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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:saturated organic heteromonocyclic parent
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Accession:CHEBI:36389 term browser browse the term
Synonyms:related_synonym: saturated heteromonocyclic parent hydride;   saturated heteromonocyclic parent hydrides;   saturated organic heteromonocyclic parents

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1,3-thiazolidine-2,4-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL6 interleukin 6 multiple interactions EXP 2,4-thiazolidinedione inhibits the reaction [Linoleic Acid results in increased expression of IL6 protein]; [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of IL6 mRNA]] CTD PMID:14519784 PMID:15226458 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP 2,4-thiazolidinedione binds to and results in increased activity of PPARG protein CTD PMID:14519784 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP 2,4-thiazolidinedione inhibits the reaction [Linoleic Acid results in increased activity of RELA protein] CTD PMID:14519784 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP [2,4-thiazolidinedione co-treated with Zinc] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of TNF protein]; [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of IL6 mRNA]]; [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA]] CTD PMID:15226458 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP [Zinc co-treated with 2,4-thiazolidinedione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein results in increased expression of VCAM1 mRNA]] CTD PMID:15226458 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,908...117,511,226 		JBrowse link
deoxynivalenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTB actin beta increases expression EXP deoxynivalenol results in increased expression of ACTB mRNA CTD PMID:26417708 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression
decreases phosphorylation		 EXP deoxynivalenol results in decreased expression of AKT1 mRNA; deoxynivalenol results in decreased expression of AKT1 protein
deoxynivalenol results in decreased phosphorylation of AKT1 protein		 CTD PMID:16099139 PMID:32229166
G ALB albumin decreases expression EXP deoxynivalenol results in decreased expression of ALB protein CTD PMID:19477247 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,718,304 		JBrowse link
G AXIN2 axin 2 increases expression EXP deoxynivalenol results in increased expression of AXIN2 protein CTD PMID:30690062 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,293...12,343,200 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions		 EXP deoxynivalenol results in decreased expression of BCL2 mRNA; deoxynivalenol results in decreased expression of BCL2 protein
[Acetylcysteine co-treated with fumonisin B1 co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA; [fumonisin B1 co-treated with Zearalenone co-treated with deoxynivalenol] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; fumonisin B1 inhibits the reaction [Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]]; Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]]		 CTD PMID:25701311 PMID:29109043 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger decreases expression EXP deoxynivalenol results in decreased expression of BMI1 protein CTD PMID:30690062 NCBI chr10:52,586,089...52,596,154 JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases activity		 EXP [fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 protein; [fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]
deoxynivalenol results in increased expression of CASP3 mRNA; deoxynivalenol results in increased expression of CASP3 protein
deoxynivalenol results in increased activity of CASP3 protein		 CTD PMID:20937367 PMID:24394488 PMID:29109043 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions
decreases expression		 EXP deoxynivalenol results in increased expression of CCL2 mRNA
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA]
deoxynivalenol results in decreased expression of CCL2 mRNA		 CTD PMID:23688591 PMID:30708112 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 multiple interactions
increases expression		 EXP [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CCL20 mRNA]
deoxynivalenol results in increased expression of CCL20 mRNA		 CTD PMID:23326479 PMID:30708112 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCND1 cyclin D1 decreases expression EXP deoxynivalenol results in decreased expression of CCND1 protein CTD PMID:30690062 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 increases expression EXP deoxynivalenol results in increased expression of CCR6 mRNA CTD PMID:23326479 NCBI chr 1:2,016,600...2,034,172
Ensembl chr 1:2,018,608...2,019,821 		JBrowse link
G CLDN3 claudin 3 decreases expression EXP deoxynivalenol analog results in decreased expression of CLDN3 protein; deoxynivalenol results in decreased expression of CLDN3 protein CTD PMID:19289138 PMID:22859312 NCBI chr 3:11,019,073...11,020,102
Ensembl chr 3:11,019,295...11,019,960 		JBrowse link
G CLDN4 claudin 4 decreases expression EXP deoxynivalenol analog results in decreased expression of CLDN4 protein; deoxynivalenol results in decreased expression of CLDN4 protein CTD PMID:19289138 PMID:22859312 NCBI chr 3:11,039,711...11,053,930
Ensembl chr 3:11,039,706...11,053,925 		JBrowse link
G CRP C-reactive protein, pentraxin-related decreases expression EXP deoxynivalenol results in decreased expression of CRP protein CTD PMID:25701311 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236 		JBrowse link
