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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:octadecanoid
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Accession:CHEBI:36326 term browser browse the term
Definition:Unsaturated C18 fatty acids and skeletally related compounds.
Synonyms:related_synonym: octadecanoids
 cyclic_relationship: is_conjugate_acid_of CHEBI:131860

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13-HPODE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases expression ISO 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAT protein CTD PMID:10946007 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cav1 caveolin 1 increases expression ISO 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAV1 mRNA CTD PMID:27257344 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein CTD PMID:22135674 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein CTD PMID:22135674 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARA protein CTD PMID:22135674 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARG protein CTD PMID:22135674 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
13-oxo-9,11-octadecadienoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 affects metabolic processing ISO GSTA1 protein affects the metabolism of 13-oxo-9,11-octadecadienoic acid CTD PMID:12031293 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 affects metabolic processing ISO GSTA4 protein affects the metabolism of 13-oxo-9,11-octadecadienoic acid CTD PMID:12031293 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879 		JBrowse link
9-HODE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO 9-hydroxy-10,12-octadecadienoic acid results in increased expression of PPARG CTD PMID:16647253 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
linoleic acid hydroperoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions
increases lipidation		 ISO Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form] CTD PMID:26111765 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Cygb cytoglobin increases metabolic processing EXP CYGB protein results in increased metabolism of linoleic acid hydroperoxide CTD PMID:11320098 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases reduction ISO GPX1 protein results in increased reduction of linoleic acid hydroperoxide CTD PMID:8428933 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases reduction ISO GPX2 protein results in increased reduction of linoleic acid hydroperoxide CTD PMID:8428933 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    chemical entity 19761
      atom 19759
        nonmetal atom 19641
          carbon atom 19559
            organic molecular entity 19559
              lipid 17483
                fatty acid 16011
                  unsaturated fatty acid 949
                    octadecanoid 12
                      (10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid 0
                      (6E,8Z)-5-oxooctadecadienoic acid 0
                      (9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoic acid 0
                      (9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid 0
                      11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid 0
                      12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid 0
                      5(S),8(R)-DiHODE 0
                      7(S),8(S)-DiHODE 0
                      8(R)-HPODE 0
                      9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid 0
                      HODE + 3
                      HPODE + 10
                      Jasmonate derivatives + 0
                      TriHOME + 0
                      hydroperoxyoctadecatrienoic acid + 0
                      hydroperoxyoctadecenoic acid + 0
                      octadecatetraenoic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        monocarboxylic acid 17523
                                          fatty acid 16011
                                            unsaturated fatty acid 949
                                              octadecanoid 12
                                                (10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid 0
                                                (6E,8Z)-5-oxooctadecadienoic acid 0
                                                (9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoic acid 0
                                                (9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid 0
                                                11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid 0
                                                12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid 0
                                                5(S),8(R)-DiHODE 0
                                                7(S),8(S)-DiHODE 0
                                                8(R)-HPODE 0
                                                9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid 0
                                                HODE + 3
                                                HPODE + 10
                                                Jasmonate derivatives + 0
                                                TriHOME + 0
                                                hydroperoxyoctadecatrienoic acid + 0
                                                hydroperoxyoctadecenoic acid + 0
                                                octadecatetraenoic acid + 0
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