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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acyl chloride
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Accession:CHEBI:36687 term browser browse the term
Definition:A compound consisting of an acyl group bonded to chlorine.
Synonyms:related_synonym: acid chloride;   acyl chlorides


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benzoyl chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule increases expression ISO benzoyl chloride results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
dichloroacetyl chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of CASP3 mRNA] CTD PMID:32073640 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA; 2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein]
CTD PMID:32073640 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein]
2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA; 2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein
CTD PMID:32073640 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA; 2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein]
CTD PMID:32073640 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA; 2,2-dichloroacetyl chloride results in increased expression of NOS2 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 protein]
CTD PMID:32073640 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA protein]
2,2-dichloroacetyl chloride results in increased expression of RELA mRNA; 2,2-dichloroacetyl chloride results in increased expression of RELA protein; 2,2-dichloroacetyl chloride results in increased expression of RELA protein modified form
CTD PMID:32073640 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in increased expression of TNF mRNA; 2,2-dichloroacetyl chloride results in increased expression of TNF protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF protein]
CTD PMID:32073640 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
phosgene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 affects expression ISO Phosgene affects the expression of ADCY6 mRNA CTD PMID:16300373 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Adcy8 adenylate cyclase 8 affects expression ISO Phosgene affects the expression of ADCY8 mRNA CTD PMID:16300373 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
JBrowse link
G Adss adenylosuccinate synthase affects expression ISO Phosgene affects the expression of ADSS mRNA CTD PMID:16300373 NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 affects expression ISO Phosgene affects the expression of AKR1B8 mRNA CTD PMID:16300373 NCBI chr 4:62,997,241...63,009,815 JBrowse link
G Alb albumin affects expression ISO Phosgene affects the expression of ALB1 mRNA CTD PMID:16300373 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase affects expression ISO Phosgene affects the expression of NRP mRNA CTD PMID:16300373 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Anxa1 annexin A1 affects expression ISO Phosgene affects the expression of ANXA1 mRNA CTD PMID:16300373 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Aplnr apelin receptor affects expression ISO Phosgene affects the expression of APLNR mRNA CTD PMID:16300373 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Areg amphiregulin affects expression ISO Phosgene affects the expression of AREG mRNA CTD PMID:16300373 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg2 arginase 2 affects expression ISO Phosgene affects the expression of ARG2 mRNA CTD PMID:16300373 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arrb1 arrestin, beta 1 affects expression ISO Phosgene affects the expression of ARRB1 mRNA CTD PMID:16300373 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) affects expression ISO Phosgene affects the expression of ASNS mRNA CTD PMID:16300373 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 affects expression ISO Phosgene affects the expression of ATF3 mRNA CTD PMID:16300373 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H affects expression ISO Phosgene affects the expression of ATP6V1H mRNA CTD PMID:16300373 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
JBrowse link
G Axin2 axin 2 affects expression ISO Phosgene affects the expression of AXIN2 mRNA CTD PMID:16300373 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bcl10 BCL10, immune signaling adaptor affects expression ISO Phosgene affects the expression of BCL10 mRNA CTD PMID:16300373 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO Phosgene affects the expression of BHLHE40 mRNA CTD PMID:16300373 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Blvrb biliverdin reductase B affects expression ISO Phosgene affects the expression of BLVRB mRNA CTD PMID:16300373 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bmp6 bone morphogenetic protein 6 affects expression ISO Phosgene affects the expression of BMP6 mRNA CTD PMID:16300373 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Ca4 carbonic anhydrase 4 affects expression ISO Phosgene affects the expression of CAR4 mRNA CTD PMID:16300373 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Casp1 caspase 1 increases expression
multiple interactions
EXP Phosgene results in increased expression of CASP1 mRNA
NLRP3 protein promotes the reaction [Phosgene results in increased expression of and results in increased activity of CASP1 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of CASP1 mRNA]; Phosgene results in increased expression of and results in increased activity of CASP1 protein