G CTNNB1 catenin beta 1 decreases expression EXP deoxynivalenol results in decreased expression of CTNNB1 protein CTD PMID:30690062 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,137,173...25,208,311 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 increases expression EXP deoxynivalenol results in increased expression of CX3CL1 mRNA CTD PMID:23326479 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases expression EXP deoxynivalenol results in increased expression of CXCL10 mRNA CTD PMID:25701311 NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
decreases expression
multiple interactions		 EXP deoxynivalenol results in increased expression of CXCL8 mRNA; deoxynivalenol results in increased expression of CXCL8 protein
deoxynivalenol results in decreased expression of CXCL8 protein
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of CXCL8 mRNA]; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA]; fumonisin B1 promotes the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CXCL8 mRNA]		 CTD PMID:23326479 PMID:23688591 PMID:25701311 PMID:26417708 PMID:27915442 PMID:30708112 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA] CTD PMID:29109043 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions EXP deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA] CTD PMID:17656051 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 multiple interactions EXP deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] CTD PMID:17656051 NCBI chr 1:120,596,235...120,627,806
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G DEFB1 defensin beta 1 decreases expression EXP deoxynivalenol results in decreased expression of DEFB1 mRNA CTD PMID:25701311
G DNMT3A DNA methyltransferase 3 alpha increases expression EXP deoxynivalenol results in increased expression of DNMT3A mRNA CTD PMID:26988607 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,609,139 		JBrowse link
G EIF4E eukaryotic translation initiation factor 4E decreases phosphorylation EXP deoxynivalenol results in decreased phosphorylation of EIF4E protein CTD PMID:16099139 NCBI chr 8:121,409,633...121,464,467
Ensembl chr 8:121,409,731...121,466,899 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression EXP deoxynivalenol results in decreased expression of EIF4EBP1 protein modified form CTD PMID:16099139 NCBI chr15:48,423,001...48,443,373
Ensembl chr15:48,422,816...48,443,399 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit increases expression EXP deoxynivalenol results in increased expression of EZH2 mRNA CTD PMID:26988607 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,384,995...109,450,941 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] CTD PMID:17656051 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274 		JBrowse link
G GPX2 glutathione peroxidase 2 increases expression EXP deoxynivalenol results in increased expression of GPX2 mRNA CTD PMID:25701311 NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,369...89,011,620 		JBrowse link
G GPX3 glutathione peroxidase 3 decreases expression EXP deoxynivalenol results in decreased expression of GPX3 mRNA CTD PMID:25701311 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026 		JBrowse link
G GPX4 glutathione peroxidase 4 decreases expression EXP deoxynivalenol results in decreased expression of GPX4 mRNA CTD PMID:25701311 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,886 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases expression EXP deoxynivalenol results in increased expression of GSK3B protein CTD PMID:30690062 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,574 		JBrowse link
G GSR glutathione-disulfide reductase decreases activity
multiple interactions		 EXP deoxynivalenol results in decreased activity of GSR protein
Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]		 CTD PMID:29109043 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,989 		JBrowse link
G IFNB1 interferon beta 1 increases expression EXP deoxynivalenol results in increased expression of IFNB1 mRNA CTD PMID:24394488 NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495 		JBrowse link
G IFNG interferon gamma increases expression
decreases expression
multiple interactions		 EXP deoxynivalenol results in increased expression of IFNG mRNA
deoxynivalenol results in decreased expression of IFNG mRNA
[Zearalenone co-treated with deoxynivalenol] results in decreased expression of IFNG mRNA		 CTD PMID:18296887 PMID:18329193 PMID:25701311 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol affects the reaction [IGF1 protein results in increased abundance of Estradiol]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] CTD PMID:17656051 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037 		JBrowse link
G IL10 interleukin 10 increases expression
multiple interactions		 EXP deoxynivalenol results in increased expression of IL10 mRNA
deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 mRNA]		 CTD PMID:19027837 PMID:19607891 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711 		JBrowse link
G IL17A interleukin 17A multiple interactions
increases expression		 EXP [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein; deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL17A mRNA]; fumonisin B1 inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein]; fumonisin B1 metabolite inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of IL17A protein]
deoxynivalenol results in increased expression of IL17A mRNA; deoxynivalenol results in increased expression of IL17A protein		 CTD PMID:23326479 PMID:27915442 PMID:30708112 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions
decreases expression		 EXP deoxynivalenol results in increased expression of IL1A mRNA; deoxynivalenol results in increased expression of IL1A protein
