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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:eudesmane
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Accession:CHEBI:36522 term browser browse the term
Definition:A terpenoid fundamental parent that has formula C15H28.
Synonyms:related_synonym: (1R,4aR,7R,8aS)-1,4a-dimethyl-7-(propan-2-yl)decahydronaphthalene;   (1R,4aR,7R,8aS)-7-isopropyl-1,4a-dimethyldecahydronaphthalene;   Formula=C15H28;   InChI=1S/C15H28/c1-11(2)13-7-9-15(4)8-5-6-12(3)14(15)10-13/h11-14H,5-10H2,1-4H3/t12-,13-,14+,15-/m1/s1;   InChIKey=DYEQPYSFRWUNNV-APIJFGDWSA-N;   SMILES=[H][C@@]12C[C@@H](CC[C@@]1(C)CCC[C@H]2C)C(C)C
 xref: Beilstein:2498027;   CAS:473-11-0


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beta-eudesmol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased cleavage of CASP1 protein] CTD PMID:30148989 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of CXCL2 protein] CTD PMID:30148989 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of ICAM1 protein] CTD PMID:30148989 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of IL1B protein] CTD PMID:30148989 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of TNF protein] CTD PMID:30148989 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of TSLP protein] CTD PMID:30148989 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
isoalantolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression ISO isoalantolactone results in increased expression of CASP3 protein modified form CTD PMID:29800641 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
increases expression
ISO isoalantolactone results in increased cleavage of CASP7 protein
Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; TNFRSF10B protein promotes the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]
CTD PMID:29800641 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
multiple interactions
increases cleavage
ISO isoalantolactone results in increased expression of PARP1 protein modified form
Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; TNFRSF10B protein promotes the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]
isoalantolactone results in increased cleavage of PARP1 protein
CTD PMID:29800641 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              organic fundamental parent 18265
                natural product fundamental parent 12802
                  terpenoid fundamental parent 1966
                    eudesmane 9
                      eudesmane sesquiterpenoid + 9
                      selina-4(15),7(11)-diene 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    main group molecular entity 19696
                      s-block molecular entity 19456
                        hydrogen molecular entity 19447
                          hydrides 18703
                            organic hydride 18265
                              organic fundamental parent 18265
                                hydrocarbon 17986
                                  terpene 9609
                                    sesquiterpene 2694
                                      eudesmane 9
                                        eudesmane sesquiterpenoid + 9
                                        selina-4(15),7(11)-diene 0
paths to the root