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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:elemental bromine
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Accession:CHEBI:36894 term browser browse the term


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3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases reduction
multiple interactions
ISO NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
CTD PMID:29281794 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
dibromine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator decreases activity ISO Bromine results in decreased activity of CFTR protein CTD PMID:15286085 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
NAN 190 hydrobromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:15213358 PMID:15482641 PMID:16528294 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
sodium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m] CTD PMID:12488351 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
tiotropium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 affects binding ISO Tiotropium Bromide binds to CHRM1 protein CTD PMID:21870878 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects binding ISO Tiotropium Bromide binds to CHRM2 protein CTD PMID:21870878 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 affects binding ISO Tiotropium Bromide binds to CHRM3 protein CTD PMID:21870878 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects binding ISO Tiotropium Bromide binds to CHRM4 protein CTD PMID:21870878 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 affects binding ISO Tiotropium Bromide binds to CHRM5 protein CTD PMID:21870878 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Tiotropium Bromide inhibits the reaction [Oxotremorine results in increased expression of EDN1 mRNA] CTD PMID:22796455 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Tiotropium Bromide results in decreased activity of PON1 protein CTD PMID:31581362 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO Tiotropium Bromide results in decreased secretion of TNF protein CTD PMID:21352583 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
tiquizium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO thiaton results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:11855677 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
vecuronium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCA1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCA1 protein] CTD PMID:30036686 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCG1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCG1 protein] CTD PMID:30036686 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM1 protein] CTD PMID:9846649 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM2 protein] CTD PMID:9846649 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM3 protein] CTD PMID:9846649 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM4 protein] CTD PMID:9846649 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM5 protein] CTD PMID:9846649 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 PMID:16931985 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein] CTD PMID:16931985 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 PMID:16931985 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP11A1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP11A1 protein] CTD PMID:31846720 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP19A1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP19A1 protein] CTD PMID:30959089 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of EGR1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of EGR1 protein] CTD PMID:29486207 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of ELK1 protein] CTD PMID:29486207 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Hdac4 histone deacetylase 4 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of HDAC4 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of HDAC4 protein] CTD PMID:31846720 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO Vecuronium Bromide results in increased secretion of HEXB protein CTD PMID:19758318 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression
multiple interactions
ISO Vecuronium Bromide results in increased expression of HSD11B2 mRNA; Vecuronium Bromide results in increased expression of HSD11B2 protein
Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 protein]
CTD PMID:29486207 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] CTD PMID:29486207 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] CTD PMID:29486207 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 protein] CTD PMID:30036686 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H3 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H3 protein] CTD PMID:30036686 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of SCARB1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of SCARB1 protein] CTD PMID:30036686 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of STAR mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of STAR protein] CTD PMID:31846720 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link

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  CHEBI ontology 19853
    chemical entity 19853
      molecular entity 19851
        elemental molecular entity 16328
          elemental halogen 9253
            elemental bromine 40
              diatomic bromine + 1
              monoatomic bromine + 39
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