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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tetralins
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Accession:CHEBI:36786 term browser browse the term
Definition:Compounds containing a tetralin skeleton.
Synonyms:related_synonym: 1,2,3,4-tetrahydronaphthalenes

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(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 multiple interactions ISO 5-methoxy-1-methyl-2-(n-propylamino)tetralin binds to and results in decreased activity of DRD2 protein CTD PMID:10728880 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO 5-methoxy-1-methyl-2-(n-propylamino)tetralin binds to and results in decreased activity of DRD3 protein CTD PMID:10728880 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327 		JBrowse link
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Am 580 promotes the reaction [Tretinoin results in increased expression of ABCG2 mRNA] CTD PMID:20562004 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Ada adenosine deaminase increases expression ISO Am 580 results in increased expression of ADA mRNA CTD PMID:16982809 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Agpat4 1-acylglycerol-3-phosphate O-acyltransferase 4 increases expression ISO Am 580 results in increased expression of AGPAT4 mRNA CTD PMID:16982809 NCBI chr 1:48,716,094...48,826,292
Ensembl chr 1:48,719,633...48,825,364 		JBrowse link
G Agrn agrin decreases expression ISO Am 580 results in decreased expression of AGRN mRNA CTD PMID:16982809 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645 		JBrowse link
G Ajap1 adherens junctions associated protein 1 increases expression ISO Am 580 results in increased expression of AJAP1 mRNA CTD PMID:16982809 NCBI chr 5:170,615,885...170,679,315
Ensembl chr 5:170,615,886...170,679,315 		JBrowse link
G Aplp2 amyloid beta precursor like protein 2 increases expression ISO Am 580 results in increased expression of APLP2 mRNA CTD PMID:16982809 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839 		JBrowse link
G Ar androgen receptor decreases activity ISO Am 580 results in decreased activity of AR protein CTD PMID:25257666 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Am 580 results in decreased expression of ATP2B1 mRNA CTD PMID:16982809 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579 		JBrowse link
G Bag2 BAG cochaperone 2 increases expression ISO Am 580 results in increased expression of BAG2 mRNA CTD PMID:16982809 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118 		JBrowse link
G Calcrl calcitonin receptor like receptor decreases expression ISO Am 580 results in decreased expression of CALCRL mRNA CTD PMID:16982809 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232 		JBrowse link
G Capn1 calpain 1 decreases expression
decreases activity		 ISO Am 580 results in decreased expression of CAPN1 mRNA
Am 580 results in decreased activity of CAPN1 protein		 CTD PMID:17460283 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322 		JBrowse link
G Capn2 calpain 2 decreases expression
multiple interactions
decreases activity		 ISO Am 580 results in decreased expression of CAPN2 mRNA
Am 580 inhibits the reaction [Hydrogen Peroxide results in increased activity of CAPN2 protein]; Am 580 inhibits the reaction [Hydrogen Peroxide results in increased expression of CAPN2 mRNA]
Am 580 results in decreased activity of CAPN2 protein		 CTD PMID:17460283 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811 		JBrowse link
G Cd1d1 CD1d1 molecule increases expression
multiple interactions		 ISO Am 580 results in increased expression of CD1D mRNA
Ro 41-5253 inhibits the reaction [Am 580 results in increased expression of CD1D mRNA]		 CTD PMID:16982809 PMID:17392484 NCBI chr 2:186,330,298...186,333,805
Ensembl chr 2:186,330,298...186,333,805 		JBrowse link
G Cd300a Cd300a molecule increases expression ISO Am 580 results in increased expression of CD300A mRNA CTD PMID:16982809 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947 		JBrowse link
G Cd300lb CD300 molecule-like family member b increases expression ISO Am 580 results in increased expression of CD300LB mRNA CTD PMID:16982809 NCBI chr10:103,471,082...103,481,071
Ensembl chr10:103,467,725...103,481,153 		JBrowse link
G Cd300lf Cd300 molecule-like family member F increases expression ISO Am 580 results in increased expression of CD300LF mRNA CTD PMID:16982809 NCBI chr10:103,669,781...103,690,584
Ensembl chr10:103,670,028...103,687,425 		JBrowse link
G Cd38 CD38 molecule increases expression
multiple interactions		 ISO Am 580 results in increased expression of CD38 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Am 580 results in increased expression of CD38 protein]; [Ro 25-6603 co-treated with Am 580] results in increased expression of CD38 protein		 CTD PMID:16329108 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects localization ISO Am 580 affects the localization of CDKN1B protein CTD PMID:16618747 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdr2l cerebellar degeneration-related protein 2-like decreases expression ISO Am 580 results in decreased expression of CDR2L mRNA CTD PMID:16982809 NCBI chr10:103,934,364...103,948,318
Ensembl chr10:103,934,797...103,948,322 		JBrowse link
G Col5a3 collagen type V alpha 3 chain increases expression ISO Am 580 results in increased expression of COL5A3 mRNA CTD PMID:16982809 NCBI chr 8:21,786,324...21,831,751
Ensembl chr 8:21,786,324...21,831,668 		JBrowse link
G Cttnbp2 cortactin binding protein 2 decreases expression ISO Am 580 results in decreased expression of CTTNBP2 mRNA CTD PMID:16982809 NCBI chr 4:42,932,897...43,096,454
Ensembl chr 4:42,932,903...43,096,399 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO Am 580 results in increased expression of CYP19A1 mRNA CTD PMID:15941851 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO Ro 41-5253 inhibits the reaction [Am 580 results in increased expression of CYP26A1 mRNA] CTD PMID:10953040 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein increases expression ISO Am 580 results in increased expression of DCSTAMP mRNA CTD PMID:16982809 NCBI chr 7:78,642,016...78,651,763
Ensembl chr 7:78,649,875...78,650,906 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Am 580 results in increased expression of DHRS3 mRNA CTD PMID:16982809 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383 		JBrowse link
G Dmpk DM1 protein kinase decreases expression ISO Am 580 results in decreased expression of DMPK mRNA CTD PMID:16982809 NCBI chr 1:79,988,096...79,999,358
Ensembl chr 1:79,989,019...79,999,364 		JBrowse link
G Dmwd DM1 locus, WD repeat containing decreases expression ISO Am 580 results in decreased expression of DMWD mRNA CTD PMID:16982809 NCBI chr 1:79,981,270...79,987,997
Ensembl chr 1:79,981,355...79,987,562 		JBrowse link
G Dnajc5b DnaJ heat shock protein family (Hsp40) member C5 beta increases expression ISO Am 580 results in increased expression of DNAJC5B mRNA CTD PMID:16982809 NCBI chr 2:104,290,726...104,382,846
Ensembl chr 2:104,290,726...104,382,878 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Am 580 results in increased expression of ETS2 mRNA CTD PMID:16982809 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495 		JBrowse link
G Fam241a family with sequence similarity 241 member A decreases expression ISO Am 580 results in decreased expression of FAM241A mRNA CTD PMID:16982809 NCBI chr 2:232,214,331...232,245,319
Ensembl chr 2:232,214,331...232,245,319 		JBrowse link
G Fas Fas cell surface death receptor increases activity ISO Am 580 results in increased activity of FAS protein CTD PMID:15703382 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO Am 580 results in increased expression of FN1 mRNA CTD PMID:16982809 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fut7 fucosyltransferase 7 decreases expression ISO Am 580 results in decreased expression of FUT7 mRNA CTD PMID:16982809 NCBI chr 3:2,637,281...2,646,497
Ensembl chr 3:2,642,531...2,646,648 		JBrowse link
G Galm galactose mutarotase increases expression ISO Am 580 results in increased expression of GALM mRNA CTD PMID:18052213 NCBI chr 6:2,808,988...2,860,742
Ensembl chr 6:2,808,841...2,860,744 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Am 580 results in increased expression of GDF15 mRNA CTD PMID:16982809 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like decreases expression ISO Am 580 results in decreased expression of GPD1L mRNA CTD PMID:16982809 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191 		JBrowse link
G Gusb glucuronidase, beta increases expression ISO Am 580 results in increased expression of GUSB mRNA CTD PMID:16982809 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases expression ISO Am 580 results in increased expression of HIPK2 mRNA CTD PMID:16982809 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D decreases expression ISO Am 580 results in decreased expression of H2BC5 mRNA CTD PMID:16982809 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305 		JBrowse link
G Hlx H2.0-like homeobox decreases expression ISO Am 580 results in decreased expression of HLX mRNA CTD PMID:16982809 NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223 		JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions
increases expression		 ISO Ro 41-5253 inhibits the reaction [Am 580 results in increased expression of IFNGR1 protein] CTD PMID:16085646 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Am 580 results in decreased expression of IL1R1 mRNA CTD PMID:16982809 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein decreases expression ISO Am 580 results in decreased expression of IL1RAP mRNA CTD PMID:16982809 NCBI chr11:77,456,648...77,593,208
Ensembl chr11:77,463,954...77,593,207 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F increases expression ISO Am 580 results in increased expression of INPP5F mRNA CTD PMID:16982809 NCBI chr 1:200,037,749...200,116,524
Ensembl chr 1:200,037,749...200,116,524 		JBrowse link
G Ipcef1 interaction protein for cytohesin exchange factors 1 decreases expression ISO Am 580 results in decreased expression of IPCEF1 mRNA CTD PMID:16982809 NCBI chr 1:43,563,457...43,743,424
Ensembl chr 1:43,567,842...43,638,161 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions
increases expression
increases activity		 ISO Am 580 affects the localization of [Am 580 results in increased expression of IRF1 protein]; Ro 41-5253 inhibits the reaction [Am 580 results in increased expression of IRF1 protein]; Tretinoin promotes the reaction [Am 580 results in increased activity of IRF1 protein] CTD PMID:16085646 PMID:16636311 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531 		JBrowse link
G Itgae integrin subunit alpha E increases expression ISO Am 580 results in increased expression of ITGAE mRNA CTD PMID:16982809 NCBI chr10:59,652,324...59,711,885
Ensembl chr10:59,539,405...59,711,874 		JBrowse link
G Kifc2 kinesin family member C2 decreases expression ISO Am 580 results in decreased expression of KIFC2 mRNA CTD PMID:16982809 NCBI chr 7:117,722,732...117,730,702
Ensembl chr 7:117,723,263...117,730,702 		JBrowse link
G Lair1 leukocyte-associated immunoglobulin-like receptor 1 increases expression ISO Am 580 results in increased expression of LAIR1 mRNA CTD PMID:16982809 NCBI chr 1:73,752,192...73,870,421
Ensembl chr 1:73,837,944...73,868,695 		JBrowse link
G Lelp1 late cornified envelope-like proline-rich 1 decreases expression ISO Am 580 results in decreased expression of LELP1 mRNA CTD PMID:16982809 NCBI chr 2:192,035,927...192,037,885 JBrowse link
G LOC100302372 hypothetical protein LOC100302372 decreases expression ISO Am 580 results in decreased expression of KIAA0040 mRNA CTD PMID:16982809 NCBI chr13:77,784,516...77,822,333
Ensembl chr13:77,784,808...77,822,333 		JBrowse link
G LOC687399 hypothetical protein LOC687399 decreases expression ISO Am 580 results in decreased expression of C16ORF46 mRNA CTD PMID:16982809 NCBI chr19:49,508,321...49,518,721
Ensembl chr19:49,508,288...49,518,721 		JBrowse link
G Lrp11 LDL receptor related protein 11 decreases expression ISO Am 580 results in decreased expression of LRP11 mRNA CTD PMID:16982809 NCBI chr 1:1,702,696...1,731,210
Ensembl chr 1:1,702,696...1,731,210 		JBrowse link
G Man1c1 mannosidase, alpha, class 1C, member 1 decreases expression ISO Am 580 results in decreased expression of MAN1C1 mRNA CTD PMID:16982809 NCBI chr 5:152,775,031...152,920,130
Ensembl chr 5:152,774,855...152,920,343 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 decreases expression ISO Am 580 results in decreased expression of MAP3K6 mRNA CTD PMID:16982809 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 decreases expression ISO Am 580 results in decreased expression of MAP4K1 mRNA CTD PMID:16982809 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Am 580 co-treated with Retinoids] results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:15383624 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Am 580 co-treated with Retinoids] results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:15383624 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Metrn meteorin, glial cell differentiation regulator decreases expression ISO Am 580 results in decreased expression of METRN mRNA CTD PMID:16982809 NCBI chr10:15,164,439...15,166,457
Ensembl chr10:15,164,439...15,166,457 		JBrowse link
G Mgat4c MGAT4 family, member C decreases expression ISO Am 580 results in decreased expression of MGAT4C mRNA CTD PMID:16982809 NCBI chr 7:43,249,369...44,024,278
Ensembl chr 7:44,009,069...44,024,456 		JBrowse link
G Myorg myogenesis regulating glycosidase decreases expression ISO Am 580 results in decreased expression of MYORG mRNA CTD PMID:16982809 NCBI chr 5:57,873,404...57,882,008
Ensembl chr 5:57,876,498...57,881,944 		JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Am 580 results in decreased expression of NDRG2 mRNA CTD PMID:16982809 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin increases expression ISO Am580 increases expression of Nphs1 mRNA in podocytes RGD PMID:22125642 RGD:40902998 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
increases activity		 ISO Am 580 inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
Am 580 results in increased activity of NR1H4 protein		 CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO Am 580 results in increased expression of NRIP1 mRNA CTD PMID:16982809 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563 		JBrowse link
G Nrip3 nuclear receptor interacting protein 3 increases expression ISO Am 580 results in increased expression of NRIP3 mRNA CTD PMID:16982809 NCBI chr 1:174,385,424...174,411,141
Ensembl chr 1:174,385,424...174,411,141 		JBrowse link
G Nudt7 nudix hydrolase 7 decreases expression ISO Am 580 results in decreased expression of NUDT7 mRNA CTD PMID:16982809 NCBI chr19:46,455,745...46,470,070
Ensembl chr19:46,455,761...46,482,050 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 multiple interactions
increases expression		 ISO Ro 41-5253 inhibits the reaction [Am 580 results in increased expression of OAS2 mRNA] CTD PMID:16636311 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161 		JBrowse link
G Ocln occludin increases expression ISO Am 580 results in increased expression of OCLN mRNA CTD PMID:16982755 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Am 580 results in increased expression of OLR1 mRNA CTD PMID:16982809 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958 		JBrowse link
G Oma1 OMA1 zinc metallopeptidase increases expression ISO Am 580 results in increased expression of OMA1 mRNA CTD PMID:16982809 NCBI chr 5:122,847,624...122,900,475
Ensembl chr 5:122,847,645...122,900,475 		JBrowse link
G Pald1 phosphatase domain containing, paladin 1 decreases expression ISO Am 580 results in decreased expression of PALD1 mRNA CTD PMID:16982809 NCBI chr20:30,938,901...30,983,907
Ensembl chr20:30,938,901...30,975,472 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression ISO Am 580 results in increased expression of PAPSS2 mRNA CTD PMID:16982809 NCBI chr 1:251,145,264...251,230,716
Ensembl chr 1:251,145,253...251,230,715 		JBrowse link
G Pdlim2 PDZ and LIM domain 2 decreases expression ISO Am 580 results in decreased expression of PDLIM2 mRNA CTD PMID:16982809 NCBI chr15:51,843,562...51,856,785
Ensembl chr15:51,843,564...51,855,325 		JBrowse link
G Pdlim4 PDZ and LIM domain 4 decreases expression ISO Am 580 results in decreased expression of PDLIM4 mRNA CTD PMID:16982809 NCBI chr10:39,390,578...39,405,322
Ensembl chr10:39,390,581...39,405,311 		JBrowse link
G Pheta1 PH domain containing endocytic trafficking adaptor 1 decreases expression ISO Am 580 results in decreased expression of PHETA1 mRNA CTD PMID:16982809 NCBI chr12:40,225,316...40,230,573
Ensembl chr12:40,226,593...40,227,297 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 decreases expression ISO Am 580 results in decreased expression of PHLDA2 mRNA CTD PMID:16982809 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534 		JBrowse link
G Plbd1 phospholipase B domain containing 1 increases expression ISO Am 580 results in increased expression of PLBD1 mRNA CTD PMID:16982809 NCBI chr 4:170,564,387...170,620,681
