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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alicyclic ketone
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Accession:CHEBI:36132 term browser browse the term
Definition:A cyclic ketone in which the carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system.
Synonyms:related_synonym: alicyclic ketones



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(+)-beta-thujone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO beta-thujone inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein]; beta-thujone inhibits the reaction [Choline results in increased activity of CHRNA7 protein] CTD PMID:28395994 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
(R)-camphor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a2 collagen type I alpha 2 chain affects expression ISO Camphor analog affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP Camphor results in decreased activity of CYP2B1 protein CTD PMID:9242356 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Camphor binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein] CTD PMID:21466812 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Camphor binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Runx2 RUNX family transcription factor 2 affects expression ISO Camphor analog affects the expression of RUNX2 mRNA CTD PMID:24704097 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sparc secreted protein acidic and cysteine rich affects expression ISO Camphor analog affects the expression of SPARC mRNA CTD PMID:24704097 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein] CTD PMID:18172555 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity
multiple interactions
ISO Camphor results in increased activity of TRPV3 protein
isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]
CTD PMID:21353389 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
13,14-dihydro-15-ketoprostaglandin D2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
ISO 13,14-dihydro-15-ketoprostaglandin D2 results in increased expression of CXCL2 protein
13,14-dihydro-15-ketoprostaglandin D2 promotes the reaction [Flutamide results in increased expression of CXCL2 mRNA]
CTD PMID:21094227 PMID:21735453 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO 13,14-dihydro-15-ketoprostaglandin D2 promotes the reaction [Flutamide results in increased expression of GATA3 mRNA] CTD PMID:21735453 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 13,14-dihydro-15-ketoprostaglandin D2 promotes the reaction [Flutamide results in increased expression of IL4 protein] CTD PMID:21735453 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO 13,14-dihydro-15-ketoprostaglandin D2 binds to and results in increased activity of PTGDR protein; 13,14-dihydro-15-ketoprostaglandin D2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO
EXP
13,14-dihydro-15-ketoprostaglandin D2 inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]
13,14-dihydro-15-ketoprostaglandin D2 binds to and results in increased activity of PTGDR2 protein
13,14-dihydro-15-ketoprostaglandin D2 binds to and results in increased activity of PTGDR2 protein; ramatroban inhibits the reaction [13,14-dihydro-15-ketoprostaglandin D2 binds to and results in increased activity of PTGDR2 protein]
CTD PMID:12721327 PMID:15528449 PMID:16256979 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213
JBrowse link
13,14-dihydro-Delta(12)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions
EXP 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]
CTD PMID:22982731 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA] CTD PMID:22982731 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
15-deoxy-Delta(12,14)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects export
affects glutathionylation
increases transport
ISO [ABCC1 protein results in increased transport of 15-deoxy-delta(12,14)-prostaglandin J2 metabolite] affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; [verlukast binds to and results in decreased activity of ABCC1 protein] inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]
ABCC1 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog
ABCC1 protein affects the glutathionylation of 15-deoxy-delta(12,14)-prostaglandin J2
CTD PMID:14979731 PMID:21728338 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects export ISO ABCC3 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog CTD PMID:14979731 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ACAA2 mRNA CTD PMID:34323617 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA CTD PMID:34323617 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Agt angiotensinogen multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in decreased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]] CTD PMID:18278065 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2 CTD PMID:19997560 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of AKT1 protein CTD PMID:16611854 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BGLAP mRNA CTD PMID:12021203 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC2 protein CTD PMID:15498850 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC3 protein CTD PMID:15498850 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of CASP3 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of CASP3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of CASP3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:11785780 PMID:15498850 PMID:16299251 PMID:23973622 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15498850 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:15498850 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]] CTD PMID:12847270 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Dexamethasone binds to NR3C1 protein] which results in decreased expression of CCL2 protein] CTD PMID:15187150 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA] CTD PMID:23688403 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CCN2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]] CTD PMID:19429239 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNA2 protein CTD PMID:15729575 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNB1 protein CTD PMID:15729575 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCND3 protein CTD PMID:15729575 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNE1 protein CTD PMID:15729575 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDK2 protein CTD PMID:15729575 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of CDKN1A
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDKN1A protein
CTD PMID:15254749 PMID:15729575 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CDKN1B protein CTD PMID:15729575 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of CEBPA mRNA CTD PMID:12021203 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CFLAR protein CTD PMID:15498850 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein]
CTD PMID:15498850 PMID:22245093 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CIDEC mRNA CTD PMID:34323617 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of COL1A1 mRNA CTD PMID:12021203 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]] CTD PMID:12604364 PMID:14998300 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of EGR1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Oxygen deficiency results in increased expression of EGR1 mRNA] CTD PMID:12468449 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Tretinoin] results in increased expression of FABP4 mRNA
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FABP4 mRNA
CTD PMID:9543393 PMID:12021203 PMID:16573735 PMID:34323617 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]; wortmannin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA]
CTD PMID:11457450 PMID:11687581 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]; [ABCC1 protein results in increased transport of 15-deoxy-delta(12,14)-prostaglandin J2 metabolite] affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; [verlukast binds to and results in decreased activity of ABCC1 protein] inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; NFE2L2 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein
CTD PMID:21728338 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
multiple interactions
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GFAP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of GFAP mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]
CTD PMID:15254749 PMID:15994020 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione] CTD PMID:14979731 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions
EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
CTD PMID:11600134 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC1 mRNA CTD PMID:21957481 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC2 mRNA CTD PMID:21957481 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HDAC3 mRNA CTD PMID:21957481 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects stability
multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 affects the stability of HIF1A protein
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Buthionine Sulfoximine promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]
CTD PMID:17658243 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein; [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]; HSF1 protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron]
ochratoxin A inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 protein
CTD PMID:11078701 PMID:15618017 PMID:15994020 PMID:19136476 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
increases activity
ISO HSF1 protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of HSF1 protein
CTD PMID:15618017 PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of HSPB1 protein CTD PMID:16299251 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
decreases secretion
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased secretion of IFNG protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased secretion of IFNG protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IFNG protein
CTD PMID:12847270 PMID:16844232 PMID:19888466 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:14998300 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
decreases activity
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein affects the localization of RELA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in decreased abundance of Prostaglandins]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [IL1B protein affects the localization of JUN protein]; Dexamethasone promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of CSF2 mRNA]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IL1B protein
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with IL1B protein] results in decreased secretion of IL1B protein
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of IL1B protein
CTD PMID:11457450 PMID:12604364 PMID:14998300 PMID:15751073 PMID:16461118 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of IL1RN mRNA CTD PMID:15751073 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; [Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2] CTD PMID:23688403 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:12604364 PMID:12847270 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ACAA2 mRNA; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CIDEC mRNA; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PLIN1 mRNA; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARA mRNA CTD PMID:34323617 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ins2 insulin 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified inhibits the reaction [INS protein results in increased secretion of Glucose]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of INS mRNA] CTD PMID:14625208 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA] CTD PMID:12847270 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]] CTD PMID:12847270 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [FOS protein binds to JUN protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [IL1B protein affects the localization of JUN protein] CTD PMID:11457450 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein] CTD PMID:16611854 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Lep leptin multiple interactions
increases secretion
ISO [Dexamethasone co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased secretion of LEP protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased secretion of LEP protein
CTD PMID:11092516 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:19922793 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lpl lipoprotein lipase increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of LPL mRNA CTD PMID:12021203 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of MAPK1 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MAPK1 protein; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK1 protein]
CTD PMID:11687581 PMID:12083801 PMID:16611854 PMID:19888466 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of MAPK3 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]; [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MAPK3 protein; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of MAPK3 protein]
CTD PMID:11687581 PMID:12083801 PMID:16611854 PMID:19888466 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO MED1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein] CTD PMID:16324150 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein; [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased expression of MMP1 mRNA; [[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; HMOX1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of MMP1 protein]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA] CTD PMID:19136476 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of MMP9 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of MMP9 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of MMP9 mRNA] CTD PMID:19997048 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of MTOR protein CTD PMID:16611854 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nes nestin increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NES protein CTD PMID:15212945 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 affects the localization of and results in increased activity of NFE2L2 protein; 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]; ABCC1 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [NFE2L2 protein results in increased expression of GCLC protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of NFE2L2 protein]; NFE2L2 protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and affects the localization of NFE2L2 protein; manganese chloride inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NFE2L2 protein]
CTD PMID:19136476 PMID:21728338 PMID:22245093 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases localization
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased localization of NFKB1 protein
CTD PMID:11457450 PMID:16299251 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased degradation of NFKBIA protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of NFKBIA protein
CTD PMID:15498850 PMID:22245093 PMID:23688403 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
decreases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of NOS2 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of NOS2 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of NOS2 mRNA]
CTD PMID:11457450 PMID:11890746 PMID:12847270 PMID:15684285 PMID:15994020 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 decreases activity EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of NOS3 protein CTD PMID:11890746 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects activity
multiple interactions
ISO 15-deoxy-delta(12,14)-prostaglandin J2 affects the activity of NR3C1 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Dexamethasone binds to NR3C1 protein] which results in decreased expression of CCL2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Dexamethasone binds to NR3C1 protein]
CTD PMID:15187150 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 protein] CTD PMID:22245093 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of PARP1 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein
CTD PMID:15498850 PMID:23973622 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PCK1 mRNA CTD PMID:9518257 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PLIN1 mRNA CTD PMID:34323617 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARA protein
[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARA mRNA
CTD PMID:9013583 PMID:34323617 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARD protein CTD PMID:17341418 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
decreases response to substance
increases expression
increases activity
multiple interactions
decreases expression
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 affects the expression of PPARG
PPARG protein mutant form results in decreased susceptibility to 15-deoxy-delta(12,14)-prostaglandin J2
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARG mRNA; 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARG protein
15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in decreased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in increased expression of PPARG mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [PPARG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]; MED1 protein promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]
15-deoxy-delta(12,14)-prostaglandin J2 affects the localization of and results in increased expression of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in decreased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased localization of and results in increased activity of PPARG protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARG mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARG mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; MG 262 promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; PPARG protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TBXA2R mRNA alternative form]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of PPARG protein
CTD PMID:9013583 PMID:10662598 PMID:11030710 PMID:12065695 PMID:12604364 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in increased expression of PTEN protein CTD PMID:16611854 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR protein; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein; ramatroban inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]
CTD PMID:12721327 PMID:16256979 NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO PTGS1 protein promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2] CTD PMID:17439952 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of PTGS2 protein; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of and results in decreased expression of PTGS2 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of PTGS2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PTGS2
CTD PMID:11457450 PMID:12604364 PMID:15254749 PMID:19997048 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 increases phosphorylation EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased phosphorylation of PTPN11 protein CTD PMID:12584205 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of and results in decreased phosphorylation of RAF1 protein CTD PMID:12083801 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ciglitazone promotes the reaction [SR 11237 results in increased expression of RARB protein]]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RARB
CTD PMID:12839938 PMID:15254749 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein affects the localization of RELA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased activity of RELA protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride affects the localization of RELA protein]
CTD PMID:11457450 PMID:15498850 PMID:20174873 PMID:22245093 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rig1 RNA sensor RIG-1 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of RIGI mRNA] CTD PMID:16303604 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of RPS6KA1 protein CTD PMID:16611854 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased expression of TGFB1 mRNA]; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of KLF6 protein] CTD PMID:16611854 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of RUNX2 mRNA CTD PMID:12021203 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RXRA CTD PMID:15254749 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]] CTD PMID:18278065 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]] CTD PMID:19429239 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of SOCS1 mRNA CTD PMID:12584205 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of SOCS3 mRNA CTD PMID:12584205 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of SPP1 mRNA CTD PMID:12021203 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of [STAT1 protein binds to STAT1 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [peroxyvanadate results in increased phosphorylation of STAT1 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; CAT protein inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; peroxyvanadate inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]
CTD PMID:12584205 PMID:12847270 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]; T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]
CTD PMID:12584205 PMID:12847270 PMID:19922793 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions
decreases expression
ISO PPARG protein affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TBXA2R mRNA alternative form] CTD PMID:16499875 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
G Tg thyroglobulin multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [TSHB protein results in increased expression of TG protein]
15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TG protein
CTD PMID:11078701 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
decreases response to substance
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CCN2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CCN2]]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TGFB1 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]
15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [alitretinoin results in decreased expression of TGFB1 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[alitretinoin co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased expression of TGFB1 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[alitretinoin co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in decreased expression of TGFB1 mRNA]; RPS6KB1 protein inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 co-treated with alitretinoin] results in decreased expression of TGFB1 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased susceptibility to TGFB1 protein
CTD PMID:16611854 PMID:18278065 PMID:19429239 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase increases expression EXP 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of TH protein CTD PMID:15212945 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
decreases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 mRNA]
15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TLR2 mRNA
CTD PMID:20174873 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of TNF protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:12604364 PMID:19888466 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 promotes the reaction [TSHB protein results in increased expression of TG protein] CTD PMID:11078701 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Vim vimentin decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of VIM CTD PMID:15254749 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wnt10b Wnt family member 10B decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of WNT10B mRNA CTD PMID:12021203 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of XIAP protein CTD PMID:15498850 PMID:16299251 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
16,16-dimethylprostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO 16,16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein
EGFR affects the reaction [16,16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein]
CTD PMID:15578100 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance
affects localization
ISO BAX results in increased susceptibility to 16,16-Dimethylprostaglandin E2
16,16-Dimethylprostaglandin E2 affects the localization of BAX protein
CTD PMID:15578100 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO EGFR affects the reaction [16,16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein] CTD PMID:15578100 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases activity ISO 16,16-Dimethylprostaglandin E2 results in increased activity of HPGD protein CTD PMID:14736730 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 PMID:11855677 PMID:11991626 PMID:18306037 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:11686837 PMID:11855677 PMID:11991626 PMID:15610444 PMID:18306037 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Flurbiprofen inhibits the reaction [16,16-Dimethylprostaglandin E2 results in increased expression of PTGS2 mRNA]
16,16-Dimethylprostaglandin E2 inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA]
CTD PMID:9099957 PMID:15610444 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 16,16-Dimethylprostaglandin E2 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF] CTD PMID:9298541 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
2-cyclopenten-1-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO cyclopentenone results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:18383863 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO cyclopentenone results in increased expression of CDKN1B CTD PMID:16061222 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO cyclopentenone results in decreased phosphorylation of RB1 protein CTD PMID:16061222 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
2-methoxyestrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions ISO [HSD17B2 protein results in increased metabolism of and results in decreased activity of 2-methoxyestradiol] which results in increased chemical synthesis of 2-methoxyestrone CTD PMID:16397246 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
28-deoxonimbolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO 28-deoxonimbolide results in increased activity of CASP3 protein CTD PMID:21381696 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO 28-deoxonimbolide results in increased activity of CASP8 protein CTD PMID:21381696 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO 28-deoxonimbolide results in increased activity of CASP9 protein CTD PMID:21381696 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
AH23848 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to AKT1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of AKT1 protein CTD PMID:19407222 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to IL1R1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to TNFRSF1A protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [ARRB1 protein modified form binds to SRC protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of ARRB1 protein CTD PMID:19407222 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Axin1 axin 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [AXIN1 protein binds to CTNNB1 protein] CTD PMID:19407222 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2L1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of BAD protein CTD PMID:19407222 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAX protein binds to BCL2 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAX protein binds to BCL2L1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased expression of BAX protein CTD PMID:19407222 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAX protein binds to BCL2 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of BCL2 protein CTD PMID:19407222 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAD protein binds to BCL2L1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [BAX protein binds to BCL2L1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of BCL2L1 protein CTD PMID:19407222 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased cleavage of and results in increased activity of CASP3 protein
AH 23848 inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP3 protein]
CTD PMID:19407222 PMID:32115946 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [AXIN1 protein binds to CTNNB1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [GSK3B protein binds to CTNNB1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased degradation of CTNNB1 protein CTD PMID:19407222 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO AH 23848 inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]; AH 23848 inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]; AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]; AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein] CTD PMID:20678559 PMID:28571770 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO AH 23848 inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]; AH 23848 inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein] CTD PMID:20093341 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of and results in decreased expression of EGFR protein CTD PMID:19407222 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of EGR1 protein CTD PMID:19407222 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of FOS protein CTD PMID:19407222 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to AKT1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to MAPK1 protein binds to MAPK3 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [GSK3B protein binds to CTNNB1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of GSK3B protein CTD PMID:19407222 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to IL1R1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of IL1R1 protein CTD PMID:19407222 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of JUN protein CTD PMID:19407222 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lep leptin multiple interactions ISO AH 23848 inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]; AH 23848 inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein] CTD PMID:28571770 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to MAPK1 protein binds to MAPK3 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of MAPK1 protein CTD PMID:19407222 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to MAPK1 protein binds to MAPK3 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of MAPK3 protein CTD PMID:19407222 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO AH 23848 inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein] CTD PMID:30269738 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of MYC protein CTD PMID:19407222 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of NFKB1 protein CTD PMID:19407222 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of NFKBIA protein CTD PMID:19407222 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:19407222 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER2 protein binds to SRC protein] CTD PMID:19407222 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER4 protein binds to SRC protein]; AH 23848 binds to and results in decreased activity of PTGER4 protein CTD PMID:19407222 PMID:30269738 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of PTGS2 mRNA]; AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of PTGS2 protein] CTD PMID:20678559 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of and results in decreased expression of RELA protein CTD PMID:19407222 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of SP1 protein CTD PMID:19407222 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to IL1R1 protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to TNFRSF1A protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [ARRB1 protein modified form binds to SRC protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER2 protein binds to SRC protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER4 protein binds to SRC protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of SRC protein CTD PMID:19407222 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tcf7 transcription factor 7 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of TCF7 protein CTD PMID:19407222 NCBI chr10:36,423,443...36,454,350
Ensembl chr10:36,423,445...36,453,535
JBrowse link
G Tcf7l2 transcription factor 7 like 2 multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of TCF7L2 protein CTD PMID:19407222 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO AH 23848 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF] CTD PMID:9298541 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to TNFRSF1A protein]; [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of TNFRSF1A protein CTD PMID:19407222 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
Ankaflavin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression ISO ankaflavin results in increased expression of NR1H4 mRNA CTD PMID:24275089 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
multiple interactions
ISO ankaflavin results in increased expression of PPARA mRNA
ankaflavin affects the reaction [PPARA protein affects the oxidation of Fatty Acids]; ankaflavin binds to and results in increased activity of PPARA protein
CTD PMID:24275089 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO ankaflavin results in increased expression of PPARGC1A mRNA CTD PMID:24275089 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
azadiradione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO azadiradione results in increased activity of CASP3 protein CTD PMID:21381696 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO azadiradione results in increased activity of CASP8 protein CTD PMID:21381696 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO azadiradione results in increased activity of CASP9 protein CTD PMID:21381696 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO azadiradione results in increased expression of HSPA1A mRNA CTD PMID:30309986 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
