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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chlordiazepoxide
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Accession:CHEBI:3611 term browser browse the term
Definition:A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.
Synonyms:exact_synonym: 7-chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide
 related_synonym: 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide;   CDP;   Formula=C16H14ClN3O;   Helogaphen;   InChI=1S/C16H14ClN3O/c1-18-15-10-20(21)16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)19-15/h2-9H,10H2,1H3,(H,18,19);   InChIKey=ANTSCNMPPGJYLG-UHFFFAOYSA-N;   Libritabs;   Multum;   Risolid;   SMILES=CNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=N(=O)C1;   Silibrin;   Tropium;   chlordiazepoxide base;   chlordiazepoxidum;   clopoxide;   methaminodiazepoxide
 xref: Beilstein:550356;   CAS:58-25-3;   DrugBank:DB00475;   Drug_Central:594;   HMDB:HMDB0014618;   KEGG:D00267
 xref_mesh: MESH:D002707
 xref: PMID:17049372;   PMID:19643124;   PMID:9632243;   Patent:MY6500040;   Patent:US2893992;   Patent:US3122474;   Reaxys:550356;   Wikipedia:Chlordiazepoxide


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chlordiazepoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases activity ISO Chlordiazepoxide results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Gabre gamma-aminobutyric acid (GABA) A receptor, subunit epsilon decreases response to substance ISO GABRE protein results in decreased susceptibility to Chlordiazepoxide CTD PMID:11691872 NCBI chr  X:71,300,532...71,318,433
Ensembl chr  X:71,299,605...71,318,409 		JBrowse link
G Trh thyrotropin releasing hormone multiple interactions ISO Chlordiazepoxide inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631 		JBrowse link
G Trhr thyrotropin releasing hormone receptor multiple interactions ISO Chlordiazepoxide inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr15:44,059,314...44,099,308
Ensembl chr15:44,059,531...44,099,308 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        pharmaceutical 21187
          adjuvant 4705
            anaesthesia adjuvant 216
              chlordiazepoxide 4
                chlordiazepoxide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  azane 18426
                                    ammonia 18425
                                      organic amino compound 18425
                                        secondary amino compound 6882
                                          chlordiazepoxide 4
                                            chlordiazepoxide hydrochloride 0
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