Ensembl chr 4:170,564,367...170,620,703 		JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Am 580 results in increased expression of PLPP3 mRNA CTD PMID:16982809 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498 		JBrowse link
G Pon2 paraoxonase 2 decreases expression ISO Am 580 results in decreased expression of PON2 mRNA CTD PMID:16982809 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119 		JBrowse link
G Pram1 PML-RARA regulated adaptor molecule 1 increases expression ISO Am 580 results in increased expression of PRAM1 mRNA CTD PMID:16982809 NCBI chr 7:18,507,878...18,516,321
Ensembl chr 7:18,510,354...18,515,503 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase decreases expression ISO Am 580 results in decreased expression of QPRT mRNA CTD PMID:16982809 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568 		JBrowse link
G Rab15 RAB15, member RAS oncogene family decreases expression ISO Am 580 results in decreased expression of RAB15 mRNA CTD PMID:16982809 NCBI chr 6:99,845,952...99,870,320
Ensembl chr 6:99,845,954...99,870,024 		JBrowse link
G Rab20 RAB20, member RAS oncogene family increases expression ISO Am 580 results in increased expression of RAB20 mRNA CTD PMID:16982809 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326 		JBrowse link
G Rap1gap Rap1 GTPase-activating protein decreases expression ISO Am 580 results in decreased expression of RAP1GAP mRNA CTD PMID:16982809 NCBI chr 5:156,008,868...156,074,350
Ensembl chr 5:156,026,911...156,074,395 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression
decreases expression
multiple interactions		 ISO Am 580 results in increased expression of RARA protein
Am 580 results in decreased expression of RARA protein
2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; Am 580 binds to and results in increased activity of RARA protein; Am 580 inhibits the reaction [Ro 41-5253 results in decreased activity of RARA protein]		 CTD PMID:10779427 PMID:16178010 PMID:16636311 PMID:17290005 PMID:30076181 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO [Am 580 co-treated with Retinoids] results in decreased phosphorylation of RB1 protein CTD PMID:15383624 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342 		JBrowse link
G Rbp1 retinol binding protein 1 increases expression ISO Am 580 results in increased expression of RBP1 mRNA CTD PMID:16982809 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842 		JBrowse link
G Reps2 RALBP1 associated Eps domain containing 2 decreases expression ISO Am 580 results in decreased expression of REPS2 mRNA CTD PMID:16982809 NCBI chr  X:33,786,611...34,062,941
Ensembl chr  X:33,884,499...34,057,399 		JBrowse link
G Rflnb refilin B increases expression ISO Am 580 results in increased expression of RFLNB mRNA CTD PMID:16982809 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380 		JBrowse link
G Rfxap regulatory factor X-associated protein decreases expression ISO Am 580 results in decreased expression of RFXAP mRNA CTD PMID:16982809 NCBI chr 2:144,003,453...144,007,636
Ensembl chr 2:144,003,454...144,007,636 		JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 increases expression ISO Am 580 results in increased expression of RHOBTB3 mRNA CTD PMID:16982809 NCBI chr 2:2,627,655...2,683,305
Ensembl chr 2:2,627,393...2,683,116 		JBrowse link
G Rxra retinoid X receptor alpha increases activity ISO Am 580 results in increased activity of RXRA protein CTD PMID:21543282 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Sel1l3 SEL1L family member 3 increases expression ISO Am 580 results in increased expression of SEL1L3 mRNA CTD PMID:16982809 NCBI chr14:60,122,968...60,229,565
Ensembl chr14:60,123,169...60,229,734 		JBrowse link
G Selplg selectin P ligand decreases expression ISO Am 580 results in decreased expression of SELPLG mRNA CTD PMID:16982809 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196 		JBrowse link
G Slc26a11 solute carrier family 26 member 11 increases expression ISO Am 580 results in increased expression of SLC26A11 mRNA CTD PMID:16982809 NCBI chr10:108,479,105...108,504,188
Ensembl chr10:108,480,368...108,503,706 		JBrowse link
G Slitrk4 SLIT and NTRK-like family, member 4 increases expression ISO Am 580 results in increased expression of SLITRK4 mRNA CTD PMID:16982809 NCBI chr  X:147,582,195...147,589,529 JBrowse link
G Snai3 snail family transcriptional repressor 3 increases expression ISO Am 580 results in increased expression of SNAI3 mRNA CTD PMID:16982809 NCBI chr19:55,276,211...55,290,031
Ensembl chr19:55,277,549...55,284,663 		JBrowse link
G Ssmem1 serine-rich single-pass membrane protein 1 decreases expression ISO Am 580 results in decreased expression of SSMEM1 mRNA CTD PMID:16982809 NCBI chr 4:57,823,411...57,833,706
Ensembl chr 4:57,823,411...57,834,115 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Am 580 results in increased phosphorylation of and results in increased activity of STAT1 protein; Ro 41-5253 inhibits the reaction [Am 580 results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:16085646 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Sts steroid sulfatase increases activity ISO Am 580 results in increased activity of STS protein CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750 		JBrowse link
G Synpo synaptopodin increases expression ISO AM580 increases expression of Synpo mRNA in podocytes RGD PMID:22125642 RGD:40902998 NCBI chr18:55,863,081...55,921,412
Ensembl chr18:55,865,467...55,916,220 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 decreases expression ISO Am 580 results in decreased expression of TACSTD2 mRNA CTD PMID:16982809 NCBI chr 4:98,341,187...98,342,887
Ensembl chr 4:98,341,188...98,342,887 		JBrowse link
G Tbc1d2 TBC1 domain family, member 2 increases expression ISO Am 580 results in increased expression of TBC1D2 mRNA CTD PMID:16982809 NCBI chr 5:62,213,001...62,261,467
Ensembl chr 5:62,212,982...62,260,105 		JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked decreases expression ISO Am 580 results in decreased expression of TBL1X mRNA CTD PMID:16982809 NCBI chr  X:44,959,883...44,988,551
Ensembl chr  X:44,830,849...44,988,551 		JBrowse link
G Tbl2 transducin (beta)-like 2 increases expression ISO Am 580 results in increased expression of TBL2 mRNA CTD PMID:16982809 NCBI chr12:24,565,843...24,578,855
Ensembl chr12:24,565,849...24,578,786 		JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO [Am 580 co-treated with Retinoids] results in decreased expression of TERT mRNA CTD PMID:16482212 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions
increases activity
increases expression		 ISO [Am 580 co-treated with CD 2425] results in increased activity of TGM2 protein
Am 580 results in increased activity of TGM2 protein
Am 580 results in increased expression of TGM2 mRNA		 CTD PMID:2884032 PMID:9516142 PMID:16982809 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257 		JBrowse link
G Thbs3 thrombospondin 3 increases expression ISO Am 580 results in increased expression of THBS3 mRNA CTD PMID:16982809 NCBI chr 2:188,528,979...188,540,738
Ensembl chr 2:188,528,979...188,540,736 		JBrowse link
G Tmem14a transmembrane protein 14A decreases expression ISO Am 580 results in decreased expression of TMEM14A mRNA CTD PMID:16982809 NCBI chr 9:27,333,956...27,345,612
NCBI chr 9:27,334,103...27,351,302
Ensembl chr 9:27,343,853...27,345,070
Ensembl chr 9:27,343,853...27,345,070 		JBrowse link
G Tnf tumor necrosis factor increases activity ISO Am 580 results in increased activity of TNF protein CTD PMID:15703382 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases activity ISO Am 580 results in increased activity of TNFSF10 protein CTD PMID:15703382 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899 		JBrowse link
G Tnfsf12 TNF superfamily member 12 decreases expression ISO Am 580 results in decreased expression of TNFSF12 mRNA CTD PMID:16982809 NCBI chr10:56,290,780...56,300,137
Ensembl chr10:56,290,780...56,300,077 		JBrowse link
G Tns1 tensin 1 decreases expression ISO Am 580 results in decreased expression of TNS1 mRNA CTD PMID:16982809 NCBI chr 9:81,190,192...81,401,020
Ensembl chr 9:81,194,119...81,400,987 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B decreases expression ISO Am 580 results in decreased expression of ZBTB7B mRNA CTD PMID:16982809 NCBI chr 2:188,704,989...188,719,674
Ensembl chr 2:188,704,687...188,718,704 		JBrowse link
5,6,7,8-tetrahydro-2-naphthol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrrg estrogen-related receptor gamma multiple interactions ISO 5,6,7,8-tetrahydro-2-naphthol binds to and results in increased activity of ESRRG protein; 5,6,7,8-tetrahydro-2-naphthol inhibits the reaction [afimoxifene binds to and results in decreased activity of ESRRG protein] CTD PMID:31127318 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 5,6,7,8-tetrahydro-2-naphthol results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277 		JBrowse link
5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions ISO Nadolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP] CTD PMID:15060759 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [Nadolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP CTD PMID:17925438 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Nadolol co-treated with Mifepristone] promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]] CTD PMID:16321413 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:16321413 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Nadolol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655 		JBrowse link
6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO LG100268 increases expression of abca1 protein in mouse hippocampus RGD PMID:25217640 RGD:21408550 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
8-OH-DPAT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] CTD PMID:16545797 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions
increases expression		 ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein] CTD PMID:30366073 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of ARC mRNA] CTD PMID:19695244 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of BAX protein]		 CTD PMID:30366073 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2 protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2 protein] CTD PMID:30366073 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions		 ISO 8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in decreased expression of BCL2L1 protein]		 CTD PMID:30366073 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 ISO 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased cleavage of CASP3 protein]		 CTD PMID:30366073 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [CRH protein results in increased secretion of Serotonin] CTD PMID:14575894 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO		 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Levodopa results in increased expression of FOS protein]
8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]		 CTD PMID:18585397 PMID:19115412 PMID:19695244 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOSB mRNA] CTD PMID:19695244 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein] CTD PMID:23692952 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A affects binding
increases expression
multiple interactions
increases activity		 ISO
EXP		 8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein
8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA; 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein
4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine]; 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]; 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and affects the activity of HTR1A protein; 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Morphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in increased susceptibility to Serotonin; [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] which results in decreased susceptibility to Pilocarpine; Cocaine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]; Diazinon promotes the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]; Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form]; Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form]; Fluoxetine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein]; Parathion inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]; Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine]
8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide analog inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein]
8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]; 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]; methamidophos inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]; NCF1 protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; NCF1 protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]; PRKCD protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; PRKCD protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]		 CTD PMID:2533336 PMID:8539317 PMID:9723786 PMID:9809859 PMID:10640309 PMID:10665824 PMID:11927170 PMID:12591222 PMID:14767715 PMID:15482641 PMID:15798786 PMID:15893579 PMID:16528294 PMID:17035140 PMID:17300168 PMID:18622176 PMID:19211973 PMID:20580787 PMID:21520940 PMID:21871486 PMID:22265196 PMID:30366073 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR7 protein CTD PMID:15802305 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression		 ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IFNG protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IFNG protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IFNG protein] CTD PMID:30366073 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15802305 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein]		 CTD PMID:15802305 PMID:23692952 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IL6 protein
acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IL6 protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IL6 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of IL6 protein]		 CTD PMID:15802305 PMID:30366073 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA] CTD PMID:19695244 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]; 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]; 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased phosphorylation of and affects the localization of NCF1 protein; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased phosphorylation of and affects the localization of NCF1 protein]; NCF1 protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; NCF1 protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]; PRKCD protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased phosphorylation of and affects the localization of NCF1 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to HTR1A protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased phosphorylation of and affects the localization of NCF1 protein] CTD PMID:30366073 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA] CTD PMID:19695244 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions EXP [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form; Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of OXT protein modified form] CTD PMID:22265196 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534 		JBrowse link
G Pdyn prodynorphin multiple interactions EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Levodopa results in increased expression of PDYN mRNA] CTD PMID:19115412 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form; Estradiol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in decreased activity of HTR1A protein] which results in increased expression of POMC protein modified form] CTD PMID:22265196 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]; 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]; 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of and results in increased phosphorylation of PRKCD protein; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]]; PRKCD protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A mRNA]; PRKCD protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of HTR1A protein]; PRKCD protein affects the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased phosphorylation of and affects the localization of NCF1 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [NCF1 protein binds to PRKCD protein]]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [PRKCD protein binds to HTR1A protein]] CTD PMID:30366073 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 ISO acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of PTGS2 protein]; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of PTGS2 protein]; rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of PTGS2 protein] CTD PMID:30366073 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 increases response to substance EXP SLC6A4 results in increased susceptibility to 8-Hydroxy-2-(di-n-propylamino)tetralin CTD PMID:18581099 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:15802305 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
Ethylketocyclazocine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprk1 opioid receptor, kappa 1 multiple interactions
