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G |
SLC22A5 |
solute carrier family 22 member 5 |
increases uptake |
EXP |
SLC22A5 protein results in increased uptake of Carnitine |
CTD |
PMID:16826461 |
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NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219
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G |
BCHE |
butyrylcholinesterase |
increases hydrolysis |
EXP |
BCHE protein results in increased hydrolysis of Butyrylthiocholine |
CTD |
PMID:22407886 |
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NCBI chr13:104,946,732...105,007,568
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G |
CD14 |
CD14 molecule |
affects expression |
EXP |
cadmium nitrate affects the expression of CD14 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
affects expression affects secretion |
EXP |
cadmium nitrate affects the expression of CXCL8 mRNA cadmium nitrate affects the secretion of CXCL8 protein |
CTD |
PMID:29421334 |
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NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
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G |
DEFB1 |
defensin beta 1 |
increases expression |
EXP |
cadmium nitrate results in increased expression of DEFB1 mRNA |
CTD |
PMID:29421334 |
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G |
IFNB1 |
interferon beta 1 |
increases expression |
EXP |
cadmium nitrate results in increased expression of IFNB1 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495
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G |
IL18 |
interleukin 18 |
increases expression |
EXP |
cadmium nitrate results in increased expression of IL18 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
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G |
IL6 |
interleukin 6 |
increases expression |
EXP |
cadmium nitrate results in increased expression of IL6 mRNA |
CTD |
PMID:29421334 |
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NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
LOC110258578 |
interleukin-1 beta-like |
increases expression |
EXP |
cadmium nitrate results in increased expression of IL1B mRNA |
CTD |
PMID:29421334 |
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G |
MAPK14 |
mitogen-activated protein kinase 14 |
affects expression |
EXP |
cadmium nitrate affects the expression of MAPK14 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,877...31,862,031
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
increases expression |
EXP |
cadmium nitrate results in increased expression of MAPK8 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874
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G |
MYD88 |
MYD88 innate immune signal transduction adaptor |
affects expression |
EXP |
cadmium nitrate affects the expression of MYD88 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
affects expression |
EXP |
cadmium nitrate affects the expression of NFKB1 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
increases expression |
EXP |
cadmium nitrate results in increased expression of RELA mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
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G |
SOCS1 |
suppressor of cytokine signaling 1 |
decreases expression |
EXP |
cadmium nitrate results in decreased expression of SOCS1 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967
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G |
STAT3 |
signal transducer and activator of transcription 3 |
decreases expression |
EXP |
cadmium nitrate results in decreased expression of STAT3 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
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G |
TLR4 |
toll like receptor 4 |
affects expression |
EXP |
cadmium nitrate affects the expression of TLR4 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
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G |
TLR5 |
toll like receptor 5 |
increases expression |
EXP |
cadmium nitrate results in increased expression of TLR5 mRNA |
CTD |
PMID:29421334 |
|
NCBI chr10:19,387,666...19,410,024
Ensembl chr10:19,387,666...19,410,024
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G |
TNF |
tumor necrosis factor |
increases expression |
EXP |
cadmium nitrate results in increased expression of TNF mRNA |
CTD |
PMID:29421334 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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G |
ENPEP |
glutamyl aminopeptidase |
multiple interactions |
EXP |
Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] |
CTD |
PMID:8141778 |
|
NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510
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G |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
EXP |
[Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein |
CTD |
PMID:26582256 |
|
NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
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G |
SLC22A5 |
solute carrier family 22 member 5 |
decreases activity |
EXP |
pivaloylcarnitine results in decreased activity of SLC22A5 protein |
CTD |
PMID:16826461 |
|
NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219
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G |
CAT |
catalase |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein |
CTD |
PMID:29129240 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
DNMT1 |
DNA methyltransferase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GYS1 |
glycogen synthase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter |
CTD |
PMID:29065941 |
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NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
