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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:kaurane
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Accession:CHEBI:36539 term browser browse the term
Definition:A diterpene that has formula C20H34.
Synonyms:related_synonym: Formula=C20H34;   InChI=1S/C20H34/c1-14-12-20-11-8-16-18(2,3)9-5-10-19(16,4)17(20)7-6-15(14)13-20/h14-17H,5-13H2,1-4H3/t14-,15+,16+,17-,19+,20+/m1/s1;   InChIKey=IVZWRQBQDVHDNG-XWIHJEQYSA-N;   SMILES=[H][C@@]12CC[C@@]34C[C@@H](C)[C@@H](CC[C@]3([H])[C@@]1(C)CCCC2(C)C)C4
 xref: Beilstein:6791834
 cyclic_relationship: is_enantiomer_of CHEBI:36540

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Longikaurin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO longikaurin A results in increased expression of BAX protein CTD PMID:28801140 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO longikaurin A results in decreased expression of BCL2 protein CTD PMID:28801140 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Casp3 caspase 3 increases expression ISO longikaurin A results in increased expression of CASP3 protein modified form CTD PMID:28801140 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 increases expression ISO longikaurin A results in increased expression of CASP9 protein modified form CTD PMID:28801140 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO longikaurin A results in decreased expression of CCNB1 protein CTD PMID:28801140 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO longikaurin A results in decreased expression of CDK1 protein CTD PMID:28801140 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO longikaurin A results in increased expression of CYCS protein CTD PMID:28801140 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO longikaurin A results in increased expression of H2AX protein modified form CTD PMID:28801140 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO longikaurin A results in increased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]		 CTD PMID:28801140 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK9 protein] CTD PMID:28801140 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO longikaurin A results in increased expression of PARP1 protein modified form CTD PMID:28801140 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      atom 19784
        nonmetal atom 19659
          carbon atom 19563
            organic molecular entity 19563
              organic fundamental parent 18249
                natural product fundamental parent 12797
                  terpenoid fundamental parent 1958
                    kaurane 11
                      kaurane diterpenoid + 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            organic hydride 18249
                              organic fundamental parent 18249
                                hydrocarbon 17969
                                  terpene 9594
                                    diterpene 8426
                                      kaurane 11
                                        kaurane diterpenoid + 11
paths to the root

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