kaurane - Ontology Report - Rat Genome Database

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	kaurane	go back to main search page
Accession:	CHEBI:36539	browse the term
Definition:	A diterpene that has formula C20H34.
Synonyms:	related_synonym:	Formula=C20H34; InChI=1S/C20H34/c1-14-12-20-11-8-16-18(2,3)9-5-10-19(16,4)17(20)7-6-15(14)13-20/h14-17H,5-13H2,1-4H3/t14-,15+,16+,17-,19+,20+/m1/s1; InChIKey=IVZWRQBQDVHDNG-XWIHJEQYSA-N; SMILES=[H][C@@]12CC[C@@]34C[C@@H](C)[C@@H](CC[C@]3([H])[C@@]1(C)CCCC2(C)C)C4
	xref:	Beilstein:6791834
	cyclic_relationship:	is_enantiomer_of CHEBI:36540

show annotations for term's descendants Sort by:

Rat (11) Mouse (11) Human (11) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (11)

Longikaurin A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

increases expression

longikaurin A results in increased expression of BAX protein

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression

longikaurin A results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920

G

caspase 3

increases expression

longikaurin A results in increased expression of CASP3 protein modified form

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases expression

longikaurin A results in increased expression of CASP9 protein modified form

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

cyclin B1

decreases expression

longikaurin A results in decreased expression of CCNB1 protein

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin-dependent kinase 1

decreases expression

longikaurin A results in decreased expression of CDK1 protein

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cytochrome c, somatic

increases expression

longikaurin A results in increased expression of CYCS protein

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054

G

H2A.X variant histone

increases expression

longikaurin A results in increased expression of H2AX protein modified form

NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239

G

mitogen-activated protein kinase 8

increases phosphorylation
multiple interactions

longikaurin A results in increased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK9 protein]

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

poly (ADP-ribose) polymerase 1

increases expression

longikaurin A results in increased expression of PARP1 protein modified form

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	20056
chemical entity	20055
atom	20054
nonmetal atom	19945
carbon atom	19875
organic molecular entity	19875
organic fundamental parent	18653
natural product fundamental parent	14668
terpenoid fundamental parent	3743
kaurane	11
kaurane diterpenoid +	11
Path 2
Term	Annotations
CHEBI ontology	20056
subatomic particle	20054
composite particle	20054
hadron	20054
baryon	20054
nucleon	20054
atomic nucleus	20054
atom	20054
main group element atom	19956
main group molecular entity	19956
s-block molecular entity	19752
hydrogen molecular entity	19745
hydrides	19114
organic hydride	18653
organic fundamental parent	18653
hydrocarbon	18389
terpene	13624
diterpene	12711
kaurane	11
kaurane diterpenoid +	11

paths to the root