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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acyl chloride
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Accession:CHEBI:36687 term browser browse the term
Definition:A compound consisting of an acyl group bonded to chlorine.
Synonyms:related_synonym: acid chloride;   acyl chlorides


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benzoyl chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule increases expression ISO benzoyl chloride results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
dichloroacetyl chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of CASP3 mRNA] CTD PMID:32073640 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA; 2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of HMOX1 protein]
CTD PMID:32073640 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein]
2,2-dichloroacetyl chloride results in increased expression of KEAP1 mRNA; 2,2-dichloroacetyl chloride results in increased expression of KEAP1 protein
CTD PMID:32073640 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA; 2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NFE2L2 protein]
CTD PMID:32073640 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA; 2,2-dichloroacetyl chloride results in increased expression of NOS2 protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of NOS2 protein]
CTD PMID:32073640 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of RELA protein]
2,2-dichloroacetyl chloride results in increased expression of RELA mRNA; 2,2-dichloroacetyl chloride results in increased expression of RELA protein; 2,2-dichloroacetyl chloride results in increased expression of RELA protein modified form
CTD PMID:32073640 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO 2,2-dichloroacetyl chloride results in increased expression of TNF mRNA; 2,2-dichloroacetyl chloride results in increased expression of TNF protein
2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF mRNA]; 2-tert-butylhydroquinone inhibits the reaction [2,2-dichloroacetyl chloride results in increased expression of TNF protein]
CTD PMID:32073640 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
phosgene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 affects expression ISO Phosgene affects the expression of ADCY6 mRNA CTD PMID:16300373 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Adcy8 adenylate cyclase 8 affects expression ISO Phosgene affects the expression of ADCY8 mRNA CTD PMID:16300373 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Adss adenylosuccinate synthase affects expression ISO Phosgene affects the expression of ADSS mRNA CTD PMID:16300373 NCBI chr13:95,913,426...95,943,761
Ensembl chr13:95,913,426...95,943,761
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 affects expression ISO Phosgene affects the expression of AKR1B8 mRNA CTD PMID:16300373 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Alb albumin affects expression ISO Phosgene affects the expression of ALB1 mRNA CTD PMID:16300373 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase affects expression ISO Phosgene affects the expression of NRP mRNA CTD PMID:16300373 NCBI chr 6:111,456,096...111,476,829
Ensembl chr 6:111,456,187...111,477,090
JBrowse link
G Anxa1 annexin A1 affects expression ISO Phosgene affects the expression of ANXA1 mRNA CTD PMID:16300373 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Aplnr apelin receptor affects expression ISO Phosgene affects the expression of APLNR mRNA CTD PMID:16300373 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Areg amphiregulin affects expression ISO Phosgene affects the expression of AREG mRNA CTD PMID:16300373 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg2 arginase 2 affects expression ISO Phosgene affects the expression of ARG2 mRNA CTD PMID:16300373 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arrb1 arrestin, beta 1 affects expression ISO Phosgene affects the expression of ARRB1 mRNA CTD PMID:16300373 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) affects expression ISO Phosgene affects the expression of ASNS mRNA CTD PMID:16300373 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf3 activating transcription factor 3 affects expression ISO Phosgene affects the expression of ATF3 mRNA CTD PMID:16300373 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H affects expression ISO Phosgene affects the expression of ATP6V1H mRNA CTD PMID:16300373 NCBI chr 5:14,262,352...14,367,898
Ensembl chr 5:14,262,349...14,367,898
JBrowse link
