Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:chlorzoxazone
go back to main search page
Accession:CHEBI:3655 term browser browse the term
Definition:A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Synonyms:exact_synonym: 5-chloro-1,3-benzoxazol-2-ol
 related_synonym: 2-hydroxy-5-chlorobenzoxazole;   5-chloro-2(3H)-benzoxazolone;   5-chloro-2-benzoxazolinone;   5-chloro-2-benzoxazolol;   5-chloro-2-benzoxazolone;   5-chloro-2-hydroxybenzoxazole;   5-chlorobenzoxazolidone;   5-chlorobenzoxazolin-2-one;   Formula=C7H4ClNO2;   InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10);   InChIKey=TZFWDZFKRBELIQ-UHFFFAOYSA-N;   SMILES=Oc1nc2cc(Cl)ccc2o1;   chlorzoxane;   chlorzoxazona;   chlorzoxazonum
 alt_id: CHEBI:47330
 xref: Beilstein:638882 "Beilstein";   CAS:95-25-0 "ChemIDplus";   CAS:95-25-0 "KEGG COMPOUND";   CAS:95-25-0 "NIST Chemistry WebBook";   DrugBank:DB00356;   Drug_Central:626 "DrugCentral";   HMDB:HMDB0014500;   KEGG:C07931;   KEGG:D00771;   LINCS:LSM-6011
 xref_mesh: MESH:D002753
 xref: PDBeChem:CLW;   PMID:10640318 "Europe PMC";   PMID:11727787 "Europe PMC";   PMID:12437348 "Europe PMC";   PMID:16763012 "Europe PMC";   PMID:16859676 "Europe PMC";   PMID:17621748 "Europe PMC";   PMID:21195386 "Europe PMC";   PMID:23975871 "Europe PMC";   PMID:24210069 "Europe PMC";   PMID:25815637 "Europe PMC";   PMID:6631711 "Europe PMC";   Patent:US2895877;   Reaxys:638882 "Reaxys";   Wikipedia:Chlorzoxazone


show annotations for term's descendants       view all columns           Sort by:
 
chlorzoxazone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyb5a cytochrome b5 type A JBrowse link 18 81,694,818 81,726,821 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:6480464
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 JBrowse link 1 258,796,624 258,877,023 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Kcnn4 potassium calcium-activated channel subfamily N member 4 JBrowse link 1 81,227,855 81,245,986 RGD:6480464
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      application 19232
        pharmaceutical 19094
          drug 19094
            neuromuscular agent 1284
              muscle relaxant 1279
                chlorzoxazone 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic molecule 19337
                              organic cyclic compound 19089
                                organic heterocyclic compound 18164
                                  organic heteropolycyclic compound 17427
                                    organic heterobicyclic compound 15905
                                      benzoxazole 112
                                        1,3-benzoxazoles 41
                                          chlorzoxazone 15
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.