[deoxynivalenol co-treated with fumonisin B1] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]
deoxynivalenol results in decreased expression of IL1A mRNA		 CTD PMID:23326479 PMID:23688591 PMID:27915442 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL1B2 interleukin 1, beta 2 increases expression
multiple interactions		 EXP deoxynivalenol results in increased expression of IL1B2 mRNA
deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1B2 mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1B2 mRNA]		 CTD PMID:27915442
G IL2 interleukin 2 multiple interactions EXP [Zearalenone co-treated with deoxynivalenol] results in decreased expression of IL2 mRNA CTD PMID:18296887 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL21 interleukin 21 increases expression EXP deoxynivalenol results in increased expression of IL21 mRNA CTD PMID:23326479 NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,530,949...101,540,738 		JBrowse link
G IL22 interleukin 22 multiple interactions
increases expression		 EXP deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL22 mRNA]
deoxynivalenol results in increased expression of IL22 mRNA		 CTD PMID:23326479 PMID:27915442 NCBI chr 5:32,599,522...32,604,507
Ensembl chr 5:32,599,301...32,604,736 		JBrowse link
G IL23A interleukin 23 subunit alpha increases expression EXP deoxynivalenol results in increased expression of IL23A mRNA CTD PMID:23326479 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G IL4 interleukin 4 increases expression EXP deoxynivalenol results in increased expression of IL4 mRNA CTD PMID:25701311 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression		 EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol] results in decreased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; deoxynivalenol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; deoxynivalenol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]
deoxynivalenol results in increased expression of IL6 mRNA; deoxynivalenol results in increased expression of IL6 protein		 CTD PMID:19027837 PMID:19607891 PMID:23326479 PMID:23688591 PMID:24394488 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 increases expression EXP deoxynivalenol results in increased expression of LAMP2 mRNA CTD PMID:26988607 NCBI chr  X:98,586,718...98,623,939
Ensembl chr  X:98,582,059...98,623,908 		JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions
increases expression		 EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA]
deoxynivalenol results in increased expression of IL1B mRNA		 CTD PMID:19027837 PMID:23326479 PMID:23688591
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha increases expression EXP deoxynivalenol results in increased expression of MAP1LC3A mRNA CTD PMID:32229166 PMID:32302720 NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression EXP deoxynivalenol results in increased expression of MAP1LC3B mRNA CTD PMID:26988607 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,077 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
decreases expression
increases activity		 EXP deoxynivalenol analog results in increased phosphorylation of MAPK1 protein; deoxynivalenol results in increased phosphorylation of MAPK1 protein
deoxynivalenol results in decreased expression of MAPK1 protein modified form
deoxynivalenol results in increased activity of MAPK1 protein		 CTD PMID:19674540 PMID:22859312 PMID:26988607 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases expression
increases activity
increases phosphorylation		 EXP deoxynivalenol results in decreased expression of MAPK3 protein modified form
deoxynivalenol results in increased activity of MAPK3 protein
deoxynivalenol analog results in increased phosphorylation of MAPK3 protein; deoxynivalenol results in increased phosphorylation of MAPK3 protein		 CTD PMID:19674540 PMID:22859312 PMID:26988607 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MFN1 mitofusin 1 decreases expression EXP deoxynivalenol results in decreased expression of MFN1 protein CTD PMID:32302720 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481 		JBrowse link
G MFN2 mitofusin 2 decreases expression EXP deoxynivalenol results in decreased expression of MFN2 protein CTD PMID:32302720 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,026,722...72,056,439 		JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases expression
decreases phosphorylation		 EXP deoxynivalenol results in decreased expression of MTOR mRNA
deoxynivalenol results in decreased phosphorylation of MTOR protein		 CTD PMID:26988607 PMID:32229166 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP deoxynivalenol results in decreased expression of MYC protein CTD PMID:30690062 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,119...12,461,078 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression EXP deoxynivalenol results in increased expression of NOS2 mRNA CTD PMID:25701311 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111 		JBrowse link
G OCLN occludin decreases expression EXP deoxynivalenol results in decreased expression of OCLN mRNA CTD PMID:25701311 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,498...47,654,033 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase decreases expression EXP deoxynivalenol results in decreased expression of OPA1 protein CTD PMID:32302720 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,823...130,719,083 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression EXP deoxynivalenol results in decreased expression of PCNA protein CTD PMID:30690062 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,125,814...14,185,276 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma decreases expression EXP deoxynivalenol results in decreased expression of PIK3CG mRNA CTD PMID:32229166 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases expression