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G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter |
CTD |
PMID:29065941 |
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NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
MTHFR |
methylenetetrahydrofolate reductase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
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G |
SI |
sucrase-isomaltase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA |
CTD |
PMID:28445388 |
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NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
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G |
SLC15A1 |
solute carrier family 15 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
AOC1 |
amine oxidase copper containing 1 |
affects binding |
EXP |
cobaltous chloride binds to AOC1 protein |
CTD |
PMID:16842785 |
|
NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
cobaltous chloride results in increased expression of HSP90B1 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
cobaltous chloride results in increased expression of HSPA5 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
ADCYAP1 |
adenylate cyclase activating polypeptide 1 |
decreases activity |
EXP |
Colforsin results in decreased activity of ADCYAP1 protein alternative form |
CTD |
PMID:16847435 |
|
NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294
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G |
ATP7B |
ATPase copper transporting beta |
multiple interactions |
EXP |
Colforsin inhibits the reaction [Copper binds to ATP7B protein] |
CTD |
PMID:21084060 |
|
NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
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G |
CFTR |
CF transmembrane conductance regulator |
increases activity |
EXP |
Colforsin results in increased activity of CFTR protein |
CTD |
PMID:15246976 |
|
NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950
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G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions increases phosphorylation |
EXP |
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:17680988 |
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NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728
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G |
AOC1 |
amine oxidase copper containing 1 |
increases activity |
EXP |
cupric chloride results in increased activity of AOC1 protein |
CTD |
PMID:16842785 |
|
NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
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G |
ATOX1 |
antioxidant 1 copper chaperone |
increases expression |
EXP |
Copper Sulfate results in increased expression of ATOX1 mRNA |
CTD |
PMID:22585802 |
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NCBI chr16:71,299,321...71,314,598
Ensembl chr16:71,299,321...71,314,597
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G |
CCNB1 |
cyclin B1 |
increases secretion |
EXP |
Copper Sulfate results in increased secretion of CCNB1 protein |
CTD |
PMID:24521407 |
|
NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
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G |
COX17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
EXP |
Copper Sulfate results in decreased expression of COX17 mRNA |
CTD |
PMID:22585802 |
|
NCBI chr13:140,584,286...140,594,636
Ensembl chr13:140,584,363...140,587,621
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G |
GHRH |
growth hormone releasing hormone |
increases expression |
EXP |
Copper Sulfate results in increased expression of GHRH mRNA |
CTD |
PMID:21110139 |
|
NCBI chr17:40,386,725...40,398,312
Ensembl chr17:40,387,344...40,397,857
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
Copper Sulfate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Copper Sulfate results in increased expression of HSPA5 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
IGF1 |
insulin like growth factor 1 |
increases secretion |
EXP |
Copper Sulfate results in increased secretion of IGF1 protein |
CTD |
PMID:24521407 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
SST |
somatostatin |
decreases expression |
EXP |
Copper Sulfate results in decreased expression of SST mRNA; Copper Sulfate results in decreased expression of SST protein |
CTD |
PMID:21110139 |
|
NCBI chr13:125,337,560...125,338,742
Ensembl chr13:125,337,418...125,338,850
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G |
BAK1 |
BCL2 antagonist/killer 1 |
multiple interactions |
EXP |
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAK1 protein] |
CTD |
PMID:26607349 |
|
NCBI chr 7:29,808,849...29,815,345
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions affects expression |
EXP |
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAX protein] Sodium Selenite affects the expression of BAX mRNA |
CTD |
PMID:17342738 PMID:26607349 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BCL2L1 |
BCL2 like 1 |
affects expression |
EXP |
Sodium Selenite affects the expression of BCL2L1 mRNA |
CTD |
PMID:17342738 |
|
NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
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G |
CASP3 |
caspase 3 |
multiple interactions decreases expression |
EXP |
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP3 protein] Sodium Selenite results in decreased expression of CASP3 protein |
CTD |
PMID:15191356 PMID:17342738 PMID:26607349 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP9 |
caspase 9 |
multiple interactions |
EXP |
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP9 protein] |
CTD |
PMID:26607349 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
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G |
GPX4 |
glutathione peroxidase 4 |
increases activity |
EXP |
