of CTSS mRNA CTD PMID:14600272 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP 2-nitrofluorene results in increased expression of CXCL10 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects expression EXP 2-nitrofluorene affects the expression of CXCL3 mRNA CTD PMID:22484513 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP 2-nitrofluorene results in decreased expression of CYB5R3 mRNA CTD PMID:14600272 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2-nitrofluorene results in increased expression of CYP1A1 mRNA CTD PMID:23052194 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression
increases expression
EXP 2-nitrofluorene results in decreased expression of CYP2C12 mRNA
2-nitrofluorene results in increased expression of CYP2C12 mRNA
CTD PMID:23052194 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Dcn decorin increases expression EXP 2-nitrofluorene results in increased expression of DCN mRNA CTD PMID:14600272 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 2-nitrofluorene results in increased expression of DDAH1 mRNA CTD PMID:15890375 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddx21 DExD-box helicase 21 increases expression EXP 2-nitrofluorene results in increased expression of DDX21 mRNA CTD PMID:15890375 NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 decreases expression EXP 2-nitrofluorene results in decreased expression of DKC1 mRNA CTD PMID:15890375 NCBI chr  X:155,844,914...155,862,363
Ensembl chr  X:155,844,857...155,862,475
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP 2-nitrofluorene results in increased expression of DMBT1 mRNA CTD PMID:23052194 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP 2-nitrofluorene results in decreased expression of DPYD mRNA CTD PMID:15890375 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dus1l dihydrouridine synthase 1-like increases expression EXP 2-nitrofluorene results in increased expression of DUS1L mRNA CTD PMID:22484513 NCBI chr10:109,972,018...109,979,113
Ensembl chr10:109,972,037...109,979,712
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP 2-nitrofluorene results in decreased expression of DUSP6 mRNA CTD PMID:15890375 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP 2-nitrofluorene results in increased expression of DUT mRNA CTD PMID:15890375 NCBI chr 3:117,514,399...117,525,450
Ensembl chr 3:117,514,444...117,525,446
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma increases expression EXP 2-nitrofluorene results in increased expression of EEF1G mRNA CTD PMID:15890375 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 increases expression EXP 2-nitrofluorene results in increased expression of EEF2 mRNA CTD PMID:15890375 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP 2-nitrofluorene results in increased expression of EIF4EBP1 mRNA CTD PMID:15890375 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 2-nitrofluorene results in increased expression of EPHX1 mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Fam162a family with sequence similarity 162, member A increases expression EXP 2-nitrofluorene results in increased expression of FAM162A mRNA CTD PMID:15890375 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression EXP 2-nitrofluorene results in increased expression of FCGR3 mRNA CTD PMID:14600272 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression EXP 2-nitrofluorene results in increased expression of FKBP4 mRNA CTD PMID:15890375 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fn1 fibronectin 1 decreases expression EXP 2-nitrofluorene results in decreased expression of FN1 mRNA CTD PMID:15890375 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2-nitrofluorene results in increased expression of GADD45A mRNA CTD PMID:15890375 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gas6 growth arrest specific 6 decreases expression
increases expression
EXP 2-nitrofluorene results in decreased expression of GAS6 mRNA
2-nitrofluorene results in increased expression of GAS6 mRNA
CTD PMID:14600272, PMID:15890375, PMID:23052194 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP 2-nitrofluorene results in increased expression of GCLC mRNA CTD PMID:14600272, PMID:15890375 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP 2-nitrofluorene results in increased expression of GDF15 mRNA CTD PMID:14600272, PMID:15890375, PMID:23052194 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gls2 glutaminase 2 decreases expression EXP 2-nitrofluorene results in decreased expression of GLS2 mRNA CTD PMID:14600272 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP 2-nitrofluorene results in decreased expression of GNMT mRNA CTD PMID:14600272 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gpr108 G protein-coupled receptor 108 decreases expression EXP 2-nitrofluorene results in decreased expression of GPR108 mRNA CTD PMID:22484513 NCBI chr 9:9,704,300...9,714,767
Ensembl chr 9:9,704,346...9,714,755
