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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:eudesmane
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Accession:CHEBI:36522 term browser browse the term
Definition:A terpenoid fundamental parent that has formula C15H28.
Synonyms:related_synonym: (1R,4aR,7R,8aS)-1,4a-dimethyl-7-(propan-2-yl)decahydronaphthalene;   (1R,4aR,7R,8aS)-7-isopropyl-1,4a-dimethyldecahydronaphthalene;   Formula=C15H28;   InChI=1S/C15H28/c1-11(2)13-7-9-15(4)8-5-6-12(3)14(15)10-13/h11-14H,5-10H2,1-4H3/t12-,13-,14+,15-/m1/s1;   InChIKey=DYEQPYSFRWUNNV-APIJFGDWSA-N;   SMILES=[H][C@@]12C[C@@H](CC[C@@]1(C)CCC[C@H]2C)C(C)C
 xref: Beilstein:2498027;   CAS:473-11-0


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beta-eudesmol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased cleavage of CASP1 protein] CTD PMID:30148989 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of CXCL2 protein] CTD PMID:30148989 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of ICAM1 protein] CTD PMID:30148989 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of IL1B protein] CTD PMID:30148989 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of TNF protein] CTD PMID:30148989 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of TSLP protein] CTD PMID:30148989 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
isoalantolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression ISO isoalantolactone results in increased expression of CASP3 protein modified form CTD PMID:29800641 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
increases expression
ISO isoalantolactone results in increased cleavage of CASP7 protein
Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; TNFRSF10B protein promotes the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]
CTD PMID:29800641 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
multiple interactions
increases cleavage
ISO isoalantolactone results in increased expression of PARP1 protein modified form
Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; TNFRSF10B protein promotes the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]
isoalantolactone results in increased cleavage of PARP1 protein
CTD PMID:29800641 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          carbon atom 19630
            organic molecular entity 19630
              organic fundamental parent 18353
                natural product fundamental parent 13397
                  terpenoid fundamental parent 3515
                    eudesmane 9
                      eudesmane sesquiterpenoid + 9
                      selina-4(15),7(11)-diene 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            organic hydride 18353
                              organic fundamental parent 18353
                                hydrocarbon 18066
                                  terpene 12711
                                    sesquiterpene 2727
                                      eudesmane 9
                                        eudesmane sesquiterpenoid + 9
                                        selina-4(15),7(11)-diene 0
paths to the root