Bardoxolone methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B decreases activity ISO bardoxolone methyl results in decreased activity of ADRA1B protein CTD PMID:28790194 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adra2c adrenoceptor alpha 2C decreases activity ISO bardoxolone methyl results in decreased activity of ADRA2C protein CTD PMID:28790194 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of AKT1 protein] CTD PMID:27417254 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Anxa1 annexin A1 affects expression ISO bardoxolone methyl affects the expression of ANXA1 mRNA CTD PMID:34480604 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Arg1 arginase 1 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of ARG1 mRNA] CTD PMID:26918785 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Aurkb aurora kinase B decreases activity ISO bardoxolone methyl results in decreased activity of AURKB protein CTD PMID:28790194 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases activity ISO bardoxolone methyl results in decreased activity of AVPR1A protein CTD PMID:28790194 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO bardoxolone methyl results in increased expression of B4GALT1 mRNA CTD PMID:35724838 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO bardoxolone methyl results in increased expression of BBC3 mRNA CTD PMID:35724838 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased expression of BDNF protein] CTD PMID:27417254 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO bardoxolone methyl results in increased expression of BIRC3 mRNA CTD PMID:35724838 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C decreases activity ISO bardoxolone methyl results in decreased activity of CACNA1C protein CTD PMID:28790194 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Casp8 caspase 8 decreases expression ISO bardoxolone methyl results in decreased expression of CASP8 protein CTD PMID:25246272 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CCL11 protein] CTD PMID:26918785 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CCL2 protein]
bardoxolone methyl results in increased expression of CCL2 mRNA
CTD PMID:26918785 PMID:35724838 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO bardoxolone methyl results in increased expression of CCL20 mRNA CTD PMID:35724838 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CCL3 protein] CTD PMID:26918785 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CCL4 protein] CTD PMID:26918785 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CCL5 protein] CTD PMID:26918785 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions ISO bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of CCR5 mRNA] CTD PMID:26918785 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd163 CD163 molecule multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of CD163 mRNA]; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of CD163 protein] CTD PMID:26918785 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases activity ISO bardoxolone methyl results in decreased activity of CHRM1 protein CTD PMID:28790194 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases activity ISO bardoxolone methyl results in decreased activity of CHRM2 protein CTD PMID:28790194 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Clec10a C-type lectin domain containing 10A multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of CLEC10A mRNA] CTD PMID:26918785 NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO bardoxolone methyl results in increased expression of CXCL1 mRNA CTD PMID:35724838 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CXCL2 protein]
bardoxolone methyl results in increased expression of CXCL2 mRNA
CTD PMID:26918785 PMID:35724838 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO bardoxolone methyl results in increased expression of CXCL1 mRNA CTD PMID:35724838 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO bardoxolone methyl results in increased expression of DDIT3 protein
ochratoxin A promotes the reaction [bardoxolone methyl results in increased expression of DDIT3 protein]; Ursolic Acid inhibits the reaction [ochratoxin A promotes the reaction [bardoxolone methyl results in increased expression of DDIT3 protein]]
CTD PMID:35724838 PMID:36587836 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 affects expression ISO bardoxolone methyl affects the expression of DNAJB1 mRNA CTD PMID:34480604 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Drd1 dopamine receptor D1 decreases activity ISO bardoxolone methyl results in decreased activity of DRD1 protein CTD PMID:28790194 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 decreases activity ISO bardoxolone methyl results in decreased activity of DRD2 protein CTD PMID:28790194 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Edn1 endothelin 1 increases expression ISO bardoxolone methyl results in increased expression of EDN1 mRNA CTD PMID:35724838 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression ISO bardoxolone methyl affects the expression of EGLN3 mRNA CTD PMID:34480604 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO bardoxolone methyl results in decreased expression of and results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:35929395 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Fasn fatty acid synthase decreases expression ISO bardoxolone methyl results in decreased expression of FASN mRNA CTD PMID:20372807 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO bardoxolone methyl results in increased expression of FMO2 mRNA CTD PMID:25056779 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of and results in decreased phosphorylation of FOXO1 protein] CTD PMID:27417254 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO bardoxolone methyl affects the expression of GADD45A mRNA CTD PMID:34480604 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
decreases expression
ISO bardoxolone methyl results in increased expression of GCLC mRNA; bardoxolone methyl results in increased expression of GCLC protein
bardoxolone methyl results in decreased expression of GCLC mRNA
CTD PMID:27480280 PMID:34480604 PMID:35724838 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
decreases expression
ISO bardoxolone methyl results in increased expression of GCLM; bardoxolone methyl results in increased expression of GCLM mRNA
bardoxolone methyl results in decreased expression of GCLM mRNA
CTD PMID:21723306 PMID:34480604 PMID:35724838 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression ISO bardoxolone methyl affects the expression of GPX2 mRNA CTD PMID:34480604 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
ISO GSK3B protein mutant form inhibits the reaction [bardoxolone methyl results in increased expression of HMOX1 protein]; GSK3B protein mutant form inhibits the reaction [bardoxolone methyl results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression ISO bardoxolone methyl results in decreased expression of GSTA1 mRNA CTD PMID:34480604 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO bardoxolone methyl results in increased expression of GSTP1 mRNA CTD PMID:34480604 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression
ISO bardoxolone methyl inhibits the reaction [eriodictyol results in decreased expression of HMOX1 protein]; GSK3B protein mutant form inhibits the reaction [bardoxolone methyl results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [bardoxolone methyl results in increased expression of HMOX1 protein]
bardoxolone methyl results in decreased expression of HMOX1 mRNA
bardoxolone methyl results in increased expression of HMOX1 mRNA; bardoxolone methyl results in increased expression of HMOX1 protein
[bardoxolone methyl co-treated with aristolochic acid I] results in increased expression of HMOX1 mRNA; bardoxolone methyl promotes the reaction [aristolochic acid I results in increased expression of HMOX1 protein]
CTD PMID:21289052 PMID:24530882 PMID:25246272 PMID:28790194 PMID:34480604 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrh1 histamine receptor H 1 decreases activity ISO bardoxolone methyl results in decreased activity of HRH1 protein CTD PMID:28790194 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO bardoxolone methyl results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO bardoxolone methyl results in increased expression of HSPA5 protein
ochratoxin A promotes the reaction [bardoxolone methyl results in increased expression of HSPA5 protein]
CTD PMID:35724838 PMID:36587836 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A decreases activity ISO bardoxolone methyl results in decreased activity of HTR2A protein CTD PMID:28790194 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C decreases activity ISO bardoxolone methyl results in decreased activity of HTR2C protein CTD PMID:28790194 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO bardoxolone methyl inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; bardoxolone methyl inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:35724838 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO bardoxolone methyl inhibits the reaction [IFNG protein results in increased expression of NOS2] CTD PMID:17363558 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL10 protein]; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA] CTD PMID:26918785 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL17A protein] CTD PMID:26918785 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO bardoxolone methyl inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; bardoxolone methyl inhibits the reaction [IL1B protein affects the localization of RELA protein]; bardoxolone methyl inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; bardoxolone methyl inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein] CTD PMID:35724838 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 affects expression ISO bardoxolone methyl affects the expression of IL1R1 mRNA CTD PMID:34480604 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il6 interleukin 6 multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein] CTD PMID:26918785 PMID:27417254 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO bardoxolone methyl inhibits the reaction [INS protein results in increased phosphorylation of RPS6 protein] CTD PMID:28790194 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Irf5 interferon regulatory factor 5 multiple interactions ISO bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of IRF5 mRNA] CTD PMID:26918785 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of JAK2 protein] CTD PMID:27417254 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression
decreases expression
multiple interactions
ISO bardoxolone methyl results in increased expression of KEAP1 protein
bardoxolone methyl results in decreased expression of KEAP1 mRNA
bardoxolone methyl inhibits the reaction [aristolochic acid I results in increased expression of KEAP1 protein]
CTD PMID:24530882 PMID:27358234 PMID:35724838 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Lep leptin multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased susceptibility to LEP protein]; bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of LEP protein] CTD PMID:27417254 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of LIF protein] CTD PMID:26918785 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial decreases expression ISO bardoxolone methyl results in decreased expression of LONP1 protein CTD PMID:36587836 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Mafg MAF bZIP transcription factor G affects expression
decreases expression
ISO bardoxolone methyl affects the expression of MAFG mRNA
bardoxolone methyl results in decreased expression of MAFG mRNA
CTD PMID:34480604 PMID:35724838 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO bardoxolone methyl results in decreased expression of MFN1 protein CTD PMID:35929395 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO bardoxolone methyl results in decreased expression of MFN2 protein CTD PMID:35929395 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of MRC1 protein] CTD PMID:26918785 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO bardoxolone methyl results in decreased phosphorylation of MTOR protein CTD PMID:35929395 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
increases localization
decreases response to substance
increases activity
ISO
EXP
bardoxolone methyl results in increased expression of NFE2L2 mRNA; bardoxolone methyl results in increased expression of NFE2L2 protein
bardoxolone methyl inhibits the reaction [aristolochic acid I results in decreased expression of and affects the localization of NFE2L2 protein]; bardoxolone methyl inhibits the reaction [aristolochic acid I results in decreased expression of NFE2L2 mRNA]
bardoxolone methyl results in increased localization of NFE2L2 protein
NFE2L2 gene mutant form results in decreased susceptibility to bardoxolone methyl
bardoxolone methyl inhibits the reaction [eriodictyol results in decreased phosphorylation of NFE2L2 protein]; bardoxolone methyl results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 promotes the reaction [bardoxolone methyl results in increased expression of SRXN1 protein]; NFE2L2 protein affects the reaction [bardoxolone methyl results in increased expression of HMOX1 protein]
bardoxolone methyl results in increased activity of NFE2L2 protein
CTD PMID:21289052 PMID:21723306 PMID:24530882 PMID:24798383 PMID:25246272 More... NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased expression of NFKBIA protein]
bardoxolone methyl inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; bardoxolone methyl inhibits the reaction [TNF protein affects the localization of NFKBIA protein]
CTD PMID:25637688 PMID:35724838 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO bardoxolone methyl results in increased expression of NFKBIE mRNA CTD PMID:35724838 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO bardoxolone methyl inhibits the reaction [IFNG protein results in increased expression of NOS2] CTD PMID:17363558 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
decreases expression
increases activity
ISO bardoxolone methyl results in increased expression of NQO1 mRNA; bardoxolone methyl results in increased expression of NQO1 protein
bardoxolone methyl inhibits the reaction [eriodictyol results in decreased expression of NQO1 protein]
bardoxolone methyl results in decreased expression of NQO1 mRNA
bardoxolone methyl results in increased activity of NQO1 protein
[bardoxolone methyl co-treated with aristolochic acid I] results in increased expression of NQO1 mRNA; [bardoxolone methyl co-treated with aristolochic acid I] results in increased expression of NQO1 protein
CTD PMID:24530882 PMID:27480280 PMID:28790194 PMID:34480604 PMID:35724838 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO bardoxolone methyl results in increased expression of OLR1 mRNA CTD PMID:35724838 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases cleavage ISO bardoxolone methyl results in increased cleavage of OPA1 protein CTD PMID:35929395 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Oprk1 opioid receptor, kappa 1 decreases activity ISO bardoxolone methyl results in decreased activity of OPRK1 protein CTD PMID:28790194 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 decreases activity ISO bardoxolone methyl results in decreased activity of OPRM1 protein CTD PMID:28790194 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO bardoxolone methyl results in increased cleavage of PARP1 protein CTD PMID:17363558 PMID:25246272 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pde4b phosphodiesterase 4B decreases activity ISO bardoxolone methyl results in decreased activity of PDE4B protein CTD PMID:28790194 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression ISO bardoxolone methyl results in increased expression of PDGFB mRNA CTD PMID:35724838 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO bardoxolone methyl results in decreased expression of PFKM protein CTD PMID:35929395 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pkm pyruvate kinase M1/2 decreases expression ISO bardoxolone methyl results in decreased expression of PKM protein CTD PMID:35929395 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO bardoxolone methyl results in increased expression of PLAU mRNA CTD PMID:35724838 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO bardoxolone methyl results in increased expression of PPARG mRNA; bardoxolone methyl results in increased expression of PPARG protein CTD PMID:21289052 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 affects expression ISO bardoxolone methyl affects the expression of PRKAG2 mRNA CTD PMID:35724838 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of PTPN1 protein] CTD PMID:27417254 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Rara retinoic acid receptor, alpha affects expression ISO bardoxolone methyl affects the expression of RARA mRNA CTD PMID:34480604 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO bardoxolone methyl inhibits the reaction [IL1B protein affects the localization of RELA protein]; bardoxolone methyl inhibits the reaction [TNF protein affects the localization of RELA protein] CTD PMID:35724838 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
decreases expression
ISO bardoxolone methyl inhibits the reaction [INS protein results in increased phosphorylation of RPS6 protein]
bardoxolone methyl results in decreased expression of RPS6 protein
CTD PMID:28790194 PMID:35929395 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO bardoxolone methyl results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35929395 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Scarb1 scavenger receptor class B, member 1 affects expression ISO bardoxolone methyl affects the expression of SCARB1 mRNA CTD PMID:34480604 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 affects expression ISO bardoxolone methyl affects the expression of SH3BP5 mRNA CTD PMID:34480604 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 multiple interactions
decreases expression
ISO Ursolic Acid inhibits the reaction [bardoxolone methyl results in decreased expression of SIGMAR1 protein] CTD PMID:36587836 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression
decreases glycosylation
ISO bardoxolone methyl results in decreased expression of SLC1A5 protein
bardoxolone methyl results in decreased glycosylation of SLC1A5 protein
CTD PMID:35929395 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc3a2 solute carrier family 3 member 2 decreases expression ISO bardoxolone methyl results in decreased expression of SLC3A2 mRNA CTD PMID:35724838 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc47a1 solute carrier family 47 member 1 increases expression ISO bardoxolone methyl results in increased expression of SLC47A1 mRNA; bardoxolone methyl results in increased expression of SLC47A1 protein CTD PMID:27480280 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA] CTD PMID:26918785 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sqstm1 sequestosome 1 affects expression
decreases expression
ISO bardoxolone methyl affects the expression of SQSTM1 mRNA
bardoxolone methyl results in decreased expression of SQSTM1 mRNA
CTD PMID:34480604 PMID:35724838 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression
decreases expression
multiple interactions
ISO bardoxolone methyl results in increased expression of SRXN1 protein
bardoxolone methyl results in decreased expression of SRXN1 mRNA
bardoxolone methyl results in increased expression of SRXN1 mRNA; bardoxolone methyl results in increased expression of SRXN1 protein
NFE2L2 promotes the reaction [bardoxolone methyl results in increased expression of SRXN1 protein]
CTD PMID:27358234 PMID:34480604 PMID:35724838 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation
ISO [bardoxolone methyl co-treated with Dietary Fats] results in decreased expression of STAT3 protein; bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of STAT3 protein]
bardoxolone methyl results in decreased phosphorylation of STAT3 protein
CTD PMID:17363558 PMID:25637688 PMID:27417254 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tacr1 tachykinin receptor 1 decreases activity ISO bardoxolone methyl results in decreased activity of TACR1 protein CTD PMID:28790194 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO bardoxolone methyl results in increased expression of TAP1 mRNA CTD PMID:35724838 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of TH protein] CTD PMID:25637688 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO bardoxolone methyl results in decreased expression of THRSP mRNA CTD PMID:20372807 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO bardoxolone methyl inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; bardoxolone methyl inhibits the reaction [TNF protein affects the localization of RELA protein]; bardoxolone methyl inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; bardoxolone methyl inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
[bardoxolone methyl co-treated with Dietary Fats] results in decreased expression of TNF protein; bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of TNF protein]; bardoxolone methyl inhibits the reaction [Dietary Fats results in increased expression of TNF]; bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; bardoxolone methyl promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:25637688 PMID:26612656 PMID:26918785 PMID:27417254 PMID:35724838 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression
multiple interactions
ISO bardoxolone methyl results in increased expression of TNFAIP3 mRNA; bardoxolone methyl results in increased expression of TNFAIP3 protein
bardoxolone methyl inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; bardoxolone methyl inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]
CTD PMID:35724838 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO bardoxolone methyl results in increased expression of TNFRSF9 mRNA CTD PMID:35724838 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO bardoxolone methyl results in decreased expression of TRIB3 mRNA CTD PMID:35724838 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
decreases expression
ISO bardoxolone methyl results in increased expression of TXNRD1 mRNA
bardoxolone methyl results in decreased expression of TXNRD1 mRNA
CTD PMID:34480604 PMID:35724838 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased expression of UCP2 protein] CTD PMID:25637688 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO bardoxolone methyl results in increased expression of VCAM1 mRNA CTD PMID:35724838 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
ISO bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of VEGFA protein]; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]
bardoxolone methyl results in decreased expression of VEGFA mRNA
CTD PMID:26918785 PMID:35724838 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A affects expression
decreases expression
ISO bardoxolone methyl affects the expression of ZFAND2A mRNA
bardoxolone methyl results in decreased expression of ZFAND2A mRNA
CTD PMID:34480604 PMID:35724838 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
JBrowse link
beta-damascenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calml5 calmodulin-like 5 increases expression ISO beta-damascenone results in increased expression of CALM4 mRNA CTD PMID:22982537 NCBI chr17:66,394,433...66,395,352 JBrowse link
G Casp14 caspase 14 increases expression
affects localization
ISO beta-damascenone results in increased expression of CASP14 mRNA
beta-damascenone affects the localization of CASP14 protein
CTD PMID:22982537 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Ces3a carboxylesterase 3a increases expression ISO beta-damascenone results in increased expression of CES3 mRNA CTD PMID:22982537 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO beta-damascenone results in increased expression of CLCA1 mRNA CTD PMID:22982537 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Clca2 chloride channel accessory 2 increases expression ISO beta-damascenone results in increased expression of CLCA2 mRNA CTD PMID:22982537 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO beta-damascenone results in increased expression of CYP17A1 mRNA CTD PMID:22982537 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Fcgbp Fc gamma binding protein increases expression ISO beta-damascenone results in increased expression of FCGBP mRNA CTD PMID:22982537 NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083
JBrowse link
G Flg filaggrin increases expression ISO beta-damascenone results in increased expression of FLG mRNA; beta-damascenone results in increased expression of FLG protein CTD PMID:22982537 NCBI chr 2:178,884,793...178,912,986 JBrowse link
G Hrnr hornerin increases expression ISO beta-damascenone results in increased expression of HRNR mRNA CTD PMID:22982537
G Il20ra interleukin 20 receptor subunit alpha increases expression ISO beta-damascenone results in increased expression of IL20RA mRNA CTD PMID:22982537 NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO beta-damascenone results in increased expression of IL36RN mRNA CTD PMID:22982537 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Krt1 keratin 1 increases expression ISO beta-damascenone results in increased expression of KRT1 mRNA CTD PMID:22982537 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt10 keratin 10 increases expression ISO beta-damascenone results in increased expression of KRT10 mRNA CTD PMID:22982537 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Lce1b late cornified envelope 1B increases expression ISO beta-damascenone results in increased expression of LCE1B mRNA CTD PMID:22982537 NCBI chr 2:178,255,351...178,257,533
Ensembl chr 2:178,256,213...178,257,985
JBrowse link
G Lce1d late cornified envelope 1D increases expression ISO beta-damascenone results in increased expression of LCE1D mRNA CTD PMID:22982537
G Lce1f late cornified envelope 1F increases expression ISO beta-damascenone results in increased expression of LCE1F mRNA CTD PMID:22982537 NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372
JBrowse link
G Lipm lipase, family member M increases expression ISO beta-damascenone results in increased expression of LIPM mRNA CTD PMID:22982537 NCBI chr 1:231,618,145...231,637,599
Ensembl chr 1:231,618,284...231,637,410
JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression ISO beta-damascenone results in increased expression of LORICRIN mRNA CTD PMID:22982537 NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807
JBrowse link
G Otop3 otopetrin 3 increases expression ISO beta-damascenone results in increased expression of OTOP3 mRNA CTD PMID:22982537 NCBI chr10:100,577,346...100,588,729
Ensembl chr10:100,577,392...100,588,726
JBrowse link
G Pla2g4f phospholipase A2, group IVF increases expression ISO beta-damascenone results in increased expression of PLA2G4F mRNA CTD PMID:22982537 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689
JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 increases expression ISO beta-damascenone results in increased expression of PLCXD1 mRNA CTD PMID:22982537 NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 increases expression ISO beta-damascenone results in increased expression of SDR16C5 mRNA CTD PMID:22982537 NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970
JBrowse link
G Susd2 sushi domain containing 2 increases expression ISO beta-damascenone results in increased expression of SUSD2 mRNA CTD PMID:22982537 NCBI chr20:13,017,516...13,024,820
Ensembl chr20:13,017,477...13,024,903
JBrowse link
G Tmprss4 transmembrane serine protease 4 increases expression ISO beta-damascenone results in increased expression of TMPRSS4 mRNA CTD PMID:22982537 NCBI chr 8:45,475,819...45,508,409
Ensembl chr 8:45,476,053...45,508,409
JBrowse link
camphor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a2 collagen type I alpha 2 chain affects expression ISO Camphor analog affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP Camphor results in decreased activity of CYP2B1 protein CTD PMID:9242356 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Camphor inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] CTD PMID:18611395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Camphor binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15588619 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Camphor inhibits the reaction [cinnamaldehyde results in increased activity of MPO protein] CTD PMID:21466812 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Camphor binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Runx2 RUNX family transcription factor 2 affects expression ISO Camphor analog affects the expression of RUNX2 mRNA CTD PMID:24704097 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sparc secreted protein acidic and cysteine rich affects expression ISO Camphor analog affects the expression of SPARC mRNA CTD PMID:24704097 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein] CTD PMID:18172555 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity
multiple interactions
ISO Camphor results in increased activity of TRPV3 protein
isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein]
CTD PMID:21353389 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
cyclohexanone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO
EXP
cyclohexanone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein] CTD PMID:2554539 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Pgr progesterone receptor multiple interactions ISO cyclohexanone binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
cyclohexanones term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Or5d18 olfactory receptor family 5 subfamily D member 18 multiple interactions ISO Cyclohexanones binds to and results in increased activity of OR5D18 protein CTD PMID:21142015 NCBI chr 3:73,516,522...73,517,463
Ensembl chr 3:73,516,364...73,519,858
Ensembl chr 3:73,516,364...73,519,858
JBrowse link
cyclopentanone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 increases reduction
multiple interactions
ISO AKR1C1 protein results in increased reduction of cyclopentanone
NADP promotes the reaction [AKR1C1 protein results in increased reduction of cyclopentanone]
CTD PMID:23261716 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 multiple interactions
increases reduction
ISO [AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone; NADP promotes the reaction [AKR1C2 protein results in increased reduction of cyclopentanone]; Ursodeoxycholic Acid inhibits the reaction [[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone] CTD PMID:23261716 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions
increases reduction
ISO [AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone; Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone]; NADP promotes the reaction [AKR1C3 protein results in increased reduction of cyclopentanone] CTD PMID:23261716 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
diphenylcyclopropenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression ISO diphenylcyclopropenone results in increased expression of ADM mRNA CTD PMID:25236440 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ankrd37 ankyrin repeat domain 37 increases expression ISO diphenylcyclopropenone results in increased expression of ANKRD37 mRNA CTD PMID:25236440 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
JBrowse link
G Cdk12 cyclin-dependent kinase 12 decreases expression ISO diphenylcyclopropenone results in decreased expression of CDK12 mRNA CTD PMID:25236440 NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
Ensembl chr10:83,201,211...83,280,888
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO diphenylcyclopropenone results in decreased expression of DNMT3B mRNA CTD PMID:25236440 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO diphenylcyclopropenone results in increased expression of FOS mRNA CTD PMID:25236440 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO diphenylcyclopropenone results in increased expression of FOSL1 mRNA CTD PMID:25236440 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO diphenylcyclopropenone results in increased expression of HMOX1 mRNA CTD PMID:20491607 PMID:25236440 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO diphenylcyclopropenone results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mt1 metallothionein 1 increases expression ISO diphenylcyclopropenone results in increased expression of MT1A mRNA CTD PMID:20491607 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A increases expression ISO diphenylcyclopropenone results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Rbm5 RNA binding motif protein 5 decreases expression ISO diphenylcyclopropenone results in decreased expression of RBM5 mRNA CTD PMID:25236440 NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO diphenylcyclopropenone results in increased expression of SRXN1 mRNA CTD PMID:25236440 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO diphenylcyclopropenone results in decreased expression of STC2 mRNA CTD PMID:25236440 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO diphenylcyclopropenone results in increased expression of TXN mRNA CTD PMID:20491607 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
fenchone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO fenchone binds to and results in decreased activity of NR3C1 protein CTD PMID:27633901 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO fenchone binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
glycyrrhetinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA] CTD PMID:28549656 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which affects the susceptibility to Vinblastine; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which results in increased abundance of Daunorubicin; Glycyrrhetinic Acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]; Glycyrrhetinic Acid inhibits the reaction [Verapamil results in increased activity of ABCB1 protein] CTD PMID:16904803 PMID:18204840 PMID:24380838 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA] CTD PMID:28549656 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases activity
ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC1 mRNA]
Glycyrrhetinic Acid results in increased activity of ABCC1 protein
[Glycyrrhetinic Acid affects the activity of ABCC1 protein] which affects the susceptibility to Doxorubicin; [Glycyrrhetinic Acid affects the activity of ABCC1 protein] which results in increased abundance of fluorexon
