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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:36332 term browser browse the term
Definition:Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).
Synonyms:exact_synonym: 6-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
 related_synonym: 6-(3,4-dihydroxystyryl)-4-hydroxy-2-pyrone;   6-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one;   Formula=C13H10O5;   InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+;   InChIKey=SGJNQVTUYXCBKH-HNQUOIGGSA-N;   SMILES=C=1C(OC(=CC1O)/C=C/C2=CC=C(C(=C2)O)O)=O
 xref: Beilstein:1288087;   CAS:555-55-5
 xref_mesh: MESH:C007946

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hispidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp9 caspase 9 multiple interactions
increases activity
EXP hispidin inhibits the reaction [Doxorubicin results in increased activity of CASP9 protein]
hispidin results in increased activity of CASP9 protein
CTD PMID:26318906 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions EXP hispidin inhibits the reaction [Doxorubicin results in increased expression of and results in decreased phosphorylation of and affects the localization of SHC1 protein] CTD PMID:26318906 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO hispidin inhibits the reaction [Cyclosporine results in increased phosphorylation of and results in increased activity of SMAD2 protein] CTD PMID:22155090 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link

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  CHEBI ontology 19795
    role 19746
      chemical role 19316
        antioxidant 14437
          hispidin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic group 18713
                              organic divalent group 18697
                                organodiyl group 18697
                                  carbonyl group 18646
                                    carbonyl compound 18646
                                      carboxylic ester 15881
                                        lactone 11255
                                          delta-lactone 3883
                                            2-pyranones 756
                                              hispidin 3
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