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP 2-nitrofluorene results in increased expression of GRIA3 mRNA CTD PMID:22484513 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP 2-nitrofluorene results in increased expression of GRPEL1 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP 2-nitrofluorene results in increased expression of GSR mRNA CTD PMID:14600272, PMID:15890375 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression EXP 2-nitrofluorene results in increased expression of GSS mRNA CTD PMID:15890375 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP 2-nitrofluorene results in increased expression of GSTA2 mRNA CTD PMID:15890375 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of GSTA5 mRNA CTD PMID:14600272 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP 2-nitrofluorene results in increased expression of GSTP1 mRNA CTD PMID:23052194 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G H2ax H2A.X variant histone increases expression EXP 2-nitrofluorene results in increased expression of H2AX mRNA CTD PMID:15890375 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP 2-nitrofluorene results in increased expression of H2AZ1 mRNA CTD PMID:15890375 NCBI chr 2:243,105,224...243,107,333
Ensembl chr 2:243,105,674...243,106,956
JBrowse link
G Hdc histidine decarboxylase increases expression EXP 2-nitrofluorene results in increased expression of HDC mRNA CTD PMID:15890375 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases expression EXP 2-nitrofluorene results in increased expression of HECTD1 mRNA CTD PMID:22484513 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP 2-nitrofluorene results in increased expression of HMGB2 mRNA CTD PMID:15890375 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP 2-nitrofluorene results in increased expression of HMOX1 mRNA CTD PMID:15890375 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression EXP 2-nitrofluorene results in increased expression of HSF1 mRNA CTD PMID:15890375 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP 2-nitrofluorene results in increased expression of HSPA9 mRNA CTD PMID:15890375 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPB1 mRNA CTD PMID:15890375 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPE1 mRNA CTD PMID:15890375 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP 2-nitrofluorene results in increased expression of HSPH1 mRNA CTD PMID:15890375 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ide insulin degrading enzyme increases expression EXP 2-nitrofluorene results in increased expression of IDE mRNA CTD PMID:15890375 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP 2-nitrofluorene results in increased expression of IGFBP1 mRNA CTD PMID:15890375 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP 2-nitrofluorene results in decreased expression of IGFBP3 mRNA CTD PMID:15890375 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP 2-nitrofluorene results in increased expression of IRF1 mRNA CTD PMID:14600272 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Lama5 laminin subunit alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of LAMA5 mRNA CTD PMID:22484513 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Lgals3 galectin 3 increases expression EXP 2-nitrofluorene results in increased expression of LGALS3 mRNA CTD PMID:15890375 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression EXP 2-nitrofluorene results in decreased expression of MAP2K6 mRNA CTD PMID:22484513 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression EXP 2-nitrofluorene results in decreased expression of MAT1A mRNA CTD PMID:14600272 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP 2-nitrofluorene results in increased expression of MCM6 mRNA CTD PMID:15890375 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP 2-nitrofluorene results in increased expression of MDM2 mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513, PMID:23052194 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 2-nitrofluorene results in increased expression of MGMT mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513, PMID:23052194 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP 2-nitrofluorene results in decreased expression of MT1A mRNA CTD PMID:14600272, PMID:15890375 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A decreases expression EXP 2-nitrofluorene results in decreased expression of MT2 mRNA; 2-nitrofluorene results in decreased expression of MT2A mRNA CTD PMID:14600272, PMID:15890375 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP 2-nitrofluorene results in increased expression of MYC mRNA CTD PMID:15890375 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Naglt1 Na+ dependent glucose transporter 1 affects expression EXP 2-nitrofluorene affects the expression of NAGLT1 mRNA CTD PMID:22484513 NCBI chr20:45,095,232...45,107,532
Ensembl chr20:45,094,791...45,107,555
