|
G
|
SLC22A5
|
solute carrier family 22 member 5
|
increases uptake
|
EXP
|
SLC22A5 protein results in increased uptake of Carnitine
|
CTD |
PMID:16826461 |
|
NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219
|
|
|
G
|
RUNX2
|
RUNX family transcription factor 2
|
multiple interactions
|
EXP
|
Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]
|
CTD |
PMID:34520801 |
|
NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687
|
|
G
|
SOX5
|
SRY-box transcription factor 5
|
multiple interactions
|
EXP
|
Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]]
|
CTD |
PMID:34520801 |
|
NCBI chr 5:49,159,950...50,166,463
Ensembl chr 5:49,504,551...50,161,558
|
|
|
G
|
CXCL10
|
C-X-C motif chemokine ligand 10
|
increases expression
|
EXP
|
Bethanechol results in increased expression of CXCL10 mRNA
|
CTD |
PMID:29380034 |
|
NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948
|
|
G
|
CXCL8
|
C-X-C motif chemokine ligand 8
|
increases expression
|
EXP
|
Bethanechol results in increased expression of CXCL8 mRNA
|
CTD |
PMID:29380034 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
|
|
G
|
IFNG
|
interferon gamma
|
increases expression
|
EXP
|
Bethanechol results in increased expression of IFNG mRNA
|
CTD |
PMID:29380034 |
|
NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
|
|
G
|
IL17A
|
interleukin 17A
|
increases expression
|
EXP
|
Bethanechol results in increased expression of IL17A mRNA
|
CTD |
PMID:29380034 |
|
NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
|
|
G
|
IL1A
|
interleukin 1 alpha
|
increases expression
|
EXP
|
Bethanechol results in increased expression of IL1A mRNA
|
CTD |
PMID:29380034 |
|
NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121
|
|
|
G
|
BCHE
|
butyrylcholinesterase
|
increases hydrolysis
|
EXP
|
BCHE protein results in increased hydrolysis of butyrylcholine
|
CTD |
PMID:4631366 |
|
NCBI chr13:104,946,732...105,007,568
|
|
|
G
|
BCHE
|
butyrylcholinesterase
|
increases hydrolysis
|
EXP
|
BCHE protein results in increased hydrolysis of Butyrylthiocholine
|
CTD |
PMID:22407886 |
|
NCBI chr13:104,946,732...105,007,568
|
|
|
G
|
CD14
|
CD14 molecule
|
affects expression
|
EXP
|
cadmium nitrate affects the expression of CD14 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581
|
|
G
|
CXCL8
|
C-X-C motif chemokine ligand 8
|
affects expression affects secretion
|
EXP
|
cadmium nitrate affects the expression of CXCL8 mRNA cadmium nitrate affects the secretion of CXCL8 protein
|
CTD |
PMID:29421334 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
|
|
G
|
DEFB1
|
defensin beta 1
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of DEFB1 mRNA
|
CTD |
PMID:29421334 |
|
|
|
G
|
IFNB1
|
interferon beta 1
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of IFNB1 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495
|
|
G
|
IL18
|
interleukin 18
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of IL18 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
|
|
G
|
IL6
|
interleukin 6
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of IL6 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
|
|
G
|
LOC110258578
|
interleukin-1 beta-like
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of IL1B mRNA
|
CTD |
PMID:29421334 |
|
|
|
G
|
MAPK14
|
mitogen-activated protein kinase 14
|
affects expression
|
EXP
|
cadmium nitrate affects the expression of MAPK14 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,877...31,862,031
|
|
G
|
MAPK8
|
mitogen-activated protein kinase 8
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of MAPK8 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874
|
|
G
|
MYD88
|
MYD88 innate immune signal transduction adaptor
|
affects expression
|
EXP
|
cadmium nitrate affects the expression of MYD88 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109
|
|
G
|
NFKB1
|
nuclear factor kappa B subunit 1
|
affects expression
|
EXP
|
cadmium nitrate affects the expression of NFKB1 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
|
|
G
|
RELA
|
RELA proto-oncogene, NF-kB subunit
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of RELA mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
|
|
G
|
SOCS1
|
suppressor of cytokine signaling 1
|
decreases expression
|
EXP
|
cadmium nitrate results in decreased expression of SOCS1 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967
|
|
G
|
STAT3
|
signal transducer and activator of transcription 3
|
decreases expression
|
EXP
|
cadmium nitrate results in decreased expression of STAT3 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
|
|
G
|
TLR4
|
toll like receptor 4
|
affects expression
|
EXP
|
cadmium nitrate affects the expression of TLR4 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
|
|
G
|
TLR5
|
toll like receptor 5
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of TLR5 mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr10:19,387,666...19,410,024
Ensembl chr10:19,387,666...19,410,024
|
|
G
|
TNF
|
tumor necrosis factor
|
increases expression
|
EXP
|
cadmium nitrate results in increased expression of TNF mRNA
|
CTD |
PMID:29421334 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
|
|
|
G
|
ENPEP
|
glutamyl aminopeptidase
|
multiple interactions
|
EXP
|
Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame]
|
CTD |
PMID:8141778 |
|
NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510
|
|
G
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
multiple interactions
|
EXP
|
[Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein
|
CTD |
PMID:26582256 |
|
NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
|
|
|
G
|
SLC22A5
|
solute carrier family 22 member 5
|
decreases activity
|
EXP
|
pivaloylcarnitine results in decreased activity of SLC22A5 protein
|
CTD |
PMID:16826461 |
|
NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219
|
|
|
G
|
CAT
|
catalase
|
multiple interactions
|
EXP
|
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein
|
CTD |
PMID:29129240 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
|
|
G
|
DNMT1
|
DNA methyltransferase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
|
|
G
|
DNMT3A
|
DNA methyltransferase 3 alpha
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
|
|
G
|
GPX1
|
glutathione peroxidase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA
|
CTD |
PMID:29129240 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
|
|
G
|
GYS1
|
glycogen synthase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter
|
CTD |
PMID:29065941 |
|
NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
|
|
G
|
LDHA
|
lactate dehydrogenase A
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter
|
CTD |
PMID:29065941 |
|
NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
|
|
G
|
MTHFR
|
methylenetetrahydrofolate reductase
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
|
|
G
|
SI
|
sucrase-isomaltase
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
|
|
G
|
SLC15A1
|
solute carrier family 15 member 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
|
|
G
|
SLC5A1
|
solute carrier family 5 member 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
|
|
G
|
SOD1
|
superoxide dismutase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA
|
CTD |
PMID:29129240 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
|
|
|
G
|
AOC1
|
amine oxidase copper containing 1
|
affects binding
|
EXP
|
cobaltous chloride binds to AOC1 protein
|
CTD |
PMID:16842785 |
|
NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
|
|
G
|
HSP90B1
|
heat shock protein 90 beta family member 1
|
increases expression
|
EXP
|
cobaltous chloride results in increased expression of HSP90B1 mRNA
|
CTD |
PMID:17464326 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
|
|
G
|
HSPA5
|
heat shock protein family A (Hsp70) member 5
|
increases expression
|
EXP
|
cobaltous chloride results in increased expression of HSPA5 mRNA
|
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
|
|
|
G
|
ADCYAP1
|
adenylate cyclase activating polypeptide 1
|
decreases activity
|
EXP
|
Colforsin results in decreased activity of ADCYAP1 protein alternative form
|
CTD |
PMID:16847435 |
|
NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294
|
|
G
|
ATP7B
|
ATPase copper transporting beta
|
multiple interactions
|
EXP
|
Colforsin inhibits the reaction [Copper binds to ATP7B protein]
|
CTD |
PMID:21084060 |
|
NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
|
|
G
|
CFTR
|
CF transmembrane conductance regulator
|
increases activity
|
EXP
|
Colforsin results in increased activity of CFTR protein
|
CTD |
PMID:15246976 |
|
NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950
|
|
G
|
CREB1
|
cAMP responsive element binding protein 1
|
multiple interactions increases phosphorylation
|
EXP
|
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]
|
CTD |
PMID:17680988 |
|
NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728
|
|
|
G
|
AOC1
|
amine oxidase copper containing 1
|
increases activity
|
EXP
|
cupric chloride results in increased activity of AOC1 protein
|
CTD |
PMID:16842785 |
|
NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
|
|
|
G
|
ABCB10
|
