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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3'-deoxyribonucleoside
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Accession:CHEBI:36987 term browser browse the term
Synonyms:related_synonym: 3'-deoxyribonucleosides

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3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme affects activity EXP Puromycin Aminonucleoside affects the activity of ACE protein CTD PMID:1318808 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases activity EXP Puromycin Aminonucleoside results in decreased activity of ACMSD protein CTD PMID:16711654 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734 		JBrowse link
G Actb actin, beta decreases expression EXP Puromycin Aminonucleoside results in decreased expression of ACTB protein CTD PMID:19264907 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841 		JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of ACTG1 protein CTD PMID:19264907 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954 		JBrowse link
G Actr2 actin related protein 2 increases expression EXP Puromycin Aminonucleoside results in increased expression of ACTR2 mRNA; Puromycin Aminonucleoside results in increased expression of ACTR2 protein CTD PMID:19617259 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649 		JBrowse link
G Actr3 actin related protein 3 increases expression EXP Puromycin Aminonucleoside results in increased expression of ACTR3 protein CTD PMID:19264907 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658 		JBrowse link
G Agt angiotensinogen affects expression
decreases expression
increases expression
multiple interactions		 EXP Puromycin Aminonucleoside affects the expression of AGT protein
Puromycin Aminonucleoside results in decreased expression of AGT protein
Puromycin Aminonucleoside results in increased expression of AGT mRNA
[Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGT mRNA		 CTD PMID:2236972 PMID:8446257 PMID:12495295 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions
increases expression		 EXP [Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGTR2 mRNA
Puromycin Aminonucleoside results in increased expression of AGTR2 mRNA		 CTD PMID:12495295 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 increases expression EXP Puromycin Aminonucleoside results in increased expression of AGXT2 protein CTD PMID:19264907 NCBI chr 2:60,337,667...60,379,144
Ensembl chr 2:60,337,667...60,379,420 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
affects localization		 ISO Dexamethasone inhibits the reaction [Puromycin Aminonucleoside affects the localization of AIFM1 protein] CTD PMID:15987750 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087 		JBrowse link
G Alb albumin affects transport
increases secretion
increases expression
affects localization
decreases expression		 ISO
EXP		 Puromycin Aminonucleoside affects the transport of ALB protein
Puromycin Aminonucleoside results in increased secretion of ALB protein
Puromycin Aminonucleoside results in increased expression of ALB mRNA; Puromycin Aminonucleoside results in increased expression of ALB protein
Puromycin Aminonucleoside affects the localization of ALB protein
Puromycin Aminonucleoside results in decreased expression of ALB protein		 CTD PMID:1453496 PMID:3301049 PMID:8413769 PMID:15798086 PMID:19264907 PMID:20438795 PMID:20540862 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 increases expression EXP Puromycin Aminonucleoside results in increased expression of ALDH1A2 mRNA CTD PMID:12660332 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489 		JBrowse link
G Angpt1 angiopoietin 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of ANGPT1 mRNA CTD PMID:17667850 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression		 ISO 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of APEX1 protein] CTD PMID:17035936 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082 		JBrowse link
G Apoa1 apolipoprotein A1 decreases response to substance
increases expression		 ISO
EXP		 APOA1 protein results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased expression of APOA1 mRNA; Puromycin Aminonucleoside results in increased expression of APOA1 protein		 CTD PMID:7066357 PMID:7442475 PMID:7595070 PMID:8412754 PMID:8413767 PMID:8506949 PMID:9059516 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apoa2 apolipoprotein A2 increases expression EXP Puromycin Aminonucleoside results in increased expression of APOA2 protein CTD PMID:7442475 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802 		JBrowse link
G Apoa4 apolipoprotein A4 decreases expression
increases expression		 EXP Puromycin Aminonucleoside results in decreased expression of APOA4 protein
Puromycin Aminonucleoside results in increased expression of APOA4 mRNA; Puromycin Aminonucleoside results in increased expression of APOA4 protein		 CTD PMID:7442475 PMID:8412754 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376 		JBrowse link
G Apob apolipoprotein B increases expression EXP Puromycin Aminonucleoside results in increased expression of APOB protein CTD PMID:2725289 PMID:7442475 PMID:8506949 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997 		JBrowse link
G Apoe apolipoprotein E decreases response to substance
increases expression
affects expression		 ISO
EXP		 APOE protein results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased expression of APOE protein
Puromycin Aminonucleoside affects the expression of APOE mRNA		 CTD PMID:7442475 PMID:8413767 PMID:12472773 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Aqp2 aquaporin 2 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of AQP2 protein CTD PMID:9013444 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP Puromycin Aminonucleoside results in decreased expression of AQP3 protein CTD PMID:9013444 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression EXP Puromycin Aminonucleoside results in increased expression of ARC mRNA CTD PMID:19617259 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression
increases expression		 EXP Puromycin Aminonucleoside results in decreased expression of ATP1A1 protein
Puromycin Aminonucleoside results in increased expression of ATP1A1 mRNA		 CTD PMID:11675400 PMID:15075188 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of ATP1B1 mRNA CTD PMID:11675400 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of ATP2A2 mRNA; Puromycin Aminonucleoside results in decreased expression of ATP2A2 protein CTD PMID:17457379 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326 		JBrowse link
G Avp arginine vasopressin increases expression EXP Puromycin Aminonucleoside results in increased expression of AVP protein CTD PMID:7810534 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 Puromycin Aminonucleoside results in increased expression of BAX protein
Dinoprostone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BAX protein]
Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BAX protein]		 CTD PMID:15113391 PMID:15987750 PMID:16152783 PMID:16396944 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases activity
