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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:thiomorpholines
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Accession:CHEBI:36393 term browser browse the term


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prinomastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp13 matrix metallopeptidase 13 decreases activity ISO prinomastat results in decreased activity of MMP13 protein CTD PMID:17267227 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO prinomastat results in decreased activity of MMP2 protein CTD PMID:17267227 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases activity ISO prinomastat results in decreased activity of MMP3 protein CTD PMID:17267227 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp8 matrix metallopeptidase 8 decreases activity ISO prinomastat results in decreased activity of MMP8 protein CTD PMID:17267227 NCBI chr 8:5,768,808...5,777,741
Ensembl chr 8:5,768,811...5,778,702
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO prinomastat inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19772
    chemical entity 19771
      atom 19767
        nonmetal atom 19641
          nitrogen atom 18537
            nitrogen molecular entity 18537
              organonitrogen compound 18307
                organonitrogen heterocyclic compound 17458
                  thiazinane 5
                    thiomorpholines 5
                      (3R)-3-(fluoromethyl)-7-(thiomorpholin-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline 0
                      (3S)-4-\{[4-(but-2-ynyloxy)phenyl]sulfonyl\}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                      4-(\{4-[(4-aminobut-2-ynyl)oxy]phenyl\}sulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                      4-methyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}pentanoic acid 0
                      6-chloro-N-[(2S)-3-(1,1-dioxidothiomorpholin-4-yl)-3-oxo-2-\{[(1-pyridin-4-ylpiperidin-4-yl)methyl]amino\}propyl]naphthalene-2-sulfonamide 0
                      ethyl 3-phenyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}propionate 0
                      prinomastat 5
                      thiomorpholine 0
                      thiomorpholine-3,5-dicarboxylic acid + 0
                      thiomorpholine-3-carboxylate 0
                      thiomorpholinemonocarboxylic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19772
    subatomic particle 19767
      composite particle 19767
        hadron 19767
          baryon 19767
            nucleon 19767
              atomic nucleus 19767
                atom 19767
                  main group element atom 19654
                    p-block element atom 19654
                      carbon group element atom 19550
                        carbon atom 19539
                          organic molecular entity 19539
                            organic molecule 19461
                              organic cyclic compound 19231
                                organic heterocyclic compound 18406
                                  organic heteromonocyclic compound 16438
                                    thiazinane 5
                                      thiomorpholines 5
                                        (3R)-3-(fluoromethyl)-7-(thiomorpholin-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline 0
                                        (3S)-4-\{[4-(but-2-ynyloxy)phenyl]sulfonyl\}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                                        4-(\{4-[(4-aminobut-2-ynyl)oxy]phenyl\}sulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide 0
                                        4-methyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}pentanoic acid 0
                                        6-chloro-N-[(2S)-3-(1,1-dioxidothiomorpholin-4-yl)-3-oxo-2-\{[(1-pyridin-4-ylpiperidin-4-yl)methyl]amino\}propyl]naphthalene-2-sulfonamide 0
                                        ethyl 3-phenyl-2-\{[4-(toluene-4-sulfonyl)thiomorpholine-3-carbonyl]amino\}propionate 0
                                        prinomastat 5
                                        thiomorpholine 0
                                        thiomorpholine-3,5-dicarboxylic acid + 0
                                        thiomorpholine-3-carboxylate 0
                                        thiomorpholinemonocarboxylic acid + 0
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