ATP binding cassette subfamily B member 10
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of ABCB10 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of ABCB10 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:60,309,893...60,346,283
Ensembl chr14:60,309,931...60,346,280
|
|
G
|
ACSS1
|
acyl-CoA synthetase short chain family member 1
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of ACSS1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of ACSS1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr17:30,800,536...30,839,799
Ensembl chr17:30,800,427...30,839,742
|
|
G
|
ACSS3
|
acyl-CoA synthetase short chain family member 3
|
multiple interactions decreases expression
|
EXP
|
Quercetin affects the reaction [Copper Sulfate results in decreased expression of ACSS3 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 5:100,272,255...100,429,229
Ensembl chr 5:100,279,698...100,429,165
|
|
G
|
AK4
|
adenylate kinase 4
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of AK4 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:147,177,029...147,257,799
Ensembl chr 6:147,177,029...147,257,814
|
|
G
|
ASPM
|
assembly factor for spindle microtubules
|
affects expression multiple interactions
|
EXP
|
Copper Sulfate affects the expression of ASPM mRNA Quercetin affects the reaction [Copper Sulfate affects the expression of ASPM mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr10:19,971,516...20,039,680
Ensembl chr10:19,975,192...20,039,623
|
|
G
|
ATF1
|
activating transcription factor 1
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of ATF1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of ATF1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 5:16,619,130...16,681,391
Ensembl chr 5:16,618,623...16,681,686
|
|
G
|
ATOX1
|
antioxidant 1 copper chaperone
|
increases expression
|
EXP
|
Copper Sulfate results in increased expression of ATOX1 mRNA
|
CTD |
PMID:22585802 |
|
NCBI chr16:71,299,321...71,314,598
Ensembl chr16:71,299,321...71,314,597
|
|
G
|
BNIP3
|
BCL2 interacting protein 3
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of BNIP3 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907
|
|
G
|
BUB1
|
BUB1 mitotic checkpoint serine/threonine kinase
|
multiple interactions
|
EXP
|
[Quercetin co-treated with Copper Sulfate] results in increased expression of BUB1 mRNA
|
CTD |
PMID:39151877 |
|
NCBI chr 3:45,585,188...45,623,240
Ensembl chr 3:45,585,226...45,624,543
|
|
G
|
CASP1
|
caspase 1, apoptosis-related cysteine peptidase
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of CASP1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
|
|
G
|
CASP3
|
caspase 3
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of CASP3 protein]
|
CTD |
PMID:39151877 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
|
|
G
|
CCNB1
|
cyclin B1
|
increases secretion
|
EXP
|
Copper Sulfate results in increased secretion of CCNB1 protein
|
CTD |
PMID:24521407 |
|
NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
|
|
G
|
CNR1
|
cannabinoid receptor 1
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of CNR1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:56,466,022...56,493,275
Ensembl chr 1:56,467,835...56,492,602
|
|
G
|
COX17
|
cytochrome c oxidase copper chaperone COX17
|
decreases expression
|
EXP
|
Copper Sulfate results in decreased expression of COX17 mRNA
|
CTD |
PMID:22585802 |
|
NCBI chr13:140,584,286...140,594,636
Ensembl chr13:140,584,363...140,587,621
|
|
G
|
COX6B2
|
cytochrome c oxidase subunit 6B2
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of COX6B2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:59,530,419...59,531,770
Ensembl chr 6:59,530,354...59,531,814
|
|
G
|
CPT1B
|
carnitine palmitoyltransferase 1B
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of CPT1B mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of CPT1B mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 5:155,552...163,536
Ensembl chr 5:155,643...163,531
|
|
G
|
CYP1B1
|
cytochrome P450 family 1 subfamily B member 1
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of CYP1B1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of CYP1B1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 3:102,195,743...102,205,687
Ensembl chr 3:102,195,741...102,205,683
|
|
G
|
DAO
|
D-amino acid oxidase
|
multiple interactions decreases expression
|
EXP
|
Quercetin affects the reaction [Copper Sulfate results in decreased expression of DAO mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,931,541...41,950,633
|
|
G
|
DMPK
|
DM1 protein kinase
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of DMPK mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of DMPK mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:52,100,259...52,110,822
Ensembl chr 6:52,100,259...52,110,478
|
|
G
|
DUOX2
|
dual oxidase 2
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of DUOX2 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of DUOX2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:126,620,468...126,641,406
Ensembl chr 1:126,620,510...126,641,406
|
|
G
|
EDNRA
|
endothelin receptor type A
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of EDNRA mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of EDNRA mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853
|
|
G
|
ERBB4
|
erb-b2 receptor tyrosine kinase 4
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of ERBB4 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of ERBB4 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565
|
|
G
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of ERO1A mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of ERO1A mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:182,268,651...182,318,147
Ensembl chr 1:182,265,261...182,318,195
|
|
G
|
FASTKD5
|
FAST kinase domains 5
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of FASTKD5 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of FASTKD5 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr17:32,520,625...32,532,786
Ensembl chr17:32,520,654...32,533,813
|
|
G
|
GARS1
|
glycyl-tRNA synthetase 1
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of GARS1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of GARS1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr18:42,311,711...42,352,201
Ensembl chr18:42,311,576...42,352,162
|
|
G
|
GCLC
|
glutamate-cysteine ligase catalytic subunit
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of GCLC mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
|
|
G
|
GCLM
|
glutamate-cysteine ligase modifier subunit
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of GCLM mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of GCLM mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
|
|
G
|
GHRH
|
growth hormone releasing hormone
|
increases expression
|
EXP
|
Copper Sulfate results in increased expression of GHRH mRNA
|
CTD |
PMID:21110139 |
|
NCBI chr17:40,386,725...40,398,312
Ensembl chr17:40,387,344...40,397,857
|
|
G
|
GSR
|
glutathione-disulfide reductase
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of GSR mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
|
|
G
|
HK2
|
hexokinase 2
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of HK2 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of HK2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 3:68,155,656...68,231,187
Ensembl chr 3:68,153,835...68,231,615
|
|
G
|
HKDC1
|
hexokinase domain containing 1
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of HKDC1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:72,285,941...72,343,990
Ensembl chr14:72,283,845...72,335,886
|
|
G
|
HSD3B1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
|
multiple interactions decreases expression
|
EXP
|
Quercetin affects the reaction [Copper Sulfate results in decreased expression of HSD3B1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 4:101,565,229...101,574,110
|
|
G
|
HSP90B1
|
heat shock protein 90 beta family member 1
|
increases expression
|
EXP
|
Copper Sulfate results in increased expression of HSP90B1 mRNA
|
CTD |
PMID:17464326 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
|
|
G
|
HSPA5
|
heat shock protein family A (Hsp70) member 5
|
increases expression
|
EXP
|
Copper Sulfate results in increased expression of HSPA5 mRNA
|
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
|
|
G
|
HSPA8
|
heat shock protein family A (Hsp70) member 8
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of HSPA8 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of HSPA8 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508
|
|
G
|
IGF1
|
insulin like growth factor 1
|
increases secretion
|
EXP
|
Copper Sulfate results in increased secretion of IGF1 protein
|
CTD |
PMID:24521407 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
|
|
G
|
KDR
|
kinase insert domain receptor
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of KDR mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of KDR mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336
|
|
G
|
KIF11
|
kinesin family member 11
|
multiple interactions
|
EXP
|
