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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:zinc group coordination entity
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Accession:CHEBI:36563 term browser browse the term
Synonyms:related_synonym: zinc group coordination compounds;   zinc group coordination entities


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cadmium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACADM mRNA CTD PMID:34416349 NCBI chr 6:137,541,481...137,575,544
Ensembl chr 6:137,541,381...137,595,108 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACOX1 mRNA CTD PMID:34416349 NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AKT1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of AKT1 protein CTD PMID:33493553
G ALOX15 arachidonate 15-lipoxygenase increases expression EXP Cadmium Chloride results in increased expression of ALOX15 mRNA CTD PMID:33626375 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,287,160...52,295,871 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase increases expression EXP Cadmium Chloride results in increased expression of ALOX5 mRNA CTD PMID:33626375 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,019...90,907,090 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) increases expression EXP Cadmium Chloride results in increased expression of AQP1 mRNA CTD PMID:20576581 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G ARG1 arginase 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ARG1 mRNA CTD PMID:34416349 NCBI chr 1:32,006,035...32,028,983
Ensembl chr 1:32,006,046...32,028,988 		JBrowse link
G ATF4 activating transcription factor 4 multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 protein; Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of ATF4 protein]
Cadmium Chloride results in increased expression of ATF4; Cadmium Chloride results in increased expression of ATF4 mRNA; Cadmium Chloride results in increased expression of ATF4 protein		 CTD PMID:16759985 PMID:20600546 PMID:33891997 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G ATF6 activating transcription factor 6 increases cleavage
multiple interactions		 EXP Cadmium Chloride results in increased cleavage of ATF6 protein
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased cleavage of ATF6 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF6 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF6 protein		 CTD PMID:17464326 PMID:33891997 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 multiple interactions
increases expression		 EXP [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAK1 mRNA; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAK1 protein] CTD PMID:26607349 PMID:33493553 NCBI chr 7:29,808,849...29,815,345
Ensembl chr 7:29,808,849...29,815,318 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of BAX protein
[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX protein; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]		 CTD PMID:26607349 PMID:33493553 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147 		JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BBC3 mRNA CTD PMID:33891997 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,045,685 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions
decreases expression		 EXP Cadmium Chloride results in increased expression of BCL2 protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 protein; Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]		 CTD PMID:23575899 PMID:26607349 PMID:33493553 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BCL2L11 BCL2 like 11 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BCL2L11 mRNA CTD PMID:33891997 NCBI chr 3:45,156,791...45,202,996
Ensembl chr 3:45,160,155...45,201,186 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 protein CTD PMID:33592257 PMID:34416349 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity		 EXP [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of and results in increased cleavage of CASP3 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP3 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; oxalomalic acid promotes the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]; Selenium inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein] CTD PMID:16785314 PMID:17383151 PMID:26607349 PMID:33493553 PMID:33891997 More... NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CASP9 caspase 9 increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of CASP9 protein
[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP9 mRNA; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]		 CTD PMID:26607349 PMID:33493553 PMID:33891997 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007 		JBrowse link
G CAT catalase decreases activity
multiple interactions
decreases expression		 EXP Cadmium Chloride results in decreased activity of CAT protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CAT mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CAT mRNA; CAT inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA]
Cadmium Chloride results in decreased expression of CAT mRNA		 CTD PMID:18086661 PMID:23904328 PMID:33493553 PMID:33626375 PMID:34416349 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCL2 mRNA CTD PMID:34416349 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CCL24 mRNA CTD PMID:34416349 NCBI chr 3:10,347,397...10,361,500 JBrowse link
G CLIC5 chloride intracellular channel 5 decreases expression
increases degradation
multiple interactions		 EXP Cadmium Chloride results in decreased expression of CLIC5 mRNA; Cadmium Chloride results in decreased expression of CLIC5 protein
Cadmium Chloride results in increased degradation of CLIC5 protein