Sodium Selenite results in increased activity of GPX4 protein |
CTD |
PMID:10998458 |
|
NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
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G |
KDSR |
3-ketodihydrosphingosine reductase |
multiple interactions |
EXP |
Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein] |
CTD |
PMID:26607349 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases expression |
EXP |
Sodium Selenite results in increased expression of MAPK1 protein |
CTD |
PMID:17342738 |
|
NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases expression |
EXP |
Sodium Selenite results in increased expression of MAPK3 protein |
CTD |
PMID:17342738 |
|
NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
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G |
MIR125A |
microRNA mir-125a |
multiple interactions |
EXP |
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]; Sodium Selenite inhibits the reaction [Cadmium results in decreased expression of MIR125A mRNA]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP9 protein] |
CTD |
PMID:26607349 |
|
NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
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G |
POMC |
proopiomelanocortin |
multiple interactions |
EXP |
Ditiocarb promotes the reaction [Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]]; Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone] |
CTD |
PMID:21466817 |
|
NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
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G |
ABCB1 |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
affects expression |
EXP |
flunixin meglumine affects the expression of ABCB1 mRNA |
CTD |
PMID:26366864 |
|
NCBI chr 9:93,049,955...93,146,469
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
affects expression |
EXP |
flunixin meglumine affects the expression of CYP1A2 mRNA |
CTD |
PMID:26366864 |
|
NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
affects expression |
EXP |
flunixin meglumine affects the expression of CYP2E1 mRNA |
CTD |
PMID:26366864 |
|
NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817
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G |
CYP3A22 |
cytochrome P450 family 3 subfamily A member 22 |
affects expression |
EXP |
flunixin meglumine affects the expression of CYP3A22 mRNA |
CTD |
PMID:26366864 |
|
NCBI chr 3:6,617,256...6,665,179
Ensembl chr 3:6,615,343...6,822,817
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G |
CYP3A29 |
cytochrome P450 family 3 subfamily A member 29 |
affects expression |
EXP |
flunixin meglumine affects the expression of CYP3A29 mRNA |
CTD |
PMID:26366864 |
|
NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
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G |
SULT1A3 |
sulfotransferase family 1A member 3 |
affects expression |
EXP |
flunixin meglumine affects the expression of SULT1A1 mRNA |
CTD |
PMID:26366864 |
|
NCBI chr 3:18,351,205...18,354,653
Ensembl chr 3:18,351,194...18,354,649
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G |
CAT |
catalase |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein |
CTD |
PMID:29129240 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
DNMT1 |
DNA methyltransferase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GYS1 |
glycogen synthase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter |
CTD |
PMID:29065941 |
|
NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
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G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter |
CTD |
PMID:29065941 |
|
NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
MTHFR |
methylenetetrahydrofolate reductase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
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G |
SI |
sucrase-isomaltase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA |
CTD |
PMID:28445388 |
|
NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
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G |
SLC15A1 |
solute carrier family 15 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
AKT1 |
AKT serine/threonine kinase 1 |
increases expression |
EXP |
lead acetate results in increased expression of AKT1 mRNA |
CTD |
PMID:29273543 |
|
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G |
AMH |
anti-Mullerian hormone |
decreases expression multiple interactions |
EXP |
lead acetate results in decreased expression of AMH mRNA lead acetate results in decreased expression of and results in decreased secretion of AMH protein |
CTD |
PMID:29273543 |
|
NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,414,427...76,418,312
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol] |
CTD |
PMID:29273543 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
FSHR |
follicle stimulating hormone receptor |
decreases expression |
EXP |
lead acetate results in decreased expression of FSHR mRNA |
CTD |
PMID:29273543 |
|
NCBI chr 3:91,607,236...91,775,255
Ensembl chr 3:91,607,305...91,774,683
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
lead acetate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
lead acetate results in increased expression of HSPA5 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
INHA |
inhibin subunit alpha |
multiple interactions |
EXP |
lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein] |
CTD |
PMID:29273543 |
|
NCBI chr15:121,581,847...121,586,020
Ensembl chr15:121,580,803...121,586,006
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G |
INHBB |
inhibin subunit beta B |
decreases expression multiple interactions |
EXP |
lead acetate results in decreased expression of INHBB mRNA lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein]; lead acetate results in decreased expression of and results in decreased secretion of INHBB protein |