CTD PMID:33012731 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cbr3 carbonyl reductase 3 affects expression ISO Phosgene affects the expression of CBR3 mRNA CTD PMID:16300373 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO Phosgene affects the expression of CCN1 mRNA CTD PMID:16300373 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO Phosgene affects the expression of CDKN1A mRNA CTD PMID:16300373 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression ISO Phosgene affects the expression of CDKN2C mRNA CTD PMID:16300373 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta affects expression ISO Phosgene affects the expression of CEBPD mRNA CTD PMID:16300373 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cers4 ceramide synthase 4 affects expression ISO Phosgene affects the expression of CERS4 mRNA CTD PMID:16300373 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828
JBrowse link
G Ch25h cholesterol 25-hydroxylase affects expression ISO Phosgene affects the expression of CH25H mRNA CTD PMID:16300373 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Cldn4 claudin 4 affects expression ISO Phosgene affects the expression of CLDN4 mRNA CTD PMID:16300373 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Csk C-terminal Src kinase affects expression ISO Phosgene affects the expression of CSK mRNA CTD PMID:16300373 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Cstb cystatin B affects expression ISO Phosgene affects the expression of CSTB mRNA CTD PMID:16300373 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Ctps1 CTP synthase 1 affects expression ISO Phosgene affects the expression of CTPS mRNA CTD PMID:16300373 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Cttn cortactin affects expression ISO Phosgene affects the expression of CTTN mRNA CTD PMID:16300373 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO Phosgene affects the expression of CXCR4 mRNA CTD PMID:16300373 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 affects expression ISO Phosgene affects the expression of CXCR5 mRNA CTD PMID:16300373 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
JBrowse link
G Cyp51 cytochrome P450, family 51 affects expression ISO Phosgene affects the expression of CYP51 mRNA CTD PMID:16300373 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Ddx39a DExD-box helicase 39A affects expression ISO Phosgene affects the expression of DDX39A mRNA CTD PMID:16300373 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 affects expression ISO Phosgene affects the expression of DNAJC2 mRNA CTD PMID:16300373 NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431
JBrowse link
G Edn1 endothelin 1 increases expression EXP Phosgene results in increased expression of EDN1 protein CTD PMID:18645720 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egr1 early growth response 1 affects expression ISO Phosgene affects the expression of EGR1 mRNA CTD PMID:16300373 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 affects expression ISO Phosgene affects the expression of EGR2 mRNA CTD PMID:16300373 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A affects expression ISO Phosgene affects the expression of EIF1A mRNA CTD PMID:16300373 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta affects expression ISO Phosgene affects the expression of EIF2S2 mRNA CTD PMID:16300373 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 affects expression ISO Phosgene affects the expression of EIF4G3 mRNA CTD PMID:16300373 NCBI chr 5:150,197,410...150,418,363
Ensembl chr 5:150,195,226...150,418,363
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 affects expression ISO Phosgene affects the expression of EIF5 mRNA CTD PMID:16300373
G Elk3 ETS transcription factor ELK3 affects expression ISO Phosgene affects the expression of ELK3 mRNA CTD PMID:16300373 NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 affects expression ISO Phosgene affects the expression of ELL2 mRNA CTD PMID:16300373 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Epha2 Eph receptor A2 affects expression ISO Phosgene affects the expression of EPHA2 mRNA CTD PMID:16300373 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Ereg epiregulin affects expression ISO Phosgene affects the expression of EREG mRNA CTD PMID:16300373 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Esd esterase D affects expression ISO Phosgene affects the expression of ESD mRNA CTD PMID:16300373 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
JBrowse link
G F3 coagulation factor III, tissue factor affects expression ISO Phosgene affects the expression of F3 mRNA CTD PMID:16300373 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fbln5 fibulin 5 affects expression ISO Phosgene affects the expression of FBLN5 mRNA CTD PMID:16300373 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression ISO Phosgene affects the expression of FDFT1 mRNA CTD PMID:16300373 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdx1 ferredoxin 1 affects expression ISO Phosgene affects the expression of FDX1 mRNA CTD PMID:16300373 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects expression ISO Phosgene affects the expression of FGFR4 mRNA CTD PMID:16300373 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression
affects expression
EXP
ISO
Phosgene results in decreased expression of FLT1 mRNA; Phosgene results in decreased expression of FLT1 protein
Phosgene affects the expression of FLT1 protein
