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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hepoxilin A3
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Accession:CHEBI:36190 term browser browse the term
Definition:A hepoxilin having (5Z,9E,14Z) double bond stereochemistry, an 8-hydroxy substituent and an 11S,12S-epoxy group.
Synonyms:exact_synonym: (5Z,9E)-8-hydroxy-10-{(2S,3S)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl}deca-5,9-dienoic acid
 related_synonym: (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyeicosa-5,9,14-trienoic acid;   (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid;   8-EH-2;   8-Hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid;   8-hydroxy-10-(3-(2-octenyl)oxiranyl)-5,9-decadienoic acid;   8-hydroxy-11(S),12(S)-epoxy-eicosa- 5Z,9E,14Z-trienoic acid;   8-hydroxy-11S,12S-epoxy-5Z,14Z,9E-eicosatrienoic acid;   Formula=C20H32O4;   HXA3;   Hepoxilin A;   InChI=1S/C20H32O4/c1-2-3-4-5-6-10-13-18-19(24-18)16-15-17(21)12-9-7-8-11-14-20(22)23/h6-7,9-10,15-19,21H,2-5,8,11-14H2,1H3,(H,22,23)/b9-7-,10-6-,16-15+/t17?,18-,19-/m0/s1;   InChIKey=SGTUOBURCVMACZ-SEVPPISGSA-N;   SMILES=[H][C@@]1(C\\C=C/CCCCC)O[C@@]1([H])\\C=C\\C(O)C\\C=C/CCCC(O)=O
 alt_id: CHEBI:34783;   CHEBI:5670
 xref: CAS:85589-24-8;   CAS:94161-11-2;   KEGG:C14808;   LIPID_MAPS_instance:LMFA03090005
 xref_mesh: MESH:C038243
 xref: PMID:10100848;   PMID:10644052;   PMID:15123652;   PMID:8573089;   Reaxys:21024403
 cyclic_relationship: is_conjugate_acid_of CHEBI:132127


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hepoxilin A3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases export ISO ABCC2 protein results in increased export of 8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid CTD PMID:30102254 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      biological role 19711
        biochemical role 19301
          metabolite 19282
            xenobiotic metabolite 14244
              human xenobiotic metabolite 13576
                hepoxilin A3 1
                  (8S)-hepoxilin A3 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        monocarboxylic acid 17523
                                          fatty acid 16011
                                            unsaturated fatty acid 949
                                              polyunsaturated fatty acid 685
                                                trienoic fatty acid 121
                                                  fatty acid 20:3 1
                                                    (5Z,9E,14Z)-icosa-5,9,14-trienoic acid 1
                                                      hepoxilin A3 1
                                                        (8S)-hepoxilin A3 0
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