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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:3651 term browser browse the term
Definition:A thioxanthene that has formula C18H18ClNS.
Synonyms:exact_synonym: 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
 related_synonym: Alpha-Chlorprothixene;   Chlorprothixen;   Chlorprothixine;   Chlorprotixen;   Chlorprotixene;   Chlorprotixine;   Chlothixen;   Formula=C18H18ClNS;   InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3;   InChIKey=WSPOMRSOLSGNFJ-UHFFFAOYSA-N;   SMILES=[H]C(CCN(C)C)=C1c2ccccc2Sc2ccc(Cl)cc12;   chlorprothixenum;   clorprotixeno
 xref: Beilstein:89898;   DrugBank:DB01239;   HMDB:HMDB0015369;   KEGG:C07953;   KEGG:D00790;   LINCS:LSM-3310
 xref_mesh: MESH:D002749
 xref: Patent:GB829763;   Patent:US3046283
 cyclic_relationship: is_conjugate_base_of CHEBI:180503

show annotations for term's descendants           Sort by:
(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19659
    role 19634
      biological role 19633
        pharmacological role 18933
          analgesic 14631
            non-narcotic analgesic 13788
              chlorprothixene 3
                (E)-chlorprothixene 0
                (Z)-chlorprothixene 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19659
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19700
                atom 19658
                  main group element atom 19607
                    main group molecular entity 19649
                      s-block molecular entity 19457
                        hydrogen molecular entity 19450
                          hydrides 18928
                            inorganic hydride 17765
                              pnictogen hydride 17748
                                nitrogen hydride 17633
                                  azane 17403
                                    ammonia 17402
                                      organic amino compound 17402
                                        tertiary amino compound 9087
                                          chlorprothixene 3
                                            (E)-chlorprothixene 0
                                            (Z)-chlorprothixene 3
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