affects binding		 EXP Cadmium inhibits the reaction [Ethylketocyclazocine binds to OPRK1 protein]; Copper inhibits the reaction [Ethylketocyclazocine binds to OPRK1 protein]; Mercury inhibits the reaction [Ethylketocyclazocine binds to OPRK1 protein] CTD PMID:2162496 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305 		JBrowse link
lasofoxifene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor increases expression EXP Lasofoxifene results in increased expression of AR protein CTD PMID:16837883 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Areg amphiregulin multiple interactions
increases expression		 ISO Lasofoxifene inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA]
Lasofoxifene results in increased expression of AREG mRNA		 CTD PMID:19022889 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Defb1 defensin beta 1 multiple interactions ISO [Progesterone co-treated with Lasofoxifene] results in increased expression of DEFB1 mRNA CTD PMID:18367319 NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176 		JBrowse link
G Esr2 estrogen receptor 2 increases expression EXP Lasofoxifene results in increased expression of ESR2 protein CTD PMID:16837883 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression
multiple interactions		 ISO Lasofoxifene results in increased expression of IDO1 mRNA
Lasofoxifene inhibits the reaction [Estradiol results in increased expression of IDO1 mRNA]		 CTD PMID:18367319 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity EXP Lasofoxifene results in increased activity of MMP2 protein CTD PMID:15576828 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G P2ry14 purinergic receptor P2Y14 multiple interactions ISO Lasofoxifene inhibits the reaction [Estradiol results in increased expression of P2RY14 mRNA] CTD PMID:18367319 NCBI chr 2:149,331,948...149,379,336
Ensembl chr 2:149,331,948...149,347,796 		JBrowse link
G Pgr progesterone receptor increases expression EXP Lasofoxifene results in increased expression of PGR protein CTD PMID:16837883 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 multiple interactions ISO [Progesterone co-treated with Lasofoxifene] results in increased expression of SPINK1 mRNA CTD PMID:18367319 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119 		JBrowse link
levobunolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-DMb RT1 class II, locus DMb affects expression ISO Levobunolol affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290 		JBrowse link
Liranaftate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO liranaftate results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Tslp thymic stromal lymphopoietin decreases expression
decreases expression 		ISO Liranaftate decreases expression of TSLP mRNA in epidermal keratinocytes
Liranaftate decreases expression of Tslp mRNA in ear skin		 RGD PMID:30187507, PMID:30187507 RGD:38596345, RGD:38596345 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361 		JBrowse link
Mibefradil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Mibefradil results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946 		JBrowse link
G Agt angiotensinogen multiple interactions ISO Mibefradil inhibits the reaction [AGT protein results in increased abundance of Aldosterone]; Mibefradil inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium] CTD PMID:18331727 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G affects response to substance
multiple interactions		 ISO
EXP		 CACNA1G protein affects the susceptibility to Mibefradil
Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1G protein]		 CTD PMID:12130671 PMID:17110049 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions EXP
ISO		 Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1H protein]
Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]		 CTD PMID:9930755 PMID:17110049 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I multiple interactions EXP Mibefradil inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CACNA1I protein] CTD PMID:17110049 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Mibefradil inhibits the reaction [Potassium results in increased secretion of CALCA protein] CTD PMID:18178321 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO Mibefradil inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA] CTD PMID:18331727 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity ISO Mibefradil results in decreased activity of CYP3A4 protein CTD PMID:15860655 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Mibefradil inhibits the reaction [[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA] CTD PMID:8934362 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Hexa hexosaminidase subunit alpha multiple interactions EXP Mibefradil inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of [HEXB protein binds to HEXA protein]] CTD PMID:19546254 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773 		JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP Mibefradil inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of [HEXB protein binds to HEXA protein]] CTD PMID:19546254 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Mibefradil inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Mibefradil results in decreased activity of KCNH2 protein		 CTD PMID:21158687 PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP Mibefradil inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of LAMP1 protein] CTD PMID:19546254 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419 		JBrowse link
rotigotine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO rotigotine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
sertraline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO Sertraline results in increased activity of ABCB1 protein CTD PMID:23273999 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Sertraline inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17728140 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Alb albumin affects binding ISO Sertraline binds to ALB protein CTD PMID:26471709 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Sertraline results in increased expression of ASAH1 mRNA CTD PMID:15342952 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Sertraline results in increased expression of ASNS mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163 		JBrowse link
G Atf2 activating transcription factor 2 increases expression ISO Sertraline results in increased expression of ATF2 mRNA CTD PMID:24865413 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Sertraline results in increased expression of ATF4 protein CTD PMID:24865413 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
decreases expression		 ISO Sertraline affects the expression of BCL2 protein
Sertraline results in decreased expression of BCL2 protein		 CTD PMID:18403212 PMID:24194395 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Sertraline results in increased expression of BDNF protein CTD PMID:18403212 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO 4-phenylbutyric acid inhibits the reaction [Sertraline results in increased activity of CASP3 protein]; Sertraline results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:24194395 PMID:24865413 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp4 caspase 4 increases cleavage
multiple interactions		 ISO Sertraline results in increased cleavage of CASP4 protein
MAP4K4 mutant form inhibits the reaction [Sertraline results in increased cleavage of CASP4 protein]		 CTD PMID:24865413 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity		 ISO 4-phenylbutyric acid inhibits the reaction [Sertraline results in increased activity of CASP7 protein] CTD PMID:24865413 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Sertraline results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:24194395 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase multiple interactions EXP Nitric Oxide promotes the reaction [Sertraline inhibits the reaction [3-nitropropionic acid results in decreased activity of CAT protein]]; Sertraline inhibits the reaction [3-nitropropionic acid results in decreased activity of CAT protein] CTD PMID:20305041 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cd14 CD14 molecule decreases expression ISO Sertraline results in decreased expression of CD14 mRNA CTD PMID:24865413 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP Sertraline results in increased expression of CREB1 mRNA CTD PMID:8601816 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Cryaa crystallin, alpha A increases expression ISO Sertraline results in increased expression of CRYAA mRNA CTD PMID:24865413 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187 		JBrowse link
G Cul1 cullin 1 decreases expression ISO Sertraline results in decreased expression of CUL1 mRNA CTD PMID:24865413 NCBI chr 4:77,211,814...77,283,369
Ensembl chr 4:77,211,692...77,280,250 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP Sertraline results in decreased expression of CYP11A1 mRNA CTD PMID:29850907 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Sertraline results in decreased expression of CYP17A1 mRNA CTD PMID:29850907 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Sertraline results in decreased activity of CYP19A1 protein CTD PMID:26162595 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 decreases expression EXP Sertraline results in decreased expression of CYP21A1 mRNA CTD PMID:29850907 NCBI chr20:4,486,213...4,489,358
Ensembl chr20:4,486,219...4,489,550 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases activity		 ISO [Sertraline results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion; CYP2B6 protein results in decreased methylation of and results in increased metabolism of Sertraline CTD PMID:15547048 PMID:26599973 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 affects metabolic processing
increases metabolic processing
decreases methylation
multiple interactions		 ISO CYP2C19 gene polymorphism affects the metabolism of Sertraline
CYP2C19 protein results in increased metabolism of Sertraline
CYP2C19 protein results in decreased methylation of Sertraline
CYP2C19 protein results in decreased amination of and results in increased metabolism of Sertraline; CYP2C19 protein results in decreased methylation of and results in increased metabolism of Sertraline		 CTD PMID:11452243 PMID:15547048 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO CYP2D6 protein results in decreased methylation of and results in increased metabolism of Sertraline CTD PMID:15547048 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO CYP3A4 protein results in decreased amination of and results in increased metabolism of Sertraline; CYP3A4 protein results in decreased methylation of and results in increased metabolism of Sertraline; Sertraline promotes the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin] CTD PMID:15547048 PMID:19299527 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance ISO DBH protein results in increased susceptibility to Sertraline CTD PMID:15148402 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO 4-phenylbutyric acid inhibits the reaction [Sertraline results in increased expression of DDIT3 protein]; MAP4K4 mutant form inhibits the reaction [Sertraline results in increased expression of DDIT3 protein]
Sertraline results in increased expression of DDIT3 mRNA; Sertraline results in increased expression of DDIT3 protein		 CTD PMID:24865413 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Sertraline results in increased expression of DEPP1 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562 		JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Sertraline results in increased expression of DNAJC5 mRNA; Sertraline results in increased expression of DNAJC5 protein CTD PMID:11257428 NCBI chr 3:177,012,714...177,047,787
Ensembl chr 3:177,013,604...177,043,902 		JBrowse link
G Drd1 dopamine receptor D1 increases expression EXP Sertraline results in increased expression of DRD1 mRNA CTD PMID:16499906 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Sertraline results in increased expression of DUSP1 mRNA CTD PMID:24865413 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Sertraline results in increased expression of DUSP10 mRNA CTD PMID:24865413 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455 		JBrowse link
G Dusp14 dual specificity phosphatase 14 increases expression ISO Sertraline results in increased expression of DUSP14 mRNA CTD PMID:24865413 NCBI chr10:71,363,688...71,383,602
Ensembl chr10:71,363,688...71,383,602 		JBrowse link
G Dusp16 dual specificity phosphatase 16 increases expression ISO Sertraline results in increased expression of DUSP16 mRNA CTD PMID:24865413 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177 		JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO Sertraline results in increased expression of DUSP8 mRNA CTD PMID:24865413 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460 		JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO Sertraline results in increased expression of EGFR mRNA CTD PMID:24865413 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases expression		 ISO MAP4K4 mutant form inhibits the reaction [Sertraline results in increased phosphorylation of EIF2AK3 protein]; Sertraline results in increased expression of and results in increased phosphorylation of EIF2AK3 protein
Sertraline results in increased expression of EIF2AK3 mRNA		 CTD PMID:24865413 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Sertraline results in increased phosphorylation of EIF2S1 protein CTD PMID:24865413 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Sertraline results in increased expression of ERN1 mRNA CTD PMID:24865413 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Sertraline results in increased expression of FABP1 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Sertraline results in increased expression of FNDC4 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 6:26,387,284...26,389,524 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression		 EXP
ISO		 Sertraline results in decreased expression of FOS mRNA
Sertraline results in increased expression of FOS mRNA		 CTD PMID:7612155 PMID:24865413 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Sertraline results in increased expression of GADD45A mRNA CTD PMID:24865413 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Sertraline results in increased expression of GADD45B mRNA CTD PMID:24865413 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Sertraline results in increased expression of GDPD3 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Sertraline results in increased expression of HERPUD1 mRNA CTD PMID:24865413 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254 		JBrowse link
G Hpn hepsin increases expression ISO Sertraline results in increased expression of HPN mRNA CTD PMID:15342952 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP Sertraline results in decreased expression of HSD3B1 mRNA CTD PMID:29850907
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Sertraline results in increased expression of HSPA1A mRNA CTD PMID:24865413 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Sertraline results in increased expression of HSPA1B mRNA CTD PMID:24865413 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression
decreases expression		 EXP
ISO		 Sertraline results in increased expression of HSPA8 mRNA alternative form; Sertraline results in increased expression of HSPA8 protein alternative form
Sertraline results in decreased expression of HSPA8 mRNA		 CTD PMID:10425221 PMID:24865413 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions
increases expression		 EXP [Estradiol co-treated with Sertraline] affects the expression of HTR1A mRNA
Sertraline results in increased expression of HTR1A mRNA		 CTD PMID:18650020 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
increases expression		 EXP [Estradiol co-treated with Sertraline] affects the expression of HTR2A mRNA; Estradiol promotes the reaction [Sertraline results in increased expression of HTR2A mRNA] CTD PMID:18650020 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
increases expression		 EXP [Estradiol co-treated with Sertraline] affects the expression of HTR2C mRNA; Estradiol promotes the reaction [Sertraline results in increased expression of HTR2C mRNA] CTD PMID:18650020 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Sertraline results in increased expression of INHBE mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169 		JBrowse link
G Ins2 insulin 2 multiple interactions EXP Sertraline affects the reaction [INS protein affects the phosphorylation of IRS1 protein]; Sertraline inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17728140 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases activity		 EXP Sertraline affects the reaction [INS protein affects the phosphorylation of IRS1 protein]
Sertraline results in decreased activity of IRS1 protein		 CTD PMID:17728140 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO Sertraline results in increased expression of and results in increased phosphorylation of JUN protein