CTD PMID:18204840 PMID:28549656 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP Glycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide] CTD PMID:18436619 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO 18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA] CTD PMID:28549656 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide] CTD PMID:18436619 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCG5 mRNA] CTD PMID:28549656 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO 18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ACAT2 mRNA] CTD PMID:28549656 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [Monocrotaline results in increased expression of ACTA2 protein] CTD PMID:31325423 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Glycyrrhetinic Acid results in decreased activity of AKR1C1 protein CTD PMID:12604236 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Glycyrrhetinic Acid results in decreased activity of AKR1C2 protein CTD PMID:12604236 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 affects activity
decreases activity
ISO 18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein
Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein
CTD PMID:11165023 PMID:12604236 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of Glycyrrhetinic Acid CTD PMID:8831264 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of ALPL mRNA] CTD PMID:21910061 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ATF6 mRNA] CTD PMID:35699857 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ATP8B1 mRNA] CTD PMID:28549656 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of BAX]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased expression of BAX protein]
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of BAX protein]
CTD PMID:28414158 PMID:31325423 PMID:35699857 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in decreased expression of BCL2]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of BCL2 protein]
CTD PMID:28414158 PMID:31325423 PMID:35699857 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of BGLAP protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of BGLAP mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of BGLAP mRNA] CTD PMID:21910061 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of BGLAP protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of BGLAP mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA] CTD PMID:21910061 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Casp3 caspase 3 multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of CASP3] CTD PMID:35699857 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT mRNA] CTD PMID:23341968 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of CDKN1B protein] CTD PMID:31325423 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA] CTD PMID:21910061 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Glycyrrhetinic Acid promotes the reaction [Hydrocortisone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] CTD PMID:10460758 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein CTD PMID:21800547 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein CTD PMID:21800547 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] CTD PMID:28549656 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of EIF2AK3 mRNA] CTD PMID:35699857 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO
EXP
18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein]
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ERN1 mRNA]
CTD PMID:29444456 PMID:35699857 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased activity of GGT1 protein] CTD PMID:28414158 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased activity of GPT protein]
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of GPT protein]; Glycyrrhetinic Acid inhibits the reaction [diosbulbin B results in increased activity of GPT protein]
CTD PMID:28414158 PMID:28549656 PMID:36807597 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPX2 mRNA] CTD PMID:23341968 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of HMOX1 mRNA] CTD PMID:28414158 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression ISO Glycyrrhetinic Acid results in decreased expression of HRAS protein CTD PMID:19958823 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases activity ISO 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity
multiple interactions
ISO 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B2 protein
Glycyrrhetinic Acid inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein]; Glycyrrhetinic Acid inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein]
CTD PMID:24135201 PMID:31927052 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Glycyrrhetinic Acid co-treated with NADP] binds to HSD3B1 protein CTD PMID:25526675 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of HSPA5 mRNA] CTD PMID:35699857 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Glycyrrhetinic Acid promotes the reaction [Hydrocortisone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]]
Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased expression of IL1B protein]
CTD PMID:10460758 PMID:23373965 PMID:28414158 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA] CTD PMID:21644799 PMID:23373965 PMID:24849676 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]] CTD PMID:28213090 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions
increases expression
ISO [Glycyrrhetinic Acid co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IRAK3 mRNA; IRAK3 protein promotes the reaction [Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]
Glycyrrhetinic Acid results in increased expression of IRAK3 protein
CTD PMID:28213090 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Ly96 lymphocyte antigen 96 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]] CTD PMID:28213090 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of MAP3K5 protein] CTD PMID:29444456 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein] CTD PMID:23373965 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein] CTD PMID:23373965 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA] CTD PMID:24613819 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [diosbulbin B results in increased activity of MPO protein] CTD PMID:36807597 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MTTP mRNA] CTD PMID:28549656 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
ISO
EXP
[Glycyrrhetinic Acid results in increased expression of NFE2L2] which results in decreased susceptibility to Carbon Tetrachloride; Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride affects the localization of NFE2L2 protein]
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 protein]
CTD PMID:23341968 PMID:28414158 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of NFKB1 protein] CTD PMID:24613819 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased phosphorylation of NFKBIA protein]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of NFKBIA protein]
CTD PMID:23373965 PMID:24613819 PMID:28213090 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:21644799 PMID:23373965 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of NPC1L1 mRNA] CTD PMID:28549656 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP glycyrrhetinic acid inhibits the reaction [1-naphthyl isothiocyanate decreases expression of Nr1h4 mRNA in liver] RGD PMID:30061734 RGD:15092071 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of BAX protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in decreased expression of CDKN1B protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of BCL2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of RHOA mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of RHOA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK1 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK1 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased phosphorylation of PPP1R12A protein] CTD PMID:31325423 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta decreases activity ISO 18alpha-glycyrrhetinic acid results in decreased activity of PIK3CD protein CTD PMID:21644799 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma decreases activity ISO 18alpha-glycyrrhetinic acid results in decreased activity of PIK3CG protein CTD PMID:21644799 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of PPARG mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of PPARG protein] CTD PMID:28414158 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased phosphorylation of PPP1R12A protein] CTD PMID:31325423 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] CTD PMID:21644799 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of RELA protein]
Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]
CTD PMID:23373965 PMID:24613819 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin decreases activity ISO Glycyrrhetinic Acid results in decreased activity of REN protein CTD PMID:20460744 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of RHOA mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of RHOA protein] CTD PMID:31325423 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK1 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK1 protein] CTD PMID:31325423 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 protein] CTD PMID:31325423 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of ALPL mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of BGLAP mRNA] CTD PMID:21910061 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Slc51b SLC51 subunit beta multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLC51B mRNA] CTD PMID:28549656 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLCO1A4 mRNA] CTD PMID:28549656 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of SOD3 mRNA] CTD PMID:23341968 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA] CTD PMID:21910061 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]] CTD PMID:28213090 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of and results in increased secretion of TNF protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF mRNA]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; IRAK3 protein promotes the reaction [Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased expression of TNF protein]
18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of NFKB1 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of RELA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of VEGFA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
CTD PMID:21644799 PMID:24613819 PMID:28213090 PMID:28414158 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]] CTD PMID:28213090 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of VEGFA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA] CTD PMID:24613819 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO 18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:29444456 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
hyperforin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO hyperforin results in increased expression of ABCB1; hyperforin results in increased expression of ABCB1 mRNA
hyperforin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]
CTD PMID:15266218 PMID:16005588 PMID:24259679 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO hyperforin results in increased expression of ALAS1 mRNA CTD PMID:24259679 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO hyperforin results in increased expression of BAK1 protein CTD PMID:32485087 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions
EXP
ISO
hyperforin results in decreased expression of BAX mRNA
hyperforin results in increased expression of BAX protein
hyperforin inhibits the reaction [aluminum maltolate results in increased expression of BAX mRNA]
CTD PMID:30481499 PMID:32485087 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
hyperforin inhibits the reaction [aluminum maltolate results in decreased expression of BCL2 mRNA]
hyperforin results in increased expression of BCL2 mRNA
CTD PMID:30481499 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
decreases expression
ISO
EXP
hyperforin inhibits the reaction [aluminum maltolate results in increased activity of CASP3 protein]; hyperforin inhibits the reaction [aluminum maltolate results in increased expression of CASP3 mRNA]
hyperforin results in increased cleavage of CASP3 protein
hyperforin results in decreased expression of CASP3 mRNA
hyperforin inhibits the reaction [aluminum maltolate results in increased activity of CASP3 protein]; hyperforin inhibits the reaction [aluminum maltolate results in increased expression of CASP3 mRNA]; hyperforin inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]
CTD PMID:30481499 PMID:32485087 PMID:36640868 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases cleavage ISO hyperforin results in increased cleavage of CASP8 protein CTD PMID:32485087 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO hyperforin results in decreased expression of CCND1 protein CTD PMID:32485087 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO hyperforin results in decreased expression of CFLAR protein CTD PMID:32485087 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
decreases expression
EXP
ISO
hyperforin inhibits the reaction [aluminum maltolate results in increased expression of CYCS protein]
hyperforin results in decreased expression of CYCS protein
CTD PMID:30481499 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO hyperforin inhibits the reaction [CYP1A1 protein affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol]
hyperforin results in decreased activity of CYP1A1 protein
CTD PMID:14633740 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO hyperforin results in increased expression of CYP24A1 mRNA CTD PMID:15630458 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO hyperforin results in increased expression of CYP2B6 mRNA CTD PMID:24259679 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression
multiple interactions
ISO hyperforin results in increased expression of CYP2C9 mRNA
hyperforin results in increased expression of and results in increased activity of CYP2C9 protein; NR1I2 protein affects the reaction [hyperforin results in increased expression of CYP2C9 mRNA]
CTD PMID:14600250 PMID:15100173 PMID:24259679 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
decreases activity
ISO hyperforin results in increased expression of CYP3A4; hyperforin results in increased expression of CYP3A4 mRNA
hyperforin results in increased expression of and results in increased activity of CYP3A4 protein
hyperforin results in decreased activity of CYP3A4 protein
CTD PMID:15100173 PMID:15266218 PMID:16005588 PMID:16442130 PMID:17954527 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO hyperforin results in increased expression of CYP3A5 mRNA CTD PMID:24259679 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO hyperforin results in decreased expression of CYP7A1 mRNA CTD PMID:24259679 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO hyperforin results in decreased phosphorylation of EGFR protein CTD PMID:32485087 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO hyperforin results in increased expression of FAS protein CTD PMID:32485087 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO hyperforin results in increased expression of FASLG protein CTD PMID:32485087 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO hyperforin results in increased expression of ICAM1 mRNA CTD PMID:15622447 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO hyperforin promotes the reaction [JUN protein binds to CXCL8 promoter] CTD PMID:15622447 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases phosphorylation
ISO hyperforin results in increased phosphorylation of MAPK1 protein
hyperforin results in decreased phosphorylation of MAPK1 protein
CTD PMID:15622447 PMID:32485087 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases phosphorylation
ISO hyperforin results in increased phosphorylation of MAPK3 protein
hyperforin results in decreased phosphorylation of MAPK3 protein
CTD PMID:15622447 PMID:32485087 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO hyperforin results in decreased expression of MCL1 protein CTD PMID:32485087 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases response to substance
affects binding
increases activity
ISO [NR1I2 protein co-treated with hyperforin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to hyperforin] which results in decreased expression of SLC22A1 mRNA; hyperforin binds to and results in increased activity of NR1I2 protein; hyperforin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]; NR1I2 protein affects the reaction [hyperforin results in increased expression of CYP2C9 mRNA]; NR1I2 protein promotes the reaction [hyperforin results in increased abundance of Lipids]
hyperforin binds to NR1I2 protein
hyperforin results in increased activity of NR1I2 protein
CTD PMID:14600250 PMID:15630458 PMID:15856409 PMID:20079722 PMID:26187274 More... NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO hyperforin results in increased expression of POR mRNA CTD PMID:24259679 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression
multiple interactions
ISO hyperforin results in decreased expression of SLC22A1 protein
[NR1I2 protein co-treated with hyperforin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to hyperforin] which results in decreased expression of SLC22A1 mRNA; hyperforin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]
CTD PMID:26920453 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions EXP hyperforin inhibits the reaction [Propofol results in decreased expression of TRPC6 protein] CTD PMID:36640868 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO hyperforin results in increased expression of UGT1A1 mRNA CTD PMID:24259679 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO hyperforin results in decreased expression of XIAP protein CTD PMID:32485087 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
irofulven term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases response to substance ISO ERCC6 mutant form results in increased susceptibility to irofulven CTD PMID:28076683 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO irofulven results in decreased activity of GSR protein CTD PMID:19668867 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
ketamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression EXP Ketamine results in increased expression of ABCA1 mRNA CTD PMID:20080153 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO ABCB1A protein affects the susceptibility to [Pentobarbital co-treated with Ketamine] CTD PMID:17959987 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Ketamine results in increased expression of ABCG1 mRNA CTD PMID:20080153 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abhd16a abhydrolase domain containing 16A, phospholipase increases expression EXP Ketamine results in increased expression of ABHD16A mRNA CTD PMID:20080153 NCBI chr20:3,719,089...3,733,952
Ensembl chr20:3,719,091...3,733,927
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase decreases expression EXP Ketamine results in decreased expression of ABHD5 mRNA CTD PMID:20080153 NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression EXP Ketamine results in decreased expression of ACAT2 mRNA CTD PMID:20080153 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acbd3 acyl-CoA binding domain containing 3 decreases expression EXP Ketamine results in decreased expression of ACBD3 mRNA CTD PMID:20080153 NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380
JBrowse link
G Acbd5 acyl-CoA binding domain containing 5 decreases expression EXP Ketamine results in decreased expression of ACBD5 mRNA CTD PMID:20080153 NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
JBrowse link
G Ace angiotensin I converting enzyme increases expression EXP Ketamine results in increased expression of ACE mRNA CTD PMID:20080153 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic decreases expression EXP Ketamine results in decreased expression of ACP6 mRNA CTD PMID:20080153 NCBI chr 2:184,711,975...184,733,067
Ensembl chr 2:184,711,619...184,733,017
JBrowse link
G Acr acrosin increases expression EXP Ketamine results in increased expression of ACR mRNA CTD PMID:20080153 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474
JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 increases expression EXP Ketamine results in increased expression of ACSBG1 mRNA CTD PMID:20080153 NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
ISO 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of ACTA2 protein]
Ketamine results in increased expression of ACTA2 mRNA; Ketamine results in increased expression of ACTA2 protein
CTD PMID:28331066 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP Ketamine results in decreased expression of ACTG2 mRNA CTD PMID:20080153 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Acvr1c activin A receptor type 1C decreases expression EXP Ketamine results in decreased expression of ACVR1C mRNA CTD PMID:20080153 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression EXP Ketamine results in increased expression of ADAP2 mRNA CTD PMID:20080153 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
JBrowse link
G Adck2 aarF domain containing kinase 2 decreases expression EXP Ketamine results in decreased expression of ADCK2 mRNA CTD PMID:20080153 NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608
JBrowse link
G Adcy8 adenylate cyclase 8 decreases expression EXP Ketamine results in decreased expression of ADCY8 mRNA CTD PMID:20080153 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
JBrowse link
G Adcy9 adenylate cyclase 9 increases expression EXP Ketamine results in increased expression of ADCY9 mRNA CTD PMID:20080153 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 decreases expression EXP Ketamine results in decreased expression of ADCYAP1 mRNA CTD PMID:20080153 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Add2 adducin 2 decreases expression EXP Ketamine results in decreased expression of ADD2 mRNA CTD PMID:20080153 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 increases expression EXP Ketamine results in increased expression of ADGRB2 mRNA CTD PMID:20080153 NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
JBrowse link
G Afp alpha-fetoprotein increases expression EXP Ketamine results in increased expression of AFP mRNA CTD PMID:20080153 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agt angiotensinogen decreases expression
increases expression
ISO
EXP
Ketamine results in decreased expression of AGT protein
Ketamine results in increased expression of AGT mRNA
CTD PMID:6349867 PMID:20080153 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtrap angiotensin II receptor-associated protein increases expression EXP Ketamine results in increased expression of AGTRAP mRNA CTD PMID:20080153 NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression EXP Ketamine results in decreased expression of AHR mRNA CTD PMID:20080153 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression
multiple interactions
EXP Ketamine results in decreased expression of AIF1 mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of AIF1 mRNA]
CTD PMID:31823199 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression EXP Ketamine results in decreased expression of AKAP9 mRNA CTD PMID:20080153 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Alb albumin increases expression EXP Ketamine results in increased expression of ALB mRNA CTD PMID:20080153 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression EXP Ketamine results in decreased expression of ALDH18A1 mRNA CTD PMID:20080153 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP Ketamine results in increased expression of ALDOC mRNA CTD PMID:20080153 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein decreases expression EXP Ketamine results in decreased expression of ALMS1 mRNA CTD PMID:20080153 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression EXP Ketamine results in decreased expression of AMIGO2 mRNA CTD PMID:20080153 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
JBrowse link
G Anapc1 anaphase promoting complex subunit 1 increases expression EXP Ketamine results in increased expression of ANAPC1 mRNA CTD PMID:20080153 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP Ketamine results in increased expression of ANGPTL4 mRNA CTD PMID:20080153 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankrd42 ankyrin repeat domain 42 decreases expression EXP Ketamine results in decreased expression of ANKRD42 mRNA CTD PMID:20080153 NCBI chr 1:146,648,080...146,691,086
Ensembl chr 1:146,648,080...146,691,108
JBrowse link
G Anxa11 annexin A11 increases expression EXP Ketamine results in increased expression of ANXA11 mRNA CTD PMID:20080153 NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Ketamine results in decreased expression of ANXA3 mRNA CTD PMID:20080153 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa4 annexin A4 increases expression EXP Ketamine results in increased expression of ANXA4 mRNA CTD PMID:20080153 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa5 annexin A5 decreases expression EXP Ketamine results in decreased expression of ANXA5 mRNA CTD PMID:20080153 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 multiple interactions ISO Ketamine inhibits the reaction [NTRK2 protein binds to AP2M1 protein] CTD PMID:31631060 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 decreases expression EXP Ketamine results in decreased expression of AP3M1 mRNA CTD PMID:20080153 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 decreases expression EXP Ketamine results in decreased expression of AP5M1 mRNA CTD PMID:20080153 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 decreases expression EXP Ketamine results in decreased expression of APEX2 mRNA CTD PMID:20080153 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439
JBrowse link
G Aplf aprataxin and PNKP like factor decreases expression EXP Ketamine results in decreased expression of APLF mRNA CTD PMID:20080153 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
JBrowse link
G Apmap adipocyte plasma membrane associated protein increases expression EXP Ketamine results in increased expression of APMAP mRNA CTD PMID:20080153 NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341
JBrowse link
G Apoe apolipoprotein E decreases response to substance
increases expression
ISO
EXP
APOE results in decreased susceptibility to Ketamine
Ketamine results in increased expression of APOE mRNA
CTD PMID:9778666 PMID:20080153 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein increases expression
multiple interactions
ISO Ketamine results in increased expression of APP mRNA
Ketamine results in decreased expression of and results in increased cleavage of APP protein; Monensin inhibits the reaction [Ketamine results in decreased expression of and results in increased cleavage of APP protein]
[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40); [Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42); Ketamine results in decreased expression of and results in increased cleavage of APP protein; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40)]; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42)]
CTD PMID:35378374 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 decreases expression EXP Ketamine results in decreased expression of APPBP2 mRNA CTD PMID:20080153 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
JBrowse link
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 decreases expression EXP Ketamine results in decreased expression of ARFGEF1 mRNA CTD PMID:20080153 NCBI chr 5:8,982,061...9,076,326
Ensembl chr 5:8,981,540...9,076,326
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression EXP Ketamine results in decreased expression of ARHGAP5 mRNA CTD PMID:20080153 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 decreases expression EXP Ketamine results in decreased expression of ARIH1 mRNA CTD PMID:20080153 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
JBrowse link
G Arl6 ADP-ribosylation factor like GTPase 6 decreases expression EXP Ketamine results in decreased expression of ARL6 mRNA CTD PMID:20080153 NCBI chr11:40,711,878...40,738,254
Ensembl chr11:40,712,022...40,737,937
JBrowse link
G Arl6ip6 ADP ribosylation factor like GTPase 6 interacting protein 6 decreases expression EXP Ketamine results in decreased expression of ARL6IP6 mRNA CTD PMID:20080153 NCBI chr 3:37,689,994...37,720,358
Ensembl chr 3:37,690,382...37,718,018
JBrowse link
G Armc10 armadillo repeat containing 10 decreases expression EXP Ketamine results in decreased expression of ARMC10 mRNA CTD PMID:20080153 NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548
JBrowse link
G Art3 ADP-ribosyltransferase 3 increases expression EXP Ketamine results in increased expression of ART3 mRNA CTD PMID:20080153 NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 decreases expression EXP Ketamine results in decreased expression of ASCL1 mRNA CTD PMID:20080153 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Asic4 acid sensing ion channel subunit family member 4 increases expression EXP Ketamine results in increased expression of ASIC4 mRNA CTD PMID:20080153 NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900
JBrowse link
G Aspdh aspartate dehydrogenase domain containing increases expression EXP Ketamine results in increased expression of ASPDH mRNA CTD PMID:20080153 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Ketamine results in increased expression of ATF4 mRNA CTD PMID:35728656 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Ketamine results in increased expression of ATF6 mRNA CTD PMID:35728656 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg12 autophagy related 12 increases expression EXP Ketamine results in increased expression of ATG12 mRNA CTD PMID:20080153 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atp13a4 ATPase 13A4 increases expression EXP Ketamine results in increased expression of ATP13A4 mRNA CTD PMID:20080153 NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Ketamine results in increased expression of ATP1A1 mRNA CTD PMID:20080153 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression EXP Ketamine results in increased expression of ATP1A2 mRNA CTD PMID:20080153 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 increases expression EXP Ketamine results in increased expression of ATP1A3 mRNA CTD PMID:20080153 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression EXP Ketamine results in increased expression of ATP6V0A1 mRNA CTD PMID:20080153 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 increases expression EXP Ketamine results in increased expression of ATP6V1C2 mRNA CTD PMID:20080153 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
JBrowse link
G Atp7a ATPase copper transporting alpha decreases expression EXP Ketamine results in decreased expression of ATP7A mRNA CTD PMID:20080153 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G B4gat1 beta-1,4-glucuronyltransferase 1 increases expression EXP Ketamine results in increased expression of B4GAT1 mRNA CTD PMID:20080153 NCBI chr 1:202,343,268...202,345,490
Ensembl chr 1:202,343,240...202,346,065
JBrowse link
G Bace1 beta-secretase 1 increases expression
multiple interactions
ISO Ketamine results in increased expression of BACE1 protein
Ketamine results in increased expression of and affects the localization of BACE1 protein; Monensin inhibits the reaction [Ketamine results in increased expression of and affects the localization of BACE1 protein]
CTD PMID:35378374 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bag3 BAG cochaperone 3 increases expression EXP Ketamine results in increased expression of BAG3 mRNA CTD PMID:20080153 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 increases expression EXP Ketamine results in increased expression of BAIAP2 mRNA CTD PMID:20080153 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Banp Btg3 associated nuclear protein decreases expression EXP Ketamine results in decreased expression of BANP mRNA CTD PMID:20080153 NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
multiple interactions
increases expression
ISO
EXP
Ketamine affects the localization of BAX protein
Curcumin inhibits the reaction [Ketamine results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX protein]
Ketamine results in increased expression of BAX mRNA; Ketamine results in increased expression of BAX protein
CTD PMID:18456338 PMID:19001360 PMID:25937004 PMID:33536391 PMID:36305173 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha increases expression EXP Ketamine results in increased expression of BCKDHA mRNA CTD PMID:20080153 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
Curcumin affects the reaction [Ketamine results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 protein]
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]
Ketamine results in decreased expression of BCL2 mRNA; Ketamine results in decreased expression of BCL2 protein
CTD PMID:33536391 PMID:36305173 PMID:36907275 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bclaf3 BCLAF1 and THRAP3 family member 3 decreases expression EXP Ketamine results in decreased expression of BCLAF3 mRNA CTD PMID:20080153 NCBI chr  X:35,257,228...35,328,883
Ensembl chr  X:35,263,576...35,328,816
JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 decreases expression EXP Ketamine results in decreased expression of BCORL1 mRNA CTD PMID:20080153 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087
JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone decreases expression EXP Ketamine results in decreased expression of BCS1L mRNA CTD PMID:20080153 NCBI chr 9:76,164,925...76,168,940
Ensembl chr 9:76,164,932...76,168,938
JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression ISO Ketamine results in increased expression of BDKRB1 mRNA; Ketamine results in increased expression of BDKRB1 protein CTD PMID:27638051 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
EXP
ISO
Ketamine inhibits the reaction [Isoflurophate results in decreased expression of BDNF protein]; Ketamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA]
Ketamine results in increased expression of BDNF protein
Sirolimus inhibits the reaction [Ketamine results in increased expression of BDNF protein]
CTD PMID:8635431 PMID:32592718 PMID:33022268 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 increases expression ISO Ketamine results in increased expression of BECN1 protein CTD PMID:34487425 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 decreases expression EXP Ketamine results in decreased expression of BHLHE22 mRNA CTD PMID:20080153 NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP Ketamine results in increased expression of BHLHE40 mRNA CTD PMID:20080153 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression EXP Ketamine results in increased expression of BHLHE41 mRNA CTD PMID:20080153 NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger decreases expression EXP Ketamine results in decreased expression of BMI1 mRNA CTD PMID:20080153 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression EXP Ketamine results in decreased expression of BNIP3 mRNA CTD PMID:20080153 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of BRAF protein] CTD PMID:19540866 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brinp2 BMP/retinoic acid inducible neural specific 2 increases expression EXP Ketamine results in increased expression of BRINP2 mRNA CTD PMID:20080153 NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP Ketamine results in decreased expression of BTG1 mRNA CTD PMID:20080153 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression EXP Ketamine results in decreased expression of BUB1B mRNA CTD PMID:20080153 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C17h5orf24 similar to human chromosome 5 open reading frame 24 decreases expression EXP Ketamine results in decreased expression of C17H5ORF24 mRNA CTD PMID:20080153 NCBI chr17:8,923,041...8,932,958
