CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: octadecanoid
Accession: CHEBI:36326
browse the term
Definition: Unsaturated C18 fatty acids and skeletally related compounds.
Synonyms: related_synonym: octadecanoids
cyclic_relationship: is_conjugate_acid_of CHEBI:131860
G
Cat
catalase
increases expression
ISO
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAT protein
CTD
PMID:10946007
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
G
Cav1
caveolin 1
increases expression
ISO
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAV1 mRNA
CTD
PMID:27257344
NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions
EXP
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein
CTD
PMID:22135674
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
G
Egr1
early growth response 1
multiple interactions
EXP
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein
CTD
PMID:22135674
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
G
Ppara
peroxisome proliferator activated receptor alpha
increases expression
EXP
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARA protein
CTD
PMID:22135674
NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
G
Pparg
peroxisome proliferator-activated receptor gamma
increases expression
EXP
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARG protein
CTD
PMID:22135674
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
G
Gsta1
glutathione S-transferase alpha 1
affects metabolic processing
ISO
GSTA1 protein affects the metabolism of 13-oxo-9,11-octadecadienoic acid
CTD
PMID:12031293
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
G
Gsta4
glutathione S-transferase alpha 4
affects metabolic processing
ISO
GSTA4 protein affects the metabolism of 13-oxo-9,11-octadecadienoic acid
CTD
PMID:12031293
NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
G
Pparg
peroxisome proliferator-activated receptor gamma
increases expression
ISO
9-hydroxy-10,12-octadecadienoic acid results in increased expression of PPARG
CTD
PMID:16647253
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
G
Agt
angiotensinogen
multiple interactions increases lipidation
ISO
Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form]
CTD
PMID:26111765
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
G
Cygb
cytoglobin
increases metabolic processing
EXP
CYGB protein results in increased metabolism of linoleic acid hydroperoxide
CTD
PMID:11320098
NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
G
Gpx1
glutathione peroxidase 1
increases reduction
ISO
GPX1 protein results in increased reduction of linoleic acid hydroperoxide
CTD
PMID:8428933
NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
G
Gpx2
glutathione peroxidase 2
increases reduction
ISO
GPX2 protein results in increased reduction of linoleic acid hydroperoxide
CTD
PMID:8428933
NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19761
chemical entity
19761
atom
19759
nonmetal atom
19641
carbon atom
19559
organic molecular entity
19559
lipid
17483
fatty acid
16011
unsaturated fatty acid
949
octadecanoid
12
(10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid
0
(6E,8Z)-5-oxooctadecadienoic acid
0
(9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoic acid
0
(9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid
0
11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid
0
12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid
0
5(S),8(R)-DiHODE
0
7(S),8(S)-DiHODE
0
8(R)-HPODE
0
9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid
0
HODE +
3
HPODE +
10
Jasmonate derivatives +
0
TriHOME +
0
hydroperoxyoctadecatrienoic acid +
0
hydroperoxyoctadecenoic acid +
0
octadecatetraenoic acid +
0
Path 2
CHEBI ontology
19761
subatomic particle
19759
composite particle
19759
hadron
19759
baryon
19759
nucleon
19759
atomic nucleus
19759
atom
19759
main group element atom
19653
p-block element atom
19653
carbon group element atom
19569
carbon atom
19559
organic molecular entity
19559
organic group
18593
organic divalent group
18584
organodiyl group
18584
carbonyl group
18499
carbonyl compound
18499
carboxylic acid
18151
monocarboxylic acid
17523
fatty acid
16011
unsaturated fatty acid
949
octadecanoid
12
(10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid
0
(6E,8Z)-5-oxooctadecadienoic acid
0
(9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoic acid
0
(9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid
0
11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid
0
12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid
0
5(S),8(R)-DiHODE
0
7(S),8(S)-DiHODE
0
8(R)-HPODE
0
9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid
0
HODE +
3
HPODE +
10
Jasmonate derivatives +
0
TriHOME +
0
hydroperoxyoctadecatrienoic acid +
0
hydroperoxyoctadecenoic acid +
0
octadecatetraenoic acid +
0