decreases expression		 EXP Puromycin Aminonucleoside results in decreased activity of BCAT2 protein
Puromycin Aminonucleoside results in decreased expression of BCAT2 mRNA		 CTD PMID:9399633 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080 		JBrowse link
G Bche butyrylcholinesterase increases activity EXP Puromycin Aminonucleoside results in increased activity of BCHE protein CTD PMID:1462003 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 EXP [Puromycin Aminonucleoside co-treated with Melatonin] results in increased expression of BCL2 protein
Puromycin Aminonucleoside results in increased expression of BCL2 protein		 CTD PMID:14993511 PMID:15113391 PMID:16152783 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression		 ISO
EXP		 [Puromycin Aminonucleoside co-treated with pifithrin] results in increased expression of BCL2L1 protein; Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BCL2L1 protein]
Dinoprostone affects the reaction [Puromycin Aminonucleoside results in decreased expression of BCL2L1 protein]		 CTD PMID:15987750 PMID:16396944 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP Puromycin Aminonucleoside results in increased expression of BGLAP protein CTD PMID:9154658 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Puromycin Aminonucleoside results in increased expression of BIRC5 mRNA; Puromycin Aminonucleoside results in increased expression of BIRC5 protein CTD PMID:19617259 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions
decreases expression		 EXP 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BMP7 mRNA]; 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of BMP7 protein]
Puromycin Aminonucleoside results in decreased expression of BMP7 mRNA; Puromycin Aminonucleoside results in decreased expression of BMP7 protein		 CTD PMID:19594554 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 multiple interactions
increases expression		 EXP Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA]; Fosinopril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of BMPR2 mRNA] CTD PMID:17803470 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G C3 complement C3 multiple interactions
increases expression
decreases expression		 EXP cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of C3 protein]; mizoribine inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of C3 protein] CTD PMID:8919236 PMID:9250166 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G C5 complement C5 multiple interactions ISO
EXP		 CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]
cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]; Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]		 CTD PMID:9250166 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080 		JBrowse link
G C9 complement C9 multiple interactions ISO
EXP		 CR1 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]
cobra venom factor inhibits the reaction [Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]]; Puromycin Aminonucleoside results in increased expression of [C5 protein alternative form binds to C9 protein]		 CTD PMID:9250166 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 EXP Colforsin inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]; Dinoprostone inhibits the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein]; L-161982 promotes the reaction [Puromycin Aminonucleoside results in increased activity of CASP3 protein] CTD PMID:16396944 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cat catalase increases activity
decreases activity
decreases expression
affects activity
multiple interactions		 ISO
EXP		 Puromycin Aminonucleoside results in increased activity of CAT protein
Puromycin Aminonucleoside results in decreased activity of CAT protein
Puromycin Aminonucleoside results in decreased expression of CAT mRNA
Puromycin Aminonucleoside affects the activity of CAT protein
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of CAT protein; Cyclosporine inhibits the reaction [Puromycin Aminonucleoside results in decreased activity of CAT protein]; Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of CAT protein; sho-saiko-to-kyo-shokyo-ka-oren-bukuryo inhibits the reaction [Puromycin Aminonucleoside results in decreased activity of CAT protein]		 CTD PMID:1744988 PMID:1942778 PMID:6246912 PMID:8289993 PMID:9355075 PMID:10468195 PMID:15113391 PMID:15496159 PMID:20685819 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 affects expression EXP Puromycin Aminonucleoside affects the expression of CCL1 mRNA CTD PMID:10867541 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression
multiple interactions
increases expression		 EXP Puromycin Aminonucleoside affects the expression of CCL2 mRNA
fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CCL2 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CCL2 protein]
Puromycin Aminonucleoside results in increased expression of CCL2 mRNA; Puromycin Aminonucleoside results in increased expression of CCL2 protein		 CTD PMID:10867541 PMID:12813006 PMID:16452496 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 affects expression EXP Puromycin Aminonucleoside affects the expression of CCL3 mRNA CTD PMID:10867541 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 affects expression EXP Puromycin Aminonucleoside affects the expression of CCL7 mRNA CTD PMID:10867541 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Cd2ap CD2-associated protein multiple interactions
decreases expression		 EXP celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CD2AP mRNA] CTD PMID:19194550 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504 		JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression		 EXP
ISO		 Puromycin Aminonucleoside results in increased expression of and results in increased glycosylation of CD36 protein
Puromycin Aminonucleoside results in increased expression of CD36 mRNA		 CTD PMID:19264907 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP Puromycin Aminonucleoside results in increased expression of CD44 protein CTD PMID:8635280 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO
EXP		 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CDKN1A protein] CTD PMID:17035936 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CHST11 mRNA CTD PMID:15585670 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of CHSY1 mRNA CTD PMID:15585670 NCBI chr 1:127,010,587...127,071,570
Ensembl chr 1:127,010,588...127,071,570 		JBrowse link
G Cldn6 claudin 6 affects localization EXP Puromycin Aminonucleoside affects the localization of CLDN6 protein CTD PMID:18367650 NCBI chr10:12,999,256...13,002,860
Ensembl chr10:13,000,090...13,002,862 		JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CLIC5 protein CTD PMID:19264907 NCBI chr 9:19,121,676...19,372,673
Ensembl chr 9:19,121,677...19,372,673 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression		 EXP 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL1A1 mRNA] CTD PMID:9527400 PMID:16570917 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Puromycin Aminonucleoside results in increased expression of COL3A1 mRNA CTD PMID:9527400 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153 		JBrowse link