Ensembl chr17:8,922,675...8,933,356
JBrowse link
G C1qa complement C1q A chain increases expression EXP Ketamine results in increased expression of C1QA mRNA CTD PMID:20080153 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C1qb complement C1q B chain increases expression EXP Ketamine results in increased expression of C1QB mRNA CTD PMID:20080153 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G C1qc complement C1q C chain increases expression
multiple interactions
decreases expression
EXP Ketamine results in increased expression of C1QC mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of C1QC mRNA]
CTD PMID:20080153 PMID:31823199 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G C2 complement C2 increases expression EXP Ketamine results in increased expression of C2 mRNA CTD PMID:20080153 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G C2cd2l C2CD2-like increases expression EXP Ketamine results in increased expression of C2CD2L mRNA CTD PMID:20080153 NCBI chr 8:44,648,074...44,658,856
Ensembl chr 8:44,648,079...44,658,340
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression EXP Ketamine results in increased expression of C2CD4B mRNA CTD PMID:20080153 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
JBrowse link
G C4bpb complement component 4 binding protein, beta increases expression EXP Ketamine results in increased expression of C4BPB mRNA CTD PMID:20080153 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression EXP Ketamine results in decreased expression of CAAP1 mRNA CTD PMID:20080153 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 increases expression EXP Ketamine results in increased expression of CABCOCO1 mRNA CTD PMID:20080153 NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725
JBrowse link
G Cabp7 calcium binding protein 7 increases expression EXP Ketamine results in increased expression of CABP7 mRNA CTD PMID:20080153 NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 increases expression EXP Ketamine results in increased expression of CACNG2 mRNA CTD PMID:20080153 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Calb2 calbindin 2 increases expression EXP Ketamine results in increased expression of CALB2 mRNA CTD PMID:20080153 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 increases expression EXP Ketamine results in increased expression of CAMKK1 mRNA CTD PMID:20080153 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498
JBrowse link
G Cand2 cullin-associated and neddylation-dissociated 2 (putative) decreases expression EXP Ketamine results in decreased expression of CAND2 mRNA CTD PMID:20080153 NCBI chr 4:148,835,050...148,864,039
Ensembl chr 4:148,835,053...148,863,153
JBrowse link
G Cant1 calcium activated nucleotidase 1 increases expression EXP Ketamine results in increased expression of CANT1 mRNA CTD PMID:20080153 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Car4 carbonic anhydrase 4 increases expression EXP Ketamine results in increased expression of CAR4 mRNA CTD PMID:20080153 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Car7 carbonic anhydrase 7 increases expression EXP Ketamine results in increased expression of CAR7 mRNA CTD PMID:20080153 NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Ketamine results in increased activity of CASP3 protein
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]
Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased cleavage of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of CASP3 mRNA]
Ketamine results in increased expression of CASP3 mRNA; Ketamine results in increased expression of CASP3 protein; Ketamine results in increased expression of CASP3 protein modified form
CTD PMID:17920787 PMID:19001360 PMID:25937004 PMID:33536391 PMID:36305173 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 increases activity ISO Ketamine results in increased activity of CASP6 protein CTD PMID:19001360 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp9 caspase 9 increases activity
increases expression
ISO
EXP
Ketamine results in increased activity of CASP9 protein
Ketamine results in increased expression of CASP9 mRNA
CTD PMID:19001360 PMID:20080153 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Ketamine results in decreased activity of CAT protein
TRPV4 protein affects the reaction [Ketamine results in decreased activity of CAT protein]
CTD PMID:33536391 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbr3 carbonyl reductase 3 decreases expression EXP Ketamine results in decreased expression of CBR3 mRNA CTD PMID:20080153 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Cbx1 chromobox 1 decreases expression EXP Ketamine results in decreased expression of CBX1 mRNA CTD PMID:20080153 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Cbx7 chromobox 7 increases expression EXP Ketamine results in increased expression of CBX7 mRNA CTD PMID:20080153 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccdc115 coiled-coil domain containing 115 increases expression EXP Ketamine results in increased expression of CCDC115 mRNA CTD PMID:20080153 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946
JBrowse link
G Ccdc50 coiled-coil domain containing 50 decreases expression EXP Ketamine results in decreased expression of CCDC50 mRNA CTD PMID:20080153 NCBI chr11:73,332,798...73,395,333
Ensembl chr11:73,334,248...73,395,150
JBrowse link
G Ccdc85a coiled-coil domain containing 85A decreases expression EXP Ketamine results in decreased expression of CCDC85A mRNA CTD PMID:20080153 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058
JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression EXP Ketamine results in decreased expression of CCDC90B mRNA CTD PMID:20080153 NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP Ketamine results in decreased expression of CCNA2 mRNA CTD PMID:20080153 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Ketamine results in decreased expression of CCND1 mRNA CTD PMID:20080153 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccndbp1 cyclin D1 binding protein 1 decreases expression EXP Ketamine results in decreased expression of CCNDBP1 mRNA CTD PMID:20080153 NCBI chr 3:107,962,402...107,974,234
Ensembl chr 3:107,962,261...107,974,233
JBrowse link
G Ccpg1 cell cycle progression 1 increases expression EXP Ketamine results in increased expression of CCPG1 mRNA CTD PMID:20080153 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression EXP Ketamine results in increased expression of CCR5 mRNA CTD PMID:20080153 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Ccsap centriole, cilia and spindle-associated protein increases expression EXP Ketamine results in increased expression of CCSAP mRNA CTD PMID:20080153 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
JBrowse link
G Cd24 CD24 molecule decreases expression EXP Ketamine results in decreased expression of CD24 mRNA CTD PMID:20080153 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd38 CD38 molecule increases expression EXP Ketamine results in increased expression of CD38 mRNA CTD PMID:20080153 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd83 CD83 molecule increases expression EXP Ketamine results in increased expression of CD83 mRNA CTD PMID:20080153 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression EXP Ketamine results in decreased expression of CDC42EP3 mRNA CTD PMID:20080153 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdc6 cell division cycle 6 decreases expression EXP Ketamine results in decreased expression of CDC6 mRNA CTD PMID:20080153 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression EXP Ketamine results in decreased expression of CDCA7 mRNA CTD PMID:20080153 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions
EXP
ISO
Ketamine results in decreased expression of CDH1 protein
Ketamine results in decreased expression of CDH1 mRNA; Ketamine results in decreased expression of CDH1 protein
2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in decreased expression of CDH1 protein]
CTD PMID:28331066 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh11 cadherin 11 decreases expression EXP Ketamine results in decreased expression of CDH11 mRNA CTD PMID:20080153 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdh7 cadherin 7 decreases expression EXP Ketamine results in decreased expression of CDH7 mRNA CTD PMID:20080153 NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Ketamine results in decreased expression of CDK1 mRNA CTD PMID:20080153 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk14 cyclin-dependent kinase 14 decreases expression EXP Ketamine results in decreased expression of CDK14 mRNA CTD PMID:20080153 NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor affects expression ISO Ketamine affects the expression of CDNF mRNA CTD PMID:35728656 NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Ketamine results in increased expression of CEBPB mRNA CTD PMID:20080153 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cenpc centromere protein C decreases expression EXP Ketamine results in decreased expression of CENPC1 mRNA CTD PMID:20080153 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
JBrowse link
G Cep70 centrosomal protein 70 decreases expression EXP Ketamine results in decreased expression of CEP70 mRNA CTD PMID:20080153 NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855
JBrowse link
G Cfap126 cilia and flagella associated protein 126 increases expression EXP Ketamine results in increased expression of CFAP126 mRNA CTD PMID:20080153 NCBI chr13:83,526,657...83,542,552
Ensembl chr13:83,526,657...83,542,552
JBrowse link
G Cfap410 cilia and flagella associated protein 410 increases expression EXP Ketamine results in increased expression of CFAP410 mRNA CTD PMID:20080153 NCBI chr20:10,687,863...10,694,736
Ensembl chr20:10,687,863...10,694,737
JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression EXP Ketamine results in increased expression of CHI3L1 mRNA CTD PMID:20080153 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression EXP Ketamine results in decreased expression of CHORDC1 mRNA CTD PMID:20080153 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 increases expression EXP Ketamine results in increased expression of CHPF2 mRNA CTD PMID:20080153 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM1 protein] CTD PMID:12456425 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM2 protein] CTD PMID:12456425 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions ISO Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM3 protein] CTD PMID:12456425 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Ciao3 cytosolic iron-sulfur assembly component 3 increases expression EXP Ketamine results in increased expression of CIAO3 mRNA CTD PMID:20080153 NCBI chr10:14,795,888...14,804,953
Ensembl chr10:14,795,961...14,804,950
JBrowse link
G Cldn11 claudin 11 increases expression EXP Ketamine results in increased expression of CLDN11 mRNA CTD PMID:20080153 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Clec2l C-type lectin domain family 2, member L increases expression EXP Ketamine results in increased expression of CLEC2L mRNA CTD PMID:20080153 NCBI chr 4:67,392,118...67,414,539
Ensembl chr 4:67,397,873...67,414,537
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 increases expression EXP Ketamine results in increased expression of CLEC4A3 mRNA CTD PMID:20080153 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression EXP Ketamine results in decreased expression of CLK1 mRNA CTD PMID:20080153 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clmp CXADR-like membrane protein decreases expression EXP Ketamine results in decreased expression of CLMP mRNA CTD PMID:20080153 NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838
JBrowse link
G Clu clusterin increases expression EXP Ketamine results in increased expression of CLU mRNA CTD PMID:20080153 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cmtm5 CKLF-like MARVEL transmembrane domain containing 5 increases expression EXP Ketamine results in increased expression of CMTM5 mRNA CTD PMID:20080153 NCBI chr15:28,412,624...28,415,304
Ensembl chr15:28,412,624...28,415,287
JBrowse link
G Cmtm8 CKLF-like MARVEL transmembrane domain containing 8 increases expression EXP Ketamine results in increased expression of CMTM8 mRNA CTD PMID:20080153 NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083
JBrowse link
G Cnksr3 Cnksr family member 3 increases expression EXP Ketamine results in increased expression of CNKSR3 mRNA CTD PMID:20080153 NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Ketamine results in decreased expression of CNR1 mRNA CTD PMID:20080153 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Coa4 cytochrome c oxidase assembly factor 4 homolog decreases expression EXP Ketamine results in decreased expression of COA4 mRNA CTD PMID:20080153 NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174
JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 increases expression EXP Ketamine results in increased expression of COA7 mRNA CTD PMID:20080153 NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199
JBrowse link
G Cog6 component of oligomeric golgi complex 6 decreases expression EXP Ketamine results in decreased expression of COG6 mRNA CTD PMID:20080153 NCBI chr 2:137,062,127...137,099,176
Ensembl chr 2:137,061,346...137,099,190
JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression EXP Ketamine results in decreased expression of COL11A1 mRNA CTD PMID:20080153 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Commd5 COMM domain containing 5 increases expression EXP Ketamine results in increased expression of COMMD5 mRNA CTD PMID:20080153 NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764
JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Ketamine results in increased expression of COMT mRNA CTD PMID:20080153 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coq8a coenzyme Q8A increases expression EXP Ketamine results in increased expression of COQ8A mRNA CTD PMID:20080153 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
JBrowse link
G Cort cortistatin increases expression EXP Ketamine results in increased expression of CORT mRNA CTD PMID:20080153 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression EXP Ketamine results in increased expression of COX6A2 mRNA CTD PMID:20080153 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cracdl CRACD like increases expression EXP Ketamine results in increased expression of CRACDL mRNA CTD PMID:20080153 NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086
JBrowse link
G Crcp CGRP receptor component increases expression EXP Ketamine results in increased expression of CRCP mRNA CTD PMID:20080153 NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP Ketamine results in increased expression of CREG1 mRNA CTD PMID:20080153 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 decreases expression EXP Ketamine results in decreased expression of CRELD2 mRNA CTD PMID:20080153 NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
JBrowse link
G Crh corticotropin releasing hormone decreases expression EXP Ketamine results in decreased expression of CRH mRNA CTD PMID:20080153 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crls1 cardiolipin synthase 1 decreases expression EXP Ketamine results in decreased expression of CRLS1 mRNA CTD PMID:20080153 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
JBrowse link
G Crtac1 cartilage acidic protein 1 increases expression EXP Ketamine results in increased expression of CRTAC1 mRNA CTD PMID:20080153 NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421
JBrowse link
G Cryab crystallin, alpha B increases expression EXP Ketamine results in increased expression of CRYAB mRNA CTD PMID:20080153 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
EXP Ketamine results in increased expression of CTNNB1 protein
Chir 99021 promotes the reaction [Ketamine results in increased expression of CTNNB1 protein]
CTD PMID:36334642 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctse cathepsin E increases expression EXP Ketamine results in increased expression of CTSE mRNA CTD PMID:20080153 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
JBrowse link
G Ctsk cathepsin K increases expression EXP Ketamine results in increased expression of CTSK mRNA CTD PMID:20080153 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Ctss cathepsin S increases expression EXP Ketamine results in increased expression of CTSS mRNA CTD PMID:20080153 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cttnbp2nl CTTNBP2 N-terminal like decreases expression EXP Ketamine results in decreased expression of CTTNBP2NL mRNA CTD PMID:20080153 NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Ketamine results in increased expression of CX3CL1 mRNA CTD PMID:20080153 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxxc4 CXXC finger protein 4 decreases expression EXP Ketamine results in decreased expression of CXXC4 mRNA CTD PMID:20080153 NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression EXP Ketamine results in increased expression of CYB5R3 mRNA CTD PMID:20080153 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Ketamine results in increased expression of CYBA CTD PMID:18063801 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO Ketamine results in increased expression of CYBB CTD PMID:18063801 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP Ketamine results in increased expression of CYP11A1 mRNA CTD PMID:20080153 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Ketamine results in increased expression of CYP1A1 protein CTD PMID:16076768 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Ketamine results in increased expression of CYP2B1 protein CTD PMID:16076768 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Ketamine results in increased expression of CYP2E1 protein CTD PMID:16076768 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
decreases expression
multiple interactions
EXP
ISO
Ketamine results in increased expression of CYP3A2 protein
Ketamine results in decreased expression of CYP3A4 mRNA
Ketamine results in decreased expression of and results in decreased activity of CYP3A4 protein
CTD PMID:16076768 PMID:18845661 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Ketamine results in increased expression of CYP3A23-3A1 protein CTD PMID:16076768 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 increases expression EXP Ketamine results in increased expression of CYP46A1 mRNA CTD PMID:20080153 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Cyth4 cytohesin 4 decreases expression
multiple interactions
EXP Ketamine results in decreased expression of CYTH4 mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of CYTH4 mRNA]
CTD PMID:31823199 NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741
JBrowse link
G Daglb diacylglycerol lipase, beta decreases expression EXP Ketamine results in decreased expression of DAGLB mRNA CTD PMID:20080153 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
JBrowse link
G Dbndd1 dysbindin domain containing 1 decreases expression EXP Ketamine results in decreased expression of DBNDD1 mRNA CTD PMID:20080153 NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 decreases expression EXP Ketamine results in decreased expression of DCAF13 mRNA CTD PMID:20080153 NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142
JBrowse link
G Dctd dCMP deaminase decreases expression EXP Ketamine results in decreased expression of DCTD mRNA CTD PMID:20080153 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Ketamine results in increased expression of DDIT3 mRNA
Ketamine results in increased expression of DDIT3 protein
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]
CTD PMID:35728656 PMID:36907275 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx31 DEAD-box helicase 31 decreases expression EXP Ketamine results in decreased expression of DDX31 mRNA CTD PMID:20080153 NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873
JBrowse link
G Defb1 defensin beta 1 decreases expression EXP Ketamine results in decreased expression of DEFB1 mRNA CTD PMID:20080153 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dennd2b DENN domain containing 2B increases expression EXP Ketamine results in increased expression of DENND2B mRNA CTD PMID:20080153 NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression EXP Ketamine results in increased expression of DGAT2 mRNA CTD PMID:20080153 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) decreases expression EXP Ketamine results in decreased expression of DHODH mRNA CTD PMID:20080153 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression EXP Ketamine results in decreased expression of DHX36 mRNA CTD PMID:20080153 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dipk1a divergent protein kinase domain 1A increases expression EXP Ketamine results in increased expression of DIPK1A mRNA CTD PMID:20080153 NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 decreases expression
multiple interactions
increases expression
ISO Ketamine results in decreased expression of DLG4 protein
Ketamine inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein]; Sirolimus inhibits the reaction [Ketamine results in increased expression of DLG4 protein]
CTD PMID:31470060 PMID:33022268 PMID:33872575 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dlx5 distal-less homeobox 5 decreases expression EXP Ketamine results in decreased expression of DLX5 mRNA CTD PMID:20080153 NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407
JBrowse link
G Dmac1 distal membrane arm assembly component 1 decreases expression EXP Ketamine results in decreased expression of DMAC1 mRNA CTD PMID:20080153 NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757
JBrowse link
G Dmrtc1a DMRT-like family C1a increases expression EXP Ketamine results in increased expression of DMRTC1A mRNA CTD PMID:20080153 NCBI chr  X:67,822,187...67,852,572
Ensembl chr  X:67,822,113...67,852,571
JBrowse link
G Dmtf1 cyclin D binding myb-like transcription factor 1 decreases expression EXP Ketamine results in decreased expression of DMTF1 mRNA CTD PMID:20080153 NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 decreases expression EXP Ketamine results in decreased expression of DNAJB14 mRNA CTD PMID:20080153 NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression EXP Ketamine results in decreased expression of DNAJC15 mRNA CTD PMID:20080153 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
JBrowse link
G Dnm1 dynamin 1 increases expression EXP Ketamine results in increased expression of DNM1 mRNA CTD PMID:20080153 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression EXP Ketamine results in decreased expression of DNMT3B mRNA CTD PMID:20080153 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dock11 dedicator of cytokinesis 11 decreases expression EXP Ketamine results in decreased expression of DOCK11 mRNA CTD PMID:20080153 NCBI chr  X:115,131,720...115,314,854
Ensembl chr  X:115,131,909...115,314,854
JBrowse link
G Dph5 diphthamide biosynthesis 5 decreases expression EXP Ketamine results in decreased expression of DPH5 mRNA CTD PMID:20080153 NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression EXP Ketamine results in decreased expression of DPYSL3 mRNA CTD PMID:20080153 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP Ketamine binds to Drd2 protein RGD PMID:15852061 RGD:1581406 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 decreases expression EXP Ketamine results in decreased expression of DTX4 mRNA CTD PMID:20080153 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression EXP Ketamine results in decreased expression of DUSP11 mRNA CTD PMID:20080153 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
JBrowse link
G Dusp22 dual specificity phosphatase 22 increases expression EXP Ketamine results in increased expression of DUSP22 mRNA CTD PMID:20080153 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
JBrowse link
G Dync2i2 dynein 2 intermediate chain 2 decreases expression EXP Ketamine results in decreased expression of DYNC2I2 mRNA CTD PMID:20080153 NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial decreases expression EXP Ketamine results in decreased expression of EARS2 mRNA CTD PMID:20080153 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression EXP Ketamine results in decreased expression of EBP mRNA CTD PMID:20080153 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G Ebpl EBP like decreases expression EXP Ketamine results in decreased expression of EBPL mRNA CTD PMID:20080153 NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression EXP Ketamine results in increased expression of ECHS1 protein CTD PMID:18504422 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression EXP Ketamine results in decreased expression of ECT2 mRNA CTD PMID:20080153 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Edc3 enhancer of mRNA decapping 3 increases expression EXP Ketamine results in increased expression of EDC3 mRNA CTD PMID:20080153 NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression EXP Ketamine results in decreased expression of EEF2K mRNA CTD PMID:20080153 NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Efhb EF hand domain family, member B increases expression EXP Ketamine results in increased expression of EFHB mRNA CTD PMID:20080153 NCBI chr 9:6,372,191...6,441,678
Ensembl chr 9:6,372,194...6,441,919
JBrowse link
G Efna2 ephrin A2 decreases expression EXP Ketamine results in decreased expression of EFNA2 mRNA CTD PMID:20080153 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061
JBrowse link
G Egr4 early growth response 4 decreases expression EXP Ketamine results in decreased expression of EGR4 mRNA CTD PMID:20080153 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A decreases expression EXP Ketamine results in decreased expression of EIF1A mRNA CTD PMID:20080153 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
JBrowse link
G Eif4e3 eukaryotic translation initiation factor 4E family member 3 decreases expression EXP Ketamine results in decreased expression of EIF4E3 mRNA CTD PMID:20080153 NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808
JBrowse link
G Eno2 enolase 2 decreases expression EXP Ketamine results in decreased expression of ENO2 protein CTD PMID:18504422 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression EXP Ketamine results in increased expression of ENPP2 mRNA CTD PMID:20080153 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Entrep1 endosomal transmembrane epsin interactor 1 increases expression EXP Ketamine results in increased expression of ENTREP1 mRNA CTD PMID:20080153 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758
JBrowse link
G Ephx4 epoxide hydrolase 4 increases expression EXP Ketamine results in increased expression of EPHX4 mRNA CTD PMID:20080153 NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO Ketamine results in decreased expression of ERBB4 mRNA CTD PMID:20000043 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Erich1 glutamate-rich 1 decreases expression EXP Ketamine results in decreased expression of ERICH1 mRNA CTD PMID:20080153 NCBI chr16:75,501,322...75,569,129
Ensembl chr16:75,501,384...75,569,128
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression EXP Ketamine results in increased expression of ERMP1 mRNA CTD PMID:20080153 NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression EXP Ketamine results in increased expression of EZH1 mRNA CTD PMID:20080153 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression EXP Ketamine results in decreased expression of EZH2 mRNA CTD PMID:20080153 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fam110d family with sequence similarity 110, member D decreases expression EXP Ketamine results in decreased expression of FAM110D mRNA CTD PMID:20080153 NCBI chr 5:146,471,048...146,474,019
Ensembl chr 5:146,471,049...146,474,056
JBrowse link
G Fam120b family with sequence similarity 120 member B decreases expression EXP Ketamine results in decreased expression of FAM120B mRNA CTD PMID:20080153 NCBI chr 1:56,320,015...56,385,064
Ensembl chr 1:56,339,129...56,385,061
JBrowse link
G Fam136a family with sequence similarity 136, member A decreases expression EXP Ketamine results in decreased expression of FAM136A mRNA CTD PMID:20080153 NCBI chr 4:118,805,129...118,811,046
Ensembl chr 4:118,805,127...118,811,047
JBrowse link
G Fam180a family with sequence similarity 180, member A decreases expression EXP Ketamine results in decreased expression of FAM180A mRNA CTD PMID:20080153 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047
JBrowse link
G Fam210a family with sequence similarity 210, member A decreases expression EXP Ketamine results in decreased expression of FAM210A mRNA CTD PMID:20080153 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
JBrowse link
G Fam98a family with sequence similarity 98, member A decreases expression EXP Ketamine results in decreased expression of FAM98A mRNA CTD PMID:20080153 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742
JBrowse link
G Fat3 FAT atypical cadherin 3 decreases expression EXP Ketamine results in decreased expression of FAT3 mRNA CTD PMID:20080153 NCBI chr 8:12,691,470...13,274,336
Ensembl chr 8:12,694,019...13,273,135
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression EXP Ketamine results in decreased expression of FAT4 mRNA CTD PMID:20080153 NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707
JBrowse link
G Faxc failed axon connections homolog, metaxin like GST domain containing increases expression EXP Ketamine results in increased expression of FAXC mRNA CTD PMID:20080153 NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446
JBrowse link
G Fbl fibrillarin decreases expression EXP Ketamine results in decreased expression of FBL mRNA CTD PMID:20080153 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
JBrowse link
G Fblim1 filamin binding LIM protein 1 decreases expression EXP Ketamine results in decreased expression of FBLIM1 mRNA CTD PMID:20080153 NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
JBrowse link
G Fbxl22 F-box and leucine-rich repeat protein 22 increases expression EXP Ketamine results in increased expression of FBXL22 mRNA CTD PMID:20080153 NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685
JBrowse link
G Fbxo2 F-box protein 2 increases expression EXP Ketamine results in increased expression of FBXO2 mRNA CTD PMID:20080153 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
JBrowse link
G Fbxo34 F-box protein 34 increases expression EXP Ketamine results in increased expression of FBXO34 mRNA CTD PMID:20080153 NCBI chr15:20,719,395...20,787,905
Ensembl chr15:20,710,629...20,787,222
JBrowse link
G Fbxo8 F-box protein 8 increases expression EXP Ketamine results in increased expression of FBXO8 mRNA CTD PMID:20080153 NCBI chr16:33,665,305...33,711,215
Ensembl chr16:33,665,306...33,711,272
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP Ketamine results in decreased expression of FDFT1 mRNA CTD PMID:20080153 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fem1b fem-1 homolog B increases expression EXP Ketamine results in increased expression of FEM1B mRNA CTD PMID:20080153 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression EXP Ketamine results in increased expression of FGFR3 mRNA CTD PMID:20080153 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression EXP Ketamine results in decreased expression of FGFRL1 mRNA CTD PMID:20080153 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928
JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 increases expression EXP Ketamine results in increased expression of FKBP15 mRNA CTD PMID:20080153 NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
EXP
ISO
Ketamine results in increased expression of FN1 protein
Ketamine results in increased expression of FN1 mRNA; Ketamine results in increased expression of FN1 protein
2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of FN1 protein]
CTD PMID:28331066 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fn3k fructosamine 3 kinase increases expression EXP Ketamine results in increased expression of FN3K mRNA CTD PMID:20080153 NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Ketamine inhibits the reaction [Formaldehyde results in increased expression of FOS protein] CTD PMID:17551412 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo1 forkhead box O1 decreases expression EXP Ketamine results in decreased expression of FOXO1 mRNA CTD PMID:20080153 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Frem3 FRAS1 related extracellular matrix 3 increases expression EXP Ketamine results in increased expression of FREM3 mRNA CTD PMID:20080153 NCBI chr19:27,308,469...27,366,771
Ensembl chr19:27,308,469...27,366,771
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression EXP Ketamine results in decreased expression of FUBP1 mRNA CTD PMID:20080153 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fxyd7 FXYD domain-containing ion transport regulator 7 increases expression EXP Ketamine results in increased expression of FXYD7 mRNA CTD PMID:20080153 NCBI chr 1:86,277,678...86,286,954
Ensembl chr 1:86,277,678...86,286,954
JBrowse link
G G0s2 G0/G1switch 2 decreases expression EXP Ketamine results in decreased expression of G0S2 mRNA CTD PMID:20080153 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 increases expression ISO Ketamine results in increased expression of GABRA5 mRNA; Ketamine results in increased expression of GABRA5 protein CTD PMID:21712993 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP Ketamine results in decreased expression of GABRB2 mRNA CTD PMID:20080153 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta increases expression EXP Ketamine results in increased expression of GABRD mRNA CTD PMID:20080153 NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP Ketamine results in decreased expression of GABRG2 mRNA CTD PMID:20080153 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
increases expression
decreases expression
ISO acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein]
Ketamine results in increased expression of GAD1 mRNA