CTD PMID:15256155 PMID:18645720 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression ISO Phosgene affects the expression of FMO1 mRNA CTD PMID:16300373 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 affects expression ISO Phosgene affects the expression of FMO5 mRNA CTD PMID:16300373 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO Phosgene affects the expression of FOS mRNA CTD PMID:16300373 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fzd2 frizzled class receptor 2 affects expression ISO Phosgene affects the expression of FZD2 mRNA CTD PMID:16300373 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma affects expression ISO Phosgene affects the expression of GADD45G mRNA CTD PMID:16300373 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 affects expression ISO Phosgene affects the expression of GALNT3 mRNA CTD PMID:16300373 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression ISO Phosgene affects the expression of GCLC mRNA CTD PMID:16300373 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression ISO Phosgene affects the expression of GCLM mRNA CTD PMID:16300373 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 affects expression ISO Phosgene affects the expression of GDF15 mRNA CTD PMID:16300373 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression ISO Phosgene affects the expression of GPX2 mRNA CTD PMID:16300373 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gtf2i general transcription factor II I affects expression ISO Phosgene affects the expression of GTF2I mRNA CTD PMID:16300373 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
JBrowse link
G Hdac5 histone deacetylase 5 affects expression ISO Phosgene affects the expression of HDAC5 mRNA CTD PMID:16300373 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Hip1 huntingtin interacting protein 1 affects expression ISO Phosgene affects the expression of HIP1 mRNA CTD PMID:16300373 NCBI chr12:21,133,319...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 affects expression ISO Phosgene affects the expression of HIPK2 mRNA CTD PMID:16300373 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 affects expression ISO Phosgene affects the expression of HMGCS1 mRNA CTD PMID:16300373 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
decreases activity
ISO Phosgene affects the expression of HMOX1 mRNA
Phosgene results in decreased activity of HMOX1 protein
CTD PMID:16300373 PMID:21945045 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer2 homer scaffold protein 2 affects expression ISO Phosgene affects the expression of HOMER2 mRNA CTD PMID:16300373 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Hoxa5 homeo box A5 affects expression ISO Phosgene affects the expression of HOXA5 mRNA CTD PMID:16300373 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression ISO Phosgene affects the expression of HSPA1A mRNA CTD PMID:16300373
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression ISO Phosgene affects the expression of HSPA9 mRNA CTD PMID:16300373 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Icam2 intercellular adhesion molecule 2 affects expression ISO Phosgene affects the expression of ICAM2 mRNA CTD PMID:16300373 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 affects expression ISO Phosgene affects the expression of IDI1 mRNA CTD PMID:16300373 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 affects expression ISO Phosgene affects the expression of IGFBP7 mRNA CTD PMID:16300373 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
JBrowse link
G Il10 interleukin 10 increases expression EXP Phosgene results in increased expression of IL10 protein CTD PMID:33012731 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions
EXP Phosgene results in increased expression of IL18 protein
NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL18 protein]
CTD PMID:33012731 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP Phosgene results in increased expression of IL1B protein
NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL1B protein]
CTD PMID:33012731 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma affects expression ISO Phosgene affects the expression of IL2RG mRNA CTD PMID:16300373 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression
EXP NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL33 protein] CTD PMID:33012731 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 increases expression EXP Phosgene results in increased expression of IL4 protein CTD PMID:33012731 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Irs1 insulin receptor substrate 1 affects expression ISO Phosgene affects the expression of IRS1 mRNA CTD PMID:16300373 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression ISO Phosgene affects the expression of JUNB mRNA CTD PMID:16300373 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jup junction plakoglobin affects expression ISO Phosgene affects the expression of JUP mRNA CTD PMID:16300373 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 affects expression ISO Phosgene affects the expression of KCNA3 mRNA CTD PMID:16300373 NCBI chr 2:194,632,360...194,633,937
Ensembl chr 2:194,632,196...194,650,138
JBrowse link
G Kdr kinase insert domain receptor affects expression
decreases expression
ISO
EXP
Phosgene affects the expression of KDR mRNA
Phosgene results in decreased expression of KDR mRNA; Phosgene results in decreased expression of KDR protein