G Axin2 axin 2 affects expression ISO Phosgene affects the expression of AXIN2 mRNA CTD PMID:16300373 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bcl10 BCL10, immune signaling adaptor affects expression ISO Phosgene affects the expression of BCL10 mRNA CTD PMID:16300373 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO Phosgene affects the expression of BHLHE40 mRNA CTD PMID:16300373 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Blvrb biliverdin reductase B affects expression ISO Phosgene affects the expression of BLVRB mRNA CTD PMID:16300373 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bmp6 bone morphogenetic protein 6 affects expression ISO Phosgene affects the expression of BMP6 mRNA CTD PMID:16300373 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Ca4 carbonic anhydrase 4 affects expression ISO Phosgene affects the expression of CAR4 mRNA CTD PMID:16300373 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cbr3 carbonyl reductase 3 affects expression ISO Phosgene affects the expression of CBR3 mRNA CTD PMID:16300373 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO Phosgene affects the expression of CCN1 mRNA CTD PMID:16300373 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO Phosgene affects the expression of CDKN1A mRNA CTD PMID:16300373 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression ISO Phosgene affects the expression of CDKN2C mRNA CTD PMID:16300373 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta affects expression ISO Phosgene affects the expression of CEBPD mRNA CTD PMID:16300373 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cers4 ceramide synthase 4 affects expression ISO Phosgene affects the expression of CERS4 mRNA CTD PMID:16300373 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729
JBrowse link
G Ch25h cholesterol 25-hydroxylase affects expression ISO Phosgene affects the expression of CH25H mRNA CTD PMID:16300373 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Cldn4 claudin 4 affects expression ISO Phosgene affects the expression of CLDN4 mRNA CTD PMID:16300373 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Csk C-terminal Src kinase affects expression ISO Phosgene affects the expression of CSK mRNA CTD PMID:16300373 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Cstb cystatin B affects expression ISO Phosgene affects the expression of CSTB mRNA CTD PMID:16300373 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctps1 CTP synthase 1 affects expression ISO Phosgene affects the expression of CTPS mRNA CTD PMID:16300373 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Cttn cortactin affects expression ISO Phosgene affects the expression of CTTN mRNA CTD PMID:16300373 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO Phosgene affects the expression of CXCR4 mRNA CTD PMID:16300373 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 affects expression ISO Phosgene affects the expression of CXCR5 mRNA CTD PMID:16300373 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Cyp51 cytochrome P450, family 51 affects expression ISO Phosgene affects the expression of CYP51 mRNA CTD PMID:16300373 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Ddx39a DExD-box helicase 39A affects expression ISO Phosgene affects the expression of DDX39A mRNA CTD PMID:16300373 NCBI chr19:24,846,530...24,854,886
Ensembl chr19:24,846,938...24,854,953
JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 affects expression ISO Phosgene affects the expression of DNAJC2 mRNA CTD PMID:16300373 NCBI chr 4:9,881,505...9,908,693
Ensembl chr 4:9,882,904...9,908,689
JBrowse link
G Edn1 endothelin 1 increases expression EXP Phosgene results in increased expression of EDN1 protein CTD PMID:18645720 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 affects expression ISO Phosgene affects the expression of EGR1 mRNA CTD PMID:16300373 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 affects expression ISO Phosgene affects the expression of EGR2 mRNA CTD PMID:16300373 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A affects expression ISO Phosgene affects the expression of EIF1A mRNA CTD PMID:16300373 NCBI chr18:40,586,315...40,598,661
Ensembl chr18:40,586,315...40,597,671
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta affects expression ISO Phosgene affects the expression of EIF2S2 mRNA CTD PMID:16300373 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 affects expression ISO Phosgene affects the expression of EIF4G3 mRNA CTD PMID:16300373 NCBI chr 5:156,343,663...156,564,037
Ensembl chr 5:156,396,695...156,564,037
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 affects expression ISO Phosgene affects the expression of EIF5 mRNA CTD PMID:16300373 NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
JBrowse link