[Quercetin co-treated with Copper Sulfate] results in increased expression of KIF11 mRNA
|
CTD |
PMID:39151877 |
|
NCBI chr14:104,125,839...104,177,381
Ensembl chr14:104,125,898...104,177,379
|
|
G
|
LPIN1
|
lipin 1
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of LPIN1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of LPIN1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 3:124,940,557...125,074,137
Ensembl chr 3:124,940,561...125,074,122
|
|
G
|
LRRK2
|
leucine rich repeat kinase 2
|
increases expression
|
EXP
|
Copper Sulfate results in increased expression of LRRK2 mRNA
|
CTD |
PMID:39151877 |
|
NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828
|
|
G
|
MAP3K5
|
mitogen-activated protein kinase kinase kinase 5
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of MAP3K5 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:27,380,143...27,600,500
Ensembl chr 1:27,380,142...27,600,493
|
|
G
|
MGARP
|
mitochondria localized glutamic acid rich protein
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of MGARP mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of MGARP mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 8:87,708,887...87,723,126
Ensembl chr 8:87,697,544...87,723,125
|
|
G
|
MKI67
|
marker of proliferation Ki-67
|
affects expression multiple interactions
|
EXP
|
Copper Sulfate affects the expression of MKI67 mRNA Quercetin affects the reaction [Copper Sulfate affects the expression of MKI67 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:137,266,622...137,296,312
|
|
G
|
MLLT11
|
MLLT11 transcription factor 7 cofactor
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of MLLT11 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 4:98,165,990...98,171,674
Ensembl chr 4:98,164,676...98,171,674
|
|
G
|
MLYCD
|
malonyl-CoA decarboxylase
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of MLYCD mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:4,683,386...4,698,698
Ensembl chr 6:4,681,664...4,698,661
|
|
G
|
MTCP1
|
mature T cell proliferation 1
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of MTCP1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr X:125,372,941...125,377,910
Ensembl chr X:125,377,350...125,381,178
|
|
G
|
NAT8L
|
N-acetyltransferase 8 like
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of NAT8L mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of NAT8L mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 8:1,063,917...1,072,191
Ensembl chr 8:1,063,824...1,072,189
|
|
G
|
NQO1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions increases expression
|
EXP
|
[Quercetin co-treated with Copper Sulfate] results in increased expression of NQO1 mRNA; Quercetin inhibits the reaction [Copper Sulfate results in increased expression of NQO1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
|
|
G
|
PDK4
|
pyruvate dehydrogenase kinase 4
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of PDK4 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:75,246,956...75,260,134
Ensembl chr 9:75,246,002...75,260,134
|
|
G
|
PIF1
|
PIF1 5'-to-3' DNA helicase
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of PIF1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of PIF1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:107,218,580...107,227,171
Ensembl chr 1:107,218,657...107,227,168
|
|
G
|
PLN
|
phospholamban
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of PLN mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:43,449,354...43,458,925
Ensembl chr 1:43,449,354...43,458,925
|
|
G
|
PMAIP1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of PMAIP1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164
|
|
G
|
PPARGC1A
|
PPARG coactivator 1 alpha
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of PPARGC1A mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of PPARGC1A mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992
|
|
G
|
PRDX1
|
peroxiredoxin 1
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of PRDX1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of PRDX1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,395...165,861,442
|
|
G
|
PRDX6
|
peroxiredoxin 6
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of PRDX6 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:115,857,629...115,868,898
Ensembl chr 9:115,857,644...115,868,892
|
|
G
|
PTGS2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of PTGS2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
|
|
G
|
PYCARD
|
PYD and CARD domain containing
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of PYCARD mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
|
|
G
|
RAB38
|
RAB38, member RAS oncogene family
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of RAB38 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of RAB38 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:21,577,083...21,640,637
Ensembl chr 9:21,577,033...21,640,115
|
|
G
|
RCAN1
|
regulator of calcineurin 1
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of RCAN1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of RCAN1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr13:198,106,256...198,205,727
Ensembl chr13:198,102,098...198,205,629
|
|
G
|
SELENOS
|
selenoprotein S
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of SELENOS mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of SELENOS mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:139,829,002...139,836,923
Ensembl chr 1:139,828,791...139,836,914
|
|
G
|
SESN2
|
sestrin 2
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of SESN2 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of SESN2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 6:85,321,982...85,348,044
Ensembl chr 6:85,324,228...85,348,032
|
|
G
|
SLC25A27
|
solute carrier family 25 member 27
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of SLC25A27 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of SLC25A27 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 7:41,426,161...41,457,887
Ensembl chr 7:41,426,170...41,457,883
|
|
G
|
SLC7A11
|
solute carrier family 7 member 11
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of SLC7A11 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 8:88,608,083...88,690,589
Ensembl chr 8:88,608,174...88,687,250
|
|
G
|
SLC8B1
|
solute carrier family 8 member B1
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of SLC8B1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:38,773,396...38,808,261
Ensembl chr14:38,773,407...38,808,265
|
|
G
|
SOD2
|
superoxide dismutase 2
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of SOD2 mRNA Quercetin affects the reaction [Copper Sulfate results in decreased expression of SOD2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
|
|
G
|
SQSTM1
|
sequestosome 1
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of SQSTM1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
|
|
G
|
SRXN1
|
sulfiredoxin 1
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of SRXN1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of SRXN1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr17:34,582,377...34,589,308
Ensembl chr17:34,582,440...34,589,300
|
|
G
|
SST
|
somatostatin
|
decreases expression
|
EXP
|
Copper Sulfate results in decreased expression of SST mRNA; Copper Sulfate results in decreased expression of SST protein
|
CTD |
PMID:21110139 |
|
NCBI chr13:125,337,560...125,338,742
Ensembl chr13:125,337,418...125,338,850
|
|
G
|
STOX1
|
storkhead box 1
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of STOX1 mRNA Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of STOX1 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:71,927,387...71,985,239
Ensembl chr14:71,928,399...71,985,233
|
|
G
|
TGM2
|
transglutaminase 2
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of TGM2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr17:41,186,765...41,221,686
Ensembl chr17:41,186,770...41,221,637
|
|
G
|
TMEM102
|
transmembrane protein 102
|
multiple interactions decreases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in decreased expression of TMEM102 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr12:52,738,942...52,749,326
Ensembl chr12:52,739,238...52,741,322
|
|
G
|
TTK
|
TTK protein kinase
|
multiple interactions affects expression
|
EXP
|
Quercetin affects the reaction [Copper Sulfate affects the expression of TTK mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 1:86,076,576...86,125,334
Ensembl chr 1:86,076,583...86,125,718
|
|
G
|
TXNIP
|
thioredoxin interacting protein
|
decreases expression multiple interactions
|
EXP
|
Copper Sulfate results in decreased expression of TXNIP mRNA Quercetin affects the reaction [Copper Sulfate results in decreased expression of TXNIP mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 4:99,348,589...99,351,760
Ensembl chr 4:99,348,490...99,352,755
|
|
G
|
UBC
|
ubiquitin C
|
multiple interactions increases expression
|
EXP
|
Quercetin inhibits the reaction [Copper Sulfate results in increased expression of UBC mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr14:28,253,857...28,260,771