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP 2-nitrofluorene results in increased expression of NAP1L1 mRNA CTD PMID:15890375 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 increases expression EXP 2-nitrofluorene results in increased expression of NHEJ1 mRNA CTD PMID:22484513 NCBI chr 9:82,230,230...82,327,923
Ensembl chr 9:82,230,232...82,327,534
JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP 2-nitrofluorene results in increased expression of NPM1 mRNA CTD PMID:15890375 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP 2-nitrofluorene results in increased expression of NQO1 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP 2-nitrofluorene results in increased expression of NRG1 mRNA CTD PMID:14600272, PMID:15890375, PMID:22484513, PMID:23052194 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 2-nitrofluorene results in decreased expression of NUPR1 mRNA CTD PMID:15890375, PMID:23052194 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Oat ornithine aminotransferase decreases expression EXP 2-nitrofluorene results in decreased expression of OAT mRNA CTD PMID:14600272, PMID:22484513 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Obp3 alpha-2u globulin PGCL4 decreases expression EXP 2-nitrofluorene results in decreased expression of OBP3 mRNA CTD PMID:15890375 NCBI chr 5:77,313,357...77,316,875 JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP 2-nitrofluorene results in increased expression of ODC1 mRNA CTD PMID:15890375 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 2-nitrofluorene results in increased expression of PCNA mRNA CTD PMID:15890375 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO 2-nitrofluorene results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression EXP 2-nitrofluorene results in decreased expression of PHGDH mRNA CTD PMID:15890375 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP 2-nitrofluorene results in increased expression of PHLDA3 mRNA CTD PMID:22484513, PMID:23052194 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Pmm1 phosphomannomutase 1 increases expression EXP 2-nitrofluorene results in increased expression of PMM1 mRNA CTD PMID:22484513 NCBI chr 7:123,183,504...123,193,874
Ensembl chr 7:123,183,506...123,193,761
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMA1 mRNA CTD PMID:15890375 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP 2-nitrofluorene results in increased expression of PSMA2 mRNA CTD PMID:15890375 NCBI chr17:53,091,937...53,102,324
Ensembl chr17:53,091,933...53,102,342
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMA4 mRNA CTD PMID:15890375 NCBI chr 8:59,532,456...59,539,916
Ensembl chr 8:59,532,389...59,539,920
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMA5 mRNA CTD PMID:15890375 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psma7 proteasome 20S subunit alpha 7 increases expression EXP 2-nitrofluorene results in increased expression of PSMA7 mRNA CTD PMID:15890375 NCBI chr 3:175,420,042...175,426,384
Ensembl chr 3:175,420,039...175,426,395
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMB1 mRNA CTD PMID:15890375 NCBI chr 1:57,470,878...57,491,359
Ensembl chr 1:57,470,632...57,489,727
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression EXP 2-nitrofluorene results in increased expression of PSMB3 mRNA CTD PMID:15890375 NCBI chr10:85,646,646...85,653,729
Ensembl chr10:85,646,633...85,653,729
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMB4 mRNA CTD PMID:15890375 NCBI chr 2:196,043,546...196,046,320
Ensembl chr 2:196,043,618...196,046,311
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMB5 mRNA CTD PMID:15890375 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP 2-nitrofluorene results in increased expression of PSMB8 mRNA CTD PMID:14600272 NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP 2-nitrofluorene results in increased expression of PSMB9 mRNA CTD PMID:14600272 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMC1 mRNA CTD PMID:15890375 NCBI chr 6:124,123,283...124,135,644
Ensembl chr 6:124,123,228...124,135,658
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP 2-nitrofluorene results in increased expression of PSMC2 mRNA CTD PMID:15890375 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression EXP 2-nitrofluorene results in increased expression of PSMC4 mRNA CTD PMID:15890375 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 increases expression EXP 2-nitrofluorene results in increased expression of PSMC5 mRNA CTD PMID:15890375 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 increases expression EXP 2-nitrofluorene results in increased expression of PSMD1 mRNA CTD PMID:15890375 NCBI chr 9:93,080,618...93,155,033
Ensembl chr 9:93,080,615...93,155,027
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP 2-nitrofluorene results in increased expression of PTP4A1 mRNA CTD PMID:15890375 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP 2-nitrofluorene results in decreased expression of PTTG1 mRNA CTD PMID:15890375 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP 2-nitrofluorene results in decreased expression of RB1 mRNA CTD PMID:15890375 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression EXP 2-nitrofluorene results in increased expression of RHEB mRNA CTD PMID:15890375 NCBI chr 4:6,827,429...6,873,384
