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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzofuran
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Accession:CHEBI:36790 term browser browse the term
Synonyms:related_synonym: Formula=C8H6O
 xref: DrugBank:DB04179



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1-benzofuran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm1 acyl-CoA synthetase medium-chain family member 1 affects expression
increases expression
ISO benzofuran affects the expression of ACSM1 mRNA
benzofuran results in increased expression of ACSM1 mRNA
CTD PMID:17114358 PMID:17311802 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP benzofuran binds to and results in increased activity of AHR protein CTD PMID:21431309 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ces1d carboxylesterase 1D affects expression
increases expression
ISO benzofuran affects the expression of CES1 mRNA
benzofuran results in increased expression of CES1 mRNA
CTD PMID:17114358 PMID:17311802 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO benzofuran analog results in decreased activity of CYP19A1 protein CTD PMID:15968818 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO benzofuran analog results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
affects expression
ISO benzofuran results in increased expression of EPHX1 mRNA
benzofuran affects the expression of EPHX1 mRNA
CTD PMID:17114358 PMID:17311802 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects expression ISO benzofuran affects the expression of GSTM1 mRNA CTD PMID:17114358 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects expression ISO benzofuran affects the expression of IKBKG mRNA CTD PMID:17114358 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 affects expression ISO benzofuran affects the expression of ITIH1 mRNA CTD PMID:17114358 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO benzofuran results in increased activity of NFE2L2 protein CTD PMID:30114225 PMID:30203046 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO benzofuran results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO benzofuran results in increased activity of NR1I3 protein CTD PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pls1 plastin 1 affects expression ISO benzofuran affects the expression of PLS1 mRNA CTD PMID:17114358 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
increases activity
ISO benzofuran results in increased expression of PPARA mRNA
benzofuran results in increased activity of PPARA protein
CTD PMID:25689681 PMID:30203046 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Snhg11 small nucleolar RNA host gene 11 affects expression ISO benzofuran affects the expression of SNHG11 mRNA CTD PMID:17114358 NCBI chr 3:147,031,411...147,037,809 JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases activity ISO benzofuran results in increased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A affects expression ISO benzofuran affects the expression of TTC39A mRNA CTD PMID:17114358 NCBI chr 5:124,165,102...124,204,973
Ensembl chr 5:124,151,760...124,204,973
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO benzofuran affects the expression of UGDH mRNA CTD PMID:17114358 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
licocoumarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A multiple interactions ISO licocoumarone binds to and results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO licocoumarone results in decreased expression of MET protein CTD PMID:31838052 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      molecular entity 19809
        mancude ring 8361
          organic mancude parent 8361
            mancude organic heterocyclic parent 8361
              mancude organic heterobicyclic parent 5411
                benzofuran 20
                  1-benzofuran + 20
                  2-benzofuran 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19809
      composite particle 19809
        hadron 19809
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19706
                    p-block element atom 19706
                      carbon group element atom 19628
                        carbon atom 19618
                          organic molecular entity 19618
                            organic molecule 19558
                              organic cyclic compound 19349
                                organic heterocyclic compound 18582
                                  organic heteropolycyclic compound 18059
                                    organic heterobicyclic compound 16869
                                      mancude organic heterobicyclic parent 5411
                                        benzofuran 20
                                          1-benzofuran + 20
                                          2-benzofuran 0
paths to the root