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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chlorothiazide
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Accession:CHEBI:3640 term browser browse the term
Definition:4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.
Synonyms:exact_synonym: 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
 related_synonym: 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide;   6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide;   Formula=C7H6ClN3O4S2;   InChI=1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13);   InChIKey=JBMKAUGHUNFTOL-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc2c(NC=NS2(=O)=O)cc1Cl;   chlorothiazidum;   clorotiazida
 alt_id: CHEBI:162615
 xref: Beilstein:1084805;   CAS:58-94-6;   DrugBank:DB00880;   Drug_Central:609;   KEGG:C07461;   KEGG:D00519;   LINCS:LSM-5942;   PMID:10891117;   PMID:2160536;   PMID:28166217;   PMID:29438107;   PMID:3712385;   Patent:US2809194;   Wikipedia:Chlorothiazide



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        pharmaceutical 19503
          drug 19471
            diuretic 4106
              chlorothiazide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organonitrogen heterocyclic compound 18154
                                    thiazide 79
                                      benzothiadiazine 79
                                        chlorothiazide 0
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