G Corin corin, serine peptidase decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CORIN mRNA; Puromycin Aminonucleoside results in decreased expression of CORIN protein CTD PMID:20613715 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CTNNB1 protein CTD PMID:12065681 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Ctsb cathepsin B decreases activity EXP Puromycin Aminonucleoside results in decreased activity of CTSB protein CTD PMID:10394110 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612 		JBrowse link
G Ctsd cathepsin D increases activity EXP Puromycin Aminonucleoside results in increased activity of CTSD protein CTD PMID:6497855 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451 		JBrowse link
G Ctsh cathepsin H decreases activity EXP Puromycin Aminonucleoside results in decreased activity of CTSH protein CTD PMID:10394110 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287 		JBrowse link
G Ctsl cathepsin L decreases response to substance
multiple interactions
decreases activity
affects expression		 ISO
EXP		 CTSL gene mutant form results in decreased susceptibility to Puromycin Aminonucleoside
Puromycin Aminonucleoside results in increased activity of and results in increased expression of CTSL protein
Puromycin Aminonucleoside results in decreased activity of CTSL protein
Puromycin Aminonucleoside affects the expression of CTSL mRNA; Puromycin Aminonucleoside affects the expression of CTSL protein		 CTD PMID:10394110 PMID:15197181 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression		 EXP [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; CGB3 protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; FSHB protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA] CTD PMID:16574160 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of CYP24A1 mRNA CTD PMID:19297354 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CYP27B1 mRNA CTD PMID:19297354 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of CYP2B1 protein CTD PMID:12806184 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783 		JBrowse link
G Ddc dopa decarboxylase decreases activity EXP Puromycin Aminonucleoside results in decreased activity of DDC protein CTD PMID:16204272 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774 		JBrowse link
G Ddn dendrin decreases expression EXP Puromycin Aminonucleoside results in decreased expression of DDN protein CTD PMID:20588063 NCBI chr 7:140,479,707...140,486,093
Ensembl chr 7:140,479,711...140,483,693 		JBrowse link
G Des desmin increases expression
multiple interactions		 EXP Puromycin Aminonucleoside results in increased expression of DES protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein]		 CTD PMID:2183627 PMID:18509322 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294 		JBrowse link
G Dnm3 dynamin 3 increases expression EXP Puromycin Aminonucleoside results in increased expression of DNM3 mRNA CTD PMID:19617259 NCBI chr13:79,906,711...80,379,967
Ensembl chr13:79,910,382...80,379,929 		JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of ECE1 mRNA; Puromycin Aminonucleoside results in increased expression of ECE1 protein CTD PMID:12972712 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of ECHS1 protein CTD PMID:19264907 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
Ensembl chr 1:212,570,195...212,579,057 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [EDN1 protein results in increased abundance of Cyclic GMP] CTD PMID:7756592 PMID:9175058 PMID:12972712 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Edn3 endothelin 3 multiple interactions EXP Puromycin Aminonucleoside promotes the reaction [EDN3 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450 		JBrowse link
G Ednra endothelin receptor type A increases expression EXP Puromycin Aminonucleoside results in increased expression of EDNRA mRNA CTD PMID:12972712 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression		 EXP Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDNRB mRNA] CTD PMID:7756592 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha decreases expression EXP Puromycin Aminonucleoside results in decreased expression of ETFA protein CTD PMID:19264907 NCBI chr 8:60,028,786...60,086,352
Ensembl chr 8:60,028,789...60,086,403 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression EXP Puromycin Aminonucleoside results in decreased expression of ETFB protein CTD PMID:19264907 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976 		JBrowse link
G Ezr ezrin decreases expression EXP Puromycin Aminonucleoside results in decreased expression of EZR protein CTD PMID:19264907 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FAS protein] CTD PMID:14993511 PMID:16152783 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Faslg Fas ligand increases expression
multiple interactions		 EXP Puromycin Aminonucleoside results in increased expression of FASL protein
Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FASLG protein]		 CTD PMID:14993511 PMID:16152783 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Fat1 FAT atypical cadherin 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of FAT1 mRNA; Puromycin Aminonucleoside results in increased expression of FAT1 protein CTD PMID:16014031 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression
affects expression		 EXP Puromycin Aminonucleoside results in increased expression of FLT1 protein
Puromycin Aminonucleoside affects the expression of FLT1 mRNA		 CTD PMID:11744811 PMID:14752241 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 EXP Puromycin Aminonucleoside results in increased expression of FN1 mRNA; Puromycin Aminonucleoside results in increased expression of FN1 protein
Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of FN1 protein]		 CTD PMID:9527400 PMID:12813006 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression		 EXP [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Estradiol]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Progesterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased abundance of Testosterone]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA]; FSHB protein inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CYP11A1 mRNA]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of FSHB protein]
Puromycin Aminonucleoside results in decreased expression of FSHB protein		 CTD PMID:12269381 PMID:16574160 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131 		JBrowse link
G Gnaq G protein subunit alpha q increases response to substance ISO GNAQ protein results in increased susceptibility to Puromycin Aminonucleoside CTD PMID:16267159 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of FSHB protein]; Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein] CTD PMID:12269381 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression		 EXP [Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of GPX1 protein