Ensembl chr 4:6,827,429...6,873,383
JBrowse link
G Rhob ras homolog family member B increases expression EXP 2-nitrofluorene results in increased expression of RHOB mRNA CTD PMID:14600272, PMID:22484513 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rpl10 ribosomal protein L10 increases expression EXP 2-nitrofluorene results in increased expression of RPL10 mRNA CTD PMID:15890375 NCBI chr  X:156,438,251...156,440,461
Ensembl chr  X:156,438,251...156,440,461
JBrowse link
G Rpl10a ribosomal protein L10A increases expression EXP 2-nitrofluorene results in increased expression of RPL10A mRNA CTD PMID:15890375 NCBI chr20:7,908,309...7,910,867
Ensembl chr20:7,908,304...7,910,867
JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP 2-nitrofluorene results in increased expression of RPL13 mRNA CTD PMID:15890375 NCBI chr19:55,917,489...55,920,040
Ensembl chr19:55,917,736...55,919,996
JBrowse link
G Rpl15 ribosomal protein L15 increases expression EXP 2-nitrofluorene results in increased expression of RPL15 mRNA CTD PMID:15890375 NCBI chr15:8,188,717...8,192,153
Ensembl chr15:8,189,253...8,192,152
JBrowse link
G Rpl17 ribosomal protein L17 increases expression EXP 2-nitrofluorene results in increased expression of RPL17 mRNA CTD PMID:15890375 NCBI chr18:70,969,733...70,972,839
Ensembl chr18:70,970,596...70,975,494
JBrowse link
G Rpl23 ribosomal protein L23 increases expression EXP 2-nitrofluorene results in increased expression of RPL23 mRNA CTD PMID:15890375 NCBI chr10:85,721,398...85,725,359
Ensembl chr10:85,721,394...85,725,429
JBrowse link
G Rpl6 ribosomal protein L6 increases expression EXP 2-nitrofluorene results in increased expression of RPL6 mRNA CTD PMID:15890375 NCBI chr12:40,877,578...40,882,032
Ensembl chr12:40,877,613...40,881,124
JBrowse link
G Rpl7a ribosomal protein L7a increases expression EXP 2-nitrofluorene results in increased expression of RPL7A mRNA CTD PMID:15890375 NCBI chr 3:5,458,985...5,461,627
Ensembl chr 3:5,459,160...5,461,583
Ensembl chr 3:5,459,160...5,461,583
JBrowse link
G Rpl8 ribosomal protein L8 increases expression EXP 2-nitrofluorene results in increased expression of RPL8 mRNA CTD PMID:15890375 NCBI chr 7:117,967,608...117,969,886
Ensembl chr 7:118,507,224...118,509,256
JBrowse link
G Rps15a ribosomal protein S15a increases expression EXP 2-nitrofluorene results in increased expression of RPS15A mRNA CTD PMID:15890375 NCBI chr 1:187,759,865...187,766,734
Ensembl chr 1:187,759,480...187,766,709
JBrowse link
G Rps19 ribosomal protein S19 increases expression EXP 2-nitrofluorene results in increased expression of RPS19 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr 1:81,750,873...81,756,629
Ensembl chr 1:81,750,928...81,756,627
JBrowse link
G Rps24 ribosomal protein S24 increases expression EXP 2-nitrofluorene results in increased expression of RPS24 mRNA CTD PMID:15890375 NCBI chr16:757,390...762,091
Ensembl chr16:757,403...762,075
JBrowse link
G Rps27l ribosomal protein S27-like increases expression EXP 2-nitrofluorene results in increased expression of RPS27L mRNA CTD PMID:15890375 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G Rps3 ribosomal protein S3 increases expression EXP 2-nitrofluorene results in increased expression of RPS3 mRNA CTD PMID:15890375 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Rps4x ribosomal protein S4, X-linked increases expression EXP 2-nitrofluorene results in increased expression of RPS4X mRNA CTD PMID:15890375 NCBI chr  X:72,074,108...72,078,551
Ensembl chr  X:72,074,108...72,078,551
Ensembl chr 4:72,074,108...72,078,551
JBrowse link
G Rps7 ribosomal protein S7 increases expression EXP 2-nitrofluorene results in increased expression of RPS7 mRNA CTD PMID:15890375 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G Rpsa ribosomal protein SA increases expression EXP 2-nitrofluorene results in increased expression of RPSA mRNA CTD PMID:15890375 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression EXP 2-nitrofluorene results in decreased expression of RSAD2 mRNA CTD PMID:22484513 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression EXP 2-nitrofluorene results in increased expression of RT1-BB mRNA CTD PMID:14600272 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G RT1-Da RT1 class II, locus Da increases expression EXP 2-nitrofluorene results in increased expression of RT1-DA mRNA CTD PMID:14600272 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP 2-nitrofluorene results in increased expression of RT1-EC2 mRNA CTD PMID:14600272
