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G |
Ar |
androgen receptor |
affects binding |
EXP |
2-hydroxyestradiol binds to AR protein |
CTD |
PMID:14565775 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Ccnd1 |
cyclin D1 |
increases expression |
ISO |
2-hydroxyestradiol results in increased expression of CCND1 protein |
CTD |
PMID:23685341 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ckb |
creatine kinase B |
multiple interactions |
EXP |
2-hydroxyestradiol inhibits the reaction [Estradiol results in increased expression of CKB] |
CTD |
PMID:10030690 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Comt |
catechol-O-methyltransferase |
increases methylation affects metabolic processing |
ISO EXP |
COMT protein results in increased methylation of 2-hydroxyestradiol COMT protein affects the metabolism of 2-hydroxyestradiol |
CTD |
PMID:11160877 PMID:15377160 |
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NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
affects chemical synthesis multiple interactions |
ISO |
CYP1A1 protein affects the chemical synthesis of 2-hydroxyestradiol [CYP1A1 protein results in increased oxidation of Estradiol] which results in increased chemical synthesis of 2-hydroxyestradiol; Resveratrol inhibits the reaction [CYP1A1 protein affects the chemical synthesis of 2-hydroxyestradiol] 2-hydroxyestradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] |
CTD |
PMID:12093619 PMID:15142886 PMID:32781018 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases chemical synthesis multiple interactions |
ISO |
CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol Carbaryl inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]; Chlorpyrifos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]; Fonofos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]; naphthalene inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol] |
CTD |
PMID:16790556 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
CYP1B1 protein affects the metabolism of [2-hydroxyestradiol co-treated with Glutathione] |
CTD |
PMID:14679015 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases chemical synthesis |
ISO |
Chlorpyrifos inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 2-hydroxyestradiol]; decamethrin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 2-hydroxyestradiol]; Fonofos inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 2-hydroxyestradiol]; Permethrin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 2-hydroxyestradiol] |
CTD |
PMID:16790556 |
|
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
2-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] |
CTD |
PMID:9048584 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions decreases expression |
EXP ISO |
2-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein] 2-hydroxyestradiol results in decreased expression of ESR2 protein |
CTD |
PMID:9048584 PMID:23685341 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Foxo1 |
forkhead box O1 |
decreases expression |
ISO |
2-hydroxyestradiol results in decreased expression of FOXO1 protein |
CTD |
PMID:23685341 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
increases expression multiple interactions |
ISO |
2-hydroxyestradiol results in increased expression of IGFBP1 mRNA 2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA] |
CTD |
PMID:32781018 |
|
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
increases expression |
ISO |
2-hydroxyestradiol results in increased expression of ATP6 mRNA |
CTD |
PMID:9886577 |
|
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
increases expression |
ISO |
2-hydroxyestradiol results in increased expression of COX3 mRNA |
CTD |
PMID:9886577 |
|
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
ISO |
2-hydroxyestradiol results in increased expression of MYC protein |
CTD |
PMID:23685341 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Prl |
prolactin |
increases expression multiple interactions |
ISO |
2-hydroxyestradiol results in increased expression of PRL mRNA 2-hydroxyestradiol promotes the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA] |
CTD |
PMID:32781018 |
|
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA; Acetylcysteine inhibits the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Estradiol promotes the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]]; BAY 11-7085 inhibits the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]; BAY 11-7085 inhibits the reaction [Estradiol promotes the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]]; Estradiol promotes the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA] |
CTD |
PMID:18480072 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Shbg |
sex hormone binding globulin |
increases expression |
ISO |
2-hydroxyestradiol results in increased expression of SHBG mRNA; 2-hydroxyestradiol results in increased expression of SHBG protein |
CTD |
PMID:21793624 |
|
NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
Sult1a1 |
sulfotransferase family 1A member 1 |
affects sulfation increases sulfation |
ISO |
SULT1A1 gene polymorphism affects the sulfation of 2-hydroxyestradiol SULT1A1 protein results in increased sulfation of 2-hydroxyestradiol |
CTD |
PMID:16517757 |
|
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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G |
Sult1e1 |
sulfotransferase family 1E member 1 |
affects sulfation |
ISO |
2-hydroxyestradiol affects the sulfation of SULT1E1 protein |
CTD |
PMID:11358677 |
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NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases glucuronidation |
ISO |
UGT1A1 protein results in increased glucuronidation of 2-hydroxyestradiol |
CTD |
PMID:14871858 PMID:15117964 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
increases glucuronidation |
ISO |
UGT1A3 protein results in increased glucuronidation of 2-hydroxyestradiol |
CTD |
PMID:15117964 |
|
NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ckb |
creatine kinase B |
multiple interactions |
EXP |
2-hydroxyestrone inhibits the reaction [Estradiol results in increased expression of CKB] |
CTD |
PMID:10030690 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Esr1 |
estrogen receptor 1 |
affects binding multiple interactions |
ISO |
2-hydroxyestrone binds to ESR1 protein 2-hydroxyestrone binds to and results in increased activity of ESR1 protein |
CTD |
PMID:16728493 PMID:17713618 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
2-hydroxyestrone binds to and results in increased activity of ESR2 protein |
CTD |
PMID:17713618 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression |
ISO |
2-hydroxyestrone results in decreased expression of FSHB protein |
CTD |
PMID:6401747 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Lhb |
luteinizing hormone subunit beta |
decreases expression |
ISO |
2-hydroxyestrone results in decreased expression of LHB protein |
CTD |
PMID:6401747 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases glucuronidation |
ISO |
UGT1A1 protein results in increased glucuronidation of 2-hydroxyestrone |
CTD |
PMID:15117964 |
|
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
