CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: camphor
Accession: CHEBI:36773
browse the term
Definition: A cyclic monoterpene ketone that is bornane bearing an oxo substituent at position 2. A naturally occurring monoterpenoid.
Synonyms: exact_synonym: 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one; bornan-2-one
related_synonym: 2-bornanone; 2-camphanone; 2-keto-1,7,7-trimethylnorcamphane; Formosa camphor; Formula=C10H16O; InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3; InChIKey=DSSYKIVIOFKYAU-UHFFFAOYSA-N; Japan camphor; Kampfer; SMILES=CC1(C)C2CCC1(C)C(=O)C2; gum camphor; laurel camphor; root bark oil; spirit of camphor
xref: Beilstein:1907611; Beilstein:3196099; Beilstein:6475830; CAS:464-48-2; CAS:76-22-2; DrugBank:DB01744; Drug_Central:470; Gmelin:83275; KEGG:C00809; KEGG:C18369; KEGG:D00098; KNApSAcK:C00000135; LIPID_MAPS_instance:LMPR0102120001
xref_mesh: MESH:D002164
xref: MetaCyc:Camphor; PMID:17488023; PMID:19384733; PMID:20950270; PMID:21562741; PMID:21620923; PMID:21777420; PMID:21906366; Reaxys:3196099; Wikipedia:Camphor
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Col1a2
collagen type I alpha 2 chain
affects expression
ISO
Camphor analog affects the expression of COL1A2 mRNA
CTD
PMID:24704097
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases activity
EXP
Camphor results in decreased activity of CYP2B1 protein
CTD
PMID:9242356
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
multiple interactions
ISO
Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion]
CTD
PMID:18611395
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Esr1
estrogen receptor 1
multiple interactions
ISO
Camphor binds to and results in increased activity of ESR1 protein
CTD
PMID:27633901
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Mpo
myeloperoxidase
multiple interactions
ISO
Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein]
CTD
PMID:21466812
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
G
Pgr
progesterone receptor
multiple interactions
ISO
Camphor binds to and results in decreased activity of PGR protein
CTD
PMID:27633901
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Runx2
RUNX family transcription factor 2
affects expression
ISO
Camphor analog affects the expression of RUNX2 mRNA
CTD
PMID:24704097
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
G
Sparc
secreted protein acidic and cysteine rich
affects expression
ISO
Camphor analog affects the expression of SPARC mRNA
CTD
PMID:24704097
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein]
CTD
PMID:18172555
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
G
Trpv3
transient receptor potential cation channel, subfamily V, member 3
increases activity multiple interactions
ISO
Camphor results in increased activity of TRPV3 protein isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]
CTD
PMID:21353389
NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
G
Col1a2
collagen type I alpha 2 chain
affects expression
ISO
Camphor analog affects the expression of COL1A2 mRNA
CTD
PMID:24704097
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases activity
EXP
Camphor results in decreased activity of CYP2B1 protein
CTD
PMID:9242356
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
multiple interactions
ISO
Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion]
CTD
PMID:18611395
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Esr1
estrogen receptor 1
multiple interactions
ISO
Camphor binds to and results in increased activity of ESR1 protein
CTD
PMID:27633901
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
CTD
PMID:15588619
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Mpo
myeloperoxidase
multiple interactions
ISO
Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein]
CTD
PMID:21466812
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
G
Pgr
progesterone receptor
multiple interactions
ISO
Camphor binds to and results in decreased activity of PGR protein
CTD
PMID:27633901
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
G
Runx2
RUNX family transcription factor 2
affects expression
ISO
Camphor analog affects the expression of RUNX2 mRNA
CTD
PMID:24704097
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
G
Sparc
secreted protein acidic and cysteine rich
affects expression
ISO
Camphor analog affects the expression of SPARC mRNA
CTD
PMID:24704097
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein]
CTD
PMID:18172555
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
G
Trpv3
transient receptor potential cation channel, subfamily V, member 3
increases activity multiple interactions
ISO
Camphor results in increased activity of TRPV3 protein isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]
CTD
PMID:21353389
NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
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