bafilomycin A inhibits the reaction [Cadmium Chloride results in decreased expression of CLIC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride results in decreased expression of CLIC5 protein]; Cycloheximide promotes the reaction [Cadmium Chloride results in decreased expression of CLIC5 protein]		 CTD PMID:20576581 NCBI chr 7:40,683,044...40,808,017
Ensembl chr 7:40,682,907...40,863,886 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of COL3A1 mRNA CTD PMID:34416349 NCBI chr15:93,556,914...93,595,678
Ensembl chr15:93,526,603...93,596,363 		JBrowse link
G COL4A1 collagen type IV alpha 1 chain multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COL4A1 mRNA CTD PMID:34416349 NCBI chr11:76,858,332...76,997,409
Ensembl chr11:76,858,356...76,997,322 		JBrowse link
G CORT cortistatin multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CORT protein CTD PMID:34416349 NCBI chr 6:70,716,630...70,717,980
Ensembl chr 6:70,716,386...70,718,032 		JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COX4 mRNA CTD PMID:34416349 NCBI chr 6:3,131,017...3,137,619
Ensembl chr 6:3,131,019...3,137,530 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CPT1A mRNA CTD PMID:34416349 NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,911 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of CXCL8 mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CXCL8 mRNA		 CTD PMID:33626375 PMID:33891997 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CXCL9 mRNA CTD PMID:34416349 NCBI chr 8:71,665,541...71,670,236
Ensembl chr 8:71,663,501...71,670,271 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CYCS mRNA CTD PMID:33493553 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of DDIT3 mRNA
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 protein; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]		 CTD PMID:17464326 PMID:18086661 PMID:33891997 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G DENR density regulated re-initiation and release factor multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DENR mRNA CTD PMID:33592257 NCBI chr14:30,070,810...30,084,997
Ensembl chr14:30,069,487...30,084,949 		JBrowse link
G EGR1 early growth response 1 increases expression EXP Cadmium Chloride results in increased expression of EGR1 mRNA CTD PMID:7564105 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation
multiple interactions		 EXP Cadmium Chloride results in increased phosphorylation of EIF2A protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2A mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2A protein		 CTD PMID:16759985 PMID:17464326 PMID:33891997 NCBI chr13:90,761,453...90,804,274
Ensembl chr13:90,761,465...90,804,274 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
multiple interactions		 EXP Cadmium Chloride results in increased phosphorylation of EIF2AK3 protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2AK3 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2AK3 protein		 CTD PMID:17464326 PMID:33891997 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Cadmium Chloride results in increased phosphorylation of EIF2S1 protein CTD PMID:20600546 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ERN1 protein CTD PMID:33891997 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284 		JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ERO1A mRNA CTD PMID:33891997 NCBI chr 1:182,268,651...182,318,147
Ensembl chr 1:182,265,261...182,318,195 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DNM1L mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DNM1L protein CTD PMID:33493553 NCBI chr 5:41,571,054...41,636,058
Ensembl chr 5:41,570,282...41,636,028 		JBrowse link
G FIS1 fission, mitochondrial 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FIS1 mRNA CTD PMID:33592257 NCBI chr 3:8,938,250...8,942,102
Ensembl chr 3:8,937,453...8,946,955 		JBrowse link
G FN1 fibronectin 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FN1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FN1 protein CTD PMID:34416349 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,043 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of FOS mRNA
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]		 CTD PMID:7564105 PMID:18086661 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GCLC mRNA CTD PMID:33493553 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GCLM mRNA CTD PMID:33493553 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131 		JBrowse link
G GLRX glutaredoxin decreases activity
multiple interactions		 EXP Cadmium Chloride results in decreased activity of GLRX protein
GLRX protein inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; IDH2 protein inhibits the reaction [Cadmium Chloride results in decreased activity of GLRX protein]; oxalomalic acid promotes the reaction [Cadmium Chloride results in decreased activity of GLRX protein]		 CTD PMID:16785314 NCBI chr 2:102,425,580...102,437,851
Ensembl chr 2:102,425,580...102,437,858 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
decreases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPX1 mRNA
Cadmium Chloride results in decreased expression of GPX1 mRNA		 CTD PMID:33493553 PMID:33626375 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPX4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GPX4 mRNA CTD PMID:33493553 PMID:34416349 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 decreases expression
multiple interactions		 EXP Cadmium Chloride results in decreased expression of GSTO1 mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GSTO1 mRNA		 CTD PMID:33626375 PMID:34416349 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HIF1A mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HIF1A protein CTD PMID:33493553 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G HK2 hexokinase 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 mRNA CTD PMID:34416349 NCBI chr 3:68,155,656...68,231,187