CTD PMID:18063801 PMID:23660488 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 increases expression EXP Ketamine results in increased expression of GALNT16 mRNA CTD PMID:20080153 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
JBrowse link
G Galr2 galanin receptor 2 decreases expression EXP Ketamine results in decreased expression of GALR2 mRNA CTD PMID:20080153 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression EXP Ketamine results in increased expression of GAPDHS mRNA CTD PMID:20080153 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640
JBrowse link
G Garin5a golgi associated RAB2 interactor 5A increases expression EXP Ketamine results in increased expression of GARIN5A mRNA CTD PMID:20080153 NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B decreases expression EXP Ketamine results in decreased expression of GATAD2B mRNA CTD PMID:20080153 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
JBrowse link
G Gca grancalcin decreases expression EXP Ketamine results in decreased expression of GCA mRNA CTD PMID:20080153 NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
decreases expression
EXP Ketamine results in increased expression of GCLC mRNA
Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC protein]
Ketamine results in decreased expression of GCLC mRNA; Ketamine results in decreased expression of GCLC protein
CTD PMID:20080153 PMID:36305173 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 increases expression EXP Ketamine results in increased expression of GDAP1L1 mRNA CTD PMID:20080153 NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP Ketamine results in increased expression of GFAP mRNA CTD PMID:20080153 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfod2 Gfo/Idh/MocA-like oxidoreductase domain containing 2 decreases expression EXP Ketamine results in decreased expression of GFOD2 mRNA CTD PMID:20080153 NCBI chr19:33,599,689...33,647,060
Ensembl chr19:33,604,187...33,647,004
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 decreases expression EXP Ketamine results in decreased expression of GFPT2 mRNA CTD PMID:20080153 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
JBrowse link
G Ggact gamma-glutamylamine cyclotransferase increases expression EXP Ketamine results in increased expression of GGACT mRNA CTD PMID:20080153 NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455
JBrowse link
G Gjb6 gap junction protein, beta 6 increases expression EXP Ketamine results in increased expression of GJB6 mRNA CTD PMID:20080153 NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582
JBrowse link
G Glul glutamate-ammonia ligase increases expression
multiple interactions
EXP
ISO
Ketamine results in increased expression of GLUL protein
[Guanosine co-treated with Ketamine] results in increased activity of GLUL protein
CTD PMID:18504422 PMID:36878458 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gpr22 G protein-coupled receptor 22 increases expression EXP Ketamine results in increased expression of GPR22 mRNA CTD PMID:20080153 NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 increases expression EXP Ketamine results in increased expression of GPR37L1 mRNA CTD PMID:20080153 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
JBrowse link
G Gpr84 G protein-coupled receptor 84 multiple interactions
decreases expression
EXP Cannabidiol inhibits the reaction [Ketamine results in decreased expression of GPR84 mRNA] CTD PMID:31823199 NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression EXP Ketamine results in decreased expression of GPR85 mRNA CTD PMID:20080153 NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression
multiple interactions
ISO Ketamine results in decreased expression of GRIA1 protein
Ketamine inhibits the reaction [Corticosterone results in decreased expression of GRIA1 protein]; MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein]
CTD PMID:31470060 PMID:33872575 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions
decreases expression
ISO MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein] CTD PMID:31470060 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression EXP Ketamine results in increased expression of GRIK5 mRNA CTD PMID:20080153 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression EXP Ketamine results in increased expression of GRIN1 mRNA; Ketamine results in increased expression of GRIN1 protein CTD PMID:19126600 PMID:20080153 PMID:23065140 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A affects response to substance
increases expression
ISO
EXP
GRIN2A protein affects the susceptibility to Ketamine
Ketamine results in increased expression of GRIN2A mRNA
CTD PMID:15731593 PMID:20080153 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP Ketamine inhibits the reaction [remifentanil results in increased phosphorylation of GRIN2B protein] CTD PMID:20042082 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Ketamine results in increased expression of GRIN2C mRNA CTD PMID:20080153 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Grm3 glutamate metabotropic receptor 3 decreases expression EXP Ketamine results in decreased expression of GRM3 mRNA CTD PMID:20080153 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions
increases phosphorylation
EXP Ketamine results in decreased phosphorylation of GSK3B protein
Chir 99021 inhibits the reaction [Ketamine results in increased phosphorylation of GSK3B protein]
CTD PMID:17952604 PMID:36334642 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsto2 glutathione S-transferase omega 2 increases expression EXP Ketamine results in increased expression of GSTO2 mRNA CTD PMID:20080153 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 decreases expression EXP Ketamine results in decreased expression of GTF2H3 mRNA CTD PMID:20080153 NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497
JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 increases expression EXP Ketamine results in increased expression of GTF2IRD1 mRNA CTD PMID:20080153 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 decreases expression EXP Ketamine results in decreased expression of GUCY1B1 mRNA CTD PMID:20080153 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Habp4 hyaluronan binding protein 4 increases expression EXP Ketamine results in increased expression of HABP4 mRNA CTD PMID:20080153 NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression EXP Ketamine results in decreased expression of HACD3 mRNA CTD PMID:20080153 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression EXP Ketamine results in increased expression of HAP1 mRNA CTD PMID:20080153 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Haus8 HAUS augmin-like complex, subunit 8 decreases expression EXP Ketamine results in decreased expression of HAUS8 mRNA CTD PMID:20080153 NCBI chr16:17,930,819...17,945,254
Ensembl chr16:17,930,820...17,945,237
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO [Ketamine co-treated with Xylazine] results in increased secretion of HAVCR1 protein CTD PMID:30538007 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Ketamine results in decreased expression of HBB-B1 mRNA CTD PMID:20080153 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hecw1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 decreases expression EXP Ketamine results in decreased expression of HECW1 mRNA CTD PMID:20080153 NCBI chr17:50,671,239...51,084,536
Ensembl chr17:50,670,954...51,080,720
JBrowse link
G Hes5 hes family bHLH transcription factor 5 decreases expression EXP Ketamine results in decreased expression of HES5 mRNA CTD PMID:20080153 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP Ketamine results in decreased expression of HES6 mRNA CTD PMID:20080153 NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases expression EXP Ketamine results in decreased expression of HIBCH mRNA CTD PMID:20080153 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
JBrowse link
G Hmgcll1 3-hydroxy-3-methylglutaryl-CoA lyase like 1 decreases expression EXP Ketamine results in decreased expression of HMGCLL1 mRNA CTD PMID:20080153 NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP Ketamine results in decreased expression of HMGCR mRNA CTD PMID:20080153 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Ketamine results in increased expression of HMGCS2 mRNA CTD PMID:20080153 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 decreases expression EXP Ketamine results in decreased expression of HMGN1 mRNA CTD PMID:20080153 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 increases expression EXP Ketamine results in increased expression of HMGN3 mRNA CTD PMID:20080153 NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
EXP Ketamine results in decreased expression of HMOX1 mRNA; Ketamine results in decreased expression of HMOX1 protein
Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 protein]
CTD PMID:36305173 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hmox2 heme oxygenase 2 increases expression EXP Ketamine results in increased expression of HMOX2 mRNA CTD PMID:20080153 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Ketamine results in increased expression of HNRNPA2B1 protein CTD PMID:18504422 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 decreases expression EXP Ketamine results in decreased expression of HNRNPH3 mRNA CTD PMID:20080153 NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750
JBrowse link
G Hopx HOP homeobox increases expression EXP Ketamine results in increased expression of HOPX mRNA CTD PMID:20080153 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909
JBrowse link
G Hpca hippocalcin increases expression EXP Ketamine results in increased expression of HPCA mRNA CTD PMID:20080153 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like decreases expression EXP Ketamine results in decreased expression of HPDL mRNA CTD PMID:20080153 NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression EXP Ketamine results in decreased expression of HPGD mRNA CTD PMID:20080153 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of HRAS protein] CTD PMID:19540866 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hrh3 histamine receptor H3 increases expression EXP Ketamine results in increased expression of HRH3 mRNA CTD PMID:20080153 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression EXP Ketamine results in increased expression of HRK mRNA CTD PMID:20080153 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 decreases expression EXP Ketamine results in decreased expression of HS3ST5 mRNA CTD PMID:20080153 NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Ketamine results in increased expression of HSD11B1 mRNA CTD PMID:20080153 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression EXP Ketamine results in decreased expression of HSD17B4 mRNA CTD PMID:20080153 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP Ketamine results in increased expression of HSPA2 mRNA CTD PMID:20080153 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
increases expression
multiple interactions
affects expression
EXP
ISO
Ketamine results in decreased expression of HSPA5 mRNA
Ketamine results in increased expression of HSPA5 protein
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]
Ketamine affects the expression of HSPA5 mRNA
CTD PMID:20080153 PMID:35728656 PMID:36907275 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression EXP Ketamine results in increased expression of HTRA1 mRNA CTD PMID:20080153 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icam5 intercellular adhesion molecule 5 increases expression EXP Ketamine results in increased expression of ICAM5 mRNA CTD PMID:20080153 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression EXP Ketamine results in decreased expression of IDH1 mRNA CTD PMID:20080153 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP Ketamine results in decreased expression of IDI1 mRNA CTD PMID:20080153 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression EXP Ketamine results in increased expression of IFI27 mRNA; Ketamine results in increased expression of IFI27L1 mRNA CTD PMID:20080153 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifitm10 interferon induced transmembrane protein 10 increases expression EXP Ketamine results in increased expression of IFITM10 mRNA CTD PMID:20080153 NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression EXP Ketamine results in increased expression of IFNGR1 mRNA CTD PMID:20080153 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Ifngr2 interferon gamma receptor 2 increases expression EXP Ketamine results in increased expression of IFNGR2 mRNA CTD PMID:20080153 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP Ketamine results in increased expression of IGFBP1 mRNA CTD PMID:20080153 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression EXP Ketamine results in increased expression of IGFBP3 mRNA CTD PMID:20080153 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Igfbpl1 insulin-like growth factor binding protein-like 1 decreases expression EXP Ketamine results in decreased expression of IGFBPL1 mRNA CTD PMID:20080153 NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833
JBrowse link
G Igsf9 immunoglobulin superfamily, member 9 decreases expression EXP Ketamine results in decreased expression of IGSF9 mRNA CTD PMID:20080153 NCBI chr13:84,948,643...84,965,616
Ensembl chr13:84,948,619...84,965,607
JBrowse link
G Ikbip IKBKB interacting protein decreases expression EXP Ketamine results in decreased expression of IKBIP mRNA CTD PMID:20080153 NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162
JBrowse link
G Il12a interleukin 12A increases expression EXP Ketamine results in increased expression of IL12A mRNA CTD PMID:20080153 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
multiple interactions
EXP
ISO
Ketamine results in increased expression of IL1B mRNA; Ketamine results in increased expression of IL1B protein
Ketamine results in increased secretion of IL1B protein
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]
Ozone inhibits the reaction [Ketamine results in increased expression of IL1B mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL1B protein]
CTD PMID:15207037 PMID:15207038 PMID:19540866 PMID:22245128 PMID:33536391 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
affects response to substance
ISO
EXP
Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
TRPV4 protein affects the reaction [Ketamine results in increased expression of IL6 protein]
[Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Ketamine results in increased expression of IL6 protein]
Ketamine results in increased expression of IL6 mRNA; Ketamine results in increased expression of IL6 protein
IL6 affects the susceptibility to Ketamine
CTD PMID:15207037 PMID:15207038 PMID:15720977 PMID:19091984 PMID:19540866 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression EXP Ketamine results in increased expression of INA protein CTD PMID:18504422 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Ing2 inhibitor of growth family, member 2 increases expression EXP Ketamine results in increased expression of ING2 mRNA CTD PMID:20080153 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP Ketamine results in decreased expression of INHBA mRNA CTD PMID:20080153 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Ino80c INO80 complex subunit C increases expression EXP Ketamine results in increased expression of INO80C mRNA CTD PMID:20080153 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression EXP Ketamine results in increased expression of INPP5D mRNA CTD PMID:20080153 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F decreases expression EXP Ketamine results in decreased expression of INPP5F mRNA CTD PMID:20080153 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
JBrowse link
G Ints3 integrator complex subunit 3 decreases expression EXP Ketamine results in decreased expression of INTS3 mRNA CTD PMID:20080153 NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 decreases expression EXP Ketamine results in decreased expression of ISYNA1 mRNA CTD PMID:20080153 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP Ketamine results in increased expression of ITIH3 mRNA CTD PMID:20080153 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itm2c integral membrane protein 2C increases expression EXP Ketamine results in increased expression of ITM2C mRNA CTD PMID:20080153 NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A increases expression EXP Ketamine results in increased expression of ITPKA mRNA CTD PMID:20080153 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600
JBrowse link
G Ivns1abp influenza virus NS1A binding protein decreases expression EXP Ketamine results in decreased expression of IVNS1ABP mRNA CTD PMID:20080153 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Jade3 jade family PHD finger 3 decreases expression EXP Ketamine results in decreased expression of JADE3 mRNA CTD PMID:20080153 NCBI chr  X:1,668,873...1,848,781
Ensembl chr  X:1,669,930...1,845,138
JBrowse link
G Jag2 jagged canonical Notch ligand 2 decreases expression EXP Ketamine results in decreased expression of JAG2 mRNA CTD PMID:20080153 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
JBrowse link
G Jak2 Janus kinase 2 decreases expression EXP Ketamine results in decreased expression of JAK2 mRNA CTD PMID:20080153 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jmjd1c jumonji domain containing 1C decreases expression EXP Ketamine results in decreased expression of JMJD1C mRNA CTD PMID:20080153 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Ketamine results in increased expression of JUN mRNA CTD PMID:20080153 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kazald1 Kazal-type serine peptidase inhibitor domain 1 increases expression EXP Ketamine results in increased expression of KAZALD1 mRNA CTD PMID:20080153 NCBI chr 1:243,939,596...243,943,060
Ensembl chr 1:243,939,647...243,943,059
JBrowse link
G Kazn kazrin, periplakin interacting protein increases expression EXP Ketamine results in increased expression of KAZN mRNA CTD PMID:20080153 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 decreases expression EXP Ketamine results in decreased expression of KCNC2 mRNA CTD PMID:20080153 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 decreases expression EXP Ketamine results in decreased expression of KCNG1 mRNA CTD PMID:20080153 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 increases expression EXP Ketamine results in increased expression of KCNIP2 mRNA CTD PMID:20080153 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
JBrowse link
G Kcnj14 potassium inwardly-rectifying channel, subfamily J, member 14 decreases expression EXP Ketamine results in decreased expression of KCNJ14 mRNA CTD PMID:20080153 NCBI chr 1:96,293,159...96,300,810
Ensembl chr 1:96,293,435...96,495,459
JBrowse link
G Kcns3 potassium voltage-gated channel, modifier subfamily S, member 3 decreases expression EXP Ketamine results in decreased expression of KCNS3 mRNA CTD PMID:20080153 NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125
JBrowse link
G Kiaa0319 KIAA0319 homolog decreases expression EXP Ketamine results in decreased expression of KIAA0319 mRNA CTD PMID:20080153 NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
JBrowse link
G Kif11 kinesin family member 11 decreases expression EXP Ketamine results in decreased expression of KIF11 mRNA CTD PMID:20080153 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP Ketamine results in decreased expression of KIF20A mRNA CTD PMID:20080153 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Klf15 KLF transcription factor 15 increases expression EXP Ketamine results in increased expression of KLF15 mRNA CTD PMID:20080153 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf6 KLF transcription factor 6 decreases expression EXP Ketamine results in decreased expression of KLF6 mRNA CTD PMID:20080153 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klf9 KLF transcription factor 9 increases expression EXP Ketamine results in increased expression of KLF9 mRNA CTD PMID:20080153 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Klhdc1 kelch domain containing 1 decreases expression EXP Ketamine results in decreased expression of KLHDC1 mRNA CTD PMID:20080153 NCBI chr 6:87,670,182...87,765,431
Ensembl chr 6:87,712,772...87,765,424
JBrowse link
G Klhdc9 kelch domain containing 9 increases expression EXP Ketamine results in increased expression of KLHDC9 mRNA CTD PMID:20080153 NCBI chr13:83,790,390...83,794,080
Ensembl chr13:83,790,269...83,793,354
JBrowse link
G Klhl24 kelch-like family member 24 decreases expression EXP Ketamine results in decreased expression of KLHL24 mRNA CTD PMID:20080153 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Klhl7 kelch-like family member 7 decreases expression EXP Ketamine results in decreased expression of KLHL7 mRNA CTD PMID:20080153 NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541
JBrowse link
G Klhl8 kelch-like family member 8 decreases expression EXP Ketamine results in decreased expression of KLHL8 mRNA CTD PMID:20080153 NCBI chr14:5,807,795...5,853,325
Ensembl chr14:5,807,907...5,853,294
JBrowse link
G Klhl9 kelch-like family member 9 decreases expression EXP Ketamine results in decreased expression of KLHL9 mRNA CTD PMID:20080153 NCBI chr 5:103,333,747...103,337,931 JBrowse link
G Kmt5a lysine methyltransferase 5A decreases expression EXP Ketamine results in decreased expression of KMT5A mRNA CTD PMID:20080153 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711
JBrowse link
G Kng1 kininogen 1 multiple interactions ISO Ketamine inhibits the reaction [KNG1 protein results in increased expression of OCLN protein] CTD PMID:27638051 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein decreases expression EXP Ketamine results in decreased expression of KNSTRN mRNA CTD PMID:20080153 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression EXP Ketamine results in decreased expression of KPNA2 mRNA CTD PMID:20080153 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression EXP Ketamine results in decreased expression of KPNB1 mRNA CTD PMID:20080153 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Ktn1 kinectin 1 decreases expression EXP Ketamine results in decreased expression of KTN1 mRNA CTD PMID:20080153 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression EXP Ketamine results in decreased expression of LAMB1 mRNA CTD PMID:20080153 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamp5 lysosomal-associated membrane protein family, member 5 increases expression EXP Ketamine results in increased expression of LAMP5 mRNA CTD PMID:20080153 NCBI chr 3:123,372,462...123,384,973
Ensembl chr 3:123,372,462...123,384,952
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta increases expression EXP Ketamine results in increased expression of LAPTM4B mRNA CTD PMID:20080153 NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 increases expression EXP Ketamine results in increased expression of LAPTM5 mRNA CTD PMID:20080153 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides binds to LBP protein] CTD PMID:19540866 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO [Ketamine co-treated with Xylazine] results in decreased secretion of LCN2 protein CTD PMID:30538007 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression EXP Ketamine results in decreased expression of LDHB protein CTD PMID:18504422 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Leng8 leukocyte receptor cluster member 8 decreases expression EXP Ketamine results in decreased expression of LENG8 mRNA CTD PMID:20080153 NCBI chr 1:70,040,785...70,052,662
Ensembl chr 1:70,040,785...70,052,488
JBrowse link
G Lep leptin multiple interactions
decreases expression
ISO LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEP protein] CTD PMID:36907275 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions
decreases expression
ISO lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEPR protein] CTD PMID:36907275 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals3bp galectin 3 binding protein increases expression EXP Ketamine results in increased expression of LGALS3BP mRNA CTD PMID:20080153 NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression EXP Ketamine results in increased expression of LGI4 mRNA CTD PMID:20080153 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Lin7b lin-7 homolog B, crumbs cell polarity complex component increases expression EXP Ketamine results in increased expression of LIN7B mRNA CTD PMID:20080153 NCBI chr 1:95,846,888...95,849,628
Ensembl chr 1:95,846,243...95,849,977
JBrowse link
G Lix1l limb and CNS expressed 1 like decreases expression EXP Ketamine results in decreased expression of LIX1L mRNA CTD PMID:20080153 NCBI chr 2:184,136,018...184,161,918
Ensembl chr 2:184,136,038...184,161,916
JBrowse link
G Lmbr1 limb development membrane protein 1 increases expression EXP Ketamine results in increased expression of LMBR1 mRNA CTD PMID:20080153 NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Ketamine results in increased expression of LMCD1 mRNA CTD PMID:20080153 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 increases expression EXP Ketamine results in increased expression of LRPAP1 mRNA CTD PMID:20080153 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link
G Lrrc42 leucine rich repeat containing 42 decreases expression EXP Ketamine results in decreased expression of LRRC42 mRNA CTD PMID:20080153 NCBI chr 5:122,014,678...122,035,792
Ensembl chr 5:122,014,678...122,035,829
JBrowse link
G Lrrc55 leucine rich repeat containing 55 decreases expression EXP Ketamine results in decreased expression of LRRC55 mRNA CTD PMID:20080153 NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639
JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated decreases expression EXP Ketamine results in decreased expression of LSM10 mRNA CTD PMID:20080153 NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505
JBrowse link
G Luc7l LUC7-like decreases expression EXP Ketamine results in decreased expression of LUC7L mRNA CTD PMID:20080153 NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 decreases expression EXP Ketamine results in decreased expression of LYPD3 mRNA CTD PMID:20080153 NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP Ketamine results in increased expression of MAL mRNA CTD PMID:20080153 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 increases expression EXP Ketamine results in increased expression of MAN2B1 mRNA CTD PMID:20080153 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor decreases expression EXP
ISO
Ketamine results in decreased expression of MANF mRNA CTD PMID:20080153 PMID:35728656 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map1b microtubule-associated protein 1B decreases expression EXP Ketamine results in decreased expression of MAP1B mRNA CTD PMID:20080153 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:19540866 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:19540866 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map6 microtubule-associated protein 6 increases expression EXP Ketamine results in increased expression of MAP6 mRNA CTD PMID:20080153 NCBI chr 1:153,568,020...153,634,415
Ensembl chr 1:153,568,368...153,634,414
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:19540866 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:19540866 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 decreases expression EXP Ketamine results in decreased expression of MAPK7 mRNA CTD PMID:20080153 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mapt microtubule-associated protein tau increases phosphorylation
multiple interactions
ISO Ketamine results in increased phosphorylation of MAPT protein
MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein]; MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein]
CTD PMID:20093173 PMID:31470060 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marf1 meiosis regulator and mRNA stability factor 1 decreases expression EXP Ketamine results in decreased expression of MARF1 mRNA CTD PMID:20080153 NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Ketamine results in decreased expression of MAS1 mRNA CTD PMID:20080153 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression EXP Ketamine results in increased expression of MATK mRNA CTD PMID:20080153 NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022
JBrowse link
G Mavs mitochondrial antiviral signaling protein decreases expression EXP Ketamine results in decreased expression of MAVS mRNA CTD PMID:20080153 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mbp myelin basic protein increases expression EXP Ketamine results in increased expression of MBP mRNA CTD PMID:20080153 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression EXP Ketamine results in decreased expression of MCM3 mRNA CTD PMID:20080153 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcu mitochondrial calcium uniporter decreases expression EXP Ketamine results in decreased expression of MCU mRNA CTD PMID:20080153 NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110
JBrowse link
G Mettl16 methyltransferase 16, RNA N6-adenosine decreases expression EXP Ketamine results in decreased expression of METTL16 mRNA CTD PMID:20080153 NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061
JBrowse link
G Mettl25b methyltransferase like 25B increases expression EXP Ketamine results in increased expression of METTL25B mRNA CTD PMID:20080153 NCBI chr 2:173,388,625...173,397,279
Ensembl chr 2:173,388,625...173,397,279
JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit decreases expression EXP Ketamine results in decreased expression of METTL3 mRNA CTD PMID:20080153 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid increases expression EXP Ketamine results in increased expression of MFSD2A mRNA CTD PMID:20080153 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression EXP Ketamine results in increased expression of MGST2 mRNA CTD PMID:20080153 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mgst3l1 microsomal glutathione S-transferase 3 like 1 increases expression EXP Ketamine results in increased expression of MGST3L1 mRNA CTD PMID:20080153 NCBI chr14:19,525,509...19,526,128
Ensembl chr14:19,525,558...19,526,016
JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 increases expression EXP Ketamine results in increased expression of MIB1 mRNA CTD PMID:20080153 NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 decreases expression EXP Ketamine results in decreased expression of MICAL1 mRNA CTD PMID:20080153 NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089
JBrowse link
G Mif4gd MIF4G domain containing increases expression EXP Ketamine results in increased expression of MIF4GD mRNA CTD PMID:20080153 NCBI chr10:100,847,168...100,852,166 JBrowse link
G Mis12 MIS12 kinetochore complex component decreases expression EXP Ketamine results in decreased expression of MIS12 mRNA CTD PMID:20080153 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Mis18a MIS18 kinetochore protein A decreases expression EXP Ketamine results in decreased expression of MIS18A mRNA CTD PMID:20080153 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Ketamine results in increased expression of MKI67 protein CTD PMID:19919587 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mkks MKKS centrosomal shuttling protein decreases expression EXP Ketamine results in decreased expression of MKKS mRNA CTD PMID:20080153 NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162
JBrowse link
G Mllt3 MLLT3, super elongation complex subunit decreases expression EXP Ketamine results in decreased expression of MLLT3 mRNA CTD PMID:20080153 NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361
JBrowse link
G Mmd2 monocyte to macrophage differentiation-associated 2 increases expression EXP Ketamine results in increased expression of MMD2 mRNA CTD PMID:20080153 NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP Ketamine results in decreased expression of MMP14 mRNA CTD PMID:20080153 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mog myelin oligodendrocyte glycoprotein increases expression EXP Ketamine results in increased expression of MOG mRNA CTD PMID:20080153 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Mon1a MON1 homolog A, secretory trafficking associated decreases expression EXP Ketamine results in decreased expression of MON1A mRNA CTD PMID:20080153 NCBI chr 8:108,574,272...108,593,163
Ensembl chr 8:108,574,388...108,593,156
JBrowse link
G Morn2 MORN repeat containing 2 increases expression EXP Ketamine results in increased expression of MORN2 mRNA CTD PMID:20080153 NCBI chr 6:14,718,799...14,725,281 JBrowse link
G Mras muscle RAS oncogene homolog increases expression EXP Ketamine results in increased expression of MRAS mRNA CTD PMID:20080153 NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 decreases expression EXP Ketamine results in decreased expression of MRPL18 mRNA CTD PMID:20080153 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
JBrowse link
G Mrpl50 mitochondrial ribosomal protein L50 decreases expression EXP Ketamine results in decreased expression of MRPL50 mRNA CTD PMID:20080153 NCBI chr 5:63,867,437...63,872,591 JBrowse link
G Mrps15 mitochondrial ribosomal protein S15 increases expression EXP Ketamine results in increased expression of MRPS15 mRNA CTD PMID:20080153 NCBI chr 5:138,321,610...138,332,205
Ensembl chr 5:138,321,593...138,332,205
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A increases expression EXP Ketamine results in increased expression of MS4A6A mRNA CTD PMID:20080153 NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
JBrowse link
G Msantd3 Myb/SANT DNA binding domain containing 3 increases expression EXP Ketamine results in increased expression of MSANTD3 mRNA CTD PMID:20080153 NCBI chr 5:62,866,022...62,892,444
Ensembl chr 5:62,866,022...62,888,859
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression EXP Ketamine results in decreased expression of MSMO1 mRNA CTD PMID:20080153 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Ketamine results in increased expression of MT1A mRNA CTD PMID:20080153 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mtcl3 MTCL family member 3 decreases expression EXP Ketamine results in decreased expression of MTCL3 mRNA CTD PMID:20080153 NCBI chr 1:28,629,036...28,701,416
Ensembl chr 1:28,620,293...28,701,796
JBrowse link
G Mterf2 mitochondrial transcription termination factor 2 decreases expression EXP Ketamine results in decreased expression of MTERF2 mRNA CTD PMID:20080153 NCBI chr 7:18,598,202...18,608,278
Ensembl chr 7:18,598,103...18,620,684
JBrowse link
G Mtg2 mitochondrial ribosome-associated GTPase 2 decreases expression EXP Ketamine results in decreased expression of MTG2 mRNA CTD PMID:20080153 NCBI chr 3:167,165,542...167,181,358