Ensembl chr14:28,257,027...28,263,044
|
|
G
|
UCP2
|
uncoupling protein 2
|
increases expression multiple interactions
|
EXP
|
Copper Sulfate results in increased expression of UCP2 mRNA Quercetin inhibits the reaction [Copper Sulfate results in increased expression of UCP2 mRNA]
|
CTD |
PMID:39151877 |
|
NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,358,025...8,365,547
|
|
|
G
|
ATF4
|
activating transcription factor 4
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF4 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
|
|
G
|
ATF6
|
activating transcription factor 6
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF6 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
|
|
G
|
BAK1
|
BCL2 antagonist/killer 1
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAK1 protein]
|
CTD |
PMID:26607349 |
|
NCBI chr 7:29,808,849...29,815,345
Ensembl chr 7:29,808,849...29,815,318
|
|
G
|
BAX
|
BCL2 associated X, apoptosis regulator
|
multiple interactions affects expression
|
EXP
|
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAX protein] Sodium Selenite affects the expression of BAX mRNA
|
CTD |
PMID:17342738 PMID:26607349 PMID:37108405 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
|
|
G
|
BCL2
|
BCL2 apoptosis regulator
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]
|
CTD |
PMID:26607349 PMID:37108405 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
|
|
G
|
BCL2L1
|
BCL2 like 1
|
affects expression multiple interactions
|
EXP
|
Sodium Selenite affects the expression of BCL2L1 mRNA Sodium Selenite affects the reaction [bisphenol A results in decreased expression of BCL2L1 protein]
|
CTD |
PMID:17342738 PMID:37108405 |
|
NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
|
|
G
|
CASP3
|
caspase 3
|
multiple interactions decreases expression
|
EXP
|
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP3 protein] Sodium Selenite results in decreased expression of CASP3 protein
|
CTD |
PMID:15191356 PMID:17342738 PMID:26607349 PMID:37108405 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
|
|
G
|
CASP8
|
caspase 8
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP8 mRNA]
|
CTD |
PMID:37108405 |
|
NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
|
|
G
|
CASP9
|
caspase 9
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP9 mRNA]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP9 protein]
|
CTD |
PMID:26607349 PMID:37108405 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
|
|
G
|
CAT
|
catalase
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in decreased activity of CAT protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
|
|
G
|
CLDN1
|
claudin 1
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of CLDN1 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
|
|
G
|
DDIT3
|
DNA damage inducible transcript 3
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
|
|
G
|
EIF2AK3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2AK3 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
|
|
G
|
ERN1
|
endoplasmic reticulum to nucleus signaling 1
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ERN1 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
|
|
G
|
GPX4
|
glutathione peroxidase 4
|
increases activity
|
EXP
|
Sodium Selenite results in increased activity of GPX4 protein
|
CTD |
PMID:10998458 |
|
NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
|
|
G
|
HSPA5
|
heat shock protein family A (Hsp70) member 5
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of HSPA5 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
|
|
G
|
IFNG
|
interferon gamma
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IFNG mRNA]
|
CTD |
PMID:37108405 |
|
NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
|
|
G
|
IL10
|
interleukin 10
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of IL10 mRNA]
|
CTD |
PMID:37108405 |
|
NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
|
|
G
|
IL17A
|
interleukin 17A
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL17A mRNA]
|
CTD |
PMID:37108405 |
|
NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
|
|
G
|
IL6
|
interleukin 6
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA]
|
CTD |
PMID:37108405 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
|
|
G
|
LOC110258578
|
interleukin-1 beta-like
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL1B mRNA]
|
CTD |
PMID:37108405 |
|
|
|
G
|
MAPK1
|
mitogen-activated protein kinase 1
|
increases expression
|
EXP
|
Sodium Selenite results in increased expression of MAPK1 protein
|
CTD |
PMID:17342738 |
|
NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
|
|
G
|
MAPK3
|
mitogen-activated protein kinase 3
|
increases expression
|
EXP
|
Sodium Selenite results in increased expression of MAPK3 protein
|
CTD |
PMID:17342738 |
|
NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
|
|
G
|
MIR125A
|
microRNA mir-125a
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]; Sodium Selenite inhibits the reaction [Cadmium results in decreased expression of MIR125A mRNA]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [MIR125A mRNA mutant form results in increased expression of CASP9 protein]
|
CTD |
PMID:26607349 |
|
NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
|
|
G
|
OCLN
|
occludin
|
multiple interactions
|
EXP
|
Sodium Selenite affects the reaction [bisphenol A results in decreased expression of OCLN protein]
|
CTD |
PMID:37108405 |
|
NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
|
|
G
|
POMC
|
proopiomelanocortin
|
multiple interactions
|
EXP
|
Ditiocarb promotes the reaction [Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]]; Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]
|
CTD |
PMID:21466817 |
|
NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
|
|
G
|
TJP1
|
tight junction protein 1
|
multiple interactions
|
EXP
|
Sodium Selenite affects the reaction [bisphenol A results in decreased expression of TJP1 protein]
|
CTD |
PMID:37108405 |
|
NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
|
|
G
|
TNF
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]
|
CTD |
PMID:37108405 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
|
|
|
G
|
ABCB1
|
ATP-binding cassette, sub-family B (MDR/TAP), member 1
|
affects expression
|
EXP
|
flunixin meglumine affects the expression of ABCB1 mRNA
|
CTD |
PMID:26366864 |
|
NCBI chr 9:93,049,955...93,146,469
|
|
G
|
CYP1A2
|
cytochrome P450 family 1 subfamily A member 2
|
affects expression
|
EXP
|
flunixin meglumine affects the expression of CYP1A2 mRNA
|
CTD |
PMID:26366864 |
|
NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100
|
|
G
|
CYP2E1
|
cytochrome P450 family 2 subfamily E member 1
|
affects expression
|
EXP
|
flunixin meglumine affects the expression of CYP2E1 mRNA
|
CTD |
PMID:26366864 |
|
NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817
|
|
G
|
CYP3A22
|
cytochrome P450 family 3 subfamily A member 22
|
affects expression
|
EXP
|
flunixin meglumine affects the expression of CYP3A22 mRNA
|
CTD |
PMID:26366864 |
|
NCBI chr 3:6,617,256...6,665,179
Ensembl chr 3:6,615,343...6,822,817
|
|
G
|
CYP3A29
|
cytochrome P450 family 3 subfamily A member 29
|
affects expression
|
EXP
|
flunixin meglumine affects the expression of CYP3A29 mRNA
|
CTD |
PMID:26366864 |
|
NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
|
|
G
|
SULT1A3
|
sulfotransferase family 1A member 3
|
affects expression
|
EXP
|
flunixin meglumine affects the expression of SULT1A1 mRNA
|
CTD |
PMID:26366864 |
|
NCBI chr 3:18,351,205...18,354,653
Ensembl chr 3:18,351,194...18,354,649
|
|
|
G
|
ATF4
|
activating transcription factor 4
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein]
|
CTD |
PMID:36584959 |
|
NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
|
|
G
|
ATF6
|
activating transcription factor 6
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of ATF6 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
|
|
G
|
BAX
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
EXP
|
[Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA
|
CTD |
PMID:36584959 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
|
|
G
|
CASP3
|
caspase 3
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of CASP3 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
|
|
G
|
CASP9
|
caspase 9
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
|
|
G
|
CAT
|
catalase
|
multiple interactions
|
EXP
|
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein; Betaine inhibits the reaction [Glyphosate results in increased expression of CAT mRNA]
|
CTD |
PMID:29129240 PMID:36584959 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
|
|
G
|
CLDN1
|
claudin 1
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein]
|
CTD |
PMID:36584959 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
|
|
G
|
DDIT3
|
DNA damage inducible transcript 3
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
|
|
G
|
DNMT1
|
DNA methyltransferase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
|
|
G
|
DNMT3A
|
DNA methyltransferase 3 alpha
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
|
|
G
|