increases glucuronidation |
ISO |
UGT1A3 protein results in increased glucuronidation of 2-hydroxyestrone |
CTD |
PMID:15117964 |
|
NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
increases glucuronidation |
ISO |
UGT1A9 protein results in increased glucuronidation of 2-hydroxyestrone |
CTD |
PMID:15117964 |
|
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased activity of AKT1 protein]]; Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased activity of AKT1 protein] |
CTD |
PMID:26048653 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Ecdysterone results in increased expression of BAX protein |
CTD |
PMID:33878320 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
affects expression |
ISO |
Ecdysterone affects the expression of BCL2 protein |
CTD |
PMID:33878320 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
increases activity increases cleavage |
ISO |
Ecdysterone results in increased activity of CASP3 protein Ecdysterone results in increased cleavage of CASP3 protein |
CTD |
PMID:29126784 PMID:33878320 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]]; Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein] |
CTD |
PMID:26048653 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]]; Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]; Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein] |
CTD |
PMID:26048653 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression increases expression |
ISO |
Ecdysterone results in decreased expression of HSPA5 protein Ecdysterone results in increased expression of HSPA5 mRNA |
CTD |
PMID:29126784 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Mtor |
mechanistic target of rapamycin kinase |
affects expression |
ISO |
Ecdysterone affects the expression of MTOR protein |
CTD |
PMID:33878320 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases response to substance |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium affects the localization of NFE2L2 protein]]; Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium affects the localization of NFE2L2 protein] NFE2L2 results in increased susceptibility to Ecdysterone |
CTD |
PMID:26048653 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
Ecdysterone results in increased cleavage of PARP1 protein |
CTD |
PMID:33878320 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Sqstm1 |
sequestosome 1 |
affects expression |
ISO |
Ecdysterone affects the expression of SQSTM1 protein |
CTD |
PMID:33878320 |
|
NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
brassinolide results in decreased expression of BCL2 protein |
CTD |
PMID:17557751 PMID:20833159 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
brassinolide results in decreased expression of BCL2L1 protein |
CTD |
PMID:20833159 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bid |
BH3 interacting domain death agonist |
decreases expression |
ISO |
brassinolide results in decreased expression of BID protein |
CTD |
PMID:20833159 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Casp3 |
caspase 3 |
increases activity increases expression |
ISO |
brassinolide results in increased activity of CASP3 protein brassinolide results in increased expression of CASP3 protein modified form |
CTD |
PMID:17557751 PMID:20833159 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
ISO |
brassinolide results in decreased expression of CCNB1 protein |
CTD |
PMID:20833159 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
brassinolide results in decreased expression of CCND1 protein |
CTD |
PMID:20833159 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccne1 |
cyclin E1 |
decreases expression |
ISO |
brassinolide results in decreased expression of CCNE1 protein |
CTD |
PMID:20833159 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression |
ISO |
brassinolide results in decreased expression of CDK2 protein |
CTD |
PMID:20833159 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
brassinolide results in decreased expression of CDK4 protein |
CTD |
PMID:20833159 |
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NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
brassinolide results in increased expression of CDKN1A protein |
CTD |
PMID:20833159 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
ISO |
brassinolide results in decreased expression of CDKN1B protein |
CTD |
PMID:20833159 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Esr1 |
estrogen receptor 1 |
decreases expression |
ISO |
brassinolide results in decreased expression of ESR1 |
CTD |
PMID:20833159 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
affects localization decreases expression |
ISO |
brassinolide affects the localization of ESR2 protein brassinolide results in decreased expression of ESR2 |
CTD |
PMID:20833159 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
brassinolide results in decreased expression of MDM2 protein |
CTD |
PMID:20833159 |
|
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases expression |
ISO |
brassinolide results in decreased expression of RB1 protein; brassinolide results in decreased expression of RB1 protein modified form |
CTD |
PMID:20833159 |
|
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
brassinolide results in increased expression of TP53 protein |
CTD |
PMID:20833159 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Cdh5 |
cadherin 5 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein] |
CTD |
PMID:31404653 |
|
NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Etv2 |
ETS variant transcription factor 2 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
|
NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
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G |
Gata2 |
GATA binding protein 2 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
|
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
decreases expression |
ISO |
Digitonin results in decreased expression of HIF1A protein |
CTD |
PMID:34717917 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
|
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Spn |
sialophorin |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
|
NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
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G |
Casp3 |
caspase 3 |
decreases activity multiple interactions |
EXP |
ponasterone A results in decreased activity of CASP3 protein L-161982 inhibits the reaction [ponasterone A results in decreased activity of CASP3 protein] |
CTD |
PMID:16396944 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
affects expression |
ISO |
ponasterone A affects the expression of FHIT protein |
CTD |
PMID:17019711 |
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NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
EXP |
L-161982 inhibits the reaction [ponasterone A results in increased expression of PTGS2 protein] |
CTD |
PMID:16396944 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
increases expression |
ISO |
ponasterone A results in increased expression of UGT1A3 protein |
CTD |
PMID:17058234 |
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NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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