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Accession:CHEBI:3650 term browser browse the term
Definition:An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
Synonyms:related_synonym: 1-(p-chlorobenzenesulfonyl)-3-propylurea;   1-(p-chlorophenylsulfonyl)-3-propylurea;   1-propyl-3-(p-chlorobenzenesulfonyl)urea;   4-chloro-N-((propylamino)carbonyl)benzenesulfonamide;   Formula=C10H13ClN2O3S;   InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14);   InChIKey=RKWGIWYCVPQPMF-UHFFFAOYSA-N;   N-(4-chlorophenylsulfonyl)-N'-propylurea;   N-(p-chlorobenzenesulfonyl)-N'-propylurea;   SMILES=CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1;   chlorpropamidum;   clorpropamida;   n-propyl-N'-(p-chlorobenzenesulfonyl)urea;   n-propyl-N'-p-chlorophenylsulfonylcarbamide
 alt_id: CHEBI:108516
 xref: Beilstein:2218363 "Beilstein";   CAS:94-20-2 "ChemIDplus";   CAS:94-20-2 "KEGG DRUG";   CAS:94-20-2 "NIST Chemistry WebBook";   DrugBank:DB00672;   Drug_Central:622 "DrugCentral";   HMDB:HMDB0014810;   KEGG:D00271;   LINCS:LSM-6695
 xref_mesh: MESH:D002747
 xref: PMID:10891117 "ChEMBL";   PMID:2657066 "ChEMBL";   PMID:3806586 "ChEMBL";   Patent:GB853555;   Patent:US3349124;   Reaxys:2218363 "Reaxys";   Wikipedia:Chlorpropamide

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chlorpropamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:6480464
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 JBrowse link 1 102,103,093 102,107,134 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        pharmaceutical 19108
          drug 19108
            hypoglycemic agent 3741
              chlorpropamide 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                monocarboxylic acid amide 13185
                                                  urea 4948
                                                    ureas 4946
                                                      N-sulfonylurea 93
                                                        chlorpropamide 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.