EIF2AK3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 protein]
|
CTD |
PMID:36584959 |
|
NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
|
|
G
|
EIF2S1
|
eukaryotic translation initiation factor 2 subunit alpha
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 protein]
|
CTD |
PMID:36584959 |
|
NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827
|
|
G
|
ERN1
|
endoplasmic reticulum to nucleus signaling 1
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of ERN1 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
|
|
G
|
GPX1
|
glutathione peroxidase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA
|
CTD |
PMID:29129240 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
|
|
G
|
GPX2
|
glutathione peroxidase 2
|
multiple interactions
|
EXP
|
[Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA
|
CTD |
PMID:36584959 |
|
NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
|
|
G
|
GYS1
|
glycogen synthase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter
|
CTD |
PMID:29065941 |
|
NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
|
|
G
|
HSP90B1
|
heat shock protein 90 beta family member 1
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 protein]
|
CTD |
PMID:36584959 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
|
|
G
|
LDHA
|
lactate dehydrogenase A
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter
|
CTD |
PMID:29065941 |
|
NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
|
|
G
|
MFN1
|
mitofusin 1
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
|
|
G
|
MTHFR
|
methylenetetrahydrofolate reductase
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
|
|
G
|
NFE2L2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of NFE2L2 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
|
|
G
|
NQO1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
|
|
G
|
PCNA
|
proliferating cell nuclear antigen
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA protein]
|
CTD |
PMID:36584959 |
|
NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
|
|
G
|
SDHA
|
succinate dehydrogenase complex flavoprotein subunit A
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
|
|
G
|
SI
|
sucrase-isomaltase
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
|
|
G
|
SLC15A1
|
solute carrier family 15 member 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
|
|
G
|
SLC5A1
|
solute carrier family 5 member 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA
|
CTD |
PMID:28445388 |
|
NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
|
|
G
|
SOD1
|
superoxide dismutase 1
|
multiple interactions
|
EXP
|
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA
|
CTD |
PMID:29129240 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
|
|
G
|
SOD2
|
superoxide dismutase 2
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of SOD2 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
|
|
G
|
UQCRB
|
ubiquinol-cytochrome c reductase binding protein
|
multiple interactions
|
EXP
|
[Betaine co-treated with Glyphosate] results in decreased expression of UQCRB mRNA
|
CTD |
PMID:36584959 |
|
NCBI chr 4:40,403,272...40,409,080
Ensembl chr 4:40,403,109...40,409,057
|
|
G
|
XBP1
|
X-box binding protein 1
|
multiple interactions
|
EXP
|
Betaine inhibits the reaction [Glyphosate results in increased expression of XBP1 mRNA]
|
CTD |
PMID:36584959 |
|
NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
|
|
|
G
|
AKT1
|
AKT serine/threonine kinase 1
|
increases expression
|
EXP
|
lead acetate results in increased expression of AKT1 mRNA
|
CTD |
PMID:29273543 |
|
|
|
G
|
AMH
|
anti-Mullerian hormone
|
decreases expression multiple interactions
|
EXP
|
lead acetate results in decreased expression of AMH mRNA lead acetate results in decreased expression of and results in decreased secretion of AMH protein
|
CTD |
PMID:29273543 |
|
NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,414,427...76,418,312
|
|
G
|
FSHB
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol]
|
CTD |
PMID:29273543 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
|
|
G
|
FSHR
|
follicle stimulating hormone receptor
|
decreases expression
|
EXP
|
lead acetate results in decreased expression of FSHR mRNA
|
CTD |
PMID:29273543 |
|
NCBI chr 3:91,607,236...91,775,255
Ensembl chr 3:91,607,305...91,774,683
|
|
G
|
HSP90B1
|
heat shock protein 90 beta family member 1
|
increases expression
|
EXP
|
lead acetate results in increased expression of HSP90B1 mRNA
|
CTD |
PMID:17464326 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
|
|
G
|
HSPA5
|
heat shock protein family A (Hsp70) member 5
|
increases expression
|
EXP
|
lead acetate results in increased expression of HSPA5 mRNA
|
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
|
|
G
|
INHA
|
inhibin subunit alpha
|
multiple interactions
|
EXP
|
lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein]
|
CTD |
PMID:29273543 |
|
NCBI chr15:121,581,847...121,586,020
Ensembl chr15:121,580,803...121,586,006
|
|
G
|
INHBB
|
inhibin subunit beta B
|
decreases expression multiple interactions
|
EXP
|
lead acetate results in decreased expression of INHBB mRNA lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein]; lead acetate results in decreased expression of and results in decreased secretion of INHBB protein
|
CTD |
PMID:29273543 |
|
NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405
|
|
G
|
MTOR
|
mechanistic target of rapamycin kinase
|
increases expression
|
EXP
|
lead acetate results in increased expression of MTOR mRNA
|
CTD |
PMID:29273543 |
|
NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
|
|
|
G
|
CHRM2
|
cholinergic receptor muscarinic 2
|
multiple interactions
|
EXP
|
methoctramine inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM2 protein]
|
CTD |
PMID:8744975 |
|
NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186
|
|
|
G
|
ACACA
|
acetyl-CoA carboxylase alpha
|
increases expression multiple interactions
|
EXP
|
Sodium Glutamate results in increased expression of ACACA mRNA Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of ACACA mRNA]
|
CTD |
PMID:31360149 |
|
NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712
|
|
G
|
ACOX1
|
acyl-CoA oxidase 1
|
increases expression
|
EXP
|
Sodium Glutamate results in increased expression of ACOX1 mRNA
|
CTD |
PMID:31360149 |
|
NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546
|
|
G
|
FASN
|
fatty acid synthase
|
multiple interactions increases expression
|
EXP
|
Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of FASN mRNA]
|
CTD |
PMID:31360149 |
|
NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561
|
|
G
|
FFAR1
|
free fatty acid receptor 1
|
affects expression
|
EXP
|
Sodium Glutamate affects the expression of FFAR1 mRNA
|
CTD |
PMID:31360149 |
|
NCBI chr 6:44,837,764...44,841,518
|
|
G
|
FFAR2
|
free fatty acid receptor 2
|
multiple interactions affects expression
|
EXP
|
Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR2 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR2 mRNA]
|
CTD |
PMID:31360149 |
|
NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,901,159...44,904,459
|
|
G
|
FFAR4
|
free fatty acid receptor 4
|
affects expression multiple interactions
|
EXP
|
Sodium Glutamate affects the expression of FFAR4 mRNA Dietary Fats affects the reaction [Sodium Glutamate affects the expression of FFAR4 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of FFAR4 mRNA]
|
CTD |
PMID:31360149 |
|
Ensembl chr14:105,011,942...105,037,498
|
|
G
|
GPR119
|
G protein-coupled receptor 119
|
affects expression multiple interactions
|
EXP
|
Sodium Glutamate affects the expression of GPR119 mRNA Dietary Fats affects the reaction [Sodium Glutamate affects the expression of GPR119 mRNA]; Sodium Glutamate affects the reaction [Dietary Fats affects the expression of GPR119 mRNA]
|
CTD |
PMID:31360149 |
|
NCBI chr X:106,872,225...106,873,299
Ensembl chr X:106,872,225...106,873,299
|
|
G
|
LOC110255234
|
liver carboxylesterase-like
|
multiple interactions
|
EXP
|
Sodium Glutamate inhibits the reaction [Dietary Fats results in decreased expression of CES1 mRNA]
|
CTD |
PMID:31360149 |
|
|
|
G
|
PNPLA2
|
patatin like phospholipase domain containing 2
|
increases expression
|
EXP
|
Sodium Glutamate results in increased expression of PNPLA2 mRNA
|
CTD |
PMID:31360149 |
|
NCBI chr 2:513,065...517,962
Ensembl chr 2:513,077...518,182
|
|
G
|
SREBF1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions increases expression
|
EXP
|
Dietary Fats inhibits the reaction [Sodium Glutamate results in increased expression of SREBF1 mRNA]
|
CTD |
PMID:31360149 |
|
NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267
|
|
|
G
|
SLC22A5
|
solute carrier family 22 member 5
|
increases uptake
|
EXP
|
SLC22A5 protein results in increased uptake of Acetylcarnitine
|
CTD |
PMID:16826461 |
|
NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219
|
|
|
G
|
ABCB4
|
ATP binding cassette subfamily B member 4
|
increases export multiple interactions
|
EXP
|
ABCB4 protein results in increased export of Phosphatidylcholines Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]
|
CTD |
PMID:21056966 |
|
NCBI chr 9:93,171,371...93,262,124