G Sds serine dehydratase decreases expression EXP 2-nitrofluorene results in decreased expression of SDS mRNA CTD PMID:14600272 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Selenow selenoprotein W increases expression EXP 2-nitrofluorene results in increased expression of SELENOW mRNA CTD PMID:15890375 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 2-nitrofluorene results in increased expression of SERPINA7 mRNA CTD PMID:14600272 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression EXP 2-nitrofluorene results in increased expression of SPTAN1 mRNA CTD PMID:14600272 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression EXP 2-nitrofluorene results in increased expression of STAT1 mRNA CTD PMID:14600272 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stmn1 stathmin 1 increases expression EXP 2-nitrofluorene results in increased expression of STMN1 mRNA CTD PMID:15890375 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP 2-nitrofluorene results in increased expression of TAP1 mRNA CTD PMID:14600272 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tat tyrosine aminotransferase increases expression EXP 2-nitrofluorene results in increased expression of TAT mRNA CTD PMID:15890375 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B increases expression EXP 2-nitrofluorene results in increased expression of TIMM10B mRNA CTD PMID:15890375 NCBI chr 1:170,471,265...170,474,111
Ensembl chr 1:170,471,238...170,474,113
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 2-nitrofluorene results in increased expression of TIMP1 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tmsb10 thymosin, beta 10 increases expression EXP 2-nitrofluorene results in increased expression of TMSB10 mRNA CTD PMID:14600272 NCBI chr 4:100,882,216...100,883,303
Ensembl chr 4:100,882,216...100,883,275
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression
increases expression
ISO 2-nitrofluorene results in decreased expression of TNFAIP3 mRNA
2-nitrofluorene results in increased expression of TNFAIP3 mRNA
CTD PMID:21873647 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP 2-nitrofluorene results in increased expression of TOP2A mRNA CTD PMID:15890375 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression
ISO 2-nitrofluorene results in decreased expression of TPD52 mRNA
2-nitrofluorene results in increased expression of TPD52 mRNA
CTD PMID:21873647 NCBI chr 2:94,959,732...95,041,277
Ensembl chr 2:95,008,311...95,040,514
JBrowse link
G Trappc10 trafficking protein particle complex 10 increases expression EXP 2-nitrofluorene results in increased expression of TRAPPC10 mRNA CTD PMID:22484513 NCBI chr20:11,168,298...11,228,634
Ensembl chr20:11,168,298...11,228,625
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 2-nitrofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15890375 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Tuba1c tubulin, alpha 1C increases expression EXP 2-nitrofluorene results in increased expression of TUBA1C mRNA CTD PMID:15890375 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP 2-nitrofluorene results in increased expression of TUBB5 mRNA CTD PMID:15890375 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Tyms thymidylate synthetase increases expression EXP 2-nitrofluorene results in increased expression of TYMS mRNA CTD PMID:14600272, PMID:15890375, PMID:23052194 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C increases expression EXP 2-nitrofluorene results in increased expression of UGT1A7 mRNA CTD PMID:14600272 NCBI chr 9:95,233,957...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP 2-nitrofluorene results in increased expression of UGT2B17 mRNA CTD PMID:23052194 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP 2-nitrofluorene results in increased expression of VEGFA mRNA CTD PMID:15890375 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin increases expression EXP 2-nitrofluorene results in increased expression of VIM mRNA CTD PMID:14600272 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xdh xanthine dehydrogenase decreases expression
increases reduction
EXP
ISO
2-nitrofluorene results in decreased expression of XDH mRNA
XDH protein results in increased reduction of 2-nitrofluorene
CTD PMID:15890375, PMID:15932950 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression EXP 2-nitrofluorene results in increased expression of ZMAT3 mRNA CTD PMID:14600272, PMID:15890375 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link
4-acetylaminofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP 4-acetylaminofluorene results in increased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP 4-acetylaminofluorene results in increased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP 4-acetylaminofluorene results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression EXP 4-acetylaminofluorene results in decreased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 4-acetylaminofluorene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 4-acetylaminofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP 4-acetylaminofluorene results in increased expression of ALDH1A4 mRNA CTD PMID:17070881 NCBI chr 1:240,584,233...240,601,843