Ensembl chr 3:167,165,982...167,181,358
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Ketamine results in decreased expression of MYC mRNA CTD PMID:20080153 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression EXP Ketamine results in decreased expression of MYCN mRNA CTD PMID:20080153 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Myo19 myosin XIX decreases expression EXP Ketamine results in decreased expression of MYO19 mRNA CTD PMID:20080153 NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450
JBrowse link
G Naa35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit decreases expression EXP Ketamine results in decreased expression of MAK10 mRNA CTD PMID:20080153 NCBI chr17:5,034,360...5,086,456
Ensembl chr17:5,034,356...5,086,386
JBrowse link
G Nab1 Ngfi-A binding protein 1 decreases expression EXP Ketamine results in decreased expression of NAB1 mRNA CTD PMID:20080153 NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098
JBrowse link
G Nabp1 nucleic acid binding protein 1 decreases expression EXP Ketamine results in decreased expression of NABP1 mRNA CTD PMID:20080153 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
JBrowse link
G Nav3 neuron navigator 3 decreases expression EXP Ketamine results in decreased expression of NAV3 mRNA CTD PMID:20080153 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
JBrowse link
G Ncdn neurochondrin increases expression EXP Ketamine results in increased expression of NCDN mRNA CTD PMID:20080153 NCBI chr 5:139,037,807...139,047,645
Ensembl chr 5:139,037,819...139,047,568
JBrowse link
G Nckap1l NCK associated protein 1 like decreases expression
multiple interactions
EXP Ketamine results in decreased expression of NCKAP1L mRNA
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of NCKAP1L mRNA]
CTD PMID:31823199 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Ndrg2 NDRG family member 2 increases expression EXP Ketamine results in increased expression of NDRG2 mRNA CTD PMID:20080153 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression EXP Ketamine results in decreased expression of NDUFS1 protein CTD PMID:18504422 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression EXP Ketamine results in decreased expression of NECTIN3 mRNA CTD PMID:20080153 NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519
JBrowse link
G Nefl neurofilament light chain decreases expression
increases expression
EXP Ketamine results in decreased expression of NEFL protein
Ketamine results in increased expression of NEFL mRNA
CTD PMID:18504422 PMID:20080153 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nes nestin decreases expression EXP Ketamine results in decreased expression of NES mRNA CTD PMID:20080153 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Neurod6 neuronal differentiation 6 decreases expression EXP Ketamine results in decreased expression of NEUROD6 mRNA CTD PMID:20080153 NCBI chr 4:84,846,659...84,849,905
Ensembl chr 4:84,846,231...84,849,999
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions
EXP Ketamine results in decreased expression of NFE2L2 mRNA; Ketamine results in decreased expression of NFE2L2 protein; Ketamine results in decreased expression of NFE2L2 protein modified form
Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein modified form]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein]
CTD PMID:36305173 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfe2l3 NFE2 like bZIP transcription factor 3 decreases expression EXP Ketamine results in decreased expression of NFE2L3 mRNA CTD PMID:20080153 NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression EXP Ketamine results in decreased expression of NFIL3 mRNA CTD PMID:20080153 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
increases phosphorylation
multiple interactions
EXP Ketamine results in increased expression of NFKBIA mRNA
Ketamine results in increased phosphorylation of NFKBIA protein
TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of NFKBIA protein]
CTD PMID:20080153 PMID:33536391 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Ketamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA] CTD PMID:8635431 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nif3l1 NGG1 interacting factor 3 like 1 decreases expression EXP Ketamine results in decreased expression of NIF3L1 mRNA CTD PMID:20080153 NCBI chr 9:59,980,101...60,001,490
Ensembl chr 9:59,979,799...60,000,131
JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 increases expression EXP Ketamine results in increased expression of NKIRAS1 mRNA CTD PMID:20080153 NCBI chr15:7,493,531...7,503,758
Ensembl chr15:7,493,531...7,503,854
JBrowse link
G Nkx6-2 NK6 homeobox 2 increases expression EXP Ketamine results in increased expression of NKX6-2 mRNA CTD PMID:20080153 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
JBrowse link
G Nln neurolysin decreases expression EXP Ketamine results in decreased expression of NLN mRNA CTD PMID:20080153 NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914
JBrowse link
G Nmb neuromedin B increases expression EXP Ketamine results in increased expression of NMB mRNA CTD PMID:20080153 NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 decreases expression EXP Ketamine results in decreased expression of NME6 mRNA CTD PMID:20080153 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression EXP Ketamine results in decreased expression of NNT mRNA CTD PMID:20080153 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
JBrowse link
G Nol4 nucleolar protein 4 decreases expression EXP Ketamine results in decreased expression of NOL4 mRNA CTD PMID:20080153 NCBI chr18:13,932,499...14,294,873
Ensembl chr18:13,932,510...14,296,286
JBrowse link
G Nova2 NOVA alternative splicing regulator 2 decreases expression EXP Ketamine results in decreased expression of NOVA2 mRNA CTD PMID:20080153 NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021
JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 decreases expression EXP Ketamine results in decreased expression of NPM3 mRNA CTD PMID:20080153 NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591
JBrowse link
G Nppc natriuretic peptide C decreases expression EXP Ketamine results in decreased expression of NPPC mRNA CTD PMID:20080153 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Npy neuropeptide Y increases response to substance ISO NPY protein results in increased susceptibility to Ketamine CTD PMID:11454027 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Npy1r neuropeptide Y receptor Y1 decreases expression EXP Ketamine results in decreased expression of NPY1R mRNA CTD PMID:20080153 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
EXP Ketamine results in decreased expression of NQO1 mRNA; Ketamine results in decreased expression of NQO1 protein
Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 protein]
CTD PMID:36305173 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Ketamine results in increased expression of NR1D1 mRNA CTD PMID:20080153 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP Ketamine results in decreased expression of NR4A2 mRNA CTD PMID:20080153 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression EXP Ketamine results in decreased expression of NR4A3 mRNA CTD PMID:20080153 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nradd neurotrophin receptor associated death domain decreases expression EXP Ketamine results in decreased expression of NRADD mRNA CTD PMID:20080153 NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:110,599,667...110,603,149
JBrowse link
G Nrde2 NRDE-2, necessary for RNA interference, domain containing increases expression EXP Ketamine results in increased expression of NRDE2 mRNA CTD PMID:20080153 NCBI chr 6:119,405,103...119,446,861
Ensembl chr 6:119,404,334...119,448,915
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Ketamine results in decreased expression of NREP mRNA CTD PMID:20080153 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Nrg1 neuregulin 1 decreases expression ISO Ketamine results in decreased expression of NRG1 mRNA CTD PMID:20000043 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrgn neurogranin increases expression EXP Ketamine results in increased expression of NRGN mRNA CTD PMID:20080153 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516
JBrowse link
G Nrip3 nuclear receptor interacting protein 3 decreases expression EXP Ketamine results in decreased expression of NRIP3 mRNA CTD PMID:20080153 NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression EXP Ketamine results in increased expression of NSF mRNA CTD PMID:20080153 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase decreases expression EXP Ketamine results in decreased expression of NSMCE2 mRNA CTD PMID:20080153 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression EXP Ketamine results in increased expression of NT5C2 mRNA CTD PMID:20080153 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913
JBrowse link
G Ntf3 neurotrophin 3 decreases expression EXP Ketamine results in decreased expression of NTF3 mRNA CTD PMID:20080153 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 increases expression EXP Ketamine results in increased expression of NTRK1 mRNA CTD PMID:20080153 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP
ISO
Ketamine inhibits the reaction [Pilocarpine results in increased expression of NTRK2 mRNA]
Ketamine inhibits the reaction [NTRK2 protein binds to AP2M1 protein]
CTD PMID:8635431 PMID:31631060 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Nudt6 nudix hydrolase 6 increases expression EXP Ketamine results in increased expression of NUDT6 mRNA CTD PMID:20080153 NCBI chr 2:120,289,908...120,306,197
Ensembl chr 2:120,290,847...120,306,230
JBrowse link
G Nup205 nucleoporin 205 decreases expression EXP Ketamine results in decreased expression of NUP205 mRNA CTD PMID:20080153 NCBI chr 4:63,854,934...63,920,852
Ensembl chr 4:63,854,783...63,920,844
JBrowse link
G Nup35 nucleoporin 35 decreases expression EXP Ketamine results in decreased expression of NUP35 mRNA CTD PMID:20080153 NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130
JBrowse link
G Nup42 nucleoporin 42 increases expression EXP Ketamine results in increased expression of NUP42 mRNA CTD PMID:20080153 NCBI chr 4:10,985,554...11,002,591
Ensembl chr 4:10,985,554...11,002,591
JBrowse link
G Nup58 nucleoporin 58 decreases expression EXP Ketamine results in decreased expression of NUP58 mRNA CTD PMID:20080153 NCBI chr15:34,358,170...34,407,160
Ensembl chr15:34,358,277...34,407,060
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression EXP Ketamine results in decreased expression of NUSAP1 mRNA CTD PMID:20080153 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Ocln occludin multiple interactions ISO Ketamine inhibits the reaction [KNG1 protein results in increased expression of OCLN protein] CTD PMID:27638051 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Oplah 5-oxoprolinase (ATP-hydrolysing) increases expression EXP Ketamine results in increased expression of OPLAH mRNA CTD PMID:20080153 NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297
JBrowse link
G Orc4 origin recognition complex, subunit 4 increases expression EXP Ketamine results in increased expression of ORC4 mRNA CTD PMID:20080153 NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 increases expression EXP Ketamine results in increased expression of ORMDL3 mRNA CTD PMID:20080153 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 decreases expression EXP Ketamine results in decreased expression of OXSR1 mRNA CTD PMID:20080153 NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
JBrowse link
G P2rx6 purinergic receptor P2X 6 increases expression EXP Ketamine results in increased expression of P2RX6 mRNA CTD PMID:20080153 NCBI chr11:83,439,922...83,450,449
Ensembl chr11:83,439,924...83,450,481
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression EXP Ketamine results in decreased expression of P4HA1 mRNA CTD PMID:20080153 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4htm prolyl 4-hydroxylase, transmembrane increases expression EXP Ketamine results in increased expression of P4HTM mRNA CTD PMID:20080153 NCBI chr 8:109,274,629...109,292,802
Ensembl chr 8:109,274,626...109,292,473
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 decreases expression EXP Ketamine results in decreased expression of PAK5 mRNA CTD PMID:20080153 NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930
JBrowse link
G Pank1 pantothenate kinase 1 decreases expression EXP Ketamine results in decreased expression of PANK1 mRNA CTD PMID:20080153 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Papola poly (A) polymerase alpha decreases expression EXP Ketamine results in decreased expression of PAPOLA mRNA CTD PMID:20080153 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Pard6g par-6 family cell polarity regulator gamma decreases expression EXP Ketamine results in decreased expression of PARD6G mRNA CTD PMID:20080153 NCBI chr18:73,497,992...73,565,048
Ensembl chr18:73,498,021...73,565,029
JBrowse link
G Pbk PDZ binding kinase decreases expression EXP Ketamine results in decreased expression of PBK mRNA CTD PMID:20080153 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pbx3 PBX homeobox 3 decreases expression EXP Ketamine results in decreased expression of PBX3 mRNA CTD PMID:20080153 NCBI chr 3:17,488,691...17,682,412
Ensembl chr 3:17,488,693...17,682,791
JBrowse link
G Pcgf6 polycomb group ring finger 6 decreases expression EXP Ketamine results in decreased expression of PCGF6 mRNA CTD PMID:20080153 NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression EXP Ketamine results in decreased expression of PCLAF mRNA CTD PMID:20080153 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 increases expression EXP Ketamine results in increased expression of PCSK2 mRNA CTD PMID:20080153 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Pde12 phosphodiesterase 12 increases expression EXP Ketamine results in increased expression of PDE12 mRNA CTD PMID:20080153 NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887
JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 decreases expression EXP Ketamine results in decreased expression of PDIA2 mRNA CTD PMID:20080153 NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression EXP Ketamine results in decreased expression of PDIA4 mRNA CTD PMID:20080153 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 decreases expression EXP Ketamine results in decreased expression of PDIA5 mRNA CTD PMID:20080153 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 decreases expression EXP Ketamine results in decreased expression of PDIA6 mRNA CTD PMID:20080153 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pdik1l PDLIM1 interacting kinase 1 like decreases expression EXP Ketamine results in decreased expression of PDIK1L mRNA CTD PMID:20080153 NCBI chr 5:146,495,115...146,507,363
Ensembl chr 5:146,495,115...146,506,835
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP Ketamine results in increased expression of PDK2 mRNA CTD PMID:20080153 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
JBrowse link
G Pdlim7 PDZ and LIM domain 7 decreases expression EXP Ketamine results in decreased expression of PDLIM7 mRNA CTD PMID:20080153 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811
JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 decreases expression EXP Ketamine results in decreased expression of PDP2 mRNA CTD PMID:20080153 NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 increases expression EXP Ketamine results in increased expression of PDRG1 mRNA CTD PMID:20080153 NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858
JBrowse link
G Pef1 penta-EF hand domain containing 1 increases expression EXP Ketamine results in increased expression of PEF1 mRNA CTD PMID:20080153 NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067
JBrowse link
G Per1 period circadian regulator 1 increases expression EXP Ketamine results in increased expression of PER1 mRNA CTD PMID:20080153 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pgpep1 pyroglutamyl-peptidase I decreases expression EXP Ketamine results in decreased expression of PGPEP1 mRNA CTD PMID:20080153 NCBI chr16:18,770,563...18,782,968
Ensembl chr16:18,771,021...18,783,478
JBrowse link
G Phactr3 phosphatase and actin regulator 3 decreases expression EXP Ketamine results in decreased expression of PHACTR3 mRNA CTD PMID:20080153 NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153
JBrowse link
G Phb1 prohibitin 1 increases expression EXP Ketamine results in increased expression of PHB1 protein CTD PMID:18504422 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phf13 PHD finger protein 13 decreases expression EXP Ketamine results in decreased expression of PHF13 mRNA CTD PMID:20080153 NCBI chr 5:162,494,574...162,501,350
Ensembl chr 5:162,494,573...162,501,350
JBrowse link
G Phf14 PHD finger protein 14 decreases expression EXP Ketamine results in decreased expression of PHF14 mRNA CTD PMID:20080153 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885
JBrowse link
G Phrf1 PHD and ring finger domains 1 decreases expression EXP Ketamine results in decreased expression of PHRF1 mRNA CTD PMID:20080153 NCBI chr 1:196,333,663...196,366,901
Ensembl chr 1:196,333,903...196,366,892
JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein increases expression EXP Ketamine results in increased expression of PHYHIP mRNA CTD PMID:20080153 NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 decreases expression EXP Ketamine results in decreased expression of PIBF1 mRNA CTD PMID:20080153 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Pigl phosphatidylinositol glycan anchor biosynthesis, class L decreases expression EXP Ketamine results in decreased expression of PIGL mRNA CTD PMID:20080153 NCBI chr10:47,142,160...47,199,892
Ensembl chr10:47,141,780...47,200,145
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 decreases expression EXP Ketamine results in decreased expression of PIK3AP1 mRNA CTD PMID:20080153 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression EXP Ketamine results in increased expression of PIK3IP1 mRNA CTD PMID:20080153 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha decreases expression EXP Ketamine results in decreased expression of PIP4K2A mRNA CTD PMID:20080153 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting increases expression EXP Ketamine results in increased expression of PKD1 mRNA CTD PMID:20080153 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 increases expression EXP Ketamine results in increased expression of PLAAT3 mRNA CTD PMID:20080153 NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
JBrowse link
G Plat plasminogen activator, tissue type increases expression EXP Ketamine results in increased expression of PLAT mRNA CTD PMID:20080153 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plcd4 phospholipase C, delta 4 increases expression EXP Ketamine results in increased expression of PLCD4 mRNA CTD PMID:20080153 NCBI chr 9:76,115,523...76,158,602
Ensembl chr 9:76,117,168...76,142,453
JBrowse link
G Plcl1 phospholipase C-like 1 decreases expression EXP Ketamine results in decreased expression of PLCL1 mRNA CTD PMID:20080153 NCBI chr 9:56,901,573...57,238,782
Ensembl chr 9:56,901,534...57,238,782
JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 decreases expression EXP Ketamine results in decreased expression of PLCXD3 mRNA CTD PMID:20080153 NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384
JBrowse link
G Pld4 phospholipase D family, member 4 increases expression EXP Ketamine results in increased expression of PLD4 mRNA CTD PMID:20080153 NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376
JBrowse link
G Plekhb1 pleckstrin homology domain containing B1 increases expression EXP Ketamine results in increased expression of PLEKHB1 mRNA CTD PMID:20080153 NCBI chr 1:154,998,798...155,013,094
Ensembl chr 1:154,998,800...155,016,142
JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 decreases expression EXP Ketamine results in decreased expression of PLEKHF2 mRNA CTD PMID:20080153 NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine decreases expression EXP Ketamine results in decreased expression of PLGRKT mRNA CTD PMID:20080153 NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194
JBrowse link
G Plp1 proteolipid protein 1 increases expression EXP Ketamine results in increased expression of PLP1 mRNA CTD PMID:20080153 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression EXP Ketamine results in decreased expression of PLPPR1 mRNA CTD PMID:20080153 NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
JBrowse link
G Plvap plasmalemma vesicle associated protein increases expression EXP Ketamine results in increased expression of PLVAP mRNA CTD PMID:20080153 NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301
JBrowse link
G Plxna2 plexin A2 decreases expression EXP Ketamine results in decreased expression of PLXNA2 mRNA CTD PMID:20080153 NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979
JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression EXP Ketamine results in increased expression of PMPCA mRNA CTD PMID:20080153 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844
JBrowse link
G Pnp purine nucleoside phosphorylase decreases expression EXP Ketamine results in decreased expression of PNP mRNA CTD PMID:20080153 NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP Ketamine results in increased expression of PNPLA2 mRNA CTD PMID:20080153 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
G Pofut2 protein O-fucosyltransferase 2 decreases expression EXP Ketamine results in decreased expression of POFUT2 mRNA CTD PMID:20080153 NCBI chr20:11,367,073...11,377,788
Ensembl chr20:11,367,096...11,377,743
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression EXP Ketamine results in decreased expression of POLA1 mRNA CTD PMID:20080153 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit decreases expression EXP Ketamine results in decreased expression of POLD1 mRNA CTD PMID:20080153 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit decreases expression EXP Ketamine results in decreased expression of POLE2 mRNA CTD PMID:20080153 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit decreases expression EXP Ketamine results in decreased expression of POLG mRNA CTD PMID:20080153 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
JBrowse link
G Polr2f RNA polymerase II, I and III subunit F increases expression EXP Ketamine results in increased expression of POLR2F mRNA CTD PMID:20080153 NCBI chr 7:110,712,528...110,724,234
Ensembl chr 7:110,712,572...110,724,234
JBrowse link
G Polr3f RNA polymerase III subunit F increases expression EXP Ketamine results in increased expression of POLR3F mRNA CTD PMID:20080153 NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837
JBrowse link
G Polr3h RNA polymerase III subunit H decreases expression EXP Ketamine results in decreased expression of POLR3H mRNA CTD PMID:20080153 NCBI chr 7:113,429,434...113,439,743
Ensembl chr 7:113,429,451...113,439,778
JBrowse link
G Pomt2 protein-O-mannosyltransferase 2 decreases expression EXP Ketamine results in decreased expression of POMT2 mRNA CTD PMID:20080153 NCBI chr 6:106,755,462...106,794,849
Ensembl chr 6:106,755,462...106,794,849
JBrowse link
G Potem POTE ankyrin domain family member M increases expression EXP Ketamine results in increased expression of POTEM mRNA CTD PMID:20080153 NCBI chr16:20,193,646...20,311,924
Ensembl chr16:19,949,230...19,976,541
JBrowse link
G Pou3f2 POU class 3 homeobox 2 decreases expression EXP Ketamine results in decreased expression of POU3F2 mRNA CTD PMID:20080153 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression EXP Ketamine results in decreased expression of PPP1R14B mRNA CTD PMID:20080153 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
JBrowse link
G Ppp1r18 protein phosphatase 1, regulatory subunit 18 decreases expression EXP Ketamine results in decreased expression of PPP1R18 mRNA CTD PMID:20080153 NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases expression EXP Ketamine results in increased expression of PPP1R1B mRNA CTD PMID:20080153 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Pprc1 PPARG related coactivator 1 decreases expression EXP Ketamine results in decreased expression of PPRC1 mRNA CTD PMID:20080153 NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 decreases expression EXP Ketamine results in decreased expression of PRKAG2 mRNA CTD PMID:20080153 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Prkcg protein kinase C, gamma increases expression EXP Ketamine results in increased expression of PRKCG mRNA CTD PMID:20080153 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prmt2 protein arginine methyltransferase 2 decreases expression EXP Ketamine results in decreased expression of PRMT2 mRNA CTD PMID:20080153 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
JBrowse link
G Prpf38b pre-mRNA processing factor 38B decreases expression EXP Ketamine results in decreased expression of PRPF38B mRNA CTD PMID:20080153 NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250
JBrowse link
G Prpf4b pre-mRNA processing factor 4B decreases expression EXP Ketamine results in decreased expression of PRPF4B mRNA CTD PMID:20080153 NCBI chr17:29,985,343...30,020,285
Ensembl chr17:29,985,343...30,019,625
JBrowse link
G Prr16 proline rich 16 decreases expression EXP Ketamine results in decreased expression of PRR16 mRNA CTD PMID:20080153 NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329
JBrowse link
G Psap prosaposin increases expression EXP Ketamine results in increased expression of PSAP mRNA CTD PMID:20080153 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
JBrowse link
G Ptchd1 patched domain containing 1 decreases expression EXP Ketamine results in decreased expression of PTCHD1 mRNA CTD PMID:20080153 NCBI chr  X:39,681,910...39,733,416
Ensembl chr  X:39,681,910...39,733,519
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression EXP Ketamine results in decreased expression of PTK2 mRNA CTD PMID:20080153 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptprh protein tyrosine phosphatase, receptor type, H decreases expression EXP Ketamine results in decreased expression of PTPRH mRNA CTD PMID:20080153 NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N increases expression EXP Ketamine results in increased expression of PTPRN mRNA CTD PMID:20080153 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U increases expression EXP Ketamine results in increased expression of PTPRU mRNA CTD PMID:20080153 NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768
JBrowse link
G Pvalb parvalbumin multiple interactions
decreases expression
ISO acetovanillone inhibits the reaction [Ketamine results in decreased expression of PVALB protein] CTD PMID:18063801 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Pwwp3a PWWP domain containing 3A, DNA repair factor decreases expression EXP Ketamine results in decreased expression of PWWP3A mRNA CTD PMID:20080153 NCBI chr 7:9,465,180...9,482,053
Ensembl chr 7:9,465,195...9,481,966
JBrowse link
G Pygm glycogen phosphorylase, muscle associated increases expression EXP Ketamine results in increased expression of PYGM mRNA CTD PMID:20080153 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
JBrowse link
G Rab26 RAB26, member RAS oncogene family increases expression EXP Ketamine results in increased expression of RAB26 mRNA CTD PMID:20080153 NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030
JBrowse link
G Ramp1 receptor activity modifying protein 1 increases expression EXP Ketamine results in increased expression of RAMP1 mRNA CTD PMID:20080153 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
JBrowse link
G Rasa1 RAS p21 protein activator 1 decreases expression EXP Ketamine results in decreased expression of RASA1 mRNA CTD PMID:20080153 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasd2 RASD family, member 2 increases expression EXP Ketamine results in increased expression of RASD2 mRNA CTD PMID:20080153 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 increases expression EXP Ketamine results in increased expression of RASGRF1 mRNA CTD PMID:20080153 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
JBrowse link
G Rasl11a RAS-like family 11 member A increases expression EXP Ketamine results in increased expression of RASL11A mRNA CTD PMID:20080153 NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576
JBrowse link
G Rasl11b RAS-like family 11 member B increases expression EXP Ketamine results in increased expression of RASL11B mRNA CTD PMID:20080153 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
JBrowse link
G Rassf2 Ras association domain family member 2 decreases expression EXP Ketamine results in decreased expression of RASSF2 mRNA CTD PMID:20080153 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
JBrowse link
G Rassf5 Ras association domain family member 5 increases expression EXP Ketamine results in increased expression of RASSF5 mRNA CTD PMID:20080153 NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP Ketamine results in decreased expression of RB1 mRNA CTD PMID:20080153 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbbp6 RB binding protein 6, ubiquitin ligase increases expression EXP Ketamine results in increased expression of RBBP6 mRNA CTD PMID:20080153 NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease decreases expression EXP Ketamine results in decreased expression of RBBP8 mRNA CTD PMID:20080153 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rbm12b RNA binding motif protein 12B decreases expression EXP Ketamine results in decreased expression of RBM12B mRNA CTD PMID:20080153 NCBI chr 5:25,597,405...25,610,324
Ensembl chr 5:25,590,493...25,611,245
JBrowse link
G Rbm4 RNA binding motif protein 4 decreases expression EXP Ketamine results in decreased expression of RBM4 mRNA CTD PMID:20080153 NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380
JBrowse link
G Rbm4b RNA binding motif protein 4B decreases expression EXP Ketamine results in decreased expression of RBM4B mRNA CTD PMID:20080153 NCBI chr 1:202,047,934...202,058,025
Ensembl chr 1:202,047,927...202,058,020
JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 decreases expression EXP Ketamine results in decreased expression of RBMS1 mRNA CTD PMID:20080153 NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
JBrowse link
G Recql RecQ like helicase decreases expression EXP Ketamine results in decreased expression of RECQL mRNA CTD PMID:20080153 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
JBrowse link
G Reep5 receptor accessory protein 5 decreases expression EXP Ketamine results in decreased expression of REEP5 mRNA CTD PMID:20080153 NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
EXP Ketamine results in increased phosphorylation of RELA protein
TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of RELA protein]
CTD PMID:33536391 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rem2 RRAD and GEM like GTPase 2 decreases expression EXP Ketamine results in decreased expression of REM2 mRNA CTD PMID:20080153 NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429
JBrowse link
G Ren renin increases expression ISO Ketamine results in increased expression of REN protein CTD PMID:6349867 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Resp18 regulated endocrine-specific protein 18 increases expression EXP Ketamine results in increased expression of RESP18 mRNA CTD PMID:20080153 NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
JBrowse link
G Rev1 REV1, DNA directed polymerase increases expression EXP Ketamine results in increased expression of REV1 mRNA CTD PMID:20080153 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576
JBrowse link
G Rgs19 regulator of G-protein signaling 19 decreases expression EXP Ketamine results in decreased expression of RGS19 mRNA CTD PMID:20080153 NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097
JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Ketamine results in decreased expression of RGS2 mRNA CTD PMID:20080153 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs9 regulator of G-protein signaling 9 increases expression EXP Ketamine results in increased expression of RGS9 mRNA CTD PMID:20080153 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
JBrowse link
G Rnase4 ribonuclease A family member 4 increases expression EXP Ketamine results in increased expression of RNASE4 mRNA CTD PMID:20080153 NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression EXP Ketamine results in decreased expression of RND3 mRNA CTD PMID:20080153 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rnf112 ring finger protein 112 increases expression EXP Ketamine results in increased expression of RNF112 mRNA CTD PMID:20080153 NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699
JBrowse link
G Rnf138 ring finger protein 138 decreases expression EXP Ketamine results in decreased expression of RNF138 mRNA CTD PMID:20080153 NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
JBrowse link
G Rnf31 ring finger protein 31 increases expression EXP Ketamine results in increased expression of RNF31 mRNA CTD PMID:20080153 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase increases expression EXP Ketamine results in increased expression of RNLS mRNA CTD PMID:20080153 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
JBrowse link
G Rora RAR-related orphan receptor A increases expression EXP Ketamine results in increased expression of RORA mRNA CTD PMID:20080153 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rpf2 ribosome production factor 2 homolog decreases expression EXP Ketamine results in decreased expression of RPF2 mRNA CTD PMID:20080153 NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
JBrowse link
G Rpusd3 RNA pseudouridine synthase D3 increases expression EXP Ketamine results in increased expression of RPUSD3 mRNA CTD PMID:20080153 NCBI chr 4:146,553,743...146,562,789
Ensembl chr 4:146,558,562...146,562,794
JBrowse link
G Rras2 RAS related 2 decreases expression EXP Ketamine results in decreased expression of RRAS2 mRNA CTD PMID:20080153 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP Ketamine results in decreased expression of RRM2 mRNA CTD PMID:20080153 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rrp1b ribosomal RNA processing 1B increases expression EXP Ketamine results in increased expression of RRP1B mRNA CTD PMID:20080153 NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928
JBrowse link
G Rrp7a ribosomal RNA processing 7 homolog A decreases expression EXP Ketamine results in decreased expression of RRP7A mRNA CTD PMID:20080153 NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 increases expression EXP Ketamine results in increased expression of RT1-S3 mRNA CTD PMID:20080153 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G RT1-T24-4 RT1 class I, locus T24, gene 4 increases expression EXP Ketamine results in increased expression of RT1-T24-4 mRNA CTD PMID:20080153 NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511