G Elk3 ETS transcription factor ELK3 affects expression ISO Phosgene affects the expression of ELK3 mRNA CTD PMID:16300373 NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 affects expression ISO Phosgene affects the expression of ELL2 mRNA CTD PMID:16300373 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Epha2 Eph receptor A2 affects expression ISO Phosgene affects the expression of EPHA2 mRNA CTD PMID:16300373 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Ereg epiregulin affects expression ISO Phosgene affects the expression of EREG mRNA CTD PMID:16300373 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Esd esterase D affects expression ISO Phosgene affects the expression of ESD mRNA CTD PMID:16300373 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G F3 coagulation factor III, tissue factor affects expression ISO Phosgene affects the expression of F3 mRNA CTD PMID:16300373 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fbln5 fibulin 5 affects expression ISO Phosgene affects the expression of FBLN5 mRNA CTD PMID:16300373 NCBI chr 6:125,644,797...125,723,957
Ensembl chr 6:125,644,804...125,723,944
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression ISO Phosgene affects the expression of FDFT1 mRNA CTD PMID:16300373 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdx1 ferredoxin 1 affects expression ISO Phosgene affects the expression of FDX1 mRNA CTD PMID:16300373 NCBI chr 8:56,373,729...56,393,199
Ensembl chr 8:56,373,723...56,393,233
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects expression ISO Phosgene affects the expression of FGFR4 mRNA CTD PMID:16300373 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression
affects expression
EXP
ISO
Phosgene results in decreased expression of FLT1 mRNA; Phosgene results in decreased expression of FLT1 protein
Phosgene affects the expression of FLT1 protein
CTD PMID:15256155, PMID:18645720 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression ISO Phosgene affects the expression of FMO1 mRNA CTD PMID:16300373 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 affects expression ISO Phosgene affects the expression of FMO5 mRNA CTD PMID:16300373 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO Phosgene affects the expression of FOS mRNA CTD PMID:16300373 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fzd2 frizzled class receptor 2 affects expression ISO Phosgene affects the expression of FZD2 mRNA CTD PMID:16300373 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma affects expression ISO Phosgene affects the expression of GADD45G mRNA CTD PMID:16300373 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 affects expression ISO Phosgene affects the expression of GALNT3 mRNA CTD PMID:16300373 NCBI chr 3:52,174,469...52,212,395
Ensembl chr 3:52,175,547...52,212,412
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression ISO Phosgene affects the expression of GCLC mRNA CTD PMID:16300373 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression ISO Phosgene affects the expression of GCLM mRNA CTD PMID:16300373 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 affects expression ISO Phosgene affects the expression of GDF15 mRNA CTD PMID:16300373 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression ISO Phosgene affects the expression of GPX2 mRNA CTD PMID:16300373 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gtf2i general transcription factor II I affects expression ISO Phosgene affects the expression of GTF2I mRNA CTD PMID:16300373 NCBI chr12:25,410,804...25,487,970
Ensembl chr12:25,411,207...25,488,156
JBrowse link
G Hdac5 histone deacetylase 5 affects expression ISO Phosgene affects the expression of HDAC5 mRNA CTD PMID:16300373 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hip1 huntingtin interacting protein 1 affects expression ISO Phosgene affects the expression of HIP1 mRNA CTD PMID:16300373 NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 affects expression ISO Phosgene affects the expression of HIPK2 mRNA CTD PMID:16300373 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 affects expression ISO Phosgene affects the expression of HMGCS1 mRNA CTD PMID:16300373 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
decreases activity
ISO Phosgene affects the expression of HMOX1 mRNA
Phosgene results in decreased activity of HMOX1 protein
CTD PMID:16300373, PMID:21945045 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Homer2 homer scaffold protein 2 affects expression ISO Phosgene affects the expression of HOMER2 mRNA CTD PMID:16300373 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Hoxa5 homeo box A5 affects expression ISO Phosgene affects the expression of HOXA5 mRNA CTD PMID:16300373
