The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein
[EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] results in decreased abundance of [9,10,13-trihydroxy-11-octadecenoic acid binds to Ceramides]; [EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] which results in decreased chemical synthesis of 9,10,13-trihydroxy-11-octadecenoic acid
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in decreased phosphorylation of IRS1 protein cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of IRS1 mRNA]
[cis-9, trans-11-conjugated linoleic acid co-treated with trans-10,cis-12-conjugated linoleic acid] results in increased phosphorylation of and results in increased activity of MAP2K1 protein; cis-9, trans-11-conjugated linoleic acid results in increased phosphorylation of and results in increased activity of MAP2K1 protein
[cis-9, trans-11-conjugated linoleic acid co-treated with trans-10,cis-12-conjugated linoleic acid] results in increased phosphorylation of and results in increased activity of MAP2K3 protein; cis-9, trans-11-conjugated linoleic acid results in increased phosphorylation of and results in increased activity of MAP2K3 protein
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of PPARA mRNA; [trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of PPARA protein
cis-9, trans-11-conjugated linoleic acid results in increased expression of SLC2A4 protein cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of SLC2A4 mRNA]
cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of IRS1 mRNA]; cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of SLC2A4 mRNA] cis-9, trans-11-conjugated linoleic acid affects the expression of TNF mRNA
[caffeic acid results in decreased activity of ALOX15 protein] which results in decreased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [caffeic acid results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; [Masoprocol results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [Sulindac results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [Vorinostat results in increased expression of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate LIPG gene mutant form affects the abundance of cholesteryl linoleate
Linoleic Acids, Conjugated results in increased expression of ADGRE1 mRNA; Linoleic Acids, Conjugated results in increased expression of ADGRE1 protein
[picolinic acid co-treated with Linoleic Acids, Conjugated] results in increased expression of ADIPOQ protein Linoleic Acids, Conjugated results in decreased expression of ADIPOQ protein
Linoleic Acids, Conjugated results in decreased expression of ADIPOR2 mRNA rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of ADIPOR2 mRNA]
Linoleic Acids, Conjugated results in decreased expression of CD36 mRNA rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of CD36 mRNA]
Linoleic Acids, Conjugated results in decreased phosphorylation of and results in decreased activity of ESR1 protein; Okadaic Acid inhibits the reaction [Linoleic Acids, Conjugated results in decreased phosphorylation of ESR1 protein]
Linoleic Acids, Conjugated results in increased activity of GCLC protein [Linoleic Acids, Conjugated results in increased activity of GCLC protein] which results in decreased susceptibility to tert-Butylhydroperoxide Linoleic Acids, Conjugated results in increased expression of GCLC mRNA
Linoleic Acids, Conjugated results in increased activity of GSK3B protein Linoleic Acids, Conjugated results in decreased phosphorylation of GSK3B protein
Linoleic Acids, Conjugated results in increased expression of IL1B mRNA resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of IL1B mRNA]
Linoleic Acids, Conjugated results in increased expression of IL6 mRNA; Linoleic Acids, Conjugated results in increased expression of IL6 protein Linoleic Acids, Conjugated results in decreased expression of IL6 protein [Chromium co-treated with Linoleic Acids, Conjugated] results in decreased expression of IL6 protein resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of IL6 mRNA]
Linoleic Acids, Conjugated results in decreased expression of INS protein Linoleic Acids, Conjugated results in increased susceptibility to INS protein
[Linoleic Acids, Conjugated co-treated with Chromium] results in decreased expression of LEP protein Linoleic Acids, Conjugated results in decreased expression of LEP protein Linoleic Acids, Conjugated results in increased expression of LEP protein
rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of LPL mRNA] Linoleic Acids, Conjugated results in increased activity of LPL protein
Linoleic Acids, Conjugated results in decreased activity of PPARG protein Linoleic Acids, Conjugated results in increased expression of PPARG mRNA Linoleic Acids, Conjugated results in increased expression of PPARG mRNA; Linoleic Acids, Conjugated results in increased expression of PPARG protein Linoleic Acids, Conjugated results in increased phosphorylation of and results in increased activity of PPARG protein; resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in decreased activity of PPARG protein]; resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased phosphorylation of and results in increased activity of PPARG protein] Linoleic Acids, Conjugated results in decreased expression of PPARG protein