Sertraline results in increased expression of JUN mRNA		 CTD PMID:24194395 PMID:24865413 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Sertraline results in increased expression of JUND mRNA CTD PMID:24865413 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Sertraline results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Sertraline inhibits the reaction [Ethanol results in increased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]]; Sertraline results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Sertraline results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 3:41,019,898...41,181,070
Ensembl chr 3:41,019,898...41,181,070 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions ISO Sertraline results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO Sertraline inhibits the reaction [Ethanol results in increased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]]; Sertraline results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr11:35,011,007...35,262,362
Ensembl chr11:35,024,196...35,099,383 		JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP Sertraline results in increased expression of LHB protein CTD PMID:29850907 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724 		JBrowse link
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B increases expression ISO Sertraline results in increased expression of SERPINA3 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540 		JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO Sertraline results in increased expression of HSPA6 mRNA CTD PMID:24865413 NCBI chr13:89,408,703...89,411,500 JBrowse link
G Lss lanosterol synthase increases expression ISO Sertraline results in increased expression of LSS mRNA CTD PMID:15342952 PMID:17567588 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497 		JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO MAOA protein results in decreased amination of and results in increased metabolism of Sertraline CTD PMID:15547048 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722 		JBrowse link
G Maob monoamine oxidase B multiple interactions ISO MAOB protein results in decreased amination of and results in increased metabolism of Sertraline CTD PMID:15547048 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 increases expression ISO Sertraline results in increased expression of MAP3K13 mRNA CTD PMID:24865413 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO Sertraline results in increased expression of MAP3K8 mRNA CTD PMID:24865413 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 multiple interactions
decreases expression		 ISO MAP4K4 mutant form inhibits the reaction [Sertraline results in increased cleavage of CASP4 protein]; MAP4K4 mutant form inhibits the reaction [Sertraline results in increased expression of DDIT3 protein]; MAP4K4 mutant form inhibits the reaction [Sertraline results in increased phosphorylation of EIF2AK3 protein]
Sertraline results in decreased expression of MAP4K4 mRNA		 CTD PMID:24865413 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Sertraline results in increased phosphorylation of and results in increased activity of MAPK1 protein
Sertraline results in increased phosphorylation of MAPK1 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Sertraline results in increased phosphorylation of MAPK1 protein]		 CTD PMID:17728140 PMID:24194395 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Sertraline results in increased phosphorylation of and results in increased activity of MAPK3 protein
Sertraline results in increased phosphorylation of MAPK3 protein		 CTD PMID:17728140 PMID:24194395 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP pyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17728140 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression ISO Sertraline results in increased expression of MAPK8IP3 mRNA CTD PMID:24865413 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Sertraline results in decreased expression of MCL1 protein CTD PMID:24194395 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Sertraline results in increased expression of MYC mRNA CTD PMID:24865413 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Sertraline results in increased expression of NFE2L2 mRNA CTD PMID:24865413 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Sertraline results in increased expression of NFKB1 mRNA CTD PMID:24865413 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression ISO Sertraline results in increased expression of NFKB2 mRNA CTD PMID:24865413 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Sertraline results in increased expression of NR0B2 mRNA CTD PMID:15342952 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Sertraline results in increased expression of NUPR1 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 decreases expression ISO Sertraline results in decreased expression of PECAM1 protein CTD PMID:15932816 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pf4 platelet factor 4 decreases expression ISO Sertraline results in decreased expression of PF4 protein CTD PMID:15932816 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258 		JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase increases expression ISO Sertraline results in increased expression of PHYH mRNA CTD PMID:15342952 NCBI chr17:77,287,580...77,304,482
Ensembl chr17:77,287,188...77,304,530 		JBrowse link
G Ppbp pro-platelet basic protein decreases expression ISO Sertraline results in decreased expression of PPBP protein CTD PMID:12912814 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Sertraline results in increased expression of PPP1R15A mRNA CTD PMID:24865413 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Sertraline results in decreased expression of PTGS2 mRNA; Sertraline results in decreased expression of PTGS2 protein CTD PMID:17499975 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rbx1 ring-box 1 decreases expression ISO Sertraline results in decreased expression of RBX1 mRNA CTD PMID:24865413 NCBI chr 7:122,700,849...122,710,907
Ensembl chr 7:122,700,854...122,709,935 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Sertraline results in increased expression of RELB mRNA CTD PMID:24865413 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825 		JBrowse link
G Rnf103 ring finger protein 103 increases expression EXP Sertraline results in increased expression of RNF103 mRNA CTD PMID:11071867 NCBI chr 4:99,398,479...99,415,193
Ensembl chr 4:99,398,494...99,421,164 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 decreases expression ISO Sertraline results in decreased expression of RPS6KA3 mRNA CTD PMID:24865413 NCBI chr  X:37,469,736...37,576,055
Ensembl chr  X:37,469,937...37,575,624 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP Sertraline results in increased phosphorylation of and results in increased activity of RPS6KB1 protein; Sirolimus inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:17728140 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364 		JBrowse link
G Sec61g SEC61 translocon subunit gamma decreases expression ISO Sertraline results in decreased expression of SEC61G mRNA CTD PMID:24865413 NCBI chr14:99,774,589...99,780,964
Ensembl chr14:99,774,589...99,780,964 		JBrowse link
G Sele selectin E decreases expression ISO Sertraline results in decreased expression of SELE protein CTD PMID:12912814 PMID:15932816 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341 		JBrowse link
G Selenos selenoprotein S increases expression ISO Sertraline results in increased expression of SELS mRNA CTD PMID:24865413 NCBI chr 1:126,979,579...126,989,344
Ensembl chr 1:126,979,575...126,989,344 		JBrowse link
G Selp selectin P decreases expression ISO Sertraline results in decreased expression of SELP protein CTD PMID:12912814 PMID:15932816 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Serpini1 serpin family I member 1 increases expression EXP Sertraline results in increased expression of SERPINI1 mRNA CTD PMID:16637596 NCBI chr 2:174,013,058...174,111,693
Ensembl chr 2:174,013,288...174,111,752 		JBrowse link
G Skp1 S-phase kinase-associated protein 1 decreases expression ISO Sertraline results in decreased expression of SKP1 mRNA CTD PMID:24865413 NCBI chr10:37,594,578...37,609,498
Ensembl chr10:37,594,578...37,609,498 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Sertraline results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression
decreases expression
affects response to substance
increases response to substance		 ISO
EXP		 Sertraline inhibits the reaction [Monocrotaline results in increased expression of SLC6A4 mRNA]
Sertraline results in increased expression of SLC6A4 mRNA
Sertraline results in decreased expression of SLC6A4 protein
SLC6A4 protein affects the susceptibility to Sertraline
[Estradiol co-treated with Sertraline] affects the expression of SLC6A4 mRNA; [Sertraline results in decreased expression of SLC6A4 protein] which results in decreased metabolism of Serotonin Uptake Inhibitors; Estradiol promotes the reaction [Sertraline results in increased expression of SLC6A4 mRNA]
SLC6A4 promoter polymorphism results in increased susceptibility to Sertraline		 CTD PMID:12151556 PMID:12955294 PMID:17042913 PMID:18650020 PMID:18923402 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463 		JBrowse link
G Ssr2 signal sequence receptor subunit 2 increases expression ISO Sertraline results in increased expression of SSR2 mRNA CTD PMID:24865413 NCBI chr 2:187,951,316...187,960,067
Ensembl chr 2:187,951,344...187,960,063 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Sertraline results in decreased expression of STAR mRNA CTD PMID:29850907 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression ISO Sertraline results in decreased expression of STAT3 mRNA; Sertraline results in decreased expression of STAT3 protein CTD PMID:17499975 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Stmn1 stathmin 1 decreases expression ISO Sertraline results in decreased expression of STMN1 mRNA CTD PMID:24865413 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806 		JBrowse link
G Syvn1 synoviolin 1 increases expression ISO Sertraline results in increased expression of SYVN1 mRNA CTD PMID:24865413 NCBI chr 1:221,409,281...221,416,229
Ensembl chr 1:221,409,271...221,417,886 		JBrowse link
G Tagln transgelin decreases expression ISO Sertraline results in decreased expression of TAGLN mRNA CTD PMID:15342952 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357 		JBrowse link
G Taok2 TAO kinase 2 increases expression ISO Sertraline results in increased expression of TAOK2 mRNA CTD PMID:24865413 NCBI chr 1:198,301,789...198,354,601
Ensembl chr 1:198,301,938...198,320,075 		JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO Sertraline results in increased expression of TFAP2A protein CTD PMID:28844482 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression		 ISO Sertraline results in decreased secretion of TNF protein
Sertraline results in increased expression of TNF mRNA		 CTD PMID:17499975 PMID:24194395 PMID:24865413 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tph2 tryptophan hydroxylase 2 multiple interactions
increases expression
increases activity		 EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Sertraline results in increased expression of TPH2 mRNA]
Sertraline results in increased expression of TPH2 mRNA; Sertraline results in increased expression of TPH2 protein
Sertraline results in increased activity of TPH2 protein		 CTD PMID:11901216 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061 		JBrowse link
G Txndc5 thioredoxin domain containing 5 decreases expression ISO Sertraline results in decreased expression of TXNDC5 mRNA CTD PMID:24865413 NCBI chr17:26,925,828...26,953,981
Ensembl chr17:26,925,828...26,953,970 		JBrowse link
G Ube2d4 ubiquitin-conjugating enzyme E2D 4 (putative) decreases expression ISO Sertraline results in decreased expression of UBE2D4 mRNA CTD PMID:24865413 NCBI chr14:2,933,097...2,934,571
Ensembl chr14:2,933,100...2,934,571 		JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 decreases expression ISO Sertraline results in decreased expression of UBE2G1 mRNA CTD PMID:24865413 NCBI chr10:59,173,268...59,254,458
Ensembl chr10:59,173,268...59,254,453 		JBrowse link
G Ube4b ubiquitination factor E4B decreases expression ISO Sertraline results in decreased expression of UBE4B mRNA CTD PMID:24865413 NCBI chr 5:166,156,033...166,259,069
Ensembl chr 5:166,156,033...166,259,069 		JBrowse link
G Ubqln1 ubiquilin 1 increases expression ISO Sertraline results in increased expression of UBQLN1 mRNA CTD PMID:24865413 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO UGT2B7 protein results in increased glucuronidation of and results in increased metabolism of Sertraline CTD PMID:15547048 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO Sertraline results in increased expression of VCAM1 protein CTD PMID:15932816 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Sertraline results in increased expression of WIPI1 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr10:97,859,730...97,896,949
Ensembl chr10:97,859,727...97,896,525 		JBrowse link
G Xbp1 X-box binding protein 1 increases splicing ISO Sertraline results in increased splicing of XBP1 mRNA CTD PMID:24865413 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
tamibarotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan affects expression ISO tamibarotene affects the expression of ACAN mRNA CTD PMID:15498508 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441 		JBrowse link
G Acvrl1 activin A receptor like type 1 decreases expression ISO tamibarotene results in decreased expression of ACVRL1 mRNA CTD PMID:15498508 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335 		JBrowse link
G Ada adenosine deaminase increases expression ISO tamibarotene results in increased expression of ADA mRNA CTD PMID:15498508 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 increases expression ISO tamibarotene results in increased expression of ADGRE1 mRNA CTD PMID:15498508 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865 		JBrowse link
G Adnp2 ADNP homeobox 2 affects expression ISO tamibarotene affects the expression of ADNP2 mRNA CTD PMID:15498508 NCBI chr18:76,637,415...76,661,186
Ensembl chr18:76,637,785...76,653,056 		JBrowse link
G Adora3 adenosine A3 receptor affects expression ISO tamibarotene affects the expression of ADORA3 mRNA CTD PMID:15498508 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803 		JBrowse link
G Agps alkylglycerone phosphate synthase affects expression ISO tamibarotene affects the expression of AGPS mRNA CTD PMID:15498508 NCBI chr 3:62,648,352...62,749,250
Ensembl chr 3:62,648,447...62,749,153 		JBrowse link
G Agt angiotensinogen multiple interactions ISO tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein] CTD PMID:16484594 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO tamibarotene results in decreased expression of AHNAK mRNA CTD PMID:15498508 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015 		JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO tamibarotene results in increased expression of AIF1 mRNA CTD PMID:15498508 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448 		JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO tamibarotene results in decreased expression of AK4 mRNA CTD PMID:15498508 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897 		JBrowse link
G Akap2 A-kinase anchoring protein 2 affects expression ISO tamibarotene affects the expression of PALM2AKAP2 mRNA CTD PMID:15498508 NCBI chr 5:74,874,245...74,985,789
Ensembl chr 5:74,874,306...74,982,401 		JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression ISO tamibarotene results in decreased expression of AKAP9 mRNA CTD PMID:15498508 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO tamibarotene results in increased expression of ALAS1 mRNA CTD PMID:15498508 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects expression ISO tamibarotene affects the expression of ALDH1B1 mRNA CTD PMID:15498508 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358 		JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein decreases expression ISO tamibarotene results in decreased expression of ALMS1 mRNA CTD PMID:15498508 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO tamibarotene results in increased expression of ALOX5AP mRNA CTD PMID:15498508 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 decreases expression ISO tamibarotene results in decreased expression of AMD1 mRNA CTD PMID:15498508 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694 		JBrowse link
G Ankrd17 ankyrin repeat domain 17 decreases expression ISO tamibarotene results in decreased expression of ANKRD17 mRNA CTD PMID:15498508 NCBI chr14:19,291,025...19,431,521
Ensembl chr14:19,318,565...19,431,515 		JBrowse link
G Anxa2 annexin A2 decreases expression ISO tamibarotene results in decreased expression of ANXA2 mRNA CTD PMID:15498508 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 increases expression ISO tamibarotene results in increased expression of AP1S2 mRNA CTD PMID:15498508 NCBI chr  X:32,329,883...32,376,301
Ensembl chr  X:32,329,598...32,355,307 		JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 affects expression ISO tamibarotene affects the expression of APBB3 mRNA CTD PMID:15498508 NCBI chr18:29,497,865...29,504,995
Ensembl chr18:29,497,863...29,504,995 		JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression ISO tamibarotene results in decreased expression of APC mRNA CTD PMID:15498508 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531 		JBrowse link