Puromycin Aminonucleoside results in increased expression of GPX1 mRNA		 CTD PMID:1942778 PMID:20685819 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gpx3 glutathione peroxidase 3 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of GPX3 mRNA CTD PMID:20685819 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation		 EXP mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein] CTD PMID:20502051 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of GSTP1 protein CTD PMID:19264907 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Guca2b guanylate cyclase activator 2B increases expression
affects expression		 EXP Puromycin Aminonucleoside results in increased expression of GUCA2B protein
Puromycin Aminonucleoside affects the expression of GUCA2B mRNA		 CTD PMID:15590761 NCBI chr 5:138,695,591...138,697,641
Ensembl chr 5:138,695,591...138,697,641 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO
EXP		 Puromycin Aminonucleoside results in decreased expression of HADH protein CTD PMID:19264907 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity EXP Puromycin Aminonucleoside results in increased activity of HMGCR protein CTD PMID:3794548 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 EXP [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in increased expression of HMOX1 protein]
Puromycin Aminonucleoside results in increased expression of HMOX1 mRNA; Puromycin Aminonucleoside results in increased expression of HMOX1 protein		 CTD PMID:12806184 PMID:20685819 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hpse heparanase increases expression EXP Puromycin Aminonucleoside results in increased expression of HPSE mRNA; Puromycin Aminonucleoside results in increased expression of HPSE protein CTD PMID:11576343 NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224 		JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HS3ST1 mRNA CTD PMID:15585670 NCBI chr14:75,880,410...75,881,346
Ensembl chr14:75,852,060...75,882,693 		JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of HS6ST1 mRNA CTD PMID:15585670 NCBI chr 9:42,620,006...42,659,184
Ensembl chr 9:42,620,006...42,659,184 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity EXP Puromycin Aminonucleoside results in decreased activity of HSD11B2 protein CTD PMID:11981059 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of HSPA5 protein CTD PMID:19264907 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects localization EXP Puromycin Aminonucleoside affects the localization of HSPA8 protein CTD PMID:1614035 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of HSPD1 protein CTD PMID:19264907 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of ICAM1 protein CTD PMID:8635280 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il1b interleukin 1 beta increases expression EXP Puromycin Aminonucleoside results in increased expression of IL1B mRNA CTD PMID:17457379 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Ilk integrin-linked kinase multiple interactions
increases activity		 EXP mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased activity of ILK protein] CTD PMID:20502051 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189 		JBrowse link
G Itga3 integrin subunit alpha 3 decreases expression
affects expression		 ISO
EXP		 Puromycin Aminonucleoside results in decreased expression of ITGA3 mRNA; Puromycin Aminonucleoside results in decreased expression of ITGA3 protein
Puromycin Aminonucleoside affects the expression of ITGA3 protein		 CTD PMID:9249603 PMID:10845833 PMID:11274237 PMID:15197181 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression
increases expression		 ISO
EXP		 Puromycin Aminonucleoside results in decreased expression of ITGB1 mRNA; Puromycin Aminonucleoside results in decreased expression of ITGB1 protein
Puromycin Aminonucleoside results in increased expression of ITGB1 protein		 CTD PMID:11274237 PMID:12065681 PMID:14559718 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535 		JBrowse link
G Kdr kinase insert domain receptor affects expression
increases expression
decreases expression		 EXP Puromycin Aminonucleoside affects the expression of KDR mRNA
Puromycin Aminonucleoside results in increased expression of KDR mRNA; Puromycin Aminonucleoside results in increased expression of KDR protein
Puromycin Aminonucleoside results in decreased expression of KDR mRNA		 CTD PMID:11744811 PMID:14752241 PMID:17667850 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kirrel1 kirre like nephrin family adhesion molecule 1 decreases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in decreased expression of KIRREL mRNA
Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of KIRREL mRNA]		 CTD PMID:18367845 NCBI chr 2:186,420,743...186,515,209
Ensembl chr 2:186,420,795...186,515,135 		JBrowse link
G Krt7 keratin 7 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of KRT7 mRNA; Puromycin Aminonucleoside results in decreased expression of KRT7 protein CTD PMID:19617259 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907 		JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB1 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079 		JBrowse link
G Lamb2 laminin subunit beta 2 multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]; FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA]; Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of LAMB2 mRNA] CTD PMID:1762292 PMID:9175058 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517 		JBrowse link
G Lcn2 lipocalin 2 increases secretion EXP Puromycin Aminonucleoside results in increased secretion of LCN2 protein CTD PMID:20438795 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546 		JBrowse link
G Lgals1 galectin 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of LGALS1 protein CTD PMID:19079321 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression		 EXP Puromycin Aminonucleoside inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein]
Puromycin Aminonucleoside results in decreased expression of LHB protein		 CTD PMID:12269381 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of MAPK1 protein CTD PMID:14559718 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of MAPK3 protein CTD PMID:14559718 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Puromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein CTD PMID:15351692 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mdk midkine multiple interactions
decreases expression		 EXP Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of MDK mRNA] CTD PMID:12660332 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Mme membrane metallo-endopeptidase decreases expression EXP Puromycin Aminonucleoside results in decreased expression of MME protein CTD PMID:19885019 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 EXP FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of MMP2 mRNA] CTD PMID:9175058 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Msn moesin increases expression EXP Puromycin Aminonucleoside results in increased expression of MSN protein CTD PMID:19264907 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression EXP Puromycin Aminonucleoside results in decreased expression of COX1 protein CTD PMID:16609681 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Myh10 myosin heavy chain 10 increases expression
