Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:monochlorobiphenyl
go back to main search page
Accession:CHEBI:36717 term browser browse the term
Definition:A chlorobiphenyl carrying a single chloro substituent at unspecified position.
Synonyms:exact_synonym: chloro-1,1'-biphenyl
 related_synonym: Formula=C12H9Cl;   chlorobiphenyl;   chlorodiphenyl;   diphenylchloride
 xref: CAS:27323-18-8


show annotations for term's descendants           Sort by:
 
2-chlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 2-chlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO 2-chlorobiphenyl results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2-chlorobiphenyl analog results in increased activity of NR1I3 protein; 2-chlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
3-chlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 3-chlorobiphenyl analog results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
4-chlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO 4-chlorobiphenyl results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO 4-chlorobiphenyl metabolite results in increased expression of G6PD mRNA CTD PMID:25417049 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Hk2 hexokinase 2 increases expression ISO 4-chlorobiphenyl metabolite results in increased expression of HK2 mRNA CTD PMID:25417049 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases response to substance EXP MAPK1 protein modified form results in increased susceptibility to 4-chlorobiphenyl analog CTD PMID:19631230 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases response to substance EXP MAPK3 protein modified form results in increased susceptibility to 4-chlorobiphenyl analog CTD PMID:19631230 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO 4-chlorobiphenyl metabolite results in increased expression of PKM mRNA CTD PMID:25417049 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases oxidation
ISO [PTGS2 protein results in increased oxidation of 4-chlorobiphenyl metabolite] which results in increased chemical synthesis of Quinones CTD PMID:19105592 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C decreases expression ISO 4-chlorobiphenyl metabolite results in decreased expression of SDHC mRNA CTD PMID:25417049 NCBI chr13:89,498,047...89,518,979
Ensembl chr13:89,498,048...89,518,939
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D decreases expression ISO 4-chlorobiphenyl metabolite results in decreased expression of SDHD mRNA CTD PMID:25417049 NCBI chr 8:55,028,125...55,037,604
Ensembl chr 8:55,028,125...55,037,604
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
ISO 4-chlorobiphenyl metabolite results in decreased expression of and results in decreased activity of SOD2 protein
4-chlorobiphenyl metabolite results in decreased expression of SOD2 mRNA
CTD PMID:20163859 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of 4-chlorobiphenyl metabolite CTD PMID:23584369 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
affects binding
ISO 4-chlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]
4-chlorobiphenyl metabolite binds to SULT2A1 protein
CTD PMID:24508592 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Ttr transthyretin multiple interactions ISO 4-chlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein] CTD PMID:23584369 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      molecular entity 19808
        polyatomic entity 19721
          molecule 19545
            cyclic compound 19349
              ring assembly 7025
                biphenyls 5782
                  chlorobiphenyl 5558
                    monochlorobiphenyl 15
                      2-chlorobiphenyl 3
                      3-chlorobiphenyl 1
                      4-chlorobiphenyl + 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    main group molecular entity 19696
                      s-block molecular entity 19456
                        hydrogen molecular entity 19447
                          hydrides 18703
                            organic hydride 18265
                              organic fundamental parent 18265
                                hydrocarbon 17986
                                  halohydrocarbon 13958
                                    chlorohydrocarbon 8574
                                      chloroarene 5558
                                        chlorobiphenyl 5558
                                          monochlorobiphenyl 15
                                            2-chlorobiphenyl 3
                                            3-chlorobiphenyl 1
                                            4-chlorobiphenyl + 13
paths to the root