|
|
G
|
PDIA3
|
protein disulfide isomerase family A member 3
|
increases hydrolysis
|
EXP
|
PDIA3 protein results in increased hydrolysis of Phosphatidylcholines
|
CTD |
PMID:16798117 |
|
NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
|
|
|
G
|
CCNB1
|
cyclin B1
|
multiple interactions
|
EXP
|
pifithrin inhibits the reaction [deoxynivalenol results in decreased expression of CCNB1 protein]
|
CTD |
PMID:38104654 |
|
NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
|
|
G
|
CDK1
|
cyclin dependent kinase 1
|
multiple interactions
|
EXP
|
pifithrin inhibits the reaction [deoxynivalenol results in decreased expression of CDK1 protein]
|
CTD |
PMID:38104654 |
|
NCBI chr14:64,233,945...64,255,290
Ensembl chr14:64,233,987...64,372,197
|
|
|
G
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
decreases activity
|
EXP
|
potassium chromate(VI) results in decreased activity of GAPDH protein
|
CTD |
PMID:26582256 |
|
NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
|
|
|
G
|
NOS3
|
nitric oxide synthase 3
|
decreases activity
|
EXP
|
potassium ferricyanide results in decreased activity of NOS3 protein
|
CTD |
PMID:8810647 |
|
NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
|
|
|
G
|
AHR
|
aryl hydrocarbon receptor
|
multiple interactions
|
EXP
|
AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3A mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol affects the localization of AHR protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]
|
CTD |
PMID:35381244 |
|
NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
|
|
G
|
AKT1
|
AKT serine/threonine kinase 1
|
increases degradation multiple interactions decreases expression
|
EXP
|
sodium arsenite results in increased degradation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of AKT1 protein]; sodium arsenite results in decreased expression of and results in increased phosphorylation of AKT1 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] sodium arsenite results in decreased expression of AKT1 protein
|
CTD |
PMID:12760830 PMID:16239170 |
|
|
|
G
|
ARNT
|
aryl hydrocarbon receptor nuclear translocator
|
multiple interactions
|
EXP
|
AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ARNT mRNA]
|
CTD |
PMID:35381244 |
|
NCBI chr 4:98,333,431...98,390,012
Ensembl chr 4:98,333,459...98,389,457
|
|
G
|
ATG5
|
autophagy related 5
|
multiple interactions
|
EXP
|
6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]
|
CTD |
PMID:35381244 |
|
NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396
|
|
G
|
BECN1
|
beclin 1
|
multiple interactions
|
EXP
|
6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]
|
CTD |
PMID:35381244 |
|
NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
|
|
G
|
CLDN1
|
claudin 1
|
multiple interactions
|
EXP
|
6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]
|
CTD |
PMID:35381244 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
|
|
G
|
CYP1A1
|
cytochrome P450 family 1 subfamily A member 1
|
multiple interactions
|
EXP
|
AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:35381244 |
|
NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
|
|
G
|
HIF1A
|
hypoxia inducible factor 1 subunit alpha
|
multiple interactions increases expression
|
EXP
|
bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]; Go 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA] sodium arsenite results in increased expression of HIF1A mRNA; sodium arsenite results in increased expression of HIF1A protein
|
CTD |
PMID:15089098 |
|
NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
|
|
G
|
MAP1LC3A
|
microtubule associated protein 1 light chain 3 alpha
|
multiple interactions
|
EXP
|
6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3A mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3A mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3A mRNA]
|
CTD |
PMID:35381244 |
|
NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505
|
|
G
|
MAPK6
|
mitogen-activated protein kinase 6
|
increases expression
|
EXP
|
sodium arsenite results in increased expression of MAPK6 protein
|
CTD |
PMID:12760830 |
|
NCBI chr 1:119,725,026...119,770,988
Ensembl chr 1:119,725,029...119,771,312
|
|
G
|
NOS3
|
nitric oxide synthase 3
|
multiple interactions increases degradation decreases expression
|
EXP
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of NOS3 protein]; sodium arsenite results in increased phosphorylation of and results in decreased activity of NOS3 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein] sodium arsenite results in decreased expression of NOS3 protein
|
CTD |
PMID:16239170 |
|
NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
|
|
G
|
OCLN
|
occludin
|
multiple interactions
|
EXP
|
6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN protein]
|
CTD |
PMID:35381244 |
|
NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
|
|
G
|
PRKACA
|
protein kinase cAMP-activated catalytic subunit alpha
|
decreases expression
|
EXP
|
sodium arsenite results in decreased expression of PRKACA protein
|
CTD |
PMID:12760830 |
|
NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551
|
|
G
|
PRKCD
|
protein kinase C delta
|
increases phosphorylation
|
EXP
|
sodium arsenite results in increased phosphorylation of PRKCD protein
|
CTD |
PMID:15089098 |
|
NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356
|
|
G
|
RPS6KA1
|
ribosomal protein S6 kinase A1
|
decreases expression
|
EXP
|
sodium arsenite results in decreased expression of RPS6KA1 protein
|
CTD |
PMID:12760830 |
|
NCBI chr 6:83,905,124...83,947,189
Ensembl chr 6:83,905,077...83,950,963
|
|
G
|
SOD1
|
superoxide dismutase 1
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multiple interactions increases activity
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EXP
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[sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide
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CTD |
PMID:12530527 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G
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TJP1
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tight junction protein 1
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multiple interactions
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EXP
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6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; AHR protein affects the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]
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CTD |
PMID:35381244 |
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NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G
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TP53
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tumor protein p53
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increases expression
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EXP
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sodium arsenite results in increased expression of TP53
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CTD |
PMID:13129816 |
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NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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G
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VEGFA
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vascular endothelial growth factor A
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increases expression multiple interactions
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EXP
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sodium arsenite results in increased expression of VEGFA mRNA bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; R 59949 promotes the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; sodium arsenite results in increased expression of and results in increased secretion of VEGFA protein
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CTD |
PMID:15089098 |
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NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
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G
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DAO
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D-amino acid oxidase
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decreases activity
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EXP
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Sodium Benzoate results in decreased activity of DAO protein
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CTD |
PMID:20952482 |
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NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,931,541...41,950,633
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G
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CCL2
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chemokine (C-C motif) ligand 2
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multiple interactions
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EXP