affects expression		 EXP Puromycin Aminonucleoside results in increased expression of MYH10 protein
Puromycin Aminonucleoside affects the expression of MYH10 mRNA; Puromycin Aminonucleoside affects the expression of MYH10 protein		 CTD PMID:7671567 PMID:8918620 NCBI chr10:55,274,910...55,406,738
Ensembl chr10:55,275,411...55,406,732 		JBrowse link
G Myh6 myosin heavy chain 6 affects expression EXP Puromycin Aminonucleoside affects the expression of MYH6 mRNA CTD PMID:17457379 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699 		JBrowse link
G Napsa napsin A aspartic peptidase increases expression EXP Puromycin Aminonucleoside results in increased expression of NAPSA mRNA; Puromycin Aminonucleoside results in increased expression of NAPSA protein CTD PMID:12501893 NCBI chr 1:100,577,497...100,589,802
Ensembl chr 1:100,577,056...100,589,836 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 decreases expression
affects expression		 EXP Puromycin Aminonucleoside results in decreased expression of NDST1 mRNA
Puromycin Aminonucleoside affects the expression of NDST1 mRNA		 CTD PMID:14966466 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885 		JBrowse link
G Nebl nebulette decreases expression EXP Puromycin Aminonucleoside results in decreased expression of NEBL mRNA CTD PMID:19617259 NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression EXP Puromycin Aminonucleoside results in decreased expression of NEDD4L protein CTD PMID:16020936 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression		 EXP Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of NOS1 protein
Puromycin Aminonucleoside results in increased expression of NOS1 mRNA		 CTD PMID:15039144 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Puromycin Aminonucleoside results in increased expression of NOS2 mRNA CTD PMID:15039144 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions		 EXP Puromycin Aminonucleoside results in increased expression of NOS3 mRNA
Puromycin Aminonucleoside results in decreased expression of and results in decreased activity of NOS3 protein		 CTD PMID:15039144 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions
decreases phosphorylation
decreases expression
affects expression		 EXP
ISO		 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; 1,25-dihydroxyvitamin D inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; fasudil inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; Mercuric Chloride promotes the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Puromycin Aminonucleoside affects the expression of and affects the localization of NPHS1 protein; Puromycin Aminonucleoside promotes the reaction [Mercuric Chloride results in decreased expression of NPHS1 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]; Tretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]
Puromycin Aminonucleoside results in decreased phosphorylation of NPHS1 protein
Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA; Puromycin Aminonucleoside results in decreased expression of NPHS1 protein
Puromycin Aminonucleoside affects the expression of NPHS1 mRNA; Puromycin Aminonucleoside affects the expression of NPHS1 protein
Puromycin Aminonucleoside results in decreased expression of NPHS1; Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA; Puromycin Aminonucleoside results in decreased expression of NPHS1 protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA]		 CTD PMID:10792613 PMID:11012881 PMID:12012391 PMID:12065681 PMID:12386277 PMID:12660332 PMID:15363039 PMID:15385636 PMID:16452496 PMID:17890881 PMID:18256598 PMID:18367845 PMID:18509322 PMID:19079321 PMID:19194550 PMID:19443634 PMID:19594554 PMID:20071462 PMID:20540862 PMID:20588063 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin decreases expression
multiple interactions
affects expression		 ISO
EXP		 Puromycin Aminonucleoside results in decreased expression of NPHS2 protein
triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein]
Puromycin Aminonucleoside affects the expression of NPHS2 mRNA; Puromycin Aminonucleoside affects the expression of NPHS2 protein		 CTD PMID:12065681 PMID:15363039 PMID:18509322 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522 		JBrowse link
G Nppa natriuretic peptide A affects metabolic processing
increases response to substance
increases expression
multiple interactions
affects expression		 EXP Puromycin Aminonucleoside affects the metabolism of NPPA protein
Puromycin Aminonucleoside results in increased susceptibility to NPPA protein
Puromycin Aminonucleoside results in increased expression of NPPA mRNA; Puromycin Aminonucleoside results in increased expression of NPPA protein
Puromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]
Puromycin Aminonucleoside affects the expression of NPPA protein		 CTD PMID:2526952 PMID:12972712 PMID:15590761 PMID:19885019 PMID:20613715 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nppb natriuretic peptide B affects expression EXP Puromycin Aminonucleoside affects the expression of NPPB mRNA CTD PMID:17457379 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of NPR1 mRNA CTD PMID:19885019 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090 		JBrowse link
G Npr3 natriuretic peptide receptor 3 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of NPR3 mRNA CTD PMID:19885019 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926 		JBrowse link
G Nrf1 nuclear respiratory factor 1 affects expression EXP Puromycin Aminonucleoside affects the expression of NRF1 mRNA CTD PMID:16609681 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341 		JBrowse link
G Optn optineurin increases expression EXP
ISO		 Puromycin Aminonucleoside results in increased expression of OPTN protein CTD PMID:25096716 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389 		JBrowse link
G Pdpn podoplanin decreases expression ISO
EXP		 Puromycin Aminonucleoside results in decreased expression of PDPN mRNA; Puromycin Aminonucleoside results in decreased expression of PDPN protein CTD PMID:9327748 PMID:12032185 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441 		JBrowse link
G Plekhh2 pleckstrin homology, MyTH4 and FERM domain containing H2 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of PLEKHH2 protein CTD PMID:20588063 NCBI chr 6:7,784,743...7,895,986
Ensembl chr 6:7,793,735...7,893,769 		JBrowse link
G Pln phospholamban increases expression EXP Puromycin Aminonucleoside results in increased expression of PLN mRNA CTD PMID:17457379 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904 		JBrowse link
G Podxl podocalyxin-like increases expression
affects metabolic processing		 ISO
EXP		 Puromycin Aminonucleoside results in increased expression of PODXL mRNA; Puromycin Aminonucleoside results in increased expression of PODXL protein