CTD |
PMID:29273543 |
|
NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405
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G |
MTOR |
mechanistic target of rapamycin kinase |
increases expression |
EXP |
lead acetate results in increased expression of MTOR mRNA |
CTD |
PMID:29273543 |
|
NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
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G |
CASP3 |
caspase 3 |
increases expression |
EXP |
Lead results in increased expression of CASP3 |
CTD |
PMID:20390873 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CCNB1 |
cyclin B1 |
increases expression |
EXP |
Lead results in increased expression of CCNB1 |
CTD |
PMID:20390873 |
|
NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
[FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone |
CTD |
PMID:20390873 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
IGF1 |
insulin like growth factor 1 |
increases secretion |
EXP |
Lead results in increased secretion of IGF1 protein |
CTD |
PMID:20390873 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
Lead binds to and results in decreased folding of LDHA protein |
CTD |
PMID:18501191 |
|
NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
CHRM2 |
cholinergic receptor muscarinic 2 |
multiple interactions |
EXP |
methoctramine inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM2 protein] |
CTD |
PMID:8744975 |
|
NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186
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G |
ACACA |
acetyl-CoA carboxylase alpha |
increases expression multiple interactions |
EXP |
Sodium Glutamate results in increased expression of ACACA mRNA Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of ACACA mRNA] |
CTD |
PMID:31360149 |
|
NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712
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G |
ACOX1 |
acyl-CoA oxidase 1 |
increases expression |
EXP |
Sodium Glutamate results in increased expression of ACOX1 mRNA |
CTD |
PMID:31360149 |
|
NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546
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G |
FASN |
fatty acid synthase |
multiple interactions increases expression |
EXP |
Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA] |
CTD |
PMID:31360149 |
|
NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561
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G |
FFAR2 |
free fatty acid receptor 2 |
multiple interactions affects expression |
EXP |
Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR2 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR2 mRNA] |
CTD |
PMID:31360149 |
|
NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,901,159...44,904,459
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G |
FFAR4 |
free fatty acid receptor 4 |
affects expression multiple interactions |
EXP |
Sodium Glutamate affects the expression of FFAR4 mRNA Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR4 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR4 mRNA] |
CTD |
PMID:31360149 |
|
Ensembl chr14:105,011,942...105,037,498
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G |
GPR119 |
G protein-coupled receptor 119 |
affects expression multiple interactions |
EXP |
Sodium Glutamate affects the expression of GPR119 mRNA Dietary Fats affects the reaction [Sodium Glutamate affects the expression of GPR119 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of GPR119 mRNA] |
CTD |
PMID:31360149 |
|
NCBI chr X:106,872,225...106,873,299
Ensembl chr X:106,872,225...106,873,299
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G |
LOC110255234 |
liver carboxylesterase-like |
multiple interactions |
EXP |
Sodium Glutamate inhibits the reaction [Dietary Fats results in decreased expression of CES1 mRNA] |
CTD |
PMID:31360149 |
|
|
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G |
PNPLA2 |
patatin like phospholipase domain containing 2 |
increases expression |
EXP |
Sodium Glutamate results in increased expression of PNPLA2 mRNA |
CTD |
PMID:31360149 |
|
NCBI chr 2:513,065...517,962
Ensembl chr 2:513,077...518,182
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G |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions increases expression |
EXP |
Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of SREBF1 mRNA] |
CTD |
PMID:31360149 |
|
NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267
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G |
SLC22A5 |
solute carrier family 22 member 5 |
increases uptake |
EXP |
SLC22A5 protein results in increased uptake of Acetylcarnitine |
CTD |
PMID:16826461 |
|
NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219
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G |
ABCB4 |
ATP binding cassette subfamily B member 4 |
increases export multiple interactions |
EXP |
ABCB4 protein results in increased export of Phosphatidylcholines Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] |
CTD |
PMID:21056966 |
|
NCBI chr 9:93,171,371...93,262,124
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G |
PDIA3 |
protein disulfide isomerase family A member 3 |
increases hydrolysis |
EXP |
PDIA3 protein results in increased hydrolysis of Phosphatidylcholines |
CTD |
PMID:16798117 |
|
NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
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G |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
decreases activity |
EXP |
potassium chromate(VI) results in decreased activity of GAPDH protein |
CTD |
PMID:26582256 |
|
NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
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G |
NOS3 |
nitric oxide synthase 3 |