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression ISO Phosgene affects the expression of HSPA1A mRNA CTD PMID:16300373 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression ISO Phosgene affects the expression of HSPA9 mRNA CTD PMID:16300373 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Icam2 intercellular adhesion molecule 2 affects expression ISO Phosgene affects the expression of ICAM2 mRNA CTD PMID:16300373 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 affects expression ISO Phosgene affects the expression of IDI1 mRNA CTD PMID:16300373 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 affects expression ISO Phosgene affects the expression of IGFBP7 mRNA CTD PMID:16300373 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma affects expression ISO Phosgene affects the expression of IL2RG mRNA CTD PMID:16300373 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865
JBrowse link
G Irs1 insulin receptor substrate 1 affects expression ISO Phosgene affects the expression of IRS1 mRNA CTD PMID:16300373 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression ISO Phosgene affects the expression of JUNB mRNA CTD PMID:16300373 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jup junction plakoglobin affects expression ISO Phosgene affects the expression of JUP mRNA CTD PMID:16300373 NCBI chr10:88,280,517...88,307,451
Ensembl chr10:88,279,632...88,307,412
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 affects expression ISO Phosgene affects the expression of KCNA3 mRNA CTD PMID:16300373 NCBI chr 2:209,766,767...209,768,344
Ensembl chr 2:209,766,512...209,769,711
JBrowse link
G Kdr kinase insert domain receptor affects expression
decreases expression
ISO
EXP
Phosgene affects the expression of KDR mRNA
Phosgene results in decreased expression of KDR mRNA; Phosgene results in decreased expression of KDR protein
CTD PMID:16300373, PMID:18645720 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO Phosgene affects the expression of KIT mRNA CTD PMID:16300373 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klf5 Kruppel-like factor 5 affects expression ISO Phosgene affects the expression of KLF5 mRNA CTD PMID:16300373 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Krt18 keratin 18 affects expression ISO Phosgene affects the expression of KRT18 mRNA CTD PMID:16300373 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt19 keratin 19 affects expression ISO Phosgene affects the expression of KRT19 mRNA CTD PMID:16300373 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt8 keratin 8 affects expression ISO Phosgene affects the expression of KRT8 mRNA CTD PMID:16300373 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Ldlr low density lipoprotein receptor affects expression ISO Phosgene affects the expression of LDLR mRNA CTD PMID:16300373 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lgals3 galectin 3 affects expression ISO Phosgene affects the expression of LGALS3 mRNA CTD PMID:16300373 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor affects expression ISO Phosgene affects the expression of LITAF mRNA CTD PMID:16300373 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lrp2 LDL receptor related protein 2 affects expression ISO Phosgene affects the expression of LRP2 mRNA CTD PMID:16300373 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase affects expression ISO Phosgene affects the expression of LYN mRNA CTD PMID:16300373 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects expression ISO Phosgene affects the expression of MACF1 mRNA CTD PMID:16300373 NCBI chr 5:141,039,455...141,363,524
Ensembl chr 5:141,039,468...141,363,524
JBrowse link
G Maff MAF bZIP transcription factor F affects expression ISO Phosgene affects the expression of MAFF mRNA CTD PMID:16300373 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK1 protein] CTD PMID:21818760 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK3 protein] CTD PMID:21818760 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
EXP Phosgene results in increased phosphorylation of MAPK8 protein
ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein]
CTD PMID:21818760 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK9 protein] CTD PMID:21818760 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau affects expression ISO Phosgene affects the expression of MAPT mRNA CTD PMID:16300373 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 affects expression ISO Phosgene affects the expression of MBD1 mRNA CTD PMID:16300373 NCBI chr18:70,248,568...70,263,190
Ensembl chr18:70,248,713...70,263,164
JBrowse link
G Mef2c myocyte enhancer factor 2C affects expression ISO Phosgene affects the expression of MEF2C mRNA CTD PMID:16300373 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 protein]