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sodium borohydride inhibits the reaction [[2,2'-azobis(2-amidinopropane) results in increased oxidation of Docosahexaenoic Acids] inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 mRNA]]
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CTD |
PMID:21130106 |
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NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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G
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FFAR1
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free fatty acid receptor 1
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multiple interactions
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EXP
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Dietary Fats affects the reaction [Sodium Chloride affects the expression of FFAR1 mRNA]; Sodium Chloride affects the reaction [Dietary Fats affects the expression of FFAR1 mRNA]
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CTD |
PMID:31360149 |
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NCBI chr 6:44,837,764...44,841,518
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G
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AKT1
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AKT serine/threonine kinase 1
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decreases expression
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EXP
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sodium bichromate results in decreased expression of AKT1 protein
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CTD |
PMID:12760830 |
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G
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CXCL8
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C-X-C motif chemokine ligand 8
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multiple interactions
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EXP
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sodium metabisulfite inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]
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CTD |
PMID:33817499 |
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NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
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G
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IL6
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interleukin 6
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multiple interactions
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EXP
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sodium metabisulfite inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]
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CTD |
PMID:33817499 |
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NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G
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GAPDH
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glyceraldehyde-3-phosphate dehydrogenase
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multiple interactions
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EXP
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[Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein
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CTD |
PMID:26582256 |
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NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
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G
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SLC5A5
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solute carrier family 5 member 5
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multiple interactions increases uptake
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EXP
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sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] SLC5A5 protein alternative form results in increased uptake of Sodium Iodide; SLC5A5 protein results in increased uptake of Sodium Iodide
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CTD |
PMID:12586784 |
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NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266
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G
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SLC5A5
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solute carrier family 5 member 5
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multiple interactions
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EXP
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sodium perchlorate inhibits the reaction [SLC5A5 protein alternative form results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]
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CTD |
PMID:12586784 |
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NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266
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G
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TPO
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thyroid peroxidase
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decreases activity
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EXP
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sodium perchlorate results in decreased activity of TPO protein
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CTD |
PMID:23959146 |
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NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208
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G
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SLC22A2
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solute carrier family 22 member 2
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increases uptake multiple interactions
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EXP
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SLC22A2 protein results in increased uptake of Tetraethylammonium Quercetin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]; Rutin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]
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CTD |
PMID:19605544 |
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NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146
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G
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RYR1
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ryanodine receptor 1
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increases activity
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EXP
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Thymol results in increased activity of RYR1 protein
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CTD |
PMID:17641978 |
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NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458
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G
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PSP-I
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porcine seminal protein I
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multiple interactions affects folding
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EXP
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zinc chloride promotes the reaction [PSP-I protein binds to Heparin] zinc chloride affects the folding of PSP-I protein
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CTD |
PMID:16819821 |
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NCBI chr14:132,302,376...132,309,388
Ensembl chr14:132,302,352...132,308,106
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G
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BAX
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BCL2 associated X, apoptosis regulator
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increases expression multiple interactions
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EXP
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Zinc Sulfate results in increased expression of BAX mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BAX mRNA]
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CTD |
PMID:28803810 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G
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BECN1
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beclin 1
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increases expression multiple interactions
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EXP
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Zinc Sulfate results in increased expression of BECN1 protein 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BECN1 protein]
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CTD |
PMID:28803810 |
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NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
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G
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CASP3
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caspase 3
