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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:36332 term browser browse the term
Definition:Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).
Synonyms:exact_synonym: 6-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
 related_synonym: 6-(3,4-dihydroxystyryl)-4-hydroxy-2-pyrone;   6-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one;   Formula=C13H10O5;   InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+;   InChIKey=SGJNQVTUYXCBKH-HNQUOIGGSA-N;   SMILES=C=1C(OC(=CC1O)/C=C/C2=CC=C(C(=C2)O)O)=O
 xref: Beilstein:1288087;   CAS:555-55-5
 xref_mesh: MESH:C007946

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hispidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp9 caspase 9 multiple interactions
increases activity
EXP hispidin inhibits the reaction [Doxorubicin results in increased activity of CASP9 protein]
hispidin results in increased activity of CASP9 protein
CTD PMID:26318906 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions EXP hispidin inhibits the reaction [Doxorubicin results in increased expression of and results in decreased phosphorylation of and affects the localization of SHC1 protein] CTD PMID:26318906 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO hispidin inhibits the reaction [Cyclosporine results in increased phosphorylation of and results in increased activity of SMAD2 protein] CTD PMID:22155090 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link

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  CHEBI ontology 19770
    role 19720
      chemical role 19260
        antioxidant 14254
          hispidin 3
Path 2
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  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      carboxylic ester 15492
                                        lactone 9708
                                          delta-lactone 3824
                                            2-pyranones 745
                                              hispidin 3
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