Linoleic Acids, Conjugated results in increased expression of PTGS2 mRNA; Linoleic Acids, Conjugated results in increased expression of PTGS2 protein [Linoleic Acids, Conjugated results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprost; Resveratrol inhibits the reaction [[Linoleic Acids, Conjugated results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprost]; Resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of PTGS2 mRNA]
1-Butanol inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]]; Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Cholesterol]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Phospholipids]]; triacsin C inhibits the reaction [Linoleic Acid results in increased degradation of ABCA1 protein] Linoleic Acid analog results in decreased expression of ABCA1 mRNA Linoleic Acid results in increased expression of ABCA1 mRNA Linoleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] Linoleic Acid results in increased phosphorylation of ABCA1 protein
AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]
Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]
Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of BCL2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of BCL2 protein]
Linoleic Acid results in increased expression of CAT protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased activity of CAT protein]
CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein] CNR1 protein affects the susceptibility to Linoleic Acid
[Linoleic Acid co-treated with Testosterone] results in increased expression of FADS2 mRNA FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein] Linoleic Acid results in increased expression of FADS2 mRNA; Linoleic Acid results in increased expression of FADS2 protein
Linoleic Acid results in increased expression of GSTA1 mRNA NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA]
NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA] Linoleic Acid metabolite results in increased expression of HMOX1 mRNA; Linoleic Acid metabolite results in increased expression of HMOX1 protein
Linoleic Acid results in increased expression of IL1B protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL1B mRNA]
Linoleic Acid affects the expression of IL6 protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL6 mRNA] Linoleic Acid results in increased expression of IL6 mRNA Linoleic Acid results in increased secretion of IL6 protein
FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein]; TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein]
Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Linoleic Acid results in decreased expression of and results in decreased activity of MMP9 protein [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of MMP9 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of MMP9 protein] Linoleic Acid results in decreased expression of MMP9 mRNA
Linoleic Acid metabolite results in increased expression of NFE2L2 protein; Linoleic Acid results in increased expression of NFE2L2 mRNA; Linoleic Acid results in increased expression of NFE2L2 protein NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 protein]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA]
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of NOS2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of NOS2 protein]
PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]
Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] Linoleic Acid results in decreased activity of PON1 protein
[Bezafibrate binds to and results in increased activity of PPARA protein] which results in increased oxidation of Linoleic Acid; Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein]; Linoleic Acid binds to and results in increased activity of PPARA protein; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein]; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein] Linoleic Acid results in increased expression of PPARA mRNA PPARA protein affects the abundance of Linoleic Acid Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Linoleic Acid]; Linoleic Acid binds to and results in increased activity of PPARA protein Linoleic Acid results in increased expression of PPARA mRNA; Linoleic Acid results in increased expression of PPARA protein Linoleic Acid results in increased activity of PPARA protein Linoleic Acid binds to PPARA protein
Linoleic Acid binds to and results in increased activity of PPARB protein Linoleic Acid results in decreased expression of PPARD mRNA Linoleic Acid results in increased expression of PPARD mRNA Linoleic Acid results in increased activity of PPARD protein Linoleic Acid binds to PPARB protein
Linoleic Acid binds to PPARG protein Linoleic Acid binds to and results in increased activity of PPARG protein Linoleic Acid results in increased expression of PPARG mRNA resveratrol inhibits the reaction [Linoleic Acid results in increased expression of PPARG protein] Linoleic Acid results in increased activity of PPARG protein Linoleic Acid results in decreased expression of PPARG mRNA; Linoleic Acid results in decreased expression of PPARG protein
Linoleic Acid results in increased expression of PTGS2 mRNA Linoleic Acid inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 mRNA]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
[Linoleic Acid co-treated with Testosterone] results in increased expression of SCD mRNA Linoleic Acid results in increased expression of SCD mRNA; Linoleic Acid results in increased expression of SCD protein
Linoleic Acid results in decreased susceptibility to TNF protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of TNF mRNA]
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
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