Phosgene results in increased expression of MMP9 mRNA; Phosgene results in increased expression of MMP9 protein
CTD PMID:21941784 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrc2 mannose receptor, C type 2 affects expression ISO Phosgene affects the expression of MRC2 mRNA CTD PMID:16300373 NCBI chr10:93,520,272...93,581,599
Ensembl chr10:93,520,132...93,581,296
JBrowse link
G Msn moesin affects expression ISO Phosgene affects the expression of MSN mRNA CTD PMID:16300373 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Mt1 metallothionein 1 affects expression ISO Phosgene affects the expression of MT1 mRNA CTD PMID:16300373 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A affects expression ISO Phosgene affects the expression of MT2 mRNA CTD PMID:16300373 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase affects expression ISO Phosgene affects the expression of MTHFD2 mRNA CTD PMID:16300373 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression ISO Phosgene affects the expression of MYC mRNA CTD PMID:16300373 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit affects expression ISO Phosgene affects the expression of NAA15 mRNA CTD PMID:16300373 NCBI chr 2:140,471,437...140,534,259
Ensembl chr 2:140,471,690...140,534,259
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 affects expression ISO Phosgene affects the expression of NCOR2 mRNA CTD PMID:16300373 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Nfix nuclear factor I X affects expression ISO Phosgene affects the expression of NFIX mRNA CTD PMID:16300373 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nisch nischarin affects expression ISO Phosgene affects the expression of NISCH mRNA CTD PMID:16300373 NCBI chr16:7,254,372...7,290,670
Ensembl chr16:7,254,974...7,290,561
JBrowse link
G Nos2 nitric oxide synthase 2 affects response to substance
increases expression
multiple interactions
ISO
EXP
NOS2 affects the susceptibility to Phosgene
Phosgene results in increased expression of NOS2 protein
ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of NOS2 protein]
Phosgene results in increased expression of NOS2 mRNA; Phosgene results in increased expression of NOS2 protein
CTD PMID:21818760, PMID:25870319 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npnt nephronectin affects expression ISO Phosgene affects the expression of NPNT mRNA CTD PMID:16300373 NCBI chr 2:238,001,767...238,068,886
Ensembl chr 2:238,002,990...238,068,694
JBrowse link
G Npr2 natriuretic peptide receptor 2 affects expression ISO Phosgene affects the expression of NPR2 mRNA CTD PMID:16300373 NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Phosgene affects the expression of NR3C1 mRNA CTD PMID:16300373 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Orc5 origin recognition complex, subunit 5 affects expression ISO Phosgene affects the expression of ORC5 mRNA CTD PMID:16300373 NCBI chr 4:9,160,050...9,223,998
Ensembl chr 4:9,160,067...9,223,997
JBrowse link
G Osmr oncostatin M receptor affects expression ISO Phosgene affects the expression of OSMR mRNA CTD PMID:16300373 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
JBrowse link
G Pdgfb platelet derived growth factor subunit B affects expression ISO Phosgene affects the expression of PDGFB mRNA CTD PMID:16300373 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression ISO Phosgene affects the expression of PDK4 mRNA CTD PMID:16300373 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pgd phosphogluconate dehydrogenase affects expression ISO Phosgene affects the expression of PGD mRNA CTD PMID:16300373 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pla2g2a phospholipase A2 group IIA increases activity EXP Phosgene results in increased activity of PLA2G2A protein CTD PMID:19235614 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression ISO Phosgene affects the expression of PLAUR mRNA CTD PMID:16300373 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 affects expression ISO Phosgene affects the expression of PLOD2 mRNA CTD PMID:16300373 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Pltp phospholipid transfer protein affects expression ISO Phosgene affects the expression of PLTP mRNA CTD PMID:16300373 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Prdm1 PR/SET domain 1 affects expression ISO Phosgene affects the expression of PRDM1 mRNA CTD PMID:16300373 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prx periaxin affects expression ISO Phosgene affects the expression of PRX mRNA CTD PMID:16300373 NCBI chr 1:84,302,074...84,324,560
Ensembl chr 1:84,304,228...84,324,560
JBrowse link
