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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thiomorpholines
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Accession:CHEBI:36393 term browser browse the term


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prinomastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMP13 matrix metallopeptidase 13 decreases activity EXP prinomastat results in decreased activity of MMP13 protein CTD PMID:17267227 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 decreases activity EXP prinomastat results in decreased activity of MMP2 protein CTD PMID:17267227 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 decreases activity EXP prinomastat results in decreased activity of MMP3 protein CTD PMID:17267227 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP8 matrix metallopeptidase 8 decreases activity EXP prinomastat results in decreased activity of MMP8 protein CTD PMID:17267227 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP prinomastat inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    chemical entity 26020
      atom 26016
        nonmetal atom 25505
          nitrogen atom 22541
            nitrogen molecular entity 22541
              organonitrogen compound 21934
                organonitrogen heterocyclic compound 20345
                  thiazinane 5
                    thiomorpholines 5
                      (3R)-3-(fluoromethyl)-7-(thiomorpholin-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline 0
                      (3S)-4-\{[4-(but-2-ynyloxy)phenyl]sulfonyl\}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                      1-adamantyl(1,4-thiazinan-4-yl)methanone 0
                      4-(\{4-[(4-aminobut-2-ynyl)oxy]phenyl\}sulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                      4-methyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}pentanoic acid 0
                      6-chloro-N-[(2S)-3-(1,1-dioxidothiomorpholin-4-yl)-3-oxo-2-\{[(1-pyridin-4-ylpiperidin-4-yl)methyl]amino\}propyl]naphthalene-2-sulfonamide 0
                      Ethyl N-(1,4-thiazinan-4-ylcarbothioyl)carbamate 0
                      ethyl 3-phenyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}propionate 0
                      prinomastat 5
                      thiomorpholine 0
                      thiomorpholine-3,5-dicarboxylic acid + 0
                      thiomorpholine-3-carboxylate 0
                      thiomorpholinemonocarboxylic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            organic molecule 25228
                              organic cyclic compound 24281
                                organic heterocyclic compound 22324
                                  organic heteromonocyclic compound 19228
                                    thiazinane 5
                                      thiomorpholines 5
                                        (3R)-3-(fluoromethyl)-7-(thiomorpholin-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline 0
                                        (3S)-4-\{[4-(but-2-ynyloxy)phenyl]sulfonyl\}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                                        1-adamantyl(1,4-thiazinan-4-yl)methanone 0
                                        4-(\{4-[(4-aminobut-2-ynyl)oxy]phenyl\}sulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                                        4-methyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}pentanoic acid 0
                                        6-chloro-N-[(2S)-3-(1,1-dioxidothiomorpholin-4-yl)-3-oxo-2-\{[(1-pyridin-4-ylpiperidin-4-yl)methyl]amino\}propyl]naphthalene-2-sulfonamide 0
                                        Ethyl N-(1,4-thiazinan-4-ylcarbothioyl)carbamate 0
                                        ethyl 3-phenyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}propionate 0
                                        prinomastat 5
                                        thiomorpholine 0
                                        thiomorpholine-3,5-dicarboxylic acid + 0
                                        thiomorpholine-3-carboxylate 0
                                        thiomorpholinemonocarboxylic acid + 0
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