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multiple interactions increases expression increases cleavage
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EXP
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3-methyladenine inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein] Zinc Sulfate results in increased expression of CASP3 mRNA
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CTD |
PMID:28803810 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G
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CASP6
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caspase 6
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increases expression
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EXP
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Zinc Sulfate results in increased expression of CASP6 mRNA
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CTD |
PMID:28803810 |
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NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045
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G
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CASP8
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caspase 8
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multiple interactions increases cleavage
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EXP
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3-methyladenine inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP8 protein]
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CTD |
PMID:28803810 |
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NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G
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CYCS
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cytochrome c, somatic
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increases expression multiple interactions
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EXP
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Zinc Sulfate results in increased expression of CYCS mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of CYCS mRNA]
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CTD |
PMID:28803810 |
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NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
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G
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GPX1
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glutathione peroxidase 1
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multiple interactions
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EXP
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Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA]
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CTD |
PMID:32280687 |
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NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G
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HSPA6
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heat shock protein family A (Hsp70) member 6
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increases expression
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EXP
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Zinc Sulfate results in increased expression of HSP70 mRNA
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CTD |
PMID:23274768 |
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NCBI chr 4:88,970,592...88,973,109
Ensembl chr 4:88,970,599...88,973,918
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G
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LOC110258578
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interleukin-1 beta-like
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multiple interactions
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EXP
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Zinc Sulfate inhibits the reaction [Diquat results in increased expression of IL1B mRNA]
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CTD |
PMID:32280687 |
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G
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MAP1LC3A
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microtubule associated protein 1 light chain 3 alpha
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increases expression
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EXP
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Zinc Sulfate results in increased expression of MAP1LC3A mRNA
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CTD |
PMID:28803810 |
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NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505
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G
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MT1A
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metallothionein 1A
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increases expression
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EXP
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Zinc Sulfate results in increased expression of MT1A mRNA
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CTD |
PMID:25895165 |
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NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672
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G
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NFE2L2
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NFE2 like bZIP transcription factor 2
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multiple interactions
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EXP
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Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA]
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CTD |
PMID:32280687 |
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NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G
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SLC30A1
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solute carrier family 30 member 1
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increases expression
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EXP
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Zinc Sulfate results in increased expression of SLC30A1 mRNA
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CTD |
PMID:25895165 |
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NCBI chr 9:131,633,586...131,636,934
Ensembl chr 9:131,633,585...131,640,672
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G
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SLC39A10
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solute carrier family 39 member 10
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decreases expression increases expression
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EXP
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Zinc Sulfate results in decreased expression of SLC39A10 mRNA Zinc Sulfate results in increased expression of SLC39A10 mRNA
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CTD |
PMID:16804107 |
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NCBI chr15:99,584,830...99,724,621
Ensembl chr15:99,584,872...99,724,611
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G
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SOD1
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superoxide dismutase 1
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multiple interactions
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EXP
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Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA]
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CTD |
PMID:32280687 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G
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SQSTM1
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sequestosome 1
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increases expression multiple interactions decreases expression
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EXP
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Zinc Sulfate results in increased expression of SQSTM1 mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein]
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CTD |
PMID:28803810 |
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NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
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G
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TNF
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tumor necrosis factor
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multiple interactions
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EXP
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Zinc Sulfate inhibits the reaction [Diquat results in increased expression of TNF mRNA]
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CTD |
PMID:32280687 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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