CTD PMID:16300373 PMID:18645720 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO Phosgene affects the expression of KIT mRNA CTD PMID:16300373 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Klf5 Kruppel-like factor 5 affects expression ISO Phosgene affects the expression of KLF5 mRNA CTD PMID:16300373 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Krt18 keratin 18 affects expression ISO Phosgene affects the expression of KRT18 mRNA CTD PMID:16300373 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt19 keratin 19 affects expression ISO Phosgene affects the expression of KRT19 mRNA CTD PMID:16300373 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Krt8 keratin 8 affects expression ISO Phosgene affects the expression of KRT8 mRNA CTD PMID:16300373 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Ldlr low density lipoprotein receptor affects expression ISO Phosgene affects the expression of LDLR mRNA CTD PMID:16300373 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lgals3 galectin 3 affects expression ISO Phosgene affects the expression of LGALS3 mRNA CTD PMID:16300373 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor affects expression ISO Phosgene affects the expression of LITAF mRNA CTD PMID:16300373 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lrp2 LDL receptor related protein 2 affects expression ISO Phosgene affects the expression of LRP2 mRNA CTD PMID:16300373 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase affects expression ISO Phosgene affects the expression of LYN mRNA CTD PMID:16300373 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects expression ISO Phosgene affects the expression of MACF1 mRNA CTD PMID:16300373 NCBI chr 5:135,623,729...135,949,097
Ensembl chr 5:135,623,742...135,945,905
JBrowse link
G Maff MAF bZIP transcription factor F affects expression ISO Phosgene affects the expression of MAFF mRNA CTD PMID:16300373 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK1 protein] CTD PMID:21818760 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK3 protein] CTD PMID:21818760 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
EXP Phosgene results in increased phosphorylation of MAPK8 protein
ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein]
CTD PMID:21818760 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK9 protein] CTD PMID:21818760 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau affects expression ISO Phosgene affects the expression of MAPT mRNA CTD PMID:16300373 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 affects expression ISO Phosgene affects the expression of MBD1 mRNA CTD PMID:16300373 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554
JBrowse link
G Mef2c myocyte enhancer factor 2C affects expression ISO Phosgene affects the expression of MEF2C mRNA CTD PMID:16300373 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 protein]
Phosgene results in increased expression of MMP9 mRNA; Phosgene results in increased expression of MMP9 protein
CTD PMID:21941784 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrc2 mannose receptor, C type 2 affects expression ISO Phosgene affects the expression of MRC2 mRNA CTD PMID:16300373 NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856
JBrowse link
G Msn moesin affects expression ISO Phosgene affects the expression of MSN mRNA CTD PMID:16300373 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628
JBrowse link
G Mt1 metallothionein 1 affects expression ISO Phosgene affects the expression of MT1 mRNA CTD PMID:16300373 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A affects expression ISO Phosgene affects the expression of MT2 mRNA CTD PMID:16300373 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase affects expression ISO Phosgene affects the expression of MTHFD2 mRNA CTD PMID:16300373 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression ISO Phosgene affects the expression of MYC mRNA CTD PMID:16300373 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit affects expression ISO Phosgene affects the expression of NAA15 mRNA CTD PMID:16300373 NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 affects expression ISO Phosgene affects the expression of NCOR2 mRNA CTD PMID:16300373 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Nfix nuclear factor I X affects expression ISO Phosgene affects the expression of NFIX mRNA CTD PMID:16300373 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
JBrowse link
G Nisch nischarin affects expression ISO Phosgene affects the expression of NISCH mRNA CTD PMID:16300373 NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
EXP NLRP3 protein promotes the reaction [Phosgene results in increased expression of and results in increased activity of CASP1 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of CASP1 mRNA]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL33 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of TNF protein]
Phosgene results in increased expression of NLRP3 mRNA; Phosgene results in increased expression of NLRP3 protein
CTD PMID:33012731 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 affects response to substance
increases expression
multiple interactions
ISO
EXP
NOS2 affects the susceptibility to Phosgene
Phosgene results in increased expression of NOS2 protein
ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of NOS2 protein]
Phosgene results in increased expression of NOS2 mRNA; Phosgene results in increased expression of NOS2 protein
CTD PMID:21818760 PMID:25870319 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npnt nephronectin affects expression ISO Phosgene affects the expression of NPNT mRNA CTD PMID:16300373 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
JBrowse link
G Npr2 natriuretic peptide receptor 2 affects expression ISO Phosgene affects the expression of NPR2 mRNA CTD PMID:16300373 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Phosgene affects the expression of NR3C1 mRNA CTD PMID:16300373 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Orc5 origin recognition complex, subunit 5 affects expression ISO Phosgene affects the expression of ORC5 mRNA CTD PMID:16300373 NCBI chr 4:12,548,007...12,612,611