Ensembl chr 3:68,153,835...68,231,615 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HMOX1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HMOX1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HMOX1 protein CTD PMID:33493553 PMID:33592257 PMID:34416349
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSP90B1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSP90B1 protein; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HSP90B1 mRNA] CTD PMID:17464326 PMID:18086661 PMID:33891997 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases phosphorylation
increases expression
multiple interactions
decreases expression
decreases response to substance		 EXP Cadmium Chloride results in increased phosphorylation of HSPA5 protein
Cadmium Chloride results in increased expression of HSPA5 mRNA; Cadmium Chloride results in increased expression of HSPA5 protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSPA5 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSPA5 protein; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA]; CAT inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA]; Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 protein]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 protein]; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA]; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 protein]
Cadmium Chloride results in decreased expression of HSPA5 mRNA
HSPA5 results in decreased susceptibility to Cadmium Chloride		 CTD PMID:16759985 PMID:17464326 PMID:18086661 PMID:20576581 PMID:20600546 More... NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G HYOU1 hypoxia up-regulated 1 decreases response to substance EXP HYOU1 results in decreased susceptibility to Cadmium Chloride CTD PMID:17464326 NCBI chr 9:46,264,929...46,277,056
Ensembl chr 9:46,264,933...46,276,995 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 affects binding
decreases response to substance
affects folding
multiple interactions
decreases activity		 EXP Cadmium Chloride binds to IDH2 protein
IDH2 protein results in decreased susceptibility to Cadmium Chloride
Cadmium Chloride affects the folding of IDH2 protein
[oxalomalic acid results in decreased activity of IDH2 protein] which results in increased susceptibility to Cadmium Chloride; Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; IDH2 protein inhibits the reaction [Cadmium Chloride results in decreased activity of GLRX protein]		 CTD PMID:16785314 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554 		JBrowse link
G IFNG interferon gamma multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IFNG mRNA CTD PMID:33592257 PMID:33891997 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IKBKB mRNA CTD PMID:33592257 NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,549 		JBrowse link
G IL10 interleukin 10 multiple interactions
decreases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL10 mRNA
Cadmium Chloride results in decreased expression of IL10 mRNA		 CTD PMID:33592257 PMID:33626375 PMID:34416349 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL13 interleukin 13 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL13 mRNA CTD PMID:33891997 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093 		JBrowse link
G IL17A interleukin 17A multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL17A mRNA CTD PMID:33592257 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL18 interleukin 18 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:33592257 PMID:34416349 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1A mRNA CTD PMID:33592257 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121 		JBrowse link
G IL2 interleukin 2 multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL2 mRNA
Cadmium Chloride results in increased expression of IL2 mRNA		 CTD PMID:33592257 PMID:33626375 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4 interleukin 4 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IL4 mRNA CTD PMID:33891997 PMID:34416349 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL6 mRNA
Cadmium Chloride results in increased expression of IL6 mRNA		 CTD PMID:33592257 PMID:33626375 PMID:33891997 PMID:34416349 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G IL7 interleukin 7 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL7 mRNA CTD PMID:33592257 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ITPR1 mRNA CTD PMID:33891997 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of JUN mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JUN protein		 CTD PMID:7564105 PMID:33891997 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA mRNA CTD PMID:34416349 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715 		JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B protein
Cadmium Chloride results in increased expression of IL1B mRNA		 CTD PMID:33592257 PMID:33626375 PMID:34416349
G LRP2 LDL receptor related protein 2 decreases expression
increases degradation
multiple interactions		 EXP Cadmium Chloride results in decreased expression of LRP2 mRNA; Cadmium Chloride results in decreased expression of LRP2 protein
Cadmium Chloride results in increased degradation of LRP2 protein
bafilomycin A inhibits the reaction [Cadmium Chloride results in decreased expression of LRP2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride results in decreased expression of LRP2 protein]; Cycloheximide promotes the reaction [Cadmium Chloride results in decreased expression of LRP2 protein]		 CTD PMID:20576581 NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; Selenium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; XBP1 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:10696784 PMID:17383151 PMID:17464326 PMID:18086661 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Selenium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:10696784 PMID:17383151 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