G Aqp7 aquaporin 7 affects expression ISO tamibarotene affects the expression of AQP7 mRNA CTD PMID:15498508 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239 		JBrowse link
G Arf6 ADP-ribosylation factor 6 affects expression ISO tamibarotene affects the expression of ARF6 mRNA CTD PMID:15498508 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255 		JBrowse link
G Arhgap4 Rho GTPase activating protein 4 increases expression ISO tamibarotene results in increased expression of ARHGAP4 mRNA CTD PMID:15498508 NCBI chr  X:156,873,094...156,888,762
Ensembl chr  X:156,873,849...156,888,761 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO tamibarotene results in increased expression of ARHGAP45 mRNA CTD PMID:15498508 NCBI chr 7:12,541,032...12,741,314
Ensembl chr 7:12,541,061...12,741,296 		JBrowse link
G Arhgap8 Rho GTPase activating protein 8 increases expression ISO tamibarotene results in increased expression of ARHGAP8 mRNA CTD PMID:17229644 NCBI chr 7:125,732,300...125,797,149
Ensembl chr 7:125,731,275...125,795,980 		JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C decreases expression ISO tamibarotene results in decreased expression of ARL4C mRNA CTD PMID:15498508 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO tamibarotene results in increased expression of ASB2 mRNA CTD PMID:17229644 NCBI chr 6:127,212,325...127,248,451
Ensembl chr 6:127,212,273...127,248,372 		JBrowse link
G Atp13a3 ATPase 13A3 affects expression ISO tamibarotene affects the expression of ATP13A3 mRNA CTD PMID:15498508 NCBI chr11:73,936,750...73,963,852
Ensembl chr11:73,936,750...73,963,852 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 affects expression ISO tamibarotene affects the expression of ATP1A3 mRNA CTD PMID:15498508 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 affects expression ISO tamibarotene affects the expression of ATP2B1 mRNA CTD PMID:15498508 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression ISO tamibarotene results in increased expression of ATP6V0A1 mRNA CTD PMID:15498508 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 decreases expression ISO tamibarotene results in decreased expression of ATP6V0A2 mRNA CTD PMID:15498508 NCBI chr12:37,368,321...37,398,233
Ensembl chr12:37,363,906...37,425,596 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression ISO tamibarotene affects the expression of ATP6V1A mRNA CTD PMID:15498508 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634 		JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 affects expression ISO tamibarotene affects the expression of ATPAF2 mRNA CTD PMID:15498508 NCBI chr10:46,768,539...46,783,889
Ensembl chr10:46,768,539...46,783,889 		JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO tamibarotene results in decreased expression of ATRX mRNA CTD PMID:15498508 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878 		JBrowse link
G Atxn7l3b ataxin 7-like 3B affects expression ISO tamibarotene affects the expression of ATXN7L3B mRNA CTD PMID:15498508 NCBI chr 7:55,600,879...55,604,403
Ensembl chr 7:55,600,889...55,604,403 		JBrowse link
G Axin1 axin 1 increases expression ISO tamibarotene results in increased expression of AXIN1 mRNA CTD PMID:15498508
G Azin1 antizyme inhibitor 1 affects expression ISO tamibarotene affects the expression of AZIN1 mRNA CTD PMID:15498508 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO tamibarotene results in increased expression of BAK1 mRNA CTD PMID:15498508 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 affects expression ISO tamibarotene affects the expression of BCAT1 mRNA CTD PMID:15498508 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795 		JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO tamibarotene results in decreased expression of BCL11A mRNA CTD PMID:15498508 NCBI chr14:108,826,717...108,921,197
Ensembl chr14:108,826,831...108,921,669 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
affects expression		 ISO Triiodothyronine promotes the reaction [tamibarotene results in decreased expression of BCL2 mRNA]
tamibarotene affects the expression of BCL2 mRNA		 CTD PMID:11201846 PMID:15498508 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression
multiple interactions		 ISO tamibarotene results in increased expression of BCL2A1 mRNA; tamibarotene results in increased expression of BCL2A1A mRNA
Triiodothyronine promotes the reaction [tamibarotene results in increased expression of BCL2A1A mRNA]		 CTD PMID:11201846 PMID:15498508 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483 		JBrowse link
G Bcl7a BAF chromatin remodeling complex subunit BCL7A decreases expression ISO tamibarotene results in decreased expression of BCL7A mRNA CTD PMID:15498508 NCBI chr12:38,659,294...38,691,191
Ensembl chr12:38,662,303...38,691,075 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO tamibarotene results in decreased expression of BCLAF1 mRNA CTD PMID:15498508 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression		 ISO
EXP		 [tamibarotene co-treated with BDNF] results in increased expression of NTRK2
BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]; BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]; BDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein]
tamibarotene results in increased expression of BDNF mRNA		 CTD PMID:19182380 PMID:19457078 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO tamibarotene affects the expression of BHLHE40 mRNA CTD PMID:15498508 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319 		JBrowse link
G Blmh bleomycin hydrolase decreases expression ISO tamibarotene results in decreased expression of BLMH mRNA CTD PMID:15498508 NCBI chr10:63,197,367...63,240,447
Ensembl chr10:63,197,364...63,240,332 		JBrowse link
G Bpi bactericidal/permeability-increasing protein increases expression ISO tamibarotene results in increased expression of BPI mRNA CTD PMID:15498508 NCBI chr 3:154,741,627...154,768,584
Ensembl chr 3:154,741,631...154,768,640 		JBrowse link
G Bptf bromodomain PHD finger transcription factor affects expression ISO tamibarotene affects the expression of BPTF mRNA CTD PMID:15498508 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789 		JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO tamibarotene results in decreased expression of BRCA1 mRNA CTD PMID:15498508 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681 		JBrowse link
G Brca2 BRCA2, DNA repair associated affects expression
decreases expression		 ISO tamibarotene affects the expression of BRCA2 mRNA
tamibarotene results in decreased expression of BRCA2 mRNA		 CTD PMID:15498508 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748 		JBrowse link
G Brd3 bromodomain containing 3 affects expression ISO tamibarotene affects the expression of BRD3 mRNA CTD PMID:15498508 NCBI chr 3:5,995,204...6,054,467
Ensembl chr 3:5,997,315...6,054,483 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 affects expression ISO tamibarotene affects the expression of BST2 mRNA CTD PMID:15498508 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353 		JBrowse link
G Btf3 basic transcription factor 3 affects expression ISO tamibarotene affects the expression of BTF3 mRNA CTD PMID:15498508 NCBI chr 2:28,417,316...28,424,436
Ensembl chr 2:28,417,579...28,423,762 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO tamibarotene results in increased expression of BTG2 mRNA CTD PMID:15498508 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982 		JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression ISO tamibarotene results in increased expression of CADM1 mRNA CTD PMID:15498508 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722 		JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I increases expression ISO tamibarotene results in increased expression of CAMK1 mRNA CTD PMID:15498508 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177 		JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO tamibarotene results in increased expression of CAMTA2 mRNA CTD PMID:15498508 NCBI chr10:57,291,192...57,309,638
Ensembl chr10:57,291,192...57,309,298 		JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO tamibarotene results in increased expression of CAPG mRNA CTD PMID:15498508 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446 		JBrowse link
G Caprin1 cell cycle associated protein 1 decreases expression ISO tamibarotene results in decreased expression of CAPRIN1 mRNA CTD PMID:15498508 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617 		JBrowse link
G Casp9 caspase 9 increases expression ISO tamibarotene results in increased expression of CASP9 mRNA CTD PMID:15498508 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cbx3 chromobox 3 affects expression ISO tamibarotene affects the expression of CBX3 mRNA CTD PMID:15498508 NCBI chr 4:81,243,809...81,257,898
Ensembl chr 4:81,244,469...81,257,897 		JBrowse link
G Ccdc22 coiled-coil domain containing 22 affects expression ISO tamibarotene affects the expression of CCDC22 mRNA CTD PMID:15498508 NCBI chr  X:15,742,978...15,754,925
Ensembl chr  X:15,742,978...15,754,925 		JBrowse link
G Ccdc93 coiled-coil domain containing 93 decreases expression ISO tamibarotene results in decreased expression of CCDC93 mRNA CTD PMID:15498508 NCBI chr13:37,400,455...37,473,973
Ensembl chr13:37,400,476...37,468,840 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO tamibarotene results in increased expression of CCL4 mRNA CTD PMID:15498508 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
decreases expression		 ISO tamibarotene results in increased expression of CCL5 mRNA
tamibarotene results in decreased expression of CCL5 mRNA		 CTD PMID:15498508 PMID:20861477 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression ISO tamibarotene results in decreased expression of CCL6 mRNA CTD PMID:20861477 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782 		JBrowse link
G Ccnd1 cyclin D1 increases expression ISO tamibarotene results in increased expression of CCND1 mRNA CTD PMID:15498508 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccnf cyclin F decreases expression ISO tamibarotene results in decreased expression of CCNF mRNA CTD PMID:15498508 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935 		JBrowse link
G Ccng1 cyclin G1 affects expression ISO tamibarotene affects the expression of CCNG1 mRNA CTD PMID:15498508 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO tamibarotene results in increased expression of CCR1 mRNA CTD PMID:15498508 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Cd22 CD22 molecule affects expression ISO tamibarotene affects the expression of CD22 mRNA CTD PMID:15498508 NCBI chr 1:89,313,475...89,329,902
Ensembl chr 1:89,314,558...89,329,418 		JBrowse link
G Cd300a Cd300a molecule increases expression ISO tamibarotene results in increased expression of CD300A mRNA CTD PMID:15498508 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]
tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]		 CTD PMID:16484594 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cd38 CD38 molecule increases expression ISO tamibarotene results in increased expression of CD38 mRNA; tamibarotene results in increased expression of CD38 protein CTD PMID:15498508 PMID:21393419 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672 		JBrowse link
G Cd3d CD3d molecule decreases expression ISO tamibarotene results in decreased expression of CD3D mRNA CTD PMID:20861477 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110 		JBrowse link
G Cd3g CD3g molecule decreases expression ISO tamibarotene results in decreased expression of CD3G mRNA CTD PMID:20861477 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression
affects expression		 ISO tamibarotene results in decreased expression of CD44 mRNA
tamibarotene affects the expression of CD44 mRNA		 CTD PMID:15498508 PMID:17229644 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Cd53 Cd53 molecule increases expression ISO tamibarotene results in increased expression of CD53 mRNA CTD PMID:15498508 NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087 		JBrowse link
G Cd68 Cd68 molecule decreases expression ISO tamibarotene results in decreased expression of CD68 mRNA CTD PMID:20861477 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640 		JBrowse link
G Cd69 Cd69 molecule affects expression ISO tamibarotene affects the expression of CD69 mRNA CTD PMID:15498508 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084 		JBrowse link
G Cd74 CD74 molecule increases expression ISO tamibarotene results in increased expression of CD74 mRNA CTD PMID:17229644 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849 		JBrowse link
G Cd79a CD79a molecule increases expression ISO tamibarotene results in increased expression of CD79A mRNA CTD PMID:17229644 NCBI chr 1:81,763,609...81,768,039
Ensembl chr 1:81,763,614...81,767,980 		JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO tamibarotene results in decreased expression of CDC25A mRNA CTD PMID:15498508 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO tamibarotene results in decreased expression of CDC6 mRNA CTD PMID:15498508 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402 		JBrowse link
G Cdk10 cyclin-dependent kinase 10 affects expression ISO tamibarotene affects the expression of CDK10 mRNA CTD PMID:15498508 NCBI chr19:56,024,903...56,032,610
Ensembl chr19:56,024,903...56,032,605 		JBrowse link
G Cdk8 cyclin-dependent kinase 8 affects expression ISO tamibarotene affects the expression of CDK8 mRNA CTD PMID:15498508 NCBI chr12:10,496,273...10,561,335 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO tamibarotene results in increased expression of CDKN1A mRNA CTD PMID:17229644 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression
multiple interactions		 ISO tamibarotene results in increased expression of CEACAM6 mRNA
CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]		 CTD PMID:27737899 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO tamibarotene results in increased expression of CEBPB mRNA CTD PMID:15498508 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO tamibarotene results in increased expression of CEBPD mRNA CTD PMID:15498508 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146 		JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon increases expression
multiple interactions		 ISO tamibarotene results in increased expression of CEBPE mRNA
CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]		 CTD PMID:27737899 NCBI chr15:33,356,119...33,357,517
Ensembl chr15:33,355,947...33,358,138 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO tamibarotene results in decreased expression of CEBPG mRNA CTD PMID:15498508 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656 		JBrowse link
G Celf1 CUGBP, Elav-like family member 1 affects expression ISO tamibarotene affects the expression of CELF1 mRNA CTD PMID:15498508 NCBI chr 3:79,768,900...79,844,548
Ensembl chr 3:79,823,945...79,842,082 		JBrowse link
G Cep135 centrosomal protein 135 decreases expression ISO tamibarotene results in decreased expression of CEP135 mRNA CTD PMID:15498508 NCBI chr14:34,052,168...34,115,763
Ensembl chr14:34,051,003...34,115,273 		JBrowse link
G Chka choline kinase alpha decreases expression ISO tamibarotene results in decreased expression of CHKA mRNA CTD PMID:15498508 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO tamibarotene results in increased expression of CIITA mRNA CTD PMID:17229644 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608 		JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression ISO tamibarotene results in decreased expression of CLCNKA mRNA CTD PMID:15498508 NCBI chr 5:159,931,497...159,946,483
Ensembl chr 5:159,931,511...159,946,446 		JBrowse link
G Cltb clathrin, light chain B increases expression ISO tamibarotene results in increased expression of CLTB mRNA CTD PMID:15498508 NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989 		JBrowse link
G Col11a2 collagen type XI alpha 2 chain affects expression ISO tamibarotene affects the expression of COL11A2 mRNA CTD PMID:15498508 NCBI chr20:3,829,324...3,859,022
Ensembl chr20:3,830,164...3,859,018 		JBrowse link
G Coro1a coronin 1A increases expression ISO tamibarotene results in increased expression of CORO1A mRNA CTD PMID:15498508 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO tamibarotene affects the expression of CREB1 mRNA CTD PMID:15498508 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO tamibarotene results in increased expression of CREB3 mRNA CTD PMID:15498508 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression ISO tamibarotene results in increased expression of CREG1 mRNA CTD PMID:15498508 NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [tamibarotene co-treated with CSF3 protein] results in increased expression of CEACAM8 mRNA; CSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]; CSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of RARB mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of RARB mRNA] CTD PMID:27737899 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression ISO tamibarotene affects the expression of CSRP1 mRNA CTD PMID:15498508 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051 		JBrowse link