Ensembl chr 4:12,548,007...12,612,568
JBrowse link
G Osmr oncostatin M receptor affects expression ISO Phosgene affects the expression of OSMR mRNA CTD PMID:16300373 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
JBrowse link
G Pdgfb platelet derived growth factor subunit B affects expression ISO Phosgene affects the expression of PDGFB mRNA CTD PMID:16300373 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression ISO Phosgene affects the expression of PDK4 mRNA CTD PMID:16300373 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pgd phosphogluconate dehydrogenase affects expression ISO Phosgene affects the expression of PGD mRNA CTD PMID:16300373 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pla2g2a phospholipase A2 group IIA increases activity EXP Phosgene results in increased activity of PLA2G2A protein CTD PMID:19235614 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression ISO Phosgene affects the expression of PLAUR mRNA CTD PMID:16300373 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 affects expression ISO Phosgene affects the expression of PLOD2 mRNA CTD PMID:16300373 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Pltp phospholipid transfer protein affects expression ISO Phosgene affects the expression of PLTP mRNA CTD PMID:16300373 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Prdm1 PR/SET domain 1 affects expression ISO Phosgene affects the expression of PRDM1 mRNA CTD PMID:16300373 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prx periaxin affects expression ISO Phosgene affects the expression of PRX mRNA CTD PMID:16300373 NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:82,786,815...82,807,407
JBrowse link
G Ptger1 prostaglandin E receptor 1 affects expression ISO Phosgene affects the expression of PTGER1 mRNA CTD PMID:16300373 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression ISO Phosgene affects the expression of PTGS1 mRNA CTD PMID:16300373 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP
ISO
Phosgene results in increased expression of PTGS2 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]
CTD PMID:21818760 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 affects expression ISO Phosgene affects the expression of PTK2 mRNA CTD PMID:16300373 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pycard PYD and CARD domain containing increases expression EXP Phosgene results in increased expression of PYCARD mRNA; Phosgene results in increased expression of PYCARD protein CTD PMID:33012731 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rdh11 retinol dehydrogenase 11 affects expression ISO Phosgene affects the expression of RDH11 mRNA CTD PMID:16300373 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Rgs16 regulator of G-protein signaling 16 affects expression ISO Phosgene affects the expression of RGS16 mRNA CTD PMID:16300373 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rin1 Ras and Rab interactor 1 affects expression ISO Phosgene affects the expression of RIN1 mRNA CTD PMID:16300373 NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 affects expression ISO Phosgene affects the expression of RPS6KA2 mRNA CTD PMID:16300373 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
G S100a14 S100 calcium binding protein A14 affects expression ISO Phosgene affects the expression of S100A14 mRNA CTD PMID:16300373 NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423
JBrowse link
G Sars1 seryl-tRNA synthetase 1 affects expression ISO Phosgene affects the expression of SARS mRNA CTD PMID:16300373 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects expression ISO Phosgene affects the expression of SAT1 mRNA CTD PMID:16300373 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sema3b semaphorin 3B affects expression ISO Phosgene affects the expression of SEMA3B mRNA CTD PMID:16300373 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N affects expression ISO Phosgene affects the expression of SERPINA3N mRNA CTD PMID:16300373 NCBI chr 6:123,323,632...123,331,166 JBrowse link
G Serpine1 serpin family E member 1 affects expression ISO Phosgene affects the expression of SERPINE1 mRNA CTD PMID:16300373 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 affects expression ISO Phosgene affects the expression of SERPINE2 mRNA CTD PMID:16300373 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sftpb surfactant protein B multiple interactions ISO [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with Phosgene] results in increased expression of SFTPB mRNA CTD PMID:25870319 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression ISO Phosgene affects the expression of SHANK3 mRNA CTD PMID:16300373 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 affects expression ISO Phosgene affects the expression of SIPA1 mRNA CTD PMID:16300373 NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591
JBrowse link
G Slc3a2 solute carrier family 3 member 2 affects expression ISO Phosgene affects the expression of SLC3A2 mRNA CTD PMID:16300373 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc7a10 solute carrier family 7 member 10 affects expression ISO Phosgene affects the expression of SLC7A10 mRNA CTD PMID:16300373 NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071
JBrowse link
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 affects expression ISO Phosgene affects the expression of SMARCE1 mRNA CTD PMID:16300373 NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989
JBrowse link
