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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hepoxilin A3
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Accession:CHEBI:36190 term browser browse the term
Definition:A hepoxilin having (5Z,9E,14Z) double bond stereochemistry, an 8-hydroxy substituent and an 11S,12S-epoxy group.
Synonyms:exact_synonym: (5Z,9E)-8-hydroxy-10-{(2S,3S)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl}deca-5,9-dienoic acid
 related_synonym: (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyeicosa-5,9,14-trienoic acid;   (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid;   8-EH-2;   8-Hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid;   8-hydroxy-10-(3-(2-octenyl)oxiranyl)-5,9-decadienoic acid;   8-hydroxy-11(S),12(S)-epoxy-eicosa- 5Z,9E,14Z-trienoic acid;   8-hydroxy-11S,12S-epoxy-5Z,14Z,9E-eicosatrienoic acid;   Formula=C20H32O4;   HXA3;   Hepoxilin A;   InChI=1S/C20H32O4/c1-2-3-4-5-6-10-13-18-19(24-18)16-15-17(21)12-9-7-8-11-14-20(22)23/h6-7,9-10,15-19,21H,2-5,8,11-14H2,1H3,(H,22,23)/b9-7-,10-6-,16-15+/t17?,18-,19-/m0/s1;   InChIKey=SGTUOBURCVMACZ-SEVPPISGSA-N;   SMILES=[H][C@@]1(C\\C=C/CCCCC)O[C@@]1([H])\\C=C\\C(O)C\\C=C/CCCC(O)=O
 alt_id: CHEBI:34783;   CHEBI:5670
 xref: CAS:85589-24-8;   CAS:94161-11-2;   KEGG:C14808;   LIPID_MAPS_instance:LMFA03090005
 xref_mesh: MESH:C038243
 xref: PMID:10100848;   PMID:10644052;   PMID:15123652;   PMID:8573089;   Reaxys:21024403
 cyclic_relationship: is_conjugate_acid_of CHEBI:132127


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hepoxilin A3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 increases export EXP ABCC2 protein results in increased export of 8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid CTD PMID:30102254 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biochemical role 21431
          metabolite 21379
            xenobiotic metabolite 15962
              human xenobiotic metabolite 15168
                hepoxilin A3 1
                  (8S)-hepoxilin A3 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            heteroorganic entity 21482
                              organochalcogen compound 20966
                                organooxygen compound 20806
                                  carbon oxoacid 19593
                                    carboxylic acid 19589
                                      monocarboxylic acid 18952
                                        fatty acid 17131
                                          unsaturated fatty acid 1091
                                            polyunsaturated fatty acid 832
                                              trienoic fatty acid 262
                                                fatty acid 20:3 1
                                                  (5Z,9E,14Z)-icosa-5,9,14-trienoic acid 1
                                                    hepoxilin A3 1
                                                      (8S)-hepoxilin A3 0
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