Puromycin Aminonucleoside affects the metabolism of PODXL protein		 CTD PMID:8780404 PMID:11274237 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170 		JBrowse link
G Polb DNA polymerase beta increases expression
multiple interactions		 ISO Puromycin Aminonucleoside results in increased expression of POLB protein
1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of POLB protein]		 CTD PMID:17035936 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression		 EXP pioglitazone affects the reaction [Puromycin Aminonucleoside results in increased expression of PPARG protein] CTD PMID:16598202 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation
increases expression
multiple interactions		 ISO
EXP		 Puromycin Aminonucleoside results in increased phosphorylation of PPP1R12A protein
Puromycin Aminonucleoside results in increased expression of PPP1R12A protein modified form
Y 27632 inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of PPP1R12A protein]
fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PPP1R12A protein modified form]		 CTD PMID:16452496 PMID:18367845 NCBI chr 7:51,404,971...51,515,382
Ensembl chr 7:51,404,919...51,515,373 		JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of PRDX3 protein CTD PMID:19264907 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
affects response to substance
multiple interactions		 ISO
EXP		 Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA; Puromycin Aminonucleoside results in increased expression of PTGS2 protein
PTGS2 protein affects the susceptibility to Puromycin Aminonucleoside
celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA]		 CTD PMID:16396944 PMID:17890881 PMID:19194550 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Pth parathyroid hormone increases expression EXP Puromycin Aminonucleoside results in increased expression of PTH protein CTD PMID:1328752 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions EXP Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of PTK2 protein CTD PMID:14559718 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O affects expression EXP Puromycin Aminonucleoside affects the expression of PTPRO mRNA; Puromycin Aminonucleoside affects the expression of PTPRO protein CTD PMID:11961407 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression EXP Puromycin Aminonucleoside results in increased expression of RARA mRNA; Puromycin Aminonucleoside results in increased expression of RARA protein CTD PMID:12660332 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210 		JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor decreases expression ISO Puromycin Aminonucleoside results in decreased expression of RBBP7 protein CTD PMID:15798086 NCBI chr  X:33,648,682...33,665,821
Ensembl chr  X:33,648,682...33,665,821 		JBrowse link
G Ren renin multiple interactions
increases expression
affects expression		 EXP Puromycin Aminonucleoside affects the expression of and affects the activity of REN protein; Puromycin Aminonucleoside results in increased expression of and results in increased activity of REN protein
Puromycin Aminonucleoside results in increased expression of REN protein
Puromycin Aminonucleoside affects the expression of REN protein		 CTD PMID:2236972 PMID:2267444 PMID:8446257 PMID:9171944 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151 		JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression		 ISO
EXP		 fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of RHOA protein] CTD PMID:16452496 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha affects expression
multiple interactions
decreases expression
affects localization		 EXP Puromycin Aminonucleoside affects the expression of SCNN1A mRNA
Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1A protein
Puromycin Aminonucleoside results in decreased expression of SCNN1A mRNA
Puromycin Aminonucleoside affects the localization of SCNN1A protein		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta affects expression
increases expression
decreases expression
multiple interactions
affects localization		 EXP Puromycin Aminonucleoside affects the expression of SCNN1B mRNA
Puromycin Aminonucleoside results in increased expression of SCNN1B mRNA
Puromycin Aminonucleoside results in decreased expression of SCNN1B mRNA
Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1B protein
Puromycin Aminonucleoside affects the localization of SCNN1B protein		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions
increases expression
decreases expression		 EXP Puromycin Aminonucleoside affects the localization of and affects the expression of SCNN1G protein; Puromycin Aminonucleoside results in increased expression of and results in increased localization of SCNN1G protein
Puromycin Aminonucleoside results in increased expression of SCNN1G mRNA
Puromycin Aminonucleoside results in decreased expression of SCNN1G mRNA		 CTD PMID:12653683 PMID:15075188 PMID:16020936 PMID:16267158 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases expression		 EXP pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA] CTD PMID:16598202 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of SLC12A1 protein CTD PMID:15075188 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of SLC12A3 protein CTD PMID:15075188 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 affects expression EXP Puromycin Aminonucleoside affects the expression of SLC22A2 mRNA CTD PMID:22005293 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 increases response to substance ISO SLC29A4 results in increased susceptibility to Puromycin Aminonucleoside CTD PMID:19357181 NCBI chr12:13,914,114...13,924,511
Ensembl chr12:13,914,114...13,924,531 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression EXP Puromycin Aminonucleoside results in increased expression of SLC5A3 mRNA CTD PMID:15031335 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Slc9a3 solute carrier family 9 member A3 multiple interactions
decreases expression
affects expression		 EXP [piperine co-treated with Cimetidine co-treated with Pyruvates] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of SLC9A3 protein]
Puromycin Aminonucleoside affects the expression of SLC9A3 protein		 CTD PMID:12191963 PMID:12806184 PMID:15075188 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070 		JBrowse link
G Smad1 SMAD family member 1 increases expression EXP Puromycin Aminonucleoside results in increased expression of SMAD1 mRNA CTD PMID:17803470 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684 		JBrowse link
G Sod2 superoxide dismutase 2 affects expression
decreases expression
multiple interactions		 ISO
EXP		 Puromycin Aminonucleoside affects the expression of SOD2 protein
Puromycin Aminonucleoside results in decreased expression of SOD2 protein
[Methylprednisolone co-treated with Puromycin Aminonucleoside] results in increased activity of SOD2 protein		 CTD PMID:1942778 PMID:19264907 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sod3 superoxide dismutase 3 decreases expression EXP Puromycin Aminonucleoside results in decreased expression of SOD3 mRNA CTD PMID:20685819 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression		 EXP Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 protein]; fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 mRNA]