G Cst3 cystatin C increases expression ISO tamibarotene results in increased expression of CST3 mRNA CTD PMID:15498508 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615 		JBrowse link
G Ctif cap binding complex dependent translation initiation factor decreases expression ISO tamibarotene results in decreased expression of CTIF mRNA CTD PMID:15498508 NCBI chr18:71,467,381...71,701,423
Ensembl chr18:71,463,486...71,829,881 		JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO tamibarotene results in decreased expression of CTNNAL1 mRNA CTD PMID:15498508 NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070 		JBrowse link
G Ctsa cathepsin A increases expression ISO tamibarotene results in increased expression of CTSA mRNA CTD PMID:17229644 NCBI chr 3:161,298,750...161,304,627
Ensembl chr 3:161,298,962...161,304,625 		JBrowse link
G Ctsd cathepsin D increases expression ISO tamibarotene results in increased expression of CTSD mRNA CTD PMID:15498508 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451 		JBrowse link
G Cul1 cullin 1 decreases expression ISO tamibarotene results in decreased expression of CUL1 mRNA CTD PMID:15498508 NCBI chr 4:77,211,814...77,283,369
Ensembl chr 4:77,211,692...77,280,250 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO tamibarotene results in decreased expression of CXCL10 mRNA CTD PMID:20861477 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO tamibarotene results in decreased expression of CXCL9 mRNA CTD PMID:20861477 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression		 ISO tamibarotene results in increased uptake of and affects the localization of CXCR4 protein
tamibarotene results in decreased expression of CXCR4 mRNA		 CTD PMID:20141446 PMID:20861477 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO tamibarotene results in increased expression of CXCR5 mRNA CTD PMID:15498508 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671 		JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO tamibarotene results in increased expression of CYBA mRNA CTD PMID:15498508 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO tamibarotene results in increased expression of CYBB mRNA CTD PMID:15498508 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO tamibarotene inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:16289102 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920 		JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression ISO tamibarotene results in decreased expression of DAAM1 mRNA CTD PMID:15498508 NCBI chr 6:94,606,675...94,739,026
Ensembl chr 6:94,636,222...94,739,026 		JBrowse link
G Dagla diacylglycerol lipase, alpha affects expression ISO tamibarotene affects the expression of DAGLA mRNA CTD PMID:15498508 NCBI chr 1:226,297,013...226,353,712
Ensembl chr 1:226,297,016...226,353,611 		JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO tamibarotene results in increased expression of DAPK2 mRNA CTD PMID:15498508 NCBI chr 8:71,822,107...71,941,941
Ensembl chr 8:71,822,129...71,941,910 		JBrowse link
G Ddx18 DEAD-box helicase 18 affects expression ISO tamibarotene affects the expression of DDX18 mRNA CTD PMID:15498508 NCBI chr13:37,522,558...37,536,066
Ensembl chr13:37,522,561...37,536,066 		JBrowse link
G Ddx21 DExD-box helicase 21 decreases expression ISO tamibarotene results in decreased expression of DDX21 mRNA CTD PMID:15498508 NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632 		JBrowse link
G Ddx51 DEAD-box helicase 51 affects expression ISO tamibarotene affects the expression of DDX51 mRNA CTD PMID:15498508 NCBI chr12:52,067,183...52,072,249
Ensembl chr12:52,067,183...52,072,108 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO tamibarotene results in increased expression of DHRS3 mRNA CTD PMID:15498508 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 affects expression ISO tamibarotene affects the expression of DMBT1 mRNA CTD PMID:15498508 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705 		JBrowse link
G Dok2 docking protein 2 increases expression ISO tamibarotene results in increased expression of DOK2 mRNA CTD PMID:15498508 NCBI chr15:52,449,884...52,455,414
Ensembl chr15:52,451,161...52,456,409 		JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression ISO tamibarotene results in increased expression of DPH1 mRNA CTD PMID:15498508 NCBI chr10:62,019,379...62,032,384
Ensembl chr10:62,019,379...62,032,407 		JBrowse link
G Dst dystonin decreases expression ISO tamibarotene results in decreased expression of DST mRNA CTD PMID:15498508 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273 		JBrowse link
G Dusp10 dual specificity phosphatase 10 decreases expression ISO tamibarotene results in decreased expression of DUSP10 mRNA CTD PMID:17229644 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression ISO tamibarotene results in decreased expression of DVL1 mRNA CTD PMID:15498508 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945 		JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 decreases expression ISO tamibarotene results in decreased expression of DYNC1LI2 mRNA CTD PMID:15498508 NCBI chr19:740,007...762,897
Ensembl chr19:740,028...762,897 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression ISO tamibarotene affects the expression of ECI1 mRNA CTD PMID:15498508 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913 		JBrowse link
G Edn1 endothelin 1 increases expression ISO tamibarotene results in increased expression of EDN1 mRNA CTD PMID:15498508 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Edn2 endothelin 2 increases expression ISO tamibarotene results in increased expression of EDN2 mRNA CTD PMID:15498508 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792 		JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 decreases expression ISO tamibarotene results in decreased expression of EDRF1 mRNA CTD PMID:15498508 NCBI chr 1:205,706,023...205,743,676
Ensembl chr 1:205,706,468...205,743,653 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO tamibarotene results in increased expression of EEF1A1 mRNA CTD PMID:15498508 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 decreases expression ISO tamibarotene results in decreased expression of EEF1E1 mRNA CTD PMID:15498508 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161 		JBrowse link
G Egr3 early growth response 3 increases expression ISO tamibarotene results in increased expression of EGR3 mRNA CTD PMID:15498508 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A affects expression ISO tamibarotene affects the expression of EIF2A mRNA CTD PMID:15498508 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520 		JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma affects expression ISO tamibarotene affects the expression of EIF2S3 mRNA CTD PMID:15498508 NCBI chr  X:63,268,106...63,291,125
Ensembl chr  X:63,268,037...63,292,092 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO tamibarotene results in decreased expression of EIF3A mRNA CTD PMID:15498508 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO tamibarotene results in decreased expression of EIF4A2 mRNA CTD PMID:15498508 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression ISO tamibarotene results in decreased expression of EIF4B mRNA CTD PMID:15498508 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452 		JBrowse link
G Epx eosinophil peroxidase decreases expression ISO tamibarotene results in decreased expression of EPX mRNA CTD PMID:15498508 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774 		JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit decreases expression ISO tamibarotene results in decreased expression of ERCC8 mRNA CTD PMID:15498508 NCBI chr 2:39,434,617...39,473,392
Ensembl chr 2:39,434,634...39,472,017 		JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO tamibarotene results in increased activity of ESR1 protein CTD PMID:25257666 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Evx1 even-skipped homeobox 1 decreases expression ISO tamibarotene results in decreased expression of EVX1 mRNA CTD PMID:15498508 NCBI chr 4:82,370,829...82,374,313
Ensembl chr 4:82,370,997...82,375,374 		JBrowse link
G Exoc3 exocyst complex component 3 affects expression ISO tamibarotene affects the expression of EXOC3 mRNA CTD PMID:15498508 NCBI chr 1:31,700,953...31,731,726
Ensembl chr 1:31,700,953...31,731,815 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA] CTD PMID:15020266 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Fam89b family with sequence similarity 89, member B increases expression ISO tamibarotene results in increased expression of FAM89B mRNA CTD PMID:15498508 NCBI chr 1:221,085,894...221,087,449
Ensembl chr 1:221,085,895...221,087,449 		JBrowse link
G Fas Fas cell surface death receptor increases activity ISO tamibarotene results in increased activity of FAS protein CTD PMID:15703382 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Fat1 FAT atypical cadherin 1 affects expression ISO tamibarotene affects the expression of FAT1 mRNA CTD PMID:15498508 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921 		JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO tamibarotene results in decreased expression of FBN2 mRNA CTD PMID:15498508 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO tamibarotene results in increased expression of FBP1 mRNA CTD PMID:15498508 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig increases expression ISO tamibarotene results in increased expression of FCER1G mRNA CTD PMID:15498508 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326 		JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia affects expression ISO tamibarotene affects the expression of FCGR1A mRNA CTD PMID:15498508 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb affects expression ISO tamibarotene affects the expression of FCGR2B mRNA CTD PMID:15498508 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase affects expression ISO tamibarotene affects the expression of FES mRNA CTD PMID:15498508 NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO tamibarotene results in decreased expression of FGFR1 mRNA CTD PMID:15498508 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of FGR mRNA CTD PMID:15498508 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO tamibarotene results in decreased expression of FKBP5 mRNA CTD PMID:15498508 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020 		JBrowse link
G Flot1 flotillin 1 increases expression ISO tamibarotene results in increased expression of FLOT1 mRNA CTD PMID:15498508 NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO tamibarotene results in increased expression of FOSB mRNA CTD PMID:15498508 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Foxo4 forkhead box O4 increases expression ISO tamibarotene results in increased expression of FOXO4 mRNA CTD PMID:15498508 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158 		JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO tamibarotene results in decreased expression of FOXP3 mRNA CTD PMID:22077062 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522 		JBrowse link
G Fuca1 alpha-L-fucosidase 1 increases expression ISO tamibarotene results in increased expression of FUCA1 mRNA CTD PMID:15498508 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544 		JBrowse link
G Fut4 fucosyltransferase 4 increases expression ISO tamibarotene results in increased expression of FUT4 mRNA CTD PMID:15498508 NCBI chr 8:13,258,768...13,262,729
Ensembl chr 8:13,258,768...13,262,729 		JBrowse link
G Fyb1 FYN binding protein 1 affects expression ISO tamibarotene affects the expression of FYB1 mRNA CTD PMID:15498508 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO tamibarotene results in decreased expression of FYN mRNA CTD PMID:15498508 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO tamibarotene results in decreased expression of GADD45A mRNA CTD PMID:15498508 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Galk2 galactokinase 2 decreases expression ISO tamibarotene results in decreased expression of GALK2 mRNA CTD PMID:15498508 NCBI chr 3:118,137,097...118,268,838
Ensembl chr 3:118,136,838...118,268,836 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase increases expression ISO tamibarotene results in increased expression of GALT mRNA CTD PMID:15498508 NCBI chr 5:58,144,679...58,147,946
Ensembl chr 5:58,144,705...58,147,929 		JBrowse link
G Gata2 GATA binding protein 2 decreases expression ISO tamibarotene results in decreased expression of GATA2 mRNA CTD PMID:15498508 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Gatad1 GATA zinc finger domain containing 1 decreases expression ISO tamibarotene results in decreased expression of GATAD1 mRNA CTD PMID:15498508 NCBI chr 4:27,647,005...27,658,533
Ensembl chr 4:27,647,335...27,657,167 		JBrowse link
G Gatc glutamyl-tRNA amidotransferase subunit C affects expression ISO tamibarotene affects the expression of GATC mRNA CTD PMID:15498508 NCBI chr12:47,031,545...47,039,556
Ensembl chr12:46,989,951...47,039,542
Ensembl chr12:46,989,951...47,039,542 		JBrowse link
G Gca grancalcin increases expression ISO tamibarotene results in increased expression of GCA mRNA CTD PMID:15498508 NCBI chr 3:48,625,965...48,661,317
Ensembl chr 3:48,626,038...48,661,317 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP tamibarotene results in increased expression of GFAP CTD PMID:19182380 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506 		JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 affects expression ISO tamibarotene affects the expression of GFPT1 mRNA CTD PMID:15498508 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO tamibarotene results in increased expression of GGT1 mRNA CTD PMID:15498508 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068 		JBrowse link
G Glod4 glyoxalase domain containing 4 affects expression ISO tamibarotene affects the expression of GLOD4 mRNA CTD PMID:15498508 NCBI chr10:64,379,922...64,398,263
Ensembl chr10:64,379,921...64,398,294 		JBrowse link
G Glrx glutaredoxin increases expression ISO tamibarotene results in increased expression of GLRX mRNA CTD PMID:15498508 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944 		JBrowse link
G Gnaq G protein subunit alpha q affects expression ISO tamibarotene affects the expression of GNAQ mRNA CTD PMID:15498508 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786 		JBrowse link
G Gng4 G protein subunit gamma 4 decreases expression ISO tamibarotene results in decreased expression of GNG4 mRNA CTD PMID:15498508 NCBI chr17:90,266,571...90,316,278
Ensembl chr17:90,266,794...90,315,492 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression ISO tamibarotene affects the expression of GPX1 mRNA CTD PMID:15498508 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression
affects expression		 ISO tamibarotene results in increased expression of GRINA mRNA
tamibarotene affects the expression of GRINA mRNA		 CTD PMID:15498508 PMID:17229644 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916 		JBrowse link
G Grn granulin precursor increases expression ISO tamibarotene results in increased expression of GRN mRNA CTD PMID:15498508 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects expression ISO tamibarotene affects the expression of GSK3B mRNA CTD PMID:15498508 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Gsn gelsolin increases expression ISO tamibarotene results in increased expression of GSN mRNA CTD PMID:15498508 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO tamibarotene results in increased expression of GSTM1 mRNA CTD PMID:15498508 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO tamibarotene results in increased expression of GSTO1 mRNA CTD PMID:15498508 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387 		JBrowse link
G H4c3 H4 clustered histone 3 affects expression ISO tamibarotene affects the expression of H4C3 mRNA CTD PMID:15498508 NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262 		JBrowse link
G H4f3 H1.3 linker histone, cluster member affects expression ISO tamibarotene affects the expression of H1-3 mRNA CTD PMID:15498508 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of HCK mRNA CTD PMID:15498508 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 decreases expression ISO tamibarotene results in decreased expression of HIPK1 mRNA CTD PMID:15498508 NCBI chr 2:206,224,015...206,274,910
Ensembl chr 2:206,224,015...206,274,079 		JBrowse link
G Hira histone cell cycle regulator affects expression ISO tamibarotene affects the expression of HIRA mRNA CTD PMID:15498508 NCBI chr11:86,168,196...86,276,430
Ensembl chr11:86,168,196...86,276,430 		JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 increases expression ISO tamibarotene results in increased expression of H2AC18 mRNA CTD PMID:15498508 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201 		JBrowse link
G Hk3 hexokinase 3 increases expression ISO tamibarotene results in increased expression of HK3 mRNA CTD PMID:15498508 NCBI chr17:10,134,726...10,152,976
Ensembl chr17:10,137,974...10,152,956 		JBrowse link
G Hlx H2.0-like homeobox affects expression ISO tamibarotene affects the expression of HLX mRNA CTD PMID:15498508 NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 affects expression ISO tamibarotene affects the expression of HMGCS1 mRNA CTD PMID:15498508 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase increases expression ISO tamibarotene results in increased expression of HPD mRNA CTD PMID:15498508 NCBI chr12:38,828,606...38,839,956