G Sod2 superoxide dismutase 2 affects expression ISO Phosgene affects the expression of SOD2 mRNA CTD PMID:16300373 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 affects expression ISO Phosgene affects the expression of SOD3 mRNA CTD PMID:16300373 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sort1 sortilin 1 affects expression ISO Phosgene affects the expression of SORT1 mRNA CTD PMID:16300373 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sox18 SRY-box transcription factor 18 affects expression ISO Phosgene affects the expression of SOX18 mRNA CTD PMID:16300373 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
JBrowse link
G Sox4 SRY-box transcription factor 4 affects expression ISO Phosgene affects the expression of SOX4 mRNA CTD PMID:16300373 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Sphk1 sphingosine kinase 1 affects expression ISO Phosgene affects the expression of SPHK1 mRNA CTD PMID:16300373 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 affects expression ISO Phosgene affects the expression of SPOCK2 mRNA CTD PMID:16300373 NCBI chr20:28,036,909...28,064,272
Ensembl chr20:28,033,475...28,064,272
JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 affects expression ISO Phosgene affects the expression of ST3GAL2 mRNA CTD PMID:16300373 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
JBrowse link
G Stab1 stabilin 1 affects expression ISO Phosgene affects the expression of STAB1 mRNA CTD PMID:16300373 NCBI chr16:6,330,435...6,360,934
Ensembl chr16:6,330,444...6,360,923
JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 affects expression ISO Phosgene affects the expression of STARD13 mRNA CTD PMID:16300373 NCBI chr12:566,282...959,372
Ensembl chr12:566,310...959,421
JBrowse link
G Tbx2 T-box transcription factor 2 affects expression ISO Phosgene affects the expression of TBX2 mRNA CTD PMID:16300373 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Tek TEK receptor tyrosine kinase affects expression ISO Phosgene affects the expression of TEK mRNA CTD PMID:16300373 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Thbs1 thrombospondin 1 affects expression ISO Phosgene affects the expression of THBS1 mRNA CTD PMID:16300373 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 affects expression ISO Phosgene affects the expression of TIE1 mRNA CTD PMID:16300373 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Phosgene affects the expression of TIMP1 mRNA CTD PMID:16300373 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
ISO N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Phosgene results in decreased expression of TJP1 mRNA] CTD PMID:25870319 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP Phosgene results in increased expression of TNF protein
NLRP3 protein promotes the reaction [Phosgene results in increased expression of TNF protein]
CTD PMID:33012731 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A affects expression ISO Phosgene affects the expression of TNFRSF12A mRNA CTD PMID:16300373 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tpra1 transmembrane protein adipocyte associated 1 affects expression ISO Phosgene affects the expression of TPRA1 mRNA CTD PMID:16300373 NCBI chr 4:121,364,093...121,375,275
Ensembl chr 4:121,364,091...121,375,269
JBrowse link
G Tspo translocator protein affects expression ISO Phosgene affects the expression of TSPO mRNA CTD PMID:16300373 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Tuba1c tubulin, alpha 1C affects expression ISO Phosgene affects the expression of TUBA1C mRNA CTD PMID:16300373 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression ISO Phosgene affects the expression of TXNL1 mRNA CTD PMID:16300373 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
JBrowse link
G Txnrd1 thioredoxin reductase 1 affects expression ISO Phosgene affects the expression of TXNRD1 mRNA CTD PMID:16300373 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
ISO
EXP
Phosgene results in decreased expression of VEGFA mRNA; Phosgene results in decreased expression of VEGFA protein
Phosgene results in increased expression of VEGFA mRNA alternative form
CTD PMID:15256155 PMID:18645720 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 affects expression ISO Phosgene affects the expression of WRNIP1 mRNA CTD PMID:16300373 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19808
      group 19729
        polyatomic entity 19728
          heteroatomic molecular entity 19669
            halide 18136
              acyl halide 199
                acyl chloride 188
                  2-chlorobenzoyl chloride 0
                  4-chlorobenzoyl chloride 0
                  5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate 0
                  acetyl chloride 0
                  benzoyl chloride 1
                  dichloroacetyl chloride 7
                  pentafluorobenzoyl chloride 0
                  phosgene 183
                  trifluoroacetyl chloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            heteroorganic entity 19280
                              organohalogen compound 17913
                                organochlorine compound 17730
                                  acyl chloride 188
                                    2-chlorobenzoyl chloride 0
                                    4-chlorobenzoyl chloride 0
                                    5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate 0
                                    acetyl chloride 0
                                    benzoyl chloride 1
                                    dichloroacetyl chloride 7
                                    pentafluorobenzoyl chloride 0
                                    phosgene 183
                                    trifluoroacetyl chloride 0
paths to the root