decreases activity |
EXP |
potassium ferricyanide results in decreased activity of NOS3 protein |
CTD |
PMID:8810647 |
|
NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
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G |
AKT1 |
AKT serine/threonine kinase 1 |
increases degradation multiple interactions decreases expression |
EXP |
sodium arsenite results in increased degradation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of AKT1 protein]; sodium arsenite results in decreased expression of and results in increased phosphorylation of AKT1 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] sodium arsenite results in decreased expression of AKT1 protein |
CTD |
PMID:12760830 PMID:16239170 |
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
EXP |
bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]; Go 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA] sodium arsenite results in increased expression of HIF1A mRNA; sodium arsenite results in increased expression of HIF1A protein |
CTD |
PMID:15089098 |
|
NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
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G |
MAPK6 |
mitogen-activated protein kinase 6 |
increases expression |
EXP |
sodium arsenite results in increased expression of MAPK6 protein |
CTD |
PMID:12760830 |
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NCBI chr 1:119,725,026...119,770,988
Ensembl chr 1:119,725,029...119,771,312
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G |
NOS3 |
nitric oxide synthase 3 |
multiple interactions increases degradation decreases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of NOS3 protein]; sodium arsenite results in increased phosphorylation of and results in decreased activity of NOS3 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein] sodium arsenite results in decreased expression of NOS3 protein |
CTD |
PMID:16239170 |
|
NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
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G |
PRKACA |
protein kinase cAMP-activated catalytic subunit alpha |
decreases expression |
EXP |
sodium arsenite results in decreased expression of PRKACA protein |
CTD |
PMID:12760830 |
|
NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551
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G |
PRKCD |
protein kinase C delta |
increases phosphorylation |
EXP |
sodium arsenite results in increased phosphorylation of PRKCD protein |
CTD |
PMID:15089098 |
|
NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356
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G |
RPS6KA1 |
ribosomal protein S6 kinase A1 |
decreases expression |
EXP |
sodium arsenite results in decreased expression of RPS6KA1 protein |
CTD |
PMID:12760830 |
|
NCBI chr 6:83,905,124...83,947,189
Ensembl chr 6:83,905,077...83,950,963
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions increases activity |
EXP |
[sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide |
CTD |
PMID:12530527 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
TP53 |
tumor protein p53 |
increases expression |
EXP |
sodium arsenite results in increased expression of TP53 |
CTD |
PMID:13129816 |
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NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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G |
VEGFA |
vascular endothelial growth factor A |
increases expression multiple interactions |
EXP |
sodium arsenite results in increased expression of VEGFA mRNA bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; R 59949 promotes the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; sodium arsenite results in increased expression of and results in increased secretion of VEGFA protein |
CTD |
PMID:15089098 |
|
NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
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G |
DAO |
D-amino acid oxidase |
decreases activity |
EXP |
Sodium Benzoate results in decreased activity of DAO protein |
CTD |
PMID:20952482 |
|
NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,931,541...41,950,633
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G |
CCL2 |
chemokine (C-C motif) ligand 2 |
multiple interactions |
EXP |
sodium borohydride inhibits the reaction [[2,2'-azobis(2-amidinopropane) results in increased oxidation of Docosahexaenoic Acids] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]] |
CTD |
PMID:21130106 |
|
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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G |
AKT1 |
AKT serine/threonine kinase 1 |
decreases expression |
EXP |
sodium bichromate results in decreased expression of AKT1 protein |
CTD |
PMID:12760830 |
|
|
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions |
EXP |
sodium metabisulfite inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA] |
CTD |
PMID:33817499 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
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G |
IL6 |
interleukin 6 |
multiple interactions |
EXP |
sodium metabisulfite inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA] |
CTD |
PMID:33817499 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
EXP |
[Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein |
CTD |
PMID:26582256 |
|
NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
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G |
SLC5A5 |
solute carrier family 5 member 5 |
multiple interactions increases uptake |
EXP |
sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] SLC5A5 protein alternative form results in increased uptake of Sodium Iodide; SLC5A5 protein results in increased uptake of Sodium Iodide |
CTD |
PMID:12586784 |
|
NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266