decreases phosphorylation		 EXP deoxynivalenol results in decreased expression of RPS6KB1 mRNA
deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein		 CTD PMID:32229166 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 increases expression EXP deoxynivalenol results in increased expression of SETDB1 mRNA CTD PMID:26988607 NCBI chr 4:98,259,801...98,293,238
Ensembl chr 4:98,260,373...98,293,096 		JBrowse link
G SQSTM1 sequestosome 1 increases expression EXP deoxynivalenol results in increased expression of SQSTM1 mRNA CTD PMID:32302720 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,768...78,784,256 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression EXP deoxynivalenol results in increased expression of STAT3 mRNA CTD PMID:23326479 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993 		JBrowse link
G SUV39H2 suppressor of variegation 3-9 homolog 2 increases expression EXP deoxynivalenol results in increased expression of SUV39H2 mRNA CTD PMID:26988607 NCBI chr10:46,874,606...46,900,058
Ensembl chr10:46,862,584...46,900,040 		JBrowse link
G TFF1 trefoil factor 1 affects expression EXP deoxynivalenol affects the expression of TFF1 mRNA CTD PMID:30854615 NCBI chr13:205,687,558...205,691,512 JBrowse link
G TFF2 trefoil factor 2 decreases expression EXP deoxynivalenol results in decreased expression of TFF2 mRNA CTD PMID:30854615 NCBI chr13:205,669,014...205,672,319
Ensembl chr13:205,669,014...205,672,324 		JBrowse link
G TFF3 trefoil factor 3 decreases expression EXP deoxynivalenol results in decreased expression of TFF3 mRNA CTD PMID:30854615 NCBI chr13:205,641,038...205,644,333
Ensembl chr13:205,642,374...205,644,334 		JBrowse link
G TGFB1 transforming growth factor beta 1 decreases expression
increases expression		 EXP deoxynivalenol results in decreased expression of TGFB1 mRNA
deoxynivalenol results in increased expression of TGFB1 mRNA		 CTD PMID:18329193 PMID:23326479 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048 		JBrowse link
G TJP1 tight junction protein 1 increases expression
decreases expression		 EXP deoxynivalenol results in increased expression of TJP1 mRNA
deoxynivalenol results in decreased expression of TJP1 protein		 CTD PMID:20937367 PMID:26417708 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,368...145,195,836 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression		 EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF protein; [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA; [Zearalenone co-treated with deoxynivalenol] results in decreased expression of TNF mRNA; deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA] CTD PMID:18296887 PMID:19027837 PMID:19607891 PMID:23326479 PMID:23688591 PMID:24394488 PMID:30708112 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA; Acetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]; fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA] CTD PMID:29109043 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819 		JBrowse link
G VIM vimentin decreases expression EXP deoxynivalenol results in decreased expression of VIM mRNA CTD PMID:25701311 NCBI chr10:43,516,441...43,526,172
Ensembl chr10:43,517,307...43,526,172 		JBrowse link
G XCR1 X-C motif chemokine receptor 1 increases expression EXP deoxynivalenol results in increased expression of XCR1 mRNA CTD PMID:23326479 NCBI chr13:29,150,376...29,233,802
Ensembl chr13:29,150,379...29,159,637 		JBrowse link
eplerenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions EXP Eplerenone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183 		JBrowse link
Nivalenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions		 EXP nivalenol results in increased expression of CCL2 mRNA
[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of CCL2 mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA		 CTD PMID:23688591 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions		 EXP nivalenol results in increased expression of CXCL8 mRNA
[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of CXCL8 mRNA]		 CTD PMID:23688591 PMID:27915442 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G IL17A interleukin 17A multiple interactions
increases expression		 EXP deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL17A mRNA] CTD PMID:27915442 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression
decreases expression		 EXP [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]
nivalenol results in decreased expression of IL1A mRNA		 CTD PMID:23688591 PMID:27915442 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL1B2 interleukin 1, beta 2 multiple interactions
increases expression		 EXP deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1B2 mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1B2 mRNA] CTD PMID:27915442
G IL22 interleukin 22 multiple interactions
increases expression		 EXP deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL22 mRNA] CTD PMID:27915442 NCBI chr 5:32,599,522...32,604,507
Ensembl chr 5:32,599,301...32,604,736 		JBrowse link
G IL6 interleukin 6 increases expression
decreases expression
multiple interactions		 EXP nivalenol results in increased expression of IL6 mRNA
nivalenol results in decreased expression of IL6 mRNA
[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol] results in decreased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL6 mRNA; [nivalenol co-treated with fumonisin B1] results in decreased expression of IL6 mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA		 CTD PMID:23688591 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression
multiple interactions		 EXP nivalenol results in increased expression of IL1B mRNA