Puromycin Aminonucleoside results in increased expression of SPP1 mRNA; Puromycin Aminonucleoside results in increased expression of SPP1 protein		 CTD PMID:14738908 PMID:16452496 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of SRC protein CTD PMID:14559718 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression		 EXP [FSHB protein co-treated with CGB3 protein] inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of STAR mRNA] CTD PMID:16574160 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
G Synpo synaptopodin decreases expression ISO Puromycin Aminonucleoside results in decreased expression of SYNPO protein CTD PMID:15798086 NCBI chr18:55,863,081...55,921,412
Ensembl chr18:55,865,467...55,916,220 		JBrowse link
G Tagln transgelin increases expression EXP Puromycin Aminonucleoside results in increased expression of TAGLN mRNA; Puromycin Aminonucleoside results in increased expression of TAGLN protein CTD PMID:19617259 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357 		JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression EXP Puromycin Aminonucleoside results in decreased expression of TEK mRNA CTD PMID:17667850 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799 		JBrowse link
G Tf transferrin increases expression EXP Puromycin Aminonucleoside results in increased expression of TF mRNA CTD PMID:8413769 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Tfam transcription factor A, mitochondrial affects expression EXP Puromycin Aminonucleoside affects the expression of TFAM mRNA CTD PMID:16609681 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
affects expression		 EXP Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 protein]; Masoprocol inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]
Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA; Puromycin Aminonucleoside results in increased expression of TGFB1 protein
Puromycin Aminonucleoside affects the expression of TGFB1 mRNA		 CTD PMID:9527400 PMID:12397044 PMID:14738908 PMID:19194550 PMID:19594554 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression		 EXP FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA] CTD PMID:9175058 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
increases expression
affects localization		 EXP
ISO		 Cyclosporine inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TJP1 protein]
Puromycin Aminonucleoside affects the localization of TJP1 protein		 CTD PMID:15744817 PMID:15798086 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TNF mRNA] CTD PMID:8384958 PMID:17457379 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type decreases expression EXP Puromycin Aminonucleoside results in decreased expression of TNNC1 mRNA CTD PMID:19617259 NCBI chr16:7,292,207...7,295,238
Ensembl chr16:7,292,096...7,295,465 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 EXP
ISO		 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]; Melatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]
Puromycin Aminonucleoside results in increased expression of TRP53 protein
1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]; Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]		 CTD PMID:14993511 PMID:15113391 PMID:15987750 PMID:16152783 PMID:17035936 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Ttr transthyretin increases expression EXP Puromycin Aminonucleoside results in increased expression of TTR protein CTD PMID:19264907 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177 		JBrowse link
G Ucp3 uncoupling protein 3 decreases expression ISO Puromycin Aminonucleoside results in decreased expression of UCP3 protein CTD PMID:19264907 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206 		JBrowse link
G Vcan versican decreases expression ISO Puromycin Aminonucleoside results in decreased expression of VCAN mRNA; Puromycin Aminonucleoside results in decreased expression of VCAN protein CTD PMID:15585670 NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842 		JBrowse link
G Vcl vinculin affects localization
increases expression		 ISO
EXP		 Puromycin Aminonucleoside affects the localization of VCL protein
Puromycin Aminonucleoside results in increased expression of VCL mRNA; Puromycin Aminonucleoside results in increased expression of VCL protein		 CTD PMID:19617259 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702 		JBrowse link
G Vegfa vascular endothelial growth factor A affects expression
increases expression		 EXP Puromycin Aminonucleoside affects the expression of VEGFA mRNA
Puromycin Aminonucleoside results in increased expression of VEGFA protein		 CTD PMID:11744811 PMID:14752241 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vim vimentin multiple interactions
increases expression		 EXP fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of VIM mRNA] CTD PMID:16452496 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
G Wtip WT1 interacting protein affects localization ISO Puromycin Aminonucleoside affects the localization of WTIP protein CTD PMID:15798086 NCBI chr 1:89,966,496...89,999,892 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 affects expression EXP Puromycin Aminonucleoside affects the expression of XCL1 mRNA CTD PMID:10867541 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864 		JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions		 EXP Puromycin Aminonucleoside results in increased activity of XDH
[Tungsten co-treated with Puromycin Aminonucleoside] results in decreased activity of XDH protein		 CTD PMID:7583048 PMID:11041286 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494 		JBrowse link
cordycepin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [cordycepin inhibits the reaction [APP protein modified form results in increased activity of ACHE protein]]; cordycepin inhibits the reaction [APP protein modified form results in increased activity of ACHE protein] CTD PMID:30031108 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions EXP ADORA2A mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; ADORA2A mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; ADORA2A mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein] CTD PMID:24704558 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [cordycepin inhibits the reaction [APP protein modified form results in increased activity of ACHE protein]]; cordycepin inhibits the reaction [APP protein modified form results in increased activity of ACHE protein]; cordycepin inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPT protein] CTD PMID:30031108 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAD protein] CTD PMID:21310227 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects localization		 ISO Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAX protein]
cordycepin results in increased expression of BAX mRNA; cordycepin results in increased expression of BAX protein