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G |
SLC5A5 |
solute carrier family 5 member 5 |
multiple interactions |
EXP |
sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] |
CTD |
PMID:12586784 |
|
NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266
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G |
TPO |
thyroid peroxidase |
decreases activity |
EXP |
sodium perchlorate results in decreased activity of TPO protein |
CTD |
PMID:23959146 |
|
NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208
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G |
SLC22A2 |
solute carrier family 22 member 2 |
increases uptake multiple interactions |
EXP |
SLC22A2 protein results in increased uptake of Tetraethylammonium Quercetin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Rutin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] |
CTD |
PMID:19605544 |
|
NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146
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G |
RYR1 |
ryanodine receptor 1 |
increases activity |
EXP |
Thymol results in increased activity of RYR1 protein |
CTD |
PMID:17641978 |
|
NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458
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G |
PSP-I |
porcine seminal protein I |
multiple interactions affects folding |
EXP |
zinc chloride promotes the reaction [PSP-I protein binds to Heparin] zinc chloride affects the folding of PSP-I protein |
CTD |
PMID:16819821 |
|
NCBI chr14:132,302,376...132,309,388
Ensembl chr14:132,302,352...132,308,106
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP |
Zinc Sulfate results in increased expression of BAX mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BAX mRNA] |
CTD |
PMID:28803810 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BECN1 |
beclin 1 |
increases expression multiple interactions |
EXP |
Zinc Sulfate results in increased expression of BECN1 protein 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BECN1 protein] |
CTD |
PMID:28803810 |
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NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
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G |
CASP3 |
caspase 3 |
multiple interactions increases expression increases cleavage |
EXP |
3-methyladenine inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein] Zinc Sulfate results in increased expression of CASP3 mRNA |
CTD |
PMID:28803810 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP6 |
caspase 6 |
increases expression |
EXP |
Zinc Sulfate results in increased expression of CASP6 mRNA |
CTD |
PMID:28803810 |
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NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045
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G |
CASP8 |
caspase 8 |
multiple interactions increases cleavage |
EXP |
3-methyladenine inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP8 protein] |
CTD |
PMID:28803810 |
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NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G |
CYCS |
cytochrome c, somatic |
increases expression multiple interactions |
EXP |
Zinc Sulfate results in increased expression of CYCS mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of CYCS mRNA] |
CTD |
PMID:28803810 |
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NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA] |
CTD |
PMID:32280687 |
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NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in increased expression of IL1B mRNA] |
CTD |
PMID:32280687 |
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G |
MAP1LC3A |
microtubule associated protein 1 light chain 3 alpha |
increases expression |
EXP |
Zinc Sulfate results in increased expression of MAP1LC3A mRNA |
CTD |
PMID:28803810 |
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NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505
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G |
MT1A |
metallothionein 1A |
increases expression |
EXP |
Zinc Sulfate results in increased expression of MT1A mRNA |
CTD |
PMID:25895165 |
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NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:32280687 |
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NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G |
SLC30A1 |
solute carrier family 30 member 1 |
increases expression |
EXP |
Zinc Sulfate results in increased expression of SLC30A1 mRNA |
CTD |
PMID:25895165 |
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NCBI chr 9:131,633,586...131,636,934
Ensembl chr 9:131,633,585...131,640,672
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G |
SLC39A10 |
solute carrier family 39 member 10 |
decreases expression increases expression |
EXP |
Zinc Sulfate results in decreased expression of SLC39A10 mRNA Zinc Sulfate results in increased expression of SLC39A10 mRNA |
CTD |
PMID:16804107 |
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NCBI chr15:99,584,830...99,724,621
Ensembl chr15:99,584,872...99,724,611
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA] |
CTD |
PMID:32280687 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SQSTM1 |
sequestosome 1 |
increases expression multiple interactions decreases expression |
EXP |
Zinc Sulfate results in increased expression of SQSTM1 mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein] |
CTD |
PMID:28803810 |
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NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in increased expression of TNF mRNA] |
CTD |
PMID:32280687 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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