JBrowse link
G Rtkn rhotekin increases expression EXP Ketamine results in increased expression of RTKN mRNA CTD PMID:20080153 NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952
JBrowse link
G Rundc3a RUN domain containing 3A increases expression EXP Ketamine results in increased expression of RUNDC3A mRNA CTD PMID:20080153 NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765
JBrowse link
G Rwdd2a RWD domain containing 2A increases expression EXP Ketamine results in increased expression of RWDD2A mRNA CTD PMID:20080153 NCBI chr 8:87,536,153...87,539,301
Ensembl chr 8:87,536,176...87,539,300
JBrowse link
G Rxfp1 relaxin family peptide receptor 1 decreases expression EXP Ketamine results in decreased expression of RXFP1 mRNA CTD PMID:20080153 NCBI chr 2:164,772,270...164,893,484
Ensembl chr 2:164,774,799...164,893,412
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression EXP Ketamine results in decreased expression of RXRG mRNA CTD PMID:20080153 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G S100a11 S100 calcium binding protein A11 decreases expression EXP Ketamine results in decreased expression of S100A11 mRNA CTD PMID:20080153 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression EXP
ISO
Ketamine results in increased expression of S100A4 mRNA CTD PMID:20080153 PMID:28331066 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Ketamine results in increased expression of S100B mRNA CTD PMID:20080153 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 decreases expression EXP Ketamine results in decreased expression of S1PR2 mRNA CTD PMID:20080153 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
JBrowse link
G Samd9l1 sterile alpha motif domain containing 9 like 1 decreases expression EXP Ketamine results in decreased expression of SAMD9L mRNA CTD PMID:20080153 NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415
JBrowse link
G Satb2 SATB homeobox 2 decreases expression EXP Ketamine results in decreased expression of SATB2 mRNA CTD PMID:20080153 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
JBrowse link
G Scaper S-phase cyclin A-associated protein in the ER decreases expression EXP Ketamine results in decreased expression of SCAPER mRNA CTD PMID:20080153 NCBI chr 8:55,932,717...56,332,222
Ensembl chr 8:55,933,306...56,332,122
JBrowse link
G Scara3 scavenger receptor class A, member 3 increases expression EXP Ketamine results in increased expression of SCARA3 mRNA CTD PMID:20080153 NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894
JBrowse link
G Scarf2 scavenger receptor class F, member 2 increases expression EXP Ketamine results in increased expression of SCARF2 mRNA CTD PMID:20080153 NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP Ketamine results in increased expression of SCD1 mRNA CTD PMID:20080153 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 increases expression EXP Ketamine results in increased expression of SCN4B mRNA CTD PMID:20080153 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
JBrowse link
G Sdc1 syndecan 1 decreases expression EXP Ketamine results in decreased expression of SDC1 mRNA CTD PMID:20080153 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264
JBrowse link
G Sdsl serine dehydratase-like increases expression EXP Ketamine results in increased expression of SDSL mRNA CTD PMID:20080153 NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
JBrowse link
G Senp7 SUMO specific peptidase 7 decreases expression EXP Ketamine results in decreased expression of SENP7 mRNA CTD PMID:20080153 NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711
JBrowse link
G Septin4 septin 4 increases expression EXP Ketamine results in increased expression of SEPTIN4 mRNA CTD PMID:20080153 NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768
JBrowse link
G Serpinb1a serpin family B member 1A increases expression EXP Ketamine results in increased expression of SERPINB1A mRNA CTD PMID:20080153 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Sesn1 sestrin 1 increases expression EXP Ketamine results in increased expression of SESN1 mRNA CTD PMID:20080153 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Setmar SET domain and mariner transposase fusion gene decreases expression EXP Ketamine results in decreased expression of SETMAR mRNA CTD PMID:20080153 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP Ketamine results in decreased expression of SFPQ mRNA CTD PMID:20080153 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sh2b2 SH2B adaptor protein 2 decreases expression EXP Ketamine results in decreased expression of SH2B2 mRNA CTD PMID:20080153 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
JBrowse link
G Shoc2 SHOC2 leucine-rich repeat scaffold protein decreases expression EXP Ketamine results in decreased expression of SHOC2 mRNA CTD PMID:20080153 NCBI chr 1:252,958,939...253,048,820
Ensembl chr 1:252,959,723...253,047,337
JBrowse link
G Slain2 SLAIN motif family, member 2 decreases expression EXP Ketamine results in decreased expression of SLAIN2 mRNA CTD PMID:20080153 NCBI chr14:35,236,034...35,314,186
Ensembl chr14:35,236,041...35,304,678
JBrowse link
G Slc15a5 solute carrier family 15, member 5 decreases expression EXP Ketamine results in decreased expression of SLC15A5 mRNA CTD PMID:20080153 NCBI chr 4:170,878,021...170,971,620
Ensembl chr 4:170,878,021...170,971,620
JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression EXP Ketamine results in increased expression of SLC17A7 mRNA CTD PMID:20080153 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression
multiple interactions
EXP
ISO
Ketamine results in increased expression of SLC1A2 mRNA
[Guanosine co-treated with Ketamine] results in increased expression of SLC1A2 protein
CTD PMID:20080153 PMID:36878458 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc20a2 solute carrier family 20 member 2 increases expression EXP Ketamine results in increased expression of SLC20A2 mRNA CTD PMID:20080153 NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711
JBrowse link
G Slc25a1 solute carrier family 25 member 1 decreases expression EXP Ketamine results in decreased expression of SLC25A1 mRNA CTD PMID:20080153 NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
JBrowse link
G Slc26a6 solute carrier family 26 member 6 increases expression EXP Ketamine results in increased expression of SLC26A6 mRNA CTD PMID:20080153 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP Ketamine results in increased expression of SLC2A2 mRNA CTD PMID:20080153 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a5 solute carrier family 2 member 5 increases expression EXP Ketamine results in increased expression of SLC2A5 mRNA CTD PMID:20080153 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc2a6 solute carrier family 2 member 6 decreases expression EXP Ketamine results in decreased expression of SLC2A6 mRNA CTD PMID:20080153 NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
JBrowse link
G Slc30a6 solute carrier family 30 member 6 decreases expression EXP Ketamine results in decreased expression of SLC30A6 mRNA CTD PMID:20080153 NCBI chr 6:21,020,931...21,050,785
Ensembl chr 6:21,020,931...21,050,785
JBrowse link
G Slc32a1 solute carrier family 32 member 1 increases expression EXP Ketamine results in increased expression of SLC32A1 mRNA CTD PMID:20080153 NCBI chr 3:147,267,373...147,271,842
Ensembl chr 3:147,267,373...147,271,844
JBrowse link
G Slc35e3 solute carrier family 35, member E3 decreases expression EXP Ketamine results in decreased expression of SLC35E3 mRNA CTD PMID:20080153 NCBI chr 7:53,337,091...53,350,152
Ensembl chr 7:53,337,095...53,350,165
JBrowse link
G Slc38a3 solute carrier family 38, member 3 increases expression EXP Ketamine results in increased expression of SLC38A3 mRNA CTD PMID:20080153 NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
JBrowse link
G Slc38a5 solute carrier family 38, member 5 decreases expression EXP Ketamine results in decreased expression of SLC38A5 mRNA CTD PMID:20080153 NCBI chr  X:14,213,727...14,222,498
Ensembl chr  X:14,213,729...14,222,498
JBrowse link
G Slc39a12 solute carrier family 39 member 12 increases expression EXP Ketamine results in increased expression of SLC39A12 mRNA CTD PMID:20080153 NCBI chr17:77,353,761...77,440,384
Ensembl chr17:77,353,805...77,440,353
JBrowse link
G Slc45a4 solute carrier family 45, member 4 increases expression EXP Ketamine results in increased expression of SLC45A4 mRNA CTD PMID:20080153 NCBI chr 7:105,478,886...105,550,160
Ensembl chr 7:105,481,792...105,550,170
JBrowse link
G Slc52a2 solute carrier family 52 member 2 decreases expression EXP Ketamine results in decreased expression of SLC52A2 mRNA CTD PMID:20080153 NCBI chr 7:108,246,003...108,267,642
Ensembl chr 7:108,262,612...108,268,034
JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression EXP Ketamine results in decreased expression of SLC5A3 mRNA CTD PMID:20080153 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc6a2 solute carrier family 6 member 2 multiple interactions
decreases activity
ISO [Ketamine co-treated with Xylenes] results in decreased activity of SLC6A2 protein
Ketamine results in decreased activity of SLC6A2 protein
CTD PMID:17934728 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Ketamine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:31009648 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc7a10 solute carrier family 7 member 10 increases expression EXP Ketamine results in increased expression of SLC7A10 mRNA CTD PMID:20080153 NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071
JBrowse link
G Slc9a1 solute carrier family 9 member A1 increases expression EXP Ketamine results in increased expression of SLC9A1 mRNA CTD PMID:20080153 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Slc9a6 solute carrier family 9 member A6 decreases expression ISO Ketamine results in decreased expression of SLC9A6 protein CTD PMID:35378374 NCBI chr  X:134,430,677...134,486,747
Ensembl chr  X:134,420,756...134,485,375
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 decreases expression EXP Ketamine results in decreased expression of SLCO1C1 mRNA CTD PMID:20080153 NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289
JBrowse link
G Slco5a1 solute carrier organic anion transporter family, member 5A1 decreases expression EXP Ketamine results in decreased expression of SLCO5A1 mRNA CTD PMID:20080153 NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913
JBrowse link
G Sltm SAFB-like, transcription modulator decreases expression EXP Ketamine results in decreased expression of SLTM mRNA CTD PMID:20080153 NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825
JBrowse link
G Smarca1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 decreases expression EXP Ketamine results in decreased expression of SMARCA1 mRNA CTD PMID:20080153 NCBI chr  X:126,980,201...127,066,385
Ensembl chr  X:126,994,947...127,066,347
JBrowse link
G Smc6 structural maintenance of chromosomes 6 decreases expression EXP Ketamine results in decreased expression of SMC6 mRNA CTD PMID:20080153 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 decreases expression EXP Ketamine results in decreased expression of SMOC2 mRNA CTD PMID:20080153 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693
JBrowse link
G Smox spermine oxidase increases expression EXP Ketamine results in increased expression of SMOX mRNA CTD PMID:20080153 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression ISO Ketamine results in increased expression of SNAI1 mRNA CTD PMID:28331066 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO Ketamine results in increased expression of SNAI2 mRNA CTD PMID:28331066 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Snapc3 small nuclear RNA activating complex, polypeptide 3 decreases expression EXP Ketamine results in decreased expression of SNAPC3 mRNA CTD PMID:20080153 NCBI chr 5:97,817,827...97,868,494
Ensembl chr 5:97,817,947...97,844,650
JBrowse link
G Snorc secondary ossification center associated regulator of chondrocyte maturation increases expression EXP Ketamine results in increased expression of SNORC mRNA CTD PMID:20080153 NCBI chr 9:88,140,510...88,145,527
Ensembl chr 9:88,140,419...88,145,891
JBrowse link
G Snta1 syntrophin, alpha 1 increases expression EXP Ketamine results in increased expression of SNTA1 mRNA CTD PMID:20080153 NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709
JBrowse link
G Sntg2 syntrophin, gamma 2 decreases expression EXP Ketamine results in decreased expression of SNTG2 mRNA CTD PMID:20080153 NCBI chr 6:46,801,893...47,003,390
Ensembl chr 6:46,801,377...47,003,372
JBrowse link
G Snx16 sorting nexin 16 decreases expression EXP Ketamine results in decreased expression of SNX16 mRNA CTD PMID:20080153 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression EXP Ketamine results in decreased expression of SOCS5 mRNA CTD PMID:20080153 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Ketamine results in increased expression of SOD3 mRNA CTD PMID:20080153 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sorcs1 sortilin-related VPS10 domain containing receptor 1 decreases expression EXP Ketamine results in decreased expression of SORCS1 mRNA CTD PMID:20080153 NCBI chr 1:249,080,662...249,594,520
Ensembl chr 1:249,081,355...249,594,507
JBrowse link
G Sox11 SRY-box transcription factor 11 decreases expression EXP Ketamine results in decreased expression of SOX11 mRNA CTD PMID:20080153 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Sox4 SRY-box transcription factor 4 decreases expression EXP Ketamine results in decreased expression of SOX4 mRNA CTD PMID:20080153 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Spatc1 spermatogenesis and centriole associated 1 decreases expression EXP Ketamine results in decreased expression of SPATC1 mRNA CTD PMID:20080153 NCBI chr 7:107,980,857...108,007,716
Ensembl chr 7:107,983,796...108,007,479
JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A increases expression EXP Ketamine results in increased expression of SPDYA mRNA CTD PMID:20080153 NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP Ketamine results in increased expression of SPSB1 mRNA CTD PMID:20080153 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 increases expression EXP Ketamine results in increased expression of SPTBN4 mRNA CTD PMID:20080153 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
JBrowse link
G Sqle squalene epoxidase decreases expression EXP Ketamine results in decreased expression of SQLE mRNA CTD PMID:20080153 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Ketamine results in increased expression of SQSTM1 mRNA; Ketamine results in increased expression of SQSTM1 protein CTD PMID:34487425 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP Ketamine results in increased expression of SREBF1 mRNA CTD PMID:20080153 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srpk1 SRSF protein kinase 1 decreases expression EXP Ketamine results in decreased expression of SRPK1 mRNA CTD PMID:20080153 NCBI chr20:6,645,809...6,682,448
Ensembl chr20:6,645,809...6,682,134
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 decreases expression EXP Ketamine results in decreased expression of SFRS6 mRNA CTD PMID:20080153 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
JBrowse link
G Ssr1 signal sequence receptor subunit 1 increases expression EXP Ketamine results in increased expression of SSR1 mRNA CTD PMID:20080153 NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression EXP Ketamine results in decreased expression of SSTR1 mRNA CTD PMID:20080153 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
JBrowse link
G Stim1 stromal interaction molecule 1 increases expression EXP Ketamine results in increased expression of STIM1 mRNA CTD PMID:20080153 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP Ketamine results in increased expression of SULT1A1 mRNA CTD PMID:20080153 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Suox sulfite oxidase decreases expression EXP Ketamine results in decreased expression of SUOX mRNA CTD PMID:20080153 NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
JBrowse link
G Syn1 synapsin I multiple interactions
increases expression
ISO Ketamine inhibits the reaction [Corticosterone results in decreased expression of SYN1 protein]; Sirolimus inhibits the reaction [Ketamine results in increased expression of SYN1 protein] CTD PMID:33022268 PMID:33872575 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Syt12 synaptotagmin 12 increases expression EXP Ketamine results in increased expression of SYT12 mRNA CTD PMID:20080153 NCBI chr 1:201,729,307...201,760,192
Ensembl chr 1:201,730,371...201,759,609
JBrowse link
G Sytl2 synaptotagmin-like 2 increases expression EXP Ketamine results in increased expression of SYTL2 mRNA CTD PMID:20080153 NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222
JBrowse link
G Tac3 tachykinin precursor 3 increases expression EXP Ketamine results in increased expression of TAC2 mRNA CTD PMID:20080153 NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 decreases expression EXP Ketamine results in decreased expression of TACSTD2 mRNA CTD PMID:20080153 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
G Tafa1 TAFA chemokine like family member 1 decreases expression EXP Ketamine results in decreased expression of TAFA1 mRNA CTD PMID:20080153 NCBI chr 4:128,738,028...129,244,223
Ensembl chr 4:128,739,313...129,243,777
JBrowse link
G Tagln3 transgelin 3 increases expression EXP Ketamine results in increased expression of TAGLN3 protein CTD PMID:18504422 NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485
JBrowse link
G Tax1bp3 Tax1 binding protein 3 decreases expression EXP Ketamine results in decreased expression of TAX1BP3 mRNA CTD PMID:20080153 NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363
JBrowse link
G Tbc1d10b TBC1 domain family, member 10b decreases expression EXP Ketamine results in decreased expression of TBC1D10B mRNA CTD PMID:20080153 NCBI chr 1:181,814,972...181,826,628
Ensembl chr 1:181,814,972...181,826,628
JBrowse link
G Tbccd1 TBCC domain containing 1 decreases expression EXP Ketamine results in decreased expression of TBCCD1 mRNA CTD PMID:20080153 NCBI chr11:78,168,386...78,205,314
Ensembl chr11:78,168,388...78,205,523
JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression EXP Ketamine results in increased expression of TEF mRNA CTD PMID:20080153 NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
JBrowse link
G Tekt2 tektin 2 increases expression EXP Ketamine results in increased expression of TEKT2 mRNA CTD PMID:20080153 NCBI chr 5:138,619,665...138,623,301
Ensembl chr 5:138,619,667...138,623,204
JBrowse link
G Tes testin LIM domain protein decreases expression EXP Ketamine results in decreased expression of TES mRNA CTD PMID:20080153 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829
JBrowse link
G Tesc tescalcin increases expression EXP Ketamine results in increased expression of TESC mRNA CTD PMID:20080153 NCBI chr12:38,521,832...38,555,665
Ensembl chr12:38,521,861...38,555,824
JBrowse link
G Tf transferrin increases expression EXP Ketamine results in increased expression of TF mRNA CTD PMID:20080153 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfap2d transcription factor AP-2 delta decreases expression EXP Ketamine results in decreased expression of TFAP2D mRNA CTD PMID:20080153 NCBI chr 9:21,680,577...21,744,840
Ensembl chr 9:21,680,577...21,740,728
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 increases expression EXP Ketamine results in increased expression of TFE3 mRNA CTD PMID:20080153 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
increases secretion
EXP
ISO
Ketamine results in increased expression of TGFB1 protein
Ketamine results in increased expression of TGFB1 mRNA
Ketamine results in increased secretion of TGFB1 protein
CTD PMID:28331066 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression ISO Ketamine results in increased expression of TGFBR1 mRNA CTD PMID:28331066 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Ketamine results in increased expression of TGFBR2 mRNA CTD PMID:28331066 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Thnsl2 threonine synthase-like 2 increases expression EXP Ketamine results in increased expression of THNSL2 mRNA CTD PMID:20080153 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP Ketamine results in increased expression of THRSP mRNA CTD PMID:20080153 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Thumpd3 THUMP domain containing 3 decreases expression EXP Ketamine results in decreased expression of THUMPD3 mRNA CTD PMID:20080153 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246
JBrowse link
G Thy1 Thy-1 cell surface antigen increases expression EXP Ketamine results in increased expression of THY1 mRNA CTD PMID:20080153 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein decreases expression EXP Ketamine results in decreased expression of TIA1 mRNA CTD PMID:20080153 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586
JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain increases expression EXP Ketamine results in increased expression of TIFA mRNA CTD PMID:20080153 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
JBrowse link
G Tigd2 tigger transposable element derived 2 increases expression EXP Ketamine results in increased expression of TIGD2 mRNA CTD PMID:20080153 NCBI chr 4:88,414,366...88,417,458
Ensembl chr 4:88,414,518...88,417,785
JBrowse link
G Tlcd3a TLC domain containing 3A decreases expression EXP Ketamine results in decreased expression of TLCD3A mRNA CTD PMID:20080153 NCBI chr10:61,057,470...61,065,293
Ensembl chr10:61,058,042...61,065,283
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]] CTD PMID:19540866 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 decreases expression EXP Ketamine results in decreased expression of TMEFF1 mRNA CTD PMID:20080153 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493
JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 decreases expression EXP Ketamine results in decreased expression of TMEFF2 mRNA CTD PMID:20080153 NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475
JBrowse link
G Tmem140 transmembrane protein 140 increases expression EXP Ketamine results in increased expression of TMEM140 mRNA CTD PMID:20080153 NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
JBrowse link
G Tmem200a transmembrane protein 200A decreases expression EXP Ketamine results in decreased expression of TMEM200A mRNA CTD PMID:20080153 NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:19,323,829...19,406,453
JBrowse link
G Tmem222 transmembrane protein 222 increases expression EXP Ketamine results in increased expression of TMEM222 mRNA CTD PMID:20080153 NCBI chr 5:145,465,847...145,477,932
Ensembl chr 5:145,465,847...145,484,491
JBrowse link
G Tmem248 transmembrane protein 248 increases expression EXP Ketamine results in increased expression of TMEM248 mRNA CTD PMID:20080153 NCBI chr12:26,430,775...26,457,105
Ensembl chr12:26,432,953...26,457,105
JBrowse link
G Tmem74 transmembrane protein 74 decreases expression EXP Ketamine results in decreased expression of TMEM74 mRNA CTD PMID:20080153 NCBI chr 7:74,929,290...74,937,929
Ensembl chr 7:74,931,694...74,937,934
JBrowse link
G Tmem74b transmembrane protein 74B decreases expression EXP Ketamine results in decreased expression of TMEM74B mRNA CTD PMID:20080153 NCBI chr 3:140,219,592...140,224,208
Ensembl chr 3:140,219,412...140,235,872
JBrowse link
G Tmpo thymopoietin decreases expression EXP Ketamine results in decreased expression of TMPO mRNA CTD PMID:20080153 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tmtc4 transmembrane O-mannosyltransferase targeting cadherins 4 decreases expression EXP Ketamine results in decreased expression of TMTC4 mRNA CTD PMID:20080153 NCBI chr15:100,000,157...100,056,573
Ensembl chr15:100,000,152...100,056,543
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
affects expression
decreases expression
ISO
EXP
IEP
Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Ketamine results in increased expression of TNF protein
Ketamine co-treated with xylazine inhibits the reaction [lipopolysaccharide increases expression of Tnf protein in serum and mucosa of stomach]
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of TNF protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
Ozone inhibits the reaction [Ketamine results in decreased expression of TNF mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of TNF protein]
CTD
RGD
PMID:15207037 PMID:15207038 PMID:15720977 PMID:19540866 PMID:22245128 More... RGD:14995427 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip1 TNF alpha induced protein 1 decreases expression EXP Ketamine results in decreased expression of TNFAIP1 mRNA CTD PMID:20080153 NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression EXP Ketamine results in decreased expression of TNFRSF11B mRNA CTD PMID:20080153 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnnc2 troponin C2, fast skeletal type increases expression EXP Ketamine results in increased expression of TNNC2 mRNA CTD PMID:20080153 NCBI chr 3:153,513,272...153,516,033
Ensembl chr 3:153,513,271...153,516,029
JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression ISO Ketamine results in increased expression of TNNT1 mRNA CTD PMID:19162068 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Tnpo1 transportin 1 decreases expression EXP Ketamine results in decreased expression of TNPO1 mRNA CTD PMID:20080153 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Tns3 tensin 3 increases expression EXP Ketamine results in increased expression of TNS3 mRNA CTD PMID:20080153 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Ketamine results in increased expression of TP53 protein CTD PMID:19919587 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP Ketamine results in increased expression of TPM1 mRNA CTD PMID:20080153 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Tpm4 tropomyosin 4 decreases expression EXP Ketamine results in decreased expression of TPM4 mRNA CTD PMID:20080153 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tra2a transformer 2 alpha decreases expression EXP Ketamine results in decreased expression of TRA2A mRNA CTD PMID:20080153 NCBI chr 4:78,220,838...78,239,737
Ensembl chr 4:78,220,883...78,239,712
JBrowse link
G Traip TRAF-interacting protein increases expression EXP Ketamine results in increased expression of TRAIP mRNA CTD PMID:20080153 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 increases expression EXP Ketamine results in increased expression of TREM2 mRNA CTD PMID:20080153 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trh thyrotropin releasing hormone increases expression EXP Ketamine results in increased expression of TRH mRNA CTD PMID:20080153 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trim13 tripartite motif-containing 13 decreases expression EXP Ketamine results in decreased expression of TRIM13 mRNA CTD PMID:20080153 NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
JBrowse link
G Trim36 tripartite motif-containing 36 decreases expression EXP Ketamine results in decreased expression of TRIM36 mRNA CTD PMID:20080153 NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859
JBrowse link
G Trim39 tripartite motif-containing 39 decreases expression EXP Ketamine results in decreased expression of TRIM39 mRNA CTD PMID:20080153 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
G Trim54 tripartite motif-containing 54 increases expression EXP Ketamine results in increased expression of TRIM54 mRNA CTD PMID:20080153 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 decreases expression
multiple interactions
EXP Ketamine results in decreased expression of TRPC3 mRNA; Ketamine results in decreased expression of TRPC3 protein
Chir 99021 promotes the reaction [Ketamine results in decreased expression of TRPC3 protein]
CTD PMID:36334642 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 decreases expression EXP Ketamine results in decreased expression of TRPV2 mRNA CTD PMID:20080153 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression
multiple interactions
EXP Ketamine results in increased expression of TRPV4 mRNA; Ketamine results in increased expression of TRPV4 protein
TRPV4 protein affects the reaction [Ketamine results in decreased activity of CAT protein]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 protein]; TRPV4 protein affects the reaction [Ketamine results in increased cleavage of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of CASP3 mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL1B protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL6 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of TNF protein]; TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of NFKBIA protein]; TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of RELA protein]
CTD PMID:33536391 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
G Tsen2 tRNA splicing endonuclease subunit 2 decreases expression EXP Ketamine results in decreased expression of TSEN2 mRNA CTD PMID:20080153 NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
JBrowse link
G Tspan14 tetraspanin 14 decreases expression EXP Ketamine results in decreased expression of TSPAN14 mRNA CTD PMID:20080153 NCBI chr16:16,784,242...16,841,368
Ensembl chr16:16,783,234...16,841,400
JBrowse link
G Tspan33 tetraspanin 33 increases expression EXP Ketamine results in increased expression of TSPAN33 mRNA CTD PMID:20080153 NCBI chr 4:58,305,378...58,330,013
Ensembl chr 4:58,305,437...58,328,940
JBrowse link
G Tspo translocator protein multiple interactions EXP [Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein] CTD PMID:33823148 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Ttc14 tetratricopeptide repeat domain 14 decreases expression EXP Ketamine results in decreased expression of TTC14 mRNA CTD PMID:20080153 NCBI chr 2:116,653,543...116,665,072
Ensembl chr 2:116,653,595...116,664,158
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B decreases expression EXP Ketamine results in decreased expression of TTC21B mRNA CTD PMID:20080153 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903
JBrowse link
G Ttll1 TTL family tubulin polyglutamylase complex subunit L1 decreases expression EXP Ketamine results in decreased expression of TTLL1 mRNA CTD PMID:20080153 NCBI chr 7:114,619,509...114,648,850
Ensembl chr 7:114,619,508...114,648,761
JBrowse link
G Ttll7 tubulin tyrosine ligase like 7 decreases expression EXP Ketamine results in decreased expression of TTLL7 mRNA CTD PMID:20080153 NCBI chr 2:235,765,786...235,889,047
Ensembl chr 2:235,765,835...235,885,047
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Ketamine results in decreased expression of TUBA1C protein CTD PMID:18504422 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tuba4a tubulin, alpha 4A increases expression EXP Ketamine results in increased expression of TUBA4A mRNA CTD PMID:20080153 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO Ketamine results in increased expression of TWIST1 mRNA CTD PMID:28331066 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Txndc17 thioredoxin domain containing 17 decreases expression EXP Ketamine results in decreased expression of TXNDC17 mRNA CTD PMID:20080153 NCBI chr10:56,832,749...56,835,721 JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP Ketamine results in increased expression of TXNIP mRNA CTD PMID:20080153 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Tyms thymidylate synthetase decreases expression EXP Ketamine results in decreased expression of TYMS mRNA CTD PMID:20080153 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G U2surp U2 snRNP-associated SURP domain containing decreases expression EXP Ketamine results in decreased expression of U2SURP mRNA CTD PMID:20080153 NCBI chr 8:96,018,932...96,075,795
Ensembl chr 8:96,022,957...96,075,691
JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 decreases expression EXP Ketamine results in decreased expression of UAP1 mRNA CTD PMID:20080153 NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
JBrowse link
G Ubap1 ubiquitin-associated protein 1 decreases expression EXP Ketamine results in decreased expression of UBAP1 mRNA CTD PMID:20080153 NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:56,520,743...56,561,152
JBrowse link
G Ubap2 ubiquitin-associated protein 2 decreases expression EXP Ketamine results in decreased expression of UBAP2 mRNA CTD PMID:20080153 NCBI chr 5:56,348,243...56,437,403
Ensembl chr 5:56,348,246...56,437,049
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B increases expression EXP Ketamine results in increased expression of UBE2B mRNA CTD PMID:20080153 NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665
JBrowse link
G Ubqln1 ubiquilin 1 decreases expression EXP Ketamine results in decreased expression of UBQLN1 mRNA CTD PMID:20080153 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression EXP Ketamine results in decreased expression of UGDH mRNA CTD PMID:20080153 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Unc5c unc-5 netrin receptor C decreases expression EXP Ketamine results in decreased expression of UNC5C mRNA CTD PMID:20080153 NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217
JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression EXP Ketamine results in increased expression of USP2 mRNA CTD PMID:20080153 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Usp43 ubiquitin specific peptidase 43 decreases expression EXP Ketamine results in decreased expression of USP43 mRNA CTD PMID:20080153 NCBI chr10:52,549,200...52,611,168
Ensembl chr10:52,548,963...52,611,533
JBrowse link
G Utp6 UTP6 small subunit processome component decreases expression EXP Ketamine results in decreased expression of UTP6 mRNA CTD PMID:20080153 NCBI chr10:64,897,321...64,927,997
Ensembl chr10:64,897,328...64,927,997
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcan versican decreases expression EXP Ketamine results in decreased expression of VCAN mRNA CTD PMID:20080153 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 decreases expression EXP Ketamine results in decreased expression of VCPIP1 mRNA CTD PMID:20080153 NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040
JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression EXP Ketamine results in increased expression of VDAC2 protein CTD PMID:18504422 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vim vimentin increases expression
multiple interactions
ISO
EXP
Ketamine results in increased expression of VIM mRNA
2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of VIM protein]