G MFF mitochondrial fission factor multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFF mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFF protein CTD PMID:33493553 NCBI chr15:128,768,441...128,799,355
Ensembl chr15:128,768,348...128,799,344 		JBrowse link
G MFN1 mitofusin 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN1 protein CTD PMID:33493553 PMID:33592257 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481 		JBrowse link
G MFN2 mitofusin 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN2 protein CTD PMID:33493553 PMID:33592257 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438 		JBrowse link
G MIR125A microRNA mir-125a decreases expression
multiple interactions		 EXP Cadmium Chloride results in decreased expression of MIR125A mRNA
[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein; [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein; [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein; [Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein; Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAK1 protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of BAX protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; MIR125A mRNA inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAK1 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of BAX protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP3 protein]; Sodium Selenite inhibits the reaction [[Cadmium Chloride co-treated with MIR125A mRNA mutant form] results in increased expression of CASP9 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride promotes the reaction [MIR125A mRNA mutant form results in decreased expression of BCL2 protein]]		 CTD PMID:26607349 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645 		JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase increases expression EXP Cadmium Chloride results in increased expression of MLKL mRNA; Cadmium Chloride results in increased expression of MLKL protein CTD PMID:33626375 NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein CTD PMID:34416349 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein CTD PMID:34416349 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MRC1 mannose receptor C-type 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MRC1 mRNA CTD PMID:34416349 NCBI chr10:44,107,926...44,226,734
Ensembl chr10:44,107,072...44,226,733 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Cadmium Chloride results in increased expression of MYC mRNA CTD PMID:7564105 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NDUFB8 mRNA CTD PMID:34416349 NCBI chr14:111,626,827...111,633,548
Ensembl chr14:111,626,097...111,633,564 		JBrowse link
G NFE2 nuclear factor, erythroid 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NFE2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NFE2 protein CTD PMID:33592257 NCBI chr 5:19,494,672...19,501,810
Ensembl chr 5:19,494,677...19,501,810 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions		 EXP Cadmium Chloride results in decreased expression of NFE2L2 mRNA; Cadmium Chloride results in decreased expression of NFE2L2 protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NFE2L2 mRNA		 CTD PMID:33626375 PMID:34416349 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NFKB1 mRNA CTD PMID:33592257 PMID:34416349 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NFKBIA mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of and results in increased ubiquitination of NFKBIA protein CTD PMID:33592257 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G NKRF NFKB repressing factor increases expression EXP Cadmium Chloride results in increased expression of NKRF mRNA CTD PMID:33626375 NCBI chr  X:98,008,870...98,025,423
Ensembl chr  X:98,007,910...98,025,373 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein CTD PMID:33592257 PMID:34416349 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of NOS2 mRNA; Cadmium Chloride results in increased expression of NOS2 protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOS2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOS2 protein		 CTD PMID:33592257 PMID:33626375 PMID:34416349 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions		 EXP Cadmium Chloride results in decreased expression of NQO1 mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NQO1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NQO1 mRNA		 CTD PMID:33493553 PMID:33626375 PMID:34416349 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590 		JBrowse link
G NRF1 nuclear respiratory factor 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NRF1 mRNA CTD PMID:33592257 NCBI chr18:19,008,408...19,142,678
Ensembl chr18:18,998,930...19,142,628 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of OPA1 mRNA CTD PMID:33592257 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,796...130,719,083 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 EXP GLRX protein inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; oxalomalic acid promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:16785314 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PDK1 mRNA CTD PMID:34416349 NCBI chr15:78,608,394...78,650,958
Ensembl chr15:78,608,432...78,652,962 		JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PFKFB3 mRNA CTD PMID:34416349 NCBI chr10:64,776,315...64,859,118
Ensembl chr10:64,776,315...64,802,287 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PIK3CG mRNA CTD PMID:33493553 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PMAIP1 mRNA CTD PMID:33891997 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164 		JBrowse link
