CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: drimane
Accession: CHEBI:36474
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Definition: A terpenoid fundamental parent that has formula C15H28.
Synonyms: related_synonym: (4aR,5S,6S,8aS)-1,1,4a,5,6-pentamethyldecahydronaphthalene; Formula=C15H28; InChI=1S/C15H28/c1-11-7-8-13-14(3,4)9-6-10-15(13,5)12(11)2/h11-13H,6-10H2,1-5H3/t11-,12-,13-,15+/m0/s1; InChIKey=CVRSZZJUWRLRDE-PWNZVWSESA-N; SMILES=[H][C@@]12CC[C@H](C)[C@H](C)[C@@]1(C)CCCC2(C)C
xref: Beilstein:2959385
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
drimenol results in increased expression of BAX protein
CTD
PMID:30935903
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
drimenol results in decreased expression of BCL2 protein
CTD
PMID:30935903
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Casp3
caspase 3
increases activity
ISO
drimenol results in increased activity of CASP3 protein
CTD
PMID:30935903
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Casp9
caspase 9
increases cleavage
ISO
drimenol results in increased cleavage of CASP9 protein
CTD
PMID:30935903
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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