G Ptger1 prostaglandin E receptor 1 affects expression ISO Phosgene affects the expression of PTGER1 mRNA CTD PMID:16300373 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression ISO Phosgene affects the expression of PTGS1 mRNA CTD PMID:16300373 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP
ISO
Phosgene results in increased expression of PTGS2 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]
CTD PMID:21818760 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 affects expression ISO Phosgene affects the expression of PTK2 mRNA CTD PMID:16300373 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rdh11 retinol dehydrogenase 11 affects expression ISO Phosgene affects the expression of RDH11 mRNA CTD PMID:16300373 NCBI chr 6:102,356,498...102,372,618
Ensembl chr 6:102,356,492...102,372,611
JBrowse link
G Rgs16 regulator of G-protein signaling 16 affects expression ISO Phosgene affects the expression of RGS16 mRNA CTD PMID:16300373 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rin1 Ras and Rab interactor 1 affects expression ISO Phosgene affects the expression of RIN1 mRNA CTD PMID:16300373 NCBI chr 1:220,335,036...220,342,319
Ensembl chr 1:220,335,254...220,342,297
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 affects expression ISO Phosgene affects the expression of RPS6KA2 mRNA CTD PMID:16300373 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G S100a14 S100 calcium binding protein A14 affects expression ISO Phosgene affects the expression of S100A14 mRNA CTD PMID:16300373 NCBI chr 2:189,913,433...189,919,947 JBrowse link
G Sars1 seryl-tRNA synthetase 1 affects expression ISO Phosgene affects the expression of SARS mRNA CTD PMID:16300373 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects expression ISO Phosgene affects the expression of SAT1 mRNA CTD PMID:16300373 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sema3b semaphorin 3B affects expression ISO Phosgene affects the expression of SEMA3B mRNA CTD PMID:16300373 NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N affects expression ISO Phosgene affects the expression of SERPINA3N mRNA CTD PMID:16300373 NCBI chr 6:128,073,344...128,080,878
Ensembl chr 6:127,941,526...128,080,889
JBrowse link
G Serpine1 serpin family E member 1 affects expression ISO Phosgene affects the expression of SERPINE1 mRNA CTD PMID:16300373 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpine2 serpin family E member 2 affects expression ISO Phosgene affects the expression of SERPINE2 mRNA CTD PMID:16300373 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sftpb surfactant protein B multiple interactions ISO [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with Phosgene] results in increased expression of SFTPB mRNA CTD PMID:25870319 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression ISO Phosgene affects the expression of SHANK3 mRNA CTD PMID:16300373 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 affects expression ISO Phosgene affects the expression of SIPA1 mRNA CTD PMID:16300373 NCBI chr 1:221,006,305...221,018,820
Ensembl chr 1:221,006,340...221,015,929
JBrowse link
G Slc3a2 solute carrier family 3 member 2 affects expression ISO Phosgene affects the expression of SLC3A2 mRNA CTD PMID:16300373 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc7a10 solute carrier family 7 member 10 affects expression ISO Phosgene affects the expression of SLC7A10 mRNA CTD PMID:16300373 NCBI chr 1:91,432,952...91,448,566
Ensembl chr 1:91,433,030...91,448,564
JBrowse link
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 affects expression ISO Phosgene affects the expression of SMARCE1 mRNA CTD PMID:16300373 NCBI chr10:87,116,827...87,138,890
Ensembl chr10:87,116,827...87,137,965
JBrowse link
G Sod2 superoxide dismutase 2 affects expression ISO Phosgene affects the expression of SOD2 mRNA CTD PMID:16300373 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 affects expression ISO Phosgene affects the expression of SOD3 mRNA CTD PMID:16300373 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sort1 sortilin 1 affects expression ISO Phosgene affects the expression of SORT1 mRNA CTD PMID:16300373 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sox18 SRY-box transcription factor 18 affects expression ISO Phosgene affects the expression of SOX18 mRNA CTD PMID:16300373 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
G Sox4 SRY-box transcription factor 4 affects expression ISO Phosgene affects the expression of SOX4 mRNA CTD PMID:16300373 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Sphk1 sphingosine kinase 1 affects expression ISO Phosgene affects the expression of SPHK1 mRNA CTD PMID:16300373 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 affects expression ISO Phosgene affects the expression of SPOCK2 mRNA CTD PMID:16300373 NCBI chr20:29,654,926...29,679,927