G POMC proopiomelanocortin multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of POMC protein CTD PMID:34416349 NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PPARA mRNA CTD PMID:34416349 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein CTD PMID:33592257 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PRKAA1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAA1 mRNA CTD PMID:33592257 PMID:34416349 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAA2 mRNA CTD PMID:34416349 NCBI chr 6:155,683,392...155,754,283
Ensembl chr 6:155,681,784...155,754,278 		JBrowse link
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAB1 mRNA CTD PMID:34416349 NCBI chr14:33,201,359...33,217,641
Ensembl chr14:33,201,669...33,217,539 		JBrowse link
G PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAG1 mRNA CTD PMID:34416349 NCBI chr 5:15,033,051...15,049,676
Ensembl chr 5:15,033,058...15,049,735 		JBrowse link
G PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKAG3 mRNA CTD PMID:34416349 NCBI chr15:120,859,486...120,866,308
Ensembl chr15:120,855,201...120,866,332 		JBrowse link
G PTGER3 prostaglandin E receptor 3 increases expression EXP Cadmium Chloride results in increased expression of PTGER3 mRNA CTD PMID:33626375 NCBI chr 6:141,958,955...142,160,437
Ensembl chr 6:141,958,955...142,161,286 		JBrowse link
G PTGES3 prostaglandin E synthase 3 increases expression EXP Cadmium Chloride results in increased expression of PTGES3 protein CTD PMID:33626375 NCBI chr 5:22,000,335...22,022,830
Ensembl chr 5:22,000,341...22,021,660 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of PTGS2 mRNA; Cadmium Chloride results in increased expression of PTGS2 protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PTGS2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PTGS2 protein		 CTD PMID:33592257 PMID:33626375 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit affects localization
multiple interactions		 EXP Cadmium Chloride affects the localization of RELA protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein		 CTD PMID:23575899 PMID:34416349 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression EXP Cadmium Chloride results in increased expression of RIPK1 mRNA; Cadmium Chloride results in increased expression of RIPK1 protein CTD PMID:33626375 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 increases expression EXP Cadmium Chloride results in increased expression of RIPK3 mRNA; Cadmium Chloride results in increased expression of RIPK3 protein CTD PMID:33626375 NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SDHB mRNA CTD PMID:34416349 NCBI chr 6:75,648,362...75,678,111
Ensembl chr 6:75,648,215...75,678,378 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 protein CTD PMID:34416349 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SMAD2 SMAD family member 2 increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of SMAD2 mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SMAD2 mRNA		 CTD PMID:33626375 PMID:34416349 NCBI chr 1:97,415,360...97,511,388
Ensembl chr 1:97,415,716...97,511,357 		JBrowse link
G SMAD3 SMAD family member 3 increases expression EXP Cadmium Chloride results in increased expression of SMAD3 mRNA CTD PMID:33626375 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G SMAD4 SMAD family member 4 increases expression EXP Cadmium Chloride results in increased expression of SMAD4 mRNA CTD PMID:33626375 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029 		JBrowse link
G SMAD7 SMAD family member 7 decreases expression EXP Cadmium Chloride results in decreased expression of SMAD7 mRNA; Cadmium Chloride results in decreased expression of SMAD7 protein CTD PMID:33626375 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,514,267...98,542,382 		JBrowse link
G SOD1 superoxide dismutase 1 decreases expression
multiple interactions		 EXP Cadmium Chloride results in decreased expression of SOD1 mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SOD1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SOD1 mRNA		 CTD PMID:33493553 PMID:33626375 PMID:34416349 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G SOD2 superoxide dismutase 2 decreases response to substance
multiple interactions
decreases expression		 EXP SOD2 results in decreased susceptibility to Cadmium Chloride
[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SOD2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SOD2 mRNA; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA]; SOD2 inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 protein]; SOD2 inhibits the reaction [Cadmium Chloride results in increased splicing of XBP1 mRNA]
Cadmium Chloride results in decreased expression of SOD2 mRNA		 CTD PMID:18086661 PMID:33493553 PMID:33626375 PMID:34416349 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
G TFAM transcription factor A, mitochondrial multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TFAM mRNA CTD PMID:33592257 NCBI chr14:92,261,713...92,279,731
Ensembl chr14:92,259,403...92,279,731 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TGFB1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TGFB1 protein; Cadmium Chloride results in increased expression of and results in increased cleavage of TGFB1 protein
Cadmium Chloride results in increased expression of TGFB1 mRNA; Cadmium Chloride results in increased expression of TGFB1 protein		 CTD PMID:33626375 PMID:34416349 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 increases expression EXP Cadmium Chloride results in increased expression of TGFBR1 mRNA CTD PMID:33626375 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 increases expression EXP Cadmium Chloride results in increased expression of TGFBR2 mRNA CTD PMID:33626375 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TIMP1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TIMP1 protein CTD PMID:34416349 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,296 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 protein CTD PMID:34416349 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834 		JBrowse link
