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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hepoxilin A3
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Accession:CHEBI:36190 term browser browse the term
Definition:A hepoxilin having (5Z,9E,14Z) double bond stereochemistry, an 8-hydroxy substituent and an 11S,12S-epoxy group.
Synonyms:exact_synonym: (5Z,9E)-8-hydroxy-10-{(2S,3S)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl}deca-5,9-dienoic acid
 related_synonym: (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyeicosa-5,9,14-trienoic acid;   (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid;   8-EH-2;   8-Hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid;   8-hydroxy-10-(3-(2-octenyl)oxiranyl)-5,9-decadienoic acid;   8-hydroxy-11(S),12(S)-epoxy-eicosa- 5Z,9E,14Z-trienoic acid;   8-hydroxy-11S,12S-epoxy-5Z,14Z,9E-eicosatrienoic acid;   Formula=C20H32O4;   HXA3;   Hepoxilin A;   InChI=1S/C20H32O4/c1-2-3-4-5-6-10-13-18-19(24-18)16-15-17(21)12-9-7-8-11-14-20(22)23/h6-7,9-10,15-19,21H,2-5,8,11-14H2,1H3,(H,22,23)/b9-7-,10-6-,16-15+/t17?,18-,19-/m0/s1;   InChIKey=SGTUOBURCVMACZ-SEVPPISGSA-N;   SMILES=[H][C@@]1(C\\C=C/CCCCC)O[C@@]1([H])\\C=C\\C(O)C\\C=C/CCCC(O)=O
 alt_id: CHEBI:34783;   CHEBI:5670
 xref: CAS:85589-24-8;   CAS:94161-11-2;   KEGG:C14808;   LIPID_MAPS_instance:LMFA03090005
 xref_mesh: MESH:C038243
 xref: PMID:10100848;   PMID:10644052;   PMID:15123652;   PMID:8573089;   Reaxys:21024403
 cyclic_relationship: is_conjugate_acid_of CHEBI:132127


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hepoxilin A3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases export ISO ABCC2 protein results in increased export of 8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid CTD PMID:30102254 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      biological role 19902
        biochemical role 19598
          metabolite 19585
            xenobiotic metabolite 16172
              human xenobiotic metabolite 15789
                hepoxilin A3 1
                  (8S)-hepoxilin A3 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            heteroorganic entity 19559
                              organochalcogen compound 19317
                                organooxygen compound 19231
                                  carbon oxoacid 18687
                                    carboxylic acid 18684
                                      monocarboxylic acid 18025
                                        fatty acid 16852
                                          unsaturated fatty acid 1676
                                            polyunsaturated fatty acid 841
                                              trienoic fatty acid 268
                                                fatty acid 20:3 1
                                                  (5Z,9E,14Z)-icosa-5,9,14-trienoic acid 1
                                                    hepoxilin A3 1
                                                      (8S)-hepoxilin A3 0
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