Ensembl chr 1:240,562,423...240,601,744
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 4-acetylaminofluorene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 4-acetylaminofluorene results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C7 complement C7 decreases expression EXP 4-acetylaminofluorene results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:54,707,621...54,781,624
Ensembl chr 2:54,709,138...54,777,729
JBrowse link
G Cblc Cbl proto-oncogene C increases expression EXP 4-acetylaminofluorene results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:80,699,321...80,716,146
Ensembl chr 1:80,699,323...80,716,146
JBrowse link
G Ccng1 cyclin G1 increases expression EXP 4-acetylaminofluorene results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd276 Cd276 molecule increases expression EXP 4-acetylaminofluorene results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP 4-acetylaminofluorene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 4-acetylaminofluorene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP 4-acetylaminofluorene results in decreased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP 4-acetylaminofluorene results in decreased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 4-acetylaminofluorene results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:14,559,806...14,574,345
Ensembl chr 7:14,529,482...14,574,361
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression EXP 4-acetylaminofluorene results in decreased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 4-acetylaminofluorene results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Fas Fas cell surface death receptor increases expression
decreases expression
EXP 4-acetylaminofluorene results in increased expression of FAS mRNA
4-acetylaminofluorene results in decreased expression of FAS mRNA
CTD PMID:17070881 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression EXP 4-acetylaminofluorene results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:15,697,292...16,862,873 JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 4-acetylaminofluorene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 increases expression EXP 4-acetylaminofluorene results in increased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197
Ensembl chr13:2,412,363...2,431,197
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 4-acetylaminofluorene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 4-acetylaminofluorene results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP 4-acetylaminofluorene results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Olr37 olfactory receptor 37 decreases expression EXP 4-acetylaminofluorene results in decreased expression of OLR37 mRNA CTD PMID:17070881 NCBI chr 1:164,755,094...164,756,059 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP 4-acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 4-acetylaminofluorene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:51,465,148...51,485,562
Ensembl chr15:51,465,148...51,485,692
JBrowse link
G Serpina7 serpin family A member 7 decreases expression EXP 4-acetylaminofluorene results in decreased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP 4-acetylaminofluorene results in increased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP 4-acetylaminofluorene results in increased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression EXP 4-acetylaminofluorene results in increased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Sulf2 sulfatase 2 decreases expression EXP 4-acetylaminofluorene results in decreased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP 4-acetylaminofluorene results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP 4-acetylaminofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15089088 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression EXP 4-acetylaminofluorene results in decreased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link
9,9-bis(4-hydroxyphenyl)fluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased activity of NCOA2 protein]; 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:28248286 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:28248286 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased activity of NCOA2 protein] CTD PMID:28248286 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
9-phenanthrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions EXP 9-phenanthrol inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G C3 complement C3 increases expression ISO 9-phenanthrol results in increased expression of C3 mRNA CTD PMID:22989670 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases abundance
multiple interactions
ISO CYP1A1 protein results in increased abundance of 9-phenanthrol
[CYP1A1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol
CTD PMID:27137136 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases abundance
ISO [CYP1A2 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol
CYP1A2 protein results in increased abundance of 9-phenanthrol
CTD PMID:27137136 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases abundance
multiple interactions
ISO CYP1B1 protein results in increased abundance of 9-phenanthrol
[CYP1B1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol
CTD PMID:27137136 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Esr2 estrogen receptor 2 affects binding
multiple interactions
ISO ESR2 protein binds to 9-phenanthrol
9-phenanthrol inhibits the reaction [ESR2 protein binds to Estradiol]
CTD PMID:22989670 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO 9-phenanthrol results in decreased expression of JAG1 mRNA CTD PMID:22989670 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO 9-phenanthrol results in increased expression of NRIP1 mRNA CTD PMID:22989670 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions ISO 9-phenanthrol inhibits the reaction [Arsenic Trioxide results in increased expression of TRPM4 protein] CTD PMID:31054354 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
anthracene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp2 acid phosphatase 2, lysosomal multiple interactions
affects expression
ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of ACP2 protein
anthracene affects the expression of ACP2 protein
CTD PMID:28803881 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
increases activity
affects localization
ISO
EXP
2-oxohexyl isothiocyanate inhibits the reaction [anthracene affects the localization of AHR protein]; [acenaphthene co-treated with anthracene co-treated with 1,12-benzoperylene co-treated with 1,2,5,6-dibenzanthracene co-treated with fluorene co-treated with naphthalene co-treated with phenanthrene] results in increased activity of AHR protein; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein]; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ESR1 protein]; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein]; alyssin inhibits the reaction [anthracene affects the localization of AHR protein]; sulforafan affects the reaction [anthracene affects the localization of AHR protein]
anthracene binds to AHR protein
anthracene results in increased activity of AHR protein
CTD PMID:3024361, PMID:17665671, PMID:19362136, PMID:28710019, PMID:30980910 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHRR protein; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AHR protein]; AHRR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of CYP1A1 protein] CTD PMID:28710019, PMID:30980910 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Ar androgen receptor multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein; AHR protein affects the reaction [[naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of AR protein]; anthracene inhibits the reaction [Androgens results in increased activity of AR protein]; anthracene inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785, PMID:28377212, PMID:30980910 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] affects the expression of ARNT protein; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in decreased expression of ARNT mRNA; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of ARNT mRNA CTD PMID:28710019 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
ISO [naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of BAX protein
anthracene affects the expression of BAX protein
CTD PMID:28803881 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO anthracene results in increased expression of CASP3 protein
[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CASP3 protein
CTD PMID:28803881 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccna2 cyclin A2 decreases expression
multiple interactions
ISO anthracene results in decreased expression of CCNA2 protein
[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in decreased expression of CCNA2 protein
CTD PMID:28803881 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO anthracene results in increased expression of CCND1 protein
[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CCND1 protein
CTD PMID:28803881 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression
multiple interactions
ISO anthracene results in increased expression of CDK2 protein
[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in increased expression of CDK2 protein
CTD PMID:28803881 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] affects the expression of COMT mRNA; [naphthalene co-treated with phenanthrene co-treated with anthracene co-treated with fluoranthene co-treated with pyrene] results in increased expression of and affects the activity of COMT protein CTD PMID:28710019 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO anthracene results in increased expression of CYP19A1 protein
[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of CYP19A1 protein
CTD