Ensembl chr20:29,655,226...29,677,926
JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 affects expression ISO Phosgene affects the expression of ST3GAL2 mRNA CTD PMID:16300373 NCBI chr19:43,273,251...43,324,265
Ensembl chr19:43,274,493...43,290,363
JBrowse link
G Stab1 stabilin 1 affects expression ISO Phosgene affects the expression of STAB1 mRNA CTD PMID:16300373 NCBI chr16:7,220,434...7,250,934
Ensembl chr16:7,222,067...7,250,924
JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 affects expression ISO Phosgene affects the expression of STARD13 mRNA CTD PMID:16300373 NCBI chr12:1,023,494...1,418,919
Ensembl chr12:1,023,531...1,195,591
JBrowse link
G Tbx2 T-box transcription factor 2 affects expression ISO Phosgene affects the expression of TBX2 mRNA CTD PMID:16300373 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link
G Tek TEK receptor tyrosine kinase affects expression ISO Phosgene affects the expression of TEK mRNA CTD PMID:16300373 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Thbs1 thrombospondin 1 affects expression ISO Phosgene affects the expression of THBS1 mRNA CTD PMID:16300373 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 affects expression ISO Phosgene affects the expression of TIE1 mRNA CTD PMID:16300373 NCBI chr 5:137,294,544...137,321,116
Ensembl chr 5:137,294,544...137,321,121
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Phosgene affects the expression of TIMP1 mRNA CTD PMID:16300373 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
ISO N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Phosgene results in decreased expression of TJP1 mRNA] CTD PMID:25870319 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A affects expression ISO Phosgene affects the expression of TNFRSF12A mRNA CTD PMID:16300373 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tpra1 transmembrane protein adipocyte associated 1 affects expression ISO Phosgene affects the expression of TPRA1 mRNA CTD PMID:16300373 NCBI chr 4:120,843,374...120,854,534
Ensembl chr 4:120,843,453...120,854,529
JBrowse link
G Tspo translocator protein affects expression ISO Phosgene affects the expression of TSPO mRNA CTD PMID:16300373 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Tuba1c tubulin, alpha 1C affects expression ISO Phosgene affects the expression of TUBA1C mRNA CTD PMID:16300373 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression ISO Phosgene affects the expression of TXNL1 mRNA CTD PMID:16300373 NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
JBrowse link
G Txnrd1 thioredoxin reductase 1 affects expression ISO Phosgene affects the expression of TXNRD1 mRNA CTD PMID:16300373 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
ISO
EXP
Phosgene results in decreased expression of VEGFA mRNA; Phosgene results in decreased expression of VEGFA protein
Phosgene results in increased expression of VEGFA mRNA alternative form
CTD PMID:15256155, PMID:18645720 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 affects expression ISO Phosgene affects the expression of WRNIP1 mRNA CTD PMID:16300373 NCBI chr17:32,933,395...32,953,641
Ensembl chr17:32,933,396...32,953,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      group 19698
        polyatomic entity 19697
          heteroatomic molecular entity 19622
            halide 17976
              acyl halide 191
                acyl chloride 180
                  2-chlorobenzoyl chloride 0
                  4-chlorobenzoyl chloride 0
                  5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate 0
                  acetyl chloride 0
                  benzoyl chloride 1
                  dichloroacetyl chloride 7
                  pentafluorobenzoyl chloride 0
                  phosgene 174
                  trifluoroacetyl chloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            heteroorganic entity 19148
                              organohalogen compound 17712
                                organochlorine compound 17466
                                  acyl chloride 180
                                    2-chlorobenzoyl chloride 0
                                    4-chlorobenzoyl chloride 0
                                    5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate 0
                                    acetyl chloride 0
                                    benzoyl chloride 1
                                    dichloroacetyl chloride 7
                                    pentafluorobenzoyl chloride 0
                                    phosgene 174
                                    trifluoroacetyl chloride 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.