[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1B mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA		 CTD PMID:23688591
G TNF tumor necrosis factor increases expression
multiple interactions		 EXP nivalenol results in increased expression of TNF mRNA
[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of TNF mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA		 CTD PMID:23688591 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655 		JBrowse link
troleandomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 multiple interactions EXP Troleandomycin inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased oxidation of Nifedipine] CTD PMID:20863320 NCBI chr 3:6,738,502...6,778,121 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 874
    chemical entity 874
      group 837
        polyatomic entity 837
          molecule 735
            cyclic compound 644
              heterocyclic compound 361
                heteromonocyclic compound 186
                  organic heteromonocyclic compound 186
                    saturated organic heteromonocyclic parent 79
                      1,3,5,7-tetrazocane 0
                      1,3,5-thiadiazinane 0
                      1,3,5-trioxane 0
                      1,4,7,10-tetraazacyclododecane + 0
                      1,4,7,10-tetrathiacyclododecane 0
                      1,4,7-triazonane 0
                      1,4,7-trithionane 0
                      1,4,8,11-tetraazacyclotetradecane + 0
                      12-crown-4 0
                      15-crown-5 0
                      18-crown-6 0
                      9-crown-3 0
                      arsolane 0
                      azepane 0
                      azetidine + 0
                      aziridine + 0
                      azocane + 0
                      dioxane + 0
                      dithianes + 0
                      dithiolane + 0
                      imidazolidine + 0
                      morpholine + 0
                      oxane + 0
                      oxathiiocane + 0
                      oxazolidine + 0
                      oxepane + 0
                      oxetane + 0
                      oxirane + 76
                      oxolane + 0
                      pentathiepane + 0
                      phospholane 0
                      piperazine 0
                      piperidine + 0
                      pyrazolidine 0
                      pyrrolidine + 0
                      tetrahydrothiophene + 0
                      thiazolidine + 5
                      thiirane 0
                      thiomorpholine 0
                      triazinane + 0
                      trithiane + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 874
    subatomic particle 859
      composite particle 859
        hadron 859
          baryon 859
            nucleon 859
              atomic nucleus 859
                atom 859
                  main group element atom 849
                    p-block element atom 846
                      carbon group element atom 822
                        carbon atom 821
                          organic molecular entity 821
                            organic molecule 734
                              organic cyclic compound 644
                                organic heterocyclic compound 361
                                  organic heteromonocyclic compound 186
                                    saturated organic heteromonocyclic parent 79
                                      1,3,5,7-tetrazocane 0
                                      1,3,5-thiadiazinane 0
                                      1,3,5-trioxane 0
                                      1,4,7,10-tetraazacyclododecane + 0
                                      1,4,7,10-tetrathiacyclododecane 0
                                      1,4,7-triazonane 0
                                      1,4,7-trithionane 0
                                      1,4,8,11-tetraazacyclotetradecane + 0
                                      12-crown-4 0
                                      15-crown-5 0
                                      18-crown-6 0
                                      9-crown-3 0
                                      arsolane 0
                                      azepane 0
                                      azetidine + 0
                                      aziridine + 0
                                      azocane + 0
                                      dioxane + 0
                                      dithianes + 0
                                      dithiolane + 0
                                      imidazolidine + 0
                                      morpholine + 0
                                      oxane + 0
                                      oxathiiocane + 0
                                      oxazolidine + 0
                                      oxepane + 0
                                      oxetane + 0
                                      oxirane + 76
                                      oxolane + 0
                                      pentathiepane + 0
                                      phospholane 0
                                      piperazine 0
                                      piperidine + 0
                                      pyrazolidine 0
                                      pyrrolidine + 0
                                      tetrahydrothiophene + 0
                                      thiazolidine + 5
                                      thiirane 0
                                      thiomorpholine 0
                                      triazinane + 0
                                      trithiane + 0
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