Ensembl chr12:38,828,444...38,839,969 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase affects expression ISO tamibarotene affects the expression of HPGD mRNA CTD PMID:15498508 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects expression ISO tamibarotene affects the expression of HSP90AB1 mRNA CTD PMID:15498508 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO tamibarotene results in decreased expression of HSP90B1 mRNA CTD PMID:15498508 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533 		JBrowse link
G Ice1 interactor of little elongation complex ELL subunit 1 affects expression ISO tamibarotene affects the expression of ICE1 mRNA CTD PMID:15498508 NCBI chr 1:35,280,481...35,322,769
Ensembl chr 1:35,280,701...35,319,182 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO tamibarotene results in increased expression of IER3 mRNA CTD PMID:15498508 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769 		JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO tamibarotene results in increased expression of IFI35 mRNA CTD PMID:15498508 NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO tamibarotene results in increased expression of IFIT3 mRNA CTD PMID:15498508 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
increases response to substance		 ISO
EXP		 tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]
tamibarotene inhibits the reaction [MBP results in increased expression of IFNG mRNA]
tamibarotene results in decreased expression of IFNG mRNA
IFNG results in increased susceptibility to tamibarotene
tamibarotene results in decreased expression of IFNG; tamibarotene results in decreased expression of IFNG protein		 CTD PMID:10828746 PMID:11043609 PMID:11501064 PMID:20861477 PMID:22077062 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO tamibarotene affects the expression of IGFBP2 mRNA CTD PMID:15498508 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO tamibarotene results in increased expression of IGFBP3 mRNA; tamibarotene results in increased expression of IGFBP3 protein CTD PMID:10766424 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 affects expression ISO tamibarotene affects the expression of IGHG1 mRNA CTD PMID:15498508 NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 affects expression ISO tamibarotene affects the expression of IKZF1 mRNA CTD PMID:15498508 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP tamibarotene inhibits the reaction [MBP results in increased expression of IL10 mRNA] CTD PMID:11501064 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO tamibarotene results in increased expression of IL10RB mRNA CTD PMID:15498508 NCBI chr11:31,560,301...31,582,457
Ensembl chr11:31,560,530...31,582,457 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO IL17A affects the reaction [tamibarotene results in decreased expression of TGFB1 mRNA] CTD PMID:22077062 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il17rd interleukin 17 receptor D decreases expression ISO tamibarotene results in decreased expression of IL17RD mRNA CTD PMID:20861477 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression		 ISO tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 protein]
tamibarotene results in decreased expression of IL1B mRNA
tamibarotene results in increased expression of IL1B mRNA		 CTD PMID:9873234 PMID:15498508 PMID:20861477 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il21 interleukin 21 multiple interactions ISO tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] CTD PMID:22077062 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356 		JBrowse link
G Il27 interleukin 27 decreases expression ISO tamibarotene results in decreased expression of IL27 mRNA CTD PMID:20861477 NCBI chr 1:198,003,615...198,010,112
Ensembl chr 1:198,003,683...198,008,893 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma decreases expression ISO tamibarotene results in decreased expression of IL2RG mRNA CTD PMID:20861477 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP HX 600 promotes the reaction [tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]]; LE 540 inhibits the reaction [tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]]; tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 mRNA]; tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein] CTD PMID:11233995 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression		 ISO
EXP		 tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein]; tamibarotene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]
tamibarotene results in decreased expression of IL6 mRNA
tamibarotene affects the reaction [MBP results in increased expression of IL6 mRNA]
tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 protein]		 CTD PMID:9873234 PMID:10828746 PMID:11043609 PMID:11501064 PMID:16484594 PMID:17229644 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO tamibarotene results in decreased expression of IL6RA protein CTD PMID:20861477 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
G Il7 interleukin 7 decreases expression ISO tamibarotene results in decreased expression of IL7 mRNA CTD PMID:20861477 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977 		JBrowse link
G Il7r interleukin 7 receptor decreases expression ISO tamibarotene results in decreased expression of IL7R mRNA CTD PMID:20861477
G Ilf3 interleukin enhancer binding factor 3 decreases expression ISO tamibarotene results in decreased expression of ILF3 mRNA CTD PMID:15498508 NCBI chr 8:22,402,877...22,440,984
Ensembl chr 8:22,402,890...22,440,885 		JBrowse link
G Ilk integrin-linked kinase increases expression ISO tamibarotene results in increased expression of ILK mRNA CTD PMID:15498508 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189 		JBrowse link
G Ipo5 importin 5 affects expression ISO tamibarotene affects the expression of IPO5 mRNA CTD PMID:15498508 NCBI chr15:106,243,110...106,293,326
Ensembl chr15:106,257,650...106,292,112 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO tamibarotene results in increased expression of IRAK2 mRNA CTD PMID:17229644 NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053 		JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO tamibarotene results in increased expression of IRF1 mRNA CTD PMID:15498508 PMID:17229644 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531 		JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO tamibarotene results in increased expression of IRF7 mRNA CTD PMID:15498508 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456 		JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO tamibarotene results in increased expression of IRF9 mRNA CTD PMID:15498508 NCBI chr15:34,282,936...34,288,981
Ensembl chr15:34,282,936...34,288,138 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO tamibarotene affects the expression of ISG15 mRNA CTD PMID:15498508 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 affects expression ISO tamibarotene affects the expression of ISG20 mRNA CTD PMID:15498508 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946 		JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO tamibarotene results in increased expression of ITGA3 mRNA CTD PMID:17229644 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497 		JBrowse link
G Itga4 integrin subunit alpha 4 affects expression ISO tamibarotene affects the expression of ITGA4 mRNA CTD PMID:15498508 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960 		JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
affects expression		 ISO tamibarotene results in increased expression of ITGAM mRNA; tamibarotene results in increased expression of ITGAM protein
CSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]; Triiodothyronine promotes the reaction [tamibarotene results in increased expression of ITGAM protein]
tamibarotene affects the expression of ITGAM protein		 CTD PMID:11201846 PMID:15498508 PMID:21393419 PMID:27737899 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression
multiple interactions
decreases expression		 ISO tamibarotene results in increased expression of ITGB2 mRNA
CSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]		 CTD PMID:15498508 PMID:27737899 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G Itgb7 integrin subunit beta 7 increases expression ISO tamibarotene results in increased expression of ITGB7 mRNA CTD PMID:15498508 PMID:17229644 NCBI chr 7:143,820,236...143,837,802
Ensembl chr 7:143,820,900...143,837,780 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 affects expression ISO tamibarotene affects the expression of ITPR2 mRNA CTD PMID:15498508 NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 decreases expression ISO tamibarotene results in decreased expression of ITPR3 mRNA CTD PMID:15498508 NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702 		JBrowse link
G Jak1 Janus kinase 1 affects expression ISO tamibarotene affects the expression of JAK1 mRNA CTD PMID:15498508 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904 		JBrowse link
G Jak3 Janus kinase 3 decreases expression ISO tamibarotene results in decreased expression of JAK3 mRNA CTD PMID:20861477 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668 		JBrowse link
G Kat5 lysine acetyltransferase 5 increases expression ISO tamibarotene results in increased expression of KAT5 mRNA CTD PMID:15498508 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597 		JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects expression ISO tamibarotene affects the expression of KCNAB2 mRNA CTD PMID:15498508 NCBI chr 5:169,570,327...169,658,875
Ensembl chr 5:169,572,517...169,658,875 		JBrowse link
G Kdm5b lysine demethylase 5B affects expression ISO tamibarotene affects the expression of KDM5B mRNA CTD PMID:15498508 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357 		JBrowse link
G Kif2a kinesin family member 2A decreases expression ISO tamibarotene results in decreased expression of KIF2A mRNA CTD PMID:15498508 NCBI chr 2:38,145,507...38,208,765
Ensembl chr 2:38,147,601...38,208,719 		JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression ISO tamibarotene results in decreased expression of KLF10 mRNA CTD PMID:15498508 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148 		JBrowse link
G Klf5 Kruppel-like factor 5 multiple interactions ISO tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [KLF5 protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [KLF5 results in increased expression of PDGFA mRNA] CTD PMID:16224062 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921 		JBrowse link
G Klf9 Kruppel-like factor 9 decreases expression ISO tamibarotene results in decreased expression of KLF9 mRNA CTD PMID:15498508 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198 		JBrowse link
G Kmt2b lysine methyltransferase 2B affects expression ISO tamibarotene affects the expression of KMT2B mRNA CTD PMID:15498508 NCBI chr 1:89,022,889...89,042,176
Ensembl chr 1:89,023,200...89,042,176 		JBrowse link
G Lamc1 laminin subunit gamma 1 decreases expression ISO tamibarotene results in decreased expression of LAMC1 mRNA CTD PMID:15498508 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515 		JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO tamibarotene results in increased expression of LASP1 mRNA CTD PMID:15498508 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of LCK mRNA CTD PMID:15498508 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO tamibarotene results in increased expression of LCP2 mRNA CTD PMID:15498508 NCBI chr10:18,996,523...19,043,289
Ensembl chr10:18,996,523...19,043,286 		JBrowse link
G Lgals1 galectin 1 increases expression ISO tamibarotene results in increased expression of LGALS1 mRNA CTD PMID:15498508 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289 		JBrowse link
G Lgals9 galectin 9 increases expression ISO tamibarotene results in increased expression of LGALS9 mRNA CTD PMID:15498508 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201 		JBrowse link
G Lmnb1 lamin B1 affects expression ISO tamibarotene affects the expression of LMNB1 mRNA CTD PMID:15498508 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264 		JBrowse link
G Lpin1 lipin 1 decreases expression ISO tamibarotene results in decreased expression of LPIN1 mRNA CTD PMID:15498508 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046 		JBrowse link
G Lrba LPS responsive beige-like anchor protein affects expression ISO tamibarotene affects the expression of LRBA mRNA CTD PMID:15498508 NCBI chr 2:185,590,983...186,110,491
Ensembl chr 2:185,524,774...186,110,495 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor decreases expression ISO tamibarotene results in decreased expression of LSM14A mRNA CTD PMID:15498508 NCBI chr 1:90,200,866...90,246,292
Ensembl chr 1:90,200,876...90,246,297 		JBrowse link
G Lsp1 lymphocyte-specific protein 1 increases expression ISO tamibarotene results in increased expression of LSP1 mRNA CTD PMID:15498508 NCBI chr 1:215,628,750...215,662,505
Ensembl chr 1:215,628,785...215,662,504 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO tamibarotene results in increased expression of LST1 mRNA CTD PMID:15498508 NCBI chr20:5,175,213...5,179,352
Ensembl chr20:5,176,016...5,179,263 		JBrowse link
G Ltb4r leukotriene B4 receptor affects expression ISO tamibarotene affects the expression of LTB4R mRNA CTD PMID:15498508 NCBI chr15:34,449,299...34,453,352
Ensembl chr15:34,452,116...34,453,171 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression ISO tamibarotene results in increased expression of LY6E mRNA CTD PMID:15498508 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of LYN mRNA CTD PMID:15498508 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Lztfl1 leucine zipper transcription factor-like 1 increases expression ISO tamibarotene results in increased expression of LZTFL1 mRNA CTD PMID:17229644 NCBI chr 8:132,774,393...132,790,922
Ensembl chr 8:132,775,587...132,790,839 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects expression ISO tamibarotene affects the expression of MACF1 mRNA CTD PMID:15498508 NCBI chr 5:141,039,455...141,363,524
Ensembl chr 5:141,039,468...141,363,524 		JBrowse link
G Macir macrophage immunometabolism regulator decreases expression ISO tamibarotene results in decreased expression of MACIR mRNA CTD PMID:15498508 NCBI chr 9:111,327,333...111,347,428
Ensembl chr 9:111,327,402...111,347,430 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 increases expression ISO tamibarotene results in increased expression of MAP4K1 mRNA CTD PMID:17229644 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 [tamibarotene co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; tamibarotene promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]
tamibarotene results in increased phosphorylation of MAPK1 protein
BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]		 CTD PMID:15020266 PMID:19457078 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression ISO tamibarotene affects the expression of MAPK14 mRNA CTD PMID:15498508 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 [tamibarotene co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; tamibarotene promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]
tamibarotene results in increased phosphorylation of MAPK3 protein
BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]		 CTD PMID:15020266 PMID:19457078 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression ISO tamibarotene results in increased expression of MAPKAPK2 mRNA CTD PMID:17229644 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110 		JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO tamibarotene results in decreased expression of MAT2A mRNA CTD PMID:15498508 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080 		JBrowse link
G Mbp myelin basic protein multiple interactions
increases expression		 EXP tamibarotene affects the reaction [MBP results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of IFNG mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of IL10 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of NOS2 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of TNF mRNA]
tamibarotene results in increased expression of MBP		 CTD PMID:11501064 PMID:19182380 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310 		JBrowse link
G Mdk midkine increases expression ISO tamibarotene results in increased expression of MDK mRNA CTD PMID:17229644 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Mdm1 Mdm1 nuclear protein decreases expression ISO tamibarotene results in decreased expression of MDM1 mRNA CTD PMID:15498508 NCBI chr 7:61,165,652...61,200,865
Ensembl chr 7:61,165,640...61,200,879 		JBrowse link
G Mdn1 midasin AAA ATPase 1 affects expression ISO tamibarotene affects the expression of MDN1 mRNA CTD PMID:15498508 NCBI chr 5:47,894,526...48,036,071
Ensembl chr 5:47,894,530...48,036,287 		JBrowse link
G Med21 mediator complex subunit 21 affects expression ISO tamibarotene affects the expression of MED21 mRNA CTD PMID:15498508 NCBI chr 4:180,961,194...180,968,155
Ensembl chr 4:180,961,142...180,968,123 		JBrowse link