G TLR4 toll like receptor 4 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TLR4 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TLR4 protein CTD PMID:34416349 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions		 EXP Cadmium Chloride results in increased expression of TNF mRNA; Cadmium Chloride results in increased expression of TNF protein
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TNF mRNA		 CTD PMID:33626375 PMID:33891997 PMID:34416349 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions
increases expression		 EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TNFRSF1A mRNA
Cadmium Chloride results in increased expression of TNFRSF1A mRNA; Cadmium Chloride results in increased expression of TNFRSF1A protein		 CTD PMID:33592257 PMID:33626375 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,051...64,331,909 		JBrowse link
G TRAF2 TNF receptor associated factor 2 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRAF2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRAF2 protein CTD PMID:33891997
G TRAF6 TNF receptor associated factor 6 multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRAF6 mRNA CTD PMID:33592257 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,804...24,626,072 		JBrowse link
G TWNK twinkle mtDNA helicase multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TWNK mRNA CTD PMID:33592257 NCBI chr14:112,068,463...112,076,169
Ensembl chr14:112,069,925...112,075,792 		JBrowse link
G UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII multiple interactions EXP [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UQCRQ mRNA CTD PMID:34416349 NCBI chr 2:135,186,366...135,188,237
Ensembl chr 2:135,186,501...135,188,293 		JBrowse link
G XBP1 X-box binding protein 1 increases splicing
multiple interactions		 EXP Cadmium Chloride results in increased splicing of XBP1 mRNA
[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of XBP1 mRNA alternative form; SOD2 inhibits the reaction [Cadmium Chloride results in increased splicing of XBP1 mRNA]; XBP1 affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]		 CTD PMID:17464326 PMID:18086661 PMID:33891997 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
mercury dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) multiple interactions EXP Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water] CTD PMID:16534851 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G ATF4 activating transcription factor 4 increases expression EXP Mercuric Chloride results in increased expression of ATF4 protein CTD PMID:16759985 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation EXP Mercuric Chloride results in increased phosphorylation of EIF2A protein CTD PMID:16759985 NCBI chr13:90,761,453...90,804,274
Ensembl chr13:90,761,465...90,804,274 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of FOS mRNA]
Mercuric Chloride results in increased expression of FOS mRNA; Mercuric Chloride results in increased expression of FOS protein		 CTD PMID:9463523 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression EXP Mercuric Chloride results in increased expression of HSP90B1 mRNA CTD PMID:17464326 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Mercuric Chloride results in increased expression of HSPA5 mRNA CTD PMID:17464326 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
increases phosphorylation		 EXP Mercuric Chloride results in increased expression of JUN mRNA; Mercuric Chloride results in increased expression of JUN protein
Mercuric Chloride results in increased phosphorylation of JUN protein		 CTD PMID:10696784 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation EXP Mercuric Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10696784 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases phosphorylation EXP Mercuric Chloride results in increased phosphorylation of MAPK9 protein CTD PMID:10696784 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
zinc protoporphyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions EXP zinc protoporphyrin inhibits the reaction [1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased degradation of GUCY1B1 protein] CTD PMID:19466990 NCBI chr 8:44,544,364...44,604,690
Ensembl chr 8:44,544,179...44,604,687 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5164
    chemical entity 5164
      molecular entity 5163
        polyatomic entity 5143
          heteroatomic molecular entity 5113
            coordination entity 158
              zinc group coordination entity 134
                cadmium coordination entity + 133
                mercury coordination entity + 9
                zinc coordination entity + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 5164
    subatomic particle 5155
      composite particle 5155
        hadron 5155
          baryon 5155
            nucleon 5155
              atomic nucleus 5155
                atom 5155
                  metal atom 245
                    transition element atom 200
                      d-block element atom 200
                        zinc group element atom 170
                          zinc group molecular entity 165
                            zinc group coordination entity 134
                              cadmium coordination entity + 133
                              mercury coordination entity + 9
                              zinc coordination entity + 1
paths to the root