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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:stilben-4-ol
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Accession:CHEBI:36664 term browser browse the term
Definition:A phenol having the structure of stilbene with a hydroxy function at C-4 of one of the phenyl rings; the stereochemistry across the alkene bond is not specified.
Synonyms:exact_synonym: 4-(2-phenylethenyl)phenol
 related_synonym: 4-(2-phenylvinyl)phenol;   4-hydroxystilbene;   Formula=C14H12O;   InChI=1S/C14H12O/c15-14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-11,15H;   InChIKey=QVLMUEOXQBUPAH-UHFFFAOYSA-N;   SMILES=[H]C(=C([H])c1ccc(O)cc1)c1ccccc1
 xref: Beilstein:2208345;   CAS:3839-46-1;   Gmelin:1405160
 xref_mesh: MESH:C064297



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stilben-4-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO 4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO 4-hydroxystilbene results in increased expression of ADIPOQ mRNA CTD PMID:23748787 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ar androgen receptor affects binding EXP 4-hydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4-hydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ctsd cathepsin D increases expression ISO 4-hydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 4-hydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4-hydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4-hydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Pgr progesterone receptor increases expression ISO 4-hydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO 4-hydroxystilbene results in decreased expression of PPARG mRNA CTD PMID:23748787 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Retn resistin decreases expression ISO 4-hydroxystilbene results in decreased expression of RETN mRNA CTD PMID:23748787 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO 4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein] CTD PMID:22865646 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Umod uromodulin multiple interactions ISO 4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of UMOD protein] CTD PMID:22865646 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    chemical entity 20058
      atom 20056
        nonmetal atom 19944
          carbon atom 19873
            organic molecular entity 19873
              olefinic compound 16500
                stilbene 3369
                  stilben-4-ol 12
                    cis-stilben-4-ol 0
                    trans-stilben-4-ol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic molecule 19819
                              organic cyclic compound 19581
                                carbocyclic compound 18521
                                  benzenoid aromatic compound 17773
                                    benzenes 17574
                                      stilbene 3369
                                        stilben-4-ol 12
                                          cis-stilben-4-ol 0
                                          trans-stilben-4-ol 0
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