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G |
TPO |
thyroid peroxidase |
decreases activity |
EXP |
captax results in decreased activity of TPO protein |
CTD |
PMID:23959146 PMID:25953703 |
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NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,408,943
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
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NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,296...129,713,729
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Dithiothreitol metabolite results in increased expression of HSPA5 protein |
CTD |
PMID:17416481 |
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NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
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G |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] |
CTD |
PMID:16785314 |
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NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,606...55,681,426
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G |
FMO1 |
flavin containing dimethylaniline monoxygenase 1 |
increases metabolic processing |
EXP |
FMO1 protein results in increased metabolism of Cysteamine |
CTD |
PMID:6439199 |
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NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,812,103...63,895,077
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G |
INS |
insulin |
multiple interactions |
EXP |
Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]] |
CTD |
PMID:1928324 |
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NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
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G |
AQP1 |
aquaporin 1 (Colton blood group) |
increases transport multiple interactions |
EXP |
AQP1 protein results in increased transport of Water Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water] |
CTD |
PMID:16534851 |
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NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,481...42,076,746
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G |
AGT |
angiotensinogen |
decreases activity |
EXP |
Enalaprilat results in decreased activity of AGT protein modified form |
CTD |
PMID:7890486 |
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NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
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G |
KNG1 |
kininogen 1 |
increases activity |
EXP |
Enalaprilat results in increased activity of KNG1 protein modified form |
CTD |
PMID:7890486 |
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NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,277...124,557,376
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G |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] |
CTD |
PMID:16785314 |
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NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,606...55,681,426
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G |
LOC100739163 |
glutathione S-transferase P-like |
multiple interactions |
EXP |
GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione] |
CTD |
PMID:14573868 |
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NCBI chr 2:4,978,761...4,982,233
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G |
MT3 |
metallothionein 3 |
multiple interactions |
EXP |
MT3 protein binds to and affects the metabolism of Hydroxyl Radical |
CTD |
PMID:12680700 |
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NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,721...18,789,137
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
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NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,296...129,713,729
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Dithiothreitol metabolite results in increased expression of HSPA5 protein |
CTD |
PMID:17416481 |
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NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
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G |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] |
CTD |
PMID:16785314 |
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NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,606...55,681,426
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
Mercaptoethanol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
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NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,296...129,713,729
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G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
EXP |
2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Wortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
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NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
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G |
PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
EXP |
PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
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NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,434,873...46,523,609
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G |
CASP3 |
caspase 3 |
increases activity |
EXP |
Tacrolimus results in increased activity of CASP3 protein |
CTD |
PMID:14675044 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
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G |
AQP1 |
aquaporin 1 (Colton blood group) |
increases transport multiple interactions |
EXP |
AQP1 protein results in increased transport of Water Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water] |
CTD |
PMID:16534851 |
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NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,481...42,076,746
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