CTD PMID:28331066 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A decreases expression EXP Ketamine results in decreased expression of VPS13A mRNA CTD PMID:20080153 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555
JBrowse link
G Vps36 vacuolar protein sorting 36 homolog decreases expression EXP Ketamine results in decreased expression of VPS36 mRNA CTD PMID:20080153 NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810
JBrowse link
G Washc3 WASH complex subunit 3 decreases expression EXP Ketamine results in decreased expression of WASHC3 mRNA CTD PMID:20080153 NCBI chr 7:22,621,078...22,665,550
Ensembl chr 7:22,621,078...22,690,696
JBrowse link
G Wdr36 WD repeat domain 36 decreases expression EXP Ketamine results in decreased expression of WDR36 mRNA CTD PMID:20080153 NCBI chr18:24,473,657...24,501,773
Ensembl chr18:24,473,663...24,508,092
JBrowse link
G Wdr47 WD repeat domain 47 decreases expression EXP Ketamine results in decreased expression of WDR47 mRNA CTD PMID:20080153 NCBI chr 2:196,226,757...196,287,739
Ensembl chr 2:196,205,238...196,287,739
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A increases expression EXP Ketamine results in increased expression of WFDC6A mRNA CTD PMID:20080153 NCBI chr 3:153,305,336...153,309,144
Ensembl chr 3:153,305,336...153,309,144
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein increases expression EXP Ketamine results in increased expression of WFS1 mRNA CTD PMID:20080153 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
JBrowse link
G Wrn WRN RecQ like helicase decreases expression EXP Ketamine results in decreased expression of WRN mRNA CTD PMID:20080153 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
JBrowse link
G Wtap WT1 associated protein increases expression EXP Ketamine results in increased expression of WTAP mRNA CTD PMID:20080153 NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Ketamine affects the expression of and affects the splicing of XBP1 mRNA CTD PMID:35728656 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xylt2 xylosyltransferase 2 increases expression EXP Ketamine results in increased expression of XYLT2 mRNA CTD PMID:20080153 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
G Yars2 tyrosyl-tRNA synthetase 2 decreases expression EXP Ketamine results in decreased expression of YARS2 mRNA CTD PMID:20080153 NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125
JBrowse link
G Ybx3 Y box binding protein 3 decreases expression EXP Ketamine results in decreased expression of YBX3 mRNA CTD PMID:20080153 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
G Yjefn3 YjeF N-terminal domain containing 3 increases expression EXP Ketamine results in increased expression of YJEFN3 mRNA CTD PMID:20080153 NCBI chr16:19,533,742...19,539,759
Ensembl chr16:19,533,788...19,539,728
JBrowse link
G Ypel5 yippee-like 5 increases expression EXP Ketamine results in increased expression of YPEL5 mRNA CTD PMID:20080153 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691
JBrowse link
G Yy1 YY1 transcription factor decreases expression EXP Ketamine results in decreased expression of YY1 mRNA CTD PMID:20080153 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zbed5 zinc finger BED-type containing 5 decreases expression EXP Ketamine results in decreased expression of ZBED5 mRNA CTD PMID:20080153 NCBI chr12:26,807,652...26,813,706
Ensembl chr12:26,807,600...26,813,664
JBrowse link
G Zbtb8b zinc finger and BTB domain containing 8b decreases expression EXP Ketamine results in decreased expression of ZBTB8B mRNA CTD PMID:20080153 NCBI chr 5:141,765,925...141,781,619
Ensembl chr 5:141,766,309...141,781,600
JBrowse link
G Zcchc9 zinc finger CCHC-type containing 9 decreases expression EXP Ketamine results in decreased expression of ZCCHC9 mRNA CTD PMID:20080153 NCBI chr 2:23,038,156...23,048,249
Ensembl chr 2:23,038,317...23,048,217
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 decreases expression EXP Ketamine results in decreased expression of ZDHHC23 mRNA CTD PMID:20080153 NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression EXP Ketamine results in increased expression of ZFAND2A mRNA CTD PMID:20080153 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression EXP Ketamine results in decreased expression of ZFHX4 mRNA CTD PMID:20080153 NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228
JBrowse link
G Zfp36 zinc finger protein 36 increases expression EXP Ketamine results in increased expression of ZFP36 mRNA CTD PMID:20080153 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp524 zinc finger protein 524 decreases expression EXP Ketamine results in decreased expression of ZFP524 mRNA CTD PMID:20080153 NCBI chr 1:68,824,803...68,828,363
Ensembl chr 1:68,824,803...68,828,594
JBrowse link
G Zfp57 zinc finger protein 57 decreases expression EXP Ketamine results in decreased expression of ZFP57 mRNA CTD PMID:20080153 NCBI chr20:1,521,323...1,534,884
Ensembl chr20:1,521,323...1,529,846
JBrowse link
G Zfp638 zinc finger protein 638 decreases expression EXP Ketamine results in decreased expression of ZFP638 mRNA CTD PMID:20080153 NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 decreases expression EXP Ketamine results in decreased expression of ZMYND8 mRNA CTD PMID:20080153 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
JBrowse link
G Znf235-ps1 zinc finger protein 235, pseudogene 1 decreases expression EXP Ketamine results in decreased expression of ZFP61 mRNA CTD PMID:20080153 NCBI chr 1:79,799,766...79,808,543
Ensembl chr 1:79,799,769...79,808,465
JBrowse link
G Znhit6 zinc finger, HIT-type containing 6 decreases expression EXP Ketamine results in decreased expression of ZNHIT6 mRNA CTD PMID:20080153 NCBI chr 2:234,486,686...234,517,952
Ensembl chr 2:234,486,704...234,517,960
JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases expression EXP Ketamine results in decreased expression of ZSWIM5 mRNA CTD PMID:20080153 NCBI chr 5:130,346,733...130,463,791
Ensembl chr 5:130,343,034...130,463,784
JBrowse link
loxoprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn1 claudin 1 increases expression ISO loxoprofen metabolite results in increased expression of CLDN1 protein; loxoprofen results in increased expression of CLDN1 mRNA; loxoprofen results in increased expression of CLDN1 protein CTD PMID:34506768 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn3 claudin 3 increases expression ISO loxoprofen metabolite results in increased expression of CLDN3 protein; loxoprofen results in increased expression of CLDN3 mRNA; loxoprofen results in increased expression of CLDN3 protein CTD PMID:34506768 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Cldn5 claudin 5 increases expression ISO loxoprofen metabolite results in increased expression of CLDN5 protein; loxoprofen results in increased expression of CLDN5 mRNA; loxoprofen results in increased expression of CLDN5 protein CTD PMID:34506768 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO loxoprofen metabolite results in decreased phosphorylation of MAPK1 protein; loxoprofen results in decreased phosphorylation of MAPK1 protein CTD PMID:34506768 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO loxoprofen metabolite results in decreased phosphorylation of MAPK3 protein; loxoprofen results in decreased phosphorylation of MAPK3 protein CTD PMID:34506768 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mpo myeloperoxidase increases activity EXP loxoprofen results in increased activity of MPO protein CTD PMID:20586851 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions
decreases expression
EXP lafutidine inhibits the reaction [loxoprofen results in decreased expression of MUC2] CTD PMID:20586851 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP loxoprofen results in increased expression of NOS2
lafutidine inhibits the reaction [loxoprofen results in increased expression of NOS2]
CTD PMID:20586851 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
lucidenic acid N term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO lucidenic acid N analog results in increased expression of HMOX1 protein CTD PMID:25239868 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
nitisinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLC mRNA CTD PMID:12899938 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA CTD PMID:12899938 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [nitisinone results in decreased activity of HPD protein] which results in decreased expression of HMOX1 mRNA CTD PMID:12899938 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase multiple interactions ISO [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLC mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of HMOX1 mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of NQO1 mRNA CTD PMID:12899938 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [nitisinone results in decreased activity of HPD protein] which results in decreased expression of NQO1 mRNA CTD PMID:12899938 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
omaveloxolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] CTD PMID:32410268 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] CTD PMID:32410268 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein CTD PMID:32410268 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Lep leptin multiple interactions ISO omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein] CTD PMID:32410268 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [omaveloxolone co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA] CTD PMID:32410268 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA] CTD PMID:32410268 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
prostaglandin D2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 increases metabolic processing
increases reduction
decreases response to substance
decreases metabolic processing
multiple interactions
ISO AKR1C3 protein results in increased metabolism of Prostaglandin D2
AKR1C3 protein results in increased reduction of Prostaglandin D2
AKR1C3 protein results in decreased susceptibility to Prostaglandin D2
AKR1C3 protein results in decreased metabolism of Prostaglandin D2
[AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis of 9-deoxy-delta-9-prostaglandin D2; [AKR1C3 protein results in increased reduction of Prostaglandin D2] which results in increased chemical synthesis of Dinoprost; [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2; Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]
CTD PMID:19010312 PMID:19997560 PMID:20036328 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G App amyloid beta precursor protein increases secretion
multiple interactions
ISO APP protein modified form results in increased secretion of Prostaglandin D2
CNB 001 inhibits the reaction [APP protein modified form results in increased secretion of Prostaglandin D2]; Dronabinol inhibits the reaction [APP protein modified form results in increased secretion of Prostaglandin D2]; L 685458 inhibits the reaction [APP protein modified form results in increased secretion of Prostaglandin D2]
CTD PMID:28721267 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases cleavage ISO Prostaglandin D2 results in increased cleavage of ARHGDIB protein CTD PMID:15843042 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
ISO
EXP
Prostaglandin D2 results in increased activity of CASP3 protein
Prostaglandin D2 results in increased cleavage of CASP3 protein
CTD PMID:15843042 PMID:23973622 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Prostaglandin D2 promotes the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:9066782 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of CXCL2 protein; PTGDR protein promotes the reaction [[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of CXCL2 protein]
Prostaglandin D2 results in increased expression of CXCL2 protein
CTD PMID:21166666 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [EGF protein co-treated with Prostaglandin D2] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO EPHX2 gene mutant form promotes the reaction [Aspirin inhibits the reaction [Lipopolysaccharides results in increased abundance of Prostaglandin D2]] CTD PMID:19896470 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Prostaglandin D2 results in increased expression of FABP4 mRNA CTD PMID:9543393 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase multiple interactions ISO [4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine results in increased expression of HPGDS mRNA] which results in decreased abundance of Prostaglandin D2 CTD PMID:21352547 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases abundance
increases expression
increases secretion
ISO
EXP
[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein] results in increased abundance of Prostaglandin D2; Indomethacin inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein] results in increased abundance of Prostaglandin D2]; resveratrol inhibits the reaction [IL1B protein results in increased abundance of Prostaglandin D2]
Prostaglandin D2 results in increased expression of IL1B protein
[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of IL1B protein; PTGDR protein promotes the reaction [[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of IL1B protein]
IL1B protein results in increased secretion of Prostaglandin D2
IL1B protein promotes the reaction [rosiglitazone results in increased secretion of Prostaglandin D2]
CTD PMID:12743569 PMID:12897060 PMID:19751497 PMID:21166666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 multiple interactions ISO 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; [Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2] CTD PMID:23688403 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of IL6 protein; PTGDR protein promotes the reaction [[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of IL6 protein] CTD PMID:21166666 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lypla2 lysophospholipase 2 increases hydrolysis ISO LYPLA2 protein results in increased hydrolysis of Prostaglandin D2 analog CTD PMID:25301951 NCBI chr 5:148,198,466...148,203,062
Ensembl chr 5:148,198,439...148,203,092
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Prostaglandin D2 results in increased phosphorylation of MAPK1 protein CTD PMID:24813642 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Prostaglandin D2 results in increased phosphorylation of MAPK3 protein CTD PMID:24813642 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP [EGF protein co-treated with Prostaglandin D2] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO
EXP
Prostaglandin D2 results in increased cleavage of PARP1 protein CTD PMID:15843042 PMID:23973622 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
affects localization
ISO Prostaglandin D2 affects the localization of and results in increased expression of PPARG protein
Prostaglandin D2 affects the localization of PPARG protein
CTD PMID:23220503 PMID:23943857 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Prostaglandin D2 results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation ISO Prostaglandin D2 results in increased phosphorylation of PPP1R12A protein CTD PMID:24813642 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO 13,14-dihydro-15-ketoprostaglandin D2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; adenosine 5'-O-(3-thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Adenylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Alprostadil inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; BW 245C inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; BW A868C inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; delta(12)-prostaglandin J(2) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Dinoprost inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Dinoprostone inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Guanosine 5'-O-(3-Thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Guanylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Iloprost inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; L 644698 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]; Prostaglandin D2 binds to and results in increased activity of PTGDR protein; ZK 110841 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]
[Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased metabolism of Adenosine; [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased secretion of Adenosine; PTGDR protein promotes the reaction [[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of CXCL2 protein]; PTGDR protein promotes the reaction [[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of IL1B protein]; PTGDR protein promotes the reaction [[Lipopolysaccharides results in increased abundance of Prostaglandin D2] which results in increased expression of IL6 protein]
CTD PMID:9579725 PMID:11562489 PMID:21166666 PMID:27636113 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions
increases activity
affects binding
ISO Endocannabinoids inhibits the reaction [Prostaglandin D2 binds to and results in increased activity of PTGDR2 protein]; Prostaglandin D2 binds to and results in increased activity of PTGDR2 protein; ramatroban inhibits the reaction [Prostaglandin D2 binds to and results in increased activity of PTGDR2 protein]
Prostaglandin D2 results in increased activity of PTGDR2 protein
13,14-dihydro-15-ketoprostaglandin D2 inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]; 5-hydroxyindomethacin inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]; Indomethacin inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]; ramatroban inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]; sulindac sulfide inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]; zomepirac inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]
CTD PMID:11801628 PMID:12721327 PMID:15563582 PMID:16256979 PMID:21916510 More... NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213
JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions ISO Prostaglandin D2 binds to and results in increased activity of PTGER2 protein CTD PMID:27636113 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [2-phenylphenol binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [Acetaminophen results in increased expression of PTGS2 mRNA] which results in increased chemical synthesis of Prostaglandin D2; [Chlorpropham binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [cypermethrin binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [cyprodinil binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [enilconazole binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [fludioxonil binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [Ibuprofen binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [Linuron binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [Methiocarb binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [Nanotubes, Carbon co-treated with PTGS2 gene mutant form] results in increased abundance of Prostaglandin D2; [pirimiphos methyl binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [PTGS2 gene mutant form results in increased susceptibility to Kainic Acid] which results in increased abundance of Prostaglandin D2; [PTGS2 gene mutant form results in increased susceptibility to Nanotubes, Carbon] which results in increased abundance of Prostaglandin D2; [pyrimethanil binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2; [tebuconazole binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:11743745 PMID:18834901 PMID:23642096 PMID:26359731 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO Prostaglandin D2 results in increased expression of RORC mRNA CTD PMID:9543393 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Slc22a22 solute carrier family 22 member 22 affects binding ISO Prostaglandin D2 binds to SLC22A22 protein CTD PMID:20448048 NCBI chr 7:88,720,425...88,750,111
Ensembl chr 7:88,720,427...88,750,111
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Prostaglandin D2 promotes the reaction [Kallidin results in increased secretion of TAC1 protein] CTD PMID:16039053 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tg thyroglobulin multiple interactions
increases expression
ISO Prostaglandin D2 promotes the reaction [TSHB protein results in increased expression of TG protein]
Prostaglandin D2 results in increased expression of TG protein
CTD PMID:11078701 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases response to substance ISO Prostaglandin D2 results in decreased susceptibility to TGFB1 protein CTD PMID:20719937 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
ISO [Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein] results in increased abundance of Prostaglandin D2; Indomethacin inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein] results in increased abundance of Prostaglandin D2]
TNF protein results in increased abundance of Prostaglandin D2
CTD PMID:1993070 PMID:12743569 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression
increases secretion
multiple interactions
ISO Prostaglandin D2 results in increased expression of TNFRSF11B mRNA
Prostaglandin D2 results in increased secretion of TNFRSF11B protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Prostaglandin D2 results in increased secretion of TNFRSF11B protein]; pyrazolanthrone inhibits the reaction [Prostaglandin D2 results in increased secretion of TNFRSF11B protein]; resveratrol inhibits the reaction [Prostaglandin D2 results in increased expression of TNFRSF11B mRNA]; resveratrol inhibits the reaction [Prostaglandin D2 results in increased secretion of TNFRSF11B protein]; SB 203580 inhibits the reaction [Prostaglandin D2 results in increased secretion of TNFRSF11B protein]; SRT1720 inhibits the reaction [Prostaglandin D2 results in increased expression of TNFRSF11B mRNA]; SRT1720 inhibits the reaction [Prostaglandin D2 results in increased secretion of TNFRSF11B protein]
CTD PMID:24813642 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO Prostaglandin D2 promotes the reaction [TSHB protein results in increased expression of TG protein] CTD PMID:11078701 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Ucp2 uncoupling protein 2 affects chemical synthesis ISO UCP2 protein affects the chemical synthesis of Prostaglandin D2 CTD PMID:19846869 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
prostaglandin D3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO prostaglandin D3 promotes the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:12573452 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO prostaglandin D3 promotes the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:12573452 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased expression of ABCA1 mRNA]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] which results in increased expression of ABCA1 mRNA CTD PMID:12595494 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis of 9-deoxy-delta-9-prostaglandin D2 CTD PMID:20036328 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [APOA1 protein results in increased transport of Cholesterol] CTD PMID:12595494 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases cleavage ISO 9-deoxy-delta-9-prostaglandin D2 results in increased cleavage of ARHGDIB protein CTD PMID:15843042 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
9-deoxy-delta-9-prostaglandin D2 results in increased activity of CASP3 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of CASP3 protein
CTD PMID:15843042 PMID:23973622 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] results in increased activity of CEBPB protein CTD PMID:15150131 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO 9-deoxy-delta-9-prostaglandin D2 results in decreased expression of CES1 mRNA CTD PMID:11409902 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 promotes the reaction [arsenite results in increased expression of CRYAB mRNA]; 9-deoxy-delta-9-prostaglandin D2 promotes the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:9066782 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Ep300 E1A binding protein p300 decreases activity ISO 9-deoxy-delta-9-prostaglandin D2 results in decreased activity of EP300 protein CTD PMID:22141352 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLC mRNA; 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLC protein CTD PMID:18332871 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLM mRNA; 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLM protein CTD PMID:18332871 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression
ISO [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein]
9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 mRNA; 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein
CTD PMID:14662774 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects metabolic processing ISO GSTA1 protein affects the metabolism of 9-deoxy-delta-9-prostaglandin D2 CTD PMID:9084911 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
affects metabolic processing
increases expression
EXP
ISO
[9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter]; [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] results in increased expression of GSTA2 mRNA; [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] results in increased expression of GSTA2 protein
GSTA2 protein affects the metabolism of 9-deoxy-delta-9-prostaglandin D2
9-deoxy-delta-9-prostaglandin D2 results in increased expression of GSTA2 protein
CTD PMID:9084911 PMID:15150131 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects metabolic processing ISO GSTM1 protein affects the metabolism of 9-deoxy-delta-9-prostaglandin D2 CTD PMID:9084911 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO 9-deoxy-delta-9-prostaglandin D2 results in increased expression of JUN protein modified form CTD PMID:11401521 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] results in increased activity of NFE2L2 protein CTD PMID:15150131 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased expression of ABCA1 mRNA]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased transport of Cholesterol]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] which results in increased expression of NR1H3 mRNA CTD PMID:12595494 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO
EXP
9-deoxy-delta-9-prostaglandin D2 results in increased cleavage of PARP1 protein
[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein
CTD PMID:15843042 PMID:23973622 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
increases expression
multiple interactions
ISO
EXP
9-deoxy-delta-9-prostaglandin D2 results in increased activity of PPARG protein
9-deoxy-delta-9-prostaglandin D2 results in increased expression of PPARG mRNA
9-deoxy-delta-9-prostaglandin D2 promotes the reaction [PPARG protein alternative form results in decreased activity of SLC2A4 promoter]; [9-deoxy-delta-9-prostaglandin D2 co-treated with Alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter]
9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased expression of ABCA1 mRNA]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased transport of Cholesterol]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [APOA1 protein results in increased transport of Cholesterol]; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] which results in increased expression of ABCA1 mRNA; [9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] which results in increased expression of NR1H3 mRNA; Ethanol inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased activity of PPARG protein]
CTD PMID:11343236 PMID:12595494 PMID:12777391 PMID:14512786 PMID:14662774 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO 9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PTGDR protein; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions EXP [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter] CTD PMID:15150131 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 promotes the reaction [PPARG protein alternative form results in decreased activity of SLC2A4 promoter] CTD PMID:12777391 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Tg thyroglobulin multiple interactions
increases expression
ISO 9-deoxy-delta-9-prostaglandin D2 promotes the reaction [TSHB protein results in increased expression of TG protein]
9-deoxy-delta-9-prostaglandin D2 results in increased expression of TG protein
CTD PMID:11078701 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO 9-deoxy-delta-9-prostaglandin D2 promotes the reaction [TSHB protein results in increased expression of TG protein] CTD PMID:11078701 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
rubiarbonone C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects activity ISO rubiarbonone C affects the activity of CYP3A4 protein CTD PMID:30259074 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases activity
multiple interactions
ISO rubiarbonone C results in decreased activity of CYP4F3 protein alternative form
rubiarbonone C inhibits the reaction [CYP4F3 protein alternative form results in increased hydroxylation of Arachidonic Acid]
CTD PMID:30259074 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      atom 19916
        nonmetal atom 19852
          carbon atom 19806
            organic molecular entity 19806
              aliphatic compound 14366
                alicyclic compound 1823
                  alicyclic ketone 1151
                    (2S,3S,4S)-2-methoxy-3-[(2E)-6-methylhept-2-en-2-yl]-4-(trifluoroacetyl)cyclohexanone 0
                    (2S,3S,4S)-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-methoxy-3-[(2E)-6-methylhept-2-en-2-yl]cyclohexanone 0
                    (2S,3S,4S)-4-acetyl-2-methoxy-3-[(2E)-6-methylhept-2-en-2-yl]cyclohexanone 0
                    (Z,S)-cinerolone 0
                    (Z,S)-jasmolone 0
                    17-phenyl-18,19,20-trinor-prostaglandin D2 0
                    17-phenyl-18,19,20-trinor-prostaglandin E2 0
                    2-cyclopenten-1-one 3
                    2-epi-5-epi-valiolone + 0
                    2-epi-5-epi-valiolone 7-phosphate 0
                    2-epi-valiolone 0
                    2-methoxyestrone + 1
                    3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydroinden-4-yl]propanoic acid + 0
                    3-dehydro-D-glucoside 0
                    3-dehydro-D-guloside 0
                    3-dehydropyranoside + 0
                    3-oxocyclopentanecarbonitrile 0
                    3-oxocyclopentanecarboxylic acid 0
                    5-epi-valiolone + 0
                    5-epi-valiolone 7-phosphate 0
                    [(S)-3-oxocyclohexyl]acetic acid 0
                    anticapsin 0
                    bacilysin 0
                    beta-bitter acid + 0
                    bicyclo[2.2.2]octane-2,6-dione 0
                    cyclic terpene ketone + 146
                    cyclobutenone + 0
                    cyclobutenones + 0
                    cyclohexanones + 865
                    cyclohexenones + 119
                    cyclopentanones + 45
                    cyclopropenone + 14
                    myrothenone A 0
                    paeoniflorigenone 0
                    petasin 0
                    prostaglandin D2 1-glyceryl ester 0
                    prostaglandin D2 2-glyceryl ester 0
                    prostaglandin E2 1-glyceryl ester 0
                    prostaglandin E2 2-glyceryl ester 0
                    prostaglandins D + 145
                    pyrethrolone + 0
                    squaric acid + 0
                    valiolone + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      ketone 17210
                                        cyclic ketone 15715
                                          alicyclic ketone 1151
                                            (2S,3S,4S)-2-methoxy-3-[(2E)-6-methylhept-2-en-2-yl]-4-(trifluoroacetyl)cyclohexanone 0
                                            (2S,3S,4S)-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-methoxy-3-[(2E)-6-methylhept-2-en-2-yl]cyclohexanone 0
                                            (2S,3S,4S)-4-acetyl-2-methoxy-3-[(2E)-6-methylhept-2-en-2-yl]cyclohexanone 0
                                            (Z,S)-cinerolone 0
                                            (Z,S)-jasmolone 0
                                            17-phenyl-18,19,20-trinor-prostaglandin D2 0
                                            17-phenyl-18,19,20-trinor-prostaglandin E2 0
                                            2-cyclopenten-1-one 3
                                            2-epi-5-epi-valiolone + 0
                                            2-epi-5-epi-valiolone 7-phosphate 0
                                            2-epi-valiolone 0
                                            2-methoxyestrone + 1
                                            3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydroinden-4-yl]propanoic acid + 0
                                            3-dehydro-D-glucoside 0
                                            3-dehydro-D-guloside 0
                                            3-dehydropyranoside + 0
                                            3-oxocyclopentanecarbonitrile 0
                                            3-oxocyclopentanecarboxylic acid 0
                                            5-epi-valiolone + 0
                                            5-epi-valiolone 7-phosphate 0
                                            [(S)-3-oxocyclohexyl]acetic acid 0
                                            anticapsin 0
                                            bacilysin 0
                                            beta-bitter acid + 0
                                            bicyclo[2.2.2]octane-2,6-dione 0
                                            cyclic terpene ketone + 146
                                            cyclobutenone + 0
                                            cyclobutenones + 0
                                            cyclohexanones + 865
                                            cyclohexenones + 119
                                            cyclopentanones + 45
                                            cyclopropenone + 14
                                            myrothenone A 0
                                            paeoniflorigenone 0
                                            petasin 0
                                            prostaglandin D2 1-glyceryl ester 0
                                            prostaglandin D2 2-glyceryl ester 0
                                            prostaglandin E2 1-glyceryl ester 0
                                            prostaglandin E2 2-glyceryl ester 0
                                            prostaglandins D + 145
                                            pyrethrolone + 0
                                            squaric acid + 0
                                            valiolone + 0
paths to the root