G Mfap3 microfibril associated protein 3 affects expression ISO tamibarotene affects the expression of MFAP3 mRNA CTD PMID:15498508 NCBI chr10:42,933,077...42,945,591
Ensembl chr10:42,933,077...42,945,564 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression ISO tamibarotene results in increased expression of MFGE8 mRNA CTD PMID:17229644 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894 		JBrowse link
G Morc2 MORC family CW-type zinc finger 2 decreases expression ISO tamibarotene results in decreased expression of MORC2 mRNA CTD PMID:15498508 NCBI chr14:83,889,138...83,930,263
Ensembl chr14:83,889,089...83,930,522 		JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO tamibarotene results in decreased expression of MSH6 mRNA CTD PMID:15498508 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499 		JBrowse link
G Msi1 musashi RNA-binding protein 1 affects expression ISO tamibarotene affects the expression of MSI1 mRNA CTD PMID:15498508 NCBI chr12:46,899,835...46,935,335
Ensembl chr12:46,895,447...46,920,952 		JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:16484594 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052 		JBrowse link
G Mt1 metallothionein 1 increases expression ISO tamibarotene results in increased expression of MT1A mRNA CTD PMID:15498508 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724 		JBrowse link
G Mt3 metallothionein 3 affects expression ISO tamibarotene affects the expression of MT3 mRNA CTD PMID:15498508 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139 		JBrowse link
G Mta1 metastasis associated 1 decreases expression ISO tamibarotene results in decreased expression of MTA1 mRNA CTD PMID:15498508 NCBI chr 6:137,911,302...137,950,066
Ensembl chr 6:137,924,293...137,950,075 		JBrowse link
G Mtg1 mitochondrial ribosome-associated GTPase 1 affects expression ISO tamibarotene affects the expression of MTG1 mRNA CTD PMID:15498508 NCBI chr 1:212,606,753...212,619,493
Ensembl chr 1:212,606,777...212,619,493 		JBrowse link
G Mtmr6 myotubularin related protein 6 decreases expression ISO tamibarotene results in decreased expression of MTMR6 mRNA CTD PMID:15498508 NCBI chr15:40,558,917...40,597,311
Ensembl chr15:40,558,932...40,597,309 		JBrowse link
G Myb MYB proto-oncogene, transcription factor affects expression ISO tamibarotene affects the expression of MYB mRNA CTD PMID:15498508 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO tamibarotene results in decreased expression of MYC mRNA CTD PMID:15498508 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression ISO tamibarotene results in increased expression of MYD88 mRNA CTD PMID:15498508 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841 		JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 decreases expression ISO tamibarotene results in decreased expression of N4BP2L2 mRNA CTD PMID:15498508 NCBI chr12:627,128...650,604
Ensembl chr12:628,488...650,376 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO tamibarotene results in decreased expression of NAP1L1 mRNA CTD PMID:15498508 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 decreases expression ISO tamibarotene results in decreased expression of NCBP2 mRNA CTD PMID:15498508 NCBI chr11:72,071,838...72,103,087
Ensembl chr11:72,921,282...72,929,003 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression ISO tamibarotene results in increased expression of NCF1 mRNA CTD PMID:15498508 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300 		JBrowse link
G Nck1 NCK adaptor protein 1 affects expression ISO tamibarotene affects the expression of NCK1 mRNA CTD PMID:15498508 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 decreases expression ISO tamibarotene results in decreased expression of NCOA6 mRNA CTD PMID:15498508 NCBI chr 3:150,919,317...150,990,391
Ensembl chr 3:150,919,317...150,960,030 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 increases expression ISO tamibarotene results in increased expression of NCOR2 mRNA CTD PMID:17229644 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701 		JBrowse link
G Nemp1 nuclear envelope integral membrane protein 1 decreases expression ISO tamibarotene results in decreased expression of NEMP1 mRNA CTD PMID:15498508 NCBI chr 7:70,987,860...70,996,029
Ensembl chr 7:70,987,861...70,995,474 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression ISO tamibarotene results in increased expression of NFE2 mRNA CTD PMID:15498508 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression ISO tamibarotene results in decreased expression of NFE2L2 mRNA CTD PMID:15498508 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nfyb nuclear transcription factor Y subunit beta decreases expression ISO tamibarotene results in decreased expression of NFYB mRNA CTD PMID:15498508 NCBI chr 7:27,081,667...27,097,481
Ensembl chr 7:27,081,667...27,097,479 		JBrowse link
G Nipsnap1 nipsnap homolog 1 increases expression ISO tamibarotene results in increased expression of NIPSNAP1 mRNA CTD PMID:15498508 NCBI chr14:85,113,578...85,137,457
Ensembl chr14:85,113,578...85,137,454 		JBrowse link
G Nkg7 natural killer cell granule protein 7 increases expression ISO tamibarotene results in increased expression of NKG7 mRNA CTD PMID:15498508 NCBI chr 1:98,492,873...98,493,940
Ensembl chr 1:98,492,828...98,493,978 		JBrowse link
G Nkrf NFKB repressing factor increases expression ISO tamibarotene results in increased expression of NKRF mRNA CTD PMID:20861477 NCBI chr  X:123,502,074...123,516,301
Ensembl chr  X:123,502,096...123,515,720 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP tamibarotene inhibits the reaction [MBP results in increased expression of NOS2 mRNA] CTD PMID:11501064 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 increases expression ISO tamibarotene results in increased expression of NPC2 mRNA CTD PMID:15498508 NCBI chr 6:108,467,410...108,488,330
Ensembl chr 6:108,467,410...108,488,330 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity
multiple interactions		 ISO tamibarotene results in increased activity of NR1H4 protein
tamibarotene inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]		 CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 decreases expression ISO tamibarotene results in decreased expression of NR2F2 mRNA CTD PMID:15498508 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 [tamibarotene co-treated with BDNF] results in increased expression of NTRK2
tamibarotene results in increased expression of NTRK2
BDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein]		 CTD PMID:19182380 PMID:19457078 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676 		JBrowse link
G Nudt21 nudix hydrolase 21 affects expression ISO tamibarotene affects the expression of NUDT21 mRNA CTD PMID:15498508 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644 		JBrowse link
G Nutf2 nuclear transport factor 2 affects expression ISO tamibarotene affects the expression of NUTF2 mRNA CTD PMID:15498508 NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A affects expression ISO tamibarotene affects the expression of OAS1 mRNA CTD PMID:15498508 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO tamibarotene results in increased expression of OAS2 mRNA CTD PMID:15498508 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO tamibarotene results in increased expression of OASL mRNA CTD PMID:15498508 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894 		JBrowse link
G Ocln occludin increases expression ISO tamibarotene results in increased expression of OCLN mRNA CTD PMID:16982755 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO tamibarotene results in decreased expression of ODC1 mRNA CTD PMID:15498508 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927 		JBrowse link
G Oga O-GlcNAcase decreases expression ISO tamibarotene results in decreased expression of OGA mRNA CTD PMID:15498508 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression ISO tamibarotene results in increased expression of OGG1 mRNA CTD PMID:15498508 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO tamibarotene results in decreased expression of OGT mRNA CTD PMID:15498508 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908 		JBrowse link
G Orc2 origin recognition complex, subunit 2 decreases expression ISO tamibarotene results in decreased expression of ORC2 mRNA CTD PMID:15498508 NCBI chr 9:65,350,630...65,387,293
Ensembl chr 9:65,350,627...65,387,169 		JBrowse link
G P2rx5 purinergic receptor P2X 5 increases expression ISO tamibarotene results in increased expression of P2RX5 mRNA CTD PMID:17229644 NCBI chr10:59,725,438...59,737,126
Ensembl chr10:59,725,398...59,737,126 		JBrowse link
G P2ry14 purinergic receptor P2Y14 increases expression ISO tamibarotene results in increased expression of P2RY14 mRNA CTD PMID:15498508 NCBI chr 2:149,331,948...149,379,336
Ensembl chr 2:149,331,948...149,347,796 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 increases expression ISO tamibarotene results in increased expression of PAK1 mRNA CTD PMID:15498508 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 affects expression ISO tamibarotene affects the expression of PAK2 mRNA CTD PMID:15498508 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902 		JBrowse link
G Pank3 pantothenate kinase 3 affects expression ISO tamibarotene affects the expression of PANK3 mRNA CTD PMID:15498508 NCBI chr10:20,591,432...20,615,258
Ensembl chr10:20,591,432...20,615,258 		JBrowse link
G Papola poly (A) polymerase alpha affects expression ISO tamibarotene affects the expression of PAPOLA mRNA CTD PMID:15498508 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531 		JBrowse link
G Pcdh1 protocadherin 1 affects expression ISO tamibarotene affects the expression of PCDH1 mRNA CTD PMID:15498508 NCBI chr18:31,330,081...31,343,147
Ensembl chr18:31,328,919...31,343,797 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 affects expression ISO tamibarotene affects the expression of PCMT1 mRNA CTD PMID:15498508 NCBI chr 1:1,734,863...1,767,759
Ensembl chr 1:1,736,276...1,767,618 		JBrowse link
G Pcna proliferating cell nuclear antigen affects expression ISO tamibarotene affects the expression of PCNA mRNA CTD PMID:15498508 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [KLF5 results in increased expression of PDGFA mRNA]; tamibarotene inhibits the reaction [RARA protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [RXRA protein binds to PDGFA promoter] CTD PMID:16224062 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X affects expression ISO tamibarotene affects the expression of PDHX mRNA CTD PMID:15498508 NCBI chr 3:92,910,300...92,933,725
Ensembl chr 3:92,909,725...92,969,050 		JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO tamibarotene results in increased expression of PGD mRNA CTD PMID:15498508 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein decreases expression ISO tamibarotene results in decreased expression of PHYHIP mRNA CTD PMID:15498508 NCBI chr15:52,148,737...52,160,283
Ensembl chr15:52,767,442...52,778,687 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta affects expression ISO tamibarotene affects the expression of PIK3CB mRNA CTD PMID:15498508 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta increases expression ISO tamibarotene results in increased expression of PIK3CD mRNA CTD PMID:15498508 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of and results in increased activity of PIK3CG protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of PIK3CG mRNA]; tamibarotene results in increased expression of and results in increased activity of PIK3CG protein CTD PMID:15020266 PMID:15498508 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing decreases expression ISO tamibarotene results in decreased expression of PIKFYVE mRNA CTD PMID:15498508 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO tamibarotene results in increased expression of PIM1 mRNA CTD PMID:15498508 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555 		JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta affects expression ISO tamibarotene affects the expression of PITPNB mRNA CTD PMID:15498508 NCBI chr12:51,279,194...51,341,752
Ensembl chr12:51,280,150...51,341,716 		JBrowse link
G Pkn1 protein kinase N1 increases expression ISO tamibarotene results in increased expression of PKN1 mRNA CTD PMID:15498508 NCBI chr19:24,803,524...24,832,305
Ensembl chr19:24,803,524...24,831,500 		JBrowse link
G Pkp4 plakophilin 4 decreases expression ISO tamibarotene results in decreased expression of PKP4 mRNA CTD PMID:15498508 NCBI chr 3:45,211,097...45,414,524
Ensembl chr 3:45,277,348...45,414,613 		JBrowse link
G Plek pleckstrin increases expression ISO tamibarotene results in increased expression of PLEK mRNA CTD PMID:15498508 PMID:17229644 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913 		JBrowse link
G Plk4 polo-like kinase 4 decreases expression ISO tamibarotene results in decreased expression of PLK4 mRNA CTD PMID:15498508 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518 		JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO tamibarotene results in increased expression of PLSCR1 mRNA CTD PMID:15498508 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217 		JBrowse link
G Plxna1 plexin A1 increases expression ISO tamibarotene results in increased expression of PLXNA1 mRNA CTD PMID:17229644 NCBI chr 4:121,217,658...121,262,697
Ensembl chr 4:121,217,629...121,257,885 		JBrowse link
G Pnn pinin, desmosome associated protein decreases expression ISO tamibarotene results in decreased expression of PNN mRNA CTD PMID:15498508 NCBI chr 6:80,159,364...80,167,677
Ensembl chr 6:80,159,364...80,167,677 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO tamibarotene results in increased expression of POLD4 mRNA CTD PMID:15498508 NCBI chr 1:219,480,841...219,483,244
Ensembl chr 1:219,481,575...219,483,241 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO tamibarotene results in increased expression of POR mRNA CTD PMID:15498508 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase decreases expression ISO tamibarotene results in decreased expression of PPAT mRNA CTD PMID:15498508 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919 		JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 decreases expression ISO tamibarotene results in decreased expression of PPFIA1 mRNA CTD PMID:15498508 NCBI chr 1:217,644,259...217,721,285
Ensembl chr 1:217,644,224...217,721,376 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression ISO tamibarotene results in decreased expression of PPP1CB mRNA CTD PMID:15498508 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO tamibarotene results in increased expression of PPP1R15A mRNA CTD PMID:17229644 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta affects expression ISO tamibarotene affects the expression of PPP2R1B mRNA CTD PMID:15498508 NCBI chr 8:55,279,278...55,311,768
Ensembl chr 8:55,279,373...55,301,320 		JBrowse link
G Prdm2 PR/SET domain 2 affects expression ISO tamibarotene affects the expression of PRDM2 mRNA CTD PMID:15498508 NCBI chr 5:161,769,587...161,879,150
Ensembl chr 5:161,770,653...161,879,133 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression ISO tamibarotene results in increased expression of PRKACA mRNA CTD PMID:17229644 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta decreases expression ISO tamibarotene results in decreased expression of PRKACB mRNA CTD PMID:15498508 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886 		JBrowse link
G Prkcb protein kinase C, beta increases expression ISO tamibarotene results in increased expression of PRKCB mRNA CTD PMID:15498508 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831 		JBrowse link
G Prkcd protein kinase C, delta increases expression ISO tamibarotene results in increased expression of PRKCD mRNA CTD PMID:15498508 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
G Prkci protein kinase C, iota decreases expression ISO tamibarotene results in decreased expression of PRKCI mRNA CTD PMID:15498508 NCBI chr 2:115,941,998...116,002,550
Ensembl chr 2:115,941,993...116,002,561 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression
affects expression		 ISO tamibarotene results in decreased expression of PRKDC mRNA
tamibarotene affects the expression of PRKDC mRNA		 CTD PMID:15498508 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 increases expression ISO tamibarotene results in increased expression of PRMT2 mRNA CTD PMID:15498508 NCBI chr20:13,154,513...13,212,613
Ensembl chr20:13,156,241...13,212,606 		JBrowse link
G Prnp prion protein affects expression ISO tamibarotene affects the expression of PRNP mRNA CTD PMID:15498508 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316 		JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A affects expression ISO tamibarotene affects the expression of PRPF40A mRNA CTD PMID:15498508 NCBI chr 3:38,680,583...38,741,570
Ensembl chr 3:38,682,146...38,741,113 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 affects expression ISO tamibarotene affects the expression of PRPS1 mRNA CTD PMID:15498508 NCBI chr  X:111,798,233...111,820,270
Ensembl chr  X:111,798,233...111,820,266 		JBrowse link
G Prrc2c proline-rich coiled-coil 2C decreases expression ISO tamibarotene results in decreased expression of PRRC2C mRNA