cordycepin affects the localization of BAX protein		 CTD PMID:21310227 PMID:21933677 PMID:28987792 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO cordycepin results in decreased expression of BCL2 mRNA; cordycepin results in decreased expression of BCL2 protein
Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2 protein]		 CTD PMID:21310227 PMID:28987792 PMID:30529626 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression		 ISO Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2L1 protein] CTD PMID:21310227 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression		 ISO Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein] CTD PMID:21310227 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity		 ISO Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP3 protein]
cordycepin results in increased expression of CASP3 mRNA		 CTD PMID:21310227 PMID:21933677 PMID:28987792 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage		 EXP acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; ADORA2A mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; pifithrin inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; TP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; ZM 241385 inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein] CTD PMID:24704558 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity		 ISO Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP8 protein] CTD PMID:21310227 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity		 ISO Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP9 protein]
cordycepin results in increased expression of CASP9 mRNA		 CTD PMID:21310227 PMID:21933677 PMID:28987792 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase decreases expression ISO cordycepin results in decreased expression of CAT mRNA CTD PMID:28987792 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA] CTD PMID:23690541 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA] CTD PMID:23690541 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP cordycepin inhibits the reaction [pyridine results in increased expression of CYP3A2 mRNA] CTD PMID:11181506 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP cordycepin inhibits the reaction [pyridine results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:11181506 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation EXP cordycepin results in increased phosphorylation of EIF2A protein CTD PMID:23690541 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO cordycepin results in decreased expression of GPX1 mRNA CTD PMID:28987792 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression ISO cordycepin results in increased expression of MAP1LC3A mRNA CTD PMID:28987792 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions EXP cordycepin inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPT protein] CTD PMID:30031108 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 EXP acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; ADORA2A mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; pifithrin inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; TP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; ZM 241385 inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein] CTD PMID:24704558 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO cordycepin results in decreased expression of SOD1 mRNA CTD PMID:28987792 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions EXP cordycepin inhibits the reaction [Etoposide results in increased activity of SP1 protein]; cordycepin inhibits the reaction [Etoposide results in increased expression of SP1 mRNA] CTD PMID:23690541 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 EXP
ISO		 ADORA2A mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein]; cordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]; cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein; TP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; TP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; ZM 241385 inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein]
cordycepin results in increased expression of TP53 mRNA		 CTD PMID:23690541 PMID:24704558 PMID:28987792 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression
multiple interactions		 ISO cordycepin results in decreased expression of XIAP protein
Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of XIAP protein]		 CTD PMID:21310227 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19770
      atom 19768
        nonmetal atom 19651
          nitrogen atom 18582
            nitrogen molecular entity 18582
              nucleobase-containing molecular entity 5342
                nucleoside 5342
                  deoxyribonucleoside 2736
                    3'-deoxyribonucleoside 209
                      (2R,3S,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-oxolanol 0
                      (2S)-2-amino-N-[(2S,3S,4R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide 0
                      2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide 0
                      2-amino-N-[5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide 0
                      3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine 191
                      3'-deoxyguanosine 0
                      benzoic acid [5-(6-benzamido-9-purinyl)-3-fluoro-4-hydroxy-2-oxolanyl]methyl ester 0
                      cordycepin + 26
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            heteroorganic entity 19206
                              organochalcogen compound 18951
                                organooxygen compound 18877
                                  carbohydrates and carbohydrate derivatives 12259
                                    carbohydrate 12259
                                      carbohydrate derivative 11889
                                        glycosyl compound 10958
                                          N-glycosyl compound 5480
                                            nucleoside 5342
                                              deoxyribonucleoside 2736
                                                3'-deoxyribonucleoside 209
                                                  (2R,3S,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-oxolanol 0
                                                  (2S)-2-amino-N-[(2S,3S,4R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide 0
                                                  2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide 0
                                                  2-amino-N-[5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide 0
                                                  3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine 191
                                                  3'-deoxyguanosine 0
                                                  benzoic acid [5-(6-benzamido-9-purinyl)-3-fluoro-4-hydroxy-2-oxolanyl]methyl ester 0
                                                  cordycepin + 26
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