kaurane - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	kaurane	go back to main search page
Accession:	CHEBI:36539	browse the term
Definition:	A diterpene that has formula C20H34.
Synonyms:	related_synonym:	Formula=C20H34; InChI=1S/C20H34/c1-14-12-20-11-8-16-18(2,3)9-5-10-19(16,4)17(20)7-6-15(14)13-20/h14-17H,5-13H2,1-4H3/t14-,15+,16+,17-,19+,20+/m1/s1; InChIKey=IVZWRQBQDVHDNG-XWIHJEQYSA-N; SMILES=[H][C@@]12CC[C@@]34C[C@@H](C)[C@@H](CC[C@]3([H])[C@@]1(C)CCCC2(C)C)C4
	xref:	Beilstein:6791834
	cyclic_relationship:	is_enantiomer_of CHEBI:36540

show annotations for term's descendants Sort by:

Rat (11) Mouse (11) Human (11) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) All
Genes (11)

Longikaurin A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

increases expression

longikaurin A results in increased expression of BAX protein

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression

longikaurin A results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920

G

caspase 3

increases expression

longikaurin A results in increased expression of CASP3 protein modified form

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases expression

longikaurin A results in increased expression of CASP9 protein modified form

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

cyclin B1

decreases expression

longikaurin A results in decreased expression of CCNB1 protein

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin-dependent kinase 1

decreases expression

longikaurin A results in decreased expression of CDK1 protein

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cytochrome c, somatic

increases expression

longikaurin A results in increased expression of CYCS protein

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054

G

H2A.X variant histone

increases expression

longikaurin A results in increased expression of H2AX protein modified form

NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239

G

mitogen-activated protein kinase 8

increases phosphorylation
multiple interactions

longikaurin A results in increased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK9 protein]

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

poly (ADP-ribose) polymerase 1

increases expression

longikaurin A results in increased expression of PARP1 protein modified form

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19808
chemical entity	19808
atom	19807
nonmetal atom	19694
carbon atom	19616
organic molecular entity	19616
organic fundamental parent	18350
natural product fundamental parent	13394
terpenoid fundamental parent	3512
kaurane	11
kaurane diterpenoid +	11
Path 2
Term	Annotations
CHEBI ontology	19808
subatomic particle	19807
composite particle	19807
hadron	19807
baryon	19807
nucleon	19807
atomic nucleus	19807
atom	19807
main group element atom	19704
main group molecular entity	19704
s-block molecular entity	19489
hydrogen molecular entity	19484
hydrides	18841
organic hydride	18350
organic fundamental parent	18350
hydrocarbon	18061
terpene	12718
diterpene	11516
